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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:RNF19A-F10 (FusionGDB2 ID:74460)

Fusion Gene Summary for RNF19A-F10

check button Fusion gene summary
Fusion gene informationFusion gene name: RNF19A-F10
Fusion gene ID: 74460
HgeneTgene
Gene symbol

RNF19A

F10

Gene ID

25897

83541

Gene namering finger protein 19A, RBR E3 ubiquitin protein ligasefamily with sequence similarity 110 member A
SynonymsRNF19C20orf55|F10|bA371L19.3
Cytomap

8q22.2

20p13

Type of geneprotein-codingprotein-coding
DescriptionE3 ubiquitin-protein ligase RNF19Adouble ring-finger proteinprotein p38 interacting with transcription factor Sp1ring finger protein 19ring finger protein 19A, E3 ubiquitin protein ligasering-IBR-ring domain containing protein Dorfinprotein FAM110A
Modification date2020031320200313
UniProtAcc.

P00742

Ensembl transtripts involved in fusion geneENST00000341084, ENST00000519449, 
ENST00000523255, 		ENST00000409306, 
ENST00000375551, ENST00000375559, 
ENST00000483537, 
Fusion gene scores* DoF score20 X 21 X 10=42006 X 7 X 4=168
# samples 347
** MAII scorelog2(34/4200*10)=-3.62678267641578
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/168*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RNF19A [Title/Abstract] AND F10 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRNF19A(101299729)-F10(113792771), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across RNF19A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across F10 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ESCATCGA-VR-A8EX-01ARNF19Achr8

101299729

-F10chr13

113792771

+


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Fusion Gene ORF analysis for RNF19A-F10

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000341084ENST00000409306RNF19Achr8

101299729

-F10chr13

113792771

+
In-frameENST00000341084ENST00000375551RNF19Achr8

101299729

-F10chr13

113792771

+
In-frameENST00000341084ENST00000375559RNF19Achr8

101299729

-F10chr13

113792771

+
5CDS-intronENST00000341084ENST00000483537RNF19Achr8

101299729

-F10chr13

113792771

+
In-frameENST00000519449ENST00000409306RNF19Achr8

101299729

-F10chr13

113792771

+
In-frameENST00000519449ENST00000375551RNF19Achr8

101299729

-F10chr13

113792771

+
In-frameENST00000519449ENST00000375559RNF19Achr8

101299729

-F10chr13

113792771

+
5CDS-intronENST00000519449ENST00000483537RNF19Achr8

101299729

-F10chr13

113792771

+
intron-3CDSENST00000523255ENST00000409306RNF19Achr8

101299729

-F10chr13

113792771

+
intron-3CDSENST00000523255ENST00000375551RNF19Achr8

101299729

-F10chr13

113792771

+
intron-3CDSENST00000523255ENST00000375559RNF19Achr8

101299729

-F10chr13

113792771

+
intron-intronENST00000523255ENST00000483537RNF19Achr8

101299729

-F10chr13

113792771

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000341084RNF19Achr8101299729-ENST00000409306F10chr13113792771+240512285541336260
ENST00000341084RNF19Achr8101299729-ENST00000375551F10chr13113792771+246412285541336260
ENST00000341084RNF19Achr8101299729-ENST00000375559F10chr13113792771+2476122812222463413
ENST00000519449RNF19Achr8101299729-ENST00000409306F10chr13113792771+21689913171099260
ENST00000519449RNF19Achr8101299729-ENST00000375551F10chr13113792771+22279913171099260
ENST00000519449RNF19Achr8101299729-ENST00000375559F10chr13113792771+22399919852226413

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000341084ENST00000409306RNF19Achr8101299729-F10chr13113792771+0.0169960320.983004
ENST00000341084ENST00000375551RNF19Achr8101299729-F10chr13113792771+0.0172541810.98274577
ENST00000341084ENST00000375559RNF19Achr8101299729-F10chr13113792771+0.0172289740.982771
ENST00000519449ENST00000409306RNF19Achr8101299729-F10chr13113792771+0.0201225620.9798774
ENST00000519449ENST00000375551RNF19Achr8101299729-F10chr13113792771+0.0200949310.9799051
ENST00000519449ENST00000375559RNF19Achr8101299729-F10chr13113792771+0.0197330660.9802669

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Fusion Genomic Features for RNF19A-F10


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
RNF19Achr8101299728-F10chr13113792770+4.48E-050.9999552
RNF19Achr8101299728-F10chr13113792770+4.48E-050.9999552

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for RNF19A-F10


check button Go to

FGviewer for the breakpoints of chr8:101299729-chr13:113792771

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.F10

P00742

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRNF19Achr8:101299729chr13:113792771ENST00000341084-210132_179224.66666666666666839.0Zinc fingerRING-type 1
HgeneRNF19Achr8:101299729chr13:113792771ENST00000519449-311132_179224.66666666666666839.0Zinc fingerRING-type 1
TgeneF10chr8:101299729chr13:113792771ENST0000037555918125_16577.0489.0DomainEGF-like 2
TgeneF10chr8:101299729chr13:113792771ENST0000037555918235_46777.0489.0DomainPeptidase S1
TgeneF10chr8:101299729chr13:113792771ENST000003755591886_12277.0489.0DomainEGF-like 1%3B calcium-binding
TgeneF10chr8:101299729chr13:113792771ENST0000037555918183_20377.0489.0RegionNote=O-glycosylated at one site
TgeneF10chr8:101299729chr13:113792771ENST0000037555918476_48577.0489.0RegionNote=O-glycosylated at one site

