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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:RBM26-ATG5 (FusionGDB2 ID:72374)

Fusion Gene Summary for RBM26-ATG5

check button Fusion gene summary
Fusion gene informationFusion gene name: RBM26-ATG5
Fusion gene ID: 72374
HgeneTgene
Gene symbol

RBM26

ATG5

Gene ID

64062

9474

Gene nameRNA binding motif protein 26autophagy related 5
SynonymsARRS2|C13orf10|PPP1R132|PRO1777|SE70-2|ZC3H17APG5|APG5-LIKE|APG5L|ASP|SCAR25|hAPG5
Cytomap

13q31.1

6q21

Type of geneprotein-codingprotein-coding
DescriptionRNA-binding protein 26CTCL tumor antigen se70-2acidic rich RS domain containing 2cutaneous T-cell lymphoma tumor antigen se70-2protein phosphatase 1, regulatory 132autophagy protein 5APG5 autophagy 5-likeATG5 autophagy related 5 homologapoptosis-specific protein
Modification date2020031320200313
UniProtAcc.

Q9H1Y0

Ensembl transtripts involved in fusion geneENST00000267229, ENST00000438737, 
ENST00000438724, ENST00000461008, 
ENST00000343245, ENST00000369070, 
ENST00000369076, ENST00000360666, 
ENST00000475645, 
Fusion gene scores* DoF score3 X 3 X 2=1815 X 12 X 7=1260
# samples 315
** MAII scorelog2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(15/1260*10)=-3.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RBM26 [Title/Abstract] AND ATG5 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRBM26(79979838)-ATG5(106649964), # samples:1
Anticipated loss of major functional domain due to fusion event.RBM26-ATG5 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneRBM26

GO:0010923

negative regulation of phosphatase activity

19389623


check buttonFusion gene breakpoints across RBM26 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across ATG5 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-59-2354RBM26chr13

79979838

-ATG5chr6

106649964

-


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Fusion Gene ORF analysis for RBM26-ATG5

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000267229ENST00000343245RBM26chr13

79979838

-ATG5chr6

106649964

-
In-frameENST00000267229ENST00000369070RBM26chr13

79979838

-ATG5chr6

106649964

-
In-frameENST00000267229ENST00000369076RBM26chr13

79979838

-ATG5chr6

106649964

-
Frame-shiftENST00000267229ENST00000360666RBM26chr13

79979838

-ATG5chr6

106649964

-
5CDS-5UTRENST00000267229ENST00000475645RBM26chr13

79979838

-ATG5chr6

106649964

-
In-frameENST00000438737ENST00000343245RBM26chr13

79979838

-ATG5chr6

106649964

-
In-frameENST00000438737ENST00000369070RBM26chr13

79979838

-ATG5chr6

106649964

-
In-frameENST00000438737ENST00000369076RBM26chr13

79979838

-ATG5chr6

106649964

-
Frame-shiftENST00000438737ENST00000360666RBM26chr13

79979838

-ATG5chr6

106649964

-
5CDS-5UTRENST00000438737ENST00000475645RBM26chr13

79979838

-ATG5chr6

106649964

-
In-frameENST00000438724ENST00000343245RBM26chr13

79979838

-ATG5chr6

106649964

-
In-frameENST00000438724ENST00000369070RBM26chr13

79979838

-ATG5chr6

106649964

-
In-frameENST00000438724ENST00000369076RBM26chr13

79979838

-ATG5chr6

106649964

-
Frame-shiftENST00000438724ENST00000360666RBM26chr13

79979838

-ATG5chr6

106649964

-
5CDS-5UTRENST00000438724ENST00000475645RBM26chr13

79979838

-ATG5chr6

106649964

-
intron-3CDSENST00000461008ENST00000343245RBM26chr13

79979838

-ATG5chr6

106649964

-
intron-3CDSENST00000461008ENST00000369070RBM26chr13

79979838

-ATG5chr6

106649964

-
intron-3CDSENST00000461008ENST00000369076RBM26chr13

79979838

-ATG5chr6

106649964

-
intron-3CDSENST00000461008ENST00000360666RBM26chr13

79979838

-ATG5chr6

106649964

-
intron-5UTRENST00000461008ENST00000475645RBM26chr13

79979838

-ATG5chr6

106649964

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000267229RBM26chr1379979838-ENST00000343245ATG5chr6106649964-240485945123897
ENST00000267229RBM26chr1379979838-ENST00000369070ATG5chr6106649964-240485945123897
ENST00000267229RBM26chr1379979838-ENST00000369076ATG5chr6106649964-240485945123897
ENST00000438737RBM26chr1379979838-ENST00000343245ATG5chr6106649964-283151257162169
ENST00000438737RBM26chr1379979838-ENST00000369070ATG5chr6106649964-283151257162169
ENST00000438737RBM26chr1379979838-ENST00000369076ATG5chr6106649964-283151257162169
ENST00000438724RBM26chr1379979838-ENST00000343245ATG5chr6106649964-2446127987128097
ENST00000438724RBM26chr1379979838-ENST00000369070ATG5chr6106649964-2446127987128097
ENST00000438724RBM26chr1379979838-ENST00000369076ATG5chr6106649964-2446127987128097

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000267229ENST00000343245RBM26chr1379979838-ATG5chr6106649964-0.876848760.12315126
ENST00000267229ENST00000369070RBM26chr1379979838-ATG5chr6106649964-0.876848760.12315126
ENST00000267229ENST00000369076RBM26chr1379979838-ATG5chr6106649964-0.876848760.12315126
ENST00000438737ENST00000343245RBM26chr1379979838-ATG5chr6106649964-0.89702470.10297533
ENST00000438737ENST00000369070RBM26chr1379979838-ATG5chr6106649964-0.89702470.10297533
ENST00000438737ENST00000369076RBM26chr1379979838-ATG5chr6106649964-0.89702470.10297533
ENST00000438724ENST00000343245RBM26chr1379979838-ATG5chr6106649964-0.73728190.26271805
ENST00000438724ENST00000369070RBM26chr1379979838-ATG5chr6106649964-0.73728190.26271805
ENST00000438724ENST00000369076RBM26chr1379979838-ATG5chr6106649964-0.73728190.26271805

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Fusion Genomic Features for RBM26-ATG5


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for RBM26-ATG5


check button Go to

FGviewer for the breakpoints of chr13:79979838-chr6:106649964

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ATG5

Q9H1Y0

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. Involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocyte differentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT20 via the autophagic pathway. {ECO:0000250|UniProtKB:Q99J83, ECO:0000269|PubMed:12207896, ECO:0000269|PubMed:20580051, ECO:0000269|PubMed:22170153, ECO:0000269|PubMed:26812546}.; FUNCTION: May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD. {ECO:0000269|PubMed:15778222, ECO:0000269|PubMed:7796880}.; FUNCTION: (Microbial infection) May act as a proviral factor. In association with ATG12, negatively regulates the innate antiviral immune response by impairing the type I IFN production pathway upon vesicular stomatitis virus (VSV) infection (PubMed:17709747). Required for the translation of incoming hepatitis C virus (HCV) RNA and, thereby, for initiation of HCV replication, but not required once infection is established (PubMed:19666601). {ECO:0000269|PubMed:17709747, ECO:0000269|PubMed:19666601}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRBM26chr13:79979838chr6:106649964ENST00000267229-121719_79523.666666666666668981.0Coiled coilOntology_term=ECO:0000255
HgeneRBM26chr13:79979838chr6:106649964ENST00000267229-121823_84723.666666666666668981.0Coiled coilOntology_term=ECO:0000255
HgeneRBM26chr13:79979838chr6:106649964ENST00000438724-121719_79523.666666666666668984.0Coiled coilOntology_term=ECO:0000255
HgeneRBM26chr13:79979838chr6:106649964ENST00000438724-121823_84723.666666666666668984.0Coiled coilOntology_term=ECO:0000255
HgeneRBM26chr13:79979838chr6:106649964ENST00000438737-122719_79523.6666666666666681008.0Coiled coilOntology_term=ECO:0000255
HgeneRBM26chr13:79979838chr6:106649964ENST00000438737-122823_84723.6666666666666681008.0Coiled coilOntology_term=ECO:0000255
HgeneRBM26chr13:79979838chr6:106649964ENST00000267229-121134_21323.666666666666668981.0Compositional biasNote=Arg-rich
HgeneRBM26chr13:79979838chr6:106649964ENST00000267229-121326_42023.666666666666668981.0Compositional biasNote=Pro-rich
HgeneRBM26chr13:79979838chr6:106649964ENST00000438724-121134_21323.666666666666668984.0Compositional biasNote=Arg-rich
HgeneRBM26chr13:79979838chr6:106649964ENST00000438724-121326_42023.666666666666668984.0Compositional biasNote=Pro-rich
HgeneRBM26chr13:79979838chr6:106649964ENST00000438737-122134_21323.6666666666666681008.0Compositional biasNote=Arg-rich
HgeneRBM26chr13:79979838chr6:106649964ENST00000438737-122326_42023.6666666666666681008.0Compositional biasNote=Pro-rich
HgeneRBM26chr13:79979838chr6:106649964ENST00000267229-121532_60623.666666666666668981.0DomainRRM 1
HgeneRBM26chr13:79979838chr6:106649964ENST00000267229-121891_96023.666666666666668981.0DomainRRM 2
HgeneRBM26chr13:79979838chr6:106649964ENST00000438724-121532_60623.666666666666668984.0DomainRRM 1
HgeneRBM26chr13:79979838chr6:106649964ENST00000438724-121891_96023.666666666666668984.0DomainRRM 2
HgeneRBM26chr13:79979838chr6:106649964ENST00000438737-122532_60623.6666666666666681008.0DomainRRM 1
HgeneRBM26chr13:79979838chr6:106649964ENST00000438737-122891_96023.6666666666666681008.0DomainRRM 2
HgeneRBM26chr13:79979838chr6:106649964ENST00000267229-121288_31623.666666666666668981.0Zinc fingerC3H1-type
HgeneRBM26chr13:79979838chr6:106649964ENST00000438724-121288_31623.666666666666668984.0Zinc fingerC3H1-type
HgeneRBM26chr13:79979838chr6:106649964ENST00000438737-122288_31623.6666666666666681008.0Zinc fingerC3H1-type


