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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:RGPD5-TMEM18 (FusionGDB2 ID:73324)

Fusion Gene Summary for RGPD5-TMEM18

check button Fusion gene summary
Fusion gene informationFusion gene name: RGPD5-TMEM18
Fusion gene ID: 73324
HgeneTgene
Gene symbol

RGPD5

TMEM18

Gene ID

84220

129787

Gene nameRANBP2 like and GRIP domain containing 5transmembrane protein 18
SynonymsBS-63|BS63|HEL161|RGP5lncND
Cytomap

2q13

2p25.3

Type of geneprotein-codingprotein-coding
DescriptionRANBP2-like and GRIP domain-containing protein 5/6RANBP2-like and GRIP domain-containing protein 5epididymis luminal protein 161ran-binding protein 2-like 1ran-binding protein 2-like 1/2ranBP2-like 1ranBP2-like 1/2ranBP2L1sperm membrane protein BStransmembrane protein 18
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000393283, ENST00000272454, 
ENST00000016946, ENST00000495582, 
ENST00000281017, ENST00000355654, 
ENST00000405941, 
Fusion gene scores* DoF score5 X 4 X 5=1002 X 2 X 2=8
# samples 52
** MAII scorelog2(5/100*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(2/8*10)=1.32192809488736
Context

PubMed: RGPD5 [Title/Abstract] AND TMEM18 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRGPD5(110552114)-TMEM18(675630), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneTMEM18

GO:0016477

cell migration

18559506


check buttonFusion gene breakpoints across RGPD5 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across TMEM18 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-HC-7078RGPD5chr2

110552114

+TMEM18chr2

675630

-
ChimerDB4PRADTCGA-HC-7078RGPD5chr2

110552114

+TMEM18chr2

675630

-


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Fusion Gene ORF analysis for RGPD5-TMEM18

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000393283ENST00000281017RGPD5chr2

110552114

+TMEM18chr2

675630

-
In-frameENST00000393283ENST00000355654RGPD5chr2

110552114

+TMEM18chr2

675630

-
In-frameENST00000393283ENST00000405941RGPD5chr2

110552114

+TMEM18chr2

675630

-
In-frameENST00000272454ENST00000281017RGPD5chr2

110552114

+TMEM18chr2

675630

-
In-frameENST00000272454ENST00000355654RGPD5chr2

110552114

+TMEM18chr2

675630

-
In-frameENST00000272454ENST00000405941RGPD5chr2

110552114

+TMEM18chr2

675630

-
In-frameENST00000016946ENST00000281017RGPD5chr2

110552114

+TMEM18chr2

675630

-
In-frameENST00000016946ENST00000355654RGPD5chr2

110552114

+TMEM18chr2

675630

-
In-frameENST00000016946ENST00000405941RGPD5chr2

110552114

+TMEM18chr2

675630

-
intron-3CDSENST00000495582ENST00000281017RGPD5chr2

110552114

+TMEM18chr2

675630

-
intron-3CDSENST00000495582ENST00000355654RGPD5chr2

110552114

+TMEM18chr2

675630

-
intron-3CDSENST00000495582ENST00000405941RGPD5chr2

110552114

+TMEM18chr2

675630

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000393283RGPD5chr2110552114+ENST00000281017TMEM18chr2675630-3216605434970178
ENST00000393283RGPD5chr2110552114+ENST00000355654TMEM18chr2675630-1362605434970178
ENST00000393283RGPD5chr2110552114+ENST00000405941TMEM18chr2675630-1128605434970178
ENST00000272454RGPD5chr2110552114+ENST00000281017TMEM18chr2675630-287526493629178
ENST00000272454RGPD5chr2110552114+ENST00000355654TMEM18chr2675630-102126493629178
ENST00000272454RGPD5chr2110552114+ENST00000405941TMEM18chr2675630-78726493629178
ENST00000016946RGPD5chr2110552114+ENST00000281017TMEM18chr2675630-284123059595178
ENST00000016946RGPD5chr2110552114+ENST00000355654TMEM18chr2675630-98723059595178
ENST00000016946RGPD5chr2110552114+ENST00000405941TMEM18chr2675630-75323059595178

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000393283ENST00000281017RGPD5chr2110552114+TMEM18chr2675630-0.0173635370.98263645
ENST00000393283ENST00000355654RGPD5chr2110552114+TMEM18chr2675630-0.042005810.95799416
ENST00000393283ENST00000405941RGPD5chr2110552114+TMEM18chr2675630-0.0367799480.96322
ENST00000272454ENST00000281017RGPD5chr2110552114+TMEM18chr2675630-0.0152617810.98473823
ENST00000272454ENST00000355654RGPD5chr2110552114+TMEM18chr2675630-0.0363785960.96362144
ENST00000272454ENST00000405941RGPD5chr2110552114+TMEM18chr2675630-0.0264920850.97350794
ENST00000016946ENST00000281017RGPD5chr2110552114+TMEM18chr2675630-0.0143103110.98568976
ENST00000016946ENST00000355654RGPD5chr2110552114+TMEM18chr2675630-0.028405250.97159475
ENST00000016946ENST00000405941RGPD5chr2110552114+TMEM18chr2675630-0.0211827160.9788173

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Fusion Genomic Features for RGPD5-TMEM18