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRNF19Achr8:101299729chr13:113792771ENST00000341084-210128_351224.66666666666666839.0RegionTRIAD supradomain
HgeneRNF19Achr8:101299729chr13:113792771ENST00000519449-311128_351224.66666666666666839.0RegionTRIAD supradomain
HgeneRNF19Achr8:101299729chr13:113792771ENST00000341084-210368_388224.66666666666666839.0TransmembraneHelical
HgeneRNF19Achr8:101299729chr13:113792771ENST00000341084-210424_444224.66666666666666839.0TransmembraneHelical
HgeneRNF19Achr8:101299729chr13:113792771ENST00000519449-311368_388224.66666666666666839.0TransmembraneHelical
HgeneRNF19Achr8:101299729chr13:113792771ENST00000519449-311424_444224.66666666666666839.0TransmembraneHelical
HgeneRNF19Achr8:101299729chr13:113792771ENST00000341084-210199_264224.66666666666666839.0Zinc fingerIBR-type
HgeneRNF19Achr8:101299729chr13:113792771ENST00000341084-210301_332224.66666666666666839.0Zinc fingerRING-type 2%3B atypical
HgeneRNF19Achr8:101299729chr13:113792771ENST00000519449-311199_264224.66666666666666839.0Zinc fingerIBR-type
HgeneRNF19Achr8:101299729chr13:113792771ENST00000519449-311301_332224.66666666666666839.0Zinc fingerRING-type 2%3B atypical
TgeneF10chr8:101299729chr13:113792771ENST000003755591841_8577.0489.0DomainGla


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Fusion Gene Sequence for RNF19A-F10


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000341084_ENST00000409306_TCGA-VR-A8EX-01A_RNF19A_chr8_101299729_-_F10_chr13_113792771_length(transcript)=2405nt_BP=1228nt
GGGGGCCGCAGTCGGGGCCACCCGGGTGCAGCGGGGCGGCTCCTGCGCGGGCGCGGAACGAACGTGCGCAAGGGAACAGCCGCGTCCAGA
GCCGCCCGCAGCGGGCCCGGTGGGCGTGACGCCATGACGCACAGCACGCGGGCGGCGCGCTGGGGCGGGGCGGCCGGGGGCGGGAGGAAG
AAGTGGGAGGAGGAGGAGGGGAAAGCGGGGGCTGCGGGAGGGGGAGGTGGTAGTTGCGGCGCTGGTTCCCGGGAGCAGCCGTCGAGCCAC
AACTGCGGAGGAGGAGTTCGGGAAAGCGGCCGTCGGGACTCCTCCCCTCCGTCGTCTCCGCCCCGGTTGAGAGGCGCCTCGGCGCATCGG
AGGGACCCTCCCCCGCGCTTCCTCAGGCTGCTGTCGCCGCTGCTGGGAGATGGGCCTACTCGCCCGCCACCCTGCGCTGCCGCCGCTCTG
AGGAGTTAAAGAACATCCATGATAGCAGTCTTCTGTAAATCGAACTTTTCAAGAATTCTCTGAAGGAACCAAGTAGGATATTCTTACATC
ATGACTTAATGTGAATGCAAGAACAAGAAATAGGTTTTATCTCTAAATATAATGAAGGGCTGTGTGTAAACACTGACCCTGTCTCAATTC
TAACAAGCATTTTAGACATGAGTTTACATCGGCAAATGGGTTCAGATCGAGATCTTCAGTCCTCTGCTTCATCTGTGAGCTTGCCTTCAG
TCAAAAAGGCACCCAAAAAAAGAAGAATTTCAATAGGCTCCCTGTTTCGGAGGAAAAAAGATAACAAACGTAAATCAAGGGAGCTAAATG
GCGGGGTGGATGGAATTGCAAGTATTGAAAGTATACATTCTGAAATGTGTACTGATAAGAACTCCATTTTCTCTACAAATACCTCTTCTG
ACAATGGATTAACTTCCATCAGCAAACAAATTGGAGACTTCATAGAGTGCCCTTTGTGCCTTTTGCGGCATTCTAAAGACAGATTTCCTG
ATATAATGACTTGTCATCACAGATCTTGTGTGGATTGCTTACGACAATATTTAAGGATAGAAATCTCTGAAAGCAGAGTTAATATTAGTT
GCCCAGAATGTACTGAACGGTTTAATCCCCATGATATTCGCTTGATATTAAGTGATGATGTCTTGATGGAAAAATACGAAGAATTTATGC
TTAGACGGTGGCTTGTTGCAGATCCTGATTGTAGGTGGTGTCCAGCTCCAGACTGTGGAATGAATTCTGGAATAAATACAAAGATGGCGA
CCAGTGTGAGACCAGTCCTTGCCAGAACCAGGGCAAATGTAAAGACGGCCTCGGGGAATACACCTGCACCTGTTTAGAAGGATTCGAAGG
CAAAAACTGTGAATTATTCACACGGAAGCTCTGCAGCCTGGACAACGGGGACTGTGACCAGTTCTGCCACGAGGAACAGAACTCTGTGGT
GTGCTCCTGCGCCCGCGGGTACACCCTGGCTGACAACGGCAAGGCCTGCATTCCCACAGGGCCCTACCCCTGTGGGAAACAGACCCTGGA
ACGCAGGAAGAGGTCAGTGGCCCAGGCCACCAGCAGCAGCGGGGAGGCCCCTGACAGCATCACATGGAAGCCATATGATGCAGCCGACCT
GGACCCCACCGAGAACCCCTTCGACCTGCTTGACTTCAACCAGACGCAGCCTGAGAGGGGCGACAACAACCTCACCAGGATCGTGGGAGG
CCAGGAATGCAAGGACGGGGAGTGTCCCTGGCAGGCCCTGCTCATCAATGAGGAAAACGAGGGTTTCTGTGGTGGAACCATTCTGAGCGA
GTTCTACATCCTAACGGCAGCCCACTGTCTCTACCAAGCCAAGAGATTCAAGGTGAGGGGGACCGGAACACGGAGCAGGAGGAGGGCGGT
GAGGCGGTGCACGAGGTGGAGGTGGTCATCAAGCACAACCGGTTCACAAAGGAGACCTATGACTTCGACATCGCCGTGCTCCGGCTCAAG
ACCCCCATCACCTTCCGCATGAACGTGGCGCCTGCCTGCCTCCCCGAGCGTGACTGGGCCGAGTCCACGCTGATGACGCAGAAGACGGGG
ATTGTGAGCGGCTTCGGGCGCACCCACGAGAAGGGCCGGCAGTCCACCAGGCTCAAGATGCTGGAGGTGCCCTACGTGGACCGCAACAGC
TGCAAGCTGTCCAGCAGCTTCATCATCACCCAGAACATGTTCTGTGCCGGCTACGACACCAAGCAGGAGGATGCCTGCCAGGGGGACAGC
GGGGGCCCGCACGTCACCCGCTTCAAGGACACCTACTTCGTGACAGGCATCGTCAGCTGGGGAGAGGGCTGTGCCCGTAAGGGGAAGTAC

