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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:RPRD2-VPS45 (FusionGDB2 ID:76795)

Fusion Gene Summary for RPRD2-VPS45

check button Fusion gene summary
Fusion gene informationFusion gene name: RPRD2-VPS45
Fusion gene ID: 76795
HgeneTgene
Gene symbol

RPRD2

VPS45

Gene ID

23248

11311

Gene nameregulation of nuclear pre-mRNA domain containing 2vacuolar protein sorting 45 homolog
SynonymsHSPC099|KIAA0460H1|H1VPS45|SCN5|VPS45A|VPS45B|VPS54A|VSP45|VSP45A
Cytomap

1q21.2

1q21.2

Type of geneprotein-codingprotein-coding
Descriptionregulation of nuclear pre-mRNA domain-containing protein 2vacuolar protein sorting-associated protein 45leucocyte vacuolar protein sorting 45vacuolar protein sorting 45A
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000492220, ENST00000401000, 
ENST00000539519, ENST00000369067, 
ENST00000369068, 		ENST00000369130, 
ENST00000369128, ENST00000535106, 
ENST00000484306, 
Fusion gene scores* DoF score11 X 8 X 8=7048 X 7 X 6=336
# samples 1310
** MAII scorelog2(13/704*10)=-2.43706380560884
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/336*10)=-1.74846123300404
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RPRD2 [Title/Abstract] AND VPS45 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRPRD2(150418877)-VPS45(150053424), # samples:2
VPS45(150049857)-RPRD2(150429764), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across RPRD2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across VPS45 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A7-A13D-01ARPRD2chr1

150418877

+VPS45chr1

150053424

+
ChimerDB4BRCATCGA-A7-A13D-01ARPRD2chr1

150418877

-VPS45chr1

150053424

+


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Fusion Gene ORF analysis for RPRD2-VPS45

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000492220ENST00000369130RPRD2chr1

150418877

+VPS45chr1

150053424

+
3UTR-3CDSENST00000492220ENST00000369128RPRD2chr1

150418877

+VPS45chr1

150053424

+
3UTR-3CDSENST00000492220ENST00000535106RPRD2chr1

150418877

+VPS45chr1

150053424

+
3UTR-intronENST00000492220ENST00000484306RPRD2chr1

150418877

+VPS45chr1

150053424

+
In-frameENST00000401000ENST00000369130RPRD2chr1

150418877

+VPS45chr1

150053424

+
In-frameENST00000401000ENST00000369128RPRD2chr1

150418877

+VPS45chr1

150053424

+
In-frameENST00000401000ENST00000535106RPRD2chr1

150418877

+VPS45chr1

150053424

+
5CDS-intronENST00000401000ENST00000484306RPRD2chr1

150418877

+VPS45chr1

150053424

+
In-frameENST00000539519ENST00000369130RPRD2chr1

150418877

+VPS45chr1

150053424

+
In-frameENST00000539519ENST00000369128RPRD2chr1

150418877

+VPS45chr1

150053424

+
In-frameENST00000539519ENST00000535106RPRD2chr1

150418877

+VPS45chr1

150053424

+
5CDS-intronENST00000539519ENST00000484306RPRD2chr1

150418877

+VPS45chr1

150053424

+
intron-3CDSENST00000369067ENST00000369130RPRD2chr1

150418877

+VPS45chr1

150053424

+
intron-3CDSENST00000369067ENST00000369128RPRD2chr1

150418877

+VPS45chr1

150053424

+
intron-3CDSENST00000369067ENST00000535106RPRD2chr1

150418877

+VPS45chr1

150053424

+
intron-intronENST00000369067ENST00000484306RPRD2chr1

150418877

+VPS45chr1

150053424

+
In-frameENST00000369068ENST00000369130RPRD2chr1

150418877

+VPS45chr1

150053424

+
In-frameENST00000369068ENST00000369128RPRD2chr1

150418877

+VPS45chr1

150053424

+
In-frameENST00000369068ENST00000535106RPRD2chr1

150418877

+VPS45chr1

150053424

+
5CDS-intronENST00000369068ENST00000484306RPRD2chr1

150418877

+VPS45chr1

150053424

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000401000RPRD2chr1150418877+ENST00000369130VPS45chr1150053424+2414857651882605
ENST00000401000RPRD2chr1150418877+ENST00000369128VPS45chr1150053424+2469857652101678
ENST00000401000RPRD2chr1150418877+ENST00000535106VPS45chr1150053424+2040857651681538
ENST00000539519RPRD2chr1150418877+ENST00000369130VPS45chr1150053424+2371814221839605
ENST00000539519RPRD2chr1150418877+ENST00000369128VPS45chr1150053424+2426814222058678
ENST00000539519RPRD2chr1150418877+ENST00000535106VPS45chr1150053424+1997814221638538
ENST00000369068RPRD2chr1150418877+ENST00000369130VPS45chr1150053424+243187441899631
ENST00000369068RPRD2chr1150418877+ENST00000369128VPS45chr1150053424+248687442118704
ENST00000369068RPRD2chr1150418877+ENST00000535106VPS45chr1150053424+205787441698564

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000401000ENST00000369130RPRD2chr1150418877+VPS45chr1150053424+0.0036770850.996323
ENST00000401000ENST00000369128RPRD2chr1150418877+VPS45chr1150053424+0.0046415310.9953584
ENST00000401000ENST00000535106RPRD2chr1150418877+VPS45chr1150053424+0.0055372360.9944628
ENST00000539519ENST00000369130RPRD2chr1150418877+VPS45chr1150053424+0.0031902680.99680966
ENST00000539519ENST00000369128RPRD2chr1150418877+VPS45chr1150053424+0.0038786690.99612135
ENST00000539519ENST00000535106RPRD2chr1150418877+VPS45chr1150053424+0.0053699370.9946301
ENST00000369068ENST00000369130RPRD2chr1150418877+VPS45chr1150053424+0.0034535090.99654645
ENST00000369068ENST00000369128RPRD2chr1150418877+VPS45chr1150053424+0.0032941360.99670583
ENST00000369068ENST00000535106RPRD2chr1150418877+VPS45chr1150053424+0.0058520990.9941479

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Fusion Genomic Features for RPRD2-VPS45


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
RPRD2chr1150418877+VPS45chr1150053423+3.06E-060.9999969
RPRD2chr1150418877+VPS45chr1150053423+3.06E-060.9999969

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for RPRD2-VPS45


check button Go to

FGviewer for the breakpoints of chr1:150418877-chr1:150053424

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRPRD2chr1:150418877chr1:150053424ENST00000369068+7114_19290.01462.0Compositional biasNote=Gly/Ser-rich
HgeneRPRD2chr1:150418877chr1:150053424ENST00000401000+6104_19264.01436.0Compositional biasNote=Gly/Ser-rich
HgeneRPRD2chr1:150418877chr1:150053424ENST00000369068+71119_149290.01462.0DomainCID
HgeneRPRD2chr1:150418877chr1:150053424ENST00000401000+61019_149264.01436.0DomainCID

