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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:RGL1-POU2F1 (FusionGDB2 ID:73284)

Fusion Gene Summary for RGL1-POU2F1

check button Fusion gene summary
Fusion gene informationFusion gene name: RGL1-POU2F1
Fusion gene ID: 73284
HgeneTgene
Gene symbol

RGL1

POU2F1

Gene ID

64333

5451

Gene nameRho GTPase activating protein 9POU class 2 homeobox 1
Synonyms10C|RGL1OCT1|OTF1|oct-1B
Cytomap

12q13.3

1q24.2

Type of geneprotein-codingprotein-coding
Descriptionrho GTPase-activating protein 9rho-type GTPase-activating protein 9POU domain, class 2, transcription factor 1NF-A1OTF-1Octamer-binding transcription factor-1POU class 2 homeobox 1 isoform Oct-1Roct-1octamer-binding protein 1octamer-binding transcription factor 1
Modification date2020032020200320
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000304685, ENST00000536277, 
ENST00000360851, ENST00000539189, 
ENST00000367866, ENST00000452019, 
ENST00000429375, ENST00000367865, 
ENST00000541643, ENST00000420254, 
ENST00000367862, 
Fusion gene scores* DoF score8 X 7 X 5=28010 X 10 X 3=300
# samples 910
** MAII scorelog2(9/280*10)=-1.63742992061529
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/300*10)=-1.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RGL1 [Title/Abstract] AND POU2F1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRGL1(183775619)-POU2F1(167384737), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgenePOU2F1

GO:0045892

negative regulation of transcription, DNA-templated

11891224|11997177

TgenePOU2F1

GO:0045944

positive regulation of transcription by RNA polymerase II

15252056


check buttonFusion gene breakpoints across RGL1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across POU2F1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-DX-AB3A-01ARGL1chr1

183775619

+POU2F1chr1

167384737

+
ChimerDB4SARCTCGA-DX-AB3A-01ARGL1chr1

183775619

-POU2F1chr1

167384737

+


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Fusion Gene ORF analysis for RGL1-POU2F1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000304685ENST00000367866RGL1chr1

183775619

+POU2F1chr1

167384737

+
5CDS-intronENST00000304685ENST00000452019RGL1chr1

183775619

+POU2F1chr1

167384737

+
5CDS-intronENST00000304685ENST00000429375RGL1chr1

183775619

+POU2F1chr1

167384737

+
5CDS-3UTRENST00000304685ENST00000367865RGL1chr1

183775619

+POU2F1chr1

167384737

+
5CDS-3UTRENST00000304685ENST00000541643RGL1chr1

183775619

+POU2F1chr1

167384737

+
5CDS-intronENST00000304685ENST00000420254RGL1chr1

183775619

+POU2F1chr1

167384737

+
5CDS-intronENST00000304685ENST00000367862RGL1chr1

183775619

+POU2F1chr1

167384737

+
intron-3CDSENST00000536277ENST00000367866RGL1chr1

183775619

+POU2F1chr1

167384737

+
intron-intronENST00000536277ENST00000452019RGL1chr1

183775619

+POU2F1chr1

167384737

+
intron-intronENST00000536277ENST00000429375RGL1chr1

183775619

+POU2F1chr1

167384737

+
intron-3UTRENST00000536277ENST00000367865RGL1chr1

183775619

+POU2F1chr1

167384737

+
intron-3UTRENST00000536277ENST00000541643RGL1chr1

183775619

+POU2F1chr1

167384737

+
intron-intronENST00000536277ENST00000420254RGL1chr1

183775619

+POU2F1chr1

167384737

+
intron-intronENST00000536277ENST00000367862RGL1chr1

183775619

+POU2F1chr1

167384737

+
In-frameENST00000360851ENST00000367866RGL1chr1

183775619

+POU2F1chr1

167384737

+
5CDS-intronENST00000360851ENST00000452019RGL1chr1

183775619

+POU2F1chr1

167384737

+
5CDS-intronENST00000360851ENST00000429375RGL1chr1

183775619

+POU2F1chr1

167384737

+
5CDS-3UTRENST00000360851ENST00000367865RGL1chr1

183775619

+POU2F1chr1

167384737

+
5CDS-3UTRENST00000360851ENST00000541643RGL1chr1

183775619

+POU2F1chr1

167384737

+
5CDS-intronENST00000360851ENST00000420254RGL1chr1

183775619

+POU2F1chr1

167384737

+
5CDS-intronENST00000360851ENST00000367862RGL1chr1

183775619

+POU2F1chr1

167384737

+
In-frameENST00000539189ENST00000367866RGL1chr1

183775619

+POU2F1chr1

167384737

+
5CDS-intronENST00000539189ENST00000452019RGL1chr1

183775619

+POU2F1chr1

167384737

+
5CDS-intronENST00000539189ENST00000429375RGL1chr1

183775619

+POU2F1chr1

167384737

+
5CDS-3UTRENST00000539189ENST00000367865RGL1chr1

183775619

+POU2F1chr1

167384737

+
5CDS-3UTRENST00000539189ENST00000541643RGL1chr1

183775619

+POU2F1chr1

167384737

+
5CDS-intronENST00000539189ENST00000420254RGL1chr1

183775619

+POU2F1chr1

167384737

+
5CDS-intronENST00000539189ENST00000367862RGL1chr1

183775619

+POU2F1chr1

167384737

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000304685RGL1chr1183775619+ENST00000367866POU2F1chr1167384737+1253869276167086176
ENST00000360851RGL1chr1183775619+ENST00000367866POU2F1chr1167384737+1216231672406710176
ENST00000539189RGL1chr1183775619+ENST00000367866POU2F1chr1167384737+1212628072046674176

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000304685ENST00000367866RGL1chr1183775619+POU2F1chr1167384737+0.522402940.47759706
ENST00000360851ENST00000367866RGL1chr1183775619+POU2F1chr1167384737+0.5306420.469358
ENST00000539189ENST00000367866RGL1chr1183775619+POU2F1chr1167384737+0.531261270.46873876

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Fusion Genomic Features for RGL1-POU2F1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
RGL1chr1183775619+POU2F1chr1167384736+6.27E-050.9999373
RGL1chr1183775619+POU2F1chr1167384736+6.27E-050.9999373

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for RGL1-POU2F1


check button Go to

FGviewer for the breakpoints of chr1:183775619-chr1:167384737

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePOU2F1chr1:183775619chr1:167384737ENST00000420254017379_4380654.0DNA bindingHomeobox
TgenePOU2F1chr1:183775619chr1:167384737ENST00000420254017280_3540654.0DomainPOU-specific

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRGL1chr1:183775619chr1:167384737ENST00000304685+319541_61381.0804.0Compositional biasNote=Ser-rich
HgeneRGL1chr1:183775619chr1:167384737ENST00000360851+218541_61346.0769.0Compositional biasNote=Ser-rich
HgeneRGL1chr1:183775619chr1:167384737ENST00000304685+319232_50181.0804.0DomainRas-GEF
HgeneRGL1chr1:183775619chr1:167384737ENST00000304685+319648_73581.0804.0DomainRas-associating
HgeneRGL1chr1:183775619chr1:167384737ENST00000304685+31965_19681.0804.0DomainN-terminal Ras-GEF
HgeneRGL1chr1:183775619chr1:167384737ENST00000360851+218232_50146.0769.0DomainRas-GEF
HgeneRGL1chr1:183775619chr1:167384737ENST00000360851+218648_73546.0769.0DomainRas-associating
HgeneRGL1chr1:183775619chr1:167384737ENST00000360851+21865_19646.0769.0DomainN-terminal Ras-GEF
TgenePOU2F1chr1:183775619chr1:167384737ENST000003678621416379_438652.3333333333334756.0DNA bindingHomeobox
TgenePOU2F1chr1:183775619chr1:167384737ENST000004293751315379_438600.3333333333334704.0DNA bindingHomeobox
TgenePOU2F1chr1:183775619chr1:167384737ENST000005416431517379_438640.3333333333334744.0DNA bindingHomeobox
TgenePOU2F1chr1:183775619chr1:167384737ENST000003678621416280_354652.3333333333334756.0DomainPOU-specific
TgenePOU2F1chr1:183775619chr1:167384737ENST000004293751315280_354600.3333333333334704.0DomainPOU-specific
TgenePOU2F1chr1:183775619chr1:167384737ENST000005416431517280_354640.3333333333334744.0DomainPOU-specific


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Fusion Gene Sequence for RGL1-POU2F1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000304685_ENST00000367866_TCGA-DX-AB3A-01A_RGL1_chr1_183775619_+_POU2F1_chr1_167384737_length(transcript)=12538nt_BP=692nt
CTGCGGTCCAGTCTAGGGGGTCTCAGATTGGCGGGGATGGGCAGCAGCGGCAGGTGGCCTTGGCTTTTGCTGCAGCCGTCAACGACCTAT
CATCGGGGTCCTGCGTAAGGTCCGGCTGGCTGGGACTTGGCTGTGGGTGGGATGGACTGGCTGCCGGACCGAGTGCCCTGCAGTTGGTAG
GAGTATGAGGCAGAGTGATGCACACCCGGGCGCCCAGCATCGTTCTAATTGCCGGAGACATTGCCTCAGACTGTGCGCTGCTAGAGGCTG
CGTTCCTGAGCAGGAAGCCCGTTTCCTGGGATTGGAACTACCCTTCTTGGCCAGCGGGAAGTCCCCAAGGACGGAGTCGAAAGGTCAAAT
CTTATCTGTCAGTGCTGTGTGACAGCATCGCAACGGGATCTGCAGAACCTGAACTCGATCCGTAATGCCTCCTGCCTGCCTCTTTCAAGA
TGGAGGTGAAACCTGTGGGAGAACCTACTCAAGAGGTGTCTAAATTCAAACTTTCCACCAAGGTAGAAAGCACGGGACACTGGCTGGTGG
AAGATCATGTTCGAATATGGGAAGTTTTAAAGACAGAGGAGAGCTCGATTCAGGACTGGGGTGAAGAGGTAGAGGAAGGAGCTGTTTACC
ATGTCACCCTCAAAAGAGTCCAGATTCAACAGGCTGCCAATAAAGGAGCAAGATGGCTAGGGCTCTTGCTTCTGGTGGCTCTCTTCCAAT
AACATCACTTGATGCAACTGGGAACCTGGTATTTGCCAATGCGGGAGGAGCCCCCAACATCGTGACTGCCCCTCTGTTCCTGAACCCTCA
GAACCTCTCTCTGCTCACCAGCAACCCTGTTAGCTTGGTCTCTGCCGCCGCAGCATCTGCAGGGAACTCTGCACCTGTAGCCAGCCTTCA
CGCCACCTCCACCTCTGCTGAGTCCATCCAGAACTCTCTCTTCACAGTGGCCTCTGCCAGCGGGGCTGCGTCCACCACCACCACCGCCTC
CAAGGCACAGTGAGCTGGGCAGAGCTGGGCTGCCAGAAGCCTTTTTCACTCTGCAGTGTGATTGGACTGCCAGCCAGGTTAATAAACTGA
AAAATGTGATTGGCTTCCTCTCGCCGTGTTGTGAGGGCAAAGGAGAGAAGGGAGAAAAAAAAAAAAAAACCACACACACCCATACACACA
TACCAGAAAAAGAAAGAAAGGATGGAGACGGAACATTTGCCTAATTTTGTAATAAAACACTGTCTTTTCAGGATTGCTTCATGGATTGGA
GAACTTTCTAACCAAAAATTAAAAAAAAAAAAAAAAAAAGAAACAAAAAAATCAAAAACAAACAAAAATAAGTGAAAGGACTACTTATCA
TTTCCAGCAGTCATGATGACAAGTTAAGGTGGGTTACCAATTCCAATATAGGAAGGGGATTTCTTGTTTGTCTAAATTTCTTTTTTTCTT
AAAAAAAAAAAATCATTTTTATGGGTCTGTTGTACAGGCCATTAAGTCATAACAAGGTGTTTATAATCGTATCAATTGTGTTGGGGGTTC
CTTTCTTAACTGGTACAATTTAGGCAGGCCTGTATTACTGTATTATTATTGTTGTTGTTGTTATTGTTTTATATATATAGTTTGGACATG
TTTATTATCTCTTGCTCCTGGATCCTATTTCAGTGAGCTCCCACACTGTGGGGAGGGAGGGTTTTGGGGTAAGGGGAGACTTCTGTTCTT
AACTGTGGGGAATGTTCTTGCTGGTTTCCTTATCCTTGATGACTCTTACAGAGGTGCTAGAAAATTATTTTCTTTTGCCACTTATGCAAG
AGGCTTGGTGCAGAAGCTGAAGGCAGTGTGTGCAAACACTCCCATTCCACACACGCCCCTTCCCCTCCCCACATCAGGTGGTGCCTTTGG
AGCACTTTTGTGTAGGAAGGAATTCCTGCTGAACTGTAGCTCTCACTCACCCCCAAATCATTGAATGACCCTGAGGCCCAGTTCCTGTGG
TGCAACAGTGCTGCTTTCTGCTACTTTCAATGGGAACAGCTGTACATGTTGCAGGGCAGGATTTGGTTCCCAAGAGCAAAGACTACTGCA
GACACCTGACTTGGTGGTTCTCCTGATTTCTTATCTCCTGAAAAATGCTCCTGCTGTTGGTGTGTTTGTTTGTTTGTTCCATTTTGTGGA
AGTTTTTCATCCAAACTTTAACTAACTTGGCAAAGAAAAAAAACTGACTTACTGAAATTGGGAAACTTTTCCCTTCTTTTATTTTCTAAA
GGAATTCTACTAGACTATTTTCCATTGATAATATATACAAAAGAGGTGTGATGAGAAGGGTATAAGGTTACCACCTTTTCCTCTAGAGAG
CCACAGACTTCCTTTCCACTGGATGGTTTATAAATTCCTCTAACCCTGAGATTCTTCTTGGTTCTCTGACTAAAGGAGGCACTTATTAGC
CGGGCTGGGATCTGTAGAACCTTTGAAGAAGGACTTTGAGCAGGAACTTTGCACACACCTTAAGTGTCTCCTTGGTTTGTTCATGATGCT
CCTGCTAGGTAGGTCTAAATGGCAATACACATCTCTTTATTCAATGTAGAAAGTAATTAGCTCTGTAATTATTTTCAGGGTGTTTGTAGA
CTATATAAATGAGCCCATTGAAAAGGAAGAGTTTGTGAAAGTGGATGAAGAGGAATAAGGGTAACTTGGAGATTAAATTCCTTTTTTTGT
CAGTGTACTGTTGTTATGCCATCTGTACCAAAAAATTTTCCAAAAGACTGGATCACTGCAGTGCAGCTCATCTAAGTTCCCCTTCTTATT
GGAGTTAAAGGTTCCCATTTGGTGGCTGTGGGTGCTTGCTTAAATCTCTGGTGGTCCCAAGACTGCACTTTTTCTCCCTTTCGAGCTGGG
GATGTAGAGAGAACTTACAGGTGATTTTTATTCTGATTGCTTTTGTTTGTGTCCACAAGGGAGCTTGGATTCTGTGTACTTGTCTCTTTC
CCATTGTCCAGTAAGGCAGTAAATACAGACACAATGTGTACTTTTGTGTGTGATTCAAGTGGGAGACAGTCTGTTAAAAGGTCAGAAACA
TTTTAGTCCCCTTTAAAATATTTCTTTTAGTTTATTTCTATCGTGTTTTATTTCACAGATATTTAATTACCACCCCTAAATTTCCTCCTC
TTACCCTTCACCTTCCCTAAAATCCTTCCAAAATCAGTGAACTGCAAGCAGGGAAACTAACAAATGTCCATTCACCCTTTTTGTGTGGTG
TGTTTTTTTATGTTTTGTTTTGTTTTTTAACTAAGCTTGAACCAAAGTCAATTTTTAGCAAGCTGCTGTACTAATGGACTAGTTGATAAC
GTGCAGTTCAGACACATCGAGGAGATAGATGCTACTGACAATTTCTTTTTCATTTGTCTTTATTAATTTTATATGAAAGTTGCTGCTTGT
TTTTAATCTTTTATGTTGGTAAATTGTGATATCCTCTGGGCAGACATTAACTTGATGTTTAACTAGTTTATTAGGTTGGTGTGTAAATAG
AATGACAATGTCAATTACTAATTTCTCTCCTCTCCATTCACTTTTTCTCTGTTGTAGTTAAATTTAATCTTCTATCCTGACTTGACATCT
CTACCTTTAGTCTGTGGAAATGATTTTAGGGCTATCAGTAATGCTGTAGCTGCCCATAATAATGAGTCCCTCCCTTGGGAGTGGTGAAAC
TTAGAAGGAAGGATTCAGGGAGGGAAATGCTGGTACCCAGTATACTGGATTAGAAGTTATAGCATTAATTTCTCAAAATTGCTACCAAAG
GAAGTGTGGAGTCCCAAGGGACTCAAGCTCAGTGAGGTAAGACAAAGGGCAAGGAAAGGCTGTTTGGGTGGTTTTTTTTTCCCCACATAT
GGTTTAGAAAATGATCCCTTTCCCAAACAAAACTCACCAACAGACTTTAATATTAGAAAAGATACTAAGCTTTAAATGTCAATACAGTGG
TCTTTTATTCCCTGCCCTGTCTATATTTTCTACTCAATTTGGGATAAGGGGATTTTATGTGAAGCACTTGATGAGGGTAGACCAGCATAA
AAAATCTGTTTAAAAGAAGAAATAATCTTTAGGAAAAGATAAATCTTTAGATAAAAATAAATTTTTTTCTCTTTTTTTACTTATTTAAAA
ATAAGTTGTGAAATGAAAGGTACATTTACACATGTACACACGAAACACTAATATAGCTTTTTGGTGGTTGTTTAGTTTAAAATCAACTCC
CTATCCATCATCCCTAGATATTCTACTTATCGTATTGCTTCATGAACACCTTAGTCATTTTTTACTTTACGTATATATTTTTTTATCATC
TCAAGAAATGCATTTTGAATTGAATGAACTATCTTCTAAGCTAAGATACTCAAATTTAACTTTTAGCCACCTTATATGGGAGAGCCTGGA
AACTAAAGGGGACCAGGGACCATTTGACCAAAAGAGGTGTTTGGTGGAGTTTCTGCATTTCAAAGAAGAAAGGCCAGATAGGTCATCACA
ATTCATTGTATTATTCTTTTTTTTTCCCCTTAATGTTTATGCAAATTTTATTTTATATTTCTGAATTTGGTTAGCACATACTAAGCCAAA
GACTATTCTAAATGCATTTATAGTGAATACTATGTATGCCCATGGTAATGGGTCCTCCCTAAGGAGTGGTGAATGTAATTGTGTGAATCC
TGCTTATCACAAGTGGTGCAATTTGGTCATAAACTTTATTTATACCCTGTATACATCTGAATAACAGAGCAGAAAGACCTAAAAAAGGGC
TTCTCACAGGAACAATATTACTATGTTGTTCTAAGAAAAAATAAGTTGAGTGCTGTATTAGTTTAAGTGTTTCTAAAGTTCTATAGGCAG
CATTTTAGAATTAAGAATTGTGTATATCCATTAACTGATATAATTCACATGTCCTTTTATTTGTTATCAGAAAGATCAATACTATCCCAA
TTTATTCAACTTGTTACCCAAGAAATGGAACCAAAGGAATCCAACTTTCATTTTGTGTAGAATCATACCTACTTATACTTAATGCTAGCA
CTGTAAGAAATAAGTCTTTTTTGTTTAAAAAAGGGAAGATAAGATTAAAGATTCTTAGTGAGATCATCTTGCCAATTTGTTGTACATCTC
TCATTCATTGTTGGGGGAAAAAAAAGCACAACTATACCTCTTTAATGTTATTTTCTTCCATTATCCCTCATTTATTTGGAAAGATAAGGG
AAACCTTGTCTGTATTATCCAGAAGCACAGATATTTGCTTGACACAATATTTAAATTCAGCCCAATCTTTAACATTAAAAAATTTTCTTT
TTAACTTGCTGGAAAAGTTGGATACATTGGCAAATATAGGGAATTCATGTCTTTTTTTTTTTTTTTTTTCTGGTCTTGCTCTGTTGCCTA
GGCTAGAGTGCAACGGCATGATCTCGGCTCACTGCAACCTCTGCCTCCCGGGTTCAAGCAATTCTCCTGCTTCAGCCTCCCAAGTAGCTG
GGATTACAGGCGCCCACCACCGCACCCGGCTAATTTTTGTATTTTTAGTAGGGACGGGATTTCTCCGTGTTGGCCAGGCTTTTTGAACTC
CTGACCTTAGGTGATCTGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGTATGAGCCACTGTGCCCATCCTCATGTCAATTTTTAA
AGTGATAAATCCTGATATTATACATTGCAATTAGTGTAGAATAAACGCTTGGCTTATAGAACTCTCTGTTCTTAGTCTAAAGCTGTTCCC
AAACCAGGTCATCCTCACGAAACATTCTTGACCAAGAAAAAAGATAAGGTCATTGAGATAGGAAGACAGAGGAAAAGCCTCTTGCTGTTG
TTTCTTCCCAAGAAAGGAGAAGCCCTGCCAGGGAGAAGTCAGTAGTATTGCTGACTCACTGTATCACTGAGTGTAGGGTGTGGTAGCAAG
GAGGAGGCAGGGGATTCACGCTGACAGGTGGCTCTGGCCTGGCTCTTGGGGGGCCTTCTGAAGACCAGTCTGCAGTTTGAGGAAGGGCCC
CAACAATTCATTTGGAGAGCTTGGCCAAATACTTTCTCATTAAATCAGCACCTAAACTTGATGAACTTAAAGTTTGTTTATTAGAGTTGA
AAACATTAAAAGATGACTGATACTAATGGGAGAAAAATACTAAAGACCCAAAATTTAAAATTTTCCAAAATGGACAAGAATTGATGGGTT
AATTTGCTCATAACTGATATGAGTTTGCTTTTATGTGTGTGTGGAAAGCATTTAATGTGTGATGCTGTTCATAGTCCTGGCTATTTGATG
TCATTTTCAGTTTTACAACATTTTGAGGATGACACTTTATAAAATGGTAAATCTTTCTCAGCGTTTACAAACTTGGCTTTTGAGAAGGGA
AAAATCCTCTTTGCTATTTCTGTAAGAAGAATAACTGAGATCAGCTATTATATAGGTTTGCATGGATGGTGTCCACAATACAAATGTAAA
CTTGGACAGGAATAGGATAAATAAATTGCTTTCATCATAAAGGCCAATCATCCATTTCTTAGTCCAAGGAGATTAAATATAAATAGGACA
CCCCTGAGATTTCCAGTAAGGTATTTGAAAGGATTCCACTGGGAGGGCAGGGAATATATTTTTTCTCAGAGCATCCAGTTTGTACCCAGT
TTTCTATATGGTTTGTGAACTGTAGCTTTTAAAAAAAAATTTTGTAGTTTTCTTCTAACCTTATTCATTAAGTAGTTCCTTGTTTTGGCC
CTTCTACTCTTGGCCTTAGCTAAAAGCAGTAAATGTGAGTGAATTTTATGTTGATTATGTCACCTGGATCTCCTTTCCTTCCCTTCTTTT
TCTCATTGAATGGTGGTACCTTAATTTGGGTAACAGCTAGCTTCTGGCACCTTCATAAAATACCTCAGAATAGCTTAGCATTGTTGCAAA
ACTGGTTTTAAACTAAAAACCAAATAAATAAGTGAAAAAATTTTATAAATAGTGGAAATAATTCTAGCTGTAGCATTTAGTTGAACTAAT
GTTTATTATGATCGATAAACAAGATTGATGCTGTATGTATTTGGGATCCTGTTTATAGGTTACAATTTATAGGGTTAGGGAGGGTTGGGT
GGGGGAAGAGGAGATGTTGATTATGTTAGAAGGAAAACATTGCTCGTGTGTGTGTTTGTTTTTTCTTATATCTGTCTTGCCAAAGGAAAC
TTGATTTTCCCTGTGATTGGCTTTGGCCTCTGTGGTCTGGTCTGCAGCAGTGTGTGGTGGCATGCAGGTAACATATGGGGTGTCCAGTAG
GTTCAGGGACCCTGAGGGTGCATTTACATCCCTTCCTATGGTTGCCCATGCCCCCCAGACCCTGCCAACCTCTCCTAATGATTCATTACC
TCTGTACATAGCAAAAGCATAGGCAAAGGATGAATGCGTGAATGCCTGGATGTGCAGTTGAGAAACAGAGGCAGACATAGACATGCACCA
ATTAATTTGGAGCCAAGAGGTGAGTGATTGATGTATCTTAAATCTAGGAAAGTTAAAGTGAAACAGGTTCTTTGTGTTGCCCTCTGTCAA
GTTACTGAATGTTGTGCTAATAACACAACACTTTAAAACCTTACTTACTTTTCTCATACCAAGGCTAGTTCTTTCTAGACCAAAAACACA
AACAGGATAAAAAGCAAACCAAGAAGTTGAAAGCTAACCTGCCCACCTCACCCCTGTGATACAAAGTGTGAACCTTAAGGATTAGTTGGT
GGGATTGAGGAGAGAATTATTCTTGGTGGGAACATGAATGAGAAATGATGCTGGCTTAGGAAAAATCACAAGCCCTTTCTGCCCATACTC
TGGGACAAACTTTCTTGGCTCCCTGAGTTCGGATATAGACTGTATCTCTAGAAAGGCTATTTTTTTAAATAAATGATCCCACAGAACTTA
AGTGGGATTTGGTTTAGATACCAAAGACACTGCTAATGTCATTGCTTATCCTTAAGTTTTCAAAACAGGCAGAGGGAATAGGAGCAAAAA
GCCAAAATTTGGAAAAGCTTTACTTTATCTCTTTCCTTCCCTTTTCCCCTTTTCCCAGTCCCCTGCTTTTTGAAGGAAGTCTTCTTGGTT
ATCCTGGCTTTGGAAAAGAGATTTATTTTGTTTTGCTCTGCTGGCTCTTTAAAGATGGATAGTTGCTCAATCTAGCAGTGATGTTCTTGG
AATTGCTGAGAAATTTGGGGAGGGCAAAAGATAGGGGTAGAATTTTTTCATTATTTCCCTTTATCTAATACTTTTAAATAGAACCAACAC
AGCCTATATGAGTTCAGACAATATTTAGATGTGGTATCTCCATCTGTCTCCTGTAAAAGATAAGAATTTTCAAGAACAGGATTACGTGGA
AAACCAAAAGATCTTCCCTTACTCTCCTATAAATGTTTTGTTCCAAATGTTTTTATATATGGGCTCTAGGGAGTCAGGTAGTTCATTGTT
TCGGTGTACTATTGATAGGACACAGAAAGGGAGAGAGGGTAAAGAAATGTATCACTCTCTGAATATTGCATCAAAAATGATTAGGTTGCA
GAACTTCATGAAAGCTTTACTAATAATCTTATTGTTCTGACATTATGTAAAGGTGGTATTAATATTGTATGACTTGTCAAAGTGCTAGAT
AGGTTTATAAGTAGGTAATAGGGATGTTGAAGATTAGAGCACTTGAAACAGAAGTTCTGGGAAAACAAGGTGTGTGTAATGGAACACCAC
TTTGAGCACAGAAACAAAGGTCCCTTGGACCTGGTAGGGAAGATGTGATTTATGATTGTTTCTGTGTCCCTGTATCTGCCCACCCTGCAC
AGGGCTCCACCACCCAGGGCCACCTTCTGGTTTAAACCCAGGACACTGTCAAAAAGTTAAGACCCCAAAACTAATTTACTGTAAAAAACA
TTGAGGACTGCTGCAAAGTTTTCCCTTGTTTTCTTTGTGTACTTGTTCATCATTGTATAAGTTAGCCACAGCTTCACAAGAGCAGCTTAA
GGCTTCTTTCATAAATTGGCAGTGGCATTGAGTTCTCAAACATTATATCCCAAAGTCTGCAGGCAGACAGCTGGATACAGCGCTGTGTAT
AAATGAGACGTCCAAACACTTGAGTTTCTTAAGATTGGGATCTCTTTCAAATGAAAAAGGACAGAGCCAAGTAGAGAAAAGACTTTGTGC
TCCCACCCAGCCTTAATGAGTCTCATGGTCTAAAAGTATAGGAAGAAATGAAATGCACTTTCAGAAGCTAAAATGACAGTGTCTGCTACA
AAAGGCTGTAGTTGTAGGCAGTCGGGGATGCCATGTCCTTGGTTCCATTCCTGCGTGAGTCTGCAGAAGGCACACACTTTGTAAGAGTAG
AGTGGACTAGTGCCAGCCTGAATAGGTTTAAAACTGCAAACAGTTGGAGAACATGGAACAGGTTGGTGCAGGAAGCCTAAGATTTTGCAA
TCATATTATAACATTGGCTTTTGACAACATAAATGTTGTATCTTCCCTAAGGTCAGGTCGGGGAAAGAAAGACTTCCAGCTTCTTACCTC
TGCGTGCATGGGCACGTGTGCATTGCTCAGTCCGCAGGAGGTCTCACTCCGCAGGAAACGCTCTCCTCCCGCATAAGTCTGTACTTCCAT
CCCCTCATCTGTGGTAGTAGTGAAGGCTAGGTGAGTAAGCGTGGGCTGTTCTACCCACCAGAAGTCCAGGAGCTGTTGTATACCTCATTT
CTAACTCGTGACCGAGTGACTTGCTTTAACTTTCTCGAAATCCTACAGAGTTGCCAAGTCTGCCCTCCCTCCTCAGTCATGTTAAACTCT
GGCCTATAGCATCATGGGACCTGTAGCCTAGGGTGGGACCCCCTAAAGCCTCTGAATGTCGCTGCTTAAAAGCTACTGCAAACTGAGGGC
AAATTGCAATCTTCTATTCCTTTTTGTTGCAAGGGGTCTTCACAGGTCTCTTAACATCTGCTTTCCCTGCCACCCTGCCTTTAGGGGCTG
GCCAGCTATCCACACCCCTAACCCACCCTGTGTTTCTGACAGCTGGCCACACGTCAACTTCTGTACTTGCCTTTTCCTTGGTGGGGTAGA
GGCCAACCCCTTCTCCTCTGAGGCCTCAGGGTTCTGTTTCTTTTCAGGACTTTGGGTAGAAGGGAAGACACCAAAGGCTCCTTTAAGCTG
ACTGCTGCATACACATTTCACTTTTTTTCCTTTGACATGACCAAAAATATCCAAATATTTAAGTTTATTATTATTATTATTATTATTTGA
CAATCTTATATCCAATGGGCTCTCTAGAAGCTGCATCCCCAGCCCTTTCACCTTTTCTTTGAATGTAGTTCCCAACCTTCAATTCCCACC
CCTAATGCTGACAAAAAGCTTAGCCAGGTCATGATACTGCTGCTATAAGCCAGGGGAGGGTGGTTTCTTTGTTTTGTTTTGTTTTGTTTT
GTTTTTCAAATTTCCAGCCAAAACCAAAGATTTCTTAATGATTGTATAAACTCAAAACAAACAAAAGAACCAAAGAAAAGGGAAGTCTTC
AGCATCAGTCCAGTCTGTGGTGTCCTGGCACTTAGAAGAGTGAGGCCAGGGAAGGTGGGGCGGGGGGACCCTCTGACTGGATCAGAAAGG
GCAGGCAAGCTGCTTACCACCTTCCAGGGTCCAGCACAGGTGCATGCCCCTAGCTTTGGCCCTCACAAACTTGTGAGCATGCCCTGAAAC
AAATTGGCATTTCAGATTTTCCAAAACAAAAGTCAAAAAACCCCATCACCACCATCATCCACCCTACACCAACCAGGGTCACTATGGGGA
CTTAGCACAGGGCCTAGGGAGGGTGGGAGCTGCTGCTGGACTGGCCCGAGGACTCCACAGAGTGGGGGACGTTGAAGACACTGGCGCACG
ATTGGCTGCTCTGCTGGGTGCTTTAACCTCTGGGGCTGGGCGAATGCACGCCACGGTGCCCTTCTGAGCCTTTTTTTCTTTTCCTGTACT
GGAACTGCTTGGAAGTGGCTGTCCTGTTTGTGAGAAAACATGCAGAAAGATTATCAAGCTTTTCATTTCTCTTTATTGTAGTTTTCTTTC
CTTTTTGCAGCACCACTGTGCAACTATGCATTGTACTTCACAACCTTTTGTGCTAGGTAGATGCCTGTGACTTTTTAACTTGGGGGGTGG
GGGGATTGCAAATGAAGGAACTTTTTACATGGATCTTTTTAATCTCAGTTGGTTGGGGGAGGGGGGTACTTGGTTCTTGGGTCACACAAG
CTCTATCCCAAAGCAAAATCCAAATGTTAATAATATTAGCCTGATGCAGATACCAAAGATAATTTCTTTCCTGCAGAACCTTAGACTCGT
GTATTAAGTACGATTACCCAGCACTTGCATTAGTCTAACCTCAGTAATTCCAAAGCTTAGATGTATATTTTGGTATATTTCTGGGATATT
AAAAAAAAAATGTCGTTTAACTTCTTGTTTGTTTCAGTGTAATGCTCTTAAAGTCATAGCATGAAAATAATTGAACTGTCCTATTCTTAG
TAGTTTGAAATAATAGTATTTTTGTATGTTTTGGGTGTGTCTATGTATGTATTAACATAACAGTTTTCACTGCCTAGGTGTTCATAATAA
AAAAGAAAATGAAAAAAGTTCTGAGTGTACATAATATTCAATAATAATCTCCCACCAGGTGTCAATTTAGATTGCATATTCCTCATTACT
GTTCCCAACTGGGATTTTGTTTTCTTTTAAAGAGACAGTGATCGTGTTTTTCTAAAGATGTTTTCTTTCTCTCTTTCAATATCTTAACTC
ACTTTTTTTTTCTTCCTTTTTTGTCTTAATTATTAATTCAGGGGTGTTTGTCCACTGTTGTCAAAGGAGGGGCACAAGGGGAATTGGCCC
CCGGCCTCCTAGAACTTTTTGTTTTATGTACTTTAAAATGTGAGTTTGAGTTCTTCTTTGTGGAAACTTAAGATGTGGTGTAAATGATTC
TTTCCAAAATTGTCCAGCAGCTTGAATGAGGCAGTGACAATTCTGAGGTGGTTTATTGGGAGTCCTTCTACATTTCTCTTAGATAACTCT
GCACTCTGGGTGGCTATTGTGTAGCCTTACTGCCCCAGAGTGCCTGTTAGCCAAATATTTCCCCTCTGATAGGAATATTTTCTAAGAATC
AGCTGATAACTTGCGTGCTGGACCTTGTTATCTGTGCCCCTGGGAGACACACGTTTTCTTGGTTTTGAAAACCTGAAACACAGGCAACTT
TACATTTTGGGGAATTAGCTGATGCCTCCTGAAGCCTGAGGAGGTGGCGGGGAATATGAGCGGTGCTGTCTCTCTCAAAAGTGCCCTTTA
GATGATTCCCCCTCCTAGGGCTGCCTGCAGGGGCTGTAGGCTTGGGAAAGATTGTGTAGGTGACAGTGAATCAGAATGAAGTGGTAGATT
TTGTGTAGATGCATTTGTCTGCTGTAATTTTTTATATATATATTAAACTTACTGTAACTGTACAGTTCATTTCTGTTGTAAAACATCATT