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for RGPD5-TMEM18


check button Go to

FGviewer for the breakpoints of chr2:110552114-chr2:675630

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTMEM18chr2:110552114chr2:675630ENST0000028101705116_14019.0141.0Coiled coilOntology_term=ECO:0000255
TgeneTMEM18chr2:110552114chr2:675630ENST0000035565405116_1406.0128.0Coiled coilOntology_term=ECO:0000255
TgeneTMEM18chr2:110552114chr2:675630ENST0000028101705130_13819.0141.0MotifNote=Nuclear localization signal
TgeneTMEM18chr2:110552114chr2:675630ENST0000035565405130_1386.0128.0MotifNote=Nuclear localization signal
TgeneTMEM18chr2:110552114chr2:675630ENST0000028101705113_14019.0141.0RegionNote=DNA-binding
TgeneTMEM18chr2:110552114chr2:675630ENST0000035565405113_1406.0128.0RegionNote=DNA-binding
TgeneTMEM18chr2:110552114chr2:675630ENST000002810170547_5219.0141.0Topological domainNuclear
TgeneTMEM18chr2:110552114chr2:675630ENST000002810170574_9119.0141.0Topological domainPerinuclear space
TgeneTMEM18chr2:110552114chr2:675630ENST000003556540547_526.0128.0Topological domainNuclear
TgeneTMEM18chr2:110552114chr2:675630ENST000003556540574_916.0128.0Topological domainPerinuclear space
TgeneTMEM18chr2:110552114chr2:675630ENST000002810170526_4619.0141.0TransmembraneHelical
TgeneTMEM18chr2:110552114chr2:675630ENST000002810170553_7319.0141.0TransmembraneHelical
TgeneTMEM18chr2:110552114chr2:675630ENST000002810170592_11219.0141.0TransmembraneHelical
TgeneTMEM18chr2:110552114chr2:675630ENST000003556540526_466.0128.0TransmembraneHelical
TgeneTMEM18chr2:110552114chr2:675630ENST000003556540553_736.0128.0TransmembraneHelical
TgeneTMEM18chr2:110552114chr2:675630ENST000003556540592_1126.0128.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRGPD5chr2:110552114chr2:675630ENST00000016946+1231261_126624.01766.0Compositional biasNote=Poly-Ser
HgeneRGPD5chr2:110552114chr2:675630ENST00000272454+1191261_126624.0905.0Compositional biasNote=Poly-Ser
HgeneRGPD5chr2:110552114chr2:675630ENST00000393283+2201261_126624.0905.0Compositional biasNote=Poly-Ser
HgeneRGPD5chr2:110552114chr2:675630ENST00000016946+1231036_117224.01766.0DomainRanBD1 1
HgeneRGPD5chr2:110552114chr2:675630ENST00000016946+1231333_146924.01766.0DomainRanBD1 2
HgeneRGPD5chr2:110552114chr2:675630ENST00000016946+1231702_175224.01766.0DomainGRIP
HgeneRGPD5chr2:110552114chr2:675630ENST00000272454+1191036_117224.0905.0DomainRanBD1 1
HgeneRGPD5chr2:110552114chr2:675630ENST00000272454+1191333_146924.0905.0DomainRanBD1 2
HgeneRGPD5chr2:110552114chr2:675630ENST00000272454+1191702_175224.0905.0DomainGRIP
HgeneRGPD5chr2:110552114chr2:675630ENST00000393283+2201036_117224.0905.0DomainRanBD1 1
HgeneRGPD5chr2:110552114chr2:675630ENST00000393283+2201333_146924.0905.0DomainRanBD1 2
HgeneRGPD5chr2:110552114chr2:675630ENST00000393283+2201702_175224.0905.0DomainGRIP
HgeneRGPD5chr2:110552114chr2:675630ENST00000016946+12326_5924.01766.0RepeatNote=TPR 1
HgeneRGPD5chr2:110552114chr2:675630ENST00000016946+12360_9324.01766.0RepeatNote=TPR 2
HgeneRGPD5chr2:110552114chr2:675630ENST00000016946+123648_68124.01766.0RepeatNote=TPR 3
HgeneRGPD5chr2:110552114chr2:675630ENST00000272454+11926_5924.0905.0RepeatNote=TPR 1
HgeneRGPD5chr2:110552114chr2:675630ENST00000272454+11960_9324.0905.0RepeatNote=TPR 2
HgeneRGPD5chr2:110552114chr2:675630ENST00000272454+119648_68124.0905.0RepeatNote=TPR 3
HgeneRGPD5chr2:110552114chr2:675630ENST00000393283+22026_5924.0905.0RepeatNote=TPR 1
HgeneRGPD5chr2:110552114chr2:675630ENST00000393283+22060_9324.0905.0RepeatNote=TPR 2
HgeneRGPD5chr2:110552114chr2:675630ENST00000393283+220648_68124.0905.0RepeatNote=TPR 3
TgeneTMEM18chr2:110552114chr2:675630ENST00000281017051_2519.0141.0Topological domainPerinuclear space
TgeneTMEM18chr2:110552114chr2:675630ENST00000355654051_256.0128.0Topological domainPerinuclear space


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Fusion Gene Sequence for RGPD5-TMEM18


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000393283_ENST00000281017_TCGA-HC-7078_RGPD5_chr2_110552114_+_TMEM18_chr2_675630_length(transcript)=3216nt_BP=605nt
ATAAACCCCAGGGCTCATTCTTGAGCTGCTCCTGCATAGATCTCGTCCTGTTCAACACACCAAAGATTGACAGCTGAACTGAGAGACCAT
CACCCACAGACACAACTGGCCACTGGGTGGTGCACAAGTCAGACAGAACTGAATAGTCCTGTGAAGACTCTGGACACTGAACTGACTTTG
GAACCAGACTGCAGAATGGAGGGGTGGGAACTTGTGGCTTGAACCTAATCAGGTTTCATTAAGGTTTTCTATAGATAAGATCATGTCAAG
ACACCCTCAGACCACAGGGCGGCGCCACGAGCCCGGCCGAGTGCAGCTGGAGCGCCGACGTCGCCGAGGATACACAGTGCTGAGGCAGAA
CGCAGGTTCGTCACAGTGGGCCTCCGTGGGCGGCGCCGCACGCTCGTCACAGTGGGCCTCCGCCGGCTACGCCGCTGCTTCAGTGGCTTG
CAGGCACTTTCCTCTTGGAAGTGGCGACTGCTGCGGGGCTGAGCGGTGCTCGCACGCGTCTCGGGAGCCAGGTTGGCGGCGCGATGAGGC
GCAGCAAGGCCGATGTGGAGCGGTACGTCGCCTCGGTGCTGGGTCTCACCCCGTCGCCTCGACAGCAGACGGACTGGACTGAGCCCTGGC
TCATGGGGCTGGCCACCTTCCACGCGCTCTGCGTGCTCCTCACCTGCTTGTCCTCCCGAAGCTACAGACTACAGATCGGGCACTTTCTGT
GTCTAGTCATCTTAGTCTACTGTGCTGAATACATCAATGAGGCGGCTGCGATGAACTGGAGATTATTTTCGAAATACCAGTATTTCGACT
CCAGGGGGATGTTCATTTCTATAGTATTTTCAGCCCCACTGCTGGTGAATGCCATGATCATTGTGGTTATGTGGGTATGGAAGACTTTGA
ATGTGATGACTGACCTGAAGAATGCACAAGAGAGAAGAAAGGAAAAGAAAAGGAGAAGGAAAGAAGACTGAGGGGCAGCAGCTGCTTGGA
GTTTGCGTCCTTCCCGTCCACCCAGTGCAGCTCCCAGTGCTGCAGTGTGCGTGGCGTGGGCATCCTTCCAGCTGACTCATGGTTTGAAAA
ACCGTTGTTTTATTTAAATATCCACAGTGGTAGGGCACACACTGAAGTTGGCTTTTCAGCCAGCACTGAATGTATCCATCAGGACATGCG
TCTTCAGGTGCCTGATCTTTGTAGTCAGGCTGTGGGAACGGTCTCTGCAGAGCTTCATAACTGGGAATTTGATTTGAAGAAGTCCATGTC
ATATGTGTAACTAGTACTAATTATAAATATAAAATACACAATATAAAATATGAAACTCAATAATAAACAGTGCCACCTGTACATGGGCAC
CATGCCCTCCTCCTCGTGCTGTGTTTTCTAGTGCATGCCACAGTTCGCAGTAGAGGGTGTTTTCACCTTCCAAGACATGGGGCAAAGTTT
GGAGACACCTGGTTGTCACTGGAGGGGGTGGTGCTCCTGGCTTCTCCTGTGGAGCCCGGGGTGATGCATAAAATCCTGTGTGCCTGGGTC
AGCCGCATCACAGACAATGACTTGACATGAAATGTCAGCTGTGCTGGGGCAGAGAGACCTTGGAAGGAAGCTCTTGGAAAATACGTTGTA
TCTCAGTTTGATGAACCAATTCACAAGAGGCTAGGCCCTCTCTAGCAAAGTTATGGGCTGCTTTACTGAAAACAGAATGGAAGCCCTGAA
GTCAACACTCCATGGAGAAGCGTGTCTTTCCTAATGTCCTGGTGTTCTGTTGATTTAGGTGCTTGGGAACACAATGCTCCCAGTTCTGTT
AGGACAGGCATACTGTTACTTTGCAATATCCACTTTATAAAATAGCTCCTGCCCAGTGGCTCTTGGTTCCTGTCAAATGTGGACCTGTAG
TTTAAGAATGACAGGTGGTTAGAGACCCAGATATTTAAAAATAGGTGTTCAATAAGGGAATACTGATTGTGCATTGTATCTGGATAGCAT
GCCTAATTGTGCATTTCTGAAAGTTACCAATTCAAAATGTAATTGGAACAGTTATCTTTGATTAGACAAGCCTGGGAAGAGAATGTTGAG
GTGCAGAGCTCACCAGCCAAGTTCATGCCCCTCTCGGGCCTTTGTGGCTGAGAAGTGGGACAGAAAGATGATTAAGGTAATGTGTCCTCC
CTGTAGCATTGTCCAGGGCCGTTGTGTAGATATTTGACTTCACTGACAGAAAAGAAACCAGGGAGTTTGTAGAGACTGTGCATTTTTAGT
ATAACATTTTCACCATCTGATATGGTTTGGCTTTGTGTCCCCACCCAAATTGCATCTCAAATTGTAATCCCCATGTGTCAAGGGAGGGAC
CTGATGGGAGGTGATGGGATCATGGGGGTGGTTTCCCCTATGTTGTTATCATAATAGAGAGGGAGTTCTCACAAGATCTGCTGGTTTTAA
AGACAGCAGTTTCCCCTGCTGTCACTGTCTCTCTCCTGCTGCCTTGTGAAGAAGGTGCTTGTTTCTCCCTCTGCCATGATTGTAAGTTTC
CCGAGGCCTCCCCGGCCATGTGGAACTGAGTCAATTAAACTTCTTGTTTATAAAGTAATCCAGGTCTCAGGTAGTATCTTTATAGCAGTG
TGAGAACAGACTAATTAAACATCTATATGTTATTTGGACTTAATATGGGGCCGTGTGATTGAATCTCAGTTTGCCTGTGATAAAGTAGTG
TAACAGTATTGCTAGCTTTGCATGAATTTGATGCTGATGACATGTCAGTGTGAAACCATGACGTGTGGTCTTTGATTTTCATTCTGCATG
TGTGTGTCTGTGTTTTGGAACAGTTATATTTTGGTTTTGTAAAAACAACCTTCACTTTATTTTTAACTGTGTAGTAAGTTTATATTCAAT
GCCTTAAAGTGCATTGTTAACAATTGTCTTGATATGTTGTCCTCATTTTAGGGAAAGTCATAGAAGCCAAAATGATCAGCAGTTGAGTAA
TTTACGAAAGCACAGGTGCAATCCCACTTTAAAGCACTGGGGGTTGCACAGAGCACACTGGTTTCAGGCTCCATAAATGTGGATGACTCA
CTGGAGAGCTTCATCTGTTTAAGTAGAACAAATGTTTTTACTCTACTGATAAAGTACAGGAAAGGAGGTTTGGGATCAAAATTATTTTTC

>In-frame_ENST00000393283_ENST00000281017_TCGA-HC-7078_RGPD5_chr2_110552114_+_TMEM18_chr2_675630_length(amino acids)=178AA_start in transcript=434_stop in transcript=970
MLQWLAGTFLLEVATAAGLSGARTRLGSQVGGAMRRSKADVERYVASVLGLTPSPRQQTDWTEPWLMGLATFHALCVLLTCLSSRSYRLQ

