FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:RNF43-AKAP9 (FusionGDB2 ID:74642)

Fusion Gene Summary for RNF43-AKAP9

check button Fusion gene summary
Fusion gene informationFusion gene name: RNF43-AKAP9
Fusion gene ID: 74642
HgeneTgene
Gene symbol

RNF43

AKAP9

Gene ID

54894

10142

Gene namering finger protein 43A-kinase anchoring protein 9
SynonymsRNF124|SSPCS|URCCAKAP-9|AKAP350|AKAP450|CG-NAP|HYPERION|LQT11|MU-RMS-40.16A|PPP1R45|PRKA9|YOTIAO
Cytomap

17q22

7q21.2

Type of geneprotein-codingprotein-coding
DescriptionE3 ubiquitin-protein ligase RNF43RING-type E3 ubiquitin transferase RNF43A-kinase anchor protein 9A kinase (PRKA) anchor protein (yotiao) 9A kinase (PRKA) anchor protein 9A-kinase anchor protein 350 kDaA-kinase anchor protein 450 kDaAKAP 120-like proteinAKAP9-BRAF fusion proteincentrosome- and Golgi-localized PKN-associ
Modification date2020031320200328
UniProtAcc.

Q99996

Ensembl transtripts involved in fusion geneENST00000500597, ENST00000407977, 
ENST00000583753, ENST00000584437, 
ENST00000577716, ENST00000581868, 
ENST00000577625, ENST00000580014, 
ENST00000356239, ENST00000358100, 
ENST00000359028, ENST00000394564, 
ENST00000491695, 
Fusion gene scores* DoF score12 X 10 X 7=84011 X 17 X 7=1309
# samples 1315
** MAII scorelog2(13/840*10)=-2.69187770463767
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/1309*10)=-3.12543069144936
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RNF43 [Title/Abstract] AND AKAP9 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRNF43(56492686)-AKAP9(91674321), # samples:1
Anticipated loss of major functional domain due to fusion event.RNF43-AKAP9 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
RNF43-AKAP9 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneRNF43

GO:0006511

ubiquitin-dependent protein catabolic process

22895187

HgeneRNF43

GO:0016567

protein ubiquitination

22575959

HgeneRNF43

GO:0038018

Wnt receptor catabolic process

22895187

TgeneAKAP9

GO:0098962

regulation of postsynaptic neurotransmitter receptor activity

10390370

TgeneAKAP9

GO:1903358

regulation of Golgi organization

27666745


check buttonFusion gene breakpoints across RNF43 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across AKAP9 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-HU-A4H5RNF43chr17

56492686

-AKAP9chr7

91674321

+


Top

Fusion Gene ORF analysis for RNF43-AKAP9

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000500597ENST00000356239RNF43chr17

56492686

-AKAP9chr7

91674321

+
In-frameENST00000500597ENST00000358100RNF43chr17

56492686

-AKAP9chr7

91674321

+
In-frameENST00000500597ENST00000359028RNF43chr17

56492686

-AKAP9chr7

91674321

+
5CDS-intronENST00000500597ENST00000394564RNF43chr17

56492686

-AKAP9chr7

91674321

+
5CDS-intronENST00000500597ENST00000491695RNF43chr17

56492686

-AKAP9chr7

91674321

+
In-frameENST00000407977ENST00000356239RNF43chr17

56492686

-AKAP9chr7

91674321

+
In-frameENST00000407977ENST00000358100RNF43chr17

56492686

-AKAP9chr7

91674321

+
In-frameENST00000407977ENST00000359028RNF43chr17

56492686

-AKAP9chr7

91674321

+
5CDS-intronENST00000407977ENST00000394564RNF43chr17

56492686

-AKAP9chr7

91674321

+
5CDS-intronENST00000407977ENST00000491695RNF43chr17

56492686

-AKAP9chr7

91674321

+
Frame-shiftENST00000583753ENST00000356239RNF43chr17

56492686

-AKAP9chr7

91674321

+
Frame-shiftENST00000583753ENST00000358100RNF43chr17

56492686

-AKAP9chr7

91674321

+
Frame-shiftENST00000583753ENST00000359028RNF43chr17

56492686

-AKAP9chr7

91674321

+
5CDS-intronENST00000583753ENST00000394564RNF43chr17

56492686

-AKAP9chr7

91674321

+
5CDS-intronENST00000583753ENST00000491695RNF43chr17

56492686

-AKAP9chr7

91674321

+
Frame-shiftENST00000584437ENST00000356239RNF43chr17

56492686

-AKAP9chr7

91674321

+
Frame-shiftENST00000584437ENST00000358100RNF43chr17

56492686

-AKAP9chr7

91674321

+
Frame-shiftENST00000584437ENST00000359028RNF43chr17

56492686

-AKAP9chr7

91674321

+
5CDS-intronENST00000584437ENST00000394564RNF43chr17

56492686

-AKAP9chr7

91674321

+
5CDS-intronENST00000584437ENST00000491695RNF43chr17

56492686

-AKAP9chr7

91674321

+
Frame-shiftENST00000577716ENST00000356239RNF43chr17

56492686

-AKAP9chr7

91674321

+
Frame-shiftENST00000577716ENST00000358100RNF43chr17

56492686

-AKAP9chr7

91674321

+
Frame-shiftENST00000577716ENST00000359028RNF43chr17

56492686

-AKAP9chr7

91674321

+
5CDS-intronENST00000577716ENST00000394564RNF43chr17

56492686

-AKAP9chr7

91674321

+
5CDS-intronENST00000577716ENST00000491695RNF43chr17

56492686

-AKAP9chr7

91674321

+
intron-3CDSENST00000581868ENST00000356239RNF43chr17

56492686

-AKAP9chr7

91674321

+
intron-3CDSENST00000581868ENST00000358100RNF43chr17

56492686

-AKAP9chr7

91674321

+
intron-3CDSENST00000581868ENST00000359028RNF43chr17

56492686

-AKAP9chr7

91674321

+
intron-intronENST00000581868ENST00000394564RNF43chr17

56492686

-AKAP9chr7

91674321

+
intron-intronENST00000581868ENST00000491695RNF43chr17

56492686

-AKAP9chr7

91674321

+
intron-3CDSENST00000577625ENST00000356239RNF43chr17

56492686

-AKAP9chr7

91674321

+
intron-3CDSENST00000577625ENST00000358100RNF43chr17

56492686

-AKAP9chr7

91674321

+
intron-3CDSENST00000577625ENST00000359028RNF43chr17

56492686

-AKAP9chr7

91674321

+
intron-intronENST00000577625ENST00000394564RNF43chr17

56492686

-AKAP9chr7

91674321

+
intron-intronENST00000577625ENST00000491695RNF43chr17

56492686

-AKAP9chr7

91674321

+
intron-3CDSENST00000580014ENST00000356239RNF43chr17

56492686

-AKAP9chr7

91674321

+
intron-3CDSENST00000580014ENST00000358100RNF43chr17

56492686

-AKAP9chr7

91674321

+
intron-3CDSENST00000580014ENST00000359028RNF43chr17

56492686

-AKAP9chr7

91674321

+
intron-intronENST00000580014ENST00000394564RNF43chr17

56492686

-AKAP9chr7

91674321

+
intron-intronENST00000580014ENST00000491695RNF43chr17

56492686

-AKAP9chr7

91674321

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000500597RNF43chr1756492686-ENST00000356239AKAP9chr791674321+781674077173012176
ENST00000500597RNF43chr1756492686-ENST00000358100AKAP9chr791674321+763074077171152114
ENST00000500597RNF43chr1756492686-ENST00000359028AKAP9chr791674321+779274077172772168
ENST00000407977RNF43chr1756492686-ENST00000356239AKAP9chr791674321+8049973100475342176
ENST00000407977RNF43chr1756492686-ENST00000358100AKAP9chr791674321+7863973100473482114
ENST00000407977RNF43chr1756492686-ENST00000359028AKAP9chr791674321+8025973100475102168

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000500597ENST00000356239RNF43chr1756492686-AKAP9chr791674321+0.0052578930.99474204
ENST00000500597ENST00000358100RNF43chr1756492686-AKAP9chr791674321+0.0052513790.99474865
ENST00000500597ENST00000359028RNF43chr1756492686-AKAP9chr791674321+0.004723870.9952761
ENST00000407977ENST00000356239RNF43chr1756492686-AKAP9chr791674321+0.0059496760.9940503
ENST00000407977ENST00000358100RNF43chr1756492686-AKAP9chr791674321+0.0059369510.9940631
ENST00000407977ENST00000359028RNF43chr1756492686-AKAP9chr791674321+0.0053606490.99463934

Top

Fusion Genomic Features for RNF43-AKAP9


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
RNF43chr1756492686-AKAP9chr791674321+2.22E-050.9999778
RNF43chr1756492686-AKAP9chr791674321+2.22E-050.9999778

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for RNF43-AKAP9


check button Go to

FGviewer for the breakpoints of chr17:56492686-chr7:91674321

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.AKAP9

Q99996

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Scaffolding protein that assembles several protein kinases and phosphatases on the centrosome and Golgi apparatus. Required to maintain the integrity of the Golgi apparatus (PubMed:10202149, PubMed:15047863). Required for microtubule nucleation at the cis-side of the Golgi apparatus (PubMed:15047863, PubMed:19242490). Required for association of the centrosomes with the poles of the bipolar mitotic spindle during metaphase (PubMed:25657325). In complex with PDE4DIP isoform 13/MMG8/SMYLE, recruits CAMSAP2 to the Golgi apparatus and tethers non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement (PubMed:27666745, PubMed:28814570). In complex with PDE4DIP isoform 13/MMG8/SMYLE, EB1/MAPRE1 and CDK5RAP2, contributes to microtubules nucleation and extension also from the centrosome to the cell periphery (PubMed:29162697). {ECO:0000269|PubMed:10202149, ECO:0000269|PubMed:15047863, ECO:0000269|PubMed:19242490, ECO:0000269|PubMed:25657325, ECO:0000269|PubMed:27666745, ECO:0000269|PubMed:28814570, ECO:0000269|PubMed:29162697}.; FUNCTION: [Isoform 4]: Associated with the N-methyl-D-aspartate receptor and is specifically found in the neuromuscular junction (NMJ) as well as in neuronal synapses, suggesting a role in the organization of postsynaptic specializations. {ECO:0000269|PubMed:9482789}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035623919501845_24431720.66666666666673908.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035623919502532_25491720.66666666666673908.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035623919502591_27641720.66666666666673908.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035623919503061_30881720.66666666666673908.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035623919503120_34661720.66666666666673908.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035623919503583_36851720.66666666666673908.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035810020491845_24431732.66666666666673858.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035810020492532_25491732.66666666666673858.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035810020492591_27641732.66666666666673858.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035810020493061_30881732.66666666666673858.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035810020493120_34661732.66666666666673858.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035810020493583_36851732.66666666666673858.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035902820501845_24431732.66666666666673912.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035902820502532_25491732.66666666666673912.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035902820502591_27641732.66666666666673912.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035902820503061_30881732.66666666666673912.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035902820503120_34661732.66666666666673912.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035902820503583_36851732.66666666666673912.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035623919501834_27601720.66666666666673908.0Compositional biasNote=Glu-rich
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035623919503722_37261720.66666666666673908.0Compositional biasNote=Poly-Leu
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035810020491834_27601732.66666666666673858.0Compositional biasNote=Glu-rich
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035810020493722_37261732.66666666666673858.0Compositional biasNote=Poly-Leu
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035902820501834_27601732.66666666666673912.0Compositional biasNote=Glu-rich
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035902820503722_37261732.66666666666673912.0Compositional biasNote=Poly-Leu
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035623919502542_25551720.66666666666673908.0RegionNote=PKA-RII subunit binding domain
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035810020492542_25551732.66666666666673858.0RegionNote=PKA-RII subunit binding domain
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035902820502542_25551732.66666666666673912.0RegionNote=PKA-RII subunit binding domain

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRNF43chr17:56492686chr7:91674321ENST00000407977-210443_50384.0784.0Compositional biasNote=Ser-rich
HgeneRNF43chr17:56492686chr7:91674321ENST00000407977-210547_55784.0784.0Compositional biasNote=His-rich
HgeneRNF43chr17:56492686chr7:91674321ENST00000407977-210569_76084.0784.0Compositional biasNote=Pro-rich
HgeneRNF43chr17:56492686chr7:91674321ENST00000500597-29443_50384.0743.0Compositional biasNote=Ser-rich
HgeneRNF43chr17:56492686chr7:91674321ENST00000500597-29547_55784.0743.0Compositional biasNote=His-rich
HgeneRNF43chr17:56492686chr7:91674321ENST00000500597-29569_76084.0743.0Compositional biasNote=Pro-rich
HgeneRNF43chr17:56492686chr7:91674321ENST00000577625-19443_5030657.0Compositional biasNote=Ser-rich
HgeneRNF43chr17:56492686chr7:91674321ENST00000577625-19547_5570657.0Compositional biasNote=His-rich
HgeneRNF43chr17:56492686chr7:91674321ENST00000577625-19569_7600657.0Compositional biasNote=Pro-rich
HgeneRNF43chr17:56492686chr7:91674321ENST00000577716-210443_50384.0784.0Compositional biasNote=Ser-rich
HgeneRNF43chr17:56492686chr7:91674321ENST00000577716-210547_55784.0784.0Compositional biasNote=His-rich
HgeneRNF43chr17:56492686chr7:91674321ENST00000577716-210569_76084.0784.0Compositional biasNote=Pro-rich
HgeneRNF43chr17:56492686chr7:91674321ENST00000583753-18443_50384.0743.0Compositional biasNote=Ser-rich
HgeneRNF43chr17:56492686chr7:91674321ENST00000583753-18547_55784.0743.0Compositional biasNote=His-rich
HgeneRNF43chr17:56492686chr7:91674321ENST00000583753-18569_76084.0743.0Compositional biasNote=Pro-rich
HgeneRNF43chr17:56492686chr7:91674321ENST00000584437-19443_50384.0784.0Compositional biasNote=Ser-rich
HgeneRNF43chr17:56492686chr7:91674321ENST00000584437-19547_55784.0784.0Compositional biasNote=His-rich
HgeneRNF43chr17:56492686chr7:91674321ENST00000584437-19569_76084.0784.0Compositional biasNote=Pro-rich
HgeneRNF43chr17:56492686chr7:91674321ENST00000407977-210219_78384.0784.0Topological domainCytoplasmic
HgeneRNF43chr17:56492686chr7:91674321ENST00000407977-21024_19784.0784.0Topological domainExtracellular
HgeneRNF43chr17:56492686chr7:91674321ENST00000500597-29219_78384.0743.0Topological domainCytoplasmic
HgeneRNF43chr17:56492686chr7:91674321ENST00000500597-2924_19784.0743.0Topological domainExtracellular
HgeneRNF43chr17:56492686chr7:91674321ENST00000577625-19219_7830657.0Topological domainCytoplasmic
HgeneRNF43chr17:56492686chr7:91674321ENST00000577625-1924_1970657.0Topological domainExtracellular
HgeneRNF43chr17:56492686chr7:91674321ENST00000577716-210219_78384.0784.0Topological domainCytoplasmic
HgeneRNF43chr17:56492686chr7:91674321ENST00000577716-21024_19784.0784.0Topological domainExtracellular
HgeneRNF43chr17:56492686chr7:91674321ENST00000583753-18219_78384.0743.0Topological domainCytoplasmic
HgeneRNF43chr17:56492686chr7:91674321ENST00000583753-1824_19784.0743.0Topological domainExtracellular
HgeneRNF43chr17:56492686chr7:91674321ENST00000584437-19219_78384.0784.0Topological domainCytoplasmic
HgeneRNF43chr17:56492686chr7:91674321ENST00000584437-1924_19784.0784.0Topological domainExtracellular
HgeneRNF43chr17:56492686chr7:91674321ENST00000407977-210198_21884.0784.0TransmembraneHelical
HgeneRNF43chr17:56492686chr7:91674321ENST00000500597-29198_21884.0743.0TransmembraneHelical
HgeneRNF43chr17:56492686chr7:91674321ENST00000577625-19198_2180657.0TransmembraneHelical
HgeneRNF43chr17:56492686chr7:91674321ENST00000577716-210198_21884.0784.0TransmembraneHelical
HgeneRNF43chr17:56492686chr7:91674321ENST00000583753-18198_21884.0743.0TransmembraneHelical
HgeneRNF43chr17:56492686chr7:91674321ENST00000584437-19198_21884.0784.0TransmembraneHelical
HgeneRNF43chr17:56492686chr7:91674321ENST00000407977-210272_31384.0784.0Zinc fingerRING-type%3B atypical
HgeneRNF43chr17:56492686chr7:91674321ENST00000500597-29272_31384.0743.0Zinc fingerRING-type%3B atypical
HgeneRNF43chr17:56492686chr7:91674321ENST00000577625-19272_3130657.0Zinc fingerRING-type%3B atypical
HgeneRNF43chr17:56492686chr7:91674321ENST00000577716-210272_31384.0784.0Zinc fingerRING-type%3B atypical
HgeneRNF43chr17:56492686chr7:91674321ENST00000583753-18272_31384.0743.0Zinc fingerRING-type%3B atypical
HgeneRNF43chr17:56492686chr7:91674321ENST00000584437-19272_31384.0784.0Zinc fingerRING-type%3B atypical
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035623919501088_11731720.66666666666673908.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035623919501241_12681720.66666666666673908.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035623919501324_13801720.66666666666673908.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035623919501422_14471720.66666666666673908.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST000003562391950152_9021720.66666666666673908.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035623919501573_16471720.66666666666673908.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST000003562391950932_10101720.66666666666673908.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035810020491088_11731732.66666666666673858.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035810020491241_12681732.66666666666673858.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035810020491324_13801732.66666666666673858.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035810020491422_14471732.66666666666673858.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST000003581002049152_9021732.66666666666673858.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035810020491573_16471732.66666666666673858.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST000003581002049932_10101732.66666666666673858.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035902820501088_11731732.66666666666673912.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035902820501241_12681732.66666666666673912.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035902820501324_13801732.66666666666673912.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035902820501422_14471732.66666666666673912.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST000003590282050152_9021732.66666666666673912.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST0000035902820501573_16471732.66666666666673912.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST000003590282050932_10101732.66666666666673912.0Coiled coilOntology_term=ECO:0000255
TgeneAKAP9chr17:56492686chr7:91674321ENST000003562391950191_2801720.66666666666673908.0Compositional biasNote=Gln-rich
TgeneAKAP9chr17:56492686chr7:91674321ENST000003562391950309_9981720.66666666666673908.0Compositional biasNote=Glu-rich
TgeneAKAP9chr17:56492686chr7:91674321ENST000003581002049191_2801732.66666666666673858.0Compositional biasNote=Gln-rich
TgeneAKAP9chr17:56492686chr7:91674321ENST000003581002049309_9981732.66666666666673858.0Compositional biasNote=Glu-rich
TgeneAKAP9chr17:56492686chr7:91674321ENST000003590282050191_2801732.66666666666673912.0Compositional biasNote=Gln-rich
TgeneAKAP9chr17:56492686chr7:91674321ENST000003590282050309_9981732.66666666666673912.0Compositional biasNote=Glu-rich