>In-frame_ENST00000341084_ENST00000409306_TCGA-VR-A8EX-01A_RNF19A_chr8_101299729_-_F10_chr13_113792771_length(amino acids)=260AA_start in transcript=554_stop in transcript=1336
MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAPKKRRISIGSLFRRKKDNKRKSRELNGGVDG
IASIESIHSEMCTDKNSIFSTNTSSDNGLTSISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT

--------------------------------------------------------------
>In-frame_ENST00000341084_ENST00000375551_TCGA-VR-A8EX-01A_RNF19A_chr8_101299729_-_F10_chr13_113792771_length(transcript)=2464nt_BP=1228nt
GGGGGCCGCAGTCGGGGCCACCCGGGTGCAGCGGGGCGGCTCCTGCGCGGGCGCGGAACGAACGTGCGCAAGGGAACAGCCGCGTCCAGA
GCCGCCCGCAGCGGGCCCGGTGGGCGTGACGCCATGACGCACAGCACGCGGGCGGCGCGCTGGGGCGGGGCGGCCGGGGGCGGGAGGAAG
AAGTGGGAGGAGGAGGAGGGGAAAGCGGGGGCTGCGGGAGGGGGAGGTGGTAGTTGCGGCGCTGGTTCCCGGGAGCAGCCGTCGAGCCAC
AACTGCGGAGGAGGAGTTCGGGAAAGCGGCCGTCGGGACTCCTCCCCTCCGTCGTCTCCGCCCCGGTTGAGAGGCGCCTCGGCGCATCGG
AGGGACCCTCCCCCGCGCTTCCTCAGGCTGCTGTCGCCGCTGCTGGGAGATGGGCCTACTCGCCCGCCACCCTGCGCTGCCGCCGCTCTG
AGGAGTTAAAGAACATCCATGATAGCAGTCTTCTGTAAATCGAACTTTTCAAGAATTCTCTGAAGGAACCAAGTAGGATATTCTTACATC
ATGACTTAATGTGAATGCAAGAACAAGAAATAGGTTTTATCTCTAAATATAATGAAGGGCTGTGTGTAAACACTGACCCTGTCTCAATTC
TAACAAGCATTTTAGACATGAGTTTACATCGGCAAATGGGTTCAGATCGAGATCTTCAGTCCTCTGCTTCATCTGTGAGCTTGCCTTCAG
TCAAAAAGGCACCCAAAAAAAGAAGAATTTCAATAGGCTCCCTGTTTCGGAGGAAAAAAGATAACAAACGTAAATCAAGGGAGCTAAATG
GCGGGGTGGATGGAATTGCAAGTATTGAAAGTATACATTCTGAAATGTGTACTGATAAGAACTCCATTTTCTCTACAAATACCTCTTCTG
ACAATGGATTAACTTCCATCAGCAAACAAATTGGAGACTTCATAGAGTGCCCTTTGTGCCTTTTGCGGCATTCTAAAGACAGATTTCCTG
ATATAATGACTTGTCATCACAGATCTTGTGTGGATTGCTTACGACAATATTTAAGGATAGAAATCTCTGAAAGCAGAGTTAATATTAGTT
GCCCAGAATGTACTGAACGGTTTAATCCCCATGATATTCGCTTGATATTAAGTGATGATGTCTTGATGGAAAAATACGAAGAATTTATGC
TTAGACGGTGGCTTGTTGCAGATCCTGATTGTAGGTGGTGTCCAGCTCCAGACTGTGGAATGAATTCTGGAATAAATACAAAGATGGCGA
CCAGTGTGAGACCAGTCCTTGCCAGAACCAGGGCAAATGTAAAGACGGCCTCGGGGAATACACCTGCACCTGTTTAGAAGGATTCGAAGG
CAAAAACTGTGAATTATTCACACGGAAGCTCTGCAGCCTGGACAACGGGGACTGTGACCAGTTCTGCCACGAGGAACAGAACTCTGTGGT
GTGCTCCTGCGCCCGCGGGTACACCCTGGCTGACAACGGCAAGGCCTGCATTCCCACAGGGCCCTACCCCTGTGGGAAACAGACCCTGGA
ACGCAGGAAGAGGTCAGTGGCCCAGGCCACCAGCAGCAGCGGGGAGGCCCCTGACAGCATCACATGGAAGCCATATGATGCAGCCGACCT
GGACCCCACCGAGAACCCCTTCGACCTGCTTGACTTCAACCAGACGCAGCCTGAGAGGGGCGACAACAACCTCACCAGGATCGTGGGAGG
CCAGGAATGCAAGGACGGGGAGTGTCCCTGGCAGGCCCTGCTCATCAATGAGGAAAACGAGGGTTTCTGTGGTGGAACCATTCTGAGCGA
GTTCTACATCCTAACGGCAGCCCACTGTCTCTACCAAGCCAAGAGATTCAAGGGGACCGGAACACGGAGCAGGAGGAGGGCGGTGAGGCG
GTGCACGAGGTGGAGGTGGTCATCAAGCACAACCGGTTCACAAAGGAGACCTATGACTTCGACATCGCCGTGCTCCGGCTCAAGACCCCC
ATCACCTTCCGCATGAACGTGGCGCCTGCCTGCCTCCCCGAGCGTGACTGGGCCGAGTCCACGCTGATGACGCAGAAGACGGGGATTGTG
AGCGGCTTCGGGCGCACCCACGAGAAGGGCCGGCAGTCCACCAGGCTCAAGATGCTGGAGGTGCCCTACGTGGACCGCAACAGCTGCAAG
CTGTCCAGCAGCTTCATCATCACCCAGAACATGTTCTGTGCCGGCTACGACACCAAGCAGGAGGATGCCTGCCAGGGGGACAGCGGGGGC
CCGCACGTCACCCGCTTCAAGGACACCTACTTCGTGACAGGCATCGTCAGCTGGGGAGAGGGCTGTGCCCGTAAGGGGAAGTACGGGATC
TACACCAAGGTCACCGCCTTCCTCAAGTGGATCGACAGGTCCATGAAAACCAGGGGCTTGCCCAAGGCCAAGAGCCATGCCCCGGAGGTC

>In-frame_ENST00000341084_ENST00000375551_TCGA-VR-A8EX-01A_RNF19A_chr8_101299729_-_F10_chr13_113792771_length(amino acids)=260AA_start in transcript=554_stop in transcript=1336
MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAPKKRRISIGSLFRRKKDNKRKSRELNGGVDG
IASIESIHSEMCTDKNSIFSTNTSSDNGLTSISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT

--------------------------------------------------------------
>In-frame_ENST00000341084_ENST00000375559_TCGA-VR-A8EX-01A_RNF19A_chr8_101299729_-_F10_chr13_113792771_length(transcript)=2476nt_BP=1228nt
GGGGGCCGCAGTCGGGGCCACCCGGGTGCAGCGGGGCGGCTCCTGCGCGGGCGCGGAACGAACGTGCGCAAGGGAACAGCCGCGTCCAGA
GCCGCCCGCAGCGGGCCCGGTGGGCGTGACGCCATGACGCACAGCACGCGGGCGGCGCGCTGGGGCGGGGCGGCCGGGGGCGGGAGGAAG
AAGTGGGAGGAGGAGGAGGGGAAAGCGGGGGCTGCGGGAGGGGGAGGTGGTAGTTGCGGCGCTGGTTCCCGGGAGCAGCCGTCGAGCCAC
AACTGCGGAGGAGGAGTTCGGGAAAGCGGCCGTCGGGACTCCTCCCCTCCGTCGTCTCCGCCCCGGTTGAGAGGCGCCTCGGCGCATCGG
AGGGACCCTCCCCCGCGCTTCCTCAGGCTGCTGTCGCCGCTGCTGGGAGATGGGCCTACTCGCCCGCCACCCTGCGCTGCCGCCGCTCTG
AGGAGTTAAAGAACATCCATGATAGCAGTCTTCTGTAAATCGAACTTTTCAAGAATTCTCTGAAGGAACCAAGTAGGATATTCTTACATC
ATGACTTAATGTGAATGCAAGAACAAGAAATAGGTTTTATCTCTAAATATAATGAAGGGCTGTGTGTAAACACTGACCCTGTCTCAATTC
TAACAAGCATTTTAGACATGAGTTTACATCGGCAAATGGGTTCAGATCGAGATCTTCAGTCCTCTGCTTCATCTGTGAGCTTGCCTTCAG
TCAAAAAGGCACCCAAAAAAAGAAGAATTTCAATAGGCTCCCTGTTTCGGAGGAAAAAAGATAACAAACGTAAATCAAGGGAGCTAAATG
GCGGGGTGGATGGAATTGCAAGTATTGAAAGTATACATTCTGAAATGTGTACTGATAAGAACTCCATTTTCTCTACAAATACCTCTTCTG
ACAATGGATTAACTTCCATCAGCAAACAAATTGGAGACTTCATAGAGTGCCCTTTGTGCCTTTTGCGGCATTCTAAAGACAGATTTCCTG
ATATAATGACTTGTCATCACAGATCTTGTGTGGATTGCTTACGACAATATTTAAGGATAGAAATCTCTGAAAGCAGAGTTAATATTAGTT
GCCCAGAATGTACTGAACGGTTTAATCCCCATGATATTCGCTTGATATTAAGTGATGATGTCTTGATGGAAAAATACGAAGAATTTATGC
TTAGACGGTGGCTTGTTGCAGATCCTGATTGTAGGTGGTGTCCAGCTCCAGACTGTGGAATGAATTCTGGAATAAATACAAAGATGGCGA
CCAGTGTGAGACCAGTCCTTGCCAGAACCAGGGCAAATGTAAAGACGGCCTCGGGGAATACACCTGCACCTGTTTAGAAGGATTCGAAGG
CAAAAACTGTGAATTATTCACACGGAAGCTCTGCAGCCTGGACAACGGGGACTGTGACCAGTTCTGCCACGAGGAACAGAACTCTGTGGT
GTGCTCCTGCGCCCGCGGGTACACCCTGGCTGACAACGGCAAGGCCTGCATTCCCACAGGGCCCTACCCCTGTGGGAAACAGACCCTGGA
ACGCAGGAAGAGGTCAGTGGCCCAGGCCACCAGCAGCAGCGGGGAGGCCCCTGACAGCATCACATGGAAGCCATATGATGCAGCCGACCT
GGACCCCACCGAGAACCCCTTCGACCTGCTTGACTTCAACCAGACGCAGCCTGAGAGGGGCGACAACAACCTCACCAGGATCGTGGGAGG
CCAGGAATGCAAGGACGGGGAGTGTCCCTGGCAGGCCCTGCTCATCAATGAGGAAAACGAGGGTTTCTGTGGTGGAACCATTCTGAGCGA
GTTCTACATCCTAACGGCAGCCCACTGTCTCTACCAAGCCAAGAGATTCAAGGTGAGGGTAGGGGACCGGAACACGGAGCAGGAGGAGGG
CGGTGAGGCGGTGCACGAGGTGGAGGTGGTCATCAAGCACAACCGGTTCACAAAGGAGACCTATGACTTCGACATCGCCGTGCTCCGGCT
CAAGACCCCCATCACCTTCCGCATGAACGTGGCGCCTGCCTGCCTCCCCGAGCGTGACTGGGCCGAGTCCACGCTGATGACGCAGAAGAC
GGGGATTGTGAGCGGCTTCGGGCGCACCCACGAGAAGGGCCGGCAGTCCACCAGGCTCAAGATGCTGGAGGTGCCCTACGTGGACCGCAA
CAGCTGCAAGCTGTCCAGCAGCTTCATCATCACCCAGAACATGTTCTGTGCCGGCTACGACACCAAGCAGGAGGATGCCTGCCAGGGGGA
CAGCGGGGGCCCGCACGTCACCCGCTTCAAGGACACCTACTTCGTGACAGGCATCGTCAGCTGGGGAGAGGGCTGTGCCCGTAAGGGGAA
GTACGGGATCTACACCAAGGTCACCGCCTTCCTCAAGTGGATCGACAGGTCCATGAAAACCAGGGGCTTGCCCAAGGCCAAGAGCCATGC

>In-frame_ENST00000341084_ENST00000375559_TCGA-VR-A8EX-01A_RNF19A_chr8_101299729_-_F10_chr13_113792771_length(amino acids)=413AA_start in transcript=1222_stop in transcript=2463
MWNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACI
PTGPYPCGKQTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINE
ENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPE
RDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTG

--------------------------------------------------------------
>In-frame_ENST00000519449_ENST00000409306_TCGA-VR-A8EX-01A_RNF19A_chr8_101299729_-_F10_chr13_113792771_length(transcript)=2168nt_BP=991nt
ATAGTCACCAGAAGCTGGAAGAGTCAAAGGACACATTCTCCCCTCAAGCCCCAGTGGGAGCACGGCCCAGCTGGATTTTGGACTTCTGGC
CTCCAGAACTAGACAGGGCCTCACTGTGTCACCCAGGGTGGAATACAGTGGTGTGATCATAGCTCACTGCAGCCTGGAATTCCTGGGCTC
AAGCAACCCTGCCACCTCAGCCTTCCAAGTAGCTAGGACTACAGAACATCCATGATAGCAGTCTTCTGTAAATCGAACTTTTCAAGAATT
CTCTGAAGGAACCAAGTAGGATATTCTTACATCATGACTTAATGTGAATGCAAGAACAAGAAATAGGTTTTATCTCTAAATATAATGAAG
GGCTGTGTGTAAACACTGACCCTGTCTCAATTCTAACAAGCATTTTAGACATGAGTTTACATCGGCAAATGGGTTCAGATCGAGATCTTC
AGTCCTCTGCTTCATCTGTGAGCTTGCCTTCAGTCAAAAAGGCACCCAAAAAAAGAAGAATTTCAATAGGCTCCCTGTTTCGGAGGAAAA
AAGATAACAAACGTAAATCAAGGGAGCTAAATGGCGGGGTGGATGGAATTGCAAGTATTGAAAGTATACATTCTGAAATGTGTACTGATA
AGAACTCCATTTTCTCTACAAATACCTCTTCTGACAATGGATTAACTTCCATCAGCAAACAAATTGGAGACTTCATAGAGTGCCCTTTGT
GCCTTTTGCGGCATTCTAAAGACAGATTTCCTGATATAATGACTTGTCATCACAGATCTTGTGTGGATTGCTTACGACAATATTTAAGGA
TAGAAATCTCTGAAAGCAGAGTTAATATTAGTTGCCCAGAATGTACTGAACGGTTTAATCCCCATGATATTCGCTTGATATTAAGTGATG
ATGTCTTGATGGAAAAATACGAAGAATTTATGCTTAGACGGTGGCTTGTTGCAGATCCTGATTGTAGGTGGTGTCCAGCTCCAGACTGTG
GAATGAATTCTGGAATAAATACAAAGATGGCGACCAGTGTGAGACCAGTCCTTGCCAGAACCAGGGCAAATGTAAAGACGGCCTCGGGGA
ATACACCTGCACCTGTTTAGAAGGATTCGAAGGCAAAAACTGTGAATTATTCACACGGAAGCTCTGCAGCCTGGACAACGGGGACTGTGA
CCAGTTCTGCCACGAGGAACAGAACTCTGTGGTGTGCTCCTGCGCCCGCGGGTACACCCTGGCTGACAACGGCAAGGCCTGCATTCCCAC
AGGGCCCTACCCCTGTGGGAAACAGACCCTGGAACGCAGGAAGAGGTCAGTGGCCCAGGCCACCAGCAGCAGCGGGGAGGCCCCTGACAG
CATCACATGGAAGCCATATGATGCAGCCGACCTGGACCCCACCGAGAACCCCTTCGACCTGCTTGACTTCAACCAGACGCAGCCTGAGAG
GGGCGACAACAACCTCACCAGGATCGTGGGAGGCCAGGAATGCAAGGACGGGGAGTGTCCCTGGCAGGCCCTGCTCATCAATGAGGAAAA
CGAGGGTTTCTGTGGTGGAACCATTCTGAGCGAGTTCTACATCCTAACGGCAGCCCACTGTCTCTACCAAGCCAAGAGATTCAAGGTGAG
GGGGACCGGAACACGGAGCAGGAGGAGGGCGGTGAGGCGGTGCACGAGGTGGAGGTGGTCATCAAGCACAACCGGTTCACAAAGGAGACC
TATGACTTCGACATCGCCGTGCTCCGGCTCAAGACCCCCATCACCTTCCGCATGAACGTGGCGCCTGCCTGCCTCCCCGAGCGTGACTGG
GCCGAGTCCACGCTGATGACGCAGAAGACGGGGATTGTGAGCGGCTTCGGGCGCACCCACGAGAAGGGCCGGCAGTCCACCAGGCTCAAG
ATGCTGGAGGTGCCCTACGTGGACCGCAACAGCTGCAAGCTGTCCAGCAGCTTCATCATCACCCAGAACATGTTCTGTGCCGGCTACGAC
ACCAAGCAGGAGGATGCCTGCCAGGGGGACAGCGGGGGCCCGCACGTCACCCGCTTCAAGGACACCTACTTCGTGACAGGCATCGTCAGC
TGGGGAGAGGGCTGTGCCCGTAAGGGGAAGTACGGGATCTACACCAAGGTCACCGCCTTCCTCAAGTGGATCGACAGGTCCATGAAAACC

>In-frame_ENST00000519449_ENST00000409306_TCGA-VR-A8EX-01A_RNF19A_chr8_101299729_-_F10_chr13_113792771_length(amino acids)=260AA_start in transcript=317_stop in transcript=1099
MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAPKKRRISIGSLFRRKKDNKRKSRELNGGVDG
IASIESIHSEMCTDKNSIFSTNTSSDNGLTSISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT

--------------------------------------------------------------
>In-frame_ENST00000519449_ENST00000375551_TCGA-VR-A8EX-01A_RNF19A_chr8_101299729_-_F10_chr13_113792771_length(transcript)=2227nt_BP=991nt
ATAGTCACCAGAAGCTGGAAGAGTCAAAGGACACATTCTCCCCTCAAGCCCCAGTGGGAGCACGGCCCAGCTGGATTTTGGACTTCTGGC
CTCCAGAACTAGACAGGGCCTCACTGTGTCACCCAGGGTGGAATACAGTGGTGTGATCATAGCTCACTGCAGCCTGGAATTCCTGGGCTC
AAGCAACCCTGCCACCTCAGCCTTCCAAGTAGCTAGGACTACAGAACATCCATGATAGCAGTCTTCTGTAAATCGAACTTTTCAAGAATT
CTCTGAAGGAACCAAGTAGGATATTCTTACATCATGACTTAATGTGAATGCAAGAACAAGAAATAGGTTTTATCTCTAAATATAATGAAG
GGCTGTGTGTAAACACTGACCCTGTCTCAATTCTAACAAGCATTTTAGACATGAGTTTACATCGGCAAATGGGTTCAGATCGAGATCTTC
AGTCCTCTGCTTCATCTGTGAGCTTGCCTTCAGTCAAAAAGGCACCCAAAAAAAGAAGAATTTCAATAGGCTCCCTGTTTCGGAGGAAAA
AAGATAACAAACGTAAATCAAGGGAGCTAAATGGCGGGGTGGATGGAATTGCAAGTATTGAAAGTATACATTCTGAAATGTGTACTGATA
AGAACTCCATTTTCTCTACAAATACCTCTTCTGACAATGGATTAACTTCCATCAGCAAACAAATTGGAGACTTCATAGAGTGCCCTTTGT
GCCTTTTGCGGCATTCTAAAGACAGATTTCCTGATATAATGACTTGTCATCACAGATCTTGTGTGGATTGCTTACGACAATATTTAAGGA
TAGAAATCTCTGAAAGCAGAGTTAATATTAGTTGCCCAGAATGTACTGAACGGTTTAATCCCCATGATATTCGCTTGATATTAAGTGATG
ATGTCTTGATGGAAAAATACGAAGAATTTATGCTTAGACGGTGGCTTGTTGCAGATCCTGATTGTAGGTGGTGTCCAGCTCCAGACTGTG
GAATGAATTCTGGAATAAATACAAAGATGGCGACCAGTGTGAGACCAGTCCTTGCCAGAACCAGGGCAAATGTAAAGACGGCCTCGGGGA
ATACACCTGCACCTGTTTAGAAGGATTCGAAGGCAAAAACTGTGAATTATTCACACGGAAGCTCTGCAGCCTGGACAACGGGGACTGTGA
CCAGTTCTGCCACGAGGAACAGAACTCTGTGGTGTGCTCCTGCGCCCGCGGGTACACCCTGGCTGACAACGGCAAGGCCTGCATTCCCAC
AGGGCCCTACCCCTGTGGGAAACAGACCCTGGAACGCAGGAAGAGGTCAGTGGCCCAGGCCACCAGCAGCAGCGGGGAGGCCCCTGACAG
CATCACATGGAAGCCATATGATGCAGCCGACCTGGACCCCACCGAGAACCCCTTCGACCTGCTTGACTTCAACCAGACGCAGCCTGAGAG
GGGCGACAACAACCTCACCAGGATCGTGGGAGGCCAGGAATGCAAGGACGGGGAGTGTCCCTGGCAGGCCCTGCTCATCAATGAGGAAAA
CGAGGGTTTCTGTGGTGGAACCATTCTGAGCGAGTTCTACATCCTAACGGCAGCCCACTGTCTCTACCAAGCCAAGAGATTCAAGGGGAC
CGGAACACGGAGCAGGAGGAGGGCGGTGAGGCGGTGCACGAGGTGGAGGTGGTCATCAAGCACAACCGGTTCACAAAGGAGACCTATGAC
TTCGACATCGCCGTGCTCCGGCTCAAGACCCCCATCACCTTCCGCATGAACGTGGCGCCTGCCTGCCTCCCCGAGCGTGACTGGGCCGAG
TCCACGCTGATGACGCAGAAGACGGGGATTGTGAGCGGCTTCGGGCGCACCCACGAGAAGGGCCGGCAGTCCACCAGGCTCAAGATGCTG
GAGGTGCCCTACGTGGACCGCAACAGCTGCAAGCTGTCCAGCAGCTTCATCATCACCCAGAACATGTTCTGTGCCGGCTACGACACCAAG
CAGGAGGATGCCTGCCAGGGGGACAGCGGGGGCCCGCACGTCACCCGCTTCAAGGACACCTACTTCGTGACAGGCATCGTCAGCTGGGGA
GAGGGCTGTGCCCGTAAGGGGAAGTACGGGATCTACACCAAGGTCACCGCCTTCCTCAAGTGGATCGACAGGTCCATGAAAACCAGGGGC