--------------------------------------------------------------
>In-frame_ENST00000393283_ENST00000355654_TCGA-HC-7078_RGPD5_chr2_110552114_+_TMEM18_chr2_675630_length(transcript)=1362nt_BP=605nt
ATAAACCCCAGGGCTCATTCTTGAGCTGCTCCTGCATAGATCTCGTCCTGTTCAACACACCAAAGATTGACAGCTGAACTGAGAGACCAT
CACCCACAGACACAACTGGCCACTGGGTGGTGCACAAGTCAGACAGAACTGAATAGTCCTGTGAAGACTCTGGACACTGAACTGACTTTG
GAACCAGACTGCAGAATGGAGGGGTGGGAACTTGTGGCTTGAACCTAATCAGGTTTCATTAAGGTTTTCTATAGATAAGATCATGTCAAG
ACACCCTCAGACCACAGGGCGGCGCCACGAGCCCGGCCGAGTGCAGCTGGAGCGCCGACGTCGCCGAGGATACACAGTGCTGAGGCAGAA
CGCAGGTTCGTCACAGTGGGCCTCCGTGGGCGGCGCCGCACGCTCGTCACAGTGGGCCTCCGCCGGCTACGCCGCTGCTTCAGTGGCTTG
CAGGCACTTTCCTCTTGGAAGTGGCGACTGCTGCGGGGCTGAGCGGTGCTCGCACGCGTCTCGGGAGCCAGGTTGGCGGCGCGATGAGGC
GCAGCAAGGCCGATGTGGAGCGGTACGTCGCCTCGGTGCTGGGTCTCACCCCGTCGCCTCGACAGCAGACGGACTGGACTGAGCCCTGGC
TCATGGGGCTGGCCACCTTCCACGCGCTCTGCGTGCTCCTCACCTGCTTGTCCTCCCGAAGCTACAGACTACAGATCGGGCACTTTCTGT
GTCTAGTCATCTTAGTCTACTGTGCTGAATACATCAATGAGGCGGCTGCGATGAACTGGAGATTATTTTCGAAATACCAGTATTTCGACT
CCAGGGGGATGTTCATTTCTATAGTATTTTCAGCCCCACTGCTGGTGAATGCCATGATCATTGTGGTTATGTGGGTATGGAAGACTTTGA
ATGTGATGACTGACCTGAAGAATGCACAAGAGAGAAGAAAGGAAAAGAAAAGGAGAAGGAAAGAAGACTGAGGGGCAGCAGCTGCTTGGA
GTTTGCGTCCTTCCCGTCCACCCAGTGCAGCTCCCAGTGCTGCAGTGTGCGTGGCGTGGGCATCCTTCCAGCTGACTCATGGTTTGAAAA
ACCGTTGTTTTATTTAAATATCCACAGTGGTAGGGCACACACTGAAGTTGGCTTTTCAGCCAGCACTGAATGTATCCATCAGGACATGCG
TCTTCAGGTGCCTGATCTTTGTAGTCAGGCTGTGGGAACGGTCTCTGCAGAGCTTCATAACTGGGAATTTGATTTGAAGAAGTCCATGTC
ATATGTGTAACTAGTACTAATTATAAATATAAAATACACAATATAAAATATGAAACTCAATAATAAACAGTGCCACCTGTACATGGGCAC

>In-frame_ENST00000393283_ENST00000355654_TCGA-HC-7078_RGPD5_chr2_110552114_+_TMEM18_chr2_675630_length(amino acids)=178AA_start in transcript=434_stop in transcript=970
MLQWLAGTFLLEVATAAGLSGARTRLGSQVGGAMRRSKADVERYVASVLGLTPSPRQQTDWTEPWLMGLATFHALCVLLTCLSSRSYRLQ

--------------------------------------------------------------
>In-frame_ENST00000393283_ENST00000405941_TCGA-HC-7078_RGPD5_chr2_110552114_+_TMEM18_chr2_675630_length(transcript)=1128nt_BP=605nt
ATAAACCCCAGGGCTCATTCTTGAGCTGCTCCTGCATAGATCTCGTCCTGTTCAACACACCAAAGATTGACAGCTGAACTGAGAGACCAT
CACCCACAGACACAACTGGCCACTGGGTGGTGCACAAGTCAGACAGAACTGAATAGTCCTGTGAAGACTCTGGACACTGAACTGACTTTG
GAACCAGACTGCAGAATGGAGGGGTGGGAACTTGTGGCTTGAACCTAATCAGGTTTCATTAAGGTTTTCTATAGATAAGATCATGTCAAG
ACACCCTCAGACCACAGGGCGGCGCCACGAGCCCGGCCGAGTGCAGCTGGAGCGCCGACGTCGCCGAGGATACACAGTGCTGAGGCAGAA
CGCAGGTTCGTCACAGTGGGCCTCCGTGGGCGGCGCCGCACGCTCGTCACAGTGGGCCTCCGCCGGCTACGCCGCTGCTTCAGTGGCTTG
CAGGCACTTTCCTCTTGGAAGTGGCGACTGCTGCGGGGCTGAGCGGTGCTCGCACGCGTCTCGGGAGCCAGGTTGGCGGCGCGATGAGGC
GCAGCAAGGCCGATGTGGAGCGGTACGTCGCCTCGGTGCTGGGTCTCACCCCGTCGCCTCGACAGCAGACGGACTGGACTGAGCCCTGGC
TCATGGGGCTGGCCACCTTCCACGCGCTCTGCGTGCTCCTCACCTGCTTGTCCTCCCGAAGCTACAGACTACAGATCGGGCACTTTCTGT
GTCTAGTCATCTTAGTCTACTGTGCTGAATACATCAATGAGGCGGCTGCGATGAACTGGAGATTATTTTCGAAATACCAGTATTTCGACT
CCAGGGGGATGTTCATTTCTATAGTATTTTCAGCCCCACTGCTGGTGAATGCCATGATCATTGTGGTTATGTGGGTATGGAAGACTTTGA
ATGTGATGACTGACCTGAAGAATGCACAAGAGAGAAGAAAGGAAAAGAAAAGGAGAAGGAAAGAAGACTGAGGGGCAGCAGCTGCTTGGA
GTTTGCGTCCTTCCCGTCCACCCAGTGCAGCTCCCAGTGCTGCAGTGTGCGTGGCGTGGGCATCCTTCCAGCTGACTCATGGTTTGAAAA

>In-frame_ENST00000393283_ENST00000405941_TCGA-HC-7078_RGPD5_chr2_110552114_+_TMEM18_chr2_675630_length(amino acids)=178AA_start in transcript=434_stop in transcript=970
MLQWLAGTFLLEVATAAGLSGARTRLGSQVGGAMRRSKADVERYVASVLGLTPSPRQQTDWTEPWLMGLATFHALCVLLTCLSSRSYRLQ