Top

Fusion Gene Sequence for RNF43-AKAP9


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000500597_ENST00000356239_TCGA-HU-A4H5_RNF43_chr17_56492686_-_AKAP9_chr7_91674321_length(transcript)=7816nt_BP=740nt
GTACTTGGTTAAGCAGTTGAAACCTTTTTTGAGCAGGATCTGTAAAAGCATAATTGAATTTGTTTCACCCCCGTGGATTCCAGTGGGCCC
GACAGCGCAACAGTGCCTGGCAACTTGATGCATATGGAAGAGCAATGCCAAGTGATCTGACATAATACAAATTCACGAAGTGACATTCAA
TCACAAGCAAAGTTGGAAATTCCAAAGAGAAGTGGTGAGATCTTTACTAGTCACAGTGAAGATGGGAGAAAATGACATACCTGCAGCAGA
TGTGGGCTGAAAATATCCTCTTCTCTGCCCAATCAGGAATGCTACCTGTTTTTGGGAATAAACTTTAGAGAAAGGAAGGGCCAAAACTAC
GACTTGGCTTTCTGAAACGGAAGCATAAATGTTCTTTTCCTCCATTTGTCTGGATCTGAGAACCTGCATTTGGTATTAGCTAGTGGAAGC
AGTATGTATGGTTGAAGTGCATTGCTGCAGCTGGTAGCATGAGTGGTGGCCACCAGCTGCAGCTGGCTGCCCTCTGGCCCTGGCTGCTGA
TGGCTACCCTGCAGGCAGGCTTTGGACGCACAGGACTGGTACTGGCAGCAGCGGTGGAGTCTGAAAGATCAGCAGAACAGAAAGCTATTA
TCAGAGTGATCCCCTTGAAAATGGACCCCACAGGAAAACTGAATCTCACTTTGGAAGGTGTGTTTGCTGGTGTTGCTGAAATAACTCCAG
CAGAAGGAAAATTAATGCAGGTATGCACTCCAGAAAGCTAATAATAGACTTTTGAAGATCCTCTTAGAAGTTGTAAAGACAACAGCAGCT
GTTGAAGAAACAATTGGTCGCCATGTCCTTGGGATTCTAGATAGATCTAGTAAAAGCCAGTCATCTGCCAGCCTAATTTGGAGGTCAGAA
GCAGAGGCATCTGTAAAGTCATGTGTCCATGAGGAACATACAAGAGTTACAGATGAATCCATTCCCTCTTATTCTGGAAGTGATATGCCA
AGAAATGACATTAACATGTGGTCAAAAGTAACTGAGGAAGGAACAGAGCTGTCACAACGACTTGTGAGGAGTGGTTTTGCTGGAACTGAA
ATAGACCCTGAAAATGAAGAACTTATGCTGAACATTAGCTCTCGACTACAAGCAGCAGTTGAAAAACTCCTAGAAGCCATAAGTGAAACT
AGCAGTCAGCTTGAACATGCGAAAGTGACACAGACAGAGTTGATGCGTGAGTCATTTAGACAGAAACAAGAAGCAACAGAGTCCCTTAAG
TGCCAAGAGGAACTTCGAGAGCGCCTTCATGAGGAGTCCAGGGCCAGAGAACAGCTAGCTGTGGAGCTCAGTAAGGCTGAGGGCGTCATT
GATGGCTATGCAGATGAAAAAACTCTTTTTGAAAGGCAAATTCAGGAAAAAACTGATATAATAGATCGTCTTGAGCAGGAGTTGTTATGT
GCAAGTAACAGGTTGCAAGAATTGGAGGCAGAGCAACAGCAGATCCAAGAAGAAAGAGAATTACTGTCCAGACAAAAGGAAGCTATGAAA
GCAGAGGCAGGCCCAGTTGAACAACAATTACTACAGGAGACAGAAAAATTAATGAAGGAAAAACTAGAAGTACAATGTCAAGCTGAAAAA
GTACGTGATGACCTTCAAAAACAAGTGAAAGCTCTAGAAATAGATGTGGAAGAACAAGTCAGTAGGTTTATAGAGCTGGAACAAGAAAAA
AATACTGAACTAATGGATTTAAGACAGCAAAACCAAGCATTGGAAAAGCAGTTAGAAAAAATGAGAAAATTTTTAGATGAGCAAGCCATT
GACAGAGAACATGAGAGAGATGTATTCCAACAGGAAATACAGAAACTAGAACAGCAACTTAAGGTTGTTCCTCGATTCCAGCCTATCAGT
GAACATCAAACTAGAGAGGTTGAACAGTTAGCAAATCATCTGAAAGAAAAAACAGACAAATGCAGTGAGCTTTTGCTCTCTAAAGAGCAG
CTTCAAAGGGATATACAAGAAAGGAATGAAGAAATAGAGAAACTGGAGTTCAGAGTAAGAGAACTGGAGCAGGCGCTTCTTGTGAGTGCA
GATACTTTTCAAAAGGTAGAGGACCGAAAACACTTTGGAGCTGTAGAAGCTAAACCAGAATTGTCCCTAGAAGTACAATTGCAGGCTGAA
CGAGATGCCATAGACAGAAAGGAAAAAGAGATTACAAACTTAGAAGAGCAATTAGAACAGTTTAGAGAAGAACTGGAAAATAAGAATGAA
GAAGTTCAACAATTACATATGCAATTAGAAATACAGAAAAAGGAATCTACTACCCGCCTACAAGAACTTGAACAGGAAAACAAATTATTT
AAGGATGACATGGAGAAACTGGGACTTGCCATAAAGGAATCTGATGCCATGTCTACTCAAGACCAACATGTGCTATTTGGGAAATTTGCT
CAAATAATACAGGAAAAAGAGGTAGAAATTGACCAATTAAATGAACAAGTTACGAAACTCCAGCAGCAACTTAAAATTACAACAGATAAC
AAGGTTATTGAAGAAAAAAATGAACTGATAAGGGATCTTGAAACCCAAATAGAATGTTTGATGAGTGATCAAGAATGTGTGAAGAGAAAT
AGAGAAGAAGAAATAGAGCAGCTCAATGAAGTGATTGAAAAACTTCAACAGGAATTGGCAAATATTGGACAGAAGACATCAATGAATGCT
CATTCCCTCTCAGAAGAAGCAGACAGTTTAAAACATCAATTGGATGTGGTTATAGCTGAAAAGCTGGCCTTGGAACAGCAAGTAGAAACC
GCTAATGAAGAAATGACCTTCATGAAAAATGTACTTAAAGAAACCAATTTTAAAATGAATCAGCTAACACAGGAATTATTCAGCTTAAAG
AGAGAACGTGAAAGTGTGGAAAAGATTCAAAGCATACCAGAGAATAGTGTTAACGTGGCTATAGATCATCTGAGCAAAGACAAACCTGAA
CTAGAAGTAGTCCTTACAGAGGATGCTCTTAAATCCCTAGAAAATCAGACATACTTCAAATCTTTTGAAGAAAATGGCAAAGGTTCCATA
ATTAATTTGGAAACAAGGTTGCTACAACTTGAGAGCACTGTTAGTGCAAAGGACTTAGAACTTACCCAGTGTTATAAACAAATAAAAGAC
ATGCAAGAACAAGGCCAGTTTGAAACAGAAATGCTTCAAAAGAAGATTGTAAACCTACAGAAAATAGTTGAAGAAAAAGTGGCTGCTGCT
CTTGTCAGTCAAATCCAACTTGAGGCAGTTCAGGAATATGCAAAATTCTGTCAAGATAATCAAACAATTTCATCAGAACCTGAAAGAACA
AATATTCAGAATTTAAATCAACTAAGAGAAGATGAGTTGGGGTCAGATATATCAGCATTAACCTTGAGAATATCAGAATTAGAAAGCCAG
GTTGTTGAAATGCATACTAGTTTGATTTTAGAAAAAGAACAAGTAGAAATTGCAGAAAAAAATGTTTTAGAAAAAGAAAAGAAGCTGCTA
GAACTACAGAAGCTATTGGAGGGCAATGAGAAAAAACAGAGAGAGAAAGAAAAGAAAAGAAGCCCTCAAGATGTTGAAGTTCTCAAGACA
ACTACTGAGCTATTTCATAGCAATGAAGAAAGTGGATTTTTTAATGAACTCGAGGCTCTTAGAGCTGAATCAGTGGCTACCAAAGCAGAA
CTTGCCAGTTATAAAGAAAAGGCTGAAAAACTTCAAGAAGAGCTTTTGGTAAAAGAAACAAATATGACATCTCTTCAGAAAGACTTAAGC
CAAGTTAGGGATCACCTCGCAGAGGCAAAAGAGAAATTGTCCATTTTAGAAAAAGAAGATGAGACTGAGGTACAAGAAAGCAAAAAGGCC
TGCATGTTTGAGCCACTTCCTATAAAACTGAGTAAGAGCATTGCATCCCAGACAGATGGGACTCTGAAGATCAGTAGCAGCAATCAGACT
CCACAAATTCTTGTTAAAAATGCAGGAATACAAATTAATTTACAGAGTGAATGTTCCTCAGAAGAAGTTACTGAAATAATCAGTCAGTTT
ACTGAAAAAATTGAGAAGATGCAAGAACTACATGCTGCTGAAATTTTGGACATGGAATCCAGACATATTTCAGAAACTGAAACCTTAAAG
AGGGAACACTATGTTGCCGTTCAGTTACTGAAAGAGGAATGTGGTACCTTGAAGGCAGTGATACAGTGTCTGAGAAGTAAAGAGGGATCC
TCAATTCCTGAGCTAGCACATTCTGATGCTTACCAGACTAGAGAAATATGCTCCAGTGATTCTGGATCAGACTGGGGTCAGGGAATTTAT
CTTACACACAGTCAGGGATTTGACATAGCATCAGAAGGCCGAGGAGAAGAAAGTGAAAGTGCAACAGATTCCTTTCCAAAGAAAATAAAG
GGATTACTGAGAGCTGTCCATAATGAAGGCATGCAGGTGCTTTCTCTCACTGAGTCTCCCTATAGTGATGGAGAGGACCATTCTATTCAG
CAGGTTTCAGAACCTTGGCTAGAAGAGAGAAAAGCTTACATCAATACAATCTCATCTCTAAAGGATTTAATTACAAAGATGCAACTGCAA
AGAGAAGCCGAGGTTTATGATAGTTCTCAATCTCATGAGAGCTTCTCAGACTGGCGAGGTGAACTACTGCTTGCCCTTCAACAAGTTTTC
TTAGAAGAGCGTAGTGTTTTACTAGCAGCATTTCGGACGGAGCTGACAGCTCTAGGTACTACAGATGCAGTTGGTTTACTAAACTGTTTG
GAACAGAGAATACAAGAACAGGGTGTTGAATATCAAGCAGCTATGGAATGCCTCCAGAAAGCAGATAGAAGGAGTTTGTTATCTGAAATT
CAGGCACTGCATGCACAAATGAATGGTAGGAAAATTACTCTGAAAAGAGAACAAGAGAGTGAGAAACCAAGCCAAGAACTCTTGGAATAT
AATATACAGCAGAAGCAGTCTCAAATGCTGGAGATGCAAGTGGAGCTCAGCAGTATGAAAGACAGAGCAACGGAACTGCAGGAGCAGCTG
AGTTCTGAGAAAATGGTGGTTGCTGAACTGAAGAGTGAGCTTGCACAAACTAAATTGGAACTAGAAACAACACTCAAGGCACAGCATAAA
CACCTAAAAGAATTGGAGGCTTTCAGGTTGGAAGTTAAAGATAAGACAGATGAAGTACATTTGCTTAATGACACATTAGCAAGTGAACAG
AAAAAATCAAGAGAGCTCCAGTGGGCTTTGGAGAAAGAGAAAGCCAAGTTGGGACGCAGTGAAGAACGGGATAAAGAAGAACTTGAGGAT
CTGAAGTTTTCACTTGAGAGTCAGAAACAAAGGAATCTTCAGCTAAATCTACTTTTGGAACAACAGAAACAACTACTGAACGAATCCCAG
CAAAAAATAGAATCACAGAGAATGCTATATGATGCCCAGTTGTCAGAAGAACAAGGTCGAAACTTAGAGCTTCAGGTACTTCTTGAATCT
GAGAAAGTTCGAATTCGGGAAATGAGTAGTACCCTAGATAGGGAGCGGGAATTGCACGCACAGCTGCAGAGCAGTGATGGTACTGGACAG
TCTCGGCCACCCTTGCCCTCAGAGGACCTACTGAAAGAGCTGCAGAAACAGCTAGAGGAAAAACACAGTCGCATAGTAGAATTGTTAAAT
GAGACTGAAAAATATAAACTGGATTCTTTGCAAACACGACAGCAAATGGAAAAAGATAGGCAGGTTCACAGGAAAACACTGCAGACAGAA
CAGGAGGCCAACACTGAGGGACAGAAAAAAATGCATGAGCTCCAGTCCAAAGTGGAAGATCTTCAGCGCCAGCTGGAAGAGAAAAGACAA
CAAGTTTATAAGTTAGACCTTGAAGGACAGCGACTACAAGGAATCATGCAGGAATTCCAGAAGCAAGAACTAGAACGAGAAGAAAAACGA
GAAAGTAGAAGAATTCTGTATCAGAACCTTAATGAGCCAACCACGTGGAGCTTAACCAGTGATAGAACTAGAAATTGGGTTCTTCAACAG
AAAATAGAAGGAGAAACAAAAGAATCAAACTACGCTAAATTGATTGAAATGAATGGAGGAGGAACCGGCTGTAATCATGAATTAGAAATG
ATCAGACAAAAGCTTCAATGTGTAGCTTCAAAACTACAGGTTCTACCCCAGAAAGCCTCTGAGAGACTACAGTTTGAAACAGCAGATGAT
GAAGATTTCATTTGGGTTCAGGAAAATATTGATGAAATTATTTTACAACTACAGAAATTAACTGGCCAGCAAGGTGAAGAGCCCAGCTTG
GTGTCCCCAAGTACTTCTTGTGGCTCATTGACTGAAAGACTACTGAGACAAAATGCTGAGCTGACAGGGCATATCAGTCAACTGACTGAA
GAGAAGAATGACTTAAGGAACATGGTTATGAAGCTGGAAGAGCAGATCAGGTGGTATCGACAGACAGGAGCTGGTAGAGATAATTCTTCC
AGGTTTTCATTGAATGGTGGTGCCAACATTGAAGCCATCATTGCCTCTGAAAAAGAAGTATGGAACAGAGAAAAATTGACTCTCCAGAAA
TCTTTGAAAAGGGCAGAGGCTGAAGTATACAAACTGAAAGCTGAACTAAGAAATGACTCTTTACTTCAAACTCTGAGCCCTGATTCTGAA
CATGTCACTTTAAAGAGAATTTATGGTAAATACTTGAGGGCAGAAAGTTTTCGAAAGGCTCTCATTTACCAGAAGAAATACCTGCTGCTG
TTACTGGGTGGGTTCCAGGAATGTGAAGATGCCACCTTGGCCCTGCTTGCCCGGATGGGGGGGCAGCCAGCTTTCACGGATCTAGAGGTG
ATCACCAATCGCCCAAAGGGCTTCACCAGGTTTCGGTCGGCCGTCAGAGTATCCATTGCAATTTCCAGAATGAAATTTTTGGTTCGACGG
TGGCATCGAGTCACAGGTTCTGTTTCCATCAATATTAACAGAGATGGCTTTGGACTGAATCAAGGTGCAGAAAAGACTGACTCATTTTAT
CATTCTTCTGGTGGGCTGGAGTTATATGGAGAACCAAGACATACTACGTATCGCTCAAGATCAGATCTGGACTATATTAGGTCCCCTTTA
CCATTTCAGAATAGGTACCCAGGCACTCCAGCTGATTTCAATCCTGGTTCTTTAGCATGTTCTCAGCTTCAGAATTACGATCCTGACAGA
GCCCTAACAGATTATATCACTCGGCTAGAGGCACTGCAAAGACGACTTGGAACTATACAGTCAGGTTCAACTACTCAATTTCATGCTGGC
ATGAGAAGATAATCCTTTGAAACATCATTAATTGAAGTGATTTTAAATAGATTTCCTTTTGTAAATCAATGGTTCTTTTGTGCTTTTGTA
TTGTGAATATTCAATGGGACCAATATGAACACAGCTTATGATTGTATACAAATCCCTTGCCAGCACATGAAAACAAACTGGAATTTGTAT
ATATAAGCATTGTGTATGTATTCATGCACAATAATTATTGAATTACCTGTATATTTGTGGAATGCTAATTTAAAACATTAAATTATAAAC
CTTGTGTATTTATCAAATGGGTGAAAAGATTAAACTTTTACGCATTACAATACTGCTGAATGTGTAGCTCGAGGTGTCCTGCACTTTTCT
TATAAGGCTACTGAAGTTACATGTTTTGCCTAATATATTCTACTGGTGATGAAGACAGATAATATCACTTGTAGAGACCTATTTTTGTAT