>In-frame_ENST00000519449_ENST00000375551_TCGA-VR-A8EX-01A_RNF19A_chr8_101299729_-_F10_chr13_113792771_length(amino acids)=260AA_start in transcript=317_stop in transcript=1099
MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAPKKRRISIGSLFRRKKDNKRKSRELNGGVDG
IASIESIHSEMCTDKNSIFSTNTSSDNGLTSISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT

--------------------------------------------------------------
>In-frame_ENST00000519449_ENST00000375559_TCGA-VR-A8EX-01A_RNF19A_chr8_101299729_-_F10_chr13_113792771_length(transcript)=2239nt_BP=991nt
ATAGTCACCAGAAGCTGGAAGAGTCAAAGGACACATTCTCCCCTCAAGCCCCAGTGGGAGCACGGCCCAGCTGGATTTTGGACTTCTGGC
CTCCAGAACTAGACAGGGCCTCACTGTGTCACCCAGGGTGGAATACAGTGGTGTGATCATAGCTCACTGCAGCCTGGAATTCCTGGGCTC
AAGCAACCCTGCCACCTCAGCCTTCCAAGTAGCTAGGACTACAGAACATCCATGATAGCAGTCTTCTGTAAATCGAACTTTTCAAGAATT
CTCTGAAGGAACCAAGTAGGATATTCTTACATCATGACTTAATGTGAATGCAAGAACAAGAAATAGGTTTTATCTCTAAATATAATGAAG
GGCTGTGTGTAAACACTGACCCTGTCTCAATTCTAACAAGCATTTTAGACATGAGTTTACATCGGCAAATGGGTTCAGATCGAGATCTTC
AGTCCTCTGCTTCATCTGTGAGCTTGCCTTCAGTCAAAAAGGCACCCAAAAAAAGAAGAATTTCAATAGGCTCCCTGTTTCGGAGGAAAA
AAGATAACAAACGTAAATCAAGGGAGCTAAATGGCGGGGTGGATGGAATTGCAAGTATTGAAAGTATACATTCTGAAATGTGTACTGATA
AGAACTCCATTTTCTCTACAAATACCTCTTCTGACAATGGATTAACTTCCATCAGCAAACAAATTGGAGACTTCATAGAGTGCCCTTTGT
GCCTTTTGCGGCATTCTAAAGACAGATTTCCTGATATAATGACTTGTCATCACAGATCTTGTGTGGATTGCTTACGACAATATTTAAGGA
TAGAAATCTCTGAAAGCAGAGTTAATATTAGTTGCCCAGAATGTACTGAACGGTTTAATCCCCATGATATTCGCTTGATATTAAGTGATG
ATGTCTTGATGGAAAAATACGAAGAATTTATGCTTAGACGGTGGCTTGTTGCAGATCCTGATTGTAGGTGGTGTCCAGCTCCAGACTGTG
GAATGAATTCTGGAATAAATACAAAGATGGCGACCAGTGTGAGACCAGTCCTTGCCAGAACCAGGGCAAATGTAAAGACGGCCTCGGGGA
ATACACCTGCACCTGTTTAGAAGGATTCGAAGGCAAAAACTGTGAATTATTCACACGGAAGCTCTGCAGCCTGGACAACGGGGACTGTGA
CCAGTTCTGCCACGAGGAACAGAACTCTGTGGTGTGCTCCTGCGCCCGCGGGTACACCCTGGCTGACAACGGCAAGGCCTGCATTCCCAC
AGGGCCCTACCCCTGTGGGAAACAGACCCTGGAACGCAGGAAGAGGTCAGTGGCCCAGGCCACCAGCAGCAGCGGGGAGGCCCCTGACAG
CATCACATGGAAGCCATATGATGCAGCCGACCTGGACCCCACCGAGAACCCCTTCGACCTGCTTGACTTCAACCAGACGCAGCCTGAGAG
GGGCGACAACAACCTCACCAGGATCGTGGGAGGCCAGGAATGCAAGGACGGGGAGTGTCCCTGGCAGGCCCTGCTCATCAATGAGGAAAA
CGAGGGTTTCTGTGGTGGAACCATTCTGAGCGAGTTCTACATCCTAACGGCAGCCCACTGTCTCTACCAAGCCAAGAGATTCAAGGTGAG
GGTAGGGGACCGGAACACGGAGCAGGAGGAGGGCGGTGAGGCGGTGCACGAGGTGGAGGTGGTCATCAAGCACAACCGGTTCACAAAGGA
GACCTATGACTTCGACATCGCCGTGCTCCGGCTCAAGACCCCCATCACCTTCCGCATGAACGTGGCGCCTGCCTGCCTCCCCGAGCGTGA
CTGGGCCGAGTCCACGCTGATGACGCAGAAGACGGGGATTGTGAGCGGCTTCGGGCGCACCCACGAGAAGGGCCGGCAGTCCACCAGGCT
CAAGATGCTGGAGGTGCCCTACGTGGACCGCAACAGCTGCAAGCTGTCCAGCAGCTTCATCATCACCCAGAACATGTTCTGTGCCGGCTA
CGACACCAAGCAGGAGGATGCCTGCCAGGGGGACAGCGGGGGCCCGCACGTCACCCGCTTCAAGGACACCTACTTCGTGACAGGCATCGT
CAGCTGGGGAGAGGGCTGTGCCCGTAAGGGGAAGTACGGGATCTACACCAAGGTCACCGCCTTCCTCAAGTGGATCGACAGGTCCATGAA

>In-frame_ENST00000519449_ENST00000375559_TCGA-VR-A8EX-01A_RNF19A_chr8_101299729_-_F10_chr13_113792771_length(amino acids)=413AA_start in transcript=985_stop in transcript=2226
MWNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACI
PTGPYPCGKQTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINE
ENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPE
RDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for RNF19A-F10


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneRNF19Achr8:101299729chr13:113792771ENST00000341084-210660_838224.66666666666666839.0CASR
HgeneRNF19Achr8:101299729chr13:113792771ENST00000519449-311660_838224.66666666666666839.0CASR


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RNF19A-F10


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
TgeneF10P00742DB00036Coagulation factor VIIa Recombinant HumanBiotechApproved
TgeneF10P00742DB01225EnoxaparinInhibitorSmall moleculeApproved
TgeneF10P00742DB06228RivaroxabanAntagonistSmall moleculeApproved
TgeneF10P00742DB06605ApixabanInhibitorSmall moleculeApproved
TgeneF10P00742DB09075EdoxabanInhibitorSmall moleculeApproved
TgeneF10P00742DB09141Protamine sulfateBiotechApproved
TgeneF10P00742DB09332KappadioneAgonistSmall moleculeApproved
TgeneF10P00742DB13149Protein S humanAntagonistBiotechApproved
TgeneF10P00742DB13152Coagulation Factor IX HumanActivatorBiotechApproved
TgeneF10P00742DB13192Antihemophilic factor humanActivatorBiotechApproved
TgeneF10P00742DB13884Albutrepenonacog alfaActivatorBiotechApproved
TgeneF10P00742DB13999Moroctocog alfaActivatorBiotechApproved
TgeneF10P00742DB14738Turoctocog alfa pegolActivatorBiotechApproved
TgeneF10P00742DB00025Antihemophilic factor, human recombinantActivatorBiotechApproved|Investigational
TgeneF10P00742DB00100Coagulation Factor IX (Recombinant)ActivatorBiotechApproved|Investigational
TgeneF10P00742DB00569FondaparinuxInhibitorSmall moleculeApproved|Investigational
TgeneF10P00742DB01109HeparinInhibitorSmall moleculeApproved|Investigational
TgeneF10P00742DB09109Turoctocog alfaActivatorBiotechApproved|Investigational
TgeneF10P00742DB09258BemiparinAntagonistSmall moleculeApproved|Investigational
TgeneF10P00742DB11166Antithrombin AlfaInhibitorBiotechApproved|Investigational
TgeneF10P00742DB12364BetrixabanInhibitorSmall moleculeApproved|Investigational
TgeneF10P00742DB13150Coagulation factor VII humanActivatorBiotechApproved|Investigational
TgeneF10P00742DB13151Anti-inhibitor coagulant complexAgonistBiotechApproved|Investigational
TgeneF10P00742DB13923EmicizumabActivatorBiotechApproved|Investigational
TgeneF10P00742DB13933Nonacog beta pegolAgonistBiotechApproved|Investigational
TgeneF10P00742DB13998Lonoctocog alfaActivatorBiotechApproved|Investigational

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Related Diseases for RNF19A-F10


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneF10C0015519Factor X Deficiency32CLINGEN;CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneF10C0272327Hereditary factor X deficiency disease11CLINGEN
TgeneF10C0005779Blood Coagulation Disorders1CTD_human
TgeneF10C0040053Thrombosis1CTD_human
TgeneF10C0087086Thrombus1CTD_human