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Fusion Gene Sequence for RBM26-ATG5


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000267229_ENST00000343245_TCGA-59-2354_RBM26_chr13_79979838_-_ATG5_chr6_106649964_length(transcript)=2404nt_BP=85nt
TAGGGCCGCTGTGGATGGTTTCTAAAATGATCATTGAAAACTTCGAGGCACTCAAGTCCTGGCTCAGCAAGACTCTCGAGCCCATACAAC
GACTGAAAGACCTTTCATTCAGAAGCTGTTTCGTCCTGTGGCTGCAGATGGACAGTTGCACACACTAGGAGATCTCCTCAAAGAAGTTTG
TCCTTCTGCTATTGATCCTGAAGATGGGGAAAAAAAGAATCAAGTGATGATTCATGGAATTGAGCCAATGTTGGAAACACCTCTGCAGTG
GCTGAGTGAACATCTGAGCTACCCGGATAATTTTCTTCATATTAGTATCATCCCACAGCCAACAGATTGAAGGATCAACTATTTGCCTGA
ACAGAATCATCCTTAAATGGGATTTATCAGAGCATGTCACCCTTTTGCTTCAATCAGGTTTGGTGGAGGCAACCTGACCAGAAACACTTC
GCTGCTGCAAGCCAGACAGGAAAAAGATTCCATGTCAGATAAGGCAACTGGGCTGGTCTTACTTTGCATCACCTCTGCTTTCCTCCACTG
CCATCATTAAACCTCAGCTGTGACATGAAAGACTTACCGGACCACTGAAGGTCTTCTGTAAAATATAATGAAGCTGAAACCTTTGGCCTA
AGAAGAAAATGGAAGTATGTGCCACTCGATTTGTATTTCTGATTAACAAATAAACAGGGGTATTTCCTAAGGTGACCATGGTTGAACTTT
AGCTCATGAAAGTGGAAACATTGGTTTAATTTTCAAGAGAATTAAGAAAGTAAAAGAGAAATTCTGTTATCAATAACTTGCAAGTAATTT
TTTGTAAAAGATTGAATTACAGTAAACCCATCTTTCCTTAACGAAAATTTCCTATGTTTACAGTCTGTCTATTGGTATGCAATCTTGTAA
CTTTGATAATGAACAGTGAGAGATTTTTAAATAAAGCCTCTAAATATGTTTTGTCATTTAATAACATACAGTTTTGTCACTTTTCAAGTA
CTTTCTGACTCACATACAGTAGATCACTTTTTACTCTGTGTTACCATTTTGACTGGTCGTCATTGGCATGGGGTGGATATAGGGCATAGG
ATTACTTGTCTCAGAAGCTGTCATAGAATTTCTTGCTGCCAATTAAAAAACCTGTGTTCTTTACACACTACACGTATAAATATTGTAACT
GTTCATCTTTGTTGTTTTATCACTGTAAGCCTGTCAAATCATAGTATCCTAAGCATCTGTAAATGCTAATTTTGCATTTTTGGAAAAACC
CATTCCTTCCAAGCTAGTGTTTTTCATTGGCTCCAGGTCTAATTTTTCACTGTGGTCCCTGGCAGCCAGTCTTTTGAAGTTTAAAGATTA
CCTGTCTCTTGACTGCAGTACCTTTTCTTTAATTTTTACCAAAAATATCCAGAGGTTACTGGAGTTCTTATTCAATATAAGGAAAGTTTG
CTGCACTTTATTACCAAGCCTCTGGGATTTTACCAGTCAAACATATTTGTGCATTACATTTCATTTCTTGTGAGCTAGCTGGCTGTCCAT
ATTGAATGTTGACCCATTTGAGTACGCTAAAAGGCTTACAGTATCAGACACGATCATGGTTTTAGATCCCATAATAAAAATGAATGTTTT
TCTTATAAAAAATTATACAAATGCTGAAGTGAGATTCTACTATTGTTCATTGCTTCCTTTTCTTTTTCCTTTTGCGATTTTCACTGATTA
ATAGCACATTTCTTCACAAAATTAGATAAAGTTGGTCAAAGACCAGATATTCTGGAATGGAAATTGTAAAGCTTAATCAAAAAGAATAGC
CAGTACAGCATACAATCTCAGAAACTTAGAAGCAAGTAGAAAATAATTGGTTGATGTAAACGAAAGTGCCATTTTAGTAAAGGCAGGAAA
AAAATAGCAATATTTGAGTTATGTAAGGATAAAAAATCCACTGACTTGTATTTTTGCACAAGAGGCTGGTCTGAATATGATTGTTCACAT
TAAGAGTGTTTATTCGTCGGTTCATTTTGGGGATTTTCCCCCTTGATGTTTTGACAGATTGAAGTGAGCTTTAGTGAGCAAAAGGATCAG
AATGCAGGGAACACTAAGCTGTGATGAAGAAAGTGTGGTAAAAAGCCAGAGTAGTTTTATACAGACAAAACCAGTGTCAGGCCTTTGCAG
TAGGCTTGAGTGAACTTCTGATCTAGATTTGAAAGTAAATTTTATGAAGACATTGCCCATTTTTACTTCCTCATTCATTATTGTACCAGC
ATCATAGCTTTATTACTCTAATCCCAGGTAAGTCAAGCCTACAATGCCCTAGAGGAAGAGTAAAACCAGAAATTCATGCTGGCTTAAATA

>In-frame_ENST00000267229_ENST00000343245_TCGA-59-2354_RBM26_chr13_79979838_-_ATG5_chr6_106649964_length(amino acids)=97AA_start in transcript=945_stop in transcript=1238
MFCHLITYSFVTFQVLSDSHTVDHFLLCVTILTGRHWHGVDIGHRITCLRSCHRISCCQLKNLCSLHTTRINIVTVHLCCFITVSLSNHS