>In-frame_ENST00000500597_ENST00000356239_TCGA-HU-A4H5_RNF43_chr17_56492686_-_AKAP9_chr7_91674321_length(amino acids)=2176AA_start in transcript=771_stop in transcript=7301
MKILLEVVKTTAAVEETIGRHVLGILDRSSKSQSSASLIWRSEAEASVKSCVHEEHTRVTDESIPSYSGSDMPRNDINMWSKVTEEGTEL
SQRLVRSGFAGTEIDPENEELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEELRERLHEESRARE
QLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKL
MKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLE
QQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEA
KPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAM
STQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQ
ELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSV
NVAIDHLSKDKPELEVVLTEDALKSLENQTYFKSFEENGKGSIINLETRLLQLESTVSAKDLELTQCYKQIKDMQEQGQFETEMLQKKIV
NLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLREDELGSDISALTLRISELESQVVEMHTSLILEKEQVEI
AEKNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQEELLV
KETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQESKKACMFEPLPIKLSKSIASQTDGTLKISSSNQTPQILVKNAGIQINLQSE
CSSEEVTEIISQFTEKIEKMQELHAAEILDMESRHISETETLKREHYVAVQLLKEECGTLKAVIQCLRSKEGSSIPELAHSDAYQTREIC
SSDSGSDWGQGIYLTHSQGFDIASEGRGEESESATDSFPKKIKGLLRAVHNEGMQVLSLTESPYSDGEDHSIQQVSEPWLEERKAYINTI
SSLKDLITKMQLQREAEVYDSSQSHESFSDWRGELLLALQQVFLEERSVLLAAFRTELTALGTTDAVGLLNCLEQRIQEQGVEYQAAMEC
LQKADRRSLLSEIQALHAQMNGRKITLKREQESEKPSQELLEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQT
KLELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNL
LLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKELQKQ
LEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQGIMQ
EFQKQELEREEKRESRRILYQNLNEPTTWSLTSDRTRNWVLQQKIEGETKESNYAKLIEMNGGGTGCNHELEMIRQKLQCVASKLQVLPQ
KASERLQFETADDEDFIWVQENIDEIILQLQKLTGQQGEEPSLVSPSTSCGSLTERLLRQNAELTGHISQLTEEKNDLRNMVMKLEEQIR
WYRQTGAGRDNSSRFSLNGGANIEAIIASEKEVWNREKLTLQKSLKRAEAEVYKLKAELRNDSLLQTLSPDSEHVTLKRIYGKYLRAESF
RKALIYQKKYLLLLLGGFQECEDATLALLARMGGQPAFTDLEVITNRPKGFTRFRSAVRVSIAISRMKFLVRRWHRVTGSVSININRDGF
GLNQGAEKTDSFYHSSGGLELYGEPRHTTYRSRSDLDYIRSPLPFQNRYPGTPADFNPGSLACSQLQNYDPDRALTDYITRLEALQRRLG

--------------------------------------------------------------
>In-frame_ENST00000500597_ENST00000358100_TCGA-HU-A4H5_RNF43_chr17_56492686_-_AKAP9_chr7_91674321_length(transcript)=7630nt_BP=740nt
GTACTTGGTTAAGCAGTTGAAACCTTTTTTGAGCAGGATCTGTAAAAGCATAATTGAATTTGTTTCACCCCCGTGGATTCCAGTGGGCCC
GACAGCGCAACAGTGCCTGGCAACTTGATGCATATGGAAGAGCAATGCCAAGTGATCTGACATAATACAAATTCACGAAGTGACATTCAA
TCACAAGCAAAGTTGGAAATTCCAAAGAGAAGTGGTGAGATCTTTACTAGTCACAGTGAAGATGGGAGAAAATGACATACCTGCAGCAGA
TGTGGGCTGAAAATATCCTCTTCTCTGCCCAATCAGGAATGCTACCTGTTTTTGGGAATAAACTTTAGAGAAAGGAAGGGCCAAAACTAC
GACTTGGCTTTCTGAAACGGAAGCATAAATGTTCTTTTCCTCCATTTGTCTGGATCTGAGAACCTGCATTTGGTATTAGCTAGTGGAAGC
AGTATGTATGGTTGAAGTGCATTGCTGCAGCTGGTAGCATGAGTGGTGGCCACCAGCTGCAGCTGGCTGCCCTCTGGCCCTGGCTGCTGA
TGGCTACCCTGCAGGCAGGCTTTGGACGCACAGGACTGGTACTGGCAGCAGCGGTGGAGTCTGAAAGATCAGCAGAACAGAAAGCTATTA
TCAGAGTGATCCCCTTGAAAATGGACCCCACAGGAAAACTGAATCTCACTTTGGAAGGTGTGTTTGCTGGTGTTGCTGAAATAACTCCAG
CAGAAGGAAAATTAATGCAGGTATGCACTCCAGAAAGCTAATAATAGACTTTTGAAGATCCTCTTAGAAGTTGTAAAGACAACAGCAGCT
GTTGAAGAAACAATTGGTCGCCATGTCCTTGGGATTCTAGATAGATCTAGTAAAAGCCAGTCATCTGCCAGCCTAATTTGGAGGTCAGAA
GCAGAGGCATCTGTAAAGTCATGTGTCCATGAGGAACATACAAGAGTTACAGATGAATCCATTCCCTCTTATTCTGGAAGTGATATGCCA
AGAAATGACATTAACATGTGGTCAAAAGTAACTGAGGAAGGAACAGAGCTGTCACAACGACTTGTGAGGAGTGGTTTTGCTGGAACTGAA
ATAGACCCTGAAAATGAAGAACTTATGCTGAACATTAGCTCTCGACTACAAGCAGCAGTTGAAAAACTCCTAGAAGCCATAAGTGAAACT
AGCAGTCAGCTTGAACATGCGAAAGTGACACAGACAGAGTTGATGCGTGAGTCATTTAGACAGAAACAAGAAGCAACAGAGTCCCTTAAG
TGCCAAGAGGAACTTCGAGAGCGCCTTCATGAGGAGTCCAGGGCCAGAGAACAGCTAGCTGTGGAGCTCAGTAAGGCTGAGGGCGTCATT
GATGGCTATGCAGATGAAAAAACTCTTTTTGAAAGGCAAATTCAGGAAAAAACTGATATAATAGATCGTCTTGAGCAGGAGTTGTTATGT
GCAAGTAACAGGTTGCAAGAATTGGAGGCAGAGCAACAGCAGATCCAAGAAGAAAGAGAATTACTGTCCAGACAAAAGGAAGCTATGAAA
GCAGAGGCAGGCCCAGTTGAACAACAATTACTACAGGAGACAGAAAAATTAATGAAGGAAAAACTAGAAGTACAATGTCAAGCTGAAAAA
GTACGTGATGACCTTCAAAAACAAGTGAAAGCTCTAGAAATAGATGTGGAAGAACAAGTCAGTAGGTTTATAGAGCTGGAACAAGAAAAA
AATACTGAACTAATGGATTTAAGACAGCAAAACCAAGCATTGGAAAAGCAGTTAGAAAAAATGAGAAAATTTTTAGATGAGCAAGCCATT
GACAGAGAACATGAGAGAGATGTATTCCAACAGGAAATACAGAAACTAGAACAGCAACTTAAGGTTGTTCCTCGATTCCAGCCTATCAGT
GAACATCAAACTAGAGAGGTTGAACAGTTAGCAAATCATCTGAAAGAAAAAACAGACAAATGCAGTGAGCTTTTGCTCTCTAAAGAGCAG
CTTCAAAGGGATATACAAGAAAGGAATGAAGAAATAGAGAAACTGGAGTTCAGAGTAAGAGAACTGGAGCAGGCGCTTCTTGTGAGTGCA
GATACTTTTCAAAAGGTAGAGGACCGAAAACACTTTGGAGCTGTAGAAGCTAAACCAGAATTGTCCCTAGAAGTACAATTGCAGGCTGAA
CGAGATGCCATAGACAGAAAGGAAAAAGAGATTACAAACTTAGAAGAGCAATTAGAACAGTTTAGAGAAGAACTGGAAAATAAGAATGAA
GAAGTTCAACAATTACATATGCAATTAGAAATACAGAAAAAGGAATCTACTACCCGCCTACAAGAACTTGAACAGGAAAACAAATTATTT
AAGGATGACATGGAGAAACTGGGACTTGCCATAAAGGAATCTGATGCCATGTCTACTCAAGACCAACATGTGCTATTTGGGAAATTTGCT
CAAATAATACAGGAAAAAGAGGTAGAAATTGACCAATTAAATGAACAAGTTACGAAACTCCAGCAGCAACTTAAAATTACAACAGATAAC
AAGGTTATTGAAGAAAAAAATGAACTGATAAGGGATCTTGAAACCCAAATAGAATGTTTGATGAGTGATCAAGAATGTGTGAAGAGAAAT
AGAGAAGAAGAAATAGAGCAGCTCAATGAAGTGATTGAAAAACTTCAACAGGAATTGGCAAATATTGGACAGAAGACATCAATGAATGCT
CATTCCCTCTCAGAAGAAGCAGACAGTTTAAAACATCAATTGGATGTGGTTATAGCTGAAAAGCTGGCCTTGGAACAGCAAGTAGAAACC
GCTAATGAAGAAATGACCTTCATGAAAAATGTACTTAAAGAAACCAATTTTAAAATGAATCAGCTAACACAGGAATTATTCAGCTTAAAG
AGAGAACGTGAAAGTGTGGAAAAGATTCAAAGCATACCAGAGAATAGTGTTAACGTGGCTATAGATCATCTGAGCAAAGACAAACCTGAA
CTAGAAGTAGTCCTTACAGAGGATGCTCTTAAATCCCTAGAAAATCAGACATACTTCAAATCTTTTGAAGAAAATGGCAAAGGTTCCATA
ATTAATTTGGAAACAAGGTTGCTACAACTTGAGAGCACTGTTAGTGCAAAGGACTTAGAACTTACCCAGTGTTATAAACAAATAAAAGAC
ATGCAAGAACAAGGCCAGTTTGAAACAGAAATGCTTCAAAAGAAGATTGTAAACCTACAGAAAATAGTTGAAGAAAAAGTGGCTGCTGCT
CTTGTCAGTCAAATCCAACTTGAGGCAGTTCAGGAATATGCAAAATTCTGTCAAGATAATCAAACAATTTCATCAGAACCTGAAAGAACA
AATATTCAGAATTTAAATCAACTAAGAGAAGATGAGTTGGGGTCAGATATATCAGCATTAACCTTGAGAATATCAGAATTAGAAAGCCAG
GTTGTTGAAATGCATACTAGTTTGATTTTAGAAAAAGAACAAGTAGAAATTGCAGAAAAAAATGTTTTAGAAAAAGAAAAGAAGCTGCTA
GAACTACAGAAGCTATTGGAGGGCAATGAGAAAAAACAGAGAGAGAAAGAAAAGAAAAGAAGCCCTCAAGATGTTGAAGTTCTCAAGACA
ACTACTGAGCTATTTCATAGCAATGAAGAAAGTGGATTTTTTAATGAACTCGAGGCTCTTAGAGCTGAATCAGTGGCTACCAAAGCAGAA
CTTGCCAGTTATAAAGAAAAGGCTGAAAAACTTCAAGAAGAGCTTTTGGTAAAAGAAACAAATATGACATCTCTTCAGAAAGACTTAAGC
CAAGTTAGGGATCACCTCGCAGAGGCAAAAGAGAAATTGTCCATTTTAGAAAAAGAAGATGAGACTGAGGTACAAGAAAGCAAAAAGGCC
TGCATGTTTGAGCCACTTCCTATAAAACTGAGTAAGAGCATTGCATCCCAGACAGATGGGACTCTGAAGATCAGTAGCAGCAATCAGACT
CCACAAATTCTTGTTAAAAATGCAGGAATACAAATTAATTTACAGAGTGAATGTTCCTCAGAAGAAGTTACTGAAATAATCAGTCAGTTT
ACTGAAAAAATTGAGAAGATGCAAGAACTACATGCTGCTGAAATTTTGGACATGGAATCCAGACATATTTCAGAAACTGAAACCTTAAAG
AGGGAACACTATGTTGCCGTTCAGTTACTGAAAGAGGAATGTGGTACCTTGAAGGCAGTGATACAGTGTCTGAGAAGTAAAGAGGGATTA
CTGAGAGCTGTCCATAATGAAGGCATGCAGGTGCTTTCTCTCACTGAGTCTCCCTATAGTGATGGAGAGGACCATTCTATTCAGCAGGTT
TCAGAACCTTGGCTAGAAGAGAGAAAAGCTTACATCAATACAATCTCATCTCTAAAGGATTTAATTACAAAGATGCAACTGCAAAGAGAA
GCCGAGGTTTATGATAGTTCTCAATCTCATGAGAGCTTCTCAGACTGGCGAGGTGAACTACTGCTTGCCCTTCAACAAGTTTTCTTAGAA
GAGCGTAGTGTTTTACTAGCAGCATTTCGGACGGAGCTGACAGCTCTAGGTACTACAGATGCAGTTGGTTTACTAAACTGTTTGGAACAG
AGAATACAAGAACAGGGTGTTGAATATCAAGCAGCTATGGAATGCCTCCAGAAAGCAGATAGAAGGAGTTTGTTATCTGAAATTCAGGCA
CTGCATGCACAAATGAATGGTAGGAAAATTACTCTGAAAAGAGAACAAGAGAGTGAGAAACCAAGCCAAGAACTCTTGGAATATAATATA
CAGCAGAAGCAGTCTCAAATGCTGGAGATGCAAGTGGAGCTCAGCAGTATGAAAGACAGAGCAACGGAACTGCAGGAGCAGCTGAGTTCT
GAGAAAATGGTGGTTGCTGAACTGAAGAGTGAGCTTGCACAAACTAAATTGGAACTAGAAACAACACTCAAGGCACAGCATAAACACCTA
AAAGAATTGGAGGCTTTCAGGTTGGAAGTTAAAGATAAGACAGATGAAGTACATTTGCTTAATGACACATTAGCAAGTGAACAGAAAAAA
TCAAGAGAGCTCCAGTGGGCTTTGGAGAAAGAGAAAGCCAAGTTGGGACGCAGTGAAGAACGGGATAAAGAAGAACTTGAGGATCTGAAG
TTTTCACTTGAGAGTCAGAAACAAAGGAATCTTCAGCTAAATCTACTTTTGGAACAACAGAAACAACTACTGAACGAATCCCAGCAAAAA
ATAGAATCACAGAGAATGCTATATGATGCCCAGTTGTCAGAAGAACAAGGTCGAAACTTAGAGCTTCAGGTACTTCTTGAATCTGAGAAA
GTTCGAATTCGGGAAATGAGTAGTACCCTAGATAGGGAGCGGGAATTGCACGCACAGCTGCAGAGCAGTGATGGTACTGGACAGTCTCGG
CCACCCTTGCCCTCAGAGGACCTACTGAAAGAGCTGCAGAAACAGCTAGAGGAAAAACACAGTCGCATAGTAGAATTGTTAAATGAGACT
GAAAAATATAAACTGGATTCTTTGCAAACACGACAGCAAATGGAAAAAGATAGGCAGGTTCACAGGAAAACACTGCAGACAGAACAGGAG
GCCAACACTGAGGGACAGAAAAAAATGCATGAGCTCCAGTCCAAAGTGGAAGATCTTCAGCGCCAGCTGGAAGAGAAAAGACAACAAGTT
TATAAGTTAGACCTTGAAGGACAGCGACTACAAGGAATCATGCAGGAATTCCAGAAGCAAGAACTAGAACGAGAAGAAAAACGAGAAAGT
AGAAGAATTCTGTATCAGAACCTTAATGAGCCAACCACGTGGAGCTTAACCAGTGATAGAACTAGAAATTGGGTTCTTCAACAGAAAATA
GAAGGAGAAACAAAAGAATCAAACTACGCTAAATTGATTGAAATGAATGGAGGAGGAACCGGCTGTAATCATGAATTAGAAATGATCAGA
CAAAAGCTTCAATGTGTAGCTTCAAAACTACAGGTTCTACCCCAGAAAGCCTCTGAGAGACTACAGTTTGAAACAGCAGATGATGAAGAT
TTCATTTGGGTTCAGGAAAATATTGATGAAATTATTTTACAACTACAGAAATTAACTGGCCAGCAAGGTGAAGAGCCCAGCTTGGTGTCC
CCAAGTACTTCTTGTGGCTCATTGACTGAAAGACTACTGAGACAAAATGCTGAGCTGACAGGGCATATCAGTCAACTGACTGAAGAGAAG
AATGACTTAAGGAACATGGTTATGAAGCTGGAAGAGCAGATCAGGTGGTATCGACAGACAGGAGCTGGTAGAGATAATTCTTCCAGGTTT
TCATTGAATGGTGGTGCCAACATTGAAGCCATCATTGCCTCTGAAAAAGAAGTATGGAACAGAGAAAAATTGACTCTCCAGAAATCTTTG
AAAAGGGCAGAGGCTGAAGTATACAAACTGAAAGCTGAACTAAGAAATGACTCTTTACTTCAAACTCTGAGCCCTGATTCTGAACATGTC
ACTTTAAAGAGAATTTATGGTAAATACTTGAGGGCAGAAAGTTTTCGAAAGGCTCTCATTTACCAGAAGAAATACCTGCTGCTGTTACTG
GGTGGGTTCCAGGAATGTGAAGATGCCACCTTGGCCCTGCTTGCCCGGATGGGGGGGCAGCCAGCTTTCACGGATCTAGAGGTGATCACC
AATCGCCCAAAGGGCTTCACCAGGTTTCGGTCGGCCGTCAGAGTATCCATTGCAATTTCCAGAATGAAATTTTTGGTTCGACGGTGGCAT
CGAGTCACAGGTTCTGTTTCCATCAATATTAACAGAGATGGCTTTGGACTGAATCAAGGTGCAGAAAAGACTGACTCATTTTATCATTCT
TCTGGTGGGCTGGAGTTATATGGAGAACCAAGACATACTACGTATCGCTCAAGATCAGATCTGGACTATATTAGGTCCCCTTTACCATTT
CAGAATAGGTACCCAGGCACTCCAGCTGATTTCAATCCTGGTTCTTTAGCATGTTCTCAGCTTCAGAATTACGATCCTGACAGAGCCCTA
ACAGATTATATCACTCGGCTAGAGGCACTGCAAAGACGACTTGGAACTATACAGTCAGGTTCAACTACTCAATTTCATGCTGGCATGAGA
AGATAATCCTTTGAAACATCATTAATTGAAGTGATTTTAAATAGATTTCCTTTTGTAAATCAATGGTTCTTTTGTGCTTTTGTATTGTGA
ATATTCAATGGGACCAATATGAACACAGCTTATGATTGTATACAAATCCCTTGCCAGCACATGAAAACAAACTGGAATTTGTATATATAA
GCATTGTGTATGTATTCATGCACAATAATTATTGAATTACCTGTATATTTGTGGAATGCTAATTTAAAACATTAAATTATAAACCTTGTG
TATTTATCAAATGGGTGAAAAGATTAAACTTTTACGCATTACAATACTGCTGAATGTGTAGCTCGAGGTGTCCTGCACTTTTCTTATAAG
GCTACTGAAGTTACATGTTTTGCCTAATATATTCTACTGGTGATGAAGACAGATAATATCACTTGTAGAGACCTATTTTTGTATAATGGT

>In-frame_ENST00000500597_ENST00000358100_TCGA-HU-A4H5_RNF43_chr17_56492686_-_AKAP9_chr7_91674321_length(amino acids)=2114AA_start in transcript=771_stop in transcript=7115
MKILLEVVKTTAAVEETIGRHVLGILDRSSKSQSSASLIWRSEAEASVKSCVHEEHTRVTDESIPSYSGSDMPRNDINMWSKVTEEGTEL
SQRLVRSGFAGTEIDPENEELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEELRERLHEESRARE
QLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKL
MKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLE
QQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEA
KPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAM
STQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQ
ELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSV
NVAIDHLSKDKPELEVVLTEDALKSLENQTYFKSFEENGKGSIINLETRLLQLESTVSAKDLELTQCYKQIKDMQEQGQFETEMLQKKIV
NLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLREDELGSDISALTLRISELESQVVEMHTSLILEKEQVEI
AEKNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQEELLV
KETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQESKKACMFEPLPIKLSKSIASQTDGTLKISSSNQTPQILVKNAGIQINLQSE
CSSEEVTEIISQFTEKIEKMQELHAAEILDMESRHISETETLKREHYVAVQLLKEECGTLKAVIQCLRSKEGLLRAVHNEGMQVLSLTES
PYSDGEDHSIQQVSEPWLEERKAYINTISSLKDLITKMQLQREAEVYDSSQSHESFSDWRGELLLALQQVFLEERSVLLAAFRTELTALG
TTDAVGLLNCLEQRIQEQGVEYQAAMECLQKADRRSLLSEIQALHAQMNGRKITLKREQESEKPSQELLEYNIQQKQSQMLEMQVELSSM
KDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGR
SEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDRERELH
AQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVE
DLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQELEREEKRESRRILYQNLNEPTTWSLTSDRTRNWVLQQKIEGETKESNYAKLIEMNG
GGTGCNHELEMIRQKLQCVASKLQVLPQKASERLQFETADDEDFIWVQENIDEIILQLQKLTGQQGEEPSLVSPSTSCGSLTERLLRQNA
ELTGHISQLTEEKNDLRNMVMKLEEQIRWYRQTGAGRDNSSRFSLNGGANIEAIIASEKEVWNREKLTLQKSLKRAEAEVYKLKAELRND
SLLQTLSPDSEHVTLKRIYGKYLRAESFRKALIYQKKYLLLLLGGFQECEDATLALLARMGGQPAFTDLEVITNRPKGFTRFRSAVRVSI
AISRMKFLVRRWHRVTGSVSININRDGFGLNQGAEKTDSFYHSSGGLELYGEPRHTTYRSRSDLDYIRSPLPFQNRYPGTPADFNPGSLA

--------------------------------------------------------------
>In-frame_ENST00000500597_ENST00000359028_TCGA-HU-A4H5_RNF43_chr17_56492686_-_AKAP9_chr7_91674321_length(transcript)=7792nt_BP=740nt
GTACTTGGTTAAGCAGTTGAAACCTTTTTTGAGCAGGATCTGTAAAAGCATAATTGAATTTGTTTCACCCCCGTGGATTCCAGTGGGCCC
GACAGCGCAACAGTGCCTGGCAACTTGATGCATATGGAAGAGCAATGCCAAGTGATCTGACATAATACAAATTCACGAAGTGACATTCAA
TCACAAGCAAAGTTGGAAATTCCAAAGAGAAGTGGTGAGATCTTTACTAGTCACAGTGAAGATGGGAGAAAATGACATACCTGCAGCAGA
TGTGGGCTGAAAATATCCTCTTCTCTGCCCAATCAGGAATGCTACCTGTTTTTGGGAATAAACTTTAGAGAAAGGAAGGGCCAAAACTAC
GACTTGGCTTTCTGAAACGGAAGCATAAATGTTCTTTTCCTCCATTTGTCTGGATCTGAGAACCTGCATTTGGTATTAGCTAGTGGAAGC
AGTATGTATGGTTGAAGTGCATTGCTGCAGCTGGTAGCATGAGTGGTGGCCACCAGCTGCAGCTGGCTGCCCTCTGGCCCTGGCTGCTGA
TGGCTACCCTGCAGGCAGGCTTTGGACGCACAGGACTGGTACTGGCAGCAGCGGTGGAGTCTGAAAGATCAGCAGAACAGAAAGCTATTA
TCAGAGTGATCCCCTTGAAAATGGACCCCACAGGAAAACTGAATCTCACTTTGGAAGGTGTGTTTGCTGGTGTTGCTGAAATAACTCCAG
CAGAAGGAAAATTAATGCAGGTATGCACTCCAGAAAGCTAATAATAGACTTTTGAAGATCCTCTTAGAAGTTGTAAAGACAACAGCAGCT
GTTGAAGAAACAATTGGTCGCCATGTCCTTGGGATTCTAGATAGATCTAGTAAAAGCCAGTCATCTGCCAGCCTAATTTGGAGGTCAGAA
GCAGAGGCATCTGTAAAGTCATGTGTCCATGAGGAACATACAAGAGTTACAGATGAATCCATTCCCTCTTATTCTGGAAGTGATATGCCA
AGAAATGACATTAACATGTGGTCAAAAGTAACTGAGGAAGGAACAGAGCTGTCACAACGACTTGTGAGGAGTGGTTTTGCTGGAACTGAA
ATAGACCCTGAAAATGAAGAACTTATGCTGAACATTAGCTCTCGACTACAAGCAGCAGTTGAAAAACTCCTAGAAGCCATAAGTGAAACT
AGCAGTCAGCTTGAACATGCGAAAGTGACACAGACAGAGTTGATGCGTGAGTCATTTAGACAGAAACAAGAAGCAACAGAGTCCCTTAAG
TGCCAAGAGGAACTTCGAGAGCGCCTTCATGAGGAGTCCAGGGCCAGAGAACAGCTAGCTGTGGAGCTCAGTAAGGCTGAGGGCGTCATT
GATGGCTATGCAGATGAAAAAACTCTTTTTGAAAGGCAAATTCAGGAAAAAACTGATATAATAGATCGTCTTGAGCAGGAGTTGTTATGT
GCAAGTAACAGGTTGCAAGAATTGGAGGCAGAGCAACAGCAGATCCAAGAAGAAAGAGAATTACTGTCCAGACAAAAGGAAGCTATGAAA
GCAGAGGCAGGCCCAGTTGAACAACAATTACTACAGGAGACAGAAAAATTAATGAAGGAAAAACTAGAAGTACAATGTCAAGCTGAAAAA
GTACGTGATGACCTTCAAAAACAAGTGAAAGCTCTAGAAATAGATGTGGAAGAACAAGTCAGTAGGTTTATAGAGCTGGAACAAGAAAAA
AATACTGAACTAATGGATTTAAGACAGCAAAACCAAGCATTGGAAAAGCAGTTAGAAAAAATGAGAAAATTTTTAGATGAGCAAGCCATT
GACAGAGAACATGAGAGAGATGTATTCCAACAGGAAATACAGAAACTAGAACAGCAACTTAAGGTTGTTCCTCGATTCCAGCCTATCAGT
GAACATCAAACTAGAGAGGTTGAACAGTTAGCAAATCATCTGAAAGAAAAAACAGACAAATGCAGTGAGCTTTTGCTCTCTAAAGAGCAG
CTTCAAAGGGATATACAAGAAAGGAATGAAGAAATAGAGAAACTGGAGTTCAGAGTAAGAGAACTGGAGCAGGCGCTTCTTGTGAGTGCA
GATACTTTTCAAAAGGTAGAGGACCGAAAACACTTTGGAGCTGTAGAAGCTAAACCAGAATTGTCCCTAGAAGTACAATTGCAGGCTGAA
CGAGATGCCATAGACAGAAAGGAAAAAGAGATTACAAACTTAGAAGAGCAATTAGAACAGTTTAGAGAAGAACTGGAAAATAAGAATGAA
GAAGTTCAACAATTACATATGCAATTAGAAATACAGAAAAAGGAATCTACTACCCGCCTACAAGAACTTGAACAGGAAAACAAATTATTT
AAGGATGACATGGAGAAACTGGGACTTGCCATAAAGGAATCTGATGCCATGTCTACTCAAGACCAACATGTGCTATTTGGGAAATTTGCT
CAAATAATACAGGAAAAAGAGGTAGAAATTGACCAATTAAATGAACAAGTTACGAAACTCCAGCAGCAACTTAAAATTACAACAGATAAC
AAGGTTATTGAAGAAAAAAATGAACTGATAAGGGATCTTGAAACCCAAATAGAATGTTTGATGAGTGATCAAGAATGTGTGAAGAGAAAT
AGAGAAGAAGAAATAGAGCAGCTCAATGAAGTGATTGAAAAACTTCAACAGGAATTGGCAAATATTGGACAGAAGACATCAATGAATGCT
CATTCCCTCTCAGAAGAAGCAGACAGTTTAAAACATCAATTGGATGTGGTTATAGCTGAAAAGCTGGCCTTGGAACAGCAAGTAGAAACC
GCTAATGAAGAAATGACCTTCATGAAAAATGTACTTAAAGAAACCAATTTTAAAATGAATCAGCTAACACAGGAATTATTCAGCTTAAAG
AGAGAACGTGAAAGTGTGGAAAAGATTCAAAGCATACCAGAGAATAGTGTTAACGTGGCTATAGATCATCTGAGCAAAGACAAACCTGAA
CTAGAAGTAGTCCTTACAGAGGATGCTCTTAAATCCCTAGAAAATCAGACATACTTCAAATCTTTTGAAGAAAATGGCAAAGGTTCCATA
ATTAATTTGGAAACAAGGTTGCTACAACTTGAGAGCACTGTTAGTGCAAAGGACTTAGAACTTACCCAGTGTTATAAACAAATAAAAGAC
ATGCAAGAACAAGGCCAGTTTGAAACAGAAATGCTTCAAAAGAAGATTGTAAACCTACAGAAAATAGTTGAAGAAAAAGTGGCTGCTGCT
CTTGTCAGTCAAATCCAACTTGAGGCAGTTCAGGAATATGCAAAATTCTGTCAAGATAATCAAACAATTTCATCAGAACCTGAAAGAACA
AATATTCAGAATTTAAATCAACTAAGAGAAGATGAGTTGGGGTCAGATATATCAGCATTAACCTTGAGAATATCAGAATTAGAAAGCCAG
GTTGTTGAAATGCATACTAGTTTGATTTTAGAAAAAGAACAAGTAGAAATTGCAGAAAAAAATGTTTTAGAAAAAGAAAAGAAGCTGCTA
GAACTACAGAAGCTATTGGAGGGCAATGAGAAAAAACAGAGAGAGAAAGAAAAGAAAAGAAGCCCTCAAGATGTTGAAGTTCTCAAGACA
ACTACTGAGCTATTTCATAGCAATGAAGAAAGTGGATTTTTTAATGAACTCGAGGCTCTTAGAGCTGAATCAGTGGCTACCAAAGCAGAA
CTTGCCAGTTATAAAGAAAAGGCTGAAAAACTTCAAGAAGAGCTTTTGGTAAAAGAAACAAATATGACATCTCTTCAGAAAGACTTAAGC
CAAGTTAGGGATCACCTCGCAGAGGCAAAAGAGAAATTGTCCATTTTAGAAAAAGAAGATGAGACTGAGGTACAAGAAAGCAAAAAGGCC
TGCATGTTTGAGCCACTTCCTATAAAACTGAGTAAGAGCATTGCATCCCAGACAGATGGGACTCTGAAGATCAGTAGCAGCAATCAGACT
CCACAAATTCTTGTTAAAAATGCAGGAATACAAATTAATTTACAGAGTGAATGTTCCTCAGAAGAAGTTACTGAAATAATCAGTCAGTTT
ACTGAAAAAATTGAGAAGATGCAAGAACTACATGCTGCTGAAATTTTGGACATGGAATCCAGACATATTTCAGAAACTGAAACCTTAAAG
AGGGAACACTATGTTGCCGTTCAGTTACTGAAAGAGGAATGTGGTACCTTGAAGGCAGTGATACAGTGTCTGAGAAGTAAAGAGGTATTT
GGTTTTTATAATATGTGTTTTTCAACATTGTGTGATTCTGGATCAGACTGGGGTCAGGGAATTTATCTTACACACAGTCAGGGATTTGAC
ATAGCATCAGAAGGCCGAGGAGAAGAAAGTGAAAGTGCAACAGATTCCTTTCCAAAGAAAATAAAGGGATTACTGAGAGCTGTCCATAAT
GAAGGCATGCAGGTGCTTTCTCTCACTGAGTCTCCCTATAGTGATGGAGAGGACCATTCTATTCAGCAGGTTTCAGAACCTTGGCTAGAA
GAGAGAAAAGCTTACATCAATACAATCTCATCTCTAAAGGATTTAATTACAAAGATGCAACTGCAAAGAGAAGCCGAGGTTTATGATAGT
TCTCAATCTCATGAGAGCTTCTCAGACTGGCGAGGTGAACTACTGCTTGCCCTTCAACAAGTTTTCTTAGAAGAGCGTAGTGTTTTACTA
GCAGCATTTCGGACGGAGCTGACAGCTCTAGGTACTACAGATGCAGTTGGTTTACTAAACTGTTTGGAACAGAGAATACAAGAACAGGGT
GTTGAATATCAAGCAGCTATGGAATGCCTCCAGAAAGCAGATAGAAGGAGTTTGTTATCTGAAATTCAGGCACTGCATGCACAAATGAAT
GGTAGGAAAATTACTCTGAAAAGAGAACAAGAGAGTGAGAAACCAAGCCAAGAACTCTTGGAATATAATATACAGCAGAAGCAGTCTCAA
ATGCTGGAGATGCAAGTGGAGCTCAGCAGTATGAAAGACAGAGCAACGGAACTGCAGGAGCAGCTGAGTTCTGAGAAAATGGTGGTTGCT
GAACTGAAGAGTGAGCTTGCACAAACTAAATTGGAACTAGAAACAACACTCAAGGCACAGCATAAACACCTAAAAGAATTGGAGGCTTTC
AGGTTGGAAGTTAAAGATAAGACAGATGAAGTACATTTGCTTAATGACACATTAGCAAGTGAACAGAAAAAATCAAGAGAGCTCCAGTGG
GCTTTGGAGAAAGAGAAAGCCAAGTTGGGACGCAGTGAAGAACGGGATAAAGAAGAACTTGAGGATCTGAAGTTTTCACTTGAGAGTCAG
AAACAAAGGAATCTTCAGCTAAATCTACTTTTGGAACAACAGAAACAACTACTGAACGAATCCCAGCAAAAAATAGAATCACAGAGAATG
CTATATGATGCCCAGTTGTCAGAAGAACAAGGTCGAAACTTAGAGCTTCAGGTACTTCTTGAATCTGAGAAAGTTCGAATTCGGGAAATG
AGTAGTACCCTAGATAGGGAGCGGGAATTGCACGCACAGCTGCAGAGCAGTGATGGTACTGGACAGTCTCGGCCACCCTTGCCCTCAGAG
GACCTACTGAAAGAGCTGCAGAAACAGCTAGAGGAAAAACACAGTCGCATAGTAGAATTGTTAAATGAGACTGAAAAATATAAACTGGAT
TCTTTGCAAACACGACAGCAAATGGAAAAAGATAGGCAGGTTCACAGGAAAACACTGCAGACAGAACAGGAGGCCAACACTGAGGGACAG
AAAAAAATGCATGAGCTCCAGTCCAAAGTGGAAGATCTTCAGCGCCAGCTGGAAGAGAAAAGACAACAAGTTTATAAGTTAGACCTTGAA
GGACAGCGACTACAAGGAATCATGCAGGAATTCCAGAAGCAAGAACTAGAACGAGAAGAAAAACGAGAAAGTAGAAGAATTCTGTATCAG
AACCTTAATGAGCCAACCACGTGGAGCTTAACCAGTGATAGAACTAGAAATTGGGTTCTTCAACAGAAAATAGAAGGAGAAACAAAAGAA
TCAAACTACGCTAAATTGATTGAAATGAATGGAGGAGGAACCGGCTGTAATCATGAATTAGAAATGATCAGACAAAAGCTTCAATGTGTA
GCTTCAAAACTACAGGTTCTACCCCAGAAAGCCTCTGAGAGACTACAGTTTGAAACAGCAGATGATGAAGATTTCATTTGGGTTCAGGAA
AATATTGATGAAATTATTTTACAACTACAGAAATTAACTGGCCAGCAAGGTGAAGAGCCCAGCTTGGTGTCCCCAAGTACTTCTTGTGGC
TCATTGACTGAAAGACTACTGAGACAAAATGCTGAGCTGACAGGGCATATCAGTCAACTGACTGAAGAGAAGAATGACTTAAGGAACATG
GTTATGAAGCTGGAAGAGCAGATCAGGTGGTATCGACAGACAGGAGCTGGTAGAGATAATTCTTCCAGGTTTTCATTGAATGGTGGTGCC
AACATTGAAGCCATCATTGCCTCTGAAAAAGAAGTATGGAACAGAGAAAAATTGACTCTCCAGAAATCTTTGAAAAGGGCAGAGGCTGAA
GTATACAAACTGAAAGCTGAACTAAGAAATGACTCTTTACTTCAAACTCTGAGCCCTGATTCTGAACATGTCACTTTAAAGAGAATTTAT
GGTAAATACTTGAGGGCAGAAAGTTTTCGAAAGGCTCTCATTTACCAGAAGAAATACCTGCTGCTGTTACTGGGTGGGTTCCAGGAATGT
GAAGATGCCACCTTGGCCCTGCTTGCCCGGATGGGGGGGCAGCCAGCTTTCACGGATCTAGAGGTGATCACCAATCGCCCAAAGGGCTTC
ACCAGGTTTCGGTCGGCCGTCAGAGTATCCATTGCAATTTCCAGAATGAAATTTTTGGTTCGACGGTGGCATCGAGTCACAGGTTCTGTT
TCCATCAATATTAACAGAGATGGCTTTGGACTGAATCAAGGTGCAGAAAAGACTGACTCATTTTATCATTCTTCTGGTGGGCTGGAGTTA
TATGGAGAACCAAGACATACTACGTATCGCTCAAGATCAGATCTGGACTATATTAGGTCCCCTTTACCATTTCAGAATAGGTACCCAGGC
ACTCCAGCTGATTTCAATCCTGGTTCTTTAGCATGTTCTCAGCTTCAGAATTACGATCCTGACAGAGCCCTAACAGATTATATCACTCGG
CTAGAGGCACTGCAAAGACGACTTGGAACTATACAGTCAGGTTCAACTACTCAATTTCATGCTGGCATGAGAAGATAATCCTTTGAAACA
TCATTAATTGAAGTGATTTTAAATAGATTTCCTTTTGTAAATCAATGGTTCTTTTGTGCTTTTGTATTGTGAATATTCAATGGGACCAAT
ATGAACACAGCTTATGATTGTATACAAATCCCTTGCCAGCACATGAAAACAAACTGGAATTTGTATATATAAGCATTGTGTATGTATTCA
TGCACAATAATTATTGAATTACCTGTATATTTGTGGAATGCTAATTTAAAACATTAAATTATAAACCTTGTGTATTTATCAAATGGGTGA
AAAGATTAAACTTTTACGCATTACAATACTGCTGAATGTGTAGCTCGAGGTGTCCTGCACTTTTCTTATAAGGCTACTGAAGTTACATGT
TTTGCCTAATATATTCTACTGGTGATGAAGACAGATAATATCACTTGTAGAGACCTATTTTTGTATAATGGTAGAAGTTTTGAATTTTAT

>In-frame_ENST00000500597_ENST00000359028_TCGA-HU-A4H5_RNF43_chr17_56492686_-_AKAP9_chr7_91674321_length(amino acids)=2168AA_start in transcript=771_stop in transcript=7277
MKILLEVVKTTAAVEETIGRHVLGILDRSSKSQSSASLIWRSEAEASVKSCVHEEHTRVTDESIPSYSGSDMPRNDINMWSKVTEEGTEL
SQRLVRSGFAGTEIDPENEELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEELRERLHEESRARE
QLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKL
MKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLE
QQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEA
KPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAM
STQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQ
ELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSV
NVAIDHLSKDKPELEVVLTEDALKSLENQTYFKSFEENGKGSIINLETRLLQLESTVSAKDLELTQCYKQIKDMQEQGQFETEMLQKKIV
NLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLREDELGSDISALTLRISELESQVVEMHTSLILEKEQVEI
AEKNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQEELLV
KETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQESKKACMFEPLPIKLSKSIASQTDGTLKISSSNQTPQILVKNAGIQINLQSE
CSSEEVTEIISQFTEKIEKMQELHAAEILDMESRHISETETLKREHYVAVQLLKEECGTLKAVIQCLRSKEVFGFYNMCFSTLCDSGSDW
GQGIYLTHSQGFDIASEGRGEESESATDSFPKKIKGLLRAVHNEGMQVLSLTESPYSDGEDHSIQQVSEPWLEERKAYINTISSLKDLIT
KMQLQREAEVYDSSQSHESFSDWRGELLLALQQVFLEERSVLLAAFRTELTALGTTDAVGLLNCLEQRIQEQGVEYQAAMECLQKADRRS
LLSEIQALHAQMNGRKITLKREQESEKPSQELLEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTL
KAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQL
LNESQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHSRI
VELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQELE
REEKRESRRILYQNLNEPTTWSLTSDRTRNWVLQQKIEGETKESNYAKLIEMNGGGTGCNHELEMIRQKLQCVASKLQVLPQKASERLQF
ETADDEDFIWVQENIDEIILQLQKLTGQQGEEPSLVSPSTSCGSLTERLLRQNAELTGHISQLTEEKNDLRNMVMKLEEQIRWYRQTGAG
RDNSSRFSLNGGANIEAIIASEKEVWNREKLTLQKSLKRAEAEVYKLKAELRNDSLLQTLSPDSEHVTLKRIYGKYLRAESFRKALIYQK
KYLLLLLGGFQECEDATLALLARMGGQPAFTDLEVITNRPKGFTRFRSAVRVSIAISRMKFLVRRWHRVTGSVSININRDGFGLNQGAEK
TDSFYHSSGGLELYGEPRHTTYRSRSDLDYIRSPLPFQNRYPGTPADFNPGSLACSQLQNYDPDRALTDYITRLEALQRRLGTIQSGSTT

--------------------------------------------------------------
>In-frame_ENST00000407977_ENST00000356239_TCGA-HU-A4H5_RNF43_chr17_56492686_-_AKAP9_chr7_91674321_length(transcript)=8049nt_BP=973nt
ATATGCTGTTTGGAGAAAAAAAGAACTTTTGTTAGCAAGGAGGTTTCAGAAATGATTTTGGATTTTCTGTAAGTGTTTAATTTAGTTCTA
GGGGACAGCATCTCTCATCCCGGAGTAAATTTCTGCCTTTGACCTGCATGGATTATTTTTTCAGGCTGCGGAATTTCTCGGCACCTACCT
GTAGTATGGGGCACTTGGTTTGGTTGCAGAGTAAGAAGGTGGAAGAATGAGCTGTACTTGGTTAAGCAGTTGAAACCTTTTTTGAGCAGG
ATCTGTAAAAGCATAATTGAATTTGTTTCACCCCCGTGGATTCCAGTGGGCCCGACAGCGCAACAGTGCCTGGCAACTTGATGCATATGG
AAGAGCAATGCCAAGTGATCTGACATAATACAAATTCACGAAGTGACATTCAATCACAAGCAAAGTTGGAAATTCCAAAGAGAAGTGGTG
AGATCTTTACTAGTCACAGTGAAGATGGGAGAAAATGACATACCTGCAGCAGATGTGGGCTGAAAATATCCTCTTCTCTGCCCAATCAGG
AATGCTACCTGTTTTTGGGAATAAACTTTAGAGAAAGGAAGGGCCAAAACTACGACTTGGCTTTCTGAAACGGAAGCATAAATGTTCTTT
TCCTCCATTTGTCTGGATCTGAGAACCTGCATTTGGTATTAGCTAGTGGAAGCAGTATGTATGGTTGAAGTGCATTGCTGCAGCTGGTAG
CATGAGTGGTGGCCACCAGCTGCAGCTGGCTGCCCTCTGGCCCTGGCTGCTGATGGCTACCCTGCAGGCAGGCTTTGGACGCACAGGACT
GGTACTGGCAGCAGCGGTGGAGTCTGAAAGATCAGCAGAACAGAAAGCTATTATCAGAGTGATCCCCTTGAAAATGGACCCCACAGGAAA
ACTGAATCTCACTTTGGAAGGTGTGTTTGCTGGTGTTGCTGAAATAACTCCAGCAGAAGGAAAATTAATGCAGGTATGCACTCCAGAAAG
CTAATAATAGACTTTTGAAGATCCTCTTAGAAGTTGTAAAGACAACAGCAGCTGTTGAAGAAACAATTGGTCGCCATGTCCTTGGGATTC
TAGATAGATCTAGTAAAAGCCAGTCATCTGCCAGCCTAATTTGGAGGTCAGAAGCAGAGGCATCTGTAAAGTCATGTGTCCATGAGGAAC
ATACAAGAGTTACAGATGAATCCATTCCCTCTTATTCTGGAAGTGATATGCCAAGAAATGACATTAACATGTGGTCAAAAGTAACTGAGG
AAGGAACAGAGCTGTCACAACGACTTGTGAGGAGTGGTTTTGCTGGAACTGAAATAGACCCTGAAAATGAAGAACTTATGCTGAACATTA
GCTCTCGACTACAAGCAGCAGTTGAAAAACTCCTAGAAGCCATAAGTGAAACTAGCAGTCAGCTTGAACATGCGAAAGTGACACAGACAG
AGTTGATGCGTGAGTCATTTAGACAGAAACAAGAAGCAACAGAGTCCCTTAAGTGCCAAGAGGAACTTCGAGAGCGCCTTCATGAGGAGT
CCAGGGCCAGAGAACAGCTAGCTGTGGAGCTCAGTAAGGCTGAGGGCGTCATTGATGGCTATGCAGATGAAAAAACTCTTTTTGAAAGGC
AAATTCAGGAAAAAACTGATATAATAGATCGTCTTGAGCAGGAGTTGTTATGTGCAAGTAACAGGTTGCAAGAATTGGAGGCAGAGCAAC
AGCAGATCCAAGAAGAAAGAGAATTACTGTCCAGACAAAAGGAAGCTATGAAAGCAGAGGCAGGCCCAGTTGAACAACAATTACTACAGG
AGACAGAAAAATTAATGAAGGAAAAACTAGAAGTACAATGTCAAGCTGAAAAAGTACGTGATGACCTTCAAAAACAAGTGAAAGCTCTAG
AAATAGATGTGGAAGAACAAGTCAGTAGGTTTATAGAGCTGGAACAAGAAAAAAATACTGAACTAATGGATTTAAGACAGCAAAACCAAG
CATTGGAAAAGCAGTTAGAAAAAATGAGAAAATTTTTAGATGAGCAAGCCATTGACAGAGAACATGAGAGAGATGTATTCCAACAGGAAA
TACAGAAACTAGAACAGCAACTTAAGGTTGTTCCTCGATTCCAGCCTATCAGTGAACATCAAACTAGAGAGGTTGAACAGTTAGCAAATC
ATCTGAAAGAAAAAACAGACAAATGCAGTGAGCTTTTGCTCTCTAAAGAGCAGCTTCAAAGGGATATACAAGAAAGGAATGAAGAAATAG
AGAAACTGGAGTTCAGAGTAAGAGAACTGGAGCAGGCGCTTCTTGTGAGTGCAGATACTTTTCAAAAGGTAGAGGACCGAAAACACTTTG
GAGCTGTAGAAGCTAAACCAGAATTGTCCCTAGAAGTACAATTGCAGGCTGAACGAGATGCCATAGACAGAAAGGAAAAAGAGATTACAA
ACTTAGAAGAGCAATTAGAACAGTTTAGAGAAGAACTGGAAAATAAGAATGAAGAAGTTCAACAATTACATATGCAATTAGAAATACAGA
AAAAGGAATCTACTACCCGCCTACAAGAACTTGAACAGGAAAACAAATTATTTAAGGATGACATGGAGAAACTGGGACTTGCCATAAAGG
AATCTGATGCCATGTCTACTCAAGACCAACATGTGCTATTTGGGAAATTTGCTCAAATAATACAGGAAAAAGAGGTAGAAATTGACCAAT
TAAATGAACAAGTTACGAAACTCCAGCAGCAACTTAAAATTACAACAGATAACAAGGTTATTGAAGAAAAAAATGAACTGATAAGGGATC
TTGAAACCCAAATAGAATGTTTGATGAGTGATCAAGAATGTGTGAAGAGAAATAGAGAAGAAGAAATAGAGCAGCTCAATGAAGTGATTG
AAAAACTTCAACAGGAATTGGCAAATATTGGACAGAAGACATCAATGAATGCTCATTCCCTCTCAGAAGAAGCAGACAGTTTAAAACATC
AATTGGATGTGGTTATAGCTGAAAAGCTGGCCTTGGAACAGCAAGTAGAAACCGCTAATGAAGAAATGACCTTCATGAAAAATGTACTTA
AAGAAACCAATTTTAAAATGAATCAGCTAACACAGGAATTATTCAGCTTAAAGAGAGAACGTGAAAGTGTGGAAAAGATTCAAAGCATAC
CAGAGAATAGTGTTAACGTGGCTATAGATCATCTGAGCAAAGACAAACCTGAACTAGAAGTAGTCCTTACAGAGGATGCTCTTAAATCCC
TAGAAAATCAGACATACTTCAAATCTTTTGAAGAAAATGGCAAAGGTTCCATAATTAATTTGGAAACAAGGTTGCTACAACTTGAGAGCA
CTGTTAGTGCAAAGGACTTAGAACTTACCCAGTGTTATAAACAAATAAAAGACATGCAAGAACAAGGCCAGTTTGAAACAGAAATGCTTC
AAAAGAAGATTGTAAACCTACAGAAAATAGTTGAAGAAAAAGTGGCTGCTGCTCTTGTCAGTCAAATCCAACTTGAGGCAGTTCAGGAAT
ATGCAAAATTCTGTCAAGATAATCAAACAATTTCATCAGAACCTGAAAGAACAAATATTCAGAATTTAAATCAACTAAGAGAAGATGAGT
TGGGGTCAGATATATCAGCATTAACCTTGAGAATATCAGAATTAGAAAGCCAGGTTGTTGAAATGCATACTAGTTTGATTTTAGAAAAAG
AACAAGTAGAAATTGCAGAAAAAAATGTTTTAGAAAAAGAAAAGAAGCTGCTAGAACTACAGAAGCTATTGGAGGGCAATGAGAAAAAAC
AGAGAGAGAAAGAAAAGAAAAGAAGCCCTCAAGATGTTGAAGTTCTCAAGACAACTACTGAGCTATTTCATAGCAATGAAGAAAGTGGAT
TTTTTAATGAACTCGAGGCTCTTAGAGCTGAATCAGTGGCTACCAAAGCAGAACTTGCCAGTTATAAAGAAAAGGCTGAAAAACTTCAAG
AAGAGCTTTTGGTAAAAGAAACAAATATGACATCTCTTCAGAAAGACTTAAGCCAAGTTAGGGATCACCTCGCAGAGGCAAAAGAGAAAT
TGTCCATTTTAGAAAAAGAAGATGAGACTGAGGTACAAGAAAGCAAAAAGGCCTGCATGTTTGAGCCACTTCCTATAAAACTGAGTAAGA
GCATTGCATCCCAGACAGATGGGACTCTGAAGATCAGTAGCAGCAATCAGACTCCACAAATTCTTGTTAAAAATGCAGGAATACAAATTA
ATTTACAGAGTGAATGTTCCTCAGAAGAAGTTACTGAAATAATCAGTCAGTTTACTGAAAAAATTGAGAAGATGCAAGAACTACATGCTG
CTGAAATTTTGGACATGGAATCCAGACATATTTCAGAAACTGAAACCTTAAAGAGGGAACACTATGTTGCCGTTCAGTTACTGAAAGAGG
AATGTGGTACCTTGAAGGCAGTGATACAGTGTCTGAGAAGTAAAGAGGGATCCTCAATTCCTGAGCTAGCACATTCTGATGCTTACCAGA
CTAGAGAAATATGCTCCAGTGATTCTGGATCAGACTGGGGTCAGGGAATTTATCTTACACACAGTCAGGGATTTGACATAGCATCAGAAG
GCCGAGGAGAAGAAAGTGAAAGTGCAACAGATTCCTTTCCAAAGAAAATAAAGGGATTACTGAGAGCTGTCCATAATGAAGGCATGCAGG
TGCTTTCTCTCACTGAGTCTCCCTATAGTGATGGAGAGGACCATTCTATTCAGCAGGTTTCAGAACCTTGGCTAGAAGAGAGAAAAGCTT
ACATCAATACAATCTCATCTCTAAAGGATTTAATTACAAAGATGCAACTGCAAAGAGAAGCCGAGGTTTATGATAGTTCTCAATCTCATG
AGAGCTTCTCAGACTGGCGAGGTGAACTACTGCTTGCCCTTCAACAAGTTTTCTTAGAAGAGCGTAGTGTTTTACTAGCAGCATTTCGGA
CGGAGCTGACAGCTCTAGGTACTACAGATGCAGTTGGTTTACTAAACTGTTTGGAACAGAGAATACAAGAACAGGGTGTTGAATATCAAG
CAGCTATGGAATGCCTCCAGAAAGCAGATAGAAGGAGTTTGTTATCTGAAATTCAGGCACTGCATGCACAAATGAATGGTAGGAAAATTA
CTCTGAAAAGAGAACAAGAGAGTGAGAAACCAAGCCAAGAACTCTTGGAATATAATATACAGCAGAAGCAGTCTCAAATGCTGGAGATGC
AAGTGGAGCTCAGCAGTATGAAAGACAGAGCAACGGAACTGCAGGAGCAGCTGAGTTCTGAGAAAATGGTGGTTGCTGAACTGAAGAGTG
AGCTTGCACAAACTAAATTGGAACTAGAAACAACACTCAAGGCACAGCATAAACACCTAAAAGAATTGGAGGCTTTCAGGTTGGAAGTTA
AAGATAAGACAGATGAAGTACATTTGCTTAATGACACATTAGCAAGTGAACAGAAAAAATCAAGAGAGCTCCAGTGGGCTTTGGAGAAAG
AGAAAGCCAAGTTGGGACGCAGTGAAGAACGGGATAAAGAAGAACTTGAGGATCTGAAGTTTTCACTTGAGAGTCAGAAACAAAGGAATC
TTCAGCTAAATCTACTTTTGGAACAACAGAAACAACTACTGAACGAATCCCAGCAAAAAATAGAATCACAGAGAATGCTATATGATGCCC
AGTTGTCAGAAGAACAAGGTCGAAACTTAGAGCTTCAGGTACTTCTTGAATCTGAGAAAGTTCGAATTCGGGAAATGAGTAGTACCCTAG
ATAGGGAGCGGGAATTGCACGCACAGCTGCAGAGCAGTGATGGTACTGGACAGTCTCGGCCACCCTTGCCCTCAGAGGACCTACTGAAAG
AGCTGCAGAAACAGCTAGAGGAAAAACACAGTCGCATAGTAGAATTGTTAAATGAGACTGAAAAATATAAACTGGATTCTTTGCAAACAC
GACAGCAAATGGAAAAAGATAGGCAGGTTCACAGGAAAACACTGCAGACAGAACAGGAGGCCAACACTGAGGGACAGAAAAAAATGCATG
AGCTCCAGTCCAAAGTGGAAGATCTTCAGCGCCAGCTGGAAGAGAAAAGACAACAAGTTTATAAGTTAGACCTTGAAGGACAGCGACTAC
AAGGAATCATGCAGGAATTCCAGAAGCAAGAACTAGAACGAGAAGAAAAACGAGAAAGTAGAAGAATTCTGTATCAGAACCTTAATGAGC
CAACCACGTGGAGCTTAACCAGTGATAGAACTAGAAATTGGGTTCTTCAACAGAAAATAGAAGGAGAAACAAAAGAATCAAACTACGCTA
AATTGATTGAAATGAATGGAGGAGGAACCGGCTGTAATCATGAATTAGAAATGATCAGACAAAAGCTTCAATGTGTAGCTTCAAAACTAC
AGGTTCTACCCCAGAAAGCCTCTGAGAGACTACAGTTTGAAACAGCAGATGATGAAGATTTCATTTGGGTTCAGGAAAATATTGATGAAA
TTATTTTACAACTACAGAAATTAACTGGCCAGCAAGGTGAAGAGCCCAGCTTGGTGTCCCCAAGTACTTCTTGTGGCTCATTGACTGAAA
GACTACTGAGACAAAATGCTGAGCTGACAGGGCATATCAGTCAACTGACTGAAGAGAAGAATGACTTAAGGAACATGGTTATGAAGCTGG
AAGAGCAGATCAGGTGGTATCGACAGACAGGAGCTGGTAGAGATAATTCTTCCAGGTTTTCATTGAATGGTGGTGCCAACATTGAAGCCA
TCATTGCCTCTGAAAAAGAAGTATGGAACAGAGAAAAATTGACTCTCCAGAAATCTTTGAAAAGGGCAGAGGCTGAAGTATACAAACTGA
AAGCTGAACTAAGAAATGACTCTTTACTTCAAACTCTGAGCCCTGATTCTGAACATGTCACTTTAAAGAGAATTTATGGTAAATACTTGA
GGGCAGAAAGTTTTCGAAAGGCTCTCATTTACCAGAAGAAATACCTGCTGCTGTTACTGGGTGGGTTCCAGGAATGTGAAGATGCCACCT
TGGCCCTGCTTGCCCGGATGGGGGGGCAGCCAGCTTTCACGGATCTAGAGGTGATCACCAATCGCCCAAAGGGCTTCACCAGGTTTCGGT
CGGCCGTCAGAGTATCCATTGCAATTTCCAGAATGAAATTTTTGGTTCGACGGTGGCATCGAGTCACAGGTTCTGTTTCCATCAATATTA
ACAGAGATGGCTTTGGACTGAATCAAGGTGCAGAAAAGACTGACTCATTTTATCATTCTTCTGGTGGGCTGGAGTTATATGGAGAACCAA
GACATACTACGTATCGCTCAAGATCAGATCTGGACTATATTAGGTCCCCTTTACCATTTCAGAATAGGTACCCAGGCACTCCAGCTGATT
TCAATCCTGGTTCTTTAGCATGTTCTCAGCTTCAGAATTACGATCCTGACAGAGCCCTAACAGATTATATCACTCGGCTAGAGGCACTGC
AAAGACGACTTGGAACTATACAGTCAGGTTCAACTACTCAATTTCATGCTGGCATGAGAAGATAATCCTTTGAAACATCATTAATTGAAG
TGATTTTAAATAGATTTCCTTTTGTAAATCAATGGTTCTTTTGTGCTTTTGTATTGTGAATATTCAATGGGACCAATATGAACACAGCTT
ATGATTGTATACAAATCCCTTGCCAGCACATGAAAACAAACTGGAATTTGTATATATAAGCATTGTGTATGTATTCATGCACAATAATTA
TTGAATTACCTGTATATTTGTGGAATGCTAATTTAAAACATTAAATTATAAACCTTGTGTATTTATCAAATGGGTGAAAAGATTAAACTT
TTACGCATTACAATACTGCTGAATGTGTAGCTCGAGGTGTCCTGCACTTTTCTTATAAGGCTACTGAAGTTACATGTTTTGCCTAATATA
TTCTACTGGTGATGAAGACAGATAATATCACTTGTAGAGACCTATTTTTGTATAATGGTAGAAGTTTTGAATTTTATGGGGTATTTTGTC

>In-frame_ENST00000407977_ENST00000356239_TCGA-HU-A4H5_RNF43_chr17_56492686_-_AKAP9_chr7_91674321_length(amino acids)=2176AA_start in transcript=1004_stop in transcript=7534
MKILLEVVKTTAAVEETIGRHVLGILDRSSKSQSSASLIWRSEAEASVKSCVHEEHTRVTDESIPSYSGSDMPRNDINMWSKVTEEGTEL
SQRLVRSGFAGTEIDPENEELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEELRERLHEESRARE
QLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKL
MKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLE
QQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEA
KPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAM
STQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQ
ELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSV
NVAIDHLSKDKPELEVVLTEDALKSLENQTYFKSFEENGKGSIINLETRLLQLESTVSAKDLELTQCYKQIKDMQEQGQFETEMLQKKIV
NLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLREDELGSDISALTLRISELESQVVEMHTSLILEKEQVEI
AEKNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQEELLV
KETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQESKKACMFEPLPIKLSKSIASQTDGTLKISSSNQTPQILVKNAGIQINLQSE
CSSEEVTEIISQFTEKIEKMQELHAAEILDMESRHISETETLKREHYVAVQLLKEECGTLKAVIQCLRSKEGSSIPELAHSDAYQTREIC
SSDSGSDWGQGIYLTHSQGFDIASEGRGEESESATDSFPKKIKGLLRAVHNEGMQVLSLTESPYSDGEDHSIQQVSEPWLEERKAYINTI
SSLKDLITKMQLQREAEVYDSSQSHESFSDWRGELLLALQQVFLEERSVLLAAFRTELTALGTTDAVGLLNCLEQRIQEQGVEYQAAMEC
LQKADRRSLLSEIQALHAQMNGRKITLKREQESEKPSQELLEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQT
KLELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNL
LLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKELQKQ
LEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQGIMQ
EFQKQELEREEKRESRRILYQNLNEPTTWSLTSDRTRNWVLQQKIEGETKESNYAKLIEMNGGGTGCNHELEMIRQKLQCVASKLQVLPQ
KASERLQFETADDEDFIWVQENIDEIILQLQKLTGQQGEEPSLVSPSTSCGSLTERLLRQNAELTGHISQLTEEKNDLRNMVMKLEEQIR
WYRQTGAGRDNSSRFSLNGGANIEAIIASEKEVWNREKLTLQKSLKRAEAEVYKLKAELRNDSLLQTLSPDSEHVTLKRIYGKYLRAESF
RKALIYQKKYLLLLLGGFQECEDATLALLARMGGQPAFTDLEVITNRPKGFTRFRSAVRVSIAISRMKFLVRRWHRVTGSVSININRDGF
GLNQGAEKTDSFYHSSGGLELYGEPRHTTYRSRSDLDYIRSPLPFQNRYPGTPADFNPGSLACSQLQNYDPDRALTDYITRLEALQRRLG

--------------------------------------------------------------
>In-frame_ENST00000407977_ENST00000358100_TCGA-HU-A4H5_RNF43_chr17_56492686_-_AKAP9_chr7_91674321_length(transcript)=7863nt_BP=973nt
ATATGCTGTTTGGAGAAAAAAAGAACTTTTGTTAGCAAGGAGGTTTCAGAAATGATTTTGGATTTTCTGTAAGTGTTTAATTTAGTTCTA
GGGGACAGCATCTCTCATCCCGGAGTAAATTTCTGCCTTTGACCTGCATGGATTATTTTTTCAGGCTGCGGAATTTCTCGGCACCTACCT
GTAGTATGGGGCACTTGGTTTGGTTGCAGAGTAAGAAGGTGGAAGAATGAGCTGTACTTGGTTAAGCAGTTGAAACCTTTTTTGAGCAGG
ATCTGTAAAAGCATAATTGAATTTGTTTCACCCCCGTGGATTCCAGTGGGCCCGACAGCGCAACAGTGCCTGGCAACTTGATGCATATGG
AAGAGCAATGCCAAGTGATCTGACATAATACAAATTCACGAAGTGACATTCAATCACAAGCAAAGTTGGAAATTCCAAAGAGAAGTGGTG
AGATCTTTACTAGTCACAGTGAAGATGGGAGAAAATGACATACCTGCAGCAGATGTGGGCTGAAAATATCCTCTTCTCTGCCCAATCAGG
AATGCTACCTGTTTTTGGGAATAAACTTTAGAGAAAGGAAGGGCCAAAACTACGACTTGGCTTTCTGAAACGGAAGCATAAATGTTCTTT
TCCTCCATTTGTCTGGATCTGAGAACCTGCATTTGGTATTAGCTAGTGGAAGCAGTATGTATGGTTGAAGTGCATTGCTGCAGCTGGTAG
CATGAGTGGTGGCCACCAGCTGCAGCTGGCTGCCCTCTGGCCCTGGCTGCTGATGGCTACCCTGCAGGCAGGCTTTGGACGCACAGGACT
GGTACTGGCAGCAGCGGTGGAGTCTGAAAGATCAGCAGAACAGAAAGCTATTATCAGAGTGATCCCCTTGAAAATGGACCCCACAGGAAA
ACTGAATCTCACTTTGGAAGGTGTGTTTGCTGGTGTTGCTGAAATAACTCCAGCAGAAGGAAAATTAATGCAGGTATGCACTCCAGAAAG
CTAATAATAGACTTTTGAAGATCCTCTTAGAAGTTGTAAAGACAACAGCAGCTGTTGAAGAAACAATTGGTCGCCATGTCCTTGGGATTC
TAGATAGATCTAGTAAAAGCCAGTCATCTGCCAGCCTAATTTGGAGGTCAGAAGCAGAGGCATCTGTAAAGTCATGTGTCCATGAGGAAC
ATACAAGAGTTACAGATGAATCCATTCCCTCTTATTCTGGAAGTGATATGCCAAGAAATGACATTAACATGTGGTCAAAAGTAACTGAGG
AAGGAACAGAGCTGTCACAACGACTTGTGAGGAGTGGTTTTGCTGGAACTGAAATAGACCCTGAAAATGAAGAACTTATGCTGAACATTA
GCTCTCGACTACAAGCAGCAGTTGAAAAACTCCTAGAAGCCATAAGTGAAACTAGCAGTCAGCTTGAACATGCGAAAGTGACACAGACAG
AGTTGATGCGTGAGTCATTTAGACAGAAACAAGAAGCAACAGAGTCCCTTAAGTGCCAAGAGGAACTTCGAGAGCGCCTTCATGAGGAGT
CCAGGGCCAGAGAACAGCTAGCTGTGGAGCTCAGTAAGGCTGAGGGCGTCATTGATGGCTATGCAGATGAAAAAACTCTTTTTGAAAGGC
AAATTCAGGAAAAAACTGATATAATAGATCGTCTTGAGCAGGAGTTGTTATGTGCAAGTAACAGGTTGCAAGAATTGGAGGCAGAGCAAC
AGCAGATCCAAGAAGAAAGAGAATTACTGTCCAGACAAAAGGAAGCTATGAAAGCAGAGGCAGGCCCAGTTGAACAACAATTACTACAGG
AGACAGAAAAATTAATGAAGGAAAAACTAGAAGTACAATGTCAAGCTGAAAAAGTACGTGATGACCTTCAAAAACAAGTGAAAGCTCTAG
AAATAGATGTGGAAGAACAAGTCAGTAGGTTTATAGAGCTGGAACAAGAAAAAAATACTGAACTAATGGATTTAAGACAGCAAAACCAAG
CATTGGAAAAGCAGTTAGAAAAAATGAGAAAATTTTTAGATGAGCAAGCCATTGACAGAGAACATGAGAGAGATGTATTCCAACAGGAAA
TACAGAAACTAGAACAGCAACTTAAGGTTGTTCCTCGATTCCAGCCTATCAGTGAACATCAAACTAGAGAGGTTGAACAGTTAGCAAATC
ATCTGAAAGAAAAAACAGACAAATGCAGTGAGCTTTTGCTCTCTAAAGAGCAGCTTCAAAGGGATATACAAGAAAGGAATGAAGAAATAG
AGAAACTGGAGTTCAGAGTAAGAGAACTGGAGCAGGCGCTTCTTGTGAGTGCAGATACTTTTCAAAAGGTAGAGGACCGAAAACACTTTG
GAGCTGTAGAAGCTAAACCAGAATTGTCCCTAGAAGTACAATTGCAGGCTGAACGAGATGCCATAGACAGAAAGGAAAAAGAGATTACAA
ACTTAGAAGAGCAATTAGAACAGTTTAGAGAAGAACTGGAAAATAAGAATGAAGAAGTTCAACAATTACATATGCAATTAGAAATACAGA
AAAAGGAATCTACTACCCGCCTACAAGAACTTGAACAGGAAAACAAATTATTTAAGGATGACATGGAGAAACTGGGACTTGCCATAAAGG
AATCTGATGCCATGTCTACTCAAGACCAACATGTGCTATTTGGGAAATTTGCTCAAATAATACAGGAAAAAGAGGTAGAAATTGACCAAT
TAAATGAACAAGTTACGAAACTCCAGCAGCAACTTAAAATTACAACAGATAACAAGGTTATTGAAGAAAAAAATGAACTGATAAGGGATC
TTGAAACCCAAATAGAATGTTTGATGAGTGATCAAGAATGTGTGAAGAGAAATAGAGAAGAAGAAATAGAGCAGCTCAATGAAGTGATTG
AAAAACTTCAACAGGAATTGGCAAATATTGGACAGAAGACATCAATGAATGCTCATTCCCTCTCAGAAGAAGCAGACAGTTTAAAACATC
AATTGGATGTGGTTATAGCTGAAAAGCTGGCCTTGGAACAGCAAGTAGAAACCGCTAATGAAGAAATGACCTTCATGAAAAATGTACTTA
AAGAAACCAATTTTAAAATGAATCAGCTAACACAGGAATTATTCAGCTTAAAGAGAGAACGTGAAAGTGTGGAAAAGATTCAAAGCATAC
CAGAGAATAGTGTTAACGTGGCTATAGATCATCTGAGCAAAGACAAACCTGAACTAGAAGTAGTCCTTACAGAGGATGCTCTTAAATCCC
TAGAAAATCAGACATACTTCAAATCTTTTGAAGAAAATGGCAAAGGTTCCATAATTAATTTGGAAACAAGGTTGCTACAACTTGAGAGCA
CTGTTAGTGCAAAGGACTTAGAACTTACCCAGTGTTATAAACAAATAAAAGACATGCAAGAACAAGGCCAGTTTGAAACAGAAATGCTTC
AAAAGAAGATTGTAAACCTACAGAAAATAGTTGAAGAAAAAGTGGCTGCTGCTCTTGTCAGTCAAATCCAACTTGAGGCAGTTCAGGAAT
ATGCAAAATTCTGTCAAGATAATCAAACAATTTCATCAGAACCTGAAAGAACAAATATTCAGAATTTAAATCAACTAAGAGAAGATGAGT
TGGGGTCAGATATATCAGCATTAACCTTGAGAATATCAGAATTAGAAAGCCAGGTTGTTGAAATGCATACTAGTTTGATTTTAGAAAAAG
AACAAGTAGAAATTGCAGAAAAAAATGTTTTAGAAAAAGAAAAGAAGCTGCTAGAACTACAGAAGCTATTGGAGGGCAATGAGAAAAAAC
AGAGAGAGAAAGAAAAGAAAAGAAGCCCTCAAGATGTTGAAGTTCTCAAGACAACTACTGAGCTATTTCATAGCAATGAAGAAAGTGGAT
TTTTTAATGAACTCGAGGCTCTTAGAGCTGAATCAGTGGCTACCAAAGCAGAACTTGCCAGTTATAAAGAAAAGGCTGAAAAACTTCAAG
AAGAGCTTTTGGTAAAAGAAACAAATATGACATCTCTTCAGAAAGACTTAAGCCAAGTTAGGGATCACCTCGCAGAGGCAAAAGAGAAAT
TGTCCATTTTAGAAAAAGAAGATGAGACTGAGGTACAAGAAAGCAAAAAGGCCTGCATGTTTGAGCCACTTCCTATAAAACTGAGTAAGA
GCATTGCATCCCAGACAGATGGGACTCTGAAGATCAGTAGCAGCAATCAGACTCCACAAATTCTTGTTAAAAATGCAGGAATACAAATTA
ATTTACAGAGTGAATGTTCCTCAGAAGAAGTTACTGAAATAATCAGTCAGTTTACTGAAAAAATTGAGAAGATGCAAGAACTACATGCTG
CTGAAATTTTGGACATGGAATCCAGACATATTTCAGAAACTGAAACCTTAAAGAGGGAACACTATGTTGCCGTTCAGTTACTGAAAGAGG
AATGTGGTACCTTGAAGGCAGTGATACAGTGTCTGAGAAGTAAAGAGGGATTACTGAGAGCTGTCCATAATGAAGGCATGCAGGTGCTTT
CTCTCACTGAGTCTCCCTATAGTGATGGAGAGGACCATTCTATTCAGCAGGTTTCAGAACCTTGGCTAGAAGAGAGAAAAGCTTACATCA
ATACAATCTCATCTCTAAAGGATTTAATTACAAAGATGCAACTGCAAAGAGAAGCCGAGGTTTATGATAGTTCTCAATCTCATGAGAGCT
TCTCAGACTGGCGAGGTGAACTACTGCTTGCCCTTCAACAAGTTTTCTTAGAAGAGCGTAGTGTTTTACTAGCAGCATTTCGGACGGAGC
TGACAGCTCTAGGTACTACAGATGCAGTTGGTTTACTAAACTGTTTGGAACAGAGAATACAAGAACAGGGTGTTGAATATCAAGCAGCTA
TGGAATGCCTCCAGAAAGCAGATAGAAGGAGTTTGTTATCTGAAATTCAGGCACTGCATGCACAAATGAATGGTAGGAAAATTACTCTGA
AAAGAGAACAAGAGAGTGAGAAACCAAGCCAAGAACTCTTGGAATATAATATACAGCAGAAGCAGTCTCAAATGCTGGAGATGCAAGTGG
AGCTCAGCAGTATGAAAGACAGAGCAACGGAACTGCAGGAGCAGCTGAGTTCTGAGAAAATGGTGGTTGCTGAACTGAAGAGTGAGCTTG
CACAAACTAAATTGGAACTAGAAACAACACTCAAGGCACAGCATAAACACCTAAAAGAATTGGAGGCTTTCAGGTTGGAAGTTAAAGATA
AGACAGATGAAGTACATTTGCTTAATGACACATTAGCAAGTGAACAGAAAAAATCAAGAGAGCTCCAGTGGGCTTTGGAGAAAGAGAAAG
CCAAGTTGGGACGCAGTGAAGAACGGGATAAAGAAGAACTTGAGGATCTGAAGTTTTCACTTGAGAGTCAGAAACAAAGGAATCTTCAGC
TAAATCTACTTTTGGAACAACAGAAACAACTACTGAACGAATCCCAGCAAAAAATAGAATCACAGAGAATGCTATATGATGCCCAGTTGT
CAGAAGAACAAGGTCGAAACTTAGAGCTTCAGGTACTTCTTGAATCTGAGAAAGTTCGAATTCGGGAAATGAGTAGTACCCTAGATAGGG
AGCGGGAATTGCACGCACAGCTGCAGAGCAGTGATGGTACTGGACAGTCTCGGCCACCCTTGCCCTCAGAGGACCTACTGAAAGAGCTGC
AGAAACAGCTAGAGGAAAAACACAGTCGCATAGTAGAATTGTTAAATGAGACTGAAAAATATAAACTGGATTCTTTGCAAACACGACAGC
AAATGGAAAAAGATAGGCAGGTTCACAGGAAAACACTGCAGACAGAACAGGAGGCCAACACTGAGGGACAGAAAAAAATGCATGAGCTCC
AGTCCAAAGTGGAAGATCTTCAGCGCCAGCTGGAAGAGAAAAGACAACAAGTTTATAAGTTAGACCTTGAAGGACAGCGACTACAAGGAA
TCATGCAGGAATTCCAGAAGCAAGAACTAGAACGAGAAGAAAAACGAGAAAGTAGAAGAATTCTGTATCAGAACCTTAATGAGCCAACCA
CGTGGAGCTTAACCAGTGATAGAACTAGAAATTGGGTTCTTCAACAGAAAATAGAAGGAGAAACAAAAGAATCAAACTACGCTAAATTGA
TTGAAATGAATGGAGGAGGAACCGGCTGTAATCATGAATTAGAAATGATCAGACAAAAGCTTCAATGTGTAGCTTCAAAACTACAGGTTC
TACCCCAGAAAGCCTCTGAGAGACTACAGTTTGAAACAGCAGATGATGAAGATTTCATTTGGGTTCAGGAAAATATTGATGAAATTATTT
TACAACTACAGAAATTAACTGGCCAGCAAGGTGAAGAGCCCAGCTTGGTGTCCCCAAGTACTTCTTGTGGCTCATTGACTGAAAGACTAC
TGAGACAAAATGCTGAGCTGACAGGGCATATCAGTCAACTGACTGAAGAGAAGAATGACTTAAGGAACATGGTTATGAAGCTGGAAGAGC
AGATCAGGTGGTATCGACAGACAGGAGCTGGTAGAGATAATTCTTCCAGGTTTTCATTGAATGGTGGTGCCAACATTGAAGCCATCATTG
CCTCTGAAAAAGAAGTATGGAACAGAGAAAAATTGACTCTCCAGAAATCTTTGAAAAGGGCAGAGGCTGAAGTATACAAACTGAAAGCTG
AACTAAGAAATGACTCTTTACTTCAAACTCTGAGCCCTGATTCTGAACATGTCACTTTAAAGAGAATTTATGGTAAATACTTGAGGGCAG
AAAGTTTTCGAAAGGCTCTCATTTACCAGAAGAAATACCTGCTGCTGTTACTGGGTGGGTTCCAGGAATGTGAAGATGCCACCTTGGCCC
TGCTTGCCCGGATGGGGGGGCAGCCAGCTTTCACGGATCTAGAGGTGATCACCAATCGCCCAAAGGGCTTCACCAGGTTTCGGTCGGCCG
TCAGAGTATCCATTGCAATTTCCAGAATGAAATTTTTGGTTCGACGGTGGCATCGAGTCACAGGTTCTGTTTCCATCAATATTAACAGAG
ATGGCTTTGGACTGAATCAAGGTGCAGAAAAGACTGACTCATTTTATCATTCTTCTGGTGGGCTGGAGTTATATGGAGAACCAAGACATA
CTACGTATCGCTCAAGATCAGATCTGGACTATATTAGGTCCCCTTTACCATTTCAGAATAGGTACCCAGGCACTCCAGCTGATTTCAATC
CTGGTTCTTTAGCATGTTCTCAGCTTCAGAATTACGATCCTGACAGAGCCCTAACAGATTATATCACTCGGCTAGAGGCACTGCAAAGAC
GACTTGGAACTATACAGTCAGGTTCAACTACTCAATTTCATGCTGGCATGAGAAGATAATCCTTTGAAACATCATTAATTGAAGTGATTT
TAAATAGATTTCCTTTTGTAAATCAATGGTTCTTTTGTGCTTTTGTATTGTGAATATTCAATGGGACCAATATGAACACAGCTTATGATT
GTATACAAATCCCTTGCCAGCACATGAAAACAAACTGGAATTTGTATATATAAGCATTGTGTATGTATTCATGCACAATAATTATTGAAT
TACCTGTATATTTGTGGAATGCTAATTTAAAACATTAAATTATAAACCTTGTGTATTTATCAAATGGGTGAAAAGATTAAACTTTTACGC
ATTACAATACTGCTGAATGTGTAGCTCGAGGTGTCCTGCACTTTTCTTATAAGGCTACTGAAGTTACATGTTTTGCCTAATATATTCTAC
TGGTGATGAAGACAGATAATATCACTTGTAGAGACCTATTTTTGTATAATGGTAGAAGTTTTGAATTTTATGGGGTATTTTGTCAAGTAC

>In-frame_ENST00000407977_ENST00000358100_TCGA-HU-A4H5_RNF43_chr17_56492686_-_AKAP9_chr7_91674321_length(amino acids)=2114AA_start in transcript=1004_stop in transcript=7348
MKILLEVVKTTAAVEETIGRHVLGILDRSSKSQSSASLIWRSEAEASVKSCVHEEHTRVTDESIPSYSGSDMPRNDINMWSKVTEEGTEL
SQRLVRSGFAGTEIDPENEELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEELRERLHEESRARE
QLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKL
MKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLE
QQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEA
KPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAM
STQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQ
ELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSV
NVAIDHLSKDKPELEVVLTEDALKSLENQTYFKSFEENGKGSIINLETRLLQLESTVSAKDLELTQCYKQIKDMQEQGQFETEMLQKKIV
NLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLREDELGSDISALTLRISELESQVVEMHTSLILEKEQVEI
AEKNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQEELLV
KETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQESKKACMFEPLPIKLSKSIASQTDGTLKISSSNQTPQILVKNAGIQINLQSE
CSSEEVTEIISQFTEKIEKMQELHAAEILDMESRHISETETLKREHYVAVQLLKEECGTLKAVIQCLRSKEGLLRAVHNEGMQVLSLTES
PYSDGEDHSIQQVSEPWLEERKAYINTISSLKDLITKMQLQREAEVYDSSQSHESFSDWRGELLLALQQVFLEERSVLLAAFRTELTALG
TTDAVGLLNCLEQRIQEQGVEYQAAMECLQKADRRSLLSEIQALHAQMNGRKITLKREQESEKPSQELLEYNIQQKQSQMLEMQVELSSM
KDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGR
SEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDRERELH
AQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVE
DLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQELEREEKRESRRILYQNLNEPTTWSLTSDRTRNWVLQQKIEGETKESNYAKLIEMNG
GGTGCNHELEMIRQKLQCVASKLQVLPQKASERLQFETADDEDFIWVQENIDEIILQLQKLTGQQGEEPSLVSPSTSCGSLTERLLRQNA
ELTGHISQLTEEKNDLRNMVMKLEEQIRWYRQTGAGRDNSSRFSLNGGANIEAIIASEKEVWNREKLTLQKSLKRAEAEVYKLKAELRND
SLLQTLSPDSEHVTLKRIYGKYLRAESFRKALIYQKKYLLLLLGGFQECEDATLALLARMGGQPAFTDLEVITNRPKGFTRFRSAVRVSI
AISRMKFLVRRWHRVTGSVSININRDGFGLNQGAEKTDSFYHSSGGLELYGEPRHTTYRSRSDLDYIRSPLPFQNRYPGTPADFNPGSLA

--------------------------------------------------------------
>In-frame_ENST00000407977_ENST00000359028_TCGA-HU-A4H5_RNF43_chr17_56492686_-_AKAP9_chr7_91674321_length(transcript)=8025nt_BP=973nt
ATATGCTGTTTGGAGAAAAAAAGAACTTTTGTTAGCAAGGAGGTTTCAGAAATGATTTTGGATTTTCTGTAAGTGTTTAATTTAGTTCTA
GGGGACAGCATCTCTCATCCCGGAGTAAATTTCTGCCTTTGACCTGCATGGATTATTTTTTCAGGCTGCGGAATTTCTCGGCACCTACCT
GTAGTATGGGGCACTTGGTTTGGTTGCAGAGTAAGAAGGTGGAAGAATGAGCTGTACTTGGTTAAGCAGTTGAAACCTTTTTTGAGCAGG
ATCTGTAAAAGCATAATTGAATTTGTTTCACCCCCGTGGATTCCAGTGGGCCCGACAGCGCAACAGTGCCTGGCAACTTGATGCATATGG
AAGAGCAATGCCAAGTGATCTGACATAATACAAATTCACGAAGTGACATTCAATCACAAGCAAAGTTGGAAATTCCAAAGAGAAGTGGTG
AGATCTTTACTAGTCACAGTGAAGATGGGAGAAAATGACATACCTGCAGCAGATGTGGGCTGAAAATATCCTCTTCTCTGCCCAATCAGG
AATGCTACCTGTTTTTGGGAATAAACTTTAGAGAAAGGAAGGGCCAAAACTACGACTTGGCTTTCTGAAACGGAAGCATAAATGTTCTTT
TCCTCCATTTGTCTGGATCTGAGAACCTGCATTTGGTATTAGCTAGTGGAAGCAGTATGTATGGTTGAAGTGCATTGCTGCAGCTGGTAG
CATGAGTGGTGGCCACCAGCTGCAGCTGGCTGCCCTCTGGCCCTGGCTGCTGATGGCTACCCTGCAGGCAGGCTTTGGACGCACAGGACT
GGTACTGGCAGCAGCGGTGGAGTCTGAAAGATCAGCAGAACAGAAAGCTATTATCAGAGTGATCCCCTTGAAAATGGACCCCACAGGAAA
ACTGAATCTCACTTTGGAAGGTGTGTTTGCTGGTGTTGCTGAAATAACTCCAGCAGAAGGAAAATTAATGCAGGTATGCACTCCAGAAAG
CTAATAATAGACTTTTGAAGATCCTCTTAGAAGTTGTAAAGACAACAGCAGCTGTTGAAGAAACAATTGGTCGCCATGTCCTTGGGATTC
TAGATAGATCTAGTAAAAGCCAGTCATCTGCCAGCCTAATTTGGAGGTCAGAAGCAGAGGCATCTGTAAAGTCATGTGTCCATGAGGAAC
ATACAAGAGTTACAGATGAATCCATTCCCTCTTATTCTGGAAGTGATATGCCAAGAAATGACATTAACATGTGGTCAAAAGTAACTGAGG
AAGGAACAGAGCTGTCACAACGACTTGTGAGGAGTGGTTTTGCTGGAACTGAAATAGACCCTGAAAATGAAGAACTTATGCTGAACATTA
GCTCTCGACTACAAGCAGCAGTTGAAAAACTCCTAGAAGCCATAAGTGAAACTAGCAGTCAGCTTGAACATGCGAAAGTGACACAGACAG
AGTTGATGCGTGAGTCATTTAGACAGAAACAAGAAGCAACAGAGTCCCTTAAGTGCCAAGAGGAACTTCGAGAGCGCCTTCATGAGGAGT
CCAGGGCCAGAGAACAGCTAGCTGTGGAGCTCAGTAAGGCTGAGGGCGTCATTGATGGCTATGCAGATGAAAAAACTCTTTTTGAAAGGC
AAATTCAGGAAAAAACTGATATAATAGATCGTCTTGAGCAGGAGTTGTTATGTGCAAGTAACAGGTTGCAAGAATTGGAGGCAGAGCAAC
AGCAGATCCAAGAAGAAAGAGAATTACTGTCCAGACAAAAGGAAGCTATGAAAGCAGAGGCAGGCCCAGTTGAACAACAATTACTACAGG
AGACAGAAAAATTAATGAAGGAAAAACTAGAAGTACAATGTCAAGCTGAAAAAGTACGTGATGACCTTCAAAAACAAGTGAAAGCTCTAG
AAATAGATGTGGAAGAACAAGTCAGTAGGTTTATAGAGCTGGAACAAGAAAAAAATACTGAACTAATGGATTTAAGACAGCAAAACCAAG
CATTGGAAAAGCAGTTAGAAAAAATGAGAAAATTTTTAGATGAGCAAGCCATTGACAGAGAACATGAGAGAGATGTATTCCAACAGGAAA
TACAGAAACTAGAACAGCAACTTAAGGTTGTTCCTCGATTCCAGCCTATCAGTGAACATCAAACTAGAGAGGTTGAACAGTTAGCAAATC
ATCTGAAAGAAAAAACAGACAAATGCAGTGAGCTTTTGCTCTCTAAAGAGCAGCTTCAAAGGGATATACAAGAAAGGAATGAAGAAATAG
AGAAACTGGAGTTCAGAGTAAGAGAACTGGAGCAGGCGCTTCTTGTGAGTGCAGATACTTTTCAAAAGGTAGAGGACCGAAAACACTTTG
GAGCTGTAGAAGCTAAACCAGAATTGTCCCTAGAAGTACAATTGCAGGCTGAACGAGATGCCATAGACAGAAAGGAAAAAGAGATTACAA
ACTTAGAAGAGCAATTAGAACAGTTTAGAGAAGAACTGGAAAATAAGAATGAAGAAGTTCAACAATTACATATGCAATTAGAAATACAGA
AAAAGGAATCTACTACCCGCCTACAAGAACTTGAACAGGAAAACAAATTATTTAAGGATGACATGGAGAAACTGGGACTTGCCATAAAGG
AATCTGATGCCATGTCTACTCAAGACCAACATGTGCTATTTGGGAAATTTGCTCAAATAATACAGGAAAAAGAGGTAGAAATTGACCAAT
TAAATGAACAAGTTACGAAACTCCAGCAGCAACTTAAAATTACAACAGATAACAAGGTTATTGAAGAAAAAAATGAACTGATAAGGGATC
TTGAAACCCAAATAGAATGTTTGATGAGTGATCAAGAATGTGTGAAGAGAAATAGAGAAGAAGAAATAGAGCAGCTCAATGAAGTGATTG
AAAAACTTCAACAGGAATTGGCAAATATTGGACAGAAGACATCAATGAATGCTCATTCCCTCTCAGAAGAAGCAGACAGTTTAAAACATC
AATTGGATGTGGTTATAGCTGAAAAGCTGGCCTTGGAACAGCAAGTAGAAACCGCTAATGAAGAAATGACCTTCATGAAAAATGTACTTA
AAGAAACCAATTTTAAAATGAATCAGCTAACACAGGAATTATTCAGCTTAAAGAGAGAACGTGAAAGTGTGGAAAAGATTCAAAGCATAC
CAGAGAATAGTGTTAACGTGGCTATAGATCATCTGAGCAAAGACAAACCTGAACTAGAAGTAGTCCTTACAGAGGATGCTCTTAAATCCC
TAGAAAATCAGACATACTTCAAATCTTTTGAAGAAAATGGCAAAGGTTCCATAATTAATTTGGAAACAAGGTTGCTACAACTTGAGAGCA
CTGTTAGTGCAAAGGACTTAGAACTTACCCAGTGTTATAAACAAATAAAAGACATGCAAGAACAAGGCCAGTTTGAAACAGAAATGCTTC
AAAAGAAGATTGTAAACCTACAGAAAATAGTTGAAGAAAAAGTGGCTGCTGCTCTTGTCAGTCAAATCCAACTTGAGGCAGTTCAGGAAT
ATGCAAAATTCTGTCAAGATAATCAAACAATTTCATCAGAACCTGAAAGAACAAATATTCAGAATTTAAATCAACTAAGAGAAGATGAGT
TGGGGTCAGATATATCAGCATTAACCTTGAGAATATCAGAATTAGAAAGCCAGGTTGTTGAAATGCATACTAGTTTGATTTTAGAAAAAG
AACAAGTAGAAATTGCAGAAAAAAATGTTTTAGAAAAAGAAAAGAAGCTGCTAGAACTACAGAAGCTATTGGAGGGCAATGAGAAAAAAC
AGAGAGAGAAAGAAAAGAAAAGAAGCCCTCAAGATGTTGAAGTTCTCAAGACAACTACTGAGCTATTTCATAGCAATGAAGAAAGTGGAT
TTTTTAATGAACTCGAGGCTCTTAGAGCTGAATCAGTGGCTACCAAAGCAGAACTTGCCAGTTATAAAGAAAAGGCTGAAAAACTTCAAG
AAGAGCTTTTGGTAAAAGAAACAAATATGACATCTCTTCAGAAAGACTTAAGCCAAGTTAGGGATCACCTCGCAGAGGCAAAAGAGAAAT
TGTCCATTTTAGAAAAAGAAGATGAGACTGAGGTACAAGAAAGCAAAAAGGCCTGCATGTTTGAGCCACTTCCTATAAAACTGAGTAAGA
GCATTGCATCCCAGACAGATGGGACTCTGAAGATCAGTAGCAGCAATCAGACTCCACAAATTCTTGTTAAAAATGCAGGAATACAAATTA
ATTTACAGAGTGAATGTTCCTCAGAAGAAGTTACTGAAATAATCAGTCAGTTTACTGAAAAAATTGAGAAGATGCAAGAACTACATGCTG
CTGAAATTTTGGACATGGAATCCAGACATATTTCAGAAACTGAAACCTTAAAGAGGGAACACTATGTTGCCGTTCAGTTACTGAAAGAGG
AATGTGGTACCTTGAAGGCAGTGATACAGTGTCTGAGAAGTAAAGAGGTATTTGGTTTTTATAATATGTGTTTTTCAACATTGTGTGATT
CTGGATCAGACTGGGGTCAGGGAATTTATCTTACACACAGTCAGGGATTTGACATAGCATCAGAAGGCCGAGGAGAAGAAAGTGAAAGTG
CAACAGATTCCTTTCCAAAGAAAATAAAGGGATTACTGAGAGCTGTCCATAATGAAGGCATGCAGGTGCTTTCTCTCACTGAGTCTCCCT
ATAGTGATGGAGAGGACCATTCTATTCAGCAGGTTTCAGAACCTTGGCTAGAAGAGAGAAAAGCTTACATCAATACAATCTCATCTCTAA
AGGATTTAATTACAAAGATGCAACTGCAAAGAGAAGCCGAGGTTTATGATAGTTCTCAATCTCATGAGAGCTTCTCAGACTGGCGAGGTG
AACTACTGCTTGCCCTTCAACAAGTTTTCTTAGAAGAGCGTAGTGTTTTACTAGCAGCATTTCGGACGGAGCTGACAGCTCTAGGTACTA
CAGATGCAGTTGGTTTACTAAACTGTTTGGAACAGAGAATACAAGAACAGGGTGTTGAATATCAAGCAGCTATGGAATGCCTCCAGAAAG
CAGATAGAAGGAGTTTGTTATCTGAAATTCAGGCACTGCATGCACAAATGAATGGTAGGAAAATTACTCTGAAAAGAGAACAAGAGAGTG
AGAAACCAAGCCAAGAACTCTTGGAATATAATATACAGCAGAAGCAGTCTCAAATGCTGGAGATGCAAGTGGAGCTCAGCAGTATGAAAG
ACAGAGCAACGGAACTGCAGGAGCAGCTGAGTTCTGAGAAAATGGTGGTTGCTGAACTGAAGAGTGAGCTTGCACAAACTAAATTGGAAC
TAGAAACAACACTCAAGGCACAGCATAAACACCTAAAAGAATTGGAGGCTTTCAGGTTGGAAGTTAAAGATAAGACAGATGAAGTACATT
TGCTTAATGACACATTAGCAAGTGAACAGAAAAAATCAAGAGAGCTCCAGTGGGCTTTGGAGAAAGAGAAAGCCAAGTTGGGACGCAGTG
AAGAACGGGATAAAGAAGAACTTGAGGATCTGAAGTTTTCACTTGAGAGTCAGAAACAAAGGAATCTTCAGCTAAATCTACTTTTGGAAC
AACAGAAACAACTACTGAACGAATCCCAGCAAAAAATAGAATCACAGAGAATGCTATATGATGCCCAGTTGTCAGAAGAACAAGGTCGAA
ACTTAGAGCTTCAGGTACTTCTTGAATCTGAGAAAGTTCGAATTCGGGAAATGAGTAGTACCCTAGATAGGGAGCGGGAATTGCACGCAC
AGCTGCAGAGCAGTGATGGTACTGGACAGTCTCGGCCACCCTTGCCCTCAGAGGACCTACTGAAAGAGCTGCAGAAACAGCTAGAGGAAA
AACACAGTCGCATAGTAGAATTGTTAAATGAGACTGAAAAATATAAACTGGATTCTTTGCAAACACGACAGCAAATGGAAAAAGATAGGC
AGGTTCACAGGAAAACACTGCAGACAGAACAGGAGGCCAACACTGAGGGACAGAAAAAAATGCATGAGCTCCAGTCCAAAGTGGAAGATC
TTCAGCGCCAGCTGGAAGAGAAAAGACAACAAGTTTATAAGTTAGACCTTGAAGGACAGCGACTACAAGGAATCATGCAGGAATTCCAGA
AGCAAGAACTAGAACGAGAAGAAAAACGAGAAAGTAGAAGAATTCTGTATCAGAACCTTAATGAGCCAACCACGTGGAGCTTAACCAGTG
ATAGAACTAGAAATTGGGTTCTTCAACAGAAAATAGAAGGAGAAACAAAAGAATCAAACTACGCTAAATTGATTGAAATGAATGGAGGAG
GAACCGGCTGTAATCATGAATTAGAAATGATCAGACAAAAGCTTCAATGTGTAGCTTCAAAACTACAGGTTCTACCCCAGAAAGCCTCTG
AGAGACTACAGTTTGAAACAGCAGATGATGAAGATTTCATTTGGGTTCAGGAAAATATTGATGAAATTATTTTACAACTACAGAAATTAA
CTGGCCAGCAAGGTGAAGAGCCCAGCTTGGTGTCCCCAAGTACTTCTTGTGGCTCATTGACTGAAAGACTACTGAGACAAAATGCTGAGC
TGACAGGGCATATCAGTCAACTGACTGAAGAGAAGAATGACTTAAGGAACATGGTTATGAAGCTGGAAGAGCAGATCAGGTGGTATCGAC
AGACAGGAGCTGGTAGAGATAATTCTTCCAGGTTTTCATTGAATGGTGGTGCCAACATTGAAGCCATCATTGCCTCTGAAAAAGAAGTAT
GGAACAGAGAAAAATTGACTCTCCAGAAATCTTTGAAAAGGGCAGAGGCTGAAGTATACAAACTGAAAGCTGAACTAAGAAATGACTCTT
TACTTCAAACTCTGAGCCCTGATTCTGAACATGTCACTTTAAAGAGAATTTATGGTAAATACTTGAGGGCAGAAAGTTTTCGAAAGGCTC
TCATTTACCAGAAGAAATACCTGCTGCTGTTACTGGGTGGGTTCCAGGAATGTGAAGATGCCACCTTGGCCCTGCTTGCCCGGATGGGGG
GGCAGCCAGCTTTCACGGATCTAGAGGTGATCACCAATCGCCCAAAGGGCTTCACCAGGTTTCGGTCGGCCGTCAGAGTATCCATTGCAA
TTTCCAGAATGAAATTTTTGGTTCGACGGTGGCATCGAGTCACAGGTTCTGTTTCCATCAATATTAACAGAGATGGCTTTGGACTGAATC
AAGGTGCAGAAAAGACTGACTCATTTTATCATTCTTCTGGTGGGCTGGAGTTATATGGAGAACCAAGACATACTACGTATCGCTCAAGAT
CAGATCTGGACTATATTAGGTCCCCTTTACCATTTCAGAATAGGTACCCAGGCACTCCAGCTGATTTCAATCCTGGTTCTTTAGCATGTT
CTCAGCTTCAGAATTACGATCCTGACAGAGCCCTAACAGATTATATCACTCGGCTAGAGGCACTGCAAAGACGACTTGGAACTATACAGT
CAGGTTCAACTACTCAATTTCATGCTGGCATGAGAAGATAATCCTTTGAAACATCATTAATTGAAGTGATTTTAAATAGATTTCCTTTTG
TAAATCAATGGTTCTTTTGTGCTTTTGTATTGTGAATATTCAATGGGACCAATATGAACACAGCTTATGATTGTATACAAATCCCTTGCC
AGCACATGAAAACAAACTGGAATTTGTATATATAAGCATTGTGTATGTATTCATGCACAATAATTATTGAATTACCTGTATATTTGTGGA
ATGCTAATTTAAAACATTAAATTATAAACCTTGTGTATTTATCAAATGGGTGAAAAGATTAAACTTTTACGCATTACAATACTGCTGAAT
GTGTAGCTCGAGGTGTCCTGCACTTTTCTTATAAGGCTACTGAAGTTACATGTTTTGCCTAATATATTCTACTGGTGATGAAGACAGATA
ATATCACTTGTAGAGACCTATTTTTGTATAATGGTAGAAGTTTTGAATTTTATGGGGTATTTTGTCAAGTACTGAAATAAAAATGACTTC

>In-frame_ENST00000407977_ENST00000359028_TCGA-HU-A4H5_RNF43_chr17_56492686_-_AKAP9_chr7_91674321_length(amino acids)=2168AA_start in transcript=1004_stop in transcript=7510
MKILLEVVKTTAAVEETIGRHVLGILDRSSKSQSSASLIWRSEAEASVKSCVHEEHTRVTDESIPSYSGSDMPRNDINMWSKVTEEGTEL
SQRLVRSGFAGTEIDPENEELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEELRERLHEESRARE
QLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKL
MKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLE
QQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEA
KPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAM
STQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQ
ELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSV
NVAIDHLSKDKPELEVVLTEDALKSLENQTYFKSFEENGKGSIINLETRLLQLESTVSAKDLELTQCYKQIKDMQEQGQFETEMLQKKIV
NLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLREDELGSDISALTLRISELESQVVEMHTSLILEKEQVEI
AEKNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQEELLV
KETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQESKKACMFEPLPIKLSKSIASQTDGTLKISSSNQTPQILVKNAGIQINLQSE
CSSEEVTEIISQFTEKIEKMQELHAAEILDMESRHISETETLKREHYVAVQLLKEECGTLKAVIQCLRSKEVFGFYNMCFSTLCDSGSDW
GQGIYLTHSQGFDIASEGRGEESESATDSFPKKIKGLLRAVHNEGMQVLSLTESPYSDGEDHSIQQVSEPWLEERKAYINTISSLKDLIT
KMQLQREAEVYDSSQSHESFSDWRGELLLALQQVFLEERSVLLAAFRTELTALGTTDAVGLLNCLEQRIQEQGVEYQAAMECLQKADRRS
LLSEIQALHAQMNGRKITLKREQESEKPSQELLEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTL
KAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQL
LNESQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHSRI
VELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQELE
REEKRESRRILYQNLNEPTTWSLTSDRTRNWVLQQKIEGETKESNYAKLIEMNGGGTGCNHELEMIRQKLQCVASKLQVLPQKASERLQF
ETADDEDFIWVQENIDEIILQLQKLTGQQGEEPSLVSPSTSCGSLTERLLRQNAELTGHISQLTEEKNDLRNMVMKLEEQIRWYRQTGAG
RDNSSRFSLNGGANIEAIIASEKEVWNREKLTLQKSLKRAEAEVYKLKAELRNDSLLQTLSPDSEHVTLKRIYGKYLRAESFRKALIYQK
KYLLLLLGGFQECEDATLALLARMGGQPAFTDLEVITNRPKGFTRFRSAVRVSIAISRMKFLVRRWHRVTGSVSININRDGFGLNQGAEK
TDSFYHSSGGLELYGEPRHTTYRSRSDLDYIRSPLPFQNRYPGTPADFNPGSLACSQLQNYDPDRALTDYITRLEALQRRLGTIQSGSTT

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for RNF43-AKAP9


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for RNF43-AKAP9


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for RNF43-AKAP9


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneRNF43C4310714SESSILE SERRATED POLYPOSIS CANCER SYNDROME6CLINGEN
HgeneRNF43C0009402Colorectal Carcinoma1CTD_human
HgeneRNF43C0009404Colorectal Neoplasms1CTD_human
HgeneRNF43C0014170Endometrial Neoplasms1CTD_human
HgeneRNF43C0023897Liver Diseases, Parasitic1CTD_human
HgeneRNF43C0024623Malignant neoplasm of stomach1CTD_human
HgeneRNF43C0033578Prostatic Neoplasms1CTD_human
HgeneRNF43C0038356Stomach Neoplasms1CTD_human
HgeneRNF43C0206698Cholangiocarcinoma1CGI;CTD_human
HgeneRNF43C0345905Intrahepatic Cholangiocarcinoma1CTD_human
HgeneRNF43C0376358Malignant neoplasm of prostate1CTD_human
HgeneRNF43C0476089Endometrial Carcinoma1CTD_human
HgeneRNF43C1708349Hereditary Diffuse Gastric Cancer1CTD_human
HgeneRNF43C2931456Prostate cancer, familial1CTD_human
HgeneRNF43C3805278Extrahepatic Cholangiocarcinoma1CTD_human
HgeneRNF43C4296896Hyperplastic polyposis syndrome1ORPHANET
HgeneRNF43C4722327PROSTATE CANCER, HEREDITARY, 11CTD_human
TgeneAKAP9C2678483Long Qt Syndrome 114CLINGEN;CTD_human;GENOMICS_ENGLAND;UNIPROT
TgeneAKAP9C0035828Romano-Ward Syndrome1ORPHANET
TgeneAKAP9C0037274Dermatologic disorders1CTD_human
TgeneAKAP9C0274861Arsenic Poisoning, Inorganic1CTD_human
TgeneAKAP9C0274862Nervous System, Organic Arsenic Poisoning1CTD_human
TgeneAKAP9C0311375Arsenic Poisoning1CTD_human
TgeneAKAP9C0751851Arsenic Encephalopathy1CTD_human
TgeneAKAP9C0751852Arsenic Induced Polyneuropathy1CTD_human
TgeneAKAP9C1142166Brugada Syndrome (disorder)1ORPHANET