FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:RPRD1A-AP2B1 (FusionGDB2 ID:76760)

Fusion Gene Summary for RPRD1A-AP2B1

check button Fusion gene summary
Fusion gene informationFusion gene name: RPRD1A-AP2B1
Fusion gene ID: 76760
HgeneTgene
Gene symbol

RPRD1A

AP2B1

Gene ID

55197

163

Gene nameregulation of nuclear pre-mRNA domain containing 1Aadaptor related protein complex 2 subunit beta 1
SynonymsHsT3101|P15RSADTB2|AP105B|AP2-BETA|CLAPB1
Cytomap

18q12.2

17q12

Type of geneprotein-codingprotein-coding
Descriptionregulation of nuclear pre-mRNA domain-containing protein 1ACDKN2B-related proteinCyclin-dependent kinase inhibitor 2B-related protein (p15INK4B-related protein)cyclin-dependent kinase 2B-inhibitor-related proteinp15INK4B-related proteinAP-2 complex subunit betaadapter-related protein complex 2 beta subunitadapter-related protein complex 2 subunit betaadaptin, beta 2 (beta)adaptor protein complex AP-2 subunit betaadaptor related protein complex 2 beta 1 subunitadaptor-related prote
Modification date2020031320200327
UniProtAcc.

P63010

Ensembl transtripts involved in fusion geneENST00000590898, ENST00000399022, 
ENST00000337059, ENST00000357384, 
ENST00000588737, ENST00000319040, 
ENST00000588459, 		ENST00000262325, 
ENST00000592545, ENST00000538556, 
ENST00000312678, ENST00000589344, 
ENST00000537622, ENST00000545922, 
Fusion gene scores* DoF score13 X 14 X 7=127414 X 18 X 9=2268
# samples 1719
** MAII scorelog2(17/1274*10)=-2.9057586261186
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(19/2268*10)=-3.57734931661128
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RPRD1A [Title/Abstract] AND AP2B1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRPRD1A(33647217)-AP2B1(33977549), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneAP2B1

GO:0072583

clathrin-dependent endocytosis

23676497


check buttonFusion gene breakpoints across RPRD1A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across AP2B1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-06-5415-01ARPRD1Achr18

33647217

-AP2B1chr17

33977549

+


Top

Fusion Gene ORF analysis for RPRD1A-AP2B1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5UTR-3CDSENST00000590898ENST00000262325RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
5UTR-3CDSENST00000590898ENST00000592545RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
5UTR-3CDSENST00000590898ENST00000538556RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
5UTR-3CDSENST00000590898ENST00000312678RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
5UTR-3CDSENST00000590898ENST00000589344RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
5UTR-3CDSENST00000590898ENST00000537622RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
5UTR-3UTRENST00000590898ENST00000545922RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
In-frameENST00000399022ENST00000262325RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
In-frameENST00000399022ENST00000592545RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
In-frameENST00000399022ENST00000538556RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
In-frameENST00000399022ENST00000312678RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
In-frameENST00000399022ENST00000589344RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
In-frameENST00000399022ENST00000537622RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
5CDS-3UTRENST00000399022ENST00000545922RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
intron-3CDSENST00000337059ENST00000262325RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
intron-3CDSENST00000337059ENST00000592545RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
intron-3CDSENST00000337059ENST00000538556RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
intron-3CDSENST00000337059ENST00000312678RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
intron-3CDSENST00000337059ENST00000589344RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
intron-3CDSENST00000337059ENST00000537622RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
intron-3UTRENST00000337059ENST00000545922RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
In-frameENST00000357384ENST00000262325RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
In-frameENST00000357384ENST00000592545RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
In-frameENST00000357384ENST00000538556RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
In-frameENST00000357384ENST00000312678RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
In-frameENST00000357384ENST00000589344RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
In-frameENST00000357384ENST00000537622RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
5CDS-3UTRENST00000357384ENST00000545922RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
5UTR-3CDSENST00000588737ENST00000262325RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
5UTR-3CDSENST00000588737ENST00000592545RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
5UTR-3CDSENST00000588737ENST00000538556RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
5UTR-3CDSENST00000588737ENST00000312678RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
5UTR-3CDSENST00000588737ENST00000589344RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
5UTR-3CDSENST00000588737ENST00000537622RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
5UTR-3UTRENST00000588737ENST00000545922RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
In-frameENST00000319040ENST00000262325RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
In-frameENST00000319040ENST00000592545RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
In-frameENST00000319040ENST00000538556RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
In-frameENST00000319040ENST00000312678RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
In-frameENST00000319040ENST00000589344RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
In-frameENST00000319040ENST00000537622RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
5CDS-3UTRENST00000319040ENST00000545922RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
intron-3CDSENST00000588459ENST00000262325RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
intron-3CDSENST00000588459ENST00000592545RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
intron-3CDSENST00000588459ENST00000538556RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
intron-3CDSENST00000588459ENST00000312678RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
intron-3CDSENST00000588459ENST00000589344RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
intron-3CDSENST00000588459ENST00000537622RPRD1Achr18

33647217

-AP2B1chr17

33977549

+
intron-3UTRENST00000588459ENST00000545922RPRD1Achr18

33647217

-AP2B1chr17

33977549

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000399022RPRD1Achr1833647217-ENST00000262325AP2B1chr1733977549+43193234101600396
ENST00000399022RPRD1Achr1833647217-ENST00000592545AP2B1chr1733977549+20303234101642410
ENST00000399022RPRD1Achr1833647217-ENST00000538556AP2B1chr1733977549+19883234101600396
ENST00000399022RPRD1Achr1833647217-ENST00000312678AP2B1chr1733977549+23193234101642410
ENST00000399022RPRD1Achr1833647217-ENST00000589344AP2B1chr1733977549+17093234101642410
ENST00000399022RPRD1Achr1833647217-ENST00000537622AP2B1chr1733977549+20333234101642410
ENST00000357384RPRD1Achr1833647217-ENST00000262325AP2B1chr1733977549+42993033901580396
ENST00000357384RPRD1Achr1833647217-ENST00000592545AP2B1chr1733977549+20103033901622410
ENST00000357384RPRD1Achr1833647217-ENST00000538556AP2B1chr1733977549+19683033901580396
ENST00000357384RPRD1Achr1833647217-ENST00000312678AP2B1chr1733977549+22993033901622410
ENST00000357384RPRD1Achr1833647217-ENST00000589344AP2B1chr1733977549+16893033901622410
ENST00000357384RPRD1Achr1833647217-ENST00000537622AP2B1chr1733977549+20133033901622410
ENST00000319040RPRD1Achr1833647217-ENST00000262325AP2B1chr1733977549+42993033901580396
ENST00000319040RPRD1Achr1833647217-ENST00000592545AP2B1chr1733977549+20103033901622410
ENST00000319040RPRD1Achr1833647217-ENST00000538556AP2B1chr1733977549+19683033901580396
ENST00000319040RPRD1Achr1833647217-ENST00000312678AP2B1chr1733977549+22993033901622410
ENST00000319040RPRD1Achr1833647217-ENST00000589344AP2B1chr1733977549+16893033901622410
ENST00000319040RPRD1Achr1833647217-ENST00000537622AP2B1chr1733977549+20133033901622410

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000399022ENST00000262325RPRD1Achr1833647217-AP2B1chr1733977549+0.0018126250.99818736
ENST00000399022ENST00000592545RPRD1Achr1833647217-AP2B1chr1733977549+0.002573560.99742645
ENST00000399022ENST00000538556RPRD1Achr1833647217-AP2B1chr1733977549+0.0023124960.99768746
ENST00000399022ENST00000312678RPRD1Achr1833647217-AP2B1chr1733977549+0.0020074970.9979925
ENST00000399022ENST00000589344RPRD1Achr1833647217-AP2B1chr1733977549+0.0024022080.99759775
ENST00000399022ENST00000537622RPRD1Achr1833647217-AP2B1chr1733977549+0.0025437230.99745625
ENST00000357384ENST00000262325RPRD1Achr1833647217-AP2B1chr1733977549+0.0018258750.9981741
ENST00000357384ENST00000592545RPRD1Achr1833647217-AP2B1chr1733977549+0.0028047040.99719524
ENST00000357384ENST00000538556RPRD1Achr1833647217-AP2B1chr1733977549+0.0026782840.9973218
ENST00000357384ENST00000312678RPRD1Achr1833647217-AP2B1chr1733977549+0.0021143790.99788564
ENST00000357384ENST00000589344RPRD1Achr1833647217-AP2B1chr1733977549+0.0028563140.9971437
ENST00000357384ENST00000537622RPRD1Achr1833647217-AP2B1chr1733977549+0.0027721410.99722785
ENST00000319040ENST00000262325RPRD1Achr1833647217-AP2B1chr1733977549+0.0018258750.9981741
ENST00000319040ENST00000592545RPRD1Achr1833647217-AP2B1chr1733977549+0.0028047040.99719524
ENST00000319040ENST00000538556RPRD1Achr1833647217-AP2B1chr1733977549+0.0026782840.9973218
ENST00000319040ENST00000312678RPRD1Achr1833647217-AP2B1chr1733977549+0.0021143790.99788564
ENST00000319040ENST00000589344RPRD1Achr1833647217-AP2B1chr1733977549+0.0028563140.9971437
ENST00000319040ENST00000537622RPRD1Achr1833647217-AP2B1chr1733977549+0.0027721410.99722785

Top

Fusion Genomic Features for RPRD1A-AP2B1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
RPRD1Achr1833647216-AP2B1chr1733977548+9.62E-091
RPRD1Achr1833647216-AP2B1chr1733977548+9.62E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for RPRD1A-AP2B1


check button Go to

FGviewer for the breakpoints of chr18:33647217-chr17:33977549

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.AP2B1

P63010

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. During long-term potentiation in hippocampal neurons, AP-2 is responsible for the endocytosis of ADAM10 (PubMed:23676497). The AP-2 beta subunit acts via its C-terminal appendage domain as a scaffolding platform for endocytic accessory proteins; at least some clathrin-associated sorting proteins (CLASPs) are recognized by their [DE]-X(1,2)-F-X-X-[FL]-X-X-X-R motif. The AP-2 beta subunit binds to clathrin heavy chain, promoting clathrin lattice assembly; clathrin displaces at least some CLASPs from AP2B1 which probably then can be positioned for further coat assembly. {ECO:0000269|PubMed:14745134, ECO:0000269|PubMed:14985334, ECO:0000269|PubMed:15473838, ECO:0000269|PubMed:19033387, ECO:0000269|PubMed:23676497}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneAP2B1chr18:33647217chr17:33977549ENST000002623251121576_716512.0938.0Compositional biasNote=Pro-rich (stalk region)
TgeneAP2B1chr18:33647217chr17:33977549ENST000003126781122576_716512.0952.0Compositional biasNote=Pro-rich (stalk region)
TgeneAP2B1chr18:33647217chr17:33977549ENST000005376221122576_716512.0952.0Compositional biasNote=Pro-rich (stalk region)
TgeneAP2B1chr18:33647217chr17:33977549ENST000005385561222576_716455.0881.0Compositional biasNote=Pro-rich (stalk region)
TgeneAP2B1chr18:33647217chr17:33977549ENST000005893441122576_716512.0952.0Compositional biasNote=Pro-rich (stalk region)