--------------------------------------------------------------
>In-frame_ENST00000267229_ENST00000369070_TCGA-59-2354_RBM26_chr13_79979838_-_ATG5_chr6_106649964_length(transcript)=2404nt_BP=85nt
TAGGGCCGCTGTGGATGGTTTCTAAAATGATCATTGAAAACTTCGAGGCACTCAAGTCCTGGCTCAGCAAGACTCTCGAGCCCATACAAC
GACTGAAAGACCTTTCATTCAGAAGCTGTTTCGTCCTGTGGCTGCAGATGGACAGTTGCACACACTAGGAGATCTCCTCAAAGAAGTTTG
TCCTTCTGCTATTGATCCTGAAGATGGGGAAAAAAAGAATCAAGTGATGATTCATGGAATTGAGCCAATGTTGGAAACACCTCTGCAGTG
GCTGAGTGAACATCTGAGCTACCCGGATAATTTTCTTCATATTAGTATCATCCCACAGCCAACAGATTGAAGGATCAACTATTTGCCTGA
ACAGAATCATCCTTAAATGGGATTTATCAGAGCATGTCACCCTTTTGCTTCAATCAGGTTTGGTGGAGGCAACCTGACCAGAAACACTTC
GCTGCTGCAAGCCAGACAGGAAAAAGATTCCATGTCAGATAAGGCAACTGGGCTGGTCTTACTTTGCATCACCTCTGCTTTCCTCCACTG
CCATCATTAAACCTCAGCTGTGACATGAAAGACTTACCGGACCACTGAAGGTCTTCTGTAAAATATAATGAAGCTGAAACCTTTGGCCTA
AGAAGAAAATGGAAGTATGTGCCACTCGATTTGTATTTCTGATTAACAAATAAACAGGGGTATTTCCTAAGGTGACCATGGTTGAACTTT
AGCTCATGAAAGTGGAAACATTGGTTTAATTTTCAAGAGAATTAAGAAAGTAAAAGAGAAATTCTGTTATCAATAACTTGCAAGTAATTT
TTTGTAAAAGATTGAATTACAGTAAACCCATCTTTCCTTAACGAAAATTTCCTATGTTTACAGTCTGTCTATTGGTATGCAATCTTGTAA
CTTTGATAATGAACAGTGAGAGATTTTTAAATAAAGCCTCTAAATATGTTTTGTCATTTAATAACATACAGTTTTGTCACTTTTCAAGTA
CTTTCTGACTCACATACAGTAGATCACTTTTTACTCTGTGTTACCATTTTGACTGGTCGTCATTGGCATGGGGTGGATATAGGGCATAGG
ATTACTTGTCTCAGAAGCTGTCATAGAATTTCTTGCTGCCAATTAAAAAACCTGTGTTCTTTACACACTACACGTATAAATATTGTAACT
GTTCATCTTTGTTGTTTTATCACTGTAAGCCTGTCAAATCATAGTATCCTAAGCATCTGTAAATGCTAATTTTGCATTTTTGGAAAAACC
CATTCCTTCCAAGCTAGTGTTTTTCATTGGCTCCAGGTCTAATTTTTCACTGTGGTCCCTGGCAGCCAGTCTTTTGAAGTTTAAAGATTA
CCTGTCTCTTGACTGCAGTACCTTTTCTTTAATTTTTACCAAAAATATCCAGAGGTTACTGGAGTTCTTATTCAATATAAGGAAAGTTTG
CTGCACTTTATTACCAAGCCTCTGGGATTTTACCAGTCAAACATATTTGTGCATTACATTTCATTTCTTGTGAGCTAGCTGGCTGTCCAT
ATTGAATGTTGACCCATTTGAGTACGCTAAAAGGCTTACAGTATCAGACACGATCATGGTTTTAGATCCCATAATAAAAATGAATGTTTT
TCTTATAAAAAATTATACAAATGCTGAAGTGAGATTCTACTATTGTTCATTGCTTCCTTTTCTTTTTCCTTTTGCGATTTTCACTGATTA
ATAGCACATTTCTTCACAAAATTAGATAAAGTTGGTCAAAGACCAGATATTCTGGAATGGAAATTGTAAAGCTTAATCAAAAAGAATAGC
CAGTACAGCATACAATCTCAGAAACTTAGAAGCAAGTAGAAAATAATTGGTTGATGTAAACGAAAGTGCCATTTTAGTAAAGGCAGGAAA
AAAATAGCAATATTTGAGTTATGTAAGGATAAAAAATCCACTGACTTGTATTTTTGCACAAGAGGCTGGTCTGAATATGATTGTTCACAT
TAAGAGTGTTTATTCGTCGGTTCATTTTGGGGATTTTCCCCCTTGATGTTTTGACAGATTGAAGTGAGCTTTAGTGAGCAAAAGGATCAG
AATGCAGGGAACACTAAGCTGTGATGAAGAAAGTGTGGTAAAAAGCCAGAGTAGTTTTATACAGACAAAACCAGTGTCAGGCCTTTGCAG
TAGGCTTGAGTGAACTTCTGATCTAGATTTGAAAGTAAATTTTATGAAGACATTGCCCATTTTTACTTCCTCATTCATTATTGTACCAGC
ATCATAGCTTTATTACTCTAATCCCAGGTAAGTCAAGCCTACAATGCCCTAGAGGAAGAGTAAAACCAGAAATTCATGCTGGCTTAAATA

>In-frame_ENST00000267229_ENST00000369070_TCGA-59-2354_RBM26_chr13_79979838_-_ATG5_chr6_106649964_length(amino acids)=97AA_start in transcript=945_stop in transcript=1238
MFCHLITYSFVTFQVLSDSHTVDHFLLCVTILTGRHWHGVDIGHRITCLRSCHRISCCQLKNLCSLHTTRINIVTVHLCCFITVSLSNHS

--------------------------------------------------------------
>In-frame_ENST00000267229_ENST00000369076_TCGA-59-2354_RBM26_chr13_79979838_-_ATG5_chr6_106649964_length(transcript)=2404nt_BP=85nt
TAGGGCCGCTGTGGATGGTTTCTAAAATGATCATTGAAAACTTCGAGGCACTCAAGTCCTGGCTCAGCAAGACTCTCGAGCCCATACAAC
GACTGAAAGACCTTTCATTCAGAAGCTGTTTCGTCCTGTGGCTGCAGATGGACAGTTGCACACACTAGGAGATCTCCTCAAAGAAGTTTG
TCCTTCTGCTATTGATCCTGAAGATGGGGAAAAAAAGAATCAAGTGATGATTCATGGAATTGAGCCAATGTTGGAAACACCTCTGCAGTG
GCTGAGTGAACATCTGAGCTACCCGGATAATTTTCTTCATATTAGTATCATCCCACAGCCAACAGATTGAAGGATCAACTATTTGCCTGA
ACAGAATCATCCTTAAATGGGATTTATCAGAGCATGTCACCCTTTTGCTTCAATCAGGTTTGGTGGAGGCAACCTGACCAGAAACACTTC
GCTGCTGCAAGCCAGACAGGAAAAAGATTCCATGTCAGATAAGGCAACTGGGCTGGTCTTACTTTGCATCACCTCTGCTTTCCTCCACTG
CCATCATTAAACCTCAGCTGTGACATGAAAGACTTACCGGACCACTGAAGGTCTTCTGTAAAATATAATGAAGCTGAAACCTTTGGCCTA
AGAAGAAAATGGAAGTATGTGCCACTCGATTTGTATTTCTGATTAACAAATAAACAGGGGTATTTCCTAAGGTGACCATGGTTGAACTTT
AGCTCATGAAAGTGGAAACATTGGTTTAATTTTCAAGAGAATTAAGAAAGTAAAAGAGAAATTCTGTTATCAATAACTTGCAAGTAATTT
TTTGTAAAAGATTGAATTACAGTAAACCCATCTTTCCTTAACGAAAATTTCCTATGTTTACAGTCTGTCTATTGGTATGCAATCTTGTAA
CTTTGATAATGAACAGTGAGAGATTTTTAAATAAAGCCTCTAAATATGTTTTGTCATTTAATAACATACAGTTTTGTCACTTTTCAAGTA
CTTTCTGACTCACATACAGTAGATCACTTTTTACTCTGTGTTACCATTTTGACTGGTCGTCATTGGCATGGGGTGGATATAGGGCATAGG
ATTACTTGTCTCAGAAGCTGTCATAGAATTTCTTGCTGCCAATTAAAAAACCTGTGTTCTTTACACACTACACGTATAAATATTGTAACT
GTTCATCTTTGTTGTTTTATCACTGTAAGCCTGTCAAATCATAGTATCCTAAGCATCTGTAAATGCTAATTTTGCATTTTTGGAAAAACC
CATTCCTTCCAAGCTAGTGTTTTTCATTGGCTCCAGGTCTAATTTTTCACTGTGGTCCCTGGCAGCCAGTCTTTTGAAGTTTAAAGATTA
CCTGTCTCTTGACTGCAGTACCTTTTCTTTAATTTTTACCAAAAATATCCAGAGGTTACTGGAGTTCTTATTCAATATAAGGAAAGTTTG
CTGCACTTTATTACCAAGCCTCTGGGATTTTACCAGTCAAACATATTTGTGCATTACATTTCATTTCTTGTGAGCTAGCTGGCTGTCCAT
ATTGAATGTTGACCCATTTGAGTACGCTAAAAGGCTTACAGTATCAGACACGATCATGGTTTTAGATCCCATAATAAAAATGAATGTTTT
TCTTATAAAAAATTATACAAATGCTGAAGTGAGATTCTACTATTGTTCATTGCTTCCTTTTCTTTTTCCTTTTGCGATTTTCACTGATTA
ATAGCACATTTCTTCACAAAATTAGATAAAGTTGGTCAAAGACCAGATATTCTGGAATGGAAATTGTAAAGCTTAATCAAAAAGAATAGC
CAGTACAGCATACAATCTCAGAAACTTAGAAGCAAGTAGAAAATAATTGGTTGATGTAAACGAAAGTGCCATTTTAGTAAAGGCAGGAAA
AAAATAGCAATATTTGAGTTATGTAAGGATAAAAAATCCACTGACTTGTATTTTTGCACAAGAGGCTGGTCTGAATATGATTGTTCACAT
TAAGAGTGTTTATTCGTCGGTTCATTTTGGGGATTTTCCCCCTTGATGTTTTGACAGATTGAAGTGAGCTTTAGTGAGCAAAAGGATCAG
AATGCAGGGAACACTAAGCTGTGATGAAGAAAGTGTGGTAAAAAGCCAGAGTAGTTTTATACAGACAAAACCAGTGTCAGGCCTTTGCAG
TAGGCTTGAGTGAACTTCTGATCTAGATTTGAAAGTAAATTTTATGAAGACATTGCCCATTTTTACTTCCTCATTCATTATTGTACCAGC
ATCATAGCTTTATTACTCTAATCCCAGGTAAGTCAAGCCTACAATGCCCTAGAGGAAGAGTAAAACCAGAAATTCATGCTGGCTTAAATA