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRPRD2chr1:150418877chr1:150053424ENST00000369067+131054_10570153.0Compositional biasNote=Poly-Gln
HgeneRPRD2chr1:150418877chr1:150053424ENST00000369067+131152_11580153.0Compositional biasNote=Poly-Gly
HgeneRPRD2chr1:150418877chr1:150053424ENST00000369067+131195_14590153.0Compositional biasNote=Pro-rich
HgeneRPRD2chr1:150418877chr1:150053424ENST00000369067+13457_9500153.0Compositional biasNote=Ser-rich
HgeneRPRD2chr1:150418877chr1:150053424ENST00000369067+134_190153.0Compositional biasNote=Gly/Ser-rich
HgeneRPRD2chr1:150418877chr1:150053424ENST00000369068+7111054_1057290.01462.0Compositional biasNote=Poly-Gln
HgeneRPRD2chr1:150418877chr1:150053424ENST00000369068+7111152_1158290.01462.0Compositional biasNote=Poly-Gly
HgeneRPRD2chr1:150418877chr1:150053424ENST00000369068+7111195_1459290.01462.0Compositional biasNote=Pro-rich
HgeneRPRD2chr1:150418877chr1:150053424ENST00000369068+711457_950290.01462.0Compositional biasNote=Ser-rich
HgeneRPRD2chr1:150418877chr1:150053424ENST00000401000+6101054_1057264.01436.0Compositional biasNote=Poly-Gln
HgeneRPRD2chr1:150418877chr1:150053424ENST00000401000+6101152_1158264.01436.0Compositional biasNote=Poly-Gly
HgeneRPRD2chr1:150418877chr1:150053424ENST00000401000+6101195_1459264.01436.0Compositional biasNote=Pro-rich
HgeneRPRD2chr1:150418877chr1:150053424ENST00000401000+610457_950264.01436.0Compositional biasNote=Ser-rich
HgeneRPRD2chr1:150418877chr1:150053424ENST00000369067+1319_1490153.0DomainCID


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Fusion Gene Sequence for RPRD2-VPS45


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000401000_ENST00000369130_TCGA-A7-A13D-01A_RPRD2_chr1_150418877_+_VPS45_chr1_150053424_length(transcript)=2414nt_BP=857nt
CCGCTCCCGCCGCCGCCGCCGCCGCCGCCGCCAGAGGAGCAGCAGCGCTTGTGCAAACCGGGAAGATGGCGGCCGGCGGCGGCGGAGGCA
GCAGTAAGGCCTCCTCCTCGTCGGCCTCTTCGGCAGGGGCTCTGGAGTCCTCGTTGGATCGAAAATTCCAGTCGGTAACCAACACCATGG
AGTCCATTCAAGGCTTGTCGTCTTGGTGTATAGAGAACAAAAAACACCACAGTACTATCGTCTATCATTGGATGAAGTGGCTCCGGAGAT
CTGCATATCCCCACCGTTTGAATCTCTTTTACCTTGCCAATGATGTCATACAGAACTGTAAAAGGAAAAATGCAATCATATTCCGTGAAT
CATTTGCTGATGTACTTCCTGAAGCAGCTGCTCTAGTGAAGGATCCATCTGTCTCTAAGTCTGTAGAACGAATCTTTAAAATCTGGGAAG
ATAGAAATGTATACCCAGAAGAAATGATTGTGGCATTGAGAGAAGCTTTGACATCTACAAATCCAAAAGCTGCTCTCAAGTCTAAGATAG
TTGCTGAATTTCGATCTCAGGCCCTAATTGAAGAGCTGTTGCTATACAAGCGCTCAGAAGATCAGATAGAACTGAAGGAAAAGCAGTTGT
CAACTATGAGGGTGGATGTGTGCAGCACAGAAACTCTCAAATGCTTAAAAGATAAAACAGGTGGGAAGAAGTTCTCCAAAGAATTTGAAG
AGGCAAGCTCCAAGCTGGAAGAATTTGTGAATGGATTAGATAAGCAGGTGAAAAACGGACCCTCATTAACAGAAGCACTGGAAAATGCTG
GAATTTTCTATGAAGCACAATACAAAGAAGTAAAAGTGGTGGCTAATTGGACATATCAGGCCATGGTCCACGAACTACTAGGCATAAACA
ACAATCGGATTGATCTTTCCAGAGTGCCGGGAATCAGTAAAGACTTAAGAGAAGTGGTCCTATCTGCTGAAAATGATGAATTCTATGCTA
ATAATATGTACCTGAACTTTGCTGAGATTGGTAGCAATATAAAGAATCTCATGGAAGATTTTCAGAAGAAGAAACCAAAAGAACAGCAAA
AACTAGAATCAATAGCAGACATGAAGGCGTTTGTTGAGAATTATCCACAGTTCAAGAAAATGTCTGGGACTGTTTCAAAGCATGTGACAG
TGGTTGGAGAACTGTCTCGATTGGTCAGTGAACGGAATCTGCTGGAGGTTTCAGAGGTTGAGCAAGAACTGGCCTGTCAAAATGACCATT
CTAGTGCTCTCCAGAATATAAAAAGGCTTCTGCAGAACCCCAAAGTGACAGAGTTTGATGCTGCCCGCCTGGTGATGCTTTATGCTTTAC
ATTATGAGCGACACAGCAGCAATAGCCTGCCAGGACTAATGATGGACCTCAGGAATAAAGGTGTTTCTGAGAAGTATCGAAAGCTCGTGT
CTGCAGTTGTTGAATATGGTGGTAAACGAGTCAGAGGAAGTGACCTCTTCAGCCCCAAAGATGCTGTGGCTATCACCAAACAATTCCTCA
AAGGACTGAAGGGAGTAGAAAATGTATATACACAGCATCAACCTTTCCTACATGAAACCCTGGATCATCTCATCAAAGGAAGGCTTAAGG
AAAACCTATATCCTTATTTAGGCCCCAGCACACTCAGAGACAGACCTCAGGATATCATTGTGTTTGTAATTGGAGGAGCCACCTATGAAG
AGGCTCTAACAGTTTATAACCTGAACCGCACCACTCCTGGAGTGAGGATTGTCCTGGGAGGCACCACAGTGCACAACACGAAAAGTTTCC
TAGAGGAAGTTCTGGCTTCTGGACTGCACAGCCGAAGCAAGGAGAGCTCTCAAGTCACATCAAGGTCAGCGAGCAGAAGATGAAACGGTG
GTTGGGGGAAGGGCACAGCTTCCTCTCTTGTCCCCACTACAGGTTTTCCCTACTAAACAAAGGTGTTGGAGAGCAGCTTTGGGTTCTGTG
CTGGTTGTTAGAACTCATCTCCAGGTAGCCCACGGATACGTGGTTGGCACAGACACAAGACTCCCAGAGTTGTCCTAACAATAAGTCTGA
GCCCATCTCAACCCACTTTTCTCCGGTAGTCTTTATGTATCTGTTAGCACAATCACTTCAGTTACTGATGAATTTTGTTGGGATCTGACT
TGGGGAAAGGGTTATCAGAGCCTAGAGGGGCTTAAAAAGTAATCATTTGATGTACATACCACACTCCTTGGCTTCCTTTCTCTTCCCTTA
ACCCTTTCTGCTTTTCATTAACCACATTCCTGCACAACTCATTTCTGAAAACCTACCATGTTTCTTTACAGAGCCATCCAAAAATTTTTT

>In-frame_ENST00000401000_ENST00000369130_TCGA-A7-A13D-01A_RPRD2_chr1_150418877_+_VPS45_chr1_150053424_length(amino acids)=605AA_start in transcript=65_stop in transcript=1882
MAAGGGGGSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSAYPHRLNLFYLANDVIQNCKR
KNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIWEDRNVYPEEMIVALREALTSTNPKAALKSKIVAEFRSQALIEELLLYKRSEDQ
IELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEASSKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANWTYQAM
VHELLGINNNRIDLSRVPGISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKKPKEQQKLESIADMKAFVENYPQFKKMS
GTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDHSSALQNIKRLLQNPKVTEFDAARLVMLYALHYERHSSNSLPGLMMDLRNKGV
SEKYRKLVSAVVEYGGKRVRGSDLFSPKDAVAITKQFLKGLKGVENVYTQHQPFLHETLDHLIKGRLKENLYPYLGPSTLRDRPQDIIVF

--------------------------------------------------------------
>In-frame_ENST00000401000_ENST00000369128_TCGA-A7-A13D-01A_RPRD2_chr1_150418877_+_VPS45_chr1_150053424_length(transcript)=2469nt_BP=857nt
CCGCTCCCGCCGCCGCCGCCGCCGCCGCCGCCAGAGGAGCAGCAGCGCTTGTGCAAACCGGGAAGATGGCGGCCGGCGGCGGCGGAGGCA
GCAGTAAGGCCTCCTCCTCGTCGGCCTCTTCGGCAGGGGCTCTGGAGTCCTCGTTGGATCGAAAATTCCAGTCGGTAACCAACACCATGG
AGTCCATTCAAGGCTTGTCGTCTTGGTGTATAGAGAACAAAAAACACCACAGTACTATCGTCTATCATTGGATGAAGTGGCTCCGGAGAT
CTGCATATCCCCACCGTTTGAATCTCTTTTACCTTGCCAATGATGTCATACAGAACTGTAAAAGGAAAAATGCAATCATATTCCGTGAAT
CATTTGCTGATGTACTTCCTGAAGCAGCTGCTCTAGTGAAGGATCCATCTGTCTCTAAGTCTGTAGAACGAATCTTTAAAATCTGGGAAG
ATAGAAATGTATACCCAGAAGAAATGATTGTGGCATTGAGAGAAGCTTTGACATCTACAAATCCAAAAGCTGCTCTCAAGTCTAAGATAG
TTGCTGAATTTCGATCTCAGGCCCTAATTGAAGAGCTGTTGCTATACAAGCGCTCAGAAGATCAGATAGAACTGAAGGAAAAGCAGTTGT
CAACTATGAGGGTGGATGTGTGCAGCACAGAAACTCTCAAATGCTTAAAAGATAAAACAGGTGGGAAGAAGTTCTCCAAAGAATTTGAAG
AGGCAAGCTCCAAGCTGGAAGAATTTGTGAATGGATTAGATAAGCAGGTGAAAAACGGACCCTCATTAACAGAAGCACTGGAAAATGCTG
GAATTTTCTATGAAGCACAATACAAAGAAGTAAAAGTGGTGGCTAATTGGACATATCAGGCCATGGTCCACGAACTACTAGGCATAAACA
ACAATCGGATTGATCTTTCCAGAGTGCCGGGAATCAGTAAAGACTTAAGAGAAGTGGTCCTATCTGCTGAAAATGATGAATTCTATGCTA
ATAATATGTACCTGAACTTTGCTGAGATTGGTAGCAATATAAAGAATCTCATGGAAGATTTTCAGAAGAAGAAACCAAAAGAACAGCAAA
AACTAGAATCAATAGCAGACATGAAGGCGTTTGTTGAGAATTATCCACAGTTCAAGAAAATGTCTGGGACTGTTTCAAAGCATGTGACAG
TGGTTGGAGAACTGTCTCGATTGGTCAGTGAACGGAATCTGCTGGAGGTTTCAGAGGTTGAGCAAGAACTGGCCTGTCAAAATGACCATT
CTAGTGCTCTCCAGAATATAAAAAGGCTTCTGCAGAACCCCAAAGTGACAGAGTTTGATGCTGCCCGCCTGGTGATGCTTTATGCTTTAC
ATTATGAGCGACACAGCAGCAATAGCCTGCCAGGACTAATGATGGACCTCAGGAATAAAGGTGTTTCTGAGAAGTATCGAAAGCTCGTGT
CTGCAGTTGTTGAATATGGTGGTAAACGAGTCAGAGGAAGTGACCTCTTCAGCCCCAAAGATGCTGTGGCTATCACCAAACAATTCCTCA
AAGGACTGAAGGGAGTAGAAAATGTATATACACAGCATCAACCTTTCCTACATGAAACCCTGGATCATCTCATCAAAGGAAGGCTTAAGG
AAAACCTATATCCTTATTTAGGCCCCAGCACACTCAGAGACAGACCTCAGGATATCATTGTGTTTGTAATTGGAGGAGCCACCTATGAAG
AGGCTCTAACAGTTTATAACCTGAACCGCACCACTCCTGGAGTGAGGATTGTCCTGGGAGGCACCACAGTGCACAACACGAAAAGAGATG
GGGTTTCACTATGTTCCCCTGCCTGGTTTCGAACTCCTGGGCTCAAGCGATCCACCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGCT
TTCCTAGAGGAAGTTCTGGCTTCTGGACTGCACAGCCGAAGCAAGGAGAGCTCTCAAGTCACATCAAGGTCAGCGAGCAGAAGATGAAAC
GGTGGTTGGGGGAAGGGCACAGCTTCCTCTCTTGTCCCCACTACAGGTTTTCCCTACTAAACAAAGGTGTTGGAGAGCAGCTTTGGGTTC
TGTGCTGGTTGTTAGAACTCATCTCCAGGTAGCCCACGGATACGTGGTTGGCACAGACACAAGACTCCCAGAGTTGTCCTAACAATAAGT
CTGAGCCCATCTCAACCCACTTTTCTCCGGTAGTCTTTATGTATCTGTTAGCACAATCACTTCAGTTACTGATGAATTTTGTTGGGATCT
GACTTGGGGAAAGGGTTATCAGAGCCTAGAGGGGCTTAAAAAGTAATCATTTGATGTACATACCACACTCCTTGGCTTCCTTTCTCTTCC
CTTAACCCTTTCTGCTTTTCATTAACCACATTCCTGCACAACTCATTTCTGAAAACCTACCATGTTTCTTTACAGAGCCATCCAAAAATT

>In-frame_ENST00000401000_ENST00000369128_TCGA-A7-A13D-01A_RPRD2_chr1_150418877_+_VPS45_chr1_150053424_length(amino acids)=678AA_start in transcript=65_stop in transcript=2101
MAAGGGGGSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSAYPHRLNLFYLANDVIQNCKR
KNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIWEDRNVYPEEMIVALREALTSTNPKAALKSKIVAEFRSQALIEELLLYKRSEDQ
IELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEASSKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANWTYQAM
VHELLGINNNRIDLSRVPGISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKKPKEQQKLESIADMKAFVENYPQFKKMS
GTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDHSSALQNIKRLLQNPKVTEFDAARLVMLYALHYERHSSNSLPGLMMDLRNKGV
SEKYRKLVSAVVEYGGKRVRGSDLFSPKDAVAITKQFLKGLKGVENVYTQHQPFLHETLDHLIKGRLKENLYPYLGPSTLRDRPQDIIVF
VIGGATYEEALTVYNLNRTTPGVRIVLGGTTVHNTKRDGVSLCSPAWFRTPGLKRSTRLSLPKCWDYSFPRGSSGFWTAQPKQGELSSHI

--------------------------------------------------------------
>In-frame_ENST00000401000_ENST00000535106_TCGA-A7-A13D-01A_RPRD2_chr1_150418877_+_VPS45_chr1_150053424_length(transcript)=2040nt_BP=857nt
CCGCTCCCGCCGCCGCCGCCGCCGCCGCCGCCAGAGGAGCAGCAGCGCTTGTGCAAACCGGGAAGATGGCGGCCGGCGGCGGCGGAGGCA
GCAGTAAGGCCTCCTCCTCGTCGGCCTCTTCGGCAGGGGCTCTGGAGTCCTCGTTGGATCGAAAATTCCAGTCGGTAACCAACACCATGG
AGTCCATTCAAGGCTTGTCGTCTTGGTGTATAGAGAACAAAAAACACCACAGTACTATCGTCTATCATTGGATGAAGTGGCTCCGGAGAT
CTGCATATCCCCACCGTTTGAATCTCTTTTACCTTGCCAATGATGTCATACAGAACTGTAAAAGGAAAAATGCAATCATATTCCGTGAAT
CATTTGCTGATGTACTTCCTGAAGCAGCTGCTCTAGTGAAGGATCCATCTGTCTCTAAGTCTGTAGAACGAATCTTTAAAATCTGGGAAG
ATAGAAATGTATACCCAGAAGAAATGATTGTGGCATTGAGAGAAGCTTTGACATCTACAAATCCAAAAGCTGCTCTCAAGTCTAAGATAG
TTGCTGAATTTCGATCTCAGGCCCTAATTGAAGAGCTGTTGCTATACAAGCGCTCAGAAGATCAGATAGAACTGAAGGAAAAGCAGTTGT
CAACTATGAGGGTGGATGTGTGCAGCACAGAAACTCTCAAATGCTTAAAAGATAAAACAGGTGGGAAGAAGTTCTCCAAAGAATTTGAAG
AGGCAAGCTCCAAGCTGGAAGAATTTGTGAATGGATTAGATAAGCAGGTGAAAAACGGACCCTCATTAACAGAAGCACTGGAAAATGCTG
GAATTTTCTATGAAGCACAATACAAAGAAGTAAAAGTGGTGGCTAATTGGACATATCAGGCCATGGTCCACGAACTACTAGGCATAAACA
ACAATCGGATTGATCTTTCCAGAGTGCCGGGAATCAGTAAAGACTTAAGAGAAGTGGTCCTATCTGCTGAAAATGATGAATTCTATGCTA
ATAATATGTACCTGAACTTTGCTGAGATTGGTAGCAATATAAAGAATCTCATGGAAGATTTTCAGAAGAAGAAACCAAAAGAACAGCAAA
AACTAGAATCAATAGCAGACATGAAGGCGTTTGTTGAGAATTATCCACAGTTCAAGAAAATGTCTGGGACTGTTTCAAAGCATGTGACAG
TGGTTGGAGAACTGTCTCGATTGGTCAGTGAACGGAATCTGCTGGAGGTTTCAGAGGTTGAGCAAGAACTGGCCTGTCAAAATGACCATT
CTAGTGCTCTCCAGAATATAAAAAGGCTTCTGCAGAACCCCAAAGTGACAGAGTTTGATGCTGCCCGCCTGGTGATGCTTTATGCTTTAC
ATTATGAGCGACACAGCAGCAATAGCCTGCCAGGACTAATGATGGACCTCAGGAATAAAGGTGTTTCTGAGAAGTATCGAAAGCTCGTGT
CTGCAGTTGTTGAATATGGTGGTAAACGAGTCAGAGGAAGTGACCTCTTCAGCCCCAAAGATGCTGTGGCTATCACCAAACAATTCCTCA
AAGGACTGAAGGGAGTAGAAAATGTATATACACAGCATCAACCTTTCCTACATGAAACCCTGGATCATCTCATCAAAGGAAGGCTTAAGG
AAAACCTATATCCTTATTTAGGCCCCAGCACACTCAGAGACAGAATTGCCTCTTGTCTCTGATAAAGGCAAGCAACTTTTTCATTTGGTG
AGGAAATGGAGCTATATGATCATGCATTCCAGAATCAGTCAATTCAAAAAGGAAGTACTTTTCATGTTTATACAAATGTAGTAGAATCTT
GTTGCTACAGCTTATTTTTTGTTTCTGTGAAGCAGCAGTCCTTTTTCATTGGCCTTTTTTCCTGCAGTAAATGCTCATAAGAACTGTACC
ATTTACCTCAGGATATCATTGTGTTTGTAATTGGAGGAGCCACCTATGAAGAGGCTCTAACAGTTTATAACCTGAACCGCACCACTCCTG

>In-frame_ENST00000401000_ENST00000535106_TCGA-A7-A13D-01A_RPRD2_chr1_150418877_+_VPS45_chr1_150053424_length(amino acids)=538AA_start in transcript=65_stop in transcript=1681
MAAGGGGGSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSAYPHRLNLFYLANDVIQNCKR
KNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIWEDRNVYPEEMIVALREALTSTNPKAALKSKIVAEFRSQALIEELLLYKRSEDQ
IELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEASSKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANWTYQAM
VHELLGINNNRIDLSRVPGISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKKPKEQQKLESIADMKAFVENYPQFKKMS
GTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDHSSALQNIKRLLQNPKVTEFDAARLVMLYALHYERHSSNSLPGLMMDLRNKGV

--------------------------------------------------------------
>In-frame_ENST00000539519_ENST00000369130_TCGA-A7-A13D-01A_RPRD2_chr1_150418877_+_VPS45_chr1_150053424_length(transcript)=2371nt_BP=814nt
AGCGCTTGTGCAAACCGGGAAGATGGCGGCCGGCGGCGGCGGAGGCAGCAGTAAGGCCTCCTCCTCGTCGGCCTCTTCGGCAGGGGCTCT
GGAGTCCTCGTTGGATCGAAAATTCCAGTCGGTAACCAACACCATGGAGTCCATTCAAGGCTTGTCGTCTTGGTGTATAGAGAACAAAAA
ACACCACAGTACTATCGTCTATCATTGGATGAAGTGGCTCCGGAGATCTGCATATCCCCACCGTTTGAATCTCTTTTACCTTGCCAATGA
TGTCATACAGAACTGTAAAAGGAAAAATGCAATCATATTCCGTGAATCATTTGCTGATGTACTTCCTGAAGCAGCTGCTCTAGTGAAGGA
TCCATCTGTCTCTAAGTCTGTAGAACGAATCTTTAAAATCTGGGAAGATAGAAATGTATACCCAGAAGAAATGATTGTGGCATTGAGAGA
AGCTTTGACATCTACAAATCCAAAAGCTGCTCTCAAGTCTAAGATAGTTGCTGAATTTCGATCTCAGGCCCTAATTGAAGAGCTGTTGCT
ATACAAGCGCTCAGAAGATCAGATAGAACTGAAGGAAAAGCAGTTGTCAACTATGAGGGTGGATGTGTGCAGCACAGAAACTCTCAAATG
CTTAAAAGATAAAACAGGTGGGAAGAAGTTCTCCAAAGAATTTGAAGAGGCAAGCTCCAAGCTGGAAGAATTTGTGAATGGATTAGATAA
GCAGGTGAAAAACGGACCCTCATTAACAGAAGCACTGGAAAATGCTGGAATTTTCTATGAAGCACAATACAAAGAAGTAAAAGTGGTGGC
TAATTGGACATATCAGGCCATGGTCCACGAACTACTAGGCATAAACAACAATCGGATTGATCTTTCCAGAGTGCCGGGAATCAGTAAAGA
CTTAAGAGAAGTGGTCCTATCTGCTGAAAATGATGAATTCTATGCTAATAATATGTACCTGAACTTTGCTGAGATTGGTAGCAATATAAA
GAATCTCATGGAAGATTTTCAGAAGAAGAAACCAAAAGAACAGCAAAAACTAGAATCAATAGCAGACATGAAGGCGTTTGTTGAGAATTA
TCCACAGTTCAAGAAAATGTCTGGGACTGTTTCAAAGCATGTGACAGTGGTTGGAGAACTGTCTCGATTGGTCAGTGAACGGAATCTGCT
GGAGGTTTCAGAGGTTGAGCAAGAACTGGCCTGTCAAAATGACCATTCTAGTGCTCTCCAGAATATAAAAAGGCTTCTGCAGAACCCCAA
AGTGACAGAGTTTGATGCTGCCCGCCTGGTGATGCTTTATGCTTTACATTATGAGCGACACAGCAGCAATAGCCTGCCAGGACTAATGAT
GGACCTCAGGAATAAAGGTGTTTCTGAGAAGTATCGAAAGCTCGTGTCTGCAGTTGTTGAATATGGTGGTAAACGAGTCAGAGGAAGTGA
CCTCTTCAGCCCCAAAGATGCTGTGGCTATCACCAAACAATTCCTCAAAGGACTGAAGGGAGTAGAAAATGTATATACACAGCATCAACC
TTTCCTACATGAAACCCTGGATCATCTCATCAAAGGAAGGCTTAAGGAAAACCTATATCCTTATTTAGGCCCCAGCACACTCAGAGACAG
ACCTCAGGATATCATTGTGTTTGTAATTGGAGGAGCCACCTATGAAGAGGCTCTAACAGTTTATAACCTGAACCGCACCACTCCTGGAGT
GAGGATTGTCCTGGGAGGCACCACAGTGCACAACACGAAAAGTTTCCTAGAGGAAGTTCTGGCTTCTGGACTGCACAGCCGAAGCAAGGA
GAGCTCTCAAGTCACATCAAGGTCAGCGAGCAGAAGATGAAACGGTGGTTGGGGGAAGGGCACAGCTTCCTCTCTTGTCCCCACTACAGG
TTTTCCCTACTAAACAAAGGTGTTGGAGAGCAGCTTTGGGTTCTGTGCTGGTTGTTAGAACTCATCTCCAGGTAGCCCACGGATACGTGG
TTGGCACAGACACAAGACTCCCAGAGTTGTCCTAACAATAAGTCTGAGCCCATCTCAACCCACTTTTCTCCGGTAGTCTTTATGTATCTG
TTAGCACAATCACTTCAGTTACTGATGAATTTTGTTGGGATCTGACTTGGGGAAAGGGTTATCAGAGCCTAGAGGGGCTTAAAAAGTAAT
CATTTGATGTACATACCACACTCCTTGGCTTCCTTTCTCTTCCCTTAACCCTTTCTGCTTTTCATTAACCACATTCCTGCACAACTCATT
TCTGAAAACCTACCATGTTTCTTTACAGAGCCATCCAAAAATTTTTTGTCCCTACATAGCAATTTTCTGTGGCACTGAGAAACCATGTAT

>In-frame_ENST00000539519_ENST00000369130_TCGA-A7-A13D-01A_RPRD2_chr1_150418877_+_VPS45_chr1_150053424_length(amino acids)=605AA_start in transcript=22_stop in transcript=1839
MAAGGGGGSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSAYPHRLNLFYLANDVIQNCKR
KNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIWEDRNVYPEEMIVALREALTSTNPKAALKSKIVAEFRSQALIEELLLYKRSEDQ
IELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEASSKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANWTYQAM
VHELLGINNNRIDLSRVPGISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKKPKEQQKLESIADMKAFVENYPQFKKMS
GTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDHSSALQNIKRLLQNPKVTEFDAARLVMLYALHYERHSSNSLPGLMMDLRNKGV
SEKYRKLVSAVVEYGGKRVRGSDLFSPKDAVAITKQFLKGLKGVENVYTQHQPFLHETLDHLIKGRLKENLYPYLGPSTLRDRPQDIIVF

--------------------------------------------------------------
>In-frame_ENST00000539519_ENST00000369128_TCGA-A7-A13D-01A_RPRD2_chr1_150418877_+_VPS45_chr1_150053424_length(transcript)=2426nt_BP=814nt
AGCGCTTGTGCAAACCGGGAAGATGGCGGCCGGCGGCGGCGGAGGCAGCAGTAAGGCCTCCTCCTCGTCGGCCTCTTCGGCAGGGGCTCT
GGAGTCCTCGTTGGATCGAAAATTCCAGTCGGTAACCAACACCATGGAGTCCATTCAAGGCTTGTCGTCTTGGTGTATAGAGAACAAAAA
ACACCACAGTACTATCGTCTATCATTGGATGAAGTGGCTCCGGAGATCTGCATATCCCCACCGTTTGAATCTCTTTTACCTTGCCAATGA
TGTCATACAGAACTGTAAAAGGAAAAATGCAATCATATTCCGTGAATCATTTGCTGATGTACTTCCTGAAGCAGCTGCTCTAGTGAAGGA
TCCATCTGTCTCTAAGTCTGTAGAACGAATCTTTAAAATCTGGGAAGATAGAAATGTATACCCAGAAGAAATGATTGTGGCATTGAGAGA
AGCTTTGACATCTACAAATCCAAAAGCTGCTCTCAAGTCTAAGATAGTTGCTGAATTTCGATCTCAGGCCCTAATTGAAGAGCTGTTGCT
ATACAAGCGCTCAGAAGATCAGATAGAACTGAAGGAAAAGCAGTTGTCAACTATGAGGGTGGATGTGTGCAGCACAGAAACTCTCAAATG
CTTAAAAGATAAAACAGGTGGGAAGAAGTTCTCCAAAGAATTTGAAGAGGCAAGCTCCAAGCTGGAAGAATTTGTGAATGGATTAGATAA
GCAGGTGAAAAACGGACCCTCATTAACAGAAGCACTGGAAAATGCTGGAATTTTCTATGAAGCACAATACAAAGAAGTAAAAGTGGTGGC
TAATTGGACATATCAGGCCATGGTCCACGAACTACTAGGCATAAACAACAATCGGATTGATCTTTCCAGAGTGCCGGGAATCAGTAAAGA
CTTAAGAGAAGTGGTCCTATCTGCTGAAAATGATGAATTCTATGCTAATAATATGTACCTGAACTTTGCTGAGATTGGTAGCAATATAAA
GAATCTCATGGAAGATTTTCAGAAGAAGAAACCAAAAGAACAGCAAAAACTAGAATCAATAGCAGACATGAAGGCGTTTGTTGAGAATTA
TCCACAGTTCAAGAAAATGTCTGGGACTGTTTCAAAGCATGTGACAGTGGTTGGAGAACTGTCTCGATTGGTCAGTGAACGGAATCTGCT
GGAGGTTTCAGAGGTTGAGCAAGAACTGGCCTGTCAAAATGACCATTCTAGTGCTCTCCAGAATATAAAAAGGCTTCTGCAGAACCCCAA
AGTGACAGAGTTTGATGCTGCCCGCCTGGTGATGCTTTATGCTTTACATTATGAGCGACACAGCAGCAATAGCCTGCCAGGACTAATGAT
GGACCTCAGGAATAAAGGTGTTTCTGAGAAGTATCGAAAGCTCGTGTCTGCAGTTGTTGAATATGGTGGTAAACGAGTCAGAGGAAGTGA
CCTCTTCAGCCCCAAAGATGCTGTGGCTATCACCAAACAATTCCTCAAAGGACTGAAGGGAGTAGAAAATGTATATACACAGCATCAACC
TTTCCTACATGAAACCCTGGATCATCTCATCAAAGGAAGGCTTAAGGAAAACCTATATCCTTATTTAGGCCCCAGCACACTCAGAGACAG
ACCTCAGGATATCATTGTGTTTGTAATTGGAGGAGCCACCTATGAAGAGGCTCTAACAGTTTATAACCTGAACCGCACCACTCCTGGAGT
GAGGATTGTCCTGGGAGGCACCACAGTGCACAACACGAAAAGAGATGGGGTTTCACTATGTTCCCCTGCCTGGTTTCGAACTCCTGGGCT
CAAGCGATCCACCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGCTTTCCTAGAGGAAGTTCTGGCTTCTGGACTGCACAGCCGAAGCA
AGGAGAGCTCTCAAGTCACATCAAGGTCAGCGAGCAGAAGATGAAACGGTGGTTGGGGGAAGGGCACAGCTTCCTCTCTTGTCCCCACTA
CAGGTTTTCCCTACTAAACAAAGGTGTTGGAGAGCAGCTTTGGGTTCTGTGCTGGTTGTTAGAACTCATCTCCAGGTAGCCCACGGATAC
GTGGTTGGCACAGACACAAGACTCCCAGAGTTGTCCTAACAATAAGTCTGAGCCCATCTCAACCCACTTTTCTCCGGTAGTCTTTATGTA
TCTGTTAGCACAATCACTTCAGTTACTGATGAATTTTGTTGGGATCTGACTTGGGGAAAGGGTTATCAGAGCCTAGAGGGGCTTAAAAAG
TAATCATTTGATGTACATACCACACTCCTTGGCTTCCTTTCTCTTCCCTTAACCCTTTCTGCTTTTCATTAACCACATTCCTGCACAACT

>In-frame_ENST00000539519_ENST00000369128_TCGA-A7-A13D-01A_RPRD2_chr1_150418877_+_VPS45_chr1_150053424_length(amino acids)=678AA_start in transcript=22_stop in transcript=2058
MAAGGGGGSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSAYPHRLNLFYLANDVIQNCKR
KNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIWEDRNVYPEEMIVALREALTSTNPKAALKSKIVAEFRSQALIEELLLYKRSEDQ
IELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEASSKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANWTYQAM
VHELLGINNNRIDLSRVPGISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKKPKEQQKLESIADMKAFVENYPQFKKMS
GTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDHSSALQNIKRLLQNPKVTEFDAARLVMLYALHYERHSSNSLPGLMMDLRNKGV
SEKYRKLVSAVVEYGGKRVRGSDLFSPKDAVAITKQFLKGLKGVENVYTQHQPFLHETLDHLIKGRLKENLYPYLGPSTLRDRPQDIIVF
VIGGATYEEALTVYNLNRTTPGVRIVLGGTTVHNTKRDGVSLCSPAWFRTPGLKRSTRLSLPKCWDYSFPRGSSGFWTAQPKQGELSSHI

--------------------------------------------------------------
>In-frame_ENST00000539519_ENST00000535106_TCGA-A7-A13D-01A_RPRD2_chr1_150418877_+_VPS45_chr1_150053424_length(transcript)=1997nt_BP=814nt
AGCGCTTGTGCAAACCGGGAAGATGGCGGCCGGCGGCGGCGGAGGCAGCAGTAAGGCCTCCTCCTCGTCGGCCTCTTCGGCAGGGGCTCT
GGAGTCCTCGTTGGATCGAAAATTCCAGTCGGTAACCAACACCATGGAGTCCATTCAAGGCTTGTCGTCTTGGTGTATAGAGAACAAAAA
ACACCACAGTACTATCGTCTATCATTGGATGAAGTGGCTCCGGAGATCTGCATATCCCCACCGTTTGAATCTCTTTTACCTTGCCAATGA
TGTCATACAGAACTGTAAAAGGAAAAATGCAATCATATTCCGTGAATCATTTGCTGATGTACTTCCTGAAGCAGCTGCTCTAGTGAAGGA
TCCATCTGTCTCTAAGTCTGTAGAACGAATCTTTAAAATCTGGGAAGATAGAAATGTATACCCAGAAGAAATGATTGTGGCATTGAGAGA
AGCTTTGACATCTACAAATCCAAAAGCTGCTCTCAAGTCTAAGATAGTTGCTGAATTTCGATCTCAGGCCCTAATTGAAGAGCTGTTGCT
ATACAAGCGCTCAGAAGATCAGATAGAACTGAAGGAAAAGCAGTTGTCAACTATGAGGGTGGATGTGTGCAGCACAGAAACTCTCAAATG
CTTAAAAGATAAAACAGGTGGGAAGAAGTTCTCCAAAGAATTTGAAGAGGCAAGCTCCAAGCTGGAAGAATTTGTGAATGGATTAGATAA
GCAGGTGAAAAACGGACCCTCATTAACAGAAGCACTGGAAAATGCTGGAATTTTCTATGAAGCACAATACAAAGAAGTAAAAGTGGTGGC
TAATTGGACATATCAGGCCATGGTCCACGAACTACTAGGCATAAACAACAATCGGATTGATCTTTCCAGAGTGCCGGGAATCAGTAAAGA
CTTAAGAGAAGTGGTCCTATCTGCTGAAAATGATGAATTCTATGCTAATAATATGTACCTGAACTTTGCTGAGATTGGTAGCAATATAAA
GAATCTCATGGAAGATTTTCAGAAGAAGAAACCAAAAGAACAGCAAAAACTAGAATCAATAGCAGACATGAAGGCGTTTGTTGAGAATTA
TCCACAGTTCAAGAAAATGTCTGGGACTGTTTCAAAGCATGTGACAGTGGTTGGAGAACTGTCTCGATTGGTCAGTGAACGGAATCTGCT
GGAGGTTTCAGAGGTTGAGCAAGAACTGGCCTGTCAAAATGACCATTCTAGTGCTCTCCAGAATATAAAAAGGCTTCTGCAGAACCCCAA
AGTGACAGAGTTTGATGCTGCCCGCCTGGTGATGCTTTATGCTTTACATTATGAGCGACACAGCAGCAATAGCCTGCCAGGACTAATGAT
GGACCTCAGGAATAAAGGTGTTTCTGAGAAGTATCGAAAGCTCGTGTCTGCAGTTGTTGAATATGGTGGTAAACGAGTCAGAGGAAGTGA
CCTCTTCAGCCCCAAAGATGCTGTGGCTATCACCAAACAATTCCTCAAAGGACTGAAGGGAGTAGAAAATGTATATACACAGCATCAACC
TTTCCTACATGAAACCCTGGATCATCTCATCAAAGGAAGGCTTAAGGAAAACCTATATCCTTATTTAGGCCCCAGCACACTCAGAGACAG
AATTGCCTCTTGTCTCTGATAAAGGCAAGCAACTTTTTCATTTGGTGAGGAAATGGAGCTATATGATCATGCATTCCAGAATCAGTCAAT
TCAAAAAGGAAGTACTTTTCATGTTTATACAAATGTAGTAGAATCTTGTTGCTACAGCTTATTTTTTGTTTCTGTGAAGCAGCAGTCCTT
TTTCATTGGCCTTTTTTCCTGCAGTAAATGCTCATAAGAACTGTACCATTTACCTCAGGATATCATTGTGTTTGTAATTGGAGGAGCCAC
CTATGAAGAGGCTCTAACAGTTTATAACCTGAACCGCACCACTCCTGGAGTGAGGATTGTCCTGGGAGGCACCACAGTGCACAACACGAA

>In-frame_ENST00000539519_ENST00000535106_TCGA-A7-A13D-01A_RPRD2_chr1_150418877_+_VPS45_chr1_150053424_length(amino acids)=538AA_start in transcript=22_stop in transcript=1638
MAAGGGGGSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSAYPHRLNLFYLANDVIQNCKR
KNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIWEDRNVYPEEMIVALREALTSTNPKAALKSKIVAEFRSQALIEELLLYKRSEDQ
IELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEASSKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANWTYQAM
VHELLGINNNRIDLSRVPGISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKKPKEQQKLESIADMKAFVENYPQFKKMS
GTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDHSSALQNIKRLLQNPKVTEFDAARLVMLYALHYERHSSNSLPGLMMDLRNKGV

--------------------------------------------------------------
>In-frame_ENST00000369068_ENST00000369130_TCGA-A7-A13D-01A_RPRD2_chr1_150418877_+_VPS45_chr1_150053424_length(transcript)=2431nt_BP=874nt
GAAGATGGCGGCCGGCGGCGGCGGAGGCAGCAGTAAGGCCTCCTCCTCGTCGGCCTCTTCGGCAGGGGCTCTGGAGTCCTCGTTGGATCG
AAAATTCCAGTCGGTAACCAACACCATGGAGTCCATTCAAGGCTTGTCGTCTTGGTGTATAGAGAACAAAAAACACCACAGTACTATCGT
CTATCATTGGATGAAGTGGCTCCGGAGATCTGCATATCCCCACCGTTTGAATCTCTTTTACCTTGCCAATGATGTCATACAGAACTGTAA
AAGGAAAAATGCAATCATATTCCGTGAATCATTTGCTGATGTACTTCCTGAAGCAGCTGCTCTAGTGAAGGATCCATCTGTCTCTAAGTC
TGTAGAACGAATCTTTAAAATCTGGGAAGATAGAAATGTATACCCAGAAGAAATGATTGTGGCATTGAGAGAAGCTTTGAGTACCACTTT
CAAAACTCAGAAGCAGCTGAAAGAAAATCTGAACAAACAACCGAATAAGCAGTGGAAGAAATCACAAACATCTACAAATCCAAAAGCTGC
TCTCAAGTCTAAGATAGTTGCTGAATTTCGATCTCAGGCCCTAATTGAAGAGCTGTTGCTATACAAGCGCTCAGAAGATCAGATAGAACT
GAAGGAAAAGCAGTTGTCAACTATGAGGGTGGATGTGTGCAGCACAGAAACTCTCAAATGCTTAAAAGATAAAACAGGTGGGAAGAAGTT
CTCCAAAGAATTTGAAGAGGCAAGCTCCAAGCTGGAAGAATTTGTGAATGGATTAGATAAGCAGGTGAAAAACGGACCCTCATTAACAGA
AGCACTGGAAAATGCTGGAATTTTCTATGAAGCACAATACAAAGAAGTAAAAGTGGTGGCTAATTGGACATATCAGGCCATGGTCCACGA
ACTACTAGGCATAAACAACAATCGGATTGATCTTTCCAGAGTGCCGGGAATCAGTAAAGACTTAAGAGAAGTGGTCCTATCTGCTGAAAA
TGATGAATTCTATGCTAATAATATGTACCTGAACTTTGCTGAGATTGGTAGCAATATAAAGAATCTCATGGAAGATTTTCAGAAGAAGAA
ACCAAAAGAACAGCAAAAACTAGAATCAATAGCAGACATGAAGGCGTTTGTTGAGAATTATCCACAGTTCAAGAAAATGTCTGGGACTGT
TTCAAAGCATGTGACAGTGGTTGGAGAACTGTCTCGATTGGTCAGTGAACGGAATCTGCTGGAGGTTTCAGAGGTTGAGCAAGAACTGGC
CTGTCAAAATGACCATTCTAGTGCTCTCCAGAATATAAAAAGGCTTCTGCAGAACCCCAAAGTGACAGAGTTTGATGCTGCCCGCCTGGT
GATGCTTTATGCTTTACATTATGAGCGACACAGCAGCAATAGCCTGCCAGGACTAATGATGGACCTCAGGAATAAAGGTGTTTCTGAGAA
GTATCGAAAGCTCGTGTCTGCAGTTGTTGAATATGGTGGTAAACGAGTCAGAGGAAGTGACCTCTTCAGCCCCAAAGATGCTGTGGCTAT
CACCAAACAATTCCTCAAAGGACTGAAGGGAGTAGAAAATGTATATACACAGCATCAACCTTTCCTACATGAAACCCTGGATCATCTCAT
CAAAGGAAGGCTTAAGGAAAACCTATATCCTTATTTAGGCCCCAGCACACTCAGAGACAGACCTCAGGATATCATTGTGTTTGTAATTGG
AGGAGCCACCTATGAAGAGGCTCTAACAGTTTATAACCTGAACCGCACCACTCCTGGAGTGAGGATTGTCCTGGGAGGCACCACAGTGCA
CAACACGAAAAGTTTCCTAGAGGAAGTTCTGGCTTCTGGACTGCACAGCCGAAGCAAGGAGAGCTCTCAAGTCACATCAAGGTCAGCGAG
CAGAAGATGAAACGGTGGTTGGGGGAAGGGCACAGCTTCCTCTCTTGTCCCCACTACAGGTTTTCCCTACTAAACAAAGGTGTTGGAGAG
CAGCTTTGGGTTCTGTGCTGGTTGTTAGAACTCATCTCCAGGTAGCCCACGGATACGTGGTTGGCACAGACACAAGACTCCCAGAGTTGT
CCTAACAATAAGTCTGAGCCCATCTCAACCCACTTTTCTCCGGTAGTCTTTATGTATCTGTTAGCACAATCACTTCAGTTACTGATGAAT
TTTGTTGGGATCTGACTTGGGGAAAGGGTTATCAGAGCCTAGAGGGGCTTAAAAAGTAATCATTTGATGTACATACCACACTCCTTGGCT
TCCTTTCTCTTCCCTTAACCCTTTCTGCTTTTCATTAACCACATTCCTGCACAACTCATTTCTGAAAACCTACCATGTTTCTTTACAGAG
CCATCCAAAAATTTTTTGTCCCTACATAGCAATTTTCTGTGGCACTGAGAAACCATGTATGACCACAATAAAAATCCATTTTGTGAAAGG

>In-frame_ENST00000369068_ENST00000369130_TCGA-A7-A13D-01A_RPRD2_chr1_150418877_+_VPS45_chr1_150053424_length(amino acids)=631AA_start in transcript=4_stop in transcript=1899
MAAGGGGGSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSAYPHRLNLFYLANDVIQNCKR
KNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIWEDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAAL
KSKIVAEFRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEASSKLEEFVNGLDKQVKNGPSLTEA
LENAGIFYEAQYKEVKVVANWTYQAMVHELLGINNNRIDLSRVPGISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKKP
KEQQKLESIADMKAFVENYPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDHSSALQNIKRLLQNPKVTEFDAARLVM
LYALHYERHSSNSLPGLMMDLRNKGVSEKYRKLVSAVVEYGGKRVRGSDLFSPKDAVAITKQFLKGLKGVENVYTQHQPFLHETLDHLIK
GRLKENLYPYLGPSTLRDRPQDIIVFVIGGATYEEALTVYNLNRTTPGVRIVLGGTTVHNTKSFLEEVLASGLHSRSKESSQVTSRSASR

--------------------------------------------------------------
>In-frame_ENST00000369068_ENST00000369128_TCGA-A7-A13D-01A_RPRD2_chr1_150418877_+_VPS45_chr1_150053424_length(transcript)=2486nt_BP=874nt
GAAGATGGCGGCCGGCGGCGGCGGAGGCAGCAGTAAGGCCTCCTCCTCGTCGGCCTCTTCGGCAGGGGCTCTGGAGTCCTCGTTGGATCG
AAAATTCCAGTCGGTAACCAACACCATGGAGTCCATTCAAGGCTTGTCGTCTTGGTGTATAGAGAACAAAAAACACCACAGTACTATCGT
CTATCATTGGATGAAGTGGCTCCGGAGATCTGCATATCCCCACCGTTTGAATCTCTTTTACCTTGCCAATGATGTCATACAGAACTGTAA
AAGGAAAAATGCAATCATATTCCGTGAATCATTTGCTGATGTACTTCCTGAAGCAGCTGCTCTAGTGAAGGATCCATCTGTCTCTAAGTC
TGTAGAACGAATCTTTAAAATCTGGGAAGATAGAAATGTATACCCAGAAGAAATGATTGTGGCATTGAGAGAAGCTTTGAGTACCACTTT
CAAAACTCAGAAGCAGCTGAAAGAAAATCTGAACAAACAACCGAATAAGCAGTGGAAGAAATCACAAACATCTACAAATCCAAAAGCTGC
TCTCAAGTCTAAGATAGTTGCTGAATTTCGATCTCAGGCCCTAATTGAAGAGCTGTTGCTATACAAGCGCTCAGAAGATCAGATAGAACT
GAAGGAAAAGCAGTTGTCAACTATGAGGGTGGATGTGTGCAGCACAGAAACTCTCAAATGCTTAAAAGATAAAACAGGTGGGAAGAAGTT
CTCCAAAGAATTTGAAGAGGCAAGCTCCAAGCTGGAAGAATTTGTGAATGGATTAGATAAGCAGGTGAAAAACGGACCCTCATTAACAGA
AGCACTGGAAAATGCTGGAATTTTCTATGAAGCACAATACAAAGAAGTAAAAGTGGTGGCTAATTGGACATATCAGGCCATGGTCCACGA
ACTACTAGGCATAAACAACAATCGGATTGATCTTTCCAGAGTGCCGGGAATCAGTAAAGACTTAAGAGAAGTGGTCCTATCTGCTGAAAA
TGATGAATTCTATGCTAATAATATGTACCTGAACTTTGCTGAGATTGGTAGCAATATAAAGAATCTCATGGAAGATTTTCAGAAGAAGAA
ACCAAAAGAACAGCAAAAACTAGAATCAATAGCAGACATGAAGGCGTTTGTTGAGAATTATCCACAGTTCAAGAAAATGTCTGGGACTGT
TTCAAAGCATGTGACAGTGGTTGGAGAACTGTCTCGATTGGTCAGTGAACGGAATCTGCTGGAGGTTTCAGAGGTTGAGCAAGAACTGGC
CTGTCAAAATGACCATTCTAGTGCTCTCCAGAATATAAAAAGGCTTCTGCAGAACCCCAAAGTGACAGAGTTTGATGCTGCCCGCCTGGT
GATGCTTTATGCTTTACATTATGAGCGACACAGCAGCAATAGCCTGCCAGGACTAATGATGGACCTCAGGAATAAAGGTGTTTCTGAGAA
GTATCGAAAGCTCGTGTCTGCAGTTGTTGAATATGGTGGTAAACGAGTCAGAGGAAGTGACCTCTTCAGCCCCAAAGATGCTGTGGCTAT
CACCAAACAATTCCTCAAAGGACTGAAGGGAGTAGAAAATGTATATACACAGCATCAACCTTTCCTACATGAAACCCTGGATCATCTCAT
CAAAGGAAGGCTTAAGGAAAACCTATATCCTTATTTAGGCCCCAGCACACTCAGAGACAGACCTCAGGATATCATTGTGTTTGTAATTGG
AGGAGCCACCTATGAAGAGGCTCTAACAGTTTATAACCTGAACCGCACCACTCCTGGAGTGAGGATTGTCCTGGGAGGCACCACAGTGCA
CAACACGAAAAGAGATGGGGTTTCACTATGTTCCCCTGCCTGGTTTCGAACTCCTGGGCTCAAGCGATCCACCCGCCTCAGCCTCCCAAA
GTGCTGGGATTACAGCTTTCCTAGAGGAAGTTCTGGCTTCTGGACTGCACAGCCGAAGCAAGGAGAGCTCTCAAGTCACATCAAGGTCAG
CGAGCAGAAGATGAAACGGTGGTTGGGGGAAGGGCACAGCTTCCTCTCTTGTCCCCACTACAGGTTTTCCCTACTAAACAAAGGTGTTGG
AGAGCAGCTTTGGGTTCTGTGCTGGTTGTTAGAACTCATCTCCAGGTAGCCCACGGATACGTGGTTGGCACAGACACAAGACTCCCAGAG
TTGTCCTAACAATAAGTCTGAGCCCATCTCAACCCACTTTTCTCCGGTAGTCTTTATGTATCTGTTAGCACAATCACTTCAGTTACTGAT
GAATTTTGTTGGGATCTGACTTGGGGAAAGGGTTATCAGAGCCTAGAGGGGCTTAAAAAGTAATCATTTGATGTACATACCACACTCCTT
GGCTTCCTTTCTCTTCCCTTAACCCTTTCTGCTTTTCATTAACCACATTCCTGCACAACTCATTTCTGAAAACCTACCATGTTTCTTTAC

>In-frame_ENST00000369068_ENST00000369128_TCGA-A7-A13D-01A_RPRD2_chr1_150418877_+_VPS45_chr1_150053424_length(amino acids)=704AA_start in transcript=4_stop in transcript=2118
MAAGGGGGSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSAYPHRLNLFYLANDVIQNCKR
KNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIWEDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAAL
KSKIVAEFRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEASSKLEEFVNGLDKQVKNGPSLTEA
LENAGIFYEAQYKEVKVVANWTYQAMVHELLGINNNRIDLSRVPGISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKKP
KEQQKLESIADMKAFVENYPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDHSSALQNIKRLLQNPKVTEFDAARLVM
LYALHYERHSSNSLPGLMMDLRNKGVSEKYRKLVSAVVEYGGKRVRGSDLFSPKDAVAITKQFLKGLKGVENVYTQHQPFLHETLDHLIK
GRLKENLYPYLGPSTLRDRPQDIIVFVIGGATYEEALTVYNLNRTTPGVRIVLGGTTVHNTKRDGVSLCSPAWFRTPGLKRSTRLSLPKC

--------------------------------------------------------------
>In-frame_ENST00000369068_ENST00000535106_TCGA-A7-A13D-01A_RPRD2_chr1_150418877_+_VPS45_chr1_150053424_length(transcript)=2057nt_BP=874nt
GAAGATGGCGGCCGGCGGCGGCGGAGGCAGCAGTAAGGCCTCCTCCTCGTCGGCCTCTTCGGCAGGGGCTCTGGAGTCCTCGTTGGATCG
AAAATTCCAGTCGGTAACCAACACCATGGAGTCCATTCAAGGCTTGTCGTCTTGGTGTATAGAGAACAAAAAACACCACAGTACTATCGT
CTATCATTGGATGAAGTGGCTCCGGAGATCTGCATATCCCCACCGTTTGAATCTCTTTTACCTTGCCAATGATGTCATACAGAACTGTAA
AAGGAAAAATGCAATCATATTCCGTGAATCATTTGCTGATGTACTTCCTGAAGCAGCTGCTCTAGTGAAGGATCCATCTGTCTCTAAGTC
TGTAGAACGAATCTTTAAAATCTGGGAAGATAGAAATGTATACCCAGAAGAAATGATTGTGGCATTGAGAGAAGCTTTGAGTACCACTTT
CAAAACTCAGAAGCAGCTGAAAGAAAATCTGAACAAACAACCGAATAAGCAGTGGAAGAAATCACAAACATCTACAAATCCAAAAGCTGC
TCTCAAGTCTAAGATAGTTGCTGAATTTCGATCTCAGGCCCTAATTGAAGAGCTGTTGCTATACAAGCGCTCAGAAGATCAGATAGAACT
GAAGGAAAAGCAGTTGTCAACTATGAGGGTGGATGTGTGCAGCACAGAAACTCTCAAATGCTTAAAAGATAAAACAGGTGGGAAGAAGTT
CTCCAAAGAATTTGAAGAGGCAAGCTCCAAGCTGGAAGAATTTGTGAATGGATTAGATAAGCAGGTGAAAAACGGACCCTCATTAACAGA
AGCACTGGAAAATGCTGGAATTTTCTATGAAGCACAATACAAAGAAGTAAAAGTGGTGGCTAATTGGACATATCAGGCCATGGTCCACGA
ACTACTAGGCATAAACAACAATCGGATTGATCTTTCCAGAGTGCCGGGAATCAGTAAAGACTTAAGAGAAGTGGTCCTATCTGCTGAAAA
TGATGAATTCTATGCTAATAATATGTACCTGAACTTTGCTGAGATTGGTAGCAATATAAAGAATCTCATGGAAGATTTTCAGAAGAAGAA
ACCAAAAGAACAGCAAAAACTAGAATCAATAGCAGACATGAAGGCGTTTGTTGAGAATTATCCACAGTTCAAGAAAATGTCTGGGACTGT
TTCAAAGCATGTGACAGTGGTTGGAGAACTGTCTCGATTGGTCAGTGAACGGAATCTGCTGGAGGTTTCAGAGGTTGAGCAAGAACTGGC
CTGTCAAAATGACCATTCTAGTGCTCTCCAGAATATAAAAAGGCTTCTGCAGAACCCCAAAGTGACAGAGTTTGATGCTGCCCGCCTGGT
GATGCTTTATGCTTTACATTATGAGCGACACAGCAGCAATAGCCTGCCAGGACTAATGATGGACCTCAGGAATAAAGGTGTTTCTGAGAA
GTATCGAAAGCTCGTