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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:RBM10-PHF16 (FusionGDB2 ID:72290)

Fusion Gene Summary for RBM10-PHF16

check button Fusion gene summary
Fusion gene informationFusion gene name: RBM10-PHF16
Fusion gene ID: 72290
HgeneTgene
Gene symbol

RBM10

PHF16

Gene ID

8241

9767

Gene nameRNA binding motif protein 10jade family PHD finger 3
SynonymsDXS8237E|GPATC9|GPATCH9|S1-1|TARPS|ZRANB5JADE-3|PHF16
Cytomap

Xp11.3

Xp11.3

Type of geneprotein-codingprotein-coding
DescriptionRNA-binding protein 10RNA-binding protein S1-1epididymis secretory sperm binding proteing patch domain-containing protein 9protein Jade-3PHD finger protein 16jade family PHD finger protein 3
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000377604, ENST00000329236, 
ENST00000345781, ENST00000478410, 
ENST00000397189, ENST00000218343, 
Fusion gene scores* DoF score17 X 8 X 9=12244 X 3 X 4=48
# samples 184
** MAII scorelog2(18/1224*10)=-2.76553474636298
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/48*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RBM10 [Title/Abstract] AND PHF16 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRBM10(47028897)-PHF16(46857522), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgenePHF16

GO:0043966

histone H3 acetylation

16387653

TgenePHF16

GO:0043981

histone H4-K5 acetylation

16387653

TgenePHF16

GO:0043982

histone H4-K8 acetylation

16387653

TgenePHF16

GO:0043983

histone H4-K12 acetylation

16387653

TgenePHF16

GO:0043984

histone H4-K16 acetylation

16387653


check buttonFusion gene breakpoints across RBM10 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across PHF16 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-D8-A1JB-01ARBM10chrX

47028897

-PHF16chrX

46857522

+


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Fusion Gene ORF analysis for RBM10-PHF16

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000377604ENST00000397189RBM10chrX

47028897

-PHF16chrX

46857522

+
In-frameENST00000377604ENST00000218343RBM10chrX

47028897

-PHF16chrX

46857522

+
In-frameENST00000329236ENST00000397189RBM10chrX

47028897

-PHF16chrX

46857522

+
In-frameENST00000329236ENST00000218343RBM10chrX

47028897

-PHF16chrX

46857522

+
In-frameENST00000345781ENST00000397189RBM10chrX

47028897

-PHF16chrX

46857522

+
In-frameENST00000345781ENST00000218343RBM10chrX

47028897

-PHF16chrX

46857522

+
intron-3CDSENST00000478410ENST00000397189RBM10chrX

47028897

-PHF16chrX

46857522

+
intron-3CDSENST00000478410ENST00000218343RBM10chrX

47028897

-PHF16chrX

46857522

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000377604RBM10chrX47028897-ENST00000397189PHF16chrX46857522+54519434243288954
ENST00000377604RBM10chrX47028897-ENST00000218343PHF16chrX46857522+54509434243288954
ENST00000329236RBM10chrX47028897-ENST00000397189PHF16chrX46857522+5088580612925954
ENST00000329236RBM10chrX47028897-ENST00000218343PHF16chrX46857522+5087580612925954
ENST00000345781RBM10chrX47028897-ENST00000397189PHF16chrX46857522+5041533142878954
ENST00000345781RBM10chrX47028897-ENST00000218343PHF16chrX46857522+5040533142878954

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000377604ENST00000397189RBM10chrX47028897-PHF16chrX46857522+0.000237330.9997627
ENST00000377604ENST00000218343RBM10chrX47028897-PHF16chrX46857522+0.0002360780.9997639
ENST00000329236ENST00000397189RBM10chrX47028897-PHF16chrX46857522+0.0002270430.99977297
ENST00000329236ENST00000218343RBM10chrX47028897-PHF16chrX46857522+0.0002259880.99977404
ENST00000345781ENST00000397189RBM10chrX47028897-PHF16chrX46857522+0.0002284360.99977154
ENST00000345781ENST00000218343RBM10chrX47028897-PHF16chrX46857522+0.0002272820.9997727

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Fusion Genomic Features for RBM10-PHF16


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for RBM10-PHF16


check button Go to

FGviewer for the breakpoints of chrX:47028897-chrX:46857522

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRBM10chrX:47028897chrX:46857522ENST00000329236-323113_12567.0853.0Compositional biasNote=Poly-Glu
HgeneRBM10chrX:47028897chrX:46857522ENST00000329236-323561_60767.0853.0Compositional biasNote=Tyr-rich
HgeneRBM10chrX:47028897chrX:46857522ENST00000329236-32380_8767.0853.0Compositional biasNote=Poly-Arg
HgeneRBM10chrX:47028897chrX:46857522ENST00000345781-323113_12567.0854.0Compositional biasNote=Poly-Glu
HgeneRBM10chrX:47028897chrX:46857522ENST00000345781-323561_60767.0854.0Compositional biasNote=Tyr-rich
HgeneRBM10chrX:47028897chrX:46857522ENST00000345781-32380_8767.0854.0Compositional biasNote=Poly-Arg
HgeneRBM10chrX:47028897chrX:46857522ENST00000377604-324113_12567.0931.0Compositional biasNote=Poly-Glu
HgeneRBM10chrX:47028897chrX:46857522ENST00000377604-324561_60767.0931.0Compositional biasNote=Tyr-rich
HgeneRBM10chrX:47028897chrX:46857522ENST00000377604-32480_8767.0931.0Compositional biasNote=Poly-Arg
HgeneRBM10chrX:47028897chrX:46857522ENST00000329236-323129_20967.0853.0DomainRRM 1
HgeneRBM10chrX:47028897chrX:46857522ENST00000329236-323300_38467.0853.0DomainRRM 2
HgeneRBM10chrX:47028897chrX:46857522ENST00000329236-323858_90467.0853.0DomainG-patch
HgeneRBM10chrX:47028897chrX:46857522ENST00000345781-323129_20967.0854.0DomainRRM 1
HgeneRBM10chrX:47028897chrX:46857522ENST00000345781-323300_38467.0854.0DomainRRM 2
HgeneRBM10chrX:47028897chrX:46857522ENST00000345781-323858_90467.0854.0DomainG-patch
HgeneRBM10chrX:47028897chrX:46857522ENST00000377604-324129_20967.0931.0DomainRRM 1
HgeneRBM10chrX:47028897chrX:46857522ENST00000377604-324300_38467.0931.0DomainRRM 2
HgeneRBM10chrX:47028897chrX:46857522ENST00000377604-324858_90467.0931.0DomainG-patch
HgeneRBM10chrX:47028897chrX:46857522ENST00000329236-323212_24267.0853.0Zinc fingerRanBP2-type
HgeneRBM10chrX:47028897chrX:46857522ENST00000329236-323759_78467.0853.0Zinc fingerC2H2-type%3B atypical
HgeneRBM10chrX:47028897chrX:46857522ENST00000345781-323212_24267.0854.0Zinc fingerRanBP2-type
HgeneRBM10chrX:47028897chrX:46857522ENST00000345781-323759_78467.0854.0Zinc fingerC2H2-type%3B atypical
HgeneRBM10chrX:47028897chrX:46857522ENST00000377604-324212_24267.0931.0Zinc fingerRanBP2-type
HgeneRBM10chrX:47028897chrX:46857522ENST00000377604-324759_78467.0931.0Zinc fingerC2H2-type%3B atypical


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Fusion Gene Sequence for RBM10-PHF16


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000377604_ENST00000397189_TCGA-D8-A1JB-01A_RBM10_chrX_47028897_-_PHF16_chrX_46857522_length(transcript)=5451nt_BP=943nt
GCCAACCATTTTCGGCCAGGCTGAGAAATTTCTTATTGATGGGTCTGCTCATTTCCTGCATAGGAAGAAATCGGTGACATTTGGGTGGAT
ACAGTTCCCAGCCAATCGCCCCGAGTTCCCTCGCCCACTGGGGAAAGAGGCAGAGCTTCCGCTAGTCTTTCATCTTCAAAGGAAATCAAG
CTTCTAAAAAGCGGGCCCTGCCGAATTGGCTAATAGCTACTCCTTTTCTCCACTAGGGGAGCGTTCGCAAGGGGTGTGGGGAGGTGGCCA
GCGCTTGCCAATCAGAGGAGGCCAGGGCTGTCCCCTAGCGGGCGGTGACCAATCGCCGGGGCCGGCCAGAGCGCGCTTCCTTAGTAGGTG
GATGGTGGTCGGAGCGCCGACTCCCTTCTCGTCGTCGCCATTTTGAGCTGGTGACTGTGGCCGGCTGGGAGTAGGCGGCAGTGAGTTTCC
CTGGGAGGGCAGCGCGCTTGGCGCTTCTCCCCTCCCCCCGATCTGCCTCCAGTCTCGGACTTGGTTGTTGCGCGCTCCGGCTCCGGCTGA
GCTGGGAGAGTTGGAGGAGGTGGCGGCGGGCAGAGGTGATGTCTGGGAGCCCTTCCTTGACAGCCCGGGCCGAGAAGAGTCCCTGCAGGA
AGCATCACCCAGGCTGGCAGATCATGGTAGCAGCAGCGGGGGTGGCTGGGAAGTGAAACGGAGCCAGCGGCTGAGGAGGGGCCCCAGCAG
CCCCCGAAGGCCCTATCAGGACATGGAGTATGAAAGACGTGGTGGTCGTGGTGACAGGACTGGCCGCTATGGAGCCACTGACCGCTCGCA
GGATGATGGTGGGGAGAACCGCAGCCGAGACCACGACTACCGGGACATGGACTACCGTTCATATCCTCGCGAGTATGGCAGCCAGGAGGG
CAAGCATGACTATGACGACTCATCTGAGGAGCAGAGTGCGGAGGTATTCCGGAAGGACCTCATCAGTGCCATGAAACTTCCAGATTCTCA
CCACATTAATCCTGATAGCTATTACCTCTTTGCTGATACATGGAAGGAAGAATGGGAAAAGGGAGTCCAGGTACCAGCCAGTCCAGACAC
CGTTCCACAGCCTTCTCTCAGGATTATAGCTGAGAAGGTAAAGGACGTTCTGTTTATCCGACCCCGGAAGTATATTCACTGCTCCAGCCC
AGACACCACAGAGCCTGGCTACATCAACATCATGGAGTTGGCAGCATCTGTTTGCCGCTATGACCTAGATGACATGGACATCTTCTGGCT
TCAGGAACTCAATGAAGACCTTGCAGAAATGGGTTGTGGGCCAGTTGATGAGAATCTTATGGAAAAGACAGTAGAAGTCCTGGAACGCCA
TTGCCATGAAAATATGAACCATGCTATTGAGACAGAGGAAGGGCTAGGCATAGAGTATGATGAAGATGTGATCTGTGATGTGTGCCGGTC
TCCAGACAGTGAAGAAGGGAATGATATGGTGTTCTGTGATAAGTGTAACGTCTGTGTGCATCAGGCCTGCTATGGCATCCTCAAGGTCCC
AGAAGGCAGCTGGCTGTGTCGCTCCTGTGTCCTGGGCATTTATCCGCAATGTGTGTTATGTCCAAAGAAAGGTGGAGCCCTGAAGACCAC
CAAGACAGGGACTAAATGGGCTCATGTCAGCTGTGCCCTGTGGATCCCAGAGGTCAGCATTGCTTGTCCTGAGAGGATGGAACCGATCAC
GAAGATCTCCCACATCCCACCCAGTCGGTGGGCCTTAGTCTGCAACTTGTGCAAGTTGAAGACGGGGGCTTGTATTCAGTGCTCTATAAA
AAGCTGCATCACTGCCTTCCACGTCACCTGTGCCTTTGAGCACGGCCTAGAGATGAAGACCATCCTAGATGAGGGAGACGAAGTGAAGTT
CAAGTCATATTGCCTCAAGCATAGCCAAAACAGGCAGAAACTTGGAGAAGCTGAGTACCCCCACCACAGGGCTAAAGAGCAGAGCCAGGC
CAAAAGTGAGAAAACCAGCCTGCGGGCACAGAAGCTTCGGGAGCTGGAGGAGGAGTTCTATTCCTTGGTACGAGTGGAAGATGTGGCCGC
AGAGCTGGGTATGCCCACGCTAGCTGTGGACTTTATCTATAACTACTGGAAACTGAAGCGGAAAAGTAACTTCAATAAGCCATTATTTCC
TCCAAAGGAGGATGAAGAAAATGGGCTGGTGCAGCCAAAAGAGGAAAGCATTCACACTCGAATGAGAATGTTTATGCATCTACGCCAGGA
CCTGGAGAGGGTCCGAAATCTGTGCTATATGATAAGCAGACGAGAGAAGCTGAAGCTGTCACACAACAAAATACAGGAACAGATCTTCGG
TTTGCAAGTCCAGCTTCTTAACCAAGAAATTGATGCAGGGCTTCCTTTGACAAATGCACTTGAAAACTCACTGTTTTACCCACCACCAAG
AATTACCTTGAAGTTAAAAATGCCCAAATCAACCCCAGAAGACCACAGAAACAGCTCCACAGAAACCGATCAGCAGCCCCACTCTCCTGA
CAGCAGCTCATCTGTTCACAGTATAAGGAACATGCAGGTGCCTCAGGAGTCACTAGAAATGAGAACAAAATCGTATCCGAGATACCCACT
AGAGAGCAAGAATAACCGTTTGCTGGCCAGTCTCAGCCATTCTAGGAGTGAAGCAAAGGAGTCCAGTCCTGCTTGGAGAACCCCGTCCTC
GGAGTGCTATCATGGGCAGTCACTGGGAAAGCCTCTGGTCCTTCAGGCTGCCCTCCATGGACAGTCTTCCATTGGGAATGGGAAAAGTCA
GCCTAACTCCAAGTTTGCCAAATCCAATGGCCTGGAGGGCAGCTGGTCTGGGAATGTCACCCAAAAAGACAGCTCGAGTGAGATGTTCTG
TGACCAGGAGCCTGTGTTCAGCCCCCACTTGGTCAGTCAGGGCAGCTTTAGAAAATCCACTGTAGAACACTTTAGTAGGTCCTTTAAAGA
GACCACCAATAGGTGGGTGAAGAACACAGAGGACCTCCAGTGCTATGTGAAGCCAACCAAGAATATGAGCCCCAAGGAGCAGTTCTGGGG
TAGACAGGTTCTCAGGCGGTCTGCAGGGAGAGCTCCATATCAGGAAAATGATGGCTATTGCCCAGATTTGGAGCTGAGTGATTCAGAGGC
AGAAAGTGATGGGAATAAAGAAAAAGTCAGGGTAAGGAAAGATAGCTCAGACAGGGAAAATCCTCCCCATGACTCTAGACGGGATTGCCA
TGGTAAAAGCAAGACACATCCCCTTTCCCACAGTTCAATGCAAAGGTGATTAGAAACTTCCAAGGATGACCCAACCTTTGCCTTTGCCCC
ATATATTGGGGAAAACCCATACACCAAAAGGATTTTAGCATATGTTAAGAGGAATTGCAGTGAAAAGGATAACATTTTTCCATAGTAAAT
TGTCTTGCAGTTTTTGAAAATGTTTCAAGTCTAGTTTTTACAAGCACATTACAGTAATTGCAGGTTGTCCAGAGGTTGGTTTGTCAGAGG
CTATTGGGAACAGCTGGGCCCAGGGTATTTGCTCAGTAAATATTTTGGGGCAGCTTTCCGGTTATATAACACATTGACAAGTATATGTAT
TAAGAGTCCTTGCATTGTTAACTGATTTGCAAGAGACCATGATTATCAGACACTAAAACTACTTATCTTTTGAAGCTACAGCATGTGACT
CCCCAGAGCTCCTGTCTGTAGGAAGTTTCTAATTCCCTGGTATCTATAAACCCTTTTCAGGGGAGAGACCGGAGACCCCATCTTAGATAC
TGTCAACTCACTACTGTCTTCCTTTGTTCTGCACAAGGTTGAGTTTCTTTCACAGTATCTTAACTTACTGAGTCAATACTCCTCATGCTT
ATCAGTGTCCAGTGCCTGTTCCTAAACTTGCTTGTTGGGGACACACTCATAACTATTTCACCTGACTGACAAGCATAAAAGGCTAACTTG
TGGATAGTGTTTACAAAAGTACAAAAGTACTACTTCCAAGGAAAATGCTCTGATTCTCTGTTTAGGCATTTGTGAAGGATTCCAGAGCCT
TTCCCAAAGTGAGACCATTTCTGGGGTATTTGTACCAGGTCAGGGTTTTTGTGTTGTTTTCAAATAAGTTTGACTAAAATAAGTTTGGCT
GACAGTTTTTGTATACCTGCTTTAATGTTTATAAAATTTTTATTGAGGTATAATTAAAATATAGTAAAATGCACAGAGGTTAAGTATTCT
TACCTGCTTTAATTTTGAAACAGATTTTTATTGTCAAACAGAATTTGAAAGCATGTGTTTAACACATGGATATAATTTAGCTTTGTGTCA
CCTTTGAATCTGAGGCAGTTTCCCAAACAAAAAGGCTGGAGCCATTTTTCAGAAGTTGCTTATACCCTGTTCCCAAACTATCAGCCTTGA
TTAATTTCTAGTAGGAAGAGAATAATTACATTTGCGGGGGGGGGGGTGGATAAAAAACATGTCTGCTTCTCATTTAAATAAGAGAGAAAT
GATGCCGTTTTTTAAATGTGAAGCAGACTATAATTCTCAGCTCTCTTTTCTTCTTAGCCTTAAATTAATATTCTCTTTCTTCTAGTTTTG
GAAAGTGTAGTGGGAATATTCAGACAAAAGAGGCCATTTTCCATTTTTAAAGCTTCTTACTGGTGAAACAGCCCAGTTGTAGTAGGTGCC
AGTCAGTCAAGGCAGGGGCCCTCTCTCCGTCAATATGGAAAACTCAGCAGTTTTCCTCTCCCCCAGTTGTGTTCTTGTAACGTTGTTAAT
GGGTTCCTTTGCTTTTTGCTTTCTCCTTTTCTGAAAATGTATGTGTTTTGCCTCTCTTTTGGCTACATCTTCAAAATATTTCTTTTGTGC
CTATGTACATGTGTAAACATGCCATAGCATGTGTGGTAGGTGTCCTGTATTTTGTTTGGGAAAAAAACTATCAAAATGAGGAAGAGAATT
TCCCCTATTTATGCACTAGGTTTCTGTGCTTTTTCTTTGAGTTCTCTGGAGTAGATATTAATTTGATACCTTCATGGTAATGAAATTATG
ATGGAGCTGTGTTATAAATTCCTTATGTCAGAGGCCAGTGCGGTAGCCTTTGTCCCTTCATGCCTTTCAATTCTGAGTGGGAGGAAAAGC
AAACATCAAAACAGTGCTTCAGCCAAATTCCATATGTAATGCCATTGGGAGAGTATTGACTAAAATATCATTCGTCAGGGAAATATAGTT
GTAATATTTTTACAGGATATTCCTAGGTAAATGAAGGAGCCTTCAGTTGTAAATTTCAATTACCCCAAAATGTATTTGCTACATTTTGTT
GTTTGAAGTATTACCTCTTAACCTTCTTTGTTAATTTTTTTCATTTTGTCTTATATAGTCCAGTTTTCCAAGATAAGCTCAGTCCTTTTT

>In-frame_ENST00000377604_ENST00000397189_TCGA-D8-A1JB-01A_RBM10_chrX_47028897_-_PHF16_chrX_46857522_length(amino acids)=954AA_start in transcript=424_stop in transcript=3288
MGVGGSEFPWEGSALGASPLPPICLQSRTWLLRAPAPAELGELEEVAAGRGDVWEPFLDSPGREESLQEASPRLADHGSSSGGGWEVKRS
QRLRRGPSSPRRPYQDMEYERRGGRGDRTGRYGATDRSQDDGGENRSRDHDYRDMDYRSYPREYGSQEGKHDYDDSSEEQSAEVFRKDLI
SAMKLPDSHHINPDSYYLFADTWKEEWEKGVQVPASPDTVPQPSLRIIAEKVKDVLFIRPRKYIHCSSPDTTEPGYINIMELAASVCRYD
LDDMDIFWLQELNEDLAEMGCGPVDENLMEKTVEVLERHCHENMNHAIETEEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQ
ACYGILKVPEGSWLCRSCVLGIYPQCVLCPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWALVCNLCKLKT
GACIQCSIKSCITAFHVTCAFEHGLEMKTILDEGDEVKFKSYCLKHSQNRQKLGEAEYPHHRAKEQSQAKSEKTSLRAQKLRELEEEFYS
LVRVEDVAAELGMPTLAVDFIYNYWKLKRKSNFNKPLFPPKEDEENGLVQPKEESIHTRMRMFMHLRQDLERVRNLCYMISRREKLKLSH
NKIQEQIFGLQVQLLNQEIDAGLPLTNALENSLFYPPPRITLKLKMPKSTPEDHRNSSTETDQQPHSPDSSSSVHSIRNMQVPQESLEMR
TKSYPRYPLESKNNRLLASLSHSRSEAKESSPAWRTPSSECYHGQSLGKPLVLQAALHGQSSIGNGKSQPNSKFAKSNGLEGSWSGNVTQ
KDSSSEMFCDQEPVFSPHLVSQGSFRKSTVEHFSRSFKETTNRWVKNTEDLQCYVKPTKNMSPKEQFWGRQVLRRSAGRAPYQENDGYCP

--------------------------------------------------------------
>In-frame_ENST00000377604_ENST00000218343_TCGA-D8-A1JB-01A_RBM10_chrX_47028897_-_PHF16_chrX_46857522_length(transcript)=5450nt_BP=943nt
GCCAACCATTTTCGGCCAGGCTGAGAAATTTCTTATTGATGGGTCTGCTCATTTCCTGCATAGGAAGAAATCGGTGACATTTGGGTGGAT
ACAGTTCCCAGCCAATCGCCCCGAGTTCCCTCGCCCACTGGGGAAAGAGGCAGAGCTTCCGCTAGTCTTTCATCTTCAAAGGAAATCAAG
CTTCTAAAAAGCGGGCCCTGCCGAATTGGCTAATAGCTACTCCTTTTCTCCACTAGGGGAGCGTTCGCAAGGGGTGTGGGGAGGTGGCCA
GCGCTTGCCAATCAGAGGAGGCCAGGGCTGTCCCCTAGCGGGCGGTGACCAATCGCCGGGGCCGGCCAGAGCGCGCTTCCTTAGTAGGTG
GATGGTGGTCGGAGCGCCGACTCCCTTCTCGTCGTCGCCATTTTGAGCTGGTGACTGTGGCCGGCTGGGAGTAGGCGGCAGTGAGTTTCC
CTGGGAGGGCAGCGCGCTTGGCGCTTCTCCCCTCCCCCCGATCTGCCTCCAGTCTCGGACTTGGTTGTTGCGCGCTCCGGCTCCGGCTGA
GCTGGGAGAGTTGGAGGAGGTGGCGGCGGGCAGAGGTGATGTCTGGGAGCCCTTCCTTGACAGCCCGGGCCGAGAAGAGTCCCTGCAGGA
AGCATCACCCAGGCTGGCAGATCATGGTAGCAGCAGCGGGGGTGGCTGGGAAGTGAAACGGAGCCAGCGGCTGAGGAGGGGCCCCAGCAG
CCCCCGAAGGCCCTATCAGGACATGGAGTATGAAAGACGTGGTGGTCGTGGTGACAGGACTGGCCGCTATGGAGCCACTGACCGCTCGCA
GGATGATGGTGGGGAGAACCGCAGCCGAGACCACGACTACCGGGACATGGACTACCGTTCATATCCTCGCGAGTATGGCAGCCAGGAGGG
CAAGCATGACTATGACGACTCATCTGAGGAGCAGAGTGCGGAGGTATTCCGGAAGGACCTCATCAGTGCCATGAAACTTCCAGATTCTCA
CCACATTAATCCTGATAGCTATTACCTCTTTGCTGATACATGGAAGGAAGAATGGGAAAAGGGAGTCCAGGTACCAGCCAGTCCAGACAC
CGTTCCACAGCCTTCTCTCAGGATTATAGCTGAGAAGGTAAAGGACGTTCTGTTTATCCGACCCCGGAAGTATATTCACTGCTCCAGCCC
AGACACCACAGAGCCTGGCTACATCAACATCATGGAGTTGGCAGCATCTGTTTGCCGCTATGACCTAGATGACATGGACATCTTCTGGCT
TCAGGAACTCAATGAAGACCTTGCAGAAATGGGTTGTGGGCCAGTTGATGAGAATCTTATGGAAAAGACAGTAGAAGTCCTGGAACGCCA
TTGCCATGAAAATATGAACCATGCTATTGAGACAGAGGAAGGGCTAGGCATAGAGTATGATGAAGATGTGATCTGTGATGTGTGCCGGTC
TCCAGACAGTGAAGAAGGGAATGATATGGTGTTCTGTGATAAGTGTAACGTCTGTGTGCATCAGGCCTGCTATGGCATCCTCAAGGTCCC
AGAAGGCAGCTGGCTGTGTCGCTCCTGTGTCCTGGGCATTTATCCGCAATGTGTGTTATGTCCAAAGAAAGGTGGAGCCCTGAAGACCAC
CAAGACAGGGACTAAATGGGCTCATGTCAGCTGTGCCCTGTGGATCCCAGAGGTCAGCATTGCTTGTCCTGAGAGGATGGAACCGATCAC
GAAGATCTCCCACATCCCACCCAGTCGGTGGGCCTTAGTCTGCAACTTGTGCAAGTTGAAGACGGGGGCTTGTATTCAGTGCTCTATAAA
AAGCTGCATCACTGCCTTCCACGTCACCTGTGCCTTTGAGCACGGCCTAGAGATGAAGACCATCCTAGATGAGGGAGACGAAGTGAAGTT
CAAGTCATATTGCCTCAAGCATAGCCAAAACAGGCAGAAACTTGGAGAAGCTGAGTACCCCCACCACAGGGCTAAAGAGCAGAGCCAGGC
CAAAAGTGAGAAAACCAGCCTGCGGGCACAGAAGCTTCGGGAGCTGGAGGAGGAGTTCTATTCCTTGGTACGAGTGGAAGATGTGGCCGC
AGAGCTGGGTATGCCCACGCTAGCTGTGGACTTTATCTATAACTACTGGAAACTGAAGCGGAAAAGTAACTTCAATAAGCCATTATTTCC
TCCAAAGGAGGATGAAGAAAATGGGCTGGTGCAGCCAAAAGAGGAAAGCATTCACACTCGAATGAGAATGTTTATGCATCTACGCCAGGA
CCTGGAGAGGGTCCGAAATCTGTGCTATATGATAAGCAGACGAGAGAAGCTGAAGCTGTCACACAACAAAATACAGGAACAGATCTTCGG
TTTGCAAGTCCAGCTTCTTAACCAAGAAATTGATGCAGGGCTTCCTTTGACAAATGCACTTGAAAACTCACTGTTTTACCCACCACCAAG
AATTACCTTGAAGTTAAAAATGCCCAAATCAACCCCAGAAGACCACAGAAACAGCTCCACAGAAACCGATCAGCAGCCCCACTCTCCTGA
CAGCAGCTCATCTGTTCACAGTATAAGGAACATGCAGGTGCCTCAGGAGTCACTAGAAATGAGAACAAAATCGTATCCGAGATACCCACT
AGAGAGCAAGAATAACCGTTTGCTGGCCAGTCTCAGCCATTCTAGGAGTGAAGCAAAGGAGTCCAGTCCTGCTTGGAGAACCCCGTCCTC
GGAGTGCTATCATGGGCAGTCACTGGGAAAGCCTCTGGTCCTTCAGGCTGCCCTCCATGGACAGTCTTCCATTGGGAATGGGAAAAGTCA
GCCTAACTCCAAGTTTGCCAAATCCAATGGCCTGGAGGGCAGCTGGTCTGGGAATGTCACCCAAAAAGACAGCTCGAGTGAGATGTTCTG
TGACCAGGAGCCTGTGTTCAGCCCCCACTTGGTCAGTCAGGGCAGCTTTAGAAAATCCACTGTAGAACACTTTAGTAGGTCCTTTAAAGA
GACCACCAATAGGTGGGTGAAGAACACAGAGGACCTCCAGTGCTATGTGAAGCCAACCAAGAATATGAGCCCCAAGGAGCAGTTCTGGGG
TAGACAGGTTCTCAGGCGGTCTGCAGGGAGAGCTCCATATCAGGAAAATGATGGCTATTGCCCAGATTTGGAGCTGAGTGATTCAGAGGC
AGAAAGTGATGGGAATAAAGAAAAAGTCAGGGTAAGGAAAGATAGCTCAGACAGGGAAAATCCTCCCCATGACTCTAGACGGGATTGCCA
TGGTAAAAGCAAGACACATCCCCTTTCCCACAGTTCAATGCAAAGGTGATTAGAAACTTCCAAGGATGACCCAACCTTTGCCTTTGCCCC
ATATATTGGGGAAAACCCATACACCAAAAGGATTTTAGCATATGTTAAGAGGAATTGCAGTGAAAAGGATAACATTTTTCCATAGTAAAT
TGTCTTGCAGTTTTTGAAAATGTTTCAAGTCTAGTTTTTACAAGCACATTACAGTAATTGCAGGTTGTCCAGAGGTTGGTTTGTCAGAGG
CTATTGGGAACAGCTGGGCCCAGGGTATTTGCTCAGTAAATATTTTGGGGCAGCTTTCCGGTTATATAACACATTGACAAGTATATGTAT
TAAGAGTCCTTGCATTGTTAACTGATTTGCAAGAGACCATGATTATCAGACACTAAAACTACTTATCTTTTGAAGCTACAGCATGTGACT
CCCCAGAGCTCCTGTCTGTAGGAAGTTTCTAATTCCCTGGTATCTATAAACCCTTTTCAGGGGAGAGACCGGAGACCCCATCTTAGATAC
TGTCAACTCACTACTGTCTTCCTTTGTTCTGCACAAGGTTGAGTTTCTTTCACAGTATCTTAACTTACTGAGTCAATACTCCTCATGCTT
ATCAGTGTCCAGTGCCTGTTCCTAAACTTGCTTGTTGGGGACACACTCATAACTATTTCACCTGACTGACAAGCATAAAAGGCTAACTTG
TGGATAGTGTTTACAAAAGTACAAAAGTACTACTTCCAAGGAAAATGCTCTGATTCTCTGTTTAGGCATTTGTGAAGGATTCCAGAGCCT
TTCCCAAAGTGAGACCATTTCTGGGGTATTTGTACCAGGTCAGGGTTTTTGTGTTGTTTTCAAATAAGTTTGACTAAAATAAGTTTGGCT
GACAGTTTTTGTATACCTGCTTTAATGTTTATAAAATTTTTATTGAGGTATAATTAAAATATAGTAAAATGCACAGAGGTTAAGTATTCT
TACCTGCTTTAATTTTGAAACAGATTTTTATTGTCAAACAGAATTTGAAAGCATGTGTTTAACACATGGATATAATTTAGCTTTGTGTCA
CCTTTGAATCTGAGGCAGTTTCCCAAACAAAAAGGCTGGAGCCATTTTTCAGAAGTTGCTTATACCCTGTTCCCAAACTATCAGCCTTGA
TTAATTTCTAGTAGGAAGAGAATAATTACATTTGCGGGGGGGGGGGTGGATAAAAAACATGTCTGCTTCTCATTTAAATAAGAGAGAAAT
GATGCCGTTTTTTAAATGTGAAGCAGACTATAATTCTCAGCTCTCTTTTCTTCTTAGCCTTAAATTAATATTCTCTTTCTTCTAGTTTTG
GAAAGTGTAGTGGGAATATTCAGACAAAAGAGGCCATTTTCCATTTTTAAAGCTTCTTACTGGTGAAACAGCCCAGTTGTAGTAGGTGCC
AGTCAGTCAAGGCAGGGGCCCTCTCTCCGTCAATATGGAAAACTCAGCAGTTTTCCTCTCCCCCAGTTGTGTTCTTGTAACGTTGTTAAT
GGGTTCCTTTGCTTTTTGCTTTCTCCTTTTCTGAAAATGTATGTGTTTTGCCTCTCTTTTGGCTACATCTTCAAAATATTTCTTTTGTGC
CTATGTACATGTGTAAACATGCCATAGCATGTGTGGTAGGTGTCCTGTATTTTGTTTGGGAAAAAAACTATCAAAATGAGGAAGAGAATT
TCCCCTATTTATGCACTAGGTTTCTGTGCTTTTTCTTTGAGTTCTCTGGAGTAGATATTAATTTGATACCTTCATGGTAATGAAATTATG
ATGGAGCTGTGTTATAAATTCCTTATGTCAGAGGCCAGTGCGGTAGCCTTTGTCCCTTCATGCCTTTCAATTCTGAGTGGGAGGAAAAGC
AAACATCAAAACAGTGCTTCAGCCAAATTCCATATGTAATGCCATTGGGAGAGTATTGACTAAAATATCATTCGTCAGGGAAATATAGTT
GTAATATTTTTACAGGATATTCCTAGGTAAATGAAGGAGCCTTCAGTTGTAAATTTCAATTACCCCAAAATGTATTTGCTACATTTTGTT
GTTTGAAGTATTACCTCTTAACCTTCTTTGTTAATTTTTTTCATTTTGTCTTATATAGTCCAGTTTTCCAAGATAAGCTCAGTCCTTTTT

>In-frame_ENST00000377604_ENST00000218343_TCGA-D8-A1JB-01A_RBM10_chrX_47028897_-_PHF16_chrX_46857522_length(amino acids)=954AA_start in transcript=424_stop in transcript=3288
MGVGGSEFPWEGSALGASPLPPICLQSRTWLLRAPAPAELGELEEVAAGRGDVWEPFLDSPGREESLQEASPRLADHGSSSGGGWEVKRS
QRLRRGPSSPRRPYQDMEYERRGGRGDRTGRYGATDRSQDDGGENRSRDHDYRDMDYRSYPREYGSQEGKHDYDDSSEEQSAEVFRKDLI
SAMKLPDSHHINPDSYYLFADTWKEEWEKGVQVPASPDTVPQPSLRIIAEKVKDVLFIRPRKYIHCSSPDTTEPGYINIMELAASVCRYD
LDDMDIFWLQELNEDLAEMGCGPVDENLMEKTVEVLERHCHENMNHAIETEEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQ
ACYGILKVPEGSWLCRSCVLGIYPQCVLCPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWALVCNLCKLKT
GACIQCSIKSCITAFHVTCAFEHGLEMKTILDEGDEVKFKSYCLKHSQNRQKLGEAEYPHHRAKEQSQAKSEKTSLRAQKLRELEEEFYS
LVRVEDVAAELGMPTLAVDFIYNYWKLKRKSNFNKPLFPPKEDEENGLVQPKEESIHTRMRMFMHLRQDLERVRNLCYMISRREKLKLSH
NKIQEQIFGLQVQLLNQEIDAGLPLTNALENSLFYPPPRITLKLKMPKSTPEDHRNSSTETDQQPHSPDSSSSVHSIRNMQVPQESLEMR
TKSYPRYPLESKNNRLLASLSHSRSEAKESSPAWRTPSSECYHGQSLGKPLVLQAALHGQSSIGNGKSQPNSKFAKSNGLEGSWSGNVTQ
KDSSSEMFCDQEPVFSPHLVSQGSFRKSTVEHFSRSFKETTNRWVKNTEDLQCYVKPTKNMSPKEQFWGRQVLRRSAGRAPYQENDGYCP

--------------------------------------------------------------
>In-frame_ENST00000329236_ENST00000397189_TCGA-D8-A1JB-01A_RBM10_chrX_47028897_-_PHF16_chrX_46857522_length(transcript)=5088nt_BP=580nt
GGTGGTCGGAGCGCCGACTCCCTTCTCGTCGTCGCCATTTTGAGCTGGTGACTGTGGCCGGCTGGGAGTAGGCGGCAGTGAGTTTCCCTG
GGAGGGCAGCGCGCTTGGCGCTTCTCCCCTCCCCCCGATCTGCCTCCAGTCTCGGACTTGGTTGTTGCGCGCTCCGGCTCCGGCTGAGCT
GGGAGAGTTGGAGGAGGTGGCGGCGGGCAGAGGTGATGTCTGGGAGCCCTTCCTTGACAGCCCGGGCCGAGAAGAGTCCCTGCAGGAAGC
ATCACCCAGGCTGGCAGATCATGGTAGCAGCAGCGGGGGTGGCTGGGAAGTGAAACGGAGCCAGCGGCTGAGGAGGGGCCCCAGCAGCCC
CCGAAGGCCCTATCAGGACATGGAGTATGAAAGACGTGGTGGTCGTGGTGACAGGACTGGCCGCTATGGAGCCACTGACCGCTCGCAGGA
TGATGGTGGGGAGAACCGCAGCCGAGACCACGACTACCGGGACATGGACTACCGTTCATATCCTCGCGAGTATGGCAGCCAGGAGGGCAA
GCATGACTATGACGACTCATCTGAGGAGCAGAGTGCGGAGGTATTCCGGAAGGACCTCATCAGTGCCATGAAACTTCCAGATTCTCACCA
CATTAATCCTGATAGCTATTACCTCTTTGCTGATACATGGAAGGAAGAATGGGAAAAGGGAGTCCAGGTACCAGCCAGTCCAGACACCGT
TCCACAGCCTTCTCTCAGGATTATAGCTGAGAAGGTAAAGGACGTTCTGTTTATCCGACCCCGGAAGTATATTCACTGCTCCAGCCCAGA
CACCACAGAGCCTGGCTACATCAACATCATGGAGTTGGCAGCATCTGTTTGCCGCTATGACCTAGATGACATGGACATCTTCTGGCTTCA
GGAACTCAATGAAGACCTTGCAGAAATGGGTTGTGGGCCAGTTGATGAGAATCTTATGGAAAAGACAGTAGAAGTCCTGGAACGCCATTG
CCATGAAAATATGAACCATGCTATTGAGACAGAGGAAGGGCTAGGCATAGAGTATGATGAAGATGTGATCTGTGATGTGTGCCGGTCTCC
AGACAGTGAAGAAGGGAATGATATGGTGTTCTGTGATAAGTGTAACGTCTGTGTGCATCAGGCCTGCTATGGCATCCTCAAGGTCCCAGA
AGGCAGCTGGCTGTGTCGCTCCTGTGTCCTGGGCATTTATCCGCAATGTGTGTTATGTCCAAAGAAAGGTGGAGCCCTGAAGACCACCAA
GACAGGGACTAAATGGGCTCATGTCAGCTGTGCCCTGTGGATCCCAGAGGTCAGCATTGCTTGTCCTGAGAGGATGGAACCGATCACGAA
GATCTCCCACATCCCACCCAGTCGGTGGGCCTTAGTCTGCAACTTGTGCAAGTTGAAGACGGGGGCTTGTATTCAGTGCTCTATAAAAAG
CTGCATCACTGCCTTCCACGTCACCTGTGCCTTTGAGCACGGCCTAGAGATGAAGACCATCCTAGATGAGGGAGACGAAGTGAAGTTCAA
GTCATATTGCCTCAAGCATAGCCAAAACAGGCAGAAACTTGGAGAAGCTGAGTACCCCCACCACAGGGCTAAAGAGCAGAGCCAGGCCAA
AAGTGAGAAAACCAGCCTGCGGGCACAGAAGCTTCGGGAGCTGGAGGAGGAGTTCTATTCCTTGGTACGAGTGGAAGATGTGGCCGCAGA
GCTGGGTATGCCCACGCTAGCTGTGGACTTTATCTATAACTACTGGAAACTGAAGCGGAAAAGTAACTTCAATAAGCCATTATTTCCTCC
AAAGGAGGATGAAGAAAATGGGCTGGTGCAGCCAAAAGAGGAAAGCATTCACACTCGAATGAGAATGTTTATGCATCTACGCCAGGACCT
GGAGAGGGTCCGAAATCTGTGCTATATGATAAGCAGACGAGAGAAGCTGAAGCTGTCACACAACAAAATACAGGAACAGATCTTCGGTTT
GCAAGTCCAGCTTCTTAACCAAGAAATTGATGCAGGGCTTCCTTTGACAAATGCACTTGAAAACTCACTGTTTTACCCACCACCAAGAAT
TACCTTGAAGTTAAAAATGCCCAAATCAACCCCAGAAGACCACAGAAACAGCTCCACAGAAACCGATCAGCAGCCCCACTCTCCTGACAG
CAGCTCATCTGTTCACAGTATAAGGAACATGCAGGTGCCTCAGGAGTCACTAGAAATGAGAACAAAATCGTATCCGAGATACCCACTAGA
GAGCAAGAATAACCGTTTGCTGGCCAGTCTCAGCCATTCTAGGAGTGAAGCAAAGGAGTCCAGTCCTGCTTGGAGAACCCCGTCCTCGGA
GTGCTATCATGGGCAGTCACTGGGAAAGCCTCTGGTCCTTCAGGCTGCCCTCCATGGACAGTCTTCCATTGGGAATGGGAAAAGTCAGCC
TAACTCCAAGTTTGCCAAATCCAATGGCCTGGAGGGCAGCTGGTCTGGGAATGTCACCCAAAAAGACAGCTCGAGTGAGATGTTCTGTGA
CCAGGAGCCTGTGTTCAGCCCCCACTTGGTCAGTCAGGGCAGCTTTAGAAAATCCACTGTAGAACACTTTAGTAGGTCCTTTAAAGAGAC
CACCAATAGGTGGGTGAAGAACACAGAGGACCTCCAGTGCTATGTGAAGCCAACCAAGAATATGAGCCCCAAGGAGCAGTTCTGGGGTAG
ACAGGTTCTCAGGCGGTCTGCAGGGAGAGCTCCATATCAGGAAAATGATGGCTATTGCCCAGATTTGGAGCTGAGTGATTCAGAGGCAGA
AAGTGATGGGAATAAAGAAAAAGTCAGGGTAAGGAAAGATAGCTCAGACAGGGAAAATCCTCCCCATGACTCTAGACGGGATTGCCATGG
TAAAAGCAAGACACATCCCCTTTCCCACAGTTCAATGCAAAGGTGATTAGAAACTTCCAAGGATGACCCAACCTTTGCCTTTGCCCCATA
TATTGGGGAAAACCCATACACCAAAAGGATTTTAGCATATGTTAAGAGGAATTGCAGTGAAAAGGATAACATTTTTCCATAGTAAATTGT
CTTGCAGTTTTTGAAAATGTTTCAAGTCTAGTTTTTACAAGCACATTACAGTAATTGCAGGTTGTCCAGAGGTTGGTTTGTCAGAGGCTA
TTGGGAACAGCTGGGCCCAGGGTATTTGCTCAGTAAATATTTTGGGGCAGCTTTCCGGTTATATAACACATTGACAAGTATATGTATTAA
GAGTCCTTGCATTGTTAACTGATTTGCAAGAGACCATGATTATCAGACACTAAAACTACTTATCTTTTGAAGCTACAGCATGTGACTCCC
CAGAGCTCCTGTCTGTAGGAAGTTTCTAATTCCCTGGTATCTATAAACCCTTTTCAGGGGAGAGACCGGAGACCCCATCTTAGATACTGT
CAACTCACTACTGTCTTCCTTTGTTCTGCACAAGGTTGAGTTTCTTTCACAGTATCTTAACTTACTGAGTCAATACTCCTCATGCTTATC
AGTGTCCAGTGCCTGTTCCTAAACTTGCTTGTTGGGGACACACTCATAACTATTTCACCTGACTGACAAGCATAAAAGGCTAACTTGTGG
ATAGTGTTTACAAAAGTACAAAAGTACTACTTCCAAGGAAAATGCTCTGATTCTCTGTTTAGGCATTTGTGAAGGATTCCAGAGCCTTTC
CCAAAGTGAGACCATTTCTGGGGTATTTGTACCAGGTCAGGGTTTTTGTGTTGTTTTCAAATAAGTTTGACTAAAATAAGTTTGGCTGAC
AGTTTTTGTATACCTGCTTTAATGTTTATAAAATTTTTATTGAGGTATAATTAAAATATAGTAAAATGCACAGAGGTTAAGTATTCTTAC
CTGCTTTAATTTTGAAACAGATTTTTATTGTCAAACAGAATTTGAAAGCATGTGTTTAACACATGGATATAATTTAGCTTTGTGTCACCT
TTGAATCTGAGGCAGTTTCCCAAACAAAAAGGCTGGAGCCATTTTTCAGAAGTTGCTTATACCCTGTTCCCAAACTATCAGCCTTGATTA
ATTTCTAGTAGGAAGAGAATAATTACATTTGCGGGGGGGGGGGTGGATAAAAAACATGTCTGCTTCTCATTTAAATAAGAGAGAAATGAT
GCCGTTTTTTAAATGTGAAGCAGACTATAATTCTCAGCTCTCTTTTCTTCTTAGCCTTAAATTAATATTCTCTTTCTTCTAGTTTTGGAA
AGTGTAGTGGGAATATTCAGACAAAAGAGGCCATTTTCCATTTTTAAAGCTTCTTACTGGTGAAACAGCCCAGTTGTAGTAGGTGCCAGT
CAGTCAAGGCAGGGGCCCTCTCTCCGTCAATATGGAAAACTCAGCAGTTTTCCTCTCCCCCAGTTGTGTTCTTGTAACGTTGTTAATGGG
TTCCTTTGCTTTTTGCTTTCTCCTTTTCTGAAAATGTATGTGTTTTGCCTCTCTTTTGGCTACATCTTCAAAATATTTCTTTTGTGCCTA
TGTACATGTGTAAACATGCCATAGCATGTGTGGTAGGTGTCCTGTATTTTGTTTGGGAAAAAAACTATCAAAATGAGGAAGAGAATTTCC
CCTATTTATGCACTAGGTTTCTGTGCTTTTTCTTTGAGTTCTCTGGAGTAGATATTAATTTGATACCTTCATGGTAATGAAATTATGATG
GAGCTGTGTTATAAATTCCTTATGTCAGAGGCCAGTGCGGTAGCCTTTGTCCCTTCATGCCTTTCAATTCTGAGTGGGAGGAAAAGCAAA
CATCAAAACAGTGCTTCAGCCAAATTCCATATGTAATGCCATTGGGAGAGTATTGACTAAAATATCATTCGTCAGGGAAATATAGTTGTA
ATATTTTTACAGGATATTCCTAGGTAAATGAAGGAGCCTTCAGTTGTAAATTTCAATTACCCCAAAATGTATTTGCTACATTTTGTTGTT
TGAAGTATTACCTCTTAACCTTCTTTGTTAATTTTTTTCATTTTGTCTTATATAGTCCAGTTTTCCAAGATAAGCTCAGTCCTTTTTCAA

>In-frame_ENST00000329236_ENST00000397189_TCGA-D8-A1JB-01A_RBM10_chrX_47028897_-_PHF16_chrX_46857522_length(amino acids)=954AA_start in transcript=61_stop in transcript=2925
MGVGGSEFPWEGSALGASPLPPICLQSRTWLLRAPAPAELGELEEVAAGRGDVWEPFLDSPGREESLQEASPRLADHGSSSGGGWEVKRS
QRLRRGPSSPRRPYQDMEYERRGGRGDRTGRYGATDRSQDDGGENRSRDHDYRDMDYRSYPREYGSQEGKHDYDDSSEEQSAEVFRKDLI
SAMKLPDSHHINPDSYYLFADTWKEEWEKGVQVPASPDTVPQPSLRIIAEKVKDVLFIRPRKYIHCSSPDTTEPGYINIMELAASVCRYD
LDDMDIFWLQELNEDLAEMGCGPVDENLMEKTVEVLERHCHENMNHAIETEEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQ
ACYGILKVPEGSWLCRSCVLGIYPQCVLCPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWALVCNLCKLKT
GACIQCSIKSCITAFHVTCAFEHGLEMKTILDEGDEVKFKSYCLKHSQNRQKLGEAEYPHHRAKEQSQAKSEKTSLRAQKLRELEEEFYS
LVRVEDVAAELGMPTLAVDFIYNYWKLKRKSNFNKPLFPPKEDEENGLVQPKEESIHTRMRMFMHLRQDLERVRNLCYMISRREKLKLSH
NKIQEQIFGLQVQLLNQEIDAGLPLTNALENSLFYPPPRITLKLKMPKSTPEDHRNSSTETDQQPHSPDSSSSVHSIRNMQVPQESLEMR
TKSYPRYPLESKNNRLLASLSHSRSEAKESSPAWRTPSSECYHGQSLGKPLVLQAALHGQSSIGNGKSQPNSKFAKSNGLEGSWSGNVTQ
KDSSSEMFCDQEPVFSPHLVSQGSFRKSTVEHFSRSFKETTNRWVKNTEDLQCYVKPTKNMSPKEQFWGRQVLRRSAGRAPYQENDGYCP

--------------------------------------------------------------
>In-frame_ENST00000329236_ENST00000218343_TCGA-D8-A1JB-01A_RBM10_chrX_47028897_-_PHF16_chrX_46857522_length(transcript)=5087nt_BP=580nt
GGTGGTCGGAGCGCCGACTCCCTTCTCGTCGTCGCCATTTTGAGCTGGTGACTGTGGCCGGCTGGGAGTAGGCGGCAGTGAGTTTCCCTG
GGAGGGCAGCGCGCTTGGCGCTTCTCCCCTCCCCCCGATCTGCCTCCAGTCTCGGACTTGGTTGTTGCGCGCTCCGGCTCCGGCTGAGCT
GGGAGAGTTGGAGGAGGTGGCGGCGGGCAGAGGTGATGTCTGGGAGCCCTTCCTTGACAGCCCGGGCCGAGAAGAGTCCCTGCAGGAAGC
ATCACCCAGGCTGGCAGATCATGGTAGCAGCAGCGGGGGTGGCTGGGAAGTGAAACGGAGCCAGCGGCTGAGGAGGGGCCCCAGCAGCCC
CCGAAGGCCCTATCAGGACATGGAGTATGAAAGACGTGGTGGTCGTGGTGACAGGACTGGCCGCTATGGAGCCACTGACCGCTCGCAGGA
TGATGGTGGGGAGAACCGCAGCCGAGACCACGACTACCGGGACATGGACTACCGTTCATATCCTCGCGAGTATGGCAGCCAGGAGGGCAA
GCATGACTATGACGACTCATCTGAGGAGCAGAGTGCGGAGGTATTCCGGAAGGACCTCATCAGTGCCATGAAACTTCCAGATTCTCACCA
CATTAATCCTGATAGCTATTACCTCTTTGCTGATACATGGAAGGAAGAATGGGAAAAGGGAGTCCAGGTACCAGCCAGTCCAGACACCGT
TCCACAGCCTTCTCTCAGGATTATAGCTGAGAAGGTAAAGGACGTTCTGTTTATCCGACCCCGGAAGTATATTCACTGCTCCAGCCCAGA
CACCACAGAGCCTGGCTACATCAACATCATGGAGTTGGCAGCATCTGTTTGCCGCTATGACCTAGATGACATGGACATCTTCTGGCTTCA
GGAACTCAATGAAGACCTTGCAGAAATGGGTTGTGGGCCAGTTGATGAGAATCTTATGGAAAAGACAGTAGAAGTCCTGGAACGCCATTG
CCATGAAAATATGAACCATGCTATTGAGACAGAGGAAGGGCTAGGCATAGAGTATGATGAAGATGTGATCTGTGATGTGTGCCGGTCTCC
AGACAGTGAAGAAGGGAATGATATGGTGTTCTGTGATAAGTGTAACGTCTGTGTGCATCAGGCCTGCTATGGCATCCTCAAGGTCCCAGA
AGGCAGCTGGCTGTGTCGCTCCTGTGTCCTGGGCATTTATCCGCAATGTGTGTTATGTCCAAAGAAAGGTGGAGCCCTGAAGACCACCAA
GACAGGGACTAAATGGGCTCATGTCAGCTGTGCCCTGTGGATCCCAGAGGTCAGCATTGCTTGTCCTGAGAGGATGGAACCGATCACGAA
GATCTCCCACATCCCACCCAGTCGGTGGGCCTTAGTCTGCAACTTGTGCAAGTTGAAGACGGGGGCTTGTATTCAGTGCTCTATAAAAAG
CTGCATCACTGCCTTCCACGTCACCTGTGCCTTTGAGCACGGCCTAGAGATGAAGACCATCCTAGATGAGGGAGACGAAGTGAAGTTCAA
GTCATATTGCCTCAAGCATAGCCAAAACAGGCAGAAACTTGGAGAAGCTGAGTACCCCCACCACAGGGCTAAAGAGCAGAGCCAGGCCAA
AAGTGAGAAAACCAGCCTGCGGGCACAGAAGCTTCGGGAGCTGGAGGAGGAGTTCTATTCCTTGGTACGAGTGGAAGATGTGGCCGCAGA
GCTGGGTATGCCCACGCTAGCTGTGGACTTTATCTATAACTACTGGAAACTGAAGCGGAAAAGTAACTTCAATAAGCCATTATTTCCTCC
AAAGGAGGATGAAGAAAATGGGCTGGTGCAGCCAAAAGAGGAAAGCATTCACACTCGAATGAGAATGTTTATGCATCTACGCCAGGACCT
GGAGAGGGTCCGAAATCTGTGCTATATGATAAGCAGACGAGAGAAGCTGAAGCTGTCACACAACAAAATACAGGAACAGATCTTCGGTTT
GCAAGTCCAGCTTCTTAACCAAGAAATTGATGCAGGGCTTCCTTTGACAAATGCACTTGAAAACTCACTGTTTTACCCACCACCAAGAAT
TACCTTGAAGTTAAAAATGCCCAAATCAACCCCAGAAGACCACAGAAACAGCTCCACAGAAACCGATCAGCAGCCCCACTCTCCTGACAG
CAGCTCATCTGTTCACAGTATAAGGAACATGCAGGTGCCTCAGGAGTCACTAGAAATGAGAACAAAATCGTATCCGAGATACCCACTAGA
GAGCAAGAATAACCGTTTGCTGGCCAGTCTCAGCCATTCTAGGAGTGAAGCAAAGGAGTCCAGTCCTGCTTGGAGAACCCCGTCCTCGGA
GTGCTATCATGGGCAGTCACTGGGAAAGCCTCTGGTCCTTCAGGCTGCCCTCCATGGACAGTCTTCCATTGGGAATGGGAAAAGTCAGCC
TAACTCCAAGTTTGCCAAATCCAATGGCCTGGAGGGCAGCTGGTCTGGGAATGTCACCCAAAAAGACAGCTCGAGTGAGATGTTCTGTGA
CCAGGAGCCTGTGTTCAGCCCCCACTTGGTCAGTCAGGGCAGCTTTAGAAAATCCACTGTAGAACACTTTAGTAGGTCCTTTAAAGAGAC
CACCAATAGGTGGGTGAAGAACACAGAGGACCTCCAGTGCTATGTGAAGCCAACCAAGAATATGAGCCCCAAGGAGCAGTTCTGGGGTAG
ACAGGTTCTCAGGCGGTCTGCAGGGAGAGCTCCATATCAGGAAAATGATGGCTATTGCCCAGATTTGGAGCTGAGTGATTCAGAGGCAGA
AAGTGATGGGAATAAAGAAAAAGTCAGGGTAAGGAAAGATAGCTCAGACAGGGAAAATCCTCCCCATGACTCTAGACGGGATTGCCATGG
TAAAAGCAAGACACATCCCCTTTCCCACAGTTCAATGCAAAGGTGATTAGAAACTTCCAAGGATGACCCAACCTTTGCCTTTGCCCCATA
TATTGGGGAAAACCCATACACCAAAAGGATTTTAGCATATGTTAAGAGGAATTGCAGTGAAAAGGATAACATTTTTCCATAGTAAATTGT
CTTGCAGTTTTTGAAAATGTTTCAAGTCTAGTTTTTACAAGCACATTACAGTAATTGCAGGTTGTCCAGAGGTTGGTTTGTCAGAGGCTA
TTGGGAACAGCTGGGCCCAGGGTATTTGCTCAGTAAATATTTTGGGGCAGCTTTCCGGTTATATAACACATTGACAAGTATATGTATTAA
GAGTCCTTGCATTGTTAACTGATTTGCAAGAGACCATGATTATCAGACACTAAAACTACTTATCTTTTGAAGCTACAGCATGTGACTCCC
CAGAGCTCCTGTCTGTAGGAAGTTTCTAATTCCCTGGTATCTATAAACCCTTTTCAGGGGAGAGACCGGAGACCCCATCTTAGATACTGT
CAACTCACTACTGTCTTCCTTTGTTCTGCACAAGGTTGAGTTTCTTTCACAGTATCTTAACTTACTGAGTCAATACTCCTCATGCTTATC
AGTGTCCAGTGCCTGTTCCTAAACTTGCTTGTTGGGGACACACTCATAACTATTTCACCTGACTGACAAGCATAAAAGGCTAACTTGTGG
ATAGTGTTTACAAAAGTACAAAAGTACTACTTCCAAGGAAAATGCTCTGATTCTCTGTTTAGGCATTTGTGAAGGATTCCAGAGCCTTTC
CCAAAGTGAGACCATTTCTGGGGTATTTGTACCAGGTCAGGGTTTTTGTGTTGTTTTCAAATAAGTTTGACTAAAATAAGTTTGGCTGAC
AGTTTTTGTATACCTGCTTTAATGTTTATAAAATTTTTATTGAGGTATAATTAAAATATAGTAAAATGCACAGAGGTTAAGTATTCTTAC
CTGCTTTAATTTTGAAACAGATTTTTATTGTCAAACAGAATTTGAAAGCATGTGTTTAACACATGGATATAATTTAGCTTTGTGTCACCT
TTGAATCTGAGGCAGTTTCCCAAACAAAAAGGCTGGAGCCATTTTTCAGAAGTTGCTTATACCCTGTTCCCAAACTATCAGCCTTGATTA
ATTTCTAGTAGGAAGAGAATAATTACATTTGCGGGGGGGGGGGTGGATAAAAAACATGTCTGCTTCTCATTTAAATAAGAGAGAAATGAT
GCCGTTTTTTAAATGTGAAGCAGACTATAATTCTCAGCTCTCTTTTCTTCTTAGCCTTAAATTAATATTCTCTTTCTTCTAGTTTTGGAA
AGTGTAGTGGGAATATTCAGACAAAAGAGGCCATTTTCCATTTTTAAAGCTTCTTACTGGTGAAACAGCCCAGTTGTAGTAGGTGCCAGT
CAGTCAAGGCAGGGGCCCTCTCTCCGTCAATATGGAAAACTCAGCAGTTTTCCTCTCCCCCAGTTGTGTTCTTGTAACGTTGTTAATGGG
TTCCTTTGCTTTTTGCTTTCTCCTTTTCTGAAAATGTATGTGTTTTGCCTCTCTTTTGGCTACATCTTCAAAATATTTCTTTTGTGCCTA
TGTACATGTGTAAACATGCCATAGCATGTGTGGTAGGTGTCCTGTATTTTGTTTGGGAAAAAAACTATCAAAATGAGGAAGAGAATTTCC
CCTATTTATGCACTAGGTTTCTGTGCTTTTTCTTTGAGTTCTCTGGAGTAGATATTAATTTGATACCTTCATGGTAATGAAATTATGATG
GAGCTGTGTTATAAATTCCTTATGTCAGAGGCCAGTGCGGTAGCCTTTGTCCCTTCATGCCTTTCAATTCTGAGTGGGAGGAAAAGCAAA
CATCAAAACAGTGCTTCAGCCAAATTCCATATGTAATGCCATTGGGAGAGTATTGACTAAAATATCATTCGTCAGGGAAATATAGTTGTA
ATATTTTTACAGGATATTCCTAGGTAAATGAAGGAGCCTTCAGTTGTAAATTTCAATTACCCCAAAATGTATTTGCTACATTTTGTTGTT
TGAAGTATTACCTCTTAACCTTCTTTGTTAATTTTTTTCATTTTGTCTTATATAGTCCAGTTTTCCAAGATAAGCTCAGTCCTTTTTCAA

>In-frame_ENST00000329236_ENST00000218343_TCGA-D8-A1JB-01A_RBM10_chrX_47028897_-_PHF16_chrX_46857522_length(amino acids)=954AA_start in transcript=61_stop in transcript=2925
MGVGGSEFPWEGSALGASPLPPICLQSRTWLLRAPAPAELGELEEVAAGRGDVWEPFLDSPGREESLQEASPRLADHGSSSGGGWEVKRS
QRLRRGPSSPRRPYQDMEYERRGGRGDRTGRYGATDRSQDDGGENRSRDHDYRDMDYRSYPREYGSQEGKHDYDDSSEEQSAEVFRKDLI
SAMKLPDSHHINPDSYYLFADTWKEEWEKGVQVPASPDTVPQPSLRIIAEKVKDVLFIRPRKYIHCSSPDTTEPGYINIMELAASVCRYD
LDDMDIFWLQELNEDLAEMGCGPVDENLMEKTVEVLERHCHENMNHAIETEEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQ
ACYGILKVPEGSWLCRSCVLGIYPQCVLCPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWALVCNLCKLKT
GACIQCSIKSCITAFHVTCAFEHGLEMKTILDEGDEVKFKSYCLKHSQNRQKLGEAEYPHHRAKEQSQAKSEKTSLRAQKLRELEEEFYS
LVRVEDVAAELGMPTLAVDFIYNYWKLKRKSNFNKPLFPPKEDEENGLVQPKEESIHTRMRMFMHLRQDLERVRNLCYMISRREKLKLSH
NKIQEQIFGLQVQLLNQEIDAGLPLTNALENSLFYPPPRITLKLKMPKSTPEDHRNSSTETDQQPHSPDSSSSVHSIRNMQVPQESLEMR
TKSYPRYPLESKNNRLLASLSHSRSEAKESSPAWRTPSSECYHGQSLGKPLVLQAALHGQSSIGNGKSQPNSKFAKSNGLEGSWSGNVTQ
KDSSSEMFCDQEPVFSPHLVSQGSFRKSTVEHFSRSFKETTNRWVKNTEDLQCYVKPTKNMSPKEQFWGRQVLRRSAGRAPYQENDGYCP

--------------------------------------------------------------
>In-frame_ENST00000345781_ENST00000397189_TCGA-D8-A1JB-01A_RBM10_chrX_47028897_-_PHF16_chrX_46857522_length(transcript)=5041nt_BP=533nt
GTGACTGTGGCCGGCTGGGAGTAGGCGGCAGTGAGTTTCCCTGGGAGGGCAGCGCGCTTGGCGCTTCTCCCCTCCCCCCGATCTGCCTCC
AGTCTCGGACTTGGTTGTTGCGCGCTCCGGCTCCGGCTGAGCTGGGAGAGTTGGAGGAGGTGGCGGCGGGCAGAGGTGATGTCTGGGAGC
CCTTCCTTGACAGCCCGGGCCGAGAAGAGTCCCTGCAGGAAGCATCACCCAGGCTGGCAGATCATGGTAGCAGCAGCGGGGGTGGCTGGG
AAGTGAAACGGAGCCAGCGGCTGAGGAGGGGCCCCAGCAGCCCCCGAAGGCCCTATCAGGACATGGAGTATGAAAGACGTGGTGGTCGTG
GTGACAGGACTGGCCGCTATGGAGCCACTGACCGCTCGCAGGATGATGGTGGGGAGAACCGCAGCCGAGACCACGACTACCGGGACATGG
ACTACCGTTCATATCCTCGCGAGTATGGCAGCCAGGAGGGCAAGCATGACTATGACGACTCATCTGAGGAGCAGAGTGCGGAGGTATTCC
GGAAGGACCTCATCAGTGCCATGAAACTTCCAGATTCTCACCACATTAATCCTGATAGCTATTACCTCTTTGCTGATACATGGAAGGAAG
AATGGGAAAAGGGAGTCCAGGTACCAGCCAGTCCAGACACCGTTCCACAGCCTTCTCTCAGGATTATAGCTGAGAAGGTAAAGGACGTTC
TGTTTATCCGACCCCGGAAGTATATTCACTGCTCCAGCCCAGACACCACAGAGCCTGGCTACATCAACATCATGGAGTTGGCAGCATCTG
TTTGCCGCTATGACCTAGATGACATGGACATCTTCTGGCTTCAGGAACTCAATGAAGACCTTGCAGAAATGGGTTGTGGGCCAGTTGATG
AGAATCTTATGGAAAAGACAGTAGAAGTCCTGGAACGCCATTGCCATGAAAATATGAACCATGCTATTGAGACAGAGGAAGGGCTAGGCA
TAGAGTATGATGAAGATGTGATCTGTGATGTGTGCCGGTCTCCAGACAGTGAAGAAGGGAATGATATGGTGTTCTGTGATAAGTGTAACG
TCTGTGTGCATCAGGCCTGCTATGGCATCCTCAAGGTCCCAGAAGGCAGCTGGCTGTGTCGCTCCTGTGTCCTGGGCATTTATCCGCAAT
GTGTGTTATGTCCAAAGAAAGGTGGAGCCCTGAAGACCACCAAGACAGGGACTAAATGGGCTCATGTCAGCTGTGCCCTGTGGATCCCAG
AGGTCAGCATTGCTTGTCCTGAGAGGATGGAACCGATCACGAAGATCTCCCACATCCCACCCAGTCGGTGGGCCTTAGTCTGCAACTTGT
GCAAGTTGAAGACGGGGGCTTGTATTCAGTGCTCTATAAAAAGCTGCATCACTGCCTTCCACGTCACCTGTGCCTTTGAGCACGGCCTAG
AGATGAAGACCATCCTAGATGAGGGAGACGAAGTGAAGTTCAAGTCATATTGCCTCAAGCATAGCCAAAACAGGCAGAAACTTGGAGAAG
CTGAGTACCCCCACCACAGGGCTAAAGAGCAGAGCCAGGCCAAAAGTGAGAAAACCAGCCTGCGGGCACAGAAGCTTCGGGAGCTGGAGG
AGGAGTTCTATTCCTTGGTACGAGTGGAAGATGTGGCCGCAGAGCTGGGTATGCCCACGCTAGCTGTGGACTTTATCTATAACTACTGGA
AACTGAAGCGGAAAAGTAACTTCAATAAGCCATTATTTCCTCCAAAGGAGGATGAAGAAAATGGGCTGGTGCAGCCAAAAGAGGAAAGCA
TTCACACTCGAATGAGAATGTTTATGCATCTACGCCAGGACCTGGAGAGGGTCCGAAATCTGTGCTATATGATAAGCAGACGAGAGAAGC
TGAAGCTGTCACACAACAAAATACAGGAACAGATCTTCGGTTTGCAAGTCCAGCTTCTTAACCAAGAAATTGATGCAGGGCTTCCTTTGA
CAAATGCACTTGAAAACTCACTGTTTTACCCACCACCAAGAATTACCTTGAAGTTAAAAATGCCCAAATCAACCCCAGAAGACCACAGAA
ACAGCTCCACAGAAACCGATCAGCAGCCCCACTCTCCTGACAGCAGCTCATCTGTTCACAGTATAAGGAACATGCAGGTGCCTCAGGAGT
CACTAGAAATGAGAACAAAATCGTATCCGAGATACCCACTAGAGAGCAAGAATAACCGTTTGCTGGCCAGTCTCAGCCATTCTAGGAGTG
AAGCAAAGGAGTCCAGTCCTGCTTGGAGAACCCCGTCCTCGGAGTGCTATCATGGGCAGTCACTGGGAAAGCCTCTGGTCCTTCAGGCTG
CCCTCCATGGACAGTCTTCCATTGGGAATGGGAAAAGTCAGCCTAACTCCAAGTTTGCCAAATCCAATGGCCTGGAGGGCAGCTGGTCTG
GGAATGTCACCCAAAAAGACAGCTCGAGTGAGATGTTCTGTGACCAGGAGCCTGTGTTCAGCCCCCACTTGGTCAGTCAGGGCAGCTTTA
GAAAATCCACTGTAGAACACTTTAGTAGGTCCTTTAAAGAGACCACCAATAGGTGGGTGAAGAACACAGAGGACCTCCAGTGCTATGTGA
AGCCAACCAAGAATATGAGCCCCAAGGAGCAGTTCTGGGGTAGACAGGTTCTCAGGCGGTCTGCAGGGAGAGCTCCATATCAGGAAAATG
ATGGCTATTGCCCAGATTTGGAGCTGAGTGATTCAGAGGCAGAAAGTGATGGGAATAAAGAAAAAGTCAGGGTAAGGAAAGATAGCTCAG
ACAGGGAAAATCCTCCCCATGACTCTAGACGGGATTGCCATGGTAAAAGCAAGACACATCCCCTTTCCCACAGTTCAATGCAAAGGTGAT
TAGAAACTTCCAAGGATGACCCAACCTTTGCCTTTGCCCCATATATTGGGGAAAACCCATACACCAAAAGGATTTTAGCATATGTTAAGA
GGAATTGCAGTGAAAAGGATAACATTTTTCCATAGTAAATTGTCTTGCAGTTTTTGAAAATGTTTCAAGTCTAGTTTTTACAAGCACATT
ACAGTAATTGCAGGTTGTCCAGAGGTTGGTTTGTCAGAGGCTATTGGGAACAGCTGGGCCCAGGGTATTTGCTCAGTAAATATTTTGGGG
CAGCTTTCCGGTTATATAACACATTGACAAGTATATGTATTAAGAGTCCTTGCATTGTTAACTGATTTGCAAGAGACCATGATTATCAGA
CACTAAAACTACTTATCTTTTGAAGCTACAGCATGTGACTCCCCAGAGCTCCTGTCTGTAGGAAGTTTCTAATTCCCTGGTATCTATAAA
CCCTTTTCAGGGGAGAGACCGGAGACCCCATCTTAGATACTGTCAACTCACTACTGTCTTCCTTTGTTCTGCACAAGGTTGAGTTTCTTT
CACAGTATCTTAACTTACTGAGTCAATACTCCTCATGCTTATCAGTGTCCAGTGCCTGTTCCTAAACTTGCTTGTTGGGGACACACTCAT
AACTATTTCACCTGACTGACAAGCATAAAAGGCTAACTTGTGGATAGTGTTTACAAAAGTACAAAAGTACTACTTCCAAGGAAAATGCTC
TGATTCTCTGTTTAGGCATTTGTGAAGGATTCCAGAGCCTTTCCCAAAGTGAGACCATTTCTGGGGTATTTGTACCAGGTCAGGGTTTTT
GTGTTGTTTTCAAATAAGTTTGACTAAAATAAGTTTGGCTGACAGTTTTTGTATACCTGCTTTAATGTTTATAAAATTTTTATTGAGGTA
TAATTAAAATATAGTAAAATGCACAGAGGTTAAGTATTCTTACCTGCTTTAATTTTGAAACAGATTTTTATTGTCAAACAGAATTTGAAA
GCATGTGTTTAACACATGGATATAATTTAGCTTTGTGTCACCTTTGAATCTGAGGCAGTTTCCCAAACAAAAAGGCTGGAGCCATTTTTC
AGAAGTTGCTTATACCCTGTTCCCAAACTATCAGCCTTGATTAATTTCTAGTAGGAAGAGAATAATTACATTTGCGGGGGGGGGGGTGGA
TAAAAAACATGTCTGCTTCTCATTTAAATAAGAGAGAAATGATGCCGTTTTTTAAATGTGAAGCAGACTATAATTCTCAGCTCTCTTTTC
TTCTTAGCCTTAAATTAATATTCTCTTTCTTCTAGTTTTGGAAAGTGTAGTGGGAATATTCAGACAAAAGAGGCCATTTTCCATTTTTAA
AGCTTCTTACTGGTGAAACAGCCCAGTTGTAGTAGGTGCCAGTCAGTCAAGGCAGGGGCCCTCTCTCCGTCAATATGGAAAACTCAGCAG
TTTTCCTCTCCCCCAGTTGTGTTCTTGTAACGTTGTTAATGGGTTCCTTTGCTTTTTGCTTTCTCCTTTTCTGAAAATGTATGTGTTTTG
CCTCTCTTTTGGCTACATCTTCAAAATATTTCTTTTGTGCCTATGTACATGTGTAAACATGCCATAGCATGTGTGGTAGGTGTCCTGTAT
TTTGTTTGGGAAAAAAACTATCAAAATGAGGAAGAGAATTTCCCCTATTTATGCACTAGGTTTCTGTGCTTTTTCTTTGAGTTCTCTGGA
GTAGATATTAATTTGATACCTTCATGGTAATGAAATTATGATGGAGCTGTGTTATAAATTCCTTATGTCAGAGGCCAGTGCGGTAGCCTT
TGTCCCTTCATGCCTTTCAATTCTGAGTGGGAGGAAAAGCAAACATCAAAACAGTGCTTCAGCCAAATTCCATATGTAATGCCATTGGGA
GAGTATTGACTAAAATATCATTCGTCAGGGAAATATAGTTGTAATATTTTTACAGGATATTCCTAGGTAAATGAAGGAGCCTTCAGTTGT
AAATTTCAATTACCCCAAAATGTATTTGCTACATTTTGTTGTTTGAAGTATTACCTCTTAACCTTCTTTGTTAATTTTTTTCATTTTGTC
TTATATAGTCCAGTTTTCCAAGATAAGCTCAGTCCTTTTTCAAATGTCCCCTTTTTACCAATACTTTTTCATTAAATTATGAAAACTGCT

>In-frame_ENST00000345781_ENST00000397189_TCGA-D8-A1JB-01A_RBM10_chrX_47028897_-_PHF16_chrX_46857522_length(amino acids)=954AA_start in transcript=14_stop in transcript=2878
MGVGGSEFPWEGSALGASPLPPICLQSRTWLLRAPAPAELGELEEVAAGRGDVWEPFLDSPGREESLQEASPRLADHGSSSGGGWEVKRS
QRLRRGPSSPRRPYQDMEYERRGGRGDRTGRYGATDRSQDDGGENRSRDHDYRDMDYRSYPREYGSQEGKHDYDDSSEEQSAEVFRKDLI
SAMKLPDSHHINPDSYYLFADTWKEEWEKGVQVPASPDTVPQPSLRIIAEKVKDVLFIRPRKYIHCSSPDTTEPGYINIMELAASVCRYD
LDDMDIFWLQELNEDLAEMGCGPVDENLMEKTVEVLERHCHENMNHAIETEEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQ
ACYGILKVPEGSWLCRSCVLGIYPQCVLCPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWALVCNLCKLKT
GACIQCSIKSCITAFHVTCAFEHGLEMKTILDEGDEVKFKSYCLKHSQNRQKLGEAEYPHHRAKEQSQAKSEKTSLRAQKLRELEEEFYS
LVRVEDVAAELGMPTLAVDFIYNYWKLKRKSNFNKPLFPPKEDEENGLVQPKEESIHTRMRMFMHLRQDLERVRNLCYMISRREKLKLSH
NKIQEQIFGLQVQLLNQEIDAGLPLTNALENSLFYPPPRITLKLKMPKSTPEDHRNSSTETDQQPHSPDSSSSVHSIRNMQVPQESLEMR
TKSYPRYPLESKNNRLLASLSHSRSEAKESSPAWRTPSSECYHGQSLGKPLVLQAALHGQSSIGNGKSQPNSKFAKSNGLEGSWSGNVTQ
KDSSSEMFCDQEPVFSPHLVSQGSFRKSTVEHFSRSFKETTNRWVKNTEDLQCYVKPTKNMSPKEQFWGRQVLRRSAGRAPYQENDGYCP

--------------------------------------------------------------
>In-frame_ENST00000345781_ENST00000218343_TCGA-D8-A1JB-01A_RBM10_chrX_47028897_-_PHF16_chrX_46857522_length(transcript)=5040nt_BP=533nt
GTGACTGTGGCCGGCTGGGAGTAGGCGGCAGTGAGTTTCCCTGGGAGGGCAGCGCGCTTGGCGCTTCTCCCCTCCCCCCGATCTGCCTCC
AGTCTCGGACTTGGTTGTTGCGCGCTCCGGCTCCGGCTGAGCTGGGAGAGTTGGAGGAGGTGGCGGCGGGCAGAGGTGATGTCTGGGAGC
CCTTCCTTGACAGCCCGGGCCGAGAAGAGTCCCTGCAGGAAGCATCACCCAGGCTGGCAGATCATGGTAGCAGCAGCGGGGGTGGCTGGG
AAGTGAAACGGAGCCAGCGGCTGAGGAGGGGCCCCAGCAGCCCCCGAAGGCCCTATCAGGACATGGAGTATGAAAGACGTGGTGGTCGTG
GTGACAGGACTGGCCGCTATGGAGCCACTGACCGCTCGCAGGATGATGGTGGGGAGAACCGCAGCCGAGACCACGACTACCGGGACATGG
ACTACCGTTCATATCCTCGCGAGTATGGCAGCCAGGAGGGCAAGCATGACTATGACGACTCATCTGAGGAGCAGAGTGCGGAGGTATTCC
GGAAGGACCTCATCAGTGCCATGAAACTTCCAGATTCTCACCACATTAATCCTGATAGCTATTACCTCTTTGCTGATACATGGAAGGAAG
AATGGGAAAAGGGAGTCCAGGTACCAGCCAGTCCAGACACCGTTCCACAGCCTTCTCTCAGGATTATAGCTGAGAAGGTAAAGGACGTTC
TGTTTATCCGACCCCGGAAGTATATTCACTGCTCCAGCCCAGACACCACAGAGCCTGGCTACATCAACATCATGGAGTTGGCAGCATCTG
TTTGCCGCTATGACCTAGATGACATGGACATCTTCTGGCTTCAGGAACTCAATGAAGACCTTGCAGAAATGGGTTGTGGGCCAGTTGATG
AGAATCTTATGGAAAAGACAGTAGAAGTCCTGGAACGCCATTGCCATGAAAATATGAACCATGCTATTGAGACAGAGGAAGGGCTAGGCA
TAGAGTATGATGAAGATGTGATCTGTGATGTGTGCCGGTCTCCAGACAGTGAAGAAGGGAATGATATGGTGTTCTGTGATAAGTGTAACG
TCTGTGTGCATCAGGCCTGCTATGGCATCCTCAAGGTCCCAGAAGGCAGCTGGCTGTGTCGCTCCTGTGTCCTGGGCATTTATCCGCAAT
GTGTGTTATGTCCAAAGAAAGGTGGAGCCCTGAAGACCACCAAGACAGGGACTAAATGGGCTCATGTCAGCTGTGCCCTGTGGATCCCAG
AGGTCAGCATTGCTTGTCCTGAGAGGATGGAACCGATCACGAAGATCTCCCACATCCCACCCAGTCGGTGGGCCTTAGTCTGCAACTTGT
GCAAGTTGAAGACGGGGGCTTGTATTCAGTGCTCTATAAAAAGCTGCATCACTGCCTTCCACGTCACCTGTGCCTTTGAGCACGGCCTAG
AGATGAAGACCATCCTAGATGAGGGAGACGAAGTGAAGTTCAAGTCATATTGCCTCAAGCATAGCCAAAACAGGCAGAAACTTGGAGAAG
CTGAGTACCCCCACCACAGGGCTAAAGAGCAGAGCCAGGCCAAAAGTGAGAAAACCAGCCTGCGGGCACAGAAGCTTCGGGAGCTGGAGG
AGGAGTTCTATTCCTTGGTACGAGTGGAAGATGTGGCCGCAGAGCTGGGTATGCCCACGCTAGCTGTGGACTTTATCTATAACTACTGGA
AACTGAAGCGGAAAAGTAACTTCAATAAGCCATTATTTCCTCCAAAGGAGGATGAAGAAAATGGGCTGGTGCAGCCAAAAGAGGAAAGCA
TTCACACTCGAATGAGAATGTTTATGCATCTACGCCAGGACCTGGAGAGGGTCCGAAATCTGTGCTATATGATAAGCAGACGAGAGAAGC
TGAAGCTGTCACACAACAAAATACAGGAACAGATCTTCGGTTTGCAAGTCCAGCTTCTTAACCAAGAAATTGATGCAGGGCTTCCTTTGA
CAAATGCACTTGAAAACTCACTGTTTTACCCACCACCAAGAATTACCTTGAAGTTAAAAATGCCCAAATCAACCCCAGAAGACCACAGAA
ACAGCTCCACAGAAACCGATCAGCAGCCCCACTCTCCTGACAGCAGCTCATCTGTTCACAGTATAAGGAACATGCAGGTGCCTCAGGAGT
CACTAGAAATGAGAACAAAATCGTATCCGAGATACCCACTAGAGAGCAAGAATAACCGTTTGCTGGCCAGTCTCAGCCATTCTAGGAGTG
AAGCAAAGGAGTCCAGTCCTGCTTGGAGAACCCCGTCCTCGGAGTGCTATCATGGGCAGTCACTGGGAAAGCCTCTGGTCCTTCAGGCTG
CCCTCCATGGACAGTCTTCCATTGGGAATGGGAAAAGTCAGCCTAACTCCAAGTTTGCCAAATCCAATGGCCTGGAGGGCAGCTGGTCTG
GGAATGTCACCCAAAAAGACAGCTCGAGTGAGATGTTCTGTGACCAGGAGCCTGTGTTCAGCCCCCACTTGGTCAGTCAGGGCAGCTTTA
GAAAATCCACTGTAGAACACTTTAGTAGGTCCTTTAAAGAGACCACCAATAGGTGGGTGAAGAACACAGAGGACCTCCAGTGCTATGTGA
AGCCAACCAAGAATATGAGCCCCAAGGAGCAGTTCTGGGGTAGACAGGTTCTCAGGCGGTCTGCAGGGAGAGCTCCATATCAGGAAAATG
ATGGCTATTGCCCAGATTTGGAGCTGAGTGATTCAGAGGCAGAAAGTGATGGGAATAAAGAAAAAGTCAGGGTAAGGAAAGATAGCTCAG
ACAGGGAAAATCCTCCCCATGACTCTAGACGGGATTGCCATGGTAAAAGCAAGACACATCCCCTTTCCCACAGTTCAATGCAAAGGTGAT
TAGAAACTTCCAAGGATGACCCAACCTTTGCCTTTGCCCCATATATTGGGGAAAACCCATACACCAAAAGGATTTTAGCATATGTTAAGA
GGAATTGCAGTGAAAAGGATAACATTTTTCCATAGTAAATTGTCTTGCAGTTTTTGAAAATGTTTCAAGTCTAGTTTTTACAAGCACATT
ACAGTAATTGCAGGTTGTCCAGAGGTTGGTTTGTCAGAGGCTATTGGGAACAGCTGGGCCCAGGGTATTTGCTCAGTAAATATTTTGGGG
CAGCTTTCCGGTTATATAACACATTGACAAGTATATGTATTAAGAGTCCTTGCATTGTTAACTGATTTGCAAGAGACCATGATTATCAGA
CACTAAAACTACTTATCTTTTGAAGCTACAGCATGTGACTCCCCAGAGCTCCTGTCTGTAGGAAGTTTCTAATTCCCTGGTATCTATAAA
CCCTTTTCAGGGGAGAGACCGGAGACCCCATCTTAGATACTGTCAACTCACTACTGTCTTCCTTTGTTCTGCACAAGGTTGAGTTTCTTT
CACAGTATCTTAACTTACTGAGTCAATACTCCTCATGCTTATCAGTGTCCAGTGCCTGTTCCTAAACTTGCTTGTTGGGGACACACTCAT
AACTATTTCACCTGACTGACAAGCATAAAAGGCTAACTTGTGGATAGTGTTTACAAAAGTACAAAAGTACTACTTCCAAGGAAAATGCTC
TGATTCTCTGTTTAGGCATTTGTGAAGGATTCCAGAGCCTTTCCCAAAGTGAGACCATTTCTGGGGTATTTGTACCAGGTCAGGGTTTTT
GTGTTGTTTTCAAATAAGTTTGACTAAAATAAGTTTGGCTGACAGTTTTTGTATACCTGCTTTAATGTTTATAAAATTTTTATTGAGGTA
TAATTAAAATATAGTAAAATGCACAGAGGTTAAGTATTCTTACCTGCTTTAATTTTGAAACAGATTTTTATTGTCAAACAGAATTTGAAA
GCATGTGTTTAACACATGGATATAATTTAGCTTTGTGTCACCTTTGAATCTGAGGCAGTTTCCCAAACAAAAAGGCTGGAGCCATTTTTC
AGAAGTTGCTTATACCCTGTTCCCAAACTATCAGCCTTGATTAATTTCTAGTAGGAAGAGAATAATTACATTTGCGGGGGGGGGGGTGGA
TAAAAAACATGTCTGCTTCTCATTTAAATAAGAGAGAAATGATGCCGTTTTTTAAATGTGAAGCAGACTATAATTCTCAGCTCTCTTTTC
TTCTTAGCCTTAAATTAATATTCTCTTTCTTCTAGTTTTGGAAAGTGTAGTGGGAATATTCAGACAAAAGAGGCCATTTTCCATTTTTAA
AGCTTCTTACTGGTGAAACAGCCCAGTTGTAGTAGGTGCCAGTCAGTCAAGGCAGGGGCCCTCTCTCCGTCAATATGGAAAACTCAGCAG
TTTTCCTCTCCCCCAGTTGTGTTCTTGTAACGTTGTTAATGGGTTCCTTTGCTTTTTGCTTTCTCCTTTTCTGAAAATGTATGTGTTTTG
CCTCTCTTTTGGCTACATCTTCAAAATATTTCTTTTGTGCCTATGTACATGTGTAAACATGCCATAGCATGTGTGGTAGGTGTCCTGTAT
TTTGTTTGGGAAAAAAACTATCAAAATGAGGAAGAGAATTTCCCCTATTTATGCACTAGGTTTCTGTGCTTTTTCTTTGAGTTCTCTGGA
GTAGATATTAATTTGATACCTTCATGGTAATGAAATTATGATGGAGCTGTGTTATAAATTCCTTATGTCAGAGGCCAGTGCGGTAGCCTT
TGTCCCTTCATGCCTTTCAATTCTGAGTGGGAGGAAAAGCAAACATCAAAACAGTGCTTCAGCCAAATTCCATATGTAATGCCATTGGGA
GAGTATTGACTAAAATATCATTCGTCAGGGAAATATAGTTGTAATATTTTTACAGGATATTCCTAGGTAAATGAAGGAGCCTTCAGTTGT
AAATTTCAATTACCCCAAAATGTATTTGCTACATTTTGTTGTTTGAAGTATTACCTCTTAACCTTCTTTGTTAATTTTTTTCATTTTGTC
TTATATAGTCCAGTTTTCCAAGATAAGCTCAGTCCTTTTTCAAATGTCCCCTTTTTACCAATACTTTTTCATTAAATTATGAAAACTGCT

>In-frame_ENST00000345781_ENST00000218343_TCGA-D8-A1JB-01A_RBM10_chrX_47028897_-_PHF16_chrX_46857522_length(amino acids)=954AA_start in transcript=14_stop in transcript=2878
MGVGGSEFPWEGSALGASPLPPICLQSRTWLLRAPAPAELGELEEVAAGRGDVWEPFLDSPGREESLQEASPRLADHGSSSGGGWEVKRS
QRLRRGPSSPRRPYQDMEYERRGGRGDRTGRYGATDRSQDDGGENRSRDHDYRDMDYRSYPREYGSQEGKHDYDDSSEEQSAEVFRKDLI
SAMKLPDSHHINPDSYYLFADTWKEEWEKGVQVPASPDTVPQPSLRIIAEKVKDVLFIRPRKYIHCSSPDTTEPGYINIMELAASVCRYD
LDDMDIFWLQELNEDLAEMGCGPVDENLMEKTVEVLERHCHENMNHAIETEEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQ
ACYGILKVPEGSWLCRSCVLGIYPQCVLCPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWALVCNLCKLKT
GACIQCSIKSCITAFHVTCAFEHGLEMKTILDEGDEVKFKSYCLKHSQNRQKLGEAEYPHHRAKEQSQAKSEKTSLRAQKLRELEEEFYS
LVRVEDVAAELGMPTLAVDFIYNYWKLKRKSNFNKPLFPPKEDEENGLVQPKEESIHTRMRMFMHLRQDLERVRNLCYMISRREKLKLSH
NKIQEQIFGLQVQLLNQEIDAGLPLTNALENSLFYPPPRITLKLKMPKSTPEDHRNSSTETDQQPHSPDSSSSVHSIRNMQVPQESLEMR
TKSYPRYPLESKNNRLLASLSHSRSEAKESSPAWRTPSSECYHGQSLGKPLVLQAALHGQSSIGNGKSQPNSKFAKSNGLEGSWSGNVTQ
KDSSSEMFCDQEPVFSPHLVSQGSFRKSTVEHFSRSFKETTNRWVKNTEDLQCYVKPTKNMSPKEQFWGRQVLRRSAGRAPYQENDGYCP

--------------------------------------------------------------

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Fusion Gene PPI Analysis for RBM10-PHF16


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RBM10-PHF16


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for RBM10-PHF16


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneRBM10C1839463TARP syndrome4CTD_human;GENOMICS_ENGLAND;ORPHANET
HgeneRBM10C0008925Cleft Palate1GENOMICS_ENGLAND
HgeneRBM10C0152427Polydactyly1GENOMICS_ENGLAND