>In-frame_ENST00000304685_ENST00000367866_TCGA-DX-AB3A-01A_RGL1_chr1_183775619_+_POU2F1_chr1_167384737_length(amino acids)=176AA_start in transcript=7616_stop in transcript=7086
MRKVSKVLKCCVISTTFSNLTEGNTKNLFHFNFPRFKIHQSLTSWLQINWCMSMSASVSQLHIQAFTHSSFAYAFAMYRGNESLGEVGRV

--------------------------------------------------------------
>In-frame_ENST00000360851_ENST00000367866_TCGA-DX-AB3A-01A_RGL1_chr1_183775619_+_POU2F1_chr1_167384737_length(transcript)=12162nt_BP=316nt
GTGGCCCGAGTCGCGCGCACCGGCGGCGGCGGGGGCAGCGCGGCGCGTGTCTGTGCGCTGCGGTCGCTCGGGACCGGGACCGGGGCGAGG
CGCCGCGGGGCTGAGCCCAGCAGACATTGCGTTGGCCTCCGAGCAGGGCGCATCATGCAGCGTTCGCGCACCGGAGAGAAAACTGAGAAT
GAAATTGCTTTGGCAAGCTAAAATGAGCTCGATTCAGGACTGGGGTGAAGAGGTAGAGGAAGGAGCTGTTTACCATGTCACCCTCAAAAG
AGTCCAGATTCAACAGGCTGCCAATAAAGGAGCAAGATGGCTAGGGCTCTTGCTTCTGGTGGCTCTCTTCCAATAACATCACTTGATGCA
ACTGGGAACCTGGTATTTGCCAATGCGGGAGGAGCCCCCAACATCGTGACTGCCCCTCTGTTCCTGAACCCTCAGAACCTCTCTCTGCTC
ACCAGCAACCCTGTTAGCTTGGTCTCTGCCGCCGCAGCATCTGCAGGGAACTCTGCACCTGTAGCCAGCCTTCACGCCACCTCCACCTCT
GCTGAGTCCATCCAGAACTCTCTCTTCACAGTGGCCTCTGCCAGCGGGGCTGCGTCCACCACCACCACCGCCTCCAAGGCACAGTGAGCT
GGGCAGAGCTGGGCTGCCAGAAGCCTTTTTCACTCTGCAGTGTGATTGGACTGCCAGCCAGGTTAATAAACTGAAAAATGTGATTGGCTT
CCTCTCGCCGTGTTGTGAGGGCAAAGGAGAGAAGGGAGAAAAAAAAAAAAAAACCACACACACCCATACACACATACCAGAAAAAGAAAG
AAAGGATGGAGACGGAACATTTGCCTAATTTTGTAATAAAACACTGTCTTTTCAGGATTGCTTCATGGATTGGAGAACTTTCTAACCAAA
AATTAAAAAAAAAAAAAAAAAAAGAAACAAAAAAATCAAAAACAAACAAAAATAAGTGAAAGGACTACTTATCATTTCCAGCAGTCATGA
TGACAAGTTAAGGTGGGTTACCAATTCCAATATAGGAAGGGGATTTCTTGTTTGTCTAAATTTCTTTTTTTCTTAAAAAAAAAAAATCAT
TTTTATGGGTCTGTTGTACAGGCCATTAAGTCATAACAAGGTGTTTATAATCGTATCAATTGTGTTGGGGGTTCCTTTCTTAACTGGTAC
AATTTAGGCAGGCCTGTATTACTGTATTATTATTGTTGTTGTTGTTATTGTTTTATATATATAGTTTGGACATGTTTATTATCTCTTGCT
CCTGGATCCTATTTCAGTGAGCTCCCACACTGTGGGGAGGGAGGGTTTTGGGGTAAGGGGAGACTTCTGTTCTTAACTGTGGGGAATGTT
CTTGCTGGTTTCCTTATCCTTGATGACTCTTACAGAGGTGCTAGAAAATTATTTTCTTTTGCCACTTATGCAAGAGGCTTGGTGCAGAAG
CTGAAGGCAGTGTGTGCAAACACTCCCATTCCACACACGCCCCTTCCCCTCCCCACATCAGGTGGTGCCTTTGGAGCACTTTTGTGTAGG
AAGGAATTCCTGCTGAACTGTAGCTCTCACTCACCCCCAAATCATTGAATGACCCTGAGGCCCAGTTCCTGTGGTGCAACAGTGCTGCTT
TCTGCTACTTTCAATGGGAACAGCTGTACATGTTGCAGGGCAGGATTTGGTTCCCAAGAGCAAAGACTACTGCAGACACCTGACTTGGTG
GTTCTCCTGATTTCTTATCTCCTGAAAAATGCTCCTGCTGTTGGTGTGTTTGTTTGTTTGTTCCATTTTGTGGAAGTTTTTCATCCAAAC
TTTAACTAACTTGGCAAAGAAAAAAAACTGACTTACTGAAATTGGGAAACTTTTCCCTTCTTTTATTTTCTAAAGGAATTCTACTAGACT
ATTTTCCATTGATAATATATACAAAAGAGGTGTGATGAGAAGGGTATAAGGTTACCACCTTTTCCTCTAGAGAGCCACAGACTTCCTTTC
CACTGGATGGTTTATAAATTCCTCTAACCCTGAGATTCTTCTTGGTTCTCTGACTAAAGGAGGCACTTATTAGCCGGGCTGGGATCTGTA
GAACCTTTGAAGAAGGACTTTGAGCAGGAACTTTGCACACACCTTAAGTGTCTCCTTGGTTTGTTCATGATGCTCCTGCTAGGTAGGTCT
AAATGGCAATACACATCTCTTTATTCAATGTAGAAAGTAATTAGCTCTGTAATTATTTTCAGGGTGTTTGTAGACTATATAAATGAGCCC
ATTGAAAAGGAAGAGTTTGTGAAAGTGGATGAAGAGGAATAAGGGTAACTTGGAGATTAAATTCCTTTTTTTGTCAGTGTACTGTTGTTA
TGCCATCTGTACCAAAAAATTTTCCAAAAGACTGGATCACTGCAGTGCAGCTCATCTAAGTTCCCCTTCTTATTGGAGTTAAAGGTTCCC
ATTTGGTGGCTGTGGGTGCTTGCTTAAATCTCTGGTGGTCCCAAGACTGCACTTTTTCTCCCTTTCGAGCTGGGGATGTAGAGAGAACTT
ACAGGTGATTTTTATTCTGATTGCTTTTGTTTGTGTCCACAAGGGAGCTTGGATTCTGTGTACTTGTCTCTTTCCCATTGTCCAGTAAGG
CAGTAAATACAGACACAATGTGTACTTTTGTGTGTGATTCAAGTGGGAGACAGTCTGTTAAAAGGTCAGAAACATTTTAGTCCCCTTTAA
AATATTTCTTTTAGTTTATTTCTATCGTGTTTTATTTCACAGATATTTAATTACCACCCCTAAATTTCCTCCTCTTACCCTTCACCTTCC
CTAAAATCCTTCCAAAATCAGTGAACTGCAAGCAGGGAAACTAACAAATGTCCATTCACCCTTTTTGTGTGGTGTGTTTTTTTATGTTTT
GTTTTGTTTTTTAACTAAGCTTGAACCAAAGTCAATTTTTAGCAAGCTGCTGTACTAATGGACTAGTTGATAACGTGCAGTTCAGACACA
TCGAGGAGATAGATGCTACTGACAATTTCTTTTTCATTTGTCTTTATTAATTTTATATGAAAGTTGCTGCTTGTTTTTAATCTTTTATGT
TGGTAAATTGTGATATCCTCTGGGCAGACATTAACTTGATGTTTAACTAGTTTATTAGGTTGGTGTGTAAATAGAATGACAATGTCAATT
ACTAATTTCTCTCCTCTCCATTCACTTTTTCTCTGTTGTAGTTAAATTTAATCTTCTATCCTGACTTGACATCTCTACCTTTAGTCTGTG
GAAATGATTTTAGGGCTATCAGTAATGCTGTAGCTGCCCATAATAATGAGTCCCTCCCTTGGGAGTGGTGAAACTTAGAAGGAAGGATTC
AGGGAGGGAAATGCTGGTACCCAGTATACTGGATTAGAAGTTATAGCATTAATTTCTCAAAATTGCTACCAAAGGAAGTGTGGAGTCCCA
AGGGACTCAAGCTCAGTGAGGTAAGACAAAGGGCAAGGAAAGGCTGTTTGGGTGGTTTTTTTTTCCCCACATATGGTTTAGAAAATGATC
CCTTTCCCAAACAAAACTCACCAACAGACTTTAATATTAGAAAAGATACTAAGCTTTAAATGTCAATACAGTGGTCTTTTATTCCCTGCC
CTGTCTATATTTTCTACTCAATTTGGGATAAGGGGATTTTATGTGAAGCACTTGATGAGGGTAGACCAGCATAAAAAATCTGTTTAAAAG
AAGAAATAATCTTTAGGAAAAGATAAATCTTTAGATAAAAATAAATTTTTTTCTCTTTTTTTACTTATTTAAAAATAAGTTGTGAAATGA
AAGGTACATTTACACATGTACACACGAAACACTAATATAGCTTTTTGGTGGTTGTTTAGTTTAAAATCAACTCCCTATCCATCATCCCTA
GATATTCTACTTATCGTATTGCTTCATGAACACCTTAGTCATTTTTTACTTTACGTATATATTTTTTTATCATCTCAAGAAATGCATTTT
GAATTGAATGAACTATCTTCTAAGCTAAGATACTCAAATTTAACTTTTAGCCACCTTATATGGGAGAGCCTGGAAACTAAAGGGGACCAG
GGACCATTTGACCAAAAGAGGTGTTTGGTGGAGTTTCTGCATTTCAAAGAAGAAAGGCCAGATAGGTCATCACAATTCATTGTATTATTC
TTTTTTTTTCCCCTTAATGTTTATGCAAATTTTATTTTATATTTCTGAATTTGGTTAGCACATACTAAGCCAAAGACTATTCTAAATGCA
TTTATAGTGAATACTATGTATGCCCATGGTAATGGGTCCTCCCTAAGGAGTGGTGAATGTAATTGTGTGAATCCTGCTTATCACAAGTGG
TGCAATTTGGTCATAAACTTTATTTATACCCTGTATACATCTGAATAACAGAGCAGAAAGACCTAAAAAAGGGCTTCTCACAGGAACAAT
ATTACTATGTTGTTCTAAGAAAAAATAAGTTGAGTGCTGTATTAGTTTAAGTGTTTCTAAAGTTCTATAGGCAGCATTTTAGAATTAAGA
ATTGTGTATATCCATTAACTGATATAATTCACATGTCCTTTTATTTGTTATCAGAAAGATCAATACTATCCCAATTTATTCAACTTGTTA
CCCAAGAAATGGAACCAAAGGAATCCAACTTTCATTTTGTGTAGAATCATACCTACTTATACTTAATGCTAGCACTGTAAGAAATAAGTC
TTTTTTGTTTAAAAAAGGGAAGATAAGATTAAAGATTCTTAGTGAGATCATCTTGCCAATTTGTTGTACATCTCTCATTCATTGTTGGGG
GAAAAAAAAGCACAACTATACCTCTTTAATGTTATTTTCTTCCATTATCCCTCATTTATTTGGAAAGATAAGGGAAACCTTGTCTGTATT
ATCCAGAAGCACAGATATTTGCTTGACACAATATTTAAATTCAGCCCAATCTTTAACATTAAAAAATTTTCTTTTTAACTTGCTGGAAAA
GTTGGATACATTGGCAAATATAGGGAATTCATGTCTTTTTTTTTTTTTTTTTTCTGGTCTTGCTCTGTTGCCTAGGCTAGAGTGCAACGG
CATGATCTCGGCTCACTGCAACCTCTGCCTCCCGGGTTCAAGCAATTCTCCTGCTTCAGCCTCCCAAGTAGCTGGGATTACAGGCGCCCA
CCACCGCACCCGGCTAATTTTTGTATTTTTAGTAGGGACGGGATTTCTCCGTGTTGGCCAGGCTTTTTGAACTCCTGACCTTAGGTGATC
TGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGTATGAGCCACTGTGCCCATCCTCATGTCAATTTTTAAAGTGATAAATCCTGAT
ATTATACATTGCAATTAGTGTAGAATAAACGCTTGGCTTATAGAACTCTCTGTTCTTAGTCTAAAGCTGTTCCCAAACCAGGTCATCCTC
ACGAAACATTCTTGACCAAGAAAAAAGATAAGGTCATTGAGATAGGAAGACAGAGGAAAAGCCTCTTGCTGTTGTTTCTTCCCAAGAAAG
GAGAAGCCCTGCCAGGGAGAAGTCAGTAGTATTGCTGACTCACTGTATCACTGAGTGTAGGGTGTGGTAGCAAGGAGGAGGCAGGGGATT
CACGCTGACAGGTGGCTCTGGCCTGGCTCTTGGGGGGCCTTCTGAAGACCAGTCTGCAGTTTGAGGAAGGGCCCCAACAATTCATTTGGA
GAGCTTGGCCAAATACTTTCTCATTAAATCAGCACCTAAACTTGATGAACTTAAAGTTTGTTTATTAGAGTTGAAAACATTAAAAGATGA
CTGATACTAATGGGAGAAAAATACTAAAGACCCAAAATTTAAAATTTTCCAAAATGGACAAGAATTGATGGGTTAATTTGCTCATAACTG