--------------------------------------------------------------
>In-frame_ENST00000272454_ENST00000281017_TCGA-HC-7078_RGPD5_chr2_110552114_+_TMEM18_chr2_675630_length(transcript)=2875nt_BP=264nt
ACACAGTGCTGAGGCAGAACGCAGGTTCGTCACAGTGGGCCTCCGTGGGCGGCGCCGCACGCTCGTCACAGTGGGCCTCCGCCGGCTACG
CCGCTGCTTCAGTGGCTTGCAGGCACTTTCCTCTTGGAAGTGGCGACTGCTGCGGGGCTGAGCGGTGCTCGCACGCGTCTCGGGAGCCAG
GTTGGCGGCGCGATGAGGCGCAGCAAGGCCGATGTGGAGCGGTACGTCGCCTCGGTGCTGGGTCTCACCCCGTCGCCTCGACAGCAGACG
GACTGGACTGAGCCCTGGCTCATGGGGCTGGCCACCTTCCACGCGCTCTGCGTGCTCCTCACCTGCTTGTCCTCCCGAAGCTACAGACTA
CAGATCGGGCACTTTCTGTGTCTAGTCATCTTAGTCTACTGTGCTGAATACATCAATGAGGCGGCTGCGATGAACTGGAGATTATTTTCG
AAATACCAGTATTTCGACTCCAGGGGGATGTTCATTTCTATAGTATTTTCAGCCCCACTGCTGGTGAATGCCATGATCATTGTGGTTATG
TGGGTATGGAAGACTTTGAATGTGATGACTGACCTGAAGAATGCACAAGAGAGAAGAAAGGAAAAGAAAAGGAGAAGGAAAGAAGACTGA
GGGGCAGCAGCTGCTTGGAGTTTGCGTCCTTCCCGTCCACCCAGTGCAGCTCCCAGTGCTGCAGTGTGCGTGGCGTGGGCATCCTTCCAG
CTGACTCATGGTTTGAAAAACCGTTGTTTTATTTAAATATCCACAGTGGTAGGGCACACACTGAAGTTGGCTTTTCAGCCAGCACTGAAT
GTATCCATCAGGACATGCGTCTTCAGGTGCCTGATCTTTGTAGTCAGGCTGTGGGAACGGTCTCTGCAGAGCTTCATAACTGGGAATTTG
ATTTGAAGAAGTCCATGTCATATGTGTAACTAGTACTAATTATAAATATAAAATACACAATATAAAATATGAAACTCAATAATAAACAGT
GCCACCTGTACATGGGCACCATGCCCTCCTCCTCGTGCTGTGTTTTCTAGTGCATGCCACAGTTCGCAGTAGAGGGTGTTTTCACCTTCC
AAGACATGGGGCAAAGTTTGGAGACACCTGGTTGTCACTGGAGGGGGTGGTGCTCCTGGCTTCTCCTGTGGAGCCCGGGGTGATGCATAA
AATCCTGTGTGCCTGGGTCAGCCGCATCACAGACAATGACTTGACATGAAATGTCAGCTGTGCTGGGGCAGAGAGACCTTGGAAGGAAGC
TCTTGGAAAATACGTTGTATCTCAGTTTGATGAACCAATTCACAAGAGGCTAGGCCCTCTCTAGCAAAGTTATGGGCTGCTTTACTGAAA
ACAGAATGGAAGCCCTGAAGTCAACACTCCATGGAGAAGCGTGTCTTTCCTAATGTCCTGGTGTTCTGTTGATTTAGGTGCTTGGGAACA
CAATGCTCCCAGTTCTGTTAGGACAGGCATACTGTTACTTTGCAATATCCACTTTATAAAATAGCTCCTGCCCAGTGGCTCTTGGTTCCT
GTCAAATGTGGACCTGTAGTTTAAGAATGACAGGTGGTTAGAGACCCAGATATTTAAAAATAGGTGTTCAATAAGGGAATACTGATTGTG
CATTGTATCTGGATAGCATGCCTAATTGTGCATTTCTGAAAGTTACCAATTCAAAATGTAATTGGAACAGTTATCTTTGATTAGACAAGC
CTGGGAAGAGAATGTTGAGGTGCAGAGCTCACCAGCCAAGTTCATGCCCCTCTCGGGCCTTTGTGGCTGAGAAGTGGGACAGAAAGATGA
TTAAGGTAATGTGTCCTCCCTGTAGCATTGTCCAGGGCCGTTGTGTAGATATTTGACTTCACTGACAGAAAAGAAACCAGGGAGTTTGTA
GAGACTGTGCATTTTTAGTATAACATTTTCACCATCTGATATGGTTTGGCTTTGTGTCCCCACCCAAATTGCATCTCAAATTGTAATCCC
CATGTGTCAAGGGAGGGACCTGATGGGAGGTGATGGGATCATGGGGGTGGTTTCCCCTATGTTGTTATCATAATAGAGAGGGAGTTCTCA
CAAGATCTGCTGGTTTTAAAGACAGCAGTTTCCCCTGCTGTCACTGTCTCTCTCCTGCTGCCTTGTGAAGAAGGTGCTTGTTTCTCCCTC
TGCCATGATTGTAAGTTTCCCGAGGCCTCCCCGGCCATGTGGAACTGAGTCAATTAAACTTCTTGTTTATAAAGTAATCCAGGTCTCAGG
TAGTATCTTTATAGCAGTGTGAGAACAGACTAATTAAACATCTATATGTTATTTGGACTTAATATGGGGCCGTGTGATTGAATCTCAGTT
TGCCTGTGATAAAGTAGTGTAACAGTATTGCTAGCTTTGCATGAATTTGATGCTGATGACATGTCAGTGTGAAACCATGACGTGTGGTCT
TTGATTTTCATTCTGCATGTGTGTGTCTGTGTTTTGGAACAGTTATATTTTGGTTTTGTAAAAACAACCTTCACTTTATTTTTAACTGTG
TAGTAAGTTTATATTCAATGCCTTAAAGTGCATTGTTAACAATTGTCTTGATATGTTGTCCTCATTTTAGGGAAAGTCATAGAAGCCAAA
ATGATCAGCAGTTGAGTAATTTACGAAAGCACAGGTGCAATCCCACTTTAAAGCACTGGGGGTTGCACAGAGCACACTGGTTTCAGGCTC
CATAAATGTGGATGACTCACTGGAGAGCTTCATCTGTTTAAGTAGAACAAATGTTTTTACTCTACTGATAAAGTACAGGAAAGGAGGTTT