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRPRD1Achr18:33647217chr17:33977549ENST00000319040-17244_28650.333333333333336290.0Coiled coilOntology_term=ECO:0000255
HgeneRPRD1Achr18:33647217chr17:33977549ENST00000337059-18244_2860.0522.3333333333334Coiled coilOntology_term=ECO:0000255
HgeneRPRD1Achr18:33647217chr17:33977549ENST00000357384-18244_28650.333333333333336471.6666666666667Coiled coilOntology_term=ECO:0000255
HgeneRPRD1Achr18:33647217chr17:33977549ENST00000399022-17244_28650.333333333333336313.0Coiled coilOntology_term=ECO:0000255
HgeneRPRD1Achr18:33647217chr17:33977549ENST00000588737-18244_2860277.0Coiled coilOntology_term=ECO:0000255
HgeneRPRD1Achr18:33647217chr17:33977549ENST00000590898-19244_2860488.6666666666667Coiled coilOntology_term=ECO:0000255
HgeneRPRD1Achr18:33647217chr17:33977549ENST00000319040-172_13350.333333333333336290.0DomainCID
HgeneRPRD1Achr18:33647217chr17:33977549ENST00000337059-182_1330.0522.3333333333334DomainCID
HgeneRPRD1Achr18:33647217chr17:33977549ENST00000357384-182_13350.333333333333336471.6666666666667DomainCID
HgeneRPRD1Achr18:33647217chr17:33977549ENST00000399022-172_13350.333333333333336313.0DomainCID
HgeneRPRD1Achr18:33647217chr17:33977549ENST00000588737-182_1330277.0DomainCID
HgeneRPRD1Achr18:33647217chr17:33977549ENST00000590898-192_1330488.6666666666667DomainCID


Top

Fusion Gene Sequence for RPRD1A-AP2B1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000399022_ENST00000262325_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(transcript)=4319nt_BP=323nt
ACTGCCGGCCGGACGCCATCTTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGG
GGGCGAGGCCGCAGCTAGGGCGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGC
CTTCTCTGAGGCGGCGCTGGAGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCA
CCGTAAACACTCGCGTCCCATCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGATTCTGATAATCCTGACCTTCGAGACCGGGGCTATA
TTTATTGGCGCCTTCTCTCAACTGACCCTGTTACAGCTAAAGAAGTAGTCTTGTCTGAGAAGCCACTGATCTCTGAGGAGACGGACCTTA
TTGAGCCAACTCTGCTGGATGAGCTAATCTGCCACATTGGTTCTTTGGCCTCTGTGTATCATAAGCCTCCCAATGCTTTTGTGGAAGGAA
GTCATGGAATTCATCGTAAACACTTGCCAATTCATCATGGGAGCACTGATGCAGGTGACAGCCCTGTTGGCACTACCACTGCAACGAACC
TGGAACAGCCTCAGGTTATCCCCTCTCAAGGTGATCTTCTAGGGGATCTTTTAAACCTTGACCTCGGTCCCCCAGTCAATGTGCCACAGG
TGTCCTCCATGCAGATGGGAGCAGTGGATCTCCTAGGAGGAGGACTAGATAGTCTGGTGGGACAATCCTTCATCCCATCATCGGTGCCTG
CAACCTTTGCTCCTTCACCTACACCTGCTGTGGTCAGCAGTGGACTGAATGACCTGTTTGAACTCTCCACAGGGATAGGCATGGCACCTG
GTGGATATGTGGCTCCTAAGGCTGTCTGGCTACCTGCAGTAAAGGCTAAAGGCTTGGAGATTTCCGGAACATTTACTCACCGCCAAGGGC
ACATCTATATGGAAATGAACTTCACCAATAAAGCTCTGCAGCACATGACAGATTTTGCAATCCAGTTTAACAAAAATAGCTTTGGTGTCA
TCCCCAGCACTCCTCTGGCCATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCA
TGAAGATGGAACCTCTGAATAACCTCCAGGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGC
TTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTCCTTGCAACATGGAAGGATATTCCCAATGAAAATGAACTTCAGTTTCAGATTA
AGGAATGTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACAACAATGTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGG
ACATGCTGTACCAATCCCTGAAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACGTATCCAGCCAGGAAACCCCAATTACACGCTGT
CACTGAAGTGTAGAGCTCCTGAAGTCTCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAACTAACAAGACTGGTCCAGTACCC
TTCAACCATGCTGTGATCGGTGCAAGTCAAGAACTCTTAACTGGAAGAAATTGTATTGCTGCGTAGAATCTGAACACACTGAGGCCACCT
AGCAAGGTAGTAACTAGTCTAACCTGTGCTAACATTAGGGCACAACCTGTTGGATAGTTTTAGCTTCCTGTGAACATTTGTAACCACTGC
TTCAGTCACCTCCCACCTCTTGCCACCTGCTGCTGCTATCTGTCCTTACTTGTGGGCTTCTCCATGCTGTGCCAATGGCTGGCTTTTTCT
ACACCCTCTTTTGAGTGTAGTTTGGTATTTTGTAATTGAGAGCTCATTTCAAAAGCAGAAAAAGACAACAAATATTAAAGCAAGGAAAAG
TGTAACTGAAACACTGCACTTTACTGTTTTATACTTTTGTACATATGAGAAATCAAGGGATTAGTGCAACCAGTAGAAAGCATTGAAATG
ACTGTCATTAACCACACAGTCCTGGAGGCAGAGATGCAGTTACCTACCCTAGCTTTTGATGGGTTCTCTTACCTGTAGTAGCCTTATCCC
TGGTCATTTGGATTTTCAGTTTGCTTTTTTCTTTTTTTCCCCTCCAAACTCCTTTTCCTTGGCCAAGCCTTCATGCTTCCCCCTTTCCAT
ATTATAATCTCATTTGATTGCTCTGCAGTTGGGAACGGTGATCTTCTTGAATGATGTTTCAGTGTGCAAAAACTATAGAGCCTGTCAGCA
CCAAAGCTGACAGAAGTTATACCTTACTCCTTTCCTTTCCCCTGAACAAACCTGCTAATCCCACTAATTCAGGAATTTGAGTAGAGATGG
GGAACAAGAACCCAGATGCTGTCCCCTCACCCCCTCTCCTGTATTTCTCAGGTCCAGTTCAAATCTAAAATTCTACTTTTAGAGTTGAAA
CAGAGTAATAACTTATCTAACCCTCTTTTCCTACAAAGGAGAAAGATAAAAGGCACAAAGGTTACCGCCAAGGCCCGTCAGCTGTGTAGT
GGCAAAGCCGAGACCGAGTCTCCTAAGTCCCCGTCAGTGTGGTTTTCACCACAGGACTGTCTCTTGTCGTTTTCCCCTAATGCCTTCTCC
TGCCTTTTCTGTGCCTAGTTTTTGGCTCTTCACATATTCCATATTGATTTTGACGCTCTGTATATTGGCATCAGGTGGCAGCTGAATATC
TTTTGAATTACTCGAAGGTAAAGCCAGATGCCAGAATGAAGGTGTAGCCAGTGTTTCCCATATGCCCCTGGAGCCCCACTTATTGAGGCC
AGCAGAATAGGTGCAGAGATGAAGTGAGCTTAGAGATGTTGCAAATGCTCTTTATCCCTTCAGCTCTCTGATCTGCTCTTTCTTCATGAT
ACTTAGTCTGCAGGGCATATTAAGATCATCCCAGAGGTTCAGGCAGTTCCTGTCATCTCTGAAAAGACTGGGGGATATGAAATCTTCCCC
CTACCCCACTTAATGCGTTGGATATGATTTTTCAAAGAATGCTTCATGCCCAAAATACCAGCCTGTTTAGCAGTGTTACACTGTTTGATC
TGCGGGCACTTGTTGCATTGCCTGGCACCCAATATTCAGGGTCCATGACTAAGACTGGTCTTCTCAGATGCCCTGCTTAAATCAGGGGCA
CTTCAGGCTCCACAGGCGTCATGTTGGACTGAGACCTAACTCACTGGACTCAGAGGAGGAATCGTGGAAAACAAGAGCAAAACTACCCCA
CACCCCTATTTCATGTCTGAAATAACCCTGTTTCATACCAGTTGCAAAGCTTGTGGGGAGCGGTCCCACAAAGCACTTTCTTAAACCTTG
AGAATCTCCAAGAGAAAAATATTTGGGGAAGGAGGGAGGAAATATGTCCCTTGCACACCACCCCTGAAGCACATGGCAGTAGGAAACAGC
ATAGGATTGTATGTGGGAGGTGGATAGGTCGGTGATGTGTGGAGCGGAAAAGCAGGTTGGTAAAGTTCCCTTCTTGGGACTTATTCCTGG
AGTCAGTGGATACAAGTAGTGCAGAAGGTTCACACTGCAAATAGTGTTCTCATCTCAAAGCAAACTATCATTCCAGAAGGAAAAGTGTGT
CAGGGCAAGCAGACAACACAATTTCCTATCAGAATATGTCCCTCAACCCCCGAAACAAGGCTTCTCTCAGCCTCCCCACCAGTGATGGAT
AACAGCTCCTATTCTCAGCTGACCTGACTGAGCCAACCCATGAACTCTTCACTCCTTGGGGAAGCCACCTCCCATCACACCCCTGAGCAG
AGTTAGGGAGGAATTCTACTTCCCATAAAAGGACCTCTCCTGAGAGGCAAAACCTGTTGCCTCCACCACGGCTTCCCTCTTGGCTCATTC
CAAGCTTGGCCAAATTGGGGAAGTGGGATGGAGGTTGCCCTGCATCCCCCCTCCTCTGCCTGAGTGTGTCTTTGTAATGTCAGCTGGCAT
CATACAAAGAGCAGGAGAAGCAAACACCCAGAACTCTTTTGCTGGTCAGAGATTCCCTGAGTGTCTGTCCTCACCCAAGCCTGCTCTGTG
TCTGTGTTGTGAAGCTTGAGACTCTGGAAAGAAATGGGGAGGGGGGGCAGGGGAAATGTTGCCCTAAGAATGCTTCTCATTCCTCTGTTC

>In-frame_ENST00000399022_ENST00000262325_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(amino acids)=396AA_start in transcript=410_stop in transcript=1600
MSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQGDLLGDL
LNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGYVAPKAVWLPAVKAK
GLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNI
DVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDMLYQSLKLTNGIWILA

--------------------------------------------------------------
>In-frame_ENST00000399022_ENST00000592545_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(transcript)=2030nt_BP=323nt
ACTGCCGGCCGGACGCCATCTTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGG
GGGCGAGGCCGCAGCTAGGGCGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGC
CTTCTCTGAGGCGGCGCTGGAGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCA
CCGTAAACACTCGCGTCCCATCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGATTCTGATAATCCTGACCTTCGAGACCGGGGCTATA
TTTATTGGCGCCTTCTCTCAACTGACCCTGTTACAGCTAAAGAAGTAGTCTTGTCTGAGAAGCCACTGATCTCTGAGGAGACGGACCTTA
TTGAGCCAACTCTGCTGGATGAGCTAATCTGCCACATTGGTTCTTTGGCCTCTGTGTATCATAAGCCTCCCAATGCTTTTGTGGAAGGAA
GTCATGGAATTCATCGTAAACACTTGCCAATTCATCATGGGAGCACTGATGCAGGTGACAGCCCTGTTGGCACTACCACTGCAACGAACC
TGGAACAGCCTCAGGTTATCCCCTCTCAAGGTGATCTTCTAGGGGATCTTTTAAACCTTGACCTCGGTCCCCCAGTCAATGTGCCACAGG
TGTCCTCCATGCAGATGGGAGCAGTGGATCTCCTAGGAGGAGGACTAGATAGTCTGCTTGGCAGTGACCTTGGCGGGGGCATTGGAGGAA
GTCCGGCAGTGGGACAATCCTTCATCCCATCATCGGTGCCTGCAACCTTTGCTCCTTCACCTACACCTGCTGTGGTCAGCAGTGGACTGA
ATGACCTGTTTGAACTCTCCACAGGGATAGGCATGGCACCTGGTGGATATGTGGCTCCTAAGGCTGTCTGGCTACCTGCAGTAAAGGCTA
AAGGCTTGGAGATTTCCGGAACATTTACTCACCGCCAAGGGCACATCTATATGGAAATGAACTTCACCAATAAAGCTCTGCAGCACATGA
CAGATTTTGCAATCCAGTTTAACAAAAATAGCTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCACTGATGCCAAACCAGA
GCATTGATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTGGCTGTGAAAAACAATA
TCGATGTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTCCTTGCAACAT
GGAAGGATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACA
ACAATGTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAATGGCATTTGGATTTTGG
CCGAACTACGTATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAATACATCTATCAGGTCT
ACGACAGCATTTTGAAAAACTAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCGGTGCAAGTCAAGAACTCTTAACTGGAAGA
AATTGTATTGCTGCGTAGAATCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTCTAACCTGTGCTAACATTAGGGCACAACCT
GTTGGATAGTTTTAGCTTCCTGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTCTTGCCACCTGCTGCTGCTATCTGTCCTTA
CTTGTGGGCTTCTCCATGCTGTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTAGTTTGGTATTTTGTAATTGAGAGCTCATT

>In-frame_ENST00000399022_ENST00000592545_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(amino acids)=410AA_start in transcript=410_stop in transcript=1642
MSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQGDLLGDL
LNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLLGSDLGGGIGGSPAVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGY
VAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKM
EPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDML

--------------------------------------------------------------
>In-frame_ENST00000399022_ENST00000538556_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(transcript)=1988nt_BP=323nt
ACTGCCGGCCGGACGCCATCTTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGG
GGGCGAGGCCGCAGCTAGGGCGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGC
CTTCTCTGAGGCGGCGCTGGAGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCA
CCGTAAACACTCGCGTCCCATCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGATTCTGATAATCCTGACCTTCGAGACCGGGGCTATA
TTTATTGGCGCCTTCTCTCAACTGACCCTGTTACAGCTAAAGAAGTAGTCTTGTCTGAGAAGCCACTGATCTCTGAGGAGACGGACCTTA
TTGAGCCAACTCTGCTGGATGAGCTAATCTGCCACATTGGTTCTTTGGCCTCTGTGTATCATAAGCCTCCCAATGCTTTTGTGGAAGGAA
GTCATGGAATTCATCGTAAACACTTGCCAATTCATCATGGGAGCACTGATGCAGGTGACAGCCCTGTTGGCACTACCACTGCAACGAACC
TGGAACAGCCTCAGGTTATCCCCTCTCAAGGTGATCTTCTAGGGGATCTTTTAAACCTTGACCTCGGTCCCCCAGTCAATGTGCCACAGG
TGTCCTCCATGCAGATGGGAGCAGTGGATCTCCTAGGAGGAGGACTAGATAGTCTGGTGGGACAATCCTTCATCCCATCATCGGTGCCTG
CAACCTTTGCTCCTTCACCTACACCTGCTGTGGTCAGCAGTGGACTGAATGACCTGTTTGAACTCTCCACAGGGATAGGCATGGCACCTG
GTGGATATGTGGCTCCTAAGGCTGTCTGGCTACCTGCAGTAAAGGCTAAAGGCTTGGAGATTTCCGGAACATTTACTCACCGCCAAGGGC
ACATCTATATGGAAATGAACTTCACCAATAAAGCTCTGCAGCACATGACAGATTTTGCAATCCAGTTTAACAAAAATAGCTTTGGTGTCA
TCCCCAGCACTCCTCTGGCCATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCA
TGAAGATGGAACCTCTGAATAACCTCCAGGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGC
TTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTCCTTGCAACATGGAAGGATATTCCCAATGAAAATGAACTTCAGTTTCAGATTA
AGGAATGTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACAACAATGTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGG
ACATGCTGTACCAATCCCTGAAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACGTATCCAGCCAGGAAACCCCAATTACACGCTGT
CACTGAAGTGTAGAGCTCCTGAAGTCTCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAACTAACAAGACTGGTCCAGTACCC
TTCAACCATGCTGTGATCGGTGCAAGTCAAGAACTCTTAACTGGAAGAAATTGTATTGCTGCGTAGAATCTGAACACACTGAGGCCACCT
AGCAAGGTAGTAACTAGTCTAACCTGTGCTAACATTAGGGCACAACCTGTTGGATAGTTTTAGCTTCCTGTGAACATTTGTAACCACTGC
TTCAGTCACCTCCCACCTCTTGCCACCTGCTGCTGCTATCTGTCCTTACTTGTGGGCTTCTCCATGCTGTGCCAATGGCTGGCTTTTTCT
ACACCCTCTTTTGAGTGTAGTTTGGTATTTTGTAATTGAGAGCTCATTTCAAAAGCAGAAAAAGACAACAAATATTAAAGCAAGGAAAAG

>In-frame_ENST00000399022_ENST00000538556_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(amino acids)=396AA_start in transcript=410_stop in transcript=1600
MSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQGDLLGDL
LNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGYVAPKAVWLPAVKAK
GLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNI
DVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDMLYQSLKLTNGIWILA

--------------------------------------------------------------
>In-frame_ENST00000399022_ENST00000312678_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(transcript)=2319nt_BP=323nt
ACTGCCGGCCGGACGCCATCTTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGG
GGGCGAGGCCGCAGCTAGGGCGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGC
CTTCTCTGAGGCGGCGCTGGAGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCA
CCGTAAACACTCGCGTCCCATCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGATTCTGATAATCCTGACCTTCGAGACCGGGGCTATA
TTTATTGGCGCCTTCTCTCAACTGACCCTGTTACAGCTAAAGAAGTAGTCTTGTCTGAGAAGCCACTGATCTCTGAGGAGACGGACCTTA
TTGAGCCAACTCTGCTGGATGAGCTAATCTGCCACATTGGTTCTTTGGCCTCTGTGTATCATAAGCCTCCCAATGCTTTTGTGGAAGGAA
GTCATGGAATTCATCGTAAACACTTGCCAATTCATCATGGGAGCACTGATGCAGGTGACAGCCCTGTTGGCACTACCACTGCAACGAACC
TGGAACAGCCTCAGGTTATCCCCTCTCAAGGTGATCTTCTAGGGGATCTTTTAAACCTTGACCTCGGTCCCCCAGTCAATGTGCCACAGG
TGTCCTCCATGCAGATGGGAGCAGTGGATCTCCTAGGAGGAGGACTAGATAGTCTGCTTGGCAGTGACCTTGGCGGGGGCATTGGAGGAA
GTCCGGCAGTGGGACAATCCTTCATCCCATCATCGGTGCCTGCAACCTTTGCTCCTTCACCTACACCTGCTGTGGTCAGCAGTGGACTGA
ATGACCTGTTTGAACTCTCCACAGGGATAGGCATGGCACCTGGTGGATATGTGGCTCCTAAGGCTGTCTGGCTACCTGCAGTAAAGGCTA
AAGGCTTGGAGATTTCCGGAACATTTACTCACCGCCAAGGGCACATCTATATGGAAATGAACTTCACCAATAAAGCTCTGCAGCACATGA
CAGATTTTGCAATCCAGTTTAACAAAAATAGCTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCACTGATGCCAAACCAGA
GCATTGATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTGGCTGTGAAAAACAATA
TCGATGTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTCCTTGCAACAT
GGAAGGATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACA
ACAATGTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAATGGCATTTGGATTTTGG
CCGAACTACGTATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAATACATCTATCAGGTCT
ACGACAGCATTTTGAAAAACTAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCGGTGCAAGTCAAGAACTCTTAACTGGAAGA
AATTGTATTGCTGCGTAGAATCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTCTAACCTGTGCTAACATTAGGGCACAACCT
GTTGGATAGTTTTAGCTTCCTGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTCTTGCCACCTGCTGCTGCTATCTGTCCTTA
CTTGTGGGCTTCTCCATGCTGTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTAGTTTGGTATTTTGTAATTGAGAGCTCATT
TCAAAAGCAGAAAAAGACAACAAATATTAAAGCAAGGAAAAGTGTAACTGAAACACTGCACTTTACTGTTTTATACTTTTGTACATATGA
GAAATCAAGGGATTAGTGCAACCAGTAGAAAGCATTGAAATGACTGTCATTAACCACACAGTCCTGGAGGCAGAGATGCAGTTACCTACC
CTAGCTTTTGATGGGTTCTCTTACCTGTAGTAGCCTTATCCCTGGTCATTTGGATTTTCAGTTTGCTTTTTTCTTTTTTTCCCCTCCAAA