ATATGAGTTTGCTTTTATGTGTGTGTGGAAAGCATTTAATGTGTGATGCTGTTCATAGTCCTGGCTATTTGATGTCATTTTCAGTTTTAC
AACATTTTGAGGATGACACTTTATAAAATGGTAAATCTTTCTCAGCGTTTACAAACTTGGCTTTTGAGAAGGGAAAAATCCTCTTTGCTA
TTTCTGTAAGAAGAATAACTGAGATCAGCTATTATATAGGTTTGCATGGATGGTGTCCACAATACAAATGTAAACTTGGACAGGAATAGG
ATAAATAAATTGCTTTCATCATAAAGGCCAATCATCCATTTCTTAGTCCAAGGAGATTAAATATAAATAGGACACCCCTGAGATTTCCAG
TAAGGTATTTGAAAGGATTCCACTGGGAGGGCAGGGAATATATTTTTTCTCAGAGCATCCAGTTTGTACCCAGTTTTCTATATGGTTTGT
GAACTGTAGCTTTTAAAAAAAAATTTTGTAGTTTTCTTCTAACCTTATTCATTAAGTAGTTCCTTGTTTTGGCCCTTCTACTCTTGGCCT
TAGCTAAAAGCAGTAAATGTGAGTGAATTTTATGTTGATTATGTCACCTGGATCTCCTTTCCTTCCCTTCTTTTTCTCATTGAATGGTGG
TACCTTAATTTGGGTAACAGCTAGCTTCTGGCACCTTCATAAAATACCTCAGAATAGCTTAGCATTGTTGCAAAACTGGTTTTAAACTAA
AAACCAAATAAATAAGTGAAAAAATTTTATAAATAGTGGAAATAATTCTAGCTGTAGCATTTAGTTGAACTAATGTTTATTATGATCGAT
AAACAAGATTGATGCTGTATGTATTTGGGATCCTGTTTATAGGTTACAATTTATAGGGTTAGGGAGGGTTGGGTGGGGGAAGAGGAGATG
TTGATTATGTTAGAAGGAAAACATTGCTCGTGTGTGTGTTTGTTTTTTCTTATATCTGTCTTGCCAAAGGAAACTTGATTTTCCCTGTGA
TTGGCTTTGGCCTCTGTGGTCTGGTCTGCAGCAGTGTGTGGTGGCATGCAGGTAACATATGGGGTGTCCAGTAGGTTCAGGGACCCTGAG
GGTGCATTTACATCCCTTCCTATGGTTGCCCATGCCCCCCAGACCCTGCCAACCTCTCCTAATGATTCATTACCTCTGTACATAGCAAAA
GCATAGGCAAAGGATGAATGCGTGAATGCCTGGATGTGCAGTTGAGAAACAGAGGCAGACATAGACATGCACCAATTAATTTGGAGCCAA
GAGGTGAGTGATTGATGTATCTTAAATCTAGGAAAGTTAAAGTGAAACAGGTTCTTTGTGTTGCCCTCTGTCAAGTTACTGAATGTTGTG
CTAATAACACAACACTTTAAAACCTTACTTACTTTTCTCATACCAAGGCTAGTTCTTTCTAGACCAAAAACACAAACAGGATAAAAAGCA
AACCAAGAAGTTGAAAGCTAACCTGCCCACCTCACCCCTGTGATACAAAGTGTGAACCTTAAGGATTAGTTGGTGGGATTGAGGAGAGAA
TTATTCTTGGTGGGAACATGAATGAGAAATGATGCTGGCTTAGGAAAAATCACAAGCCCTTTCTGCCCATACTCTGGGACAAACTTTCTT
GGCTCCCTGAGTTCGGATATAGACTGTATCTCTAGAAAGGCTATTTTTTTAAATAAATGATCCCACAGAACTTAAGTGGGATTTGGTTTA
GATACCAAAGACACTGCTAATGTCATTGCTTATCCTTAAGTTTTCAAAACAGGCAGAGGGAATAGGAGCAAAAAGCCAAAATTTGGAAAA
GCTTTACTTTATCTCTTTCCTTCCCTTTTCCCCTTTTCCCAGTCCCCTGCTTTTTGAAGGAAGTCTTCTTGGTTATCCTGGCTTTGGAAA
AGAGATTTATTTTGTTTTGCTCTGCTGGCTCTTTAAAGATGGATAGTTGCTCAATCTAGCAGTGATGTTCTTGGAATTGCTGAGAAATTT
GGGGAGGGCAAAAGATAGGGGTAGAATTTTTTCATTATTTCCCTTTATCTAATACTTTTAAATAGAACCAACACAGCCTATATGAGTTCA
GACAATATTTAGATGTGGTATCTCCATCTGTCTCCTGTAAAAGATAAGAATTTTCAAGAACAGGATTACGTGGAAAACCAAAAGATCTTC
CCTTACTCTCCTATAAATGTTTTGTTCCAAATGTTTTTATATATGGGCTCTAGGGAGTCAGGTAGTTCATTGTTTCGGTGTACTATTGAT
AGGACACAGAAAGGGAGAGAGGGTAAAGAAATGTATCACTCTCTGAATATTGCATCAAAAATGATTAGGTTGCAGAACTTCATGAAAGCT
TTACTAATAATCTTATTGTTCTGACATTATGTAAAGGTGGTATTAATATTGTATGACTTGTCAAAGTGCTAGATAGGTTTATAAGTAGGT
AATAGGGATGTTGAAGATTAGAGCACTTGAAACAGAAGTTCTGGGAAAACAAGGTGTGTGTAATGGAACACCACTTTGAGCACAGAAACA
AAGGTCCCTTGGACCTGGTAGGGAAGATGTGATTTATGATTGTTTCTGTGTCCCTGTATCTGCCCACCCTGCACAGGGCTCCACCACCCA
GGGCCACCTTCTGGTTTAAACCCAGGACACTGTCAAAAAGTTAAGACCCCAAAACTAATTTACTGTAAAAAACATTGAGGACTGCTGCAA
AGTTTTCCCTTGTTTTCTTTGTGTACTTGTTCATCATTGTATAAGTTAGCCACAGCTTCACAAGAGCAGCTTAAGGCTTCTTTCATAAAT
TGGCAGTGGCATTGAGTTCTCAAACATTATATCCCAAAGTCTGCAGGCAGACAGCTGGATACAGCGCTGTGTATAAATGAGACGTCCAAA
CACTTGAGTTTCTTAAGATTGGGATCTCTTTCAAATGAAAAAGGACAGAGCCAAGTAGAGAAAAGACTTTGTGCTCCCACCCAGCCTTAA
TGAGTCTCATGGTCTAAAAGTATAGGAAGAAATGAAATGCACTTTCAGAAGCTAAAATGACAGTGTCTGCTACAAAAGGCTGTAGTTGTA
GGCAGTCGGGGATGCCATGTCCTTGGTTCCATTCCTGCGTGAGTCTGCAGAAGGCACACACTTTGTAAGAGTAGAGTGGACTAGTGCCAG
CCTGAATAGGTTTAAAACTGCAAACAGTTGGAGAACATGGAACAGGTTGGTGCAGGAAGCCTAAGATTTTGCAATCATATTATAACATTG
GCTTTTGACAACATAAATGTTGTATCTTCCCTAAGGTCAGGTCGGGGAAAGAAAGACTTCCAGCTTCTTACCTCTGCGTGCATGGGCACG
TGTGCATTGCTCAGTCCGCAGGAGGTCTCACTCCGCAGGAAACGCTCTCCTCCCGCATAAGTCTGTACTTCCATCCCCTCATCTGTGGTA
GTAGTGAAGGCTAGGTGAGTAAGCGTGGGCTGTTCTACCCACCAGAAGTCCAGGAGCTGTTGTATACCTCATTTCTAACTCGTGACCGAG
TGACTTGCTTTAACTTTCTCGAAATCCTACAGAGTTGCCAAGTCTGCCCTCCCTCCTCAGTCATGTTAAACTCTGGCCTATAGCATCATG
GGACCTGTAGCCTAGGGTGGGACCCCCTAAAGCCTCTGAATGTCGCTGCTTAAAAGCTACTGCAAACTGAGGGCAAATTGCAATCTTCTA
TTCCTTTTTGTTGCAAGGGGTCTTCACAGGTCTCTTAACATCTGCTTTCCCTGCCACCCTGCCTTTAGGGGCTGGCCAGCTATCCACACC
CCTAACCCACCCTGTGTTTCTGACAGCTGGCCACACGTCAACTTCTGTACTTGCCTTTTCCTTGGTGGGGTAGAGGCCAACCCCTTCTCC
TCTGAGGCCTCAGGGTTCTGTTTCTTTTCAGGACTTTGGGTAGAAGGGAAGACACCAAAGGCTCCTTTAAGCTGACTGCTGCATACACAT
TTCACTTTTTTTCCTTTGACATGACCAAAAATATCCAAATATTTAAGTTTATTATTATTATTATTATTATTTGACAATCTTATATCCAAT
GGGCTCTCTAGAAGCTGCATCCCCAGCCCTTTCACCTTTTCTTTGAATGTAGTTCCCAACCTTCAATTCCCACCCCTAATGCTGACAAAA
AGCTTAGCCAGGTCATGATACTGCTGCTATAAGCCAGGGGAGGGTGGTTTCTTTGTTTTGTTTTGTTTTGTTTTGTTTTTCAAATTTCCA
GCCAAAACCAAAGATTTCTTAATGATTGTATAAACTCAAAACAAACAAAAGAACCAAAGAAAAGGGAAGTCTTCAGCATCAGTCCAGTCT
GTGGTGTCCTGGCACTTAGAAGAGTGAGGCCAGGGAAGGTGGGGCGGGGGGACCCTCTGACTGGATCAGAAAGGGCAGGCAAGCTGCTTA
CCACCTTCCAGGGTCCAGCACAGGTGCATGCCCCTAGCTTTGGCCCTCACAAACTTGTGAGCATGCCCTGAAACAAATTGGCATTTCAGA
TTTTCCAAAACAAAAGTCAAAAAACCCCATCACCACCATCATCCACCCTACACCAACCAGGGTCACTATGGGGACTTAGCACAGGGCCTA
GGGAGGGTGGGAGCTGCTGCTGGACTGGCCCGAGGACTCCACAGAGTGGGGGACGTTGAAGACACTGGCGCACGATTGGCTGCTCTGCTG
GGTGCTTTAACCTCTGGGGCTGGGCGAATGCACGCCACGGTGCCCTTCTGAGCCTTTTTTTCTTTTCCTGTACTGGAACTGCTTGGAAGT
GGCTGTCCTGTTTGTGAGAAAACATGCAGAAAGATTATCAAGCTTTTCATTTCTCTTTATTGTAGTTTTCTTTCCTTTTTGCAGCACCAC
TGTGCAACTATGCATTGTACTTCACAACCTTTTGTGCTAGGTAGATGCCTGTGACTTTTTAACTTGGGGGGTGGGGGGATTGCAAATGAA
GGAACTTTTTACATGGATCTTTTTAATCTCAGTTGGTTGGGGGAGGGGGGTACTTGGTTCTTGGGTCACACAAGCTCTATCCCAAAGCAA
AATCCAAATGTTAATAATATTAGCCTGATGCAGATACCAAAGATAATTTCTTTCCTGCAGAACCTTAGACTCGTGTATTAAGTACGATTA
CCCAGCACTTGCATTAGTCTAACCTCAGTAATTCCAAAGCTTAGATGTATATTTTGGTATATTTCTGGGATATTAAAAAAAAAATGTCGT
TTAACTTCTTGTTTGTTTCAGTGTAATGCTCTTAAAGTCATAGCATGAAAATAATTGAACTGTCCTATTCTTAGTAGTTTGAAATAATAG
TATTTTTGTATGTTTTGGGTGTGTCTATGTATGTATTAACATAACAGTTTTCACTGCCTAGGTGTTCATAATAAAAAAGAAAATGAAAAA
AGTTCTGAGTGTACATAATATTCAATAATAATCTCCCACCAGGTGTCAATTTAGATTGCATATTCCTCATTACTGTTCCCAACTGGGATT
TTGTTTTCTTTTAAAGAGACAGTGATCGTGTTTTTCTAAAGATGTTTTCTTTCTCTCTTTCAATATCTTAACTCACTTTTTTTTTCTTCC
TTTTTTGTCTTAATTATTAATTCAGGGGTGTTTGTCCACTGTTGTCAAAGGAGGGGCACAAGGGGAATTGGCCCCCGGCCTCCTAGAACT
TTTTGTTTTATGTACTTTAAAATGTGAGTTTGAGTTCTTCTTTGTGGAAACTTAAGATGTGGTGTAAATGATTCTTTCCAAAATTGTCCA
GCAGCTTGAATGAGGCAGTGACAATTCTGAGGTGGTTTATTGGGAGTCCTTCTACATTTCTCTTAGATAACTCTGCACTCTGGGTGGCTA
TTGTGTAGCCTTACTGCCCCAGAGTGCCTGTTAGCCAAATATTTCCCCTCTGATAGGAATATTTTCTAAGAATCAGCTGATAACTTGCGT
GCTGGACCTTGTTATCTGTGCCCCTGGGAGACACACGTTTTCTTGGTTTTGAAAACCTGAAACACAGGCAACTTTACATTTTGGGGAATT
AGCTGATGCCTCCTGAAGCCTGAGGAGGTGGCGGGGAATATGAGCGGTGCTGTCTCTCTCAAAAGTGCCCTTTAGATGATTCCCCCTCCT
AGGGCTGCCTGCAGGGGCTGTAGGCTTGGGAAAGATTGTGTAGGTGACAGTGAATCAGAATGAAGTGGTAGATTTTGTGTAGATGCATTT
GTCTGCTGTAATTTTTTATATATATATTAAACTTACTGTAACTGTACAGTTCATTTCTGTTGTAAAACATCATTAAACCATCTTCCAAGT