>In-frame_ENST00000267229_ENST00000369076_TCGA-59-2354_RBM26_chr13_79979838_-_ATG5_chr6_106649964_length(amino acids)=97AA_start in transcript=945_stop in transcript=1238
MFCHLITYSFVTFQVLSDSHTVDHFLLCVTILTGRHWHGVDIGHRITCLRSCHRISCCQLKNLCSLHTTRINIVTVHLCCFITVSLSNHS

--------------------------------------------------------------
>In-frame_ENST00000438737_ENST00000343245_TCGA-59-2354_RBM26_chr13_79979838_-_ATG5_chr6_106649964_length(transcript)=2831nt_BP=512nt
GCTGGGAGCCGGGAAGACCCCCTGAATCGTTCCCATTGAGCTGCCCTTCGCCTTCGCTTTCTTTACTTTTGCCTTTTCGACGTAGCCAAC
AAGCACCTGGTCCCGAGGCTGAGAGAAGGCTCGGGTCTAAGCGCGTGTCGCGCTTCCGGTCTGGGTAGATTTGCTGGGGAAGAGGGAAGG
GGGAGGGCCCGGGCAAACCGTTGCTGTTTCAGCCCGGGCTGGGGGCCGGGGACGGGGAGCTCCTGGCACCCCGTGCACTTGTGGCCTGCG
GCGGTCCTTGCAGAGCTGTTCGCCGACCGGGGCCCGCGGGAACCTGCCACCGGCGCCTCCCACCGCGGCCCACGCGGGCGGCGCGCGGAG
GAGGGGGCGGGGGCAGCGGCGGCTGTAGCGGCCGCGACCTGGGCGGGCGGAGGAGTGTGACGGGCCTTAGGGCCGCTGTGGATGGTTTCT
AAAATGATCATTGAAAACTTCGAGGCACTCAAGTCCTGGCTCAGCAAGACTCTCGAGCCCATACAACGACTGAAAGACCTTTCATTCAGA
AGCTGTTTCGTCCTGTGGCTGCAGATGGACAGTTGCACACACTAGGAGATCTCCTCAAAGAAGTTTGTCCTTCTGCTATTGATCCTGAAG
ATGGGGAAAAAAAGAATCAAGTGATGATTCATGGAATTGAGCCAATGTTGGAAACACCTCTGCAGTGGCTGAGTGAACATCTGAGCTACC
CGGATAATTTTCTTCATATTAGTATCATCCCACAGCCAACAGATTGAAGGATCAACTATTTGCCTGAACAGAATCATCCTTAAATGGGAT
TTATCAGAGCATGTCACCCTTTTGCTTCAATCAGGTTTGGTGGAGGCAACCTGACCAGAAACACTTCGCTGCTGCAAGCCAGACAGGAAA
AAGATTCCATGTCAGATAAGGCAACTGGGCTGGTCTTACTTTGCATCACCTCTGCTTTCCTCCACTGCCATCATTAAACCTCAGCTGTGA
CATGAAAGACTTACCGGACCACTGAAGGTCTTCTGTAAAATATAATGAAGCTGAAACCTTTGGCCTAAGAAGAAAATGGAAGTATGTGCC
ACTCGATTTGTATTTCTGATTAACAAATAAACAGGGGTATTTCCTAAGGTGACCATGGTTGAACTTTAGCTCATGAAAGTGGAAACATTG
GTTTAATTTTCAAGAGAATTAAGAAAGTAAAAGAGAAATTCTGTTATCAATAACTTGCAAGTAATTTTTTGTAAAAGATTGAATTACAGT
AAACCCATCTTTCCTTAACGAAAATTTCCTATGTTTACAGTCTGTCTATTGGTATGCAATCTTGTAACTTTGATAATGAACAGTGAGAGA
TTTTTAAATAAAGCCTCTAAATATGTTTTGTCATTTAATAACATACAGTTTTGTCACTTTTCAAGTACTTTCTGACTCACATACAGTAGA
TCACTTTTTACTCTGTGTTACCATTTTGACTGGTCGTCATTGGCATGGGGTGGATATAGGGCATAGGATTACTTGTCTCAGAAGCTGTCA
TAGAATTTCTTGCTGCCAATTAAAAAACCTGTGTTCTTTACACACTACACGTATAAATATTGTAACTGTTCATCTTTGTTGTTTTATCAC
TGTAAGCCTGTCAAATCATAGTATCCTAAGCATCTGTAAATGCTAATTTTGCATTTTTGGAAAAACCCATTCCTTCCAAGCTAGTGTTTT
TCATTGGCTCCAGGTCTAATTTTTCACTGTGGTCCCTGGCAGCCAGTCTTTTGAAGTTTAAAGATTACCTGTCTCTTGACTGCAGTACCT
TTTCTTTAATTTTTACCAAAAATATCCAGAGGTTACTGGAGTTCTTATTCAATATAAGGAAAGTTTGCTGCACTTTATTACCAAGCCTCT
GGGATTTTACCAGTCAAACATATTTGTGCATTACATTTCATTTCTTGTGAGCTAGCTGGCTGTCCATATTGAATGTTGACCCATTTGAGT
ACGCTAAAAGGCTTACAGTATCAGACACGATCATGGTTTTAGATCCCATAATAAAAATGAATGTTTTTCTTATAAAAAATTATACAAATG
CTGAAGTGAGATTCTACTATTGTTCATTGCTTCCTTTTCTTTTTCCTTTTGCGATTTTCACTGATTAATAGCACATTTCTTCACAAAATT
AGATAAAGTTGGTCAAAGACCAGATATTCTGGAATGGAAATTGTAAAGCTTAATCAAAAAGAATAGCCAGTACAGCATACAATCTCAGAA
ACTTAGAAGCAAGTAGAAAATAATTGGTTGATGTAAACGAAAGTGCCATTTTAGTAAAGGCAGGAAAAAAATAGCAATATTTGAGTTATG
TAAGGATAAAAAATCCACTGACTTGTATTTTTGCACAAGAGGCTGGTCTGAATATGATTGTTCACATTAAGAGTGTTTATTCGTCGGTTC
ATTTTGGGGATTTTCCCCCTTGATGTTTTGACAGATTGAAGTGAGCTTTAGTGAGCAAAAGGATCAGAATGCAGGGAACACTAAGCTGTG
ATGAAGAAAGTGTGGTAAAAAGCCAGAGTAGTTTTATACAGACAAAACCAGTGTCAGGCCTTTGCAGTAGGCTTGAGTGAACTTCTGATC
TAGATTTGAAAGTAAATTTTATGAAGACATTGCCCATTTTTACTTCCTCATTCATTATTGTACCAGCATCATAGCTTTATTACTCTAATC
CCAGGTAAGTCAAGCCTACAATGCCCTAGAGGAAGAGTAAAACCAGAAATTCATGCTGGCTTAAATAATCTATTTTTGTTTCTTTTCATT

>In-frame_ENST00000438737_ENST00000343245_TCGA-59-2354_RBM26_chr13_79979838_-_ATG5_chr6_106649964_length(amino acids)=169AA_start in transcript=571_stop in transcript=62
MSICSHRTKQLLNERSFSRCMGSRVLLSQDLSASKFSMIILETIHSGPKARHTPPPAQVAAATAAAAPAPSSARRPRGPRWEAPVAGSRG

--------------------------------------------------------------
>In-frame_ENST00000438737_ENST00000369070_TCGA-59-2354_RBM26_chr13_79979838_-_ATG5_chr6_106649964_length(transcript)=2831nt_BP=512nt
GCTGGGAGCCGGGAAGACCCCCTGAATCGTTCCCATTGAGCTGCCCTTCGCCTTCGCTTTCTTTACTTTTGCCTTTTCGACGTAGCCAAC
AAGCACCTGGTCCCGAGGCTGAGAGAAGGCTCGGGTCTAAGCGCGTGTCGCGCTTCCGGTCTGGGTAGATTTGCTGGGGAAGAGGGAAGG
GGGAGGGCCCGGGCAAACCGTTGCTGTTTCAGCCCGGGCTGGGGGCCGGGGACGGGGAGCTCCTGGCACCCCGTGCACTTGTGGCCTGCG
GCGGTCCTTGCAGAGCTGTTCGCCGACCGGGGCCCGCGGGAACCTGCCACCGGCGCCTCCCACCGCGGCCCACGCGGGCGGCGCGCGGAG
GAGGGGGCGGGGGCAGCGGCGGCTGTAGCGGCCGCGACCTGGGCGGGCGGAGGAGTGTGACGGGCCTTAGGGCCGCTGTGGATGGTTTCT
AAAATGATCATTGAAAACTTCGAGGCACTCAAGTCCTGGCTCAGCAAGACTCTCGAGCCCATACAACGACTGAAAGACCTTTCATTCAGA
AGCTGTTTCGTCCTGTGGCTGCAGATGGACAGTTGCACACACTAGGAGATCTCCTCAAAGAAGTTTGTCCTTCTGCTATTGATCCTGAAG
ATGGGGAAAAAAAGAATCAAGTGATGATTCATGGAATTGAGCCAATGTTGGAAACACCTCTGCAGTGGCTGAGTGAACATCTGAGCTACC
CGGATAATTTTCTTCATATTAGTATCATCCCACAGCCAACAGATTGAAGGATCAACTATTTGCCTGAACAGAATCATCCTTAAATGGGAT
TTATCAGAGCATGTCACCCTTTTGCTTCAATCAGGTTTGGTGGAGGCAACCTGACCAGAAACACTTCGCTGCTGCAAGCCAGACAGGAAA
AAGATTCCATGTCAGATAAGGCAACTGGGCTGGTCTTACTTTGCATCACCTCTGCTTTCCTCCACTGCCATCATTAAACCTCAGCTGTGA
CATGAAAGACTTACCGGACCACTGAAGGTCTTCTGTAAAATATAATGAAGCTGAAACCTTTGGCCTAAGAAGAAAATGGAAGTATGTGCC
ACTCGATTTGTATTTCTGATTAACAAATAAACAGGGGTATTTCCTAAGGTGACCATGGTTGAACTTTAGCTCATGAAAGTGGAAACATTG
GTTTAATTTTCAAGAGAATTAAGAAAGTAAAAGAGAAATTCTGTTATCAATAACTTGCAAGTAATTTTTTGTAAAAGATTGAATTACAGT
AAACCCATCTTTCCTTAACGAAAATTTCCTATGTTTACAGTCTGTCTATTGGTATGCAATCTTGTAACTTTGATAATGAACAGTGAGAGA
TTTTTAAATAAAGCCTCTAAATATGTTTTGTCATTTAATAACATACAGTTTTGTCACTTTTCAAGTACTTTCTGACTCACATACAGTAGA
TCACTTTTTACTCTGTGTTACCATTTTGACTGGTCGTCATTGGCATGGGGTGGATATAGGGCATAGGATTACTTGTCTCAGAAGCTGTCA
TAGAATTTCTTGCTGCCAATTAAAAAACCTGTGTTCTTTACACACTACACGTATAAATATTGTAACTGTTCATCTTTGTTGTTTTATCAC
TGTAAGCCTGTCAAATCATAGTATCCTAAGCATCTGTAAATGCTAATTTTGCATTTTTGGAAAAACCCATTCCTTCCAAGCTAGTGTTTT
TCATTGGCTCCAGGTCTAATTTTTCACTGTGGTCCCTGGCAGCCAGTCTTTTGAAGTTTAAAGATTACCTGTCTCTTGACTGCAGTACCT
TTTCTTTAATTTTTACCAAAAATATCCAGAGGTTACTGGAGTTCTTATTCAATATAAGGAAAGTTTGCTGCACTTTATTACCAAGCCTCT
GGGATTTTACCAGTCAAACATATTTGTGCATTACATTTCATTTCTTGTGAGCTAGCTGGCTGTCCATATTGAATGTTGACCCATTTGAGT
ACGCTAAAAGGCTTACAGTATCAGACACGATCATGGTTTTAGATCCCATAATAAAAATGAATGTTTTTCTTATAAAAAATTATACAAATG
CTGAAGTGAGATTCTACTATTGTTCATTGCTTCCTTTTCTTTTTCCTTTTGCGATTTTCACTGATTAATAGCACATTTCTTCACAAAATT
AGATAAAGTTGGTCAAAGACCAGATATTCTGGAATGGAAATTGTAAAGCTTAATCAAAAAGAATAGCCAGTACAGCATACAATCTCAGAA
ACTTAGAAGCAAGTAGAAAATAATTGGTTGATGTAAACGAAAGTGCCATTTTAGTAAAGGCAGGAAAAAAATAGCAATATTTGAGTTATG
TAAGGATAAAAAATCCACTGACTTGTATTTTTGCACAAGAGGCTGGTCTGAATATGATTGTTCACATTAAGAGTGTTTATTCGTCGGTTC
ATTTTGGGGATTTTCCCCCTTGATGTTTTGACAGATTGAAGTGAGCTTTAGTGAGCAAAAGGATCAGAATGCAGGGAACACTAAGCTGTG
ATGAAGAAAGTGTGGTAAAAAGCCAGAGTAGTTTTATACAGACAAAACCAGTGTCAGGCCTTTGCAGTAGGCTTGAGTGAACTTCTGATC
TAGATTTGAAAGTAAATTTTATGAAGACATTGCCCATTTTTACTTCCTCATTCATTATTGTACCAGCATCATAGCTTTATTACTCTAATC
CCAGGTAAGTCAAGCCTACAATGCCCTAGAGGAAGAGTAAAACCAGAAATTCATGCTGGCTTAAATAATCTATTTTTGTTTCTTTTCATT

>In-frame_ENST00000438737_ENST00000369070_TCGA-59-2354_RBM26_chr13_79979838_-_ATG5_chr6_106649964_length(amino acids)=169AA_start in transcript=571_stop in transcript=62
MSICSHRTKQLLNERSFSRCMGSRVLLSQDLSASKFSMIILETIHSGPKARHTPPPAQVAAATAAAAPAPSSARRPRGPRWEAPVAGSRG

--------------------------------------------------------------
>In-frame_ENST00000438737_ENST00000369076_TCGA-59-2354_RBM26_chr13_79979838_-_ATG5_chr6_106649964_length(transcript)=2831nt_BP=512nt
GCTGGGAGCCGGGAAGACCCCCTGAATCGTTCCCATTGAGCTGCCCTTCGCCTTCGCTTTCTTTACTTTTGCCTTTTCGACGTAGCCAAC
AAGCACCTGGTCCCGAGGCTGAGAGAAGGCTCGGGTCTAAGCGCGTGTCGCGCTTCCGGTCTGGGTAGATTTGCTGGGGAAGAGGGAAGG
GGGAGGGCCCGGGCAAACCGTTGCTGTTTCAGCCCGGGCTGGGGGCCGGGGACGGGGAGCTCCTGGCACCCCGTGCACTTGTGGCCTGCG
GCGGTCCTTGCAGAGCTGTTCGCCGACCGGGGCCCGCGGGAACCTGCCACCGGCGCCTCCCACCGCGGCCCACGCGGGCGGCGCGCGGAG
GAGGGGGCGGGGGCAGCGGCGGCTGTAGCGGCCGCGACCTGGGCGGGCGGAGGAGTGTGACGGGCCTTAGGGCCGCTGTGGATGGTTTCT
AAAATGATCATTGAAAACTTCGAGGCACTCAAGTCCTGGCTCAGCAAGACTCTCGAGCCCATACAACGACTGAAAGACCTTTCATTCAGA
AGCTGTTTCGTCCTGTGGCTGCAGATGGACAGTTGCACACACTAGGAGATCTCCTCAAAGAAGTTTGTCCTTCTGCTATTGATCCTGAAG
ATGGGGAAAAAAAGAATCAAGTGATGATTCATGGAATTGAGCCAATGTTGGAAACACCTCTGCAGTGGCTGAGTGAACATCTGAGCTACC
CGGATAATTTTCTTCATATTAGTATCATCCCACAGCCAACAGATTGAAGGATCAACTATTTGCCTGAACAGAATCATCCTTAAATGGGAT
TTATCAGAGCATGTCACCCTTTTGCTTCAATCAGGTTTGGTGGAGGCAACCTGACCAGAAACACTTCGCTGCTGCAAGCCAGACAGGAAA
AAGATTCCATGTCAGATAAGGCAACTGGGCTGGTCTTACTTTGCATCACCTCTGCTTTCCTCCACTGCCATCATTAAACCTCAGCTGTGA
CATGAAAGACTTACCGGACCACTGAAGGTCTTCTGTAAAATATAATGAAGCTGAAACCTTTGGCCTAAGAAGAAAATGGAAGTATGTGCC
ACTCGATTTGTATTTCTGATTAACAAATAAACAGGGGTATTTCCTAAGGTGACCATGGTTGAACTTTAGCTCATGAAAGTGGAAACATTG
GTTTAATTTTCAAGAGAATTAAGAAAGTAAAAGAGAAATTCTGTTATCAATAACTTGCAAGTAATTTTTTGTAAAAGATTGAATTACAGT
AAACCCATCTTTCCTTAACGAAAATTTCCTATGTTTACAGTCTGTCTATTGGTATGCAATCTTGTAACTTTGATAATGAACAGTGAGAGA
TTTTTAAATAAAGCCTCTAAATATGTTTTGTCATTTAATAACATACAGTTTTGTCACTTTTCAAGTACTTTCTGACTCACATACAGTAGA
TCACTTTTTACTCTGTGTTACCATTTTGACTGGTCGTCATTGGCATGGGGTGGATATAGGGCATAGGATTACTTGTCTCAGAAGCTGTCA
TAGAATTTCTTGCTGCCAATTAAAAAACCTGTGTTCTTTACACACTACACGTATAAATATTGTAACTGTTCATCTTTGTTGTTTTATCAC
TGTAAGCCTGTCAAATCATAGTATCCTAAGCATCTGTAAATGCTAATTTTGCATTTTTGGAAAAACCCATTCCTTCCAAGCTAGTGTTTT
TCATTGGCTCCAGGTCTAATTTTTCACTGTGGTCCCTGGCAGCCAGTCTTTTGAAGTTTAAAGATTACCTGTCTCTTGACTGCAGTACCT
TTTCTTTAATTTTTACCAAAAATATCCAGAGGTTACTGGAGTTCTTATTCAATATAAGGAAAGTTTGCTGCACTTTATTACCAAGCCTCT
GGGATTTTACCAGTCAAACATATTTGTGCATTACATTTCATTTCTTGTGAGCTAGCTGGCTGTCCATATTGAATGTTGACCCATTTGAGT
ACGCTAAAAGGCTTACAGTATCAGACACGATCATGGTTTTAGATCCCATAATAAAAATGAATGTTTTTCTTATAAAAAATTATACAAATG
CTGAAGTGAGATTCTACTATTGTTCATTGCTTCCTTTTCTTTTTCCTTTTGCGATTTTCACTGATTAATAGCACATTTCTTCACAAAATT
AGATAAAGTTGGTCAAAGACCAGATATTCTGGAATGGAAATTGTAAAGCTTAATCAAAAAGAATAGCCAGTACAGCATACAATCTCAGAA
ACTTAGAAGCAAGTAGAAAATAATTGGTTGATGTAAACGAAAGTGCCATTTTAGTAAAGGCAGGAAAAAAATAGCAATATTTGAGTTATG
TAAGGATAAAAAATCCACTGACTTGTATTTTTGCACAAGAGGCTGGTCTGAATATGATTGTTCACATTAAGAGTGTTTATTCGTCGGTTC
ATTTTGGGGATTTTCCCCCTTGATGTTTTGACAGATTGAAGTGAGCTTTAGTGAGCAAAAGGATCAGAATGCAGGGAACACTAAGCTGTG
ATGAAGAAAGTGTGGTAAAAAGCCAGAGTAGTTTTATACAGACAAAACCAGTGTCAGGCCTTTGCAGTAGGCTTGAGTGAACTTCTGATC
TAGATTTGAAAGTAAATTTTATGAAGACATTGCCCATTTTTACTTCCTCATTCATTATTGTACCAGCATCATAGCTTTATTACTCTAATC
CCAGGTAAGTCAAGCCTACAATGCCCTAGAGGAAGAGTAAAACCAGAAATTCATGCTGGCTTAAATAATCTATTTTTGTTTCTTTTCATT

>In-frame_ENST00000438737_ENST00000369076_TCGA-59-2354_RBM26_chr13_79979838_-_ATG5_chr6_106649964_length(amino acids)=169AA_start in transcript=571_stop in transcript=62
MSICSHRTKQLLNERSFSRCMGSRVLLSQDLSASKFSMIILETIHSGPKARHTPPPAQVAAATAAAAPAPSSARRPRGPRWEAPVAGSRG

--------------------------------------------------------------
>In-frame_ENST00000438724_ENST00000343245_TCGA-59-2354_RBM26_chr13_79979838_-_ATG5_chr6_106649964_length(transcript)=2446nt_BP=127nt
TAGCGGCCGCGACCTGGGCGGGCGGAGGAGTGTGACGGGCCTTAGGGCCGCTGTGGATGGTTTCTAAAATGATCATTGAAAACTTCGAGG
CACTCAAGTCCTGGCTCAGCAAGACTCTCGAGCCCATACAACGACTGAAAGACCTTTCATTCAGAAGCTGTTTCGTCCTGTGGCTGCAGA
TGGACAGTTGCACACACTAGGAGATCTCCTCAAAGAAGTTTGTCCTTCTGCTATTGATCCTGAAGATGGGGAAAAAAAGAATCAAGTGAT
GATTCATGGAATTGAGCCAATGTTGGAAACACCTCTGCAGTGGCTGAGTGAACATCTGAGCTACCCGGATAATTTTCTTCATATTAGTAT
CATCCCACAGCCAACAGATTGAAGGATCAACTATTTGCCTGAACAGAATCATCCTTAAATGGGATTTATCAGAGCATGTCACCCTTTTGC
TTCAATCAGGTTTGGTGGAGGCAACCTGACCAGAAACACTTCGCTGCTGCAAGCCAGACAGGAAAAAGATTCCATGTCAGATAAGGCAAC
TGGGCTGGTCTTACTTTGCATCACCTCTGCTTTCCTCCACTGCCATCATTAAACCTCAGCTGTGACATGAAAGACTTACCGGACCACTGA
AGGTCTTCTGTAAAATATAATGAAGCTGAAACCTTTGGCCTAAGAAGAAAATGGAAGTATGTGCCACTCGATTTGTATTTCTGATTAACA
AATAAACAGGGGTATTTCCTAAGGTGACCATGGTTGAACTTTAGCTCATGAAAGTGGAAACATTGGTTTAATTTTCAAGAGAATTAAGAA
AGTAAAAGAGAAATTCTGTTATCAATAACTTGCAAGTAATTTTTTGTAAAAGATTGAATTACAGTAAACCCATCTTTCCTTAACGAAAAT
TTCCTATGTTTACAGTCTGTCTATTGGTATGCAATCTTGTAACTTTGATAATGAACAGTGAGAGATTTTTAAATAAAGCCTCTAAATATG
TTTTGTCATTTAATAACATACAGTTTTGTCACTTTTCAAGTACTTTCTGACTCACATACAGTAGATCACTTTTTACTCTGTGTTACCATT
TTGACTGGTCGTCATTGGCATGGGGTGGATATAGGGCATAGGATTACTTGTCTCAGAAGCTGTCATAGAATTTCTTGCTGCCAATTAAAA
AACCTGTGTTCTTTACACACTACACGTATAAATATTGTAACTGTTCATCTTTGTTGTTTTATCACTGTAAGCCTGTCAAATCATAGTATC
CTAAGCATCTGTAAATGCTAATTTTGCATTTTTGGAAAAACCCATTCCTTCCAAGCTAGTGTTTTTCATTGGCTCCAGGTCTAATTTTTC
ACTGTGGTCCCTGGCAGCCAGTCTTTTGAAGTTTAAAGATTACCTGTCTCTTGACTGCAGTACCTTTTCTTTAATTTTTACCAAAAATAT
CCAGAGGTTACTGGAGTTCTTATTCAATATAAGGAAAGTTTGCTGCACTTTATTACCAAGCCTCTGGGATTTTACCAGTCAAACATATTT
GTGCATTACATTTCATTTCTTGTGAGCTAGCTGGCTGTCCATATTGAATGTTGACCCATTTGAGTACGCTAAAAGGCTTACAGTATCAGA
CACGATCATGGTTTTAGATCCCATAATAAAAATGAATGTTTTTCTTATAAAAAATTATACAAATGCTGAAGTGAGATTCTACTATTGTTC
ATTGCTTCCTTTTCTTTTTCCTTTTGCGATTTTCACTGATTAATAGCACATTTCTTCACAAAATTAGATAAAGTTGGTCAAAGACCAGAT
ATTCTGGAATGGAAATTGTAAAGCTTAATCAAAAAGAATAGCCAGTACAGCATACAATCTCAGAAACTTAGAAGCAAGTAGAAAATAATT
GGTTGATGTAAACGAAAGTGCCATTTTAGTAAAGGCAGGAAAAAAATAGCAATATTTGAGTTATGTAAGGATAAAAAATCCACTGACTTG
TATTTTTGCACAAGAGGCTGGTCTGAATATGATTGTTCACATTAAGAGTGTTTATTCGTCGGTTCATTTTGGGGATTTTCCCCCTTGATG
TTTTGACAGATTGAAGTGAGCTTTAGTGAGCAAAAGGATCAGAATGCAGGGAACACTAAGCTGTGATGAAGAAAGTGTGGTAAAAAGCCA
GAGTAGTTTTATACAGACAAAACCAGTGTCAGGCCTTTGCAGTAGGCTTGAGTGAACTTCTGATCTAGATTTGAAAGTAAATTTTATGAA
GACATTGCCCATTTTTACTTCCTCATTCATTATTGTACCAGCATCATAGCTTTATTACTCTAATCCCAGGTAAGTCAAGCCTACAATGCC
CTAGAGGAAGAGTAAAACCAGAAATTCATGCTGGCTTAAATAATCTATTTTTGTTTCTTTTCATTTGAATATTTAAATTTTATGGTTTAT

>In-frame_ENST00000438724_ENST00000343245_TCGA-59-2354_RBM26_chr13_79979838_-_ATG5_chr6_106649964_length(amino acids)=97AA_start in transcript=987_stop in transcript=1280
MFCHLITYSFVTFQVLSDSHTVDHFLLCVTILTGRHWHGVDIGHRITCLRSCHRISCCQLKNLCSLHTTRINIVTVHLCCFITVSLSNHS

--------------------------------------------------------------
>In-frame_ENST00000438724_ENST00000369070_TCGA-59-2354_RBM26_chr13_79979838_-_ATG5_chr6_106649964_length(transcript)=2446nt_BP=127nt
TAGCGGCCGCGACCTGGGCGGGCGGAGGAGTGTGACGGGCCTTAGGGCCGCTGTGGATGGTTTCTAAAATGATCATTGAAAACTTCGAGG
CACTCAAGTCCTGGCTCAGCAAGACTCTCGAGCCCATACAACGACTGAAAGACCTTTCATTCAGAAGCTGTTTCGTCCTGTGGCTGCAGA
TGGACAGTTGCACACACTAGGAGATCTCCTCAAAGAAGTTTGTCCTTCTGCTATTGATCCTGAAGATGGGGAAAAAAAGAATCAAGTGAT
GATTCATGGAATTGAGCCAATGTTGGAAACACCTCTGCAGTGGCTGAGTGAACATCTGAGCTACCCGGATAATTTTCTTCATATTAGTAT
CATCCCACAGCCAACAGATTGAAGGATCAACTATTTGCCTGAACAGAATCATCCTTAAATGGGATTTATCAGAGCATGTCACCCTTTTGC
TTCAATCAGGTTTGGTGGAGGCAACCTGACCAGAAACACTTCGCTGCTGCAAGCCAGACAGGAAAAAGATTCCATGTCAGATAAGGCAAC
TGGGCTGGTCTTACTTTGCATCACCTCTGCTTTCCTCCACTGCCATCATTAAACCTCAGCTGTGACATGAAAGACTTACCGGACCACTGA
AGGTCTTCTGTAAAATATAATGAAGCTGAAACCTTTGGCCTAAGAAGAAAATGGAAGTATGTGCCACTCGATTTGTATTTCTGATTAACA
AATAAACAGGGGTATTTCCTAAGGTGACCATGGTTGAACTTTAGCTCATGAAAGTGGAAACATTGGTTTAATTTTCAAGAGAATTAAGAA
AGTAAAAGAGAAATTCTGTTATCAATAACTTGCAAGTAATTTTTTGTAAAAGATTGAATTACAGTAAACCCATCTTTCCTTAACGAAAAT
TTCCTATGTTTACAGTCTGTCTATTGGTATGCAATCTTGTAACTTTGATAATGAACAGTGAGAGATTTTTAAATAAAGCCTCTAAATATG
TTTTGTCATTTAATAACATACAGTTTTGTCACTTTTCAAGTACTTTCTGACTCACATACAGTAGATCACTTTTTACTCTGTGTTACCATT
TTGACTGGTCGTCATTGGCATGGGGTGGATATAGGGCATAGGATTACTTGTCTCAGAAGCTGTCATAGAATTTCTTGCTGCCAATTAAAA
AACCTGTGTTCTTTACACACTACACGTATAAATATTGTAACTGTTCATCTTTGTTGTTTTATCACTGTAAGCCTGTCAAATCATAGTATC
CTAAGCATCTGTAAATGCTAATTTTGCATTTTTGGAAAAACCCATTCCTTCCAAGCTAGTGTTTTTCATTGGCTCCAGGTCTAATTTTTC
ACTGTGGTCCCTGGCAGCCAGTCTTTTGAAGTTTAAAGATTACCTGTCTCTTGACTGCAGTACCTTTTCTTTAATTTTTACCAAAAATAT
CCAGAGGTTACTGGAGTTCTTATTCAATATAAGGAAAGTTTGCTGCACTTTATTACCAAGCCTCTGGGATTTTACCAGTCAAACATATTT
GTGCATTACATTTCATTTCTTGTGAGCTAGCTGGCTGTCCATATTGAATGTTGACCCATTTGAGTACGCTAAAAGGCTTACAGTATCAGA
CACGATCATGGTTTTAGATCCCATAATAAAAATGAATGTTTTTCTTATAAAAAATTATACAAATGCTGAAGTGAGATTCTACTATTGTTC
ATTGCTTCCTTTTCTTTTTCCTTTTGCGATTTTCACTGATTAATAGCACATTTCTTCACAAAATTAGATAAAGTTGGTCAAAGACCAGAT
ATTCTGGAATGGAAATTGTAAAGCTTAATCAAAAAGAATAGCCAGTACAGCATACAATCTCAGAAACTTAGAAGCAAGTAGAAAATAATT
GGTTGATGTAAACGAAAGTGCCATTTTAGTAAAGGCAGGAAAAAAATAGCAATATTTGAGTTATGTAAGGATAAAAAATCCACTGACTTG
TATTTTTGCACAAGAGGCTGGTCTGAATATGATTGTTCACATTAAGAGTGTTTATTCGTCGGTTCATTTTGGGGATTTTCCCCCTTGATG
TTTTGACAGATTGAAGTGAGCTTTAGTGAGCAAAAGGATCAGAATGCAGGGAACACTAAGCTGTGATGAAGAAAGTGTGGTAAAAAGCCA
GAGTAGTTTTATACAGACAAAACCAGTGTCAGGCCTTTGCAGTAGGCTTGAGTGAACTTCTGATCTAGATTTGAAAGTAAATTTTATGAA
GACATTGCCCATTTTTACTTCCTCATTCATTATTGTACCAGCATCATAGCTTTATTACTCTAATCCCAGGTAAGTCAAGCCTACAATGCC
CTAGAGGAAGAGTAAAACCAGAAATTCATGCTGGCTTAAATAATCTATTTTTGTTTCTTTTCATTTGAATATTTAAATTTTATGGTTTAT

>In-frame_ENST00000438724_ENST00000369070_TCGA-59-2354_RBM26_chr13_79979838_-_ATG5_chr6_106649964_length(amino acids)=97AA_start in transcript=987_stop in transcript=1280
MFCHLITYSFVTFQVLSDSHTVDHFLLCVTILTGRHWHGVDIGHRITCLRSCHRISCCQLKNLCSLHTTRINIVTVHLCCFITVSLSNHS

--------------------------------------------------------------
>In-frame_ENST00000438724_ENST00000369076_TCGA-59-2354_RBM26_chr13_79979838_-_ATG5_chr6_106649964_length(transcript)=2446nt_BP=127nt
TAGCGGCCGCGACCTGGGCGGGCGGAGGAGTGTGACGGGCCTTAGGGCCGCTGTGGATGGTTTCTAAAATGATCATTGAAAACTTCGAGG
CACTCAAGTCCTGGCTCAGCAAGACTCTCGAGCCCATACAACGACTGAAAGACCTTTCATTCAGAAGCTGTTTCGTCCTGTGGCTGCAGA
TGGACAGTTGCACACACTAGGAGATCTCCTCAAAGAAGTTTGTCCTTCTGCTATTGATCCTGAAGATGGGGAAAAAAAGAATCAAGTGAT
GATTCATGGAATTGAGCCAATGTTGGAAACACCTCTGCAGTGGCTGAGTGAACATCTGAGCTACCCGGATAATTTTCTTCATATTAGTAT
CATCCCACAGCCAACAGATTGAAGGATCAACTATTTGCCTGAACAGAATCATCCTTAAATGGGATTTATCAGAGCATGTCACCCTTTTGC
TTCAATCAGGTTTGGTGGAGGCAACCTGACCAGAAACACTTCGCTGCTGCAAGCCAGACAGGAAAAAGATTCCATGTCAGATAAGGCAAC
TGGGCTGGTCTTACTTTGCATCACCTCTGCTTTCCTCCACTGCCATCATTAAACCTCAGCTGTGACATGAAAGACTTACCGGACCACTGA
AGGTCTTCTGTAAAATATAATGAAGCTGAAACCTTTGGCCTAAGAAGAAAATGGAAGTATGTGCCACTCGATTTGTATTTCTGATTAACA
AATAAACAGGGGTATTTCCTAAGGTGACCATGGTTGAACTTTAGCTCATGAAAGTGGAAACATTGGTTTAATTTTCAAGAGAATTAAGAA
AGTAAAAGAGAAATTCTGTTATCAATAACTTGCAAGTAATTTTTTGTAAAAGATTGAATTACAGTAAACCCATCTTTCCTTAACGAAAAT
TTCCTATGTTTACAGTCTGTCTATTGGTATGCAATCTTGTAACTTTGATAATGAACAGTGAGAGATTTTTAAATAAAGCCTCTAAATATG
TTTTGTCATTTAATAACATACAGTTTTGTCACTTTTCAAGTACTTTCTGACTCACATACAGTAGATCACTTTTTACTCTGTGTTACCATT
TTGACTGGTCGTCATTGGCATGGGGTGGATATAGGGCATAGGATTACTTGTCTCAGAAGCTGTCATAGAATTTCTTGCTGCCAATTAAAA
AACCTGTGTTCTTTACACACTACACGTATAAATATTGTAACTGTTCATCTTTGTTGTTTTATCACTGTAAGCCTGTCAAATCATAGTATC
CTAAGCATCTGTAAATGCTAATTTTGCATTTTTGGAAAAACCCATTCCTTCCAAGCTAGTGTTTTTCATTGGCTCCAGGTCTAATTTTTC
ACTGTGGTCCCTGGCAGCCAGTCTTTTGAAGTTTAAAGATTACCTGTCTCTTGACTGCAGTACCTTTTCTTTAATTTTTACCAAAAATAT
CCAGAGGTTACTGGAGTTCTTATTCAATATAAGGAAAGTTTGCTGCACTTTATTACCAAGCCTCTGGGATTTTACCAGTCAAACATATTT
GTGCATTACATTTCATTTCTTGTGAGCTAGCTGGCTGTCCATATTGAATGTTGACCCATTTGAGTACGCTAAAAGGCTTACAGTATCAGA
CACGATCATGGTTTTAGATCCCATAATAAAAATGAATGTTTTTCTTATAAAAAATTATACAAATGCTGAAGTGAGATTCTACTATTGTTC
ATTGCTTCCTTTTCTTTTTCCTTTTGCGATTTTCACTGATTAATAGCACATTTCTTCACAAAATTAGATAAAGTTGGTCAAAGACCAGAT
ATTCTGGAATGGAAATTGTAAAGCTTAATCAAAAAGAATAGCCAGTACAGCATACAATCTCAGAAACTTAGAAGCAAGTAGAAAATAATT
GGTTGATGTAAACGAAAGTGCCATTTTAGTAAAGGCAGGAAAAAAATAGCAATATTTGAGTTATGTAAGGATAAAAAATCCACTGACTTG
TATTTTTGCACAAGAGGCTGGTCTGAATATGATTGTTCACATTAAGAGTGTTTATTCGTCGGTTCATTTTGGGGATTTTCCCCCTTGATG
TTTTGACAGATTGAAGTGAGCTTTAGTGAGCAAAAGGATCAGAATGCAGGGAACACTAAGCTGTGATGAAGAAAGTGTGGTAAAAAGCCA
GAGTAGTTTTATACAGACAAAACCAGTGTCAGGCCTTTGCAGTAGGCTTGAGTGAACTTCTGATCTAGATTTGAAAGTAAATTTTATGAA
GACATTGCCCATTTTTACTTCCTCATTCATTATTGTACCAGCATCATAGCTTTATTACTCTAATCCCAGGTAAGTCAAGCCTACAATGCC
CTAGAGGAAGAGTAAAACCAGAAATTCATGCTGGCTTAAATAATCTATTTTTGTTTCTTTTCATTTGAATATTTAAATTTTATGGTTTAT

>In-frame_ENST00000438724_ENST00000369076_TCGA-59-2354_RBM26_chr13_79979838_-_ATG5_chr6_106649964_length(amino acids)=97AA_start in transcript=987_stop in transcript=1280
MFCHLITYSFVTFQVLSDSHTVDHFLLCVTILTGRHWHGVDIGHRITCLRSCHRISCCQLKNLCSLHTTRINIVTVHLCCFITVSLSNHS

--------------------------------------------------------------

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Fusion Gene PPI Analysis for RBM26-ATG5


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RBM26-ATG5


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for RBM26-ATG5


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneRBM26C0003165Anthracosis1CTD_human
TgeneATG5C0002871Anemia1CTD_human
TgeneATG5C0019193Hepatitis, Toxic1CTD_human
TgeneATG5C0019209Hepatomegaly1CTD_human
TgeneATG5C0023380Lethargy1CTD_human
TgeneATG5C0024312Lymphopenia1CTD_human
TgeneATG5C0027540Necrosis1CTD_human
TgeneATG5C0860207Drug-Induced Liver Disease1CTD_human
TgeneATG5C0919267ovarian neoplasm1CTD_human
TgeneATG5C1140680Malignant neoplasm of ovary1CTD_human
TgeneATG5C1262477Weight decreased1CTD_human
TgeneATG5C1262760Hepatitis, Drug-Induced1CTD_human
TgeneATG5C3658290Drug-Induced Acute Liver Injury1CTD_human
TgeneATG5C4277682Chemical and Drug Induced Liver Injury1CTD_human
TgeneATG5C4279912Chemically-Induced Liver Toxicity1CTD_human
TgeneATG5C4539808SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 251UNIPROT