>In-frame_ENST00000399022_ENST00000312678_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(amino acids)=410AA_start in transcript=410_stop in transcript=1642
MSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQGDLLGDL
LNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLLGSDLGGGIGGSPAVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGY
VAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKM
EPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDML

--------------------------------------------------------------
>In-frame_ENST00000399022_ENST00000589344_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(transcript)=1709nt_BP=323nt
ACTGCCGGCCGGACGCCATCTTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGG
GGGCGAGGCCGCAGCTAGGGCGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGC
CTTCTCTGAGGCGGCGCTGGAGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCA
CCGTAAACACTCGCGTCCCATCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGATTCTGATAATCCTGACCTTCGAGACCGGGGCTATA
TTTATTGGCGCCTTCTCTCAACTGACCCTGTTACAGCTAAAGAAGTAGTCTTGTCTGAGAAGCCACTGATCTCTGAGGAGACGGACCTTA
TTGAGCCAACTCTGCTGGATGAGCTAATCTGCCACATTGGTTCTTTGGCCTCTGTGTATCATAAGCCTCCCAATGCTTTTGTGGAAGGAA
GTCATGGAATTCATCGTAAACACTTGCCAATTCATCATGGGAGCACTGATGCAGGTGACAGCCCTGTTGGCACTACCACTGCAACGAACC
TGGAACAGCCTCAGGTTATCCCCTCTCAAGGTGATCTTCTAGGGGATCTTTTAAACCTTGACCTCGGTCCCCCAGTCAATGTGCCACAGG
TGTCCTCCATGCAGATGGGAGCAGTGGATCTCCTAGGAGGAGGACTAGATAGTCTGCTTGGCAGTGACCTTGGCGGGGGCATTGGAGGAA
GTCCGGCAGTGGGACAATCCTTCATCCCATCATCGGTGCCTGCAACCTTTGCTCCTTCACCTACACCTGCTGTGGTCAGCAGTGGACTGA
ATGACCTGTTTGAACTCTCCACAGGGATAGGCATGGCACCTGGTGGATATGTGGCTCCTAAGGCTGTCTGGCTACCTGCAGTAAAGGCTA
AAGGCTTGGAGATTTCCGGAACATTTACTCACCGCCAAGGGCACATCTATATGGAAATGAACTTCACCAATAAAGCTCTGCAGCACATGA
CAGATTTTGCAATCCAGTTTAACAAAAATAGCTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCACTGATGCCAAACCAGA
GCATTGATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTGGCTGTGAAAAACAATA
TCGATGTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTCCTTGCAACAT
GGAAGGATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACA
ACAATGTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAATGGCATTTGGATTTTGG
CCGAACTACGTATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAATACATCTATCAGGTCT

>In-frame_ENST00000399022_ENST00000589344_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(amino acids)=410AA_start in transcript=410_stop in transcript=1642
MSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQGDLLGDL
LNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLLGSDLGGGIGGSPAVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGY
VAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKM
EPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDML

--------------------------------------------------------------
>In-frame_ENST00000399022_ENST00000537622_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(transcript)=2033nt_BP=323nt
ACTGCCGGCCGGACGCCATCTTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGG
GGGCGAGGCCGCAGCTAGGGCGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGC
CTTCTCTGAGGCGGCGCTGGAGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCA
CCGTAAACACTCGCGTCCCATCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGATTCTGATAATCCTGACCTTCGAGACCGGGGCTATA
TTTATTGGCGCCTTCTCTCAACTGACCCTGTTACAGCTAAAGAAGTAGTCTTGTCTGAGAAGCCACTGATCTCTGAGGAGACGGACCTTA
TTGAGCCAACTCTGCTGGATGAGCTAATCTGCCACATTGGTTCTTTGGCCTCTGTGTATCATAAGCCTCCCAATGCTTTTGTGGAAGGAA
GTCATGGAATTCATCGTAAACACTTGCCAATTCATCATGGGAGCACTGATGCAGGTGACAGCCCTGTTGGCACTACCACTGCAACGAACC
TGGAACAGCCTCAGGTTATCCCCTCTCAAGGTGATCTTCTAGGGGATCTTTTAAACCTTGACCTCGGTCCCCCAGTCAATGTGCCACAGG
TGTCCTCCATGCAGATGGGAGCAGTGGATCTCCTAGGAGGAGGACTAGATAGTCTGCTTGGCAGTGACCTTGGCGGGGGCATTGGAGGAA
GTCCGGCAGTGGGACAATCCTTCATCCCATCATCGGTGCCTGCAACCTTTGCTCCTTCACCTACACCTGCTGTGGTCAGCAGTGGACTGA
ATGACCTGTTTGAACTCTCCACAGGGATAGGCATGGCACCTGGTGGATATGTGGCTCCTAAGGCTGTCTGGCTACCTGCAGTAAAGGCTA
AAGGCTTGGAGATTTCCGGAACATTTACTCACCGCCAAGGGCACATCTATATGGAAATGAACTTCACCAATAAAGCTCTGCAGCACATGA
CAGATTTTGCAATCCAGTTTAACAAAAATAGCTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCACTGATGCCAAACCAGA
GCATTGATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTGGCTGTGAAAAACAATA
TCGATGTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTCCTTGCAACAT
GGAAGGATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACA
ACAATGTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAATGGCATTTGGATTTTGG
CCGAACTACGTATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAATACATCTATCAGGTCT
ACGACAGCATTTTGAAAAACTAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCGGTGCAAGTCAAGAACTCTTAACTGGAAGA
AATTGTATTGCTGCGTAGAATCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTCTAACCTGTGCTAACATTAGGGCACAACCT
GTTGGATAGTTTTAGCTTCCTGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTCTTGCCACCTGCTGCTGCTATCTGTCCTTA
CTTGTGGGCTTCTCCATGCTGTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTAGTTTGGTATTTTGTAATTGAGAGCTCATT

>In-frame_ENST00000399022_ENST00000537622_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(amino acids)=410AA_start in transcript=410_stop in transcript=1642
MSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQGDLLGDL
LNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLLGSDLGGGIGGSPAVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGY
VAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKM
EPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDML

--------------------------------------------------------------
>In-frame_ENST00000357384_ENST00000262325_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(transcript)=4299nt_BP=303nt
TTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGGGGGCGAGGCCGCAGCTAGGG
CGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGCCTTCTCTGAGGCGGCGCTGG
AGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCACCGTAAACACTCGCGTCCCA
TCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGATTCTGATAATCCTGACCTTCGAGACCGGGGCTATATTTATTGGCGCCTTCTCTCA
ACTGACCCTGTTACAGCTAAAGAAGTAGTCTTGTCTGAGAAGCCACTGATCTCTGAGGAGACGGACCTTATTGAGCCAACTCTGCTGGAT
GAGCTAATCTGCCACATTGGTTCTTTGGCCTCTGTGTATCATAAGCCTCCCAATGCTTTTGTGGAAGGAAGTCATGGAATTCATCGTAAA
CACTTGCCAATTCATCATGGGAGCACTGATGCAGGTGACAGCCCTGTTGGCACTACCACTGCAACGAACCTGGAACAGCCTCAGGTTATC
CCCTCTCAAGGTGATCTTCTAGGGGATCTTTTAAACCTTGACCTCGGTCCCCCAGTCAATGTGCCACAGGTGTCCTCCATGCAGATGGGA
GCAGTGGATCTCCTAGGAGGAGGACTAGATAGTCTGGTGGGACAATCCTTCATCCCATCATCGGTGCCTGCAACCTTTGCTCCTTCACCT
ACACCTGCTGTGGTCAGCAGTGGACTGAATGACCTGTTTGAACTCTCCACAGGGATAGGCATGGCACCTGGTGGATATGTGGCTCCTAAG
GCTGTCTGGCTACCTGCAGTAAAGGCTAAAGGCTTGGAGATTTCCGGAACATTTACTCACCGCCAAGGGCACATCTATATGGAAATGAAC
TTCACCAATAAAGCTCTGCAGCACATGACAGATTTTGCAATCCAGTTTAACAAAAATAGCTTTGGTGTCATCCCCAGCACTCCTCTGGCC
ATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAAT
AACCTCCAGGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAA
ATGGAGCGCCAGGTCTTCCTTGCAACATGGAAGGATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCT
GACACTGTTTCCAGCAAGTTGCAAAACAACAATGTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTG
AAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACGTATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCT
GAAGTCTCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAACTAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCGG
TGCAAGTCAAGAACTCTTAACTGGAAGAAATTGTATTGCTGCGTAGAATCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTCT
AACCTGTGCTAACATTAGGGCACAACCTGTTGGATAGTTTTAGCTTCCTGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTCT
TGCCACCTGCTGCTGCTATCTGTCCTTACTTGTGGGCTTCTCCATGCTGTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTAG
TTTGGTATTTTGTAATTGAGAGCTCATTTCAAAAGCAGAAAAAGACAACAAATATTAAAGCAAGGAAAAGTGTAACTGAAACACTGCACT
TTACTGTTTTATACTTTTGTACATATGAGAAATCAAGGGATTAGTGCAACCAGTAGAAAGCATTGAAATGACTGTCATTAACCACACAGT
CCTGGAGGCAGAGATGCAGTTACCTACCCTAGCTTTTGATGGGTTCTCTTACCTGTAGTAGCCTTATCCCTGGTCATTTGGATTTTCAGT
TTGCTTTTTTCTTTTTTTCCCCTCCAAACTCCTTTTCCTTGGCCAAGCCTTCATGCTTCCCCCTTTCCATATTATAATCTCATTTGATTG
CTCTGCAGTTGGGAACGGTGATCTTCTTGAATGATGTTTCAGTGTGCAAAAACTATAGAGCCTGTCAGCACCAAAGCTGACAGAAGTTAT
ACCTTACTCCTTTCCTTTCCCCTGAACAAACCTGCTAATCCCACTAATTCAGGAATTTGAGTAGAGATGGGGAACAAGAACCCAGATGCT
GTCCCCTCACCCCCTCTCCTGTATTTCTCAGGTCCAGTTCAAATCTAAAATTCTACTTTTAGAGTTGAAACAGAGTAATAACTTATCTAA
CCCTCTTTTCCTACAAAGGAGAAAGATAAAAGGCACAAAGGTTACCGCCAAGGCCCGTCAGCTGTGTAGTGGCAAAGCCGAGACCGAGTC
TCCTAAGTCCCCGTCAGTGTGGTTTTCACCACAGGACTGTCTCTTGTCGTTTTCCCCTAATGCCTTCTCCTGCCTTTTCTGTGCCTAGTT
TTTGGCTCTTCACATATTCCATATTGATTTTGACGCTCTGTATATTGGCATCAGGTGGCAGCTGAATATCTTTTGAATTACTCGAAGGTA
AAGCCAGATGCCAGAATGAAGGTGTAGCCAGTGTTTCCCATATGCCCCTGGAGCCCCACTTATTGAGGCCAGCAGAATAGGTGCAGAGAT
GAAGTGAGCTTAGAGATGTTGCAAATGCTCTTTATCCCTTCAGCTCTCTGATCTGCTCTTTCTTCATGATACTTAGTCTGCAGGGCATAT
TAAGATCATCCCAGAGGTTCAGGCAGTTCCTGTCATCTCTGAAAAGACTGGGGGATATGAAATCTTCCCCCTACCCCACTTAATGCGTTG
GATATGATTTTTCAAAGAATGCTTCATGCCCAAAATACCAGCCTGTTTAGCAGTGTTACACTGTTTGATCTGCGGGCACTTGTTGCATTG
CCTGGCACCCAATATTCAGGGTCCATGACTAAGACTGGTCTTCTCAGATGCCCTGCTTAAATCAGGGGCACTTCAGGCTCCACAGGCGTC
ATGTTGGACTGAGACCTAACTCACTGGACTCAGAGGAGGAATCGTGGAAAACAAGAGCAAAACTACCCCACACCCCTATTTCATGTCTGA
AATAACCCTGTTTCATACCAGTTGCAAAGCTTGTGGGGAGCGGTCCCACAAAGCACTTTCTTAAACCTTGAGAATCTCCAAGAGAAAAAT
ATTTGGGGAAGGAGGGAGGAAATATGTCCCTTGCACACCACCCCTGAAGCACATGGCAGTAGGAAACAGCATAGGATTGTATGTGGGAGG
TGGATAGGTCGGTGATGTGTGGAGCGGAAAAGCAGGTTGGTAAAGTTCCCTTCTTGGGACTTATTCCTGGAGTCAGTGGATACAAGTAGT
GCAGAAGGTTCACACTGCAAATAGTGTTCTCATCTCAAAGCAAACTATCATTCCAGAAGGAAAAGTGTGTCAGGGCAAGCAGACAACACA
ATTTCCTATCAGAATATGTCCCTCAACCCCCGAAACAAGGCTTCTCTCAGCCTCCCCACCAGTGATGGATAACAGCTCCTATTCTCAGCT
GACCTGACTGAGCCAACCCATGAACTCTTCACTCCTTGGGGAAGCCACCTCCCATCACACCCCTGAGCAGAGTTAGGGAGGAATTCTACT
TCCCATAAAAGGACCTCTCCTGAGAGGCAAAACCTGTTGCCTCCACCACGGCTTCCCTCTTGGCTCATTCCAAGCTTGGCCAAATTGGGG
AAGTGGGATGGAGGTTGCCCTGCATCCCCCCTCCTCTGCCTGAGTGTGTCTTTGTAATGTCAGCTGGCATCATACAAAGAGCAGGAGAAG
CAAACACCCAGAACTCTTTTGCTGGTCAGAGATTCCCTGAGTGTCTGTCCTCACCCAAGCCTGCTCTGTGTCTGTGTTGTGAAGCTTGAG
ACTCTGGAAAGAAATGGGGAGGGGGGGCAGGGGAAATGTTGCCCTAAGAATGCTTCTCATTCCTCTGTTCTTATTGGGTCCTGTTTTTCG

>In-frame_ENST00000357384_ENST00000262325_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(amino acids)=396AA_start in transcript=390_stop in transcript=1580
MSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQGDLLGDL
LNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGYVAPKAVWLPAVKAK
GLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNI
DVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDMLYQSLKLTNGIWILA

--------------------------------------------------------------
>In-frame_ENST00000357384_ENST00000592545_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(transcript)=2010nt_BP=303nt
TTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGGGGGCGAGGCCGCAGCTAGGG
CGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGCCTTCTCTGAGGCGGCGCTGG
AGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCACCGTAAACACTCGCGTCCCA
TCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGATTCTGATAATCCTGACCTTCGAGACCGGGGCTATATTTATTGGCGCCTTCTCTCA
ACTGACCCTGTTACAGCTAAAGAAGTAGTCTTGTCTGAGAAGCCACTGATCTCTGAGGAGACGGACCTTATTGAGCCAACTCTGCTGGAT
GAGCTAATCTGCCACATTGGTTCTTTGGCCTCTGTGTATCATAAGCCTCCCAATGCTTTTGTGGAAGGAAGTCATGGAATTCATCGTAAA
CACTTGCCAATTCATCATGGGAGCACTGATGCAGGTGACAGCCCTGTTGGCACTACCACTGCAACGAACCTGGAACAGCCTCAGGTTATC
CCCTCTCAAGGTGATCTTCTAGGGGATCTTTTAAACCTTGACCTCGGTCCCCCAGTCAATGTGCCACAGGTGTCCTCCATGCAGATGGGA
GCAGTGGATCTCCTAGGAGGAGGACTAGATAGTCTGCTTGGCAGTGACCTTGGCGGGGGCATTGGAGGAAGTCCGGCAGTGGGACAATCC
TTCATCCCATCATCGGTGCCTGCAACCTTTGCTCCTTCACCTACACCTGCTGTGGTCAGCAGTGGACTGAATGACCTGTTTGAACTCTCC
ACAGGGATAGGCATGGCACCTGGTGGATATGTGGCTCCTAAGGCTGTCTGGCTACCTGCAGTAAAGGCTAAAGGCTTGGAGATTTCCGGA
ACATTTACTCACCGCCAAGGGCACATCTATATGGAAATGAACTTCACCAATAAAGCTCTGCAGCACATGACAGATTTTGCAATCCAGTTT
AACAAAAATAGCTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCT
CTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGC
TGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTCCTTGCAACATGGAAGGATATTCCCAATGAA
AATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACAACAATGTTTATACTATTGCC
AAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACGTATCCAGCCA
GGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAAC
TAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCGGTGCAAGTCAAGAACTCTTAACTGGAAGAAATTGTATTGCTGCGTAGAA
TCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTCTAACCTGTGCTAACATTAGGGCACAACCTGTTGGATAGTTTTAGCTTCC
TGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTCTTGCCACCTGCTGCTGCTATCTGTCCTTACTTGTGGGCTTCTCCATGCT
GTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTAGTTTGGTATTTTGTAATTGAGAGCTCATTTCAAAAGCAGAAAAAGACAA

>In-frame_ENST00000357384_ENST00000592545_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(amino acids)=410AA_start in transcript=390_stop in transcript=1622
MSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQGDLLGDL
LNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLLGSDLGGGIGGSPAVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGY
VAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKM
EPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDML

--------------------------------------------------------------
>In-frame_ENST00000357384_ENST00000538556_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(transcript)=1968nt_BP=303nt
TTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGGGGGCGAGGCCGCAGCTAGGG
CGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGCCTTCTCTGAGGCGGCGCTGG
AGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCACCGTAAACACTCGCGTCCCA
TCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGATTCTGATAATCCTGACCTTCGAGACCGGGGCTATATTTATTGGCGCCTTCTCTCA
ACTGACCCTGTTACAGCTAAAGAAGTAGTCTTGTCTGAGAAGCCACTGATCTCTGAGGAGACGGACCTTATTGAGCCAACTCTGCTGGAT
GAGCTAATCTGCCACATTGGTTCTTTGGCCTCTGTGTATCATAAGCCTCCCAATGCTTTTGTGGAAGGAAGTCATGGAATTCATCGTAAA
CACTTGCCAATTCATCATGGGAGCACTGATGCAGGTGACAGCCCTGTTGGCACTACCACTGCAACGAACCTGGAACAGCCTCAGGTTATC
CCCTCTCAAGGTGATCTTCTAGGGGATCTTTTAAACCTTGACCTCGGTCCCCCAGTCAATGTGCCACAGGTGTCCTCCATGCAGATGGGA
GCAGTGGATCTCCTAGGAGGAGGACTAGATAGTCTGGTGGGACAATCCTTCATCCCATCATCGGTGCCTGCAACCTTTGCTCCTTCACCT
ACACCTGCTGTGGTCAGCAGTGGACTGAATGACCTGTTTGAACTCTCCACAGGGATAGGCATGGCACCTGGTGGATATGTGGCTCCTAAG
GCTGTCTGGCTACCTGCAGTAAAGGCTAAAGGCTTGGAGATTTCCGGAACATTTACTCACCGCCAAGGGCACATCTATATGGAAATGAAC
TTCACCAATAAAGCTCTGCAGCACATGACAGATTTTGCAATCCAGTTTAACAAAAATAGCTTTGGTGTCATCCCCAGCACTCCTCTGGCC
ATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAAT
AACCTCCAGGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAA
ATGGAGCGCCAGGTCTTCCTTGCAACATGGAAGGATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCT
GACACTGTTTCCAGCAAGTTGCAAAACAACAATGTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTG
AAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACGTATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCT
GAAGTCTCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAACTAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCGG
TGCAAGTCAAGAACTCTTAACTGGAAGAAATTGTATTGCTGCGTAGAATCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTCT
AACCTGTGCTAACATTAGGGCACAACCTGTTGGATAGTTTTAGCTTCCTGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTCT
TGCCACCTGCTGCTGCTATCTGTCCTTACTTGTGGGCTTCTCCATGCTGTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTAG

>In-frame_ENST00000357384_ENST00000538556_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(amino acids)=396AA_start in transcript=390_stop in transcript=1580
MSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQGDLLGDL
LNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGYVAPKAVWLPAVKAK
GLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNI
DVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDMLYQSLKLTNGIWILA

--------------------------------------------------------------
>In-frame_ENST00000357384_ENST00000312678_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(transcript)=2299nt_BP=303nt
TTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGGGGGCGAGGCCGCAGCTAGGG
CGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGCCTTCTCTGAGGCGGCGCTGG
AGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCACCGTAAACACTCGCGTCCCA
TCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGATTCTGATAATCCTGACCTTCGAGACCGGGGCTATATTTATTGGCGCCTTCTCTCA
ACTGACCCTGTTACAGCTAAAGAAGTAGTCTTGTCTGAGAAGCCACTGATCTCTGAGGAGACGGACCTTATTGAGCCAACTCTGCTGGAT
GAGCTAATCTGCCACATTGGTTCTTTGGCCTCTGTGTATCATAAGCCTCCCAATGCTTTTGTGGAAGGAAGTCATGGAATTCATCGTAAA
CACTTGCCAATTCATCATGGGAGCACTGATGCAGGTGACAGCCCTGTTGGCACTACCACTGCAACGAACCTGGAACAGCCTCAGGTTATC
CCCTCTCAAGGTGATCTTCTAGGGGATCTTTTAAACCTTGACCTCGGTCCCCCAGTCAATGTGCCACAGGTGTCCTCCATGCAGATGGGA
GCAGTGGATCTCCTAGGAGGAGGACTAGATAGTCTGCTTGGCAGTGACCTTGGCGGGGGCATTGGAGGAAGTCCGGCAGTGGGACAATCC
TTCATCCCATCATCGGTGCCTGCAACCTTTGCTCCTTCACCTACACCTGCTGTGGTCAGCAGTGGACTGAATGACCTGTTTGAACTCTCC
ACAGGGATAGGCATGGCACCTGGTGGATATGTGGCTCCTAAGGCTGTCTGGCTACCTGCAGTAAAGGCTAAAGGCTTGGAGATTTCCGGA
ACATTTACTCACCGCCAAGGGCACATCTATATGGAAATGAACTTCACCAATAAAGCTCTGCAGCACATGACAGATTTTGCAATCCAGTTT
AACAAAAATAGCTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCT
CTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGC
TGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTCCTTGCAACATGGAAGGATATTCCCAATGAA
AATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACAACAATGTTTATACTATTGCC
AAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACGTATCCAGCCA
GGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAAC
TAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCGGTGCAAGTCAAGAACTCTTAACTGGAAGAAATTGTATTGCTGCGTAGAA
TCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTCTAACCTGTGCTAACATTAGGGCACAACCTGTTGGATAGTTTTAGCTTCC
TGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTCTTGCCACCTGCTGCTGCTATCTGTCCTTACTTGTGGGCTTCTCCATGCT
GTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTAGTTTGGTATTTTGTAATTGAGAGCTCATTTCAAAAGCAGAAAAAGACAA
CAAATATTAAAGCAAGGAAAAGTGTAACTGAAACACTGCACTTTACTGTTTTATACTTTTGTACATATGAGAAATCAAGGGATTAGTGCA
ACCAGTAGAAAGCATTGAAATGACTGTCATTAACCACACAGTCCTGGAGGCAGAGATGCAGTTACCTACCCTAGCTTTTGATGGGTTCTC
TTACCTGTAGTAGCCTTATCCCTGGTCATTTGGATTTTCAGTTTGCTTTTTTCTTTTTTTCCCCTCCAAACTCCTTTTCCTTGGCCAAGC

>In-frame_ENST00000357384_ENST00000312678_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(amino acids)=410AA_start in transcript=390_stop in transcript=1622
MSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQGDLLGDL
LNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLLGSDLGGGIGGSPAVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGY
VAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKM
EPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDML

--------------------------------------------------------------
>In-frame_ENST00000357384_ENST00000589344_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(transcript)=1689nt_BP=303nt
TTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGGGGGCGAGGCCGCAGCTAGGG
CGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGCCTTCTCTGAGGCGGCGCTGG
AGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCACCGTAAACACTCGCGTCCCA
TCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGATTCTGATAATCCTGACCTTCGAGACCGGGGCTATATTTATTGGCGCCTTCTCTCA
ACTGACCCTGTTACAGCTAAAGAAGTAGTCTTGTCTGAGAAGCCACTGATCTCTGAGGAGACGGACCTTATTGAGCCAACTCTGCTGGAT
GAGCTAATCTGCCACATTGGTTCTTTGGCCTCTGTGTATCATAAGCCTCCCAATGCTTTTGTGGAAGGAAGTCATGGAATTCATCGTAAA
CACTTGCCAATTCATCATGGGAGCACTGATGCAGGTGACAGCCCTGTTGGCACTACCACTGCAACGAACCTGGAACAGCCTCAGGTTATC
CCCTCTCAAGGTGATCTTCTAGGGGATCTTTTAAACCTTGACCTCGGTCCCCCAGTCAATGTGCCACAGGTGTCCTCCATGCAGATGGGA
GCAGTGGATCTCCTAGGAGGAGGACTAGATAGTCTGCTTGGCAGTGACCTTGGCGGGGGCATTGGAGGAAGTCCGGCAGTGGGACAATCC
TTCATCCCATCATCGGTGCCTGCAACCTTTGCTCCTTCACCTACACCTGCTGTGGTCAGCAGTGGACTGAATGACCTGTTTGAACTCTCC
ACAGGGATAGGCATGGCACCTGGTGGATATGTGGCTCCTAAGGCTGTCTGGCTACCTGCAGTAAAGGCTAAAGGCTTGGAGATTTCCGGA
ACATTTACTCACCGCCAAGGGCACATCTATATGGAAATGAACTTCACCAATAAAGCTCTGCAGCACATGACAGATTTTGCAATCCAGTTT
AACAAAAATAGCTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCT
CTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGC
TGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTCCTTGCAACATGGAAGGATATTCCCAATGAA
AATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACAACAATGTTTATACTATTGCC
AAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACGTATCCAGCCA
GGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAAC

>In-frame_ENST00000357384_ENST00000589344_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(amino acids)=410AA_start in transcript=390_stop in transcript=1622
MSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQGDLLGDL
LNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLLGSDLGGGIGGSPAVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGY
VAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKM
EPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDML

--------------------------------------------------------------
>In-frame_ENST00000357384_ENST00000537622_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(transcript)=2013nt_BP=303nt
TTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGGGGGCGAGGCCGCAGCTAGGG
CGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGCCTTCTCTGAGGCGGCGCTGG
AGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCACCGTAAACACTCGCGTCCCA
TCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGATTCTGATAATCCTGACCTTCGAGACCGGGGCTATATTTATTGGCGCCTTCTCTCA
ACTGACCCTGTTACAGCTAAAGAAGTAGTCTTGTCTGAGAAGCCACTGATCTCTGAGGAGACGGACCTTATTGAGCCAACTCTGCTGGAT
GAGCTAATCTGCCACATTGGTTCTTTGGCCTCTGTGTATCATAAGCCTCCCAATGCTTTTGTGGAAGGAAGTCATGGAATTCATCGTAAA
CACTTGCCAATTCATCATGGGAGCACTGATGCAGGTGACAGCCCTGTTGGCACTACCACTGCAACGAACCTGGAACAGCCTCAGGTTATC
CCCTCTCAAGGTGATCTTCTAGGGGATCTTTTAAACCTTGACCTCGGTCCCCCAGTCAATGTGCCACAGGTGTCCTCCATGCAGATGGGA
GCAGTGGATCTCCTAGGAGGAGGACTAGATAGTCTGCTTGGCAGTGACCTTGGCGGGGGCATTGGAGGAAGTCCGGCAGTGGGACAATCC
TTCATCCCATCATCGGTGCCTGCAACCTTTGCTCCTTCACCTACACCTGCTGTGGTCAGCAGTGGACTGAATGACCTGTTTGAACTCTCC
ACAGGGATAGGCATGGCACCTGGTGGATATGTGGCTCCTAAGGCTGTCTGGCTACCTGCAGTAAAGGCTAAAGGCTTGGAGATTTCCGGA
ACATTTACTCACCGCCAAGGGCACATCTATATGGAAATGAACTTCACCAATAAAGCTCTGCAGCACATGACAGATTTTGCAATCCAGTTT
AACAAAAATAGCTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCT
CTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGC
TGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTCCTTGCAACATGGAAGGATATTCCCAATGAA
AATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACAACAATGTTTATACTATTGCC
AAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACGTATCCAGCCA
GGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAAC
TAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCGGTGCAAGTCAAGAACTCTTAACTGGAAGAAATTGTATTGCTGCGTAGAA
TCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTCTAACCTGTGCTAACATTAGGGCACAACCTGTTGGATAGTTTTAGCTTCC
TGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTCTTGCCACCTGCTGCTGCTATCTGTCCTTACTTGTGGGCTTCTCCATGCT
GTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTAGTTTGGTATTTTGTAATTGAGAGCTCATTTCAAAAGCAGAAAAAGACAA

>In-frame_ENST00000357384_ENST00000537622_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(amino acids)=410AA_start in transcript=390_stop in transcript=1622
MSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQGDLLGDL
LNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLLGSDLGGGIGGSPAVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGY
VAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKM
EPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDML

--------------------------------------------------------------
>In-frame_ENST00000319040_ENST00000262325_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(transcript)=4299nt_BP=303nt
TTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGGGGGCGAGGCCGCAGCTAGGG
CGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGCCTTCTCTGAGGCGGCGCTGG
AGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCACCGTAAACACTCGCGTCCCA
TCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGATTCTGATAATCCTGACCTTCGAGACCGGGGCTATATTTATTGGCGCCTTCTCTCA
ACTGACCCTGTTACAGCTAAAGAAGTAGTCTTGTCTGAGAAGCCACTGATCTCTGAGGAGACGGACCTTATTGAGCCAACTCTGCTGGAT
GAGCTAATCTGCCACATTGGTTCTTTGGCCTCTGTGTATCATAAGCCTCCCAATGCTTTTGTGGAAGGAAGTCATGGAATTCATCGTAAA
CACTTGCCAATTCATCATGGGAGCACTGATGCAGGTGACAGCCCTGTTGGCACTACCACTGCAACGAACCTGGAACAGCCTCAGGTTATC
CCCTCTCAAGGTGATCTTCTAGGGGATCTTTTAAACCTTGACCTCGGTCCCCCAGTCAATGTGCCACAGGTGTCCTCCATGCAGATGGGA
GCAGTGGATCTCCTAGGAGGAGGACTAGATAGTCTGGTGGGACAATCCTTCATCCCATCATCGGTGCCTGCAACCTTTGCTCCTTCACCT
ACACCTGCTGTGGTCAGCAGTGGACTGAATGACCTGTTTGAACTCTCCACAGGGATAGGCATGGCACCTGGTGGATATGTGGCTCCTAAG
GCTGTCTGGCTACCTGCAGTAAAGGCTAAAGGCTTGGAGATTTCCGGAACATTTACTCACCGCCAAGGGCACATCTATATGGAAATGAAC
TTCACCAATAAAGCTCTGCAGCACATGACAGATTTTGCAATCCAGTTTAACAAAAATAGCTTTGGTGTCATCCCCAGCACTCCTCTGGCC
ATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAAT
AACCTCCAGGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAA
ATGGAGCGCCAGGTCTTCCTTGCAACATGGAAGGATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCT
GACACTGTTTCCAGCAAGTTGCAAAACAACAATGTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTG
AAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACGTATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCT
GAAGTCTCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAACTAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCGG
TGCAAGTCAAGAACTCTTAACTGGAAGAAATTGTATTGCTGCGTAGAATCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTCT
AACCTGTGCTAACATTAGGGCACAACCTGTTGGATAGTTTTAGCTTCCTGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTCT
TGCCACCTGCTGCTGCTATCTGTCCTTACTTGTGGGCTTCTCCATGCTGTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTAG
TTTGGTATTTTGTAATTGAGAGCTCATTTCAAAAGCAGAAAAAGACAACAAATATTAAAGCAAGGAAAAGTGTAACTGAAACACTGCACT
TTACTGTTTTATACTTTTGTACATATGAGAAATCAAGGGATTAGTGCAACCAGTAGAAAGCATTGAAATGACTGTCATTAACCACACAGT
CCTGGAGGCAGAGATGCAGTTACCTACCCTAGCTTTTGATGGGTTCTCTTACCTGTAGTAGCCTTATCCCTGGTCATTTGGATTTTCAGT
TTGCTTTTTTCTTTTTTTCCCCTCCAAACTCCTTTTCCTTGGCCAAGCCTTCATGCTTCCCCCTTTCCATATTATAATCTCATTTGATTG
CTCTGCAGTTGGGAACGGTGATCTTCTTGAATGATGTTTCAGTGTGCAAAAACTATAGAGCCTGTCAGCACCAAAGCTGACAGAAGTTAT
ACCTTACTCCTTTCCTTTCCCCTGAACAAACCTGCTAATCCCACTAATTCAGGAATTTGAGTAGAGATGGGGAACAAGAACCCAGATGCT
GTCCCCTCACCCCCTCTCCTGTATTTCTCAGGTCCAGTTCAAATCTAAAATTCTACTTTTAGAGTTGAAACAGAGTAATAACTTATCTAA
CCCTCTTTTCCTACAAAGGAGAAAGATAAAAGGCACAAAGGTTACCGCCAAGGCCCGTCAGCTGTGTAGTGGCAAAGCCGAGACCGAGTC
TCCTAAGTCCCCGTCAGTGTGGTTTTCACCACAGGACTGTCTCTTGTCGTTTTCCCCTAATGCCTTCTCCTGCCTTTTCTGTGCCTAGTT
TTTGGCTCTTCACATATTCCATATTGATTTTGACGCTCTGTATATTGGCATCAGGTGGCAGCTGAATATCTTTTGAATTACTCGAAGGTA
AAGCCAGATGCCAGAATGAAGGTGTAGCCAGTGTTTCCCATATGCCCCTGGAGCCCCACTTATTGAGGCCAGCAGAATAGGTGCAGAGAT
GAAGTGAGCTTAGAGATGTTGCAAATGCTCTTTATCCCTTCAGCTCTCTGATCTGCTCTTTCTTCATGATACTTAGTCTGCAGGGCATAT
TAAGATCATCCCAGAGGTTCAGGCAGTTCCTGTCATCTCTGAAAAGACTGGGGGATATGAAATCTTCCCCCTACCCCACTTAATGCGTTG
GATATGATTTTTCAAAGAATGCTTCATGCCCAAAATACCAGCCTGTTTAGCAGTGTTACACTGTTTGATCTGCGGGCACTTGTTGCATTG
CCTGGCACCCAATATTCAGGGTCCATGACTAAGACTGGTCTTCTCAGATGCCCTGCTTAAATCAGGGGCACTTCAGGCTCCACAGGCGTC
ATGTTGGACTGAGACCTAACTCACTGGACTCAGAGGAGGAATCGTGGAAAACAAGAGCAAAACTACCCCACACCCCTATTTCATGTCTGA
AATAACCCTGTTTCATACCAGTTGCAAAGCTTGTGGGGAGCGGTCCCACAAAGCACTTTCTTAAACCTTGAGAATCTCCAAGAGAAAAAT
ATTTGGGGAAGGAGGGAGGAAATATGTCCCTTGCACACCACCCCTGAAGCACATGGCAGTAGGAAACAGCATAGGATTGTATGTGGGAGG
TGGATAGGTCGGTGATGTGTGGAGCGGAAAAGCAGGTTGGTAAAGTTCCCTTCTTGGGACTTATTCCTGGAGTCAGTGGATACAAGTAGT
GCAGAAGGTTCACACTGCAAATAGTGTTCTCATCTCAAAGCAAACTATCATTCCAGAAGGAAAAGTGTGTCAGGGCAAGCAGACAACACA
ATTTCCTATCAGAATATGTCCCTCAACCCCCGAAACAAGGCTTCTCTCAGCCTCCCCACCAGTGATGGATAACAGCTCCTATTCTCAGCT
GACCTGACTGAGCCAACCCATGAACTCTTCACTCCTTGGGGAAGCCACCTCCCATCACACCCCTGAGCAGAGTTAGGGAGGAATTCTACT
TCCCATAAAAGGACCTCTCCTGAGAGGCAAAACCTGTTGCCTCCACCACGGCTTCCCTCTTGGCTCATTCCAAGCTTGGCCAAATTGGGG
AAGTGGGATGGAGGTTGCCCTGCATCCCCCCTCCTCTGCCTGAGTGTGTCTTTGTAATGTCAGCTGGCATCATACAAAGAGCAGGAGAAG
CAAACACCCAGAACTCTTTTGCTGGTCAGAGATTCCCTGAGTGTCTGTCCTCACCCAAGCCTGCTCTGTGTCTGTGTTGTGAAGCTTGAG
ACTCTGGAAAGAAATGGGGAGGGGGGGCAGGGGAAATGTTGCCCTAAGAATGCTTCTCATTCCTCTGTTCTTATTGGGTCCTGTTTTTCG

>In-frame_ENST00000319040_ENST00000262325_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(amino acids)=396AA_start in transcript=390_stop in transcript=1580
MSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQGDLLGDL
LNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGYVAPKAVWLPAVKAK
GLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNI
DVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDMLYQSLKLTNGIWILA

--------------------------------------------------------------
>In-frame_ENST00000319040_ENST00000592545_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(transcript)=2010nt_BP=303nt
TTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGGGGGCGAGGCCGCAGCTAGGG
CGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGCCTTCTCTGAGGCGGCGCTGG
AGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCACCGTAAACACTCGCGTCCCA
TCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGATTCTGATAATCCTGACCTTCGAGACCGGGGCTATATTTATTGGCGCCTTCTCTCA
ACTGACCCTGTTACAGCTAAAGAAGTAGTCTTGTCTGAGAAGCCACTGATCTCTGAGGAGACGGACCTTATTGAGCCAACTCTGCTGGAT
GAGCTAATCTGCCACATTGGTTCTTTGGCCTCTGTGTATCATAAGCCTCCCAATGCTTTTGTGGAAGGAAGTCATGGAATTCATCGTAAA
CACTTGCCAATTCATCATGGGAGCACTGATGCAGGTGACAGCCCTGTTGGCACTACCACTGCAACGAACCTGGAACAGCCTCAGGTTATC
CCCTCTCAAGGTGATCTTCTAGGGGATCTTTTAAACCTTGACCTCGGTCCCCCAGTCAATGTGCCACAGGTGTCCTCCATGCAGATGGGA
GCAGTGGATCTCCTAGGAGGAGGACTAGATAGTCTGCTTGGCAGTGACCTTGGCGGGGGCATTGGAGGAAGTCCGGCAGTGGGACAATCC
TTCATCCCATCATCGGTGCCTGCAACCTTTGCTCCTTCACCTACACCTGCTGTGGTCAGCAGTGGACTGAATGACCTGTTTGAACTCTCC
ACAGGGATAGGCATGGCACCTGGTGGATATGTGGCTCCTAAGGCTGTCTGGCTACCTGCAGTAAAGGCTAAAGGCTTGGAGATTTCCGGA
ACATTTACTCACCGCCAAGGGCACATCTATATGGAAATGAACTTCACCAATAAAGCTCTGCAGCACATGACAGATTTTGCAATCCAGTTT
AACAAAAATAGCTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCT
CTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGC
TGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTCCTTGCAACATGGAAGGATATTCCCAATGAA
AATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACAACAATGTTTATACTATTGCC
AAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACGTATCCAGCCA
GGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAAC
TAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCGGTGCAAGTCAAGAACTCTTAACTGGAAGAAATTGTATTGCTGCGTAGAA
TCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTCTAACCTGTGCTAACATTAGGGCACAACCTGTTGGATAGTTTTAGCTTCC
TGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTCTTGCCACCTGCTGCTGCTATCTGTCCTTACTTGTGGGCTTCTCCATGCT
GTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTAGTTTGGTATTTTGTAATTGAGAGCTCATTTCAAAAGCAGAAAAAGACAA

>In-frame_ENST00000319040_ENST00000592545_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(amino acids)=410AA_start in transcript=390_stop in transcript=1622
MSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQGDLLGDL
LNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLLGSDLGGGIGGSPAVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGY
VAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKM
EPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDML

--------------------------------------------------------------
>In-frame_ENST00000319040_ENST00000538556_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(transcript)=1968nt_BP=303nt
TTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGGGGGCGAGGCCGCAGCTAGGG
CGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGCCTTCTCTGAGGCGGCGCTGG
AGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCACCGTAAACACTCGCGTCCCA
TCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGATTCTGATAATCCTGACCTTCGAGACCGGGGCTATATTTATTGGCGCCTTCTCTCA
ACTGACCCTGTTACAGCTAAAGAAGTAGTCTTGTCTGAGAAGCCACTGATCTCTGAGGAGACGGACCTTATTGAGCCAACTCTGCTGGAT
GAGCTAATCTGCCACATTGGTTCTTTGGCCTCTGTGTATCATAAGCCTCCCAATGCTTTTGTGGAAGGAAGTCATGGAATTCATCGTAAA
CACTTGCCAATTCATCATGGGAGCACTGATGCAGGTGACAGCCCTGTTGGCACTACCACTGCAACGAACCTGGAACAGCCTCAGGTTATC
CCCTCTCAAGGTGATCTTCTAGGGGATCTTTTAAACCTTGACCTCGGTCCCCCAGTCAATGTGCCACAGGTGTCCTCCATGCAGATGGGA
GCAGTGGATCTCCTAGGAGGAGGACTAGATAGTCTGGTGGGACAATCCTTCATCCCATCATCGGTGCCTGCAACCTTTGCTCCTTCACCT
ACACCTGCTGTGGTCAGCAGTGGACTGAATGACCTGTTTGAACTCTCCACAGGGATAGGCATGGCACCTGGTGGATATGTGGCTCCTAAG
GCTGTCTGGCTACCTGCAGTAAAGGCTAAAGGCTTGGAGATTTCCGGAACATTTACTCACCGCCAAGGGCACATCTATATGGAAATGAAC
TTCACCAATAAAGCTCTGCAGCACATGACAGATTTTGCAATCCAGTTTAACAAAAATAGCTTTGGTGTCATCCCCAGCACTCCTCTGGCC
ATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAAT
AACCTCCAGGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAA
ATGGAGCGCCAGGTCTTCCTTGCAACATGGAAGGATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCT
GACACTGTTTCCAGCAAGTTGCAAAACAACAATGTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTG
AAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACGTATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCT
GAAGTCTCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAACTAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCGG
TGCAAGTCAAGAACTCTTAACTGGAAGAAATTGTATTGCTGCGTAGAATCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTCT
AACCTGTGCTAACATTAGGGCACAACCTGTTGGATAGTTTTAGCTTCCTGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTCT
TGCCACCTGCTGCTGCTATCTGTCCTTACTTGTGGGCTTCTCCATGCTGTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTAG

>In-frame_ENST00000319040_ENST00000538556_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(amino acids)=396AA_start in transcript=390_stop in transcript=1580
MSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQGDLLGDL
LNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGYVAPKAVWLPAVKAK
GLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNI
DVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDMLYQSLKLTNGIWILA

--------------------------------------------------------------
>In-frame_ENST00000319040_ENST00000312678_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(transcript)=2299nt_BP=303nt
TTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGGGGGCGAGGCCGCAGCTAGGG
CGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGCCTTCTCTGAGGCGGCGCTGG
AGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCACCGTAAACACTCGCGTCCCA
TCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGATTCTGATAATCCTGACCTTCGAGACCGGGGCTATATTTATTGGCGCCTTCTCTCA
ACTGACCCTGTTACAGCTAAAGAAGTAGTCTTGTCTGAGAAGCCACTGATCTCTGAGGAGACGGACCTTATTGAGCCAACTCTGCTGGAT
GAGCTAATCTGCCACATTGGTTCTTTGGCCTCTGTGTATCATAAGCCTCCCAATGCTTTTGTGGAAGGAAGTCATGGAATTCATCGTAAA
CACTTGCCAATTCATCATGGGAGCACTGATGCAGGTGACAGCCCTGTTGGCACTACCACTGCAACGAACCTGGAACAGCCTCAGGTTATC
CCCTCTCAAGGTGATCTTCTAGGGGATCTTTTAAACCTTGACCTCGGTCCCCCAGTCAATGTGCCACAGGTGTCCTCCATGCAGATGGGA
GCAGTGGATCTCCTAGGAGGAGGACTAGATAGTCTGCTTGGCAGTGACCTTGGCGGGGGCATTGGAGGAAGTCCGGCAGTGGGACAATCC
TTCATCCCATCATCGGTGCCTGCAACCTTTGCTCCTTCACCTACACCTGCTGTGGTCAGCAGTGGACTGAATGACCTGTTTGAACTCTCC
ACAGGGATAGGCATGGCACCTGGTGGATATGTGGCTCCTAAGGCTGTCTGGCTACCTGCAGTAAAGGCTAAAGGCTTGGAGATTTCCGGA
ACATTTACTCACCGCCAAGGGCACATCTATATGGAAATGAACTTCACCAATAAAGCTCTGCAGCACATGACAGATTTTGCAATCCAGTTT
AACAAAAATAGCTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCT
CTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGC
TGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTCCTTGCAACATGGAAGGATATTCCCAATGAA
AATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACAACAATGTTTATACTATTGCC
AAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACGTATCCAGCCA
GGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAAC
TAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCGGTGCAAGTCAAGAACTCTTAACTGGAAGAAATTGTATTGCTGCGTAGAA
TCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTCTAACCTGTGCTAACATTAGGGCACAACCTGTTGGATAGTTTTAGCTTCC
TGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTCTTGCCACCTGCTGCTGCTATCTGTCCTTACTTGTGGGCTTCTCCATGCT
GTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTAGTTTGGTATTTTGTAATTGAGAGCTCATTTCAAAAGCAGAAAAAGACAA
CAAATATTAAAGCAAGGAAAAGTGTAACTGAAACACTGCACTTTACTGTTTTATACTTTTGTACATATGAGAAATCAAGGGATTAGTGCA
ACCAGTAGAAAGCATTGAAATGACTGTCATTAACCACACAGTCCTGGAGGCAGAGATGCAGTTACCTACCCTAGCTTTTGATGGGTTCTC
TTACCTGTAGTAGCCTTATCCCTGGTCATTTGGATTTTCAGTTTGCTTTTTTCTTTTTTTCCCCTCCAAACTCCTTTTCCTTGGCCAAGC

>In-frame_ENST00000319040_ENST00000312678_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(amino acids)=410AA_start in transcript=390_stop in transcript=1622
MSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQGDLLGDL
LNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLLGSDLGGGIGGSPAVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGY
VAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKM
EPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDML

--------------------------------------------------------------
>In-frame_ENST00000319040_ENST00000589344_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(transcript)=1689nt_BP=303nt
TTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGGGGGCGAGGCCGCAGCTAGGG
CGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGCCTTCTCTGAGGCGGCGCTGG
AGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCACCGTAAACACTCGCGTCCCA
TCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGATTCTGATAATCCTGACCTTCGAGACCGGGGCTATATTTATTGGCGCCTTCTCTCA
ACTGACCCTGTTACAGCTAAAGAAGTAGTCTTGTCTGAGAAGCCACTGATCTCTGAGGAGACGGACCTTATTGAGCCAACTCTGCTGGAT
GAGCTAATCTGCCACATTGGTTCTTTGGCCTCTGTGTATCATAAGCCTCCCAATGCTTTTGTGGAAGGAAGTCATGGAATTCATCGTAAA
CACTTGCCAATTCATCATGGGAGCACTGATGCAGGTGACAGCCCTGTTGGCACTACCACTGCAACGAACCTGGAACAGCCTCAGGTTATC
CCCTCTCAAGGTGATCTTCTAGGGGATCTTTTAAACCTTGACCTCGGTCCCCCAGTCAATGTGCCACAGGTGTCCTCCATGCAGATGGGA
GCAGTGGATCTCCTAGGAGGAGGACTAGATAGTCTGCTTGGCAGTGACCTTGGCGGGGGCATTGGAGGAAGTCCGGCAGTGGGACAATCC
TTCATCCCATCATCGGTGCCTGCAACCTTTGCTCCTTCACCTACACCTGCTGTGGTCAGCAGTGGACTGAATGACCTGTTTGAACTCTCC
ACAGGGATAGGCATGGCACCTGGTGGATATGTGGCTCCTAAGGCTGTCTGGCTACCTGCAGTAAAGGCTAAAGGCTTGGAGATTTCCGGA
ACATTTACTCACCGCCAAGGGCACATCTATATGGAAATGAACTTCACCAATAAAGCTCTGCAGCACATGACAGATTTTGCAATCCAGTTT
AACAAAAATAGCTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCT
CTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGC
TGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTCCTTGCAACATGGAAGGATATTCCCAATGAA
AATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACAACAATGTTTATACTATTGCC
AAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACGTATCCAGCCA
GGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAAC

>In-frame_ENST00000319040_ENST00000589344_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(amino acids)=410AA_start in transcript=390_stop in transcript=1622
MSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQGDLLGDL
LNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLLGSDLGGGIGGSPAVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGY
VAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKM
EPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDML

--------------------------------------------------------------
>In-frame_ENST00000319040_ENST00000537622_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(transcript)=2013nt_BP=303nt
TTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGGGGGCGAGGCCGCAGCTAGGG
CGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGCCTTCTCTGAGGCGGCGCTGG
AGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCACCGTAAACACTCGCGTCCCA
TCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGATTCTGATAATCCTGACCTTCGAGACCGGGGCTATATTTATTGGCGCCTTCTCTCA
ACTGACCCTGTTACAGCTAAAGAAGTAGTCTTGTCTGAGAAGCCACTGATCTCTGAGGAGACGGACCTTATTGAGCCAACTCTGCTGGAT
GAGCTAATCTGCCACATTGGTTCTTTGGCCTCTGTGTATCATAAGCCTCCCAATGCTTTTGTGGAAGGAAGTCATGGAATTCATCGTAAA
CACTTGCCAATTCATCATGGGAGCACTGATGCAGGTGACAGCCCTGTTGGCACTACCACTGCAACGAACCTGGAACAGCCTCAGGTTATC
CCCTCTCAAGGTGATCTTCTAGGGGATCTTTTAAACCTTGACCTCGGTCCCCCAGTCAATGTGCCACAGGTGTCCTCCATGCAGATGGGA
GCAGTGGATCTCCTAGGAGGAGGACTAGATAGTCTGCTTGGCAGTGACCTTGGCGGGGGCATTGGAGGAAGTCCGGCAGTGGGACAATCC
TTCATCCCATCATCGGTGCCTGCAACCTTTGCTCCTTCACCTACACCTGCTGTGGTCAGCAGTGGACTGAATGACCTGTTTGAACTCTCC
ACAGGGATAGGCATGGCACCTGGTGGATATGTGGCTCCTAAGGCTGTCTGGCTACCTGCAGTAAAGGCTAAAGGCTTGGAGATTTCCGGA
ACATTTACTCACCGCCAAGGGCACATCTATATGGAAATGAACTTCACCAATAAAGCTCTGCAGCACATGACAGATTTTGCAATCCAGTTT
AACAAAAATAGCTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCT
CTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGC
TGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTCCTTGCAACATGGAAGGATATTCCCAATGAA
AATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACAACAATGTTTATACTATTGCC
AAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACGTATCCAGCCA
GGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAAC
TAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCGGTGCAAGTCAAGAACTCTTAACTGGAAGAAATTGTATTGCTGCGTAGAA
TCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTCTAACCTGTGCTAACATTAGGGCACAACCTGTTGGATAGTTTTAGCTTCC
TGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTCTTGCCACCTGCTGCTGCTATCTGTCCTTACTTGTGGGCTTCTCCATGCT
GTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTAGTTTGGTATTTTGTAATTGAGAGCTCATTTCAAAAGCAGAAAAAGACAA

>In-frame_ENST00000319040_ENST00000537622_TCGA-06-5415-01A_RPRD1A_chr18_33647217_-_AP2B1_chr17_33977549_length(amino acids)=410AA_start in transcript=390_stop in transcript=1622
MSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQGDLLGDL
LNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLLGSDLGGGIGGSPAVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGY
VAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKM
EPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDML

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for RPRD1A-AP2B1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneAP2B1chr18:33647217chr17:33977549ENST000002623251121841_937512.0938.0ARRB1
TgeneAP2B1chr18:33647217chr17:33977549ENST000003126781122841_937512.0952.0ARRB1
TgeneAP2B1chr18:33647217chr17:33977549ENST000005376221122841_937512.0952.0ARRB1
TgeneAP2B1chr18:33647217chr17:33977549ENST000005385561222841_937455.0881.0ARRB1
TgeneAP2B1chr18:33647217chr17:33977549ENST000005893441122841_937512.0952.0ARRB1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for RPRD1A-AP2B1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for RPRD1A-AP2B1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneAP2B1C0086132Depressive Symptoms1PSYGENET