>In-frame_ENST00000360851_ENST00000367866_TCGA-DX-AB3A-01A_RGL1_chr1_183775619_+_POU2F1_chr1_167384737_length(amino acids)=176AA_start in transcript=7240_stop in transcript=6710
MRKVSKVLKCCVISTTFSNLTEGNTKNLFHFNFPRFKIHQSLTSWLQINWCMSMSASVSQLHIQAFTHSSFAYAFAMYRGNESLGEVGRV

--------------------------------------------------------------
>In-frame_ENST00000539189_ENST00000367866_TCGA-DX-AB3A-01A_RGL1_chr1_183775619_+_POU2F1_chr1_167384737_length(transcript)=12126nt_BP=280nt
AGCGCGGCGCGTGTCTGTGCGCTGCGGTCGCTCGGGACCGGGACCGGGGCGAGGCGCCGCGGGGCTGAGCCCAGCAGACATTGCGTTGGC
CTCCGAGCAGGGCGCATCATGCAGCGTTCGCGCACCGGAGAGAAAACTGAGAATGAAATTGCTTTGGCAAGCTAAAATGAGCTCGATTCA
GGACTGGGGTGAAGAGGTAGAGGAAGGAGCTGTTTACCATGTCACCCTCAAAAGAGTCCAGATTCAACAGGCTGCCAATAAAGGAGCAAG
ATGGCTAGGGCTCTTGCTTCTGGTGGCTCTCTTCCAATAACATCACTTGATGCAACTGGGAACCTGGTATTTGCCAATGCGGGAGGAGCC
CCCAACATCGTGACTGCCCCTCTGTTCCTGAACCCTCAGAACCTCTCTCTGCTCACCAGCAACCCTGTTAGCTTGGTCTCTGCCGCCGCA
GCATCTGCAGGGAACTCTGCACCTGTAGCCAGCCTTCACGCCACCTCCACCTCTGCTGAGTCCATCCAGAACTCTCTCTTCACAGTGGCC
TCTGCCAGCGGGGCTGCGTCCACCACCACCACCGCCTCCAAGGCACAGTGAGCTGGGCAGAGCTGGGCTGCCAGAAGCCTTTTTCACTCT
GCAGTGTGATTGGACTGCCAGCCAGGTTAATAAACTGAAAAATGTGATTGGCTTCCTCTCGCCGTGTTGTGAGGGCAAAGGAGAGAAGGG
AGAAAAAAAAAAAAAAACCACACACACCCATACACACATACCAGAAAAAGAAAGAAAGGATGGAGACGGAACATTTGCCTAATTTTGTAA
TAAAACACTGTCTTTTCAGGATTGCTTCATGGATTGGAGAACTTTCTAACCAAAAATTAAAAAAAAAAAAAAAAAAAGAAACAAAAAAAT
CAAAAACAAACAAAAATAAGTGAAAGGACTACTTATCATTTCCAGCAGTCATGATGACAAGTTAAGGTGGGTTACCAATTCCAATATAGG
AAGGGGATTTCTTGTTTGTCTAAATTTCTTTTTTTCTTAAAAAAAAAAAATCATTTTTATGGGTCTGTTGTACAGGCCATTAAGTCATAA
CAAGGTGTTTATAATCGTATCAATTGTGTTGGGGGTTCCTTTCTTAACTGGTACAATTTAGGCAGGCCTGTATTACTGTATTATTATTGT
TGTTGTTGTTATTGTTTTATATATATAGTTTGGACATGTTTATTATCTCTTGCTCCTGGATCCTATTTCAGTGAGCTCCCACACTGTGGG
GAGGGAGGGTTTTGGGGTAAGGGGAGACTTCTGTTCTTAACTGTGGGGAATGTTCTTGCTGGTTTCCTTATCCTTGATGACTCTTACAGA
GGTGCTAGAAAATTATTTTCTTTTGCCACTTATGCAAGAGGCTTGGTGCAGAAGCTGAAGGCAGTGTGTGCAAACACTCCCATTCCACAC
ACGCCCCTTCCCCTCCCCACATCAGGTGGTGCCTTTGGAGCACTTTTGTGTAGGAAGGAATTCCTGCTGAACTGTAGCTCTCACTCACCC
CCAAATCATTGAATGACCCTGAGGCCCAGTTCCTGTGGTGCAACAGTGCTGCTTTCTGCTACTTTCAATGGGAACAGCTGTACATGTTGC
AGGGCAGGATTTGGTTCCCAAGAGCAAAGACTACTGCAGACACCTGACTTGGTGGTTCTCCTGATTTCTTATCTCCTGAAAAATGCTCCT
GCTGTTGGTGTGTTTGTTTGTTTGTTCCATTTTGTGGAAGTTTTTCATCCAAACTTTAACTAACTTGGCAAAGAAAAAAAACTGACTTAC
TGAAATTGGGAAACTTTTCCCTTCTTTTATTTTCTAAAGGAATTCTACTAGACTATTTTCCATTGATAATATATACAAAAGAGGTGTGAT
GAGAAGGGTATAAGGTTACCACCTTTTCCTCTAGAGAGCCACAGACTTCCTTTCCACTGGATGGTTTATAAATTCCTCTAACCCTGAGAT
TCTTCTTGGTTCTCTGACTAAAGGAGGCACTTATTAGCCGGGCTGGGATCTGTAGAACCTTTGAAGAAGGACTTTGAGCAGGAACTTTGC
ACACACCTTAAGTGTCTCCTTGGTTTGTTCATGATGCTCCTGCTAGGTAGGTCTAAATGGCAATACACATCTCTTTATTCAATGTAGAAA
GTAATTAGCTCTGTAATTATTTTCAGGGTGTTTGTAGACTATATAAATGAGCCCATTGAAAAGGAAGAGTTTGTGAAAGTGGATGAAGAG
GAATAAGGGTAACTTGGAGATTAAATTCCTTTTTTTGTCAGTGTACTGTTGTTATGCCATCTGTACCAAAAAATTTTCCAAAAGACTGGA
TCACTGCAGTGCAGCTCATCTAAGTTCCCCTTCTTATTGGAGTTAAAGGTTCCCATTTGGTGGCTGTGGGTGCTTGCTTAAATCTCTGGT
GGTCCCAAGACTGCACTTTTTCTCCCTTTCGAGCTGGGGATGTAGAGAGAACTTACAGGTGATTTTTATTCTGATTGCTTTTGTTTGTGT
CCACAAGGGAGCTTGGATTCTGTGTACTTGTCTCTTTCCCATTGTCCAGTAAGGCAGTAAATACAGACACAATGTGTACTTTTGTGTGTG
ATTCAAGTGGGAGACAGTCTGTTAAAAGGTCAGAAACATTTTAGTCCCCTTTAAAATATTTCTTTTAGTTTATTTCTATCGTGTTTTATT
TCACAGATATTTAATTACCACCCCTAAATTTCCTCCTCTTACCCTTCACCTTCCCTAAAATCCTTCCAAAATCAGTGAACTGCAAGCAGG
GAAACTAACAAATGTCCATTCACCCTTTTTGTGTGGTGTGTTTTTTTATGTTTTGTTTTGTTTTTTAACTAAGCTTGAACCAAAGTCAAT
TTTTAGCAAGCTGCTGTACTAATGGACTAGTTGATAACGTGCAGTTCAGACACATCGAGGAGATAGATGCTACTGACAATTTCTTTTTCA
TTTGTCTTTATTAATTTTATATGAAAGTTGCTGCTTGTTTTTAATCTTTTATGTTGGTAAATTGTGATATCCTCTGGGCAGACATTAACT
TGATGTTTAACTAGTTTATTAGGTTGGTGTGTAAATAGAATGACAATGTCAATTACTAATTTCTCTCCTCTCCATTCACTTTTTCTCTGT
TGTAGTTAAATTTAATCTTCTATCCTGACTTGACATCTCTACCTTTAGTCTGTGGAAATGATTTTAGGGCTATCAGTAATGCTGTAGCTG
CCCATAATAATGAGTCCCTCCCTTGGGAGTGGTGAAACTTAGAAGGAAGGATTCAGGGAGGGAAATGCTGGTACCCAGTATACTGGATTA
GAAGTTATAGCATTAATTTCTCAAAATTGCTACCAAAGGAAGTGTGGAGTCCCAAGGGACTCAAGCTCAGTGAGGTAAGACAAAGGGCAA
GGAAAGGCTGTTTGGGTGGTTTTTTTTTCCCCACATATGGTTTAGAAAATGATCCCTTTCCCAAACAAAACTCACCAACAGACTTTAATA
TTAGAAAAGATACTAAGCTTTAAATGTCAATACAGTGGTCTTTTATTCCCTGCCCTGTCTATATTTTCTACTCAATTTGGGATAAGGGGA
TTTTATGTGAAGCACTTGATGAGGGTAGACCAGCATAAAAAATCTGTTTAAAAGAAGAAATAATCTTTAGGAAAAGATAAATCTTTAGAT
AAAAATAAATTTTTTTCTCTTTTTTTACTTATTTAAAAATAAGTTGTGAAATGAAAGGTACATTTACACATGTACACACGAAACACTAAT
ATAGCTTTTTGGTGGTTGTTTAGTTTAAAATCAACTCCCTATCCATCATCCCTAGATATTCTACTTATCGTATTGCTTCATGAACACCTT
AGTCATTTTTTACTTTACGTATATATTTTTTTATCATCTCAAGAAATGCATTTTGAATTGAATGAACTATCTTCTAAGCTAAGATACTCA