>In-frame_ENST00000272454_ENST00000281017_TCGA-HC-7078_RGPD5_chr2_110552114_+_TMEM18_chr2_675630_length(amino acids)=178AA_start in transcript=93_stop in transcript=629
MLQWLAGTFLLEVATAAGLSGARTRLGSQVGGAMRRSKADVERYVASVLGLTPSPRQQTDWTEPWLMGLATFHALCVLLTCLSSRSYRLQ

--------------------------------------------------------------
>In-frame_ENST00000272454_ENST00000355654_TCGA-HC-7078_RGPD5_chr2_110552114_+_TMEM18_chr2_675630_length(transcript)=1021nt_BP=264nt
ACACAGTGCTGAGGCAGAACGCAGGTTCGTCACAGTGGGCCTCCGTGGGCGGCGCCGCACGCTCGTCACAGTGGGCCTCCGCCGGCTACG
CCGCTGCTTCAGTGGCTTGCAGGCACTTTCCTCTTGGAAGTGGCGACTGCTGCGGGGCTGAGCGGTGCTCGCACGCGTCTCGGGAGCCAG
GTTGGCGGCGCGATGAGGCGCAGCAAGGCCGATGTGGAGCGGTACGTCGCCTCGGTGCTGGGTCTCACCCCGTCGCCTCGACAGCAGACG
GACTGGACTGAGCCCTGGCTCATGGGGCTGGCCACCTTCCACGCGCTCTGCGTGCTCCTCACCTGCTTGTCCTCCCGAAGCTACAGACTA
CAGATCGGGCACTTTCTGTGTCTAGTCATCTTAGTCTACTGTGCTGAATACATCAATGAGGCGGCTGCGATGAACTGGAGATTATTTTCG
AAATACCAGTATTTCGACTCCAGGGGGATGTTCATTTCTATAGTATTTTCAGCCCCACTGCTGGTGAATGCCATGATCATTGTGGTTATG
TGGGTATGGAAGACTTTGAATGTGATGACTGACCTGAAGAATGCACAAGAGAGAAGAAAGGAAAAGAAAAGGAGAAGGAAAGAAGACTGA
GGGGCAGCAGCTGCTTGGAGTTTGCGTCCTTCCCGTCCACCCAGTGCAGCTCCCAGTGCTGCAGTGTGCGTGGCGTGGGCATCCTTCCAG
CTGACTCATGGTTTGAAAAACCGTTGTTTTATTTAAATATCCACAGTGGTAGGGCACACACTGAAGTTGGCTTTTCAGCCAGCACTGAAT
GTATCCATCAGGACATGCGTCTTCAGGTGCCTGATCTTTGTAGTCAGGCTGTGGGAACGGTCTCTGCAGAGCTTCATAACTGGGAATTTG
ATTTGAAGAAGTCCATGTCATATGTGTAACTAGTACTAATTATAAATATAAAATACACAATATAAAATATGAAACTCAATAATAAACAGT

>In-frame_ENST00000272454_ENST00000355654_TCGA-HC-7078_RGPD5_chr2_110552114_+_TMEM18_chr2_675630_length(amino acids)=178AA_start in transcript=93_stop in transcript=629
MLQWLAGTFLLEVATAAGLSGARTRLGSQVGGAMRRSKADVERYVASVLGLTPSPRQQTDWTEPWLMGLATFHALCVLLTCLSSRSYRLQ

--------------------------------------------------------------
>In-frame_ENST00000272454_ENST00000405941_TCGA-HC-7078_RGPD5_chr2_110552114_+_TMEM18_chr2_675630_length(transcript)=787nt_BP=264nt
ACACAGTGCTGAGGCAGAACGCAGGTTCGTCACAGTGGGCCTCCGTGGGCGGCGCCGCACGCTCGTCACAGTGGGCCTCCGCCGGCTACG
CCGCTGCTTCAGTGGCTTGCAGGCACTTTCCTCTTGGAAGTGGCGACTGCTGCGGGGCTGAGCGGTGCTCGCACGCGTCTCGGGAGCCAG
GTTGGCGGCGCGATGAGGCGCAGCAAGGCCGATGTGGAGCGGTACGTCGCCTCGGTGCTGGGTCTCACCCCGTCGCCTCGACAGCAGACG
GACTGGACTGAGCCCTGGCTCATGGGGCTGGCCACCTTCCACGCGCTCTGCGTGCTCCTCACCTGCTTGTCCTCCCGAAGCTACAGACTA
CAGATCGGGCACTTTCTGTGTCTAGTCATCTTAGTCTACTGTGCTGAATACATCAATGAGGCGGCTGCGATGAACTGGAGATTATTTTCG
AAATACCAGTATTTCGACTCCAGGGGGATGTTCATTTCTATAGTATTTTCAGCCCCACTGCTGGTGAATGCCATGATCATTGTGGTTATG
TGGGTATGGAAGACTTTGAATGTGATGACTGACCTGAAGAATGCACAAGAGAGAAGAAAGGAAAAGAAAAGGAGAAGGAAAGAAGACTGA
GGGGCAGCAGCTGCTTGGAGTTTGCGTCCTTCCCGTCCACCCAGTGCAGCTCCCAGTGCTGCAGTGTGCGTGGCGTGGGCATCCTTCCAG

>In-frame_ENST00000272454_ENST00000405941_TCGA-HC-7078_RGPD5_chr2_110552114_+_TMEM18_chr2_675630_length(amino acids)=178AA_start in transcript=93_stop in transcript=629
MLQWLAGTFLLEVATAAGLSGARTRLGSQVGGAMRRSKADVERYVASVLGLTPSPRQQTDWTEPWLMGLATFHALCVLLTCLSSRSYRLQ

--------------------------------------------------------------
>In-frame_ENST00000016946_ENST00000281017_TCGA-HC-7078_RGPD5_chr2_110552114_+_TMEM18_chr2_675630_length(transcript)=2841nt_BP=230nt
GTGGGCCTCCGTGGGCGGCGCCGCACGCTCGTCACAGTGGGCCTCCGCCGGCTACGCCGCTGCTTCAGTGGCTTGCAGGCACTTTCCTCT
TGGAAGTGGCGACTGCTGCGGGGCTGAGCGGTGCTCGCACGCGTCTCGGGAGCCAGGTTGGCGGCGCGATGAGGCGCAGCAAGGCCGATG
TGGAGCGGTACGTCGCCTCGGTGCTGGGTCTCACCCCGTCGCCTCGACAGCAGACGGACTGGACTGAGCCCTGGCTCATGGGGCTGGCCA
CCTTCCACGCGCTCTGCGTGCTCCTCACCTGCTTGTCCTCCCGAAGCTACAGACTACAGATCGGGCACTTTCTGTGTCTAGTCATCTTAG
TCTACTGTGCTGAATACATCAATGAGGCGGCTGCGATGAACTGGAGATTATTTTCGAAATACCAGTATTTCGACTCCAGGGGGATGTTCA
TTTCTATAGTATTTTCAGCCCCACTGCTGGTGAATGCCATGATCATTGTGGTTATGTGGGTATGGAAGACTTTGAATGTGATGACTGACC
TGAAGAATGCACAAGAGAGAAGAAAGGAAAAGAAAAGGAGAAGGAAAGAAGACTGAGGGGCAGCAGCTGCTTGGAGTTTGCGTCCTTCCC
GTCCACCCAGTGCAGCTCCCAGTGCTGCAGTGTGCGTGGCGTGGGCATCCTTCCAGCTGACTCATGGTTTGAAAAACCGTTGTTTTATTT
AAATATCCACAGTGGTAGGGCACACACTGAAGTTGGCTTTTCAGCCAGCACTGAATGTATCCATCAGGACATGCGTCTTCAGGTGCCTGA
TCTTTGTAGTCAGGCTGTGGGAACGGTCTCTGCAGAGCTTCATAACTGGGAATTTGATTTGAAGAAGTCCATGTCATATGTGTAACTAGT
ACTAATTATAAATATAAAATACACAATATAAAATATGAAACTCAATAATAAACAGTGCCACCTGTACATGGGCACCATGCCCTCCTCCTC
GTGCTGTGTTTTCTAGTGCATGCCACAGTTCGCAGTAGAGGGTGTTTTCACCTTCCAAGACATGGGGCAAAGTTTGGAGACACCTGGTTG
TCACTGGAGGGGGTGGTGCTCCTGGCTTCTCCTGTGGAGCCCGGGGTGATGCATAAAATCCTGTGTGCCTGGGTCAGCCGCATCACAGAC
AATGACTTGACATGAAATGTCAGCTGTGCTGGGGCAGAGAGACCTTGGAAGGAAGCTCTTGGAAAATACGTTGTATCTCAGTTTGATGAA
CCAATTCACAAGAGGCTAGGCCCTCTCTAGCAAAGTTATGGGCTGCTTTACTGAAAACAGAATGGAAGCCCTGAAGTCAACACTCCATGG
AGAAGCGTGTCTTTCCTAATGTCCTGGTGTTCTGTTGATTTAGGTGCTTGGGAACACAATGCTCCCAGTTCTGTTAGGACAGGCATACTG
TTACTTTGCAATATCCACTTTATAAAATAGCTCCTGCCCAGTGGCTCTTGGTTCCTGTCAAATGTGGACCTGTAGTTTAAGAATGACAGG
TGGTTAGAGACCCAGATATTTAAAAATAGGTGTTCAATAAGGGAATACTGATTGTGCATTGTATCTGGATAGCATGCCTAATTGTGCATT
TCTGAAAGTTACCAATTCAAAATGTAATTGGAACAGTTATCTTTGATTAGACAAGCCTGGGAAGAGAATGTTGAGGTGCAGAGCTCACCA
GCCAAGTTCATGCCCCTCTCGGGCCTTTGTGGCTGAGAAGTGGGACAGAAAGATGATTAAGGTAATGTGTCCTCCCTGTAGCATTGTCCA
GGGCCGTTGTGTAGATATTTGACTTCACTGACAGAAAAGAAACCAGGGAGTTTGTAGAGACTGTGCATTTTTAGTATAACATTTTCACCA
TCTGATATGGTTTGGCTTTGTGTCCCCACCCAAATTGCATCTCAAATTGTAATCCCCATGTGTCAAGGGAGGGACCTGATGGGAGGTGAT
GGGATCATGGGGGTGGTTTCCCCTATGTTGTTATCATAATAGAGAGGGAGTTCTCACAAGATCTGCTGGTTTTAAAGACAGCAGTTTCCC
CTGCTGTCACTGTCTCTCTCCTGCTGCCTTGTGAAGAAGGTGCTTGTTTCTCCCTCTGCCATGATTGTAAGTTTCCCGAGGCCTCCCCGG
CCATGTGGAACTGAGTCAATTAAACTTCTTGTTTATAAAGTAATCCAGGTCTCAGGTAGTATCTTTATAGCAGTGTGAGAACAGACTAAT
TAAACATCTATATGTTATTTGGACTTAATATGGGGCCGTGTGATTGAATCTCAGTTTGCCTGTGATAAAGTAGTGTAACAGTATTGCTAG
CTTTGCATGAATTTGATGCTGATGACATGTCAGTGTGAAACCATGACGTGTGGTCTTTGATTTTCATTCTGCATGTGTGTGTCTGTGTTT
TGGAACAGTTATATTTTGGTTTTGTAAAAACAACCTTCACTTTATTTTTAACTGTGTAGTAAGTTTATATTCAATGCCTTAAAGTGCATT
GTTAACAATTGTCTTGATATGTTGTCCTCATTTTAGGGAAAGTCATAGAAGCCAAAATGATCAGCAGTTGAGTAATTTACGAAAGCACAG
GTGCAATCCCACTTTAAAGCACTGGGGGTTGCACAGAGCACACTGGTTTCAGGCTCCATAAATGTGGATGACTCACTGGAGAGCTTCATC
TGTTTAAGTAGAACAAATGTTTTTACTCTACTGATAAAGTACAGGAAAGGAGGTTTGGGATCAAAATTATTTTTCACATTCCAAACCTGT

>In-frame_ENST00000016946_ENST00000281017_TCGA-HC-7078_RGPD5_chr2_110552114_+_TMEM18_chr2_675630_length(amino acids)=178AA_start in transcript=59_stop in transcript=595
MLQWLAGTFLLEVATAAGLSGARTRLGSQVGGAMRRSKADVERYVASVLGLTPSPRQQTDWTEPWLMGLATFHALCVLLTCLSSRSYRLQ

--------------------------------------------------------------
>In-frame_ENST00000016946_ENST00000355654_TCGA-HC-7078_RGPD5_chr2_110552114_+_TMEM18_chr2_675630_length(transcript)=987nt_BP=230nt
GTGGGCCTCCGTGGGCGGCGCCGCACGCTCGTCACAGTGGGCCTCCGCCGGCTACGCCGCTGCTTCAGTGGCTTGCAGGCACTTTCCTCT
TGGAAGTGGCGACTGCTGCGGGGCTGAGCGGTGCTCGCACGCGTCTCGGGAGCCAGGTTGGCGGCGCGATGAGGCGCAGCAAGGCCGATG
TGGAGCGGTACGTCGCCTCGGTGCTGGGTCTCACCCCGTCGCCTCGACAGCAGACGGACTGGACTGAGCCCTGGCTCATGGGGCTGGCCA
CCTTCCACGCGCTCTGCGTGCTCCTCACCTGCTTGTCCTCCCGAAGCTACAGACTACAGATCGGGCACTTTCTGTGTCTAGTCATCTTAG
TCTACTGTGCTGAATACATCAATGAGGCGGCTGCGATGAACTGGAGATTATTTTCGAAATACCAGTATTTCGACTCCAGGGGGATGTTCA
TTTCTATAGTATTTTCAGCCCCACTGCTGGTGAATGCCATGATCATTGTGGTTATGTGGGTATGGAAGACTTTGAATGTGATGACTGACC
TGAAGAATGCACAAGAGAGAAGAAAGGAAAAGAAAAGGAGAAGGAAAGAAGACTGAGGGGCAGCAGCTGCTTGGAGTTTGCGTCCTTCCC
GTCCACCCAGTGCAGCTCCCAGTGCTGCAGTGTGCGTGGCGTGGGCATCCTTCCAGCTGACTCATGGTTTGAAAAACCGTTGTTTTATTT
AAATATCCACAGTGGTAGGGCACACACTGAAGTTGGCTTTTCAGCCAGCACTGAATGTATCCATCAGGACATGCGTCTTCAGGTGCCTGA
TCTTTGTAGTCAGGCTGTGGGAACGGTCTCTGCAGAGCTTCATAACTGGGAATTTGATTTGAAGAAGTCCATGTCATATGTGTAACTAGT

>In-frame_ENST00000016946_ENST00000355654_TCGA-HC-7078_RGPD5_chr2_110552114_+_TMEM18_chr2_675630_length(amino acids)=178AA_start in transcript=59_stop in transcript=595
MLQWLAGTFLLEVATAAGLSGARTRLGSQVGGAMRRSKADVERYVASVLGLTPSPRQQTDWTEPWLMGLATFHALCVLLTCLSSRSYRLQ

--------------------------------------------------------------
>In-frame_ENST00000016946_ENST00000405941_TCGA-HC-7078_RGPD5_chr2_110552114_+_TMEM18_chr2_675630_length(transcript)=753nt_BP=230nt
GTGGGCCTCCGTGGGCGGCGCCGCACGCTCGTCACAGTGGGCCTCCGCCGGCTACGCCGCTGCTTCAGTGGCTTGCAGGCACTTTCCTCT
TGGAAGTGGCGACTGCTGCGGGGCTGAGCGGTGCTCGCACGCGTCTCGGGAGCCAGGTTGGCGGCGCGATGAGGCGCAGCAAGGCCGATG
TGGAGCGGTACGTCGCCTCGGTGCTGGGTCTCACCCCGTCGCCTCGACAGCAGACGGACTGGACTGAGCCCTGGCTCATGGGGCTGGCCA
CCTTCCACGCGCTCTGCGTGCTCCTCACCTGCTTGTCCTCCCGAAGCTACAGACTACAGATCGGGCACTTTCTGTGTCTAGTCATCTTAG
TCTACTGTGCTGAATACATCAATGAGGCGGCTGCGATGAACTGGAGATTATTTTCGAAATACCAGTATTTCGACTCCAGGGGGATGTTCA
TTTCTATAGTATTTTCAGCCCCACTGCTGGTGAATGCCATGATCATTGTGGTTATGTGGGTATGGAAGACTTTGAATGTGATGACTGACC
TGAAGAATGCACAAGAGAGAAGAAAGGAAAAGAAAAGGAGAAGGAAAGAAGACTGAGGGGCAGCAGCTGCTTGGAGTTTGCGTCCTTCCC
GTCCACCCAGTGCAGCTCCCAGTGCTGCAGTGTGCGTGGCGTGGGCATCCTTCCAGCTGACTCATGGTTTGAAAAACCGTTGTTTTATTT

>In-frame_ENST00000016946_ENST00000405941_TCGA-HC-7078_RGPD5_chr2_110552114_+_TMEM18_chr2_675630_length(amino acids)=178AA_start in transcript=59_stop in transcript=595
MLQWLAGTFLLEVATAAGLSGARTRLGSQVGGAMRRSKADVERYVASVLGLTPSPRQQTDWTEPWLMGLATFHALCVLLTCLSSRSYRLQ

--------------------------------------------------------------

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Fusion Gene PPI Analysis for RGPD5-TMEM18


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RGPD5-TMEM18


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for RGPD5-TMEM18


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneTMEM18C0011860Diabetes Mellitus, Non-Insulin-Dependent1CTD_human
TgeneTMEM18C0028754Obesity1CTD_human