AATTTAACTTTTAGCCACCTTATATGGGAGAGCCTGGAAACTAAAGGGGACCAGGGACCATTTGACCAAAAGAGGTGTTTGGTGGAGTTT
CTGCATTTCAAAGAAGAAAGGCCAGATAGGTCATCACAATTCATTGTATTATTCTTTTTTTTTCCCCTTAATGTTTATGCAAATTTTATT
TTATATTTCTGAATTTGGTTAGCACATACTAAGCCAAAGACTATTCTAAATGCATTTATAGTGAATACTATGTATGCCCATGGTAATGGG
TCCTCCCTAAGGAGTGGTGAATGTAATTGTGTGAATCCTGCTTATCACAAGTGGTGCAATTTGGTCATAAACTTTATTTATACCCTGTAT
ACATCTGAATAACAGAGCAGAAAGACCTAAAAAAGGGCTTCTCACAGGAACAATATTACTATGTTGTTCTAAGAAAAAATAAGTTGAGTG
CTGTATTAGTTTAAGTGTTTCTAAAGTTCTATAGGCAGCATTTTAGAATTAAGAATTGTGTATATCCATTAACTGATATAATTCACATGT
CCTTTTATTTGTTATCAGAAAGATCAATACTATCCCAATTTATTCAACTTGTTACCCAAGAAATGGAACCAAAGGAATCCAACTTTCATT
TTGTGTAGAATCATACCTACTTATACTTAATGCTAGCACTGTAAGAAATAAGTCTTTTTTGTTTAAAAAAGGGAAGATAAGATTAAAGAT
TCTTAGTGAGATCATCTTGCCAATTTGTTGTACATCTCTCATTCATTGTTGGGGGAAAAAAAAGCACAACTATACCTCTTTAATGTTATT
TTCTTCCATTATCCCTCATTTATTTGGAAAGATAAGGGAAACCTTGTCTGTATTATCCAGAAGCACAGATATTTGCTTGACACAATATTT
AAATTCAGCCCAATCTTTAACATTAAAAAATTTTCTTTTTAACTTGCTGGAAAAGTTGGATACATTGGCAAATATAGGGAATTCATGTCT
TTTTTTTTTTTTTTTTTCTGGTCTTGCTCTGTTGCCTAGGCTAGAGTGCAACGGCATGATCTCGGCTCACTGCAACCTCTGCCTCCCGGG
TTCAAGCAATTCTCCTGCTTCAGCCTCCCAAGTAGCTGGGATTACAGGCGCCCACCACCGCACCCGGCTAATTTTTGTATTTTTAGTAGG
GACGGGATTTCTCCGTGTTGGCCAGGCTTTTTGAACTCCTGACCTTAGGTGATCTGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAG
GTATGAGCCACTGTGCCCATCCTCATGTCAATTTTTAAAGTGATAAATCCTGATATTATACATTGCAATTAGTGTAGAATAAACGCTTGG
CTTATAGAACTCTCTGTTCTTAGTCTAAAGCTGTTCCCAAACCAGGTCATCCTCACGAAACATTCTTGACCAAGAAAAAAGATAAGGTCA
TTGAGATAGGAAGACAGAGGAAAAGCCTCTTGCTGTTGTTTCTTCCCAAGAAAGGAGAAGCCCTGCCAGGGAGAAGTCAGTAGTATTGCT
GACTCACTGTATCACTGAGTGTAGGGTGTGGTAGCAAGGAGGAGGCAGGGGATTCACGCTGACAGGTGGCTCTGGCCTGGCTCTTGGGGG
GCCTTCTGAAGACCAGTCTGCAGTTTGAGGAAGGGCCCCAACAATTCATTTGGAGAGCTTGGCCAAATACTTTCTCATTAAATCAGCACC
TAAACTTGATGAACTTAAAGTTTGTTTATTAGAGTTGAAAACATTAAAAGATGACTGATACTAATGGGAGAAAAATACTAAAGACCCAAA
ATTTAAAATTTTCCAAAATGGACAAGAATTGATGGGTTAATTTGCTCATAACTGATATGAGTTTGCTTTTATGTGTGTGTGGAAAGCATT
TAATGTGTGATGCTGTTCATAGTCCTGGCTATTTGATGTCATTTTCAGTTTTACAACATTTTGAGGATGACACTTTATAAAATGGTAAAT
CTTTCTCAGCGTTTACAAACTTGGCTTTTGAGAAGGGAAAAATCCTCTTTGCTATTTCTGTAAGAAGAATAACTGAGATCAGCTATTATA
TAGGTTTGCATGGATGGTGTCCACAATACAAATGTAAACTTGGACAGGAATAGGATAAATAAATTGCTTTCATCATAAAGGCCAATCATC
CATTTCTTAGTCCAAGGAGATTAAATATAAATAGGACACCCCTGAGATTTCCAGTAAGGTATTTGAAAGGATTCCACTGGGAGGGCAGGG
AATATATTTTTTCTCAGAGCATCCAGTTTGTACCCAGTTTTCTATATGGTTTGTGAACTGTAGCTTTTAAAAAAAAATTTTGTAGTTTTC
TTCTAACCTTATTCATTAAGTAGTTCCTTGTTTTGGCCCTTCTACTCTTGGCCTTAGCTAAAAGCAGTAAATGTGAGTGAATTTTATGTT
GATTATGTCACCTGGATCTCCTTTCCTTCCCTTCTTTTTCTCATTGAATGGTGGTACCTTAATTTGGGTAACAGCTAGCTTCTGGCACCT
TCATAAAATACCTCAGAATAGCTTAGCATTGTTGCAAAACTGGTTTTAAACTAAAAACCAAATAAATAAGTGAAAAAATTTTATAAATAG
TGGAAATAATTCTAGCTGTAGCATTTAGTTGAACTAATGTTTATTATGATCGATAAACAAGATTGATGCTGTATGTATTTGGGATCCTGT
TTATAGGTTACAATTTATAGGGTTAGGGAGGGTTGGGTGGGGGAAGAGGAGATGTTGATTATGTTAGAAGGAAAACATTGCTCGTGTGTG
TGTTTGTTTTTTCTTATATCTGTCTTGCCAAAGGAAACTTGATTTTCCCTGTGATTGGCTTTGGCCTCTGTGGTCTGGTCTGCAGCAGTG
TGTGGTGGCATGCAGGTAACATATGGGGTGTCCAGTAGGTTCAGGGACCCTGAGGGTGCATTTACATCCCTTCCTATGGTTGCCCATGCC
CCCCAGACCCTGCCAACCTCTCCTAATGATTCATTACCTCTGTACATAGCAAAAGCATAGGCAAAGGATGAATGCGTGAATGCCTGGATG
TGCAGTTGAGAAACAGAGGCAGACATAGACATGCACCAATTAATTTGGAGCCAAGAGGTGAGTGATTGATGTATCTTAAATCTAGGAAAG
TTAAAGTGAAACAGGTTCTTTGTGTTGCCCTCTGTCAAGTTACTGAATGTTGTGCTAATAACACAACACTTTAAAACCTTACTTACTTTT
CTCATACCAAGGCTAGTTCTTTCTAGACCAAAAACACAAACAGGATAAAAAGCAAACCAAGAAGTTGAAAGCTAACCTGCCCACCTCACC
CCTGTGATACAAAGTGTGAACCTTAAGGATTAGTTGGTGGGATTGAGGAGAGAATTATTCTTGGTGGGAACATGAATGAGAAATGATGCT
GGCTTAGGAAAAATCACAAGCCCTTTCTGCCCATACTCTGGGACAAACTTTCTTGGCTCCCTGAGTTCGGATATAGACTGTATCTCTAGA
AAGGCTATTTTTTTAAATAAATGATCCCACAGAACTTAAGTGGGATTTGGTTTAGATACCAAAGACACTGCTAATGTCATTGCTTATCCT
TAAGTTTTCAAAACAGGCAGAGGGAATAGGAGCAAAAAGCCAAAATTTGGAAAAGCTTTACTTTATCTCTTTCCTTCCCTTTTCCCCTTT
TCCCAGTCCCCTGCTTTTTGAAGGAAGTCTTCTTGGTTATCCTGGCTTTGGAAAAGAGATTTATTTTGTTTTGCTCTGCTGGCTCTTTAA
AGATGGATAGTTGCTCAATCTAGCAGTGATGTTCTTGGAATTGCTGAGAAATTTGGGGAGGGCAAAAGATAGGGGTAGAATTTTTTCATT
ATTTCCCTTTATCTAATACTTTTAAATAGAACCAACACAGCCTATATGAGTTCAGACAATATTTAGATGTGGTATCTCCATCTGTCTCCT
GTAAAAGATAAGAATTTTCAAGAACAGGATTACGTGGAAAACCAAAAGATCTTCCCTTACTCTCCTATAAATGTTTTGTTCCAAATGTTT
TTATATATGGGCTCTAGGGAGTCAGGTAGTTCATTGTTTCGGTGTACTATTGATAGGACACAGAAAGGGAGAGAGGGTAAAGAAATGTAT
CACTCTCTGAATATTGCATCAAAAATGATTAGGTTGCAGAACTTCATGAAAGCTTTACTAATAATCTTATTGTTCTGACATTATGTAAAG
GTGGTATTAATATTGTATGACTTGTCAAAGTGCTAGATAGGTTTATAAGTAGGTAATAGGGATGTTGAAGATTAGAGCACTTGAAACAGA
AGTTCTGGGAAAACAAGGTGTGTGTAATGGAACACCACTTTGAGCACAGAAACAAAGGTCCCTTGGACCTGGTAGGGAAGATGTGATTTA
TGATTGTTTCTGTGTCCCTGTATCTGCCCACCCTGCACAGGGCTCCACCACCCAGGGCCACCTTCTGGTTTAAACCCAGGACACTGTCAA
AAAGTTAAGACCCCAAAACTAATTTACTGTAAAAAACATTGAGGACTGCTGCAAAGTTTTCCCTTGTTTTCTTTGTGTACTTGTTCATCA
TTGTATAAGTTAGCCACAGCTTCACAAGAGCAGCTTAAGGCTTCTTTCATAAATTGGCAGTGGCATTGAGTTCTCAAACATTATATCCCA
AAGTCTGCAGGCAGACAGCTGGATACAGCGCTGTGTATAAATGAGACGTCCAAACACTTGAGTTTCTTAAGATTGGGATCTCTTTCAAAT
GAAAAAGGACAGAGCCAAGTAGAGAAAAGACTTTGTGCTCCCACCCAGCCTTAATGAGTCTCATGGTCTAAAAGTATAGGAAGAAATGAA
ATGCACTTTCAGAAGCTAAAATGACAGTGTCTGCTACAAAAGGCTGTAGTTGTAGGCAGTCGGGGATGCCATGTCCTTGGTTCCATTCCT
GCGTGAGTCTGCAGAAGGCACACACTTTGTAAGAGTAGAGTGGACTAGTGCCAGCCTGAATAGGTTTAAAACTGCAAACAGTTGGAGAAC
ATGGAACAGGTTGGTGCAGGAAGCCTAAGATTTTGCAATCATATTATAACATTGGCTTTTGACAACATAAATGTTGTATCTTCCCTAAGG
TCAGGTCGGGGAAAGAAAGACTTCCAGCTTCTTACCTCTGCGTGCATGGGCACGTGTGCATTGCTCAGTCCGCAGGAGGTCTCACTCCGC
AGGAAACGCTCTCCTCCCGCATAAGTCTGTACTTCCATCCCCTCATCTGTGGTAGTAGTGAAGGCTAGGTGAGTAAGCGTGGGCTGTTCT
ACCCACCAGAAGTCCAGGAGCTGTTGTATACCTCATTTCTAACTCGTGACCGAGTGACTTGCTTTAACTTTCTCGAAATCCTACAGAGTT
GCCAAGTCTGCCCTCCCTCCTCAGTCATGTTAAACTCTGGCCTATAGCATCATGGGACCTGTAGCCTAGGGTGGGACCCCCTAAAGCCTC
TGAATGTCGCTGCTTAAAAGCTACTGCAAACTGAGGGCAAATTGCAATCTTCTATTCCTTTTTGTTGCAAGGGGTCTTCACAGGTCTCTT
AACATCTGCTTTCCCTGCCACCCTGCCTTTAGGGGCTGGCCAGCTATCCACACCCCTAACCCACCCTGTGTTTCTGACAGCTGGCCACAC
GTCAACTTCTGTACTTGCCTTTTCCTTGGTGGGGTAGAGGCCAACCCCTTCTCCTCTGAGGCCTCAGGGTTCTGTTTCTTTTCAGGACTT
TGGGTAGAAGGGAAGACACCAAAGGCTCCTTTAAGCTGACTGCTGCATACACATTTCACTTTTTTTCCTTTGACATGACCAAAAATATCC
AAATATTTAAGTTTATTATTATTATTATTATTATTTGACAATCTTATATCCAATGGGCTCTCTAGAAGCTGCATCCCCAGCCCTTTCACC
TTTTCTTTGAATGTAGTTCCCAACCTTCAATTCCCACCCCTAATGCTGACAAAAAGCTTAGCCAGGTCATGATACTGCTGCTATAAGCCA
GGGGAGGGTGGTTTCTTTGTTTTGTTTTGTTTTGTTTTGTTTTTCAAATTTCCAGCCAAAACCAAAGATTTCTTAATGATTGTATAAACT
CAAAACAAACAAAAGAACCAAAGAAAAGGGAAGTCTTCAGCATCAGTCCAGTCTGTGGTGTCCTGGCACTTAGAAGAGTGAGGCCAGGGA
AGGTGGGGCGGGGGGACCCTCTGACTGGATCAGAAAGGGCAGGCAAGCTGCTTACCACCTTCCAGGGTCCAGCACAGGTGCATGCCCCTA
GCTTTGGCCCTCACAAACTTGTGAGCATGCCCTGAAACAAATTGGCATTTCAGATTTTCCAAAACAAAAGTCAAAAAACCCCATCACCAC
CATCATCCACCCTACACCAACCAGGGTCACTATGGGGACTTAGCACAGGGCCTAGGGAGGGTGGGAGCTGCTGCTGGACTGGCCCGAGGA
CTCCACAGAGTGGGGGACGTTGAAGACACTGGCGCACGATTGGCTGCTCTGCTGGGTGCTTTAACCTCTGGGGCTGGGCGAATGCACGCC
ACGGTGCCCTTCTGAGCCTTTTTTTCTTTTCCTGTACTGGAACTGCTTGGAAGTGGCTGTCCTGTTTGTGAGAAAACATGCAGAAAGATT
ATCAAGCTTTTCATTTCTCTTTATTGTAGTTTTCTTTCCTTTTTGCAGCACCACTGTGCAACTATGCATTGTACTTCACAACCTTTTGTG
CTAGGTAGATGCCTGTGACTTTTTAACTTGGGGGGTGGGGGGATTGCAAATGAAGGAACTTTTTACATGGATCTTTTTAATCTCAGTTGG
TTGGGGGAGGGGGGTACTTGGTTCTTGGGTCACACAAGCTCTATCCCAAAGCAAAATCCAAATGTTAATAATATTAGCCTGATGCAGATA
CCAAAGATAATTTCTTTCCTGCAGAACCTTAGACTCGTGTATTAAGTACGATTACCCAGCACTTGCATTAGTCTAACCTCAGTAATTCCA
AAGCTTAGATGTATATTTTGGTATATTTCTGGGATATTAAAAAAAAAATGTCGTTTAACTTCTTGTTTGTTTCAGTGTAATGCTCTTAAA
GTCATAGCATGAAAATAATTGAACTGTCCTATTCTTAGTAGTTTGAAATAATAGTATTTTTGTATGTTTTGGGTGTGTCTATGTATGTAT
TAACATAACAGTTTTCACTGCCTAGGTGTTCATAATAAAAAAGAAAATGAAAAAAGTTCTGAGTGTACATAATATTCAATAATAATCTCC
CACCAGGTGTCAATTTAGATTGCATATTCCTCATTACTGTTCCCAACTGGGATTTTGTTTTCTTTTAAAGAGACAGTGATCGTGTTTTTC
TAAAGATGTTTTCTTTCTCTCTTTCAATATCTTAACTCACTTTTTTTTTCTTCCTTTTTTGTCTTAATTATTAATTCAGGGGTGTTTGTC
CACTGTTGTCAAAGGAGGGGCACAAGGGGAATTGGCCCCCGGCCTCCTAGAACTTTTTGTTTTATGTACTTTAAAATGTGAGTTTGAGTT
CTTCTTTGTGGAAACTTAAGATGTGGTGTAAATGATTCTTTCCAAAATTGTCCAGCAGCTTGAATGAGGCAGTGACAATTCTGAGGTGGT
TTATTGGGAGTCCTTCTACATTTCTCTTAGATAACTCTGCACTCTGGGTGGCTATTGTGTAGCCTTACTGCCCCAGAGTGCCTGTTAGCC
AAATATTTCCCCTCTGATAGGAATATTTTCTAAGAATCAGCTGATAACTTGCGTGCTGGACCTTGTTATCTGTGCCCCTGGGAGACACAC
GTTTTCTTGGTTTTGAAAACCTGAAACACAGGCAACTTTACATTTTGGGGAATTAGCTGATGCCTCCTGAAGCCTGAGGAGGTGGCGGGG
AATATGAGCGGTGCTGTCTCTCTCAAAAGTGCCCTTTAGATGATTCCCCCTCCTAGGGCTGCCTGCAGGGGCTGTAGGCTTGGGAAAGAT
TGTGTAGGTGACAGTGAATCAGAATGAAGTGGTAGATTTTGTGTAGATGCATTTGTCTGCTGTAATTTTTTATATATATATTAAACTTAC

>In-frame_ENST00000539189_ENST00000367866_TCGA-DX-AB3A-01A_RGL1_chr1_183775619_+_POU2F1_chr1_167384737_length(amino acids)=176AA_start in transcript=7204_stop in transcript=6674
MRKVSKVLKCCVISTTFSNLTEGNTKNLFHFNFPRFKIHQSLTSWLQINWCMSMSASVSQLHIQAFTHSSFAYAFAMYRGNESLGEVGRV

--------------------------------------------------------------

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Fusion Gene PPI Analysis for RGL1-POU2F1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RGL1-POU2F1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for RGL1-POU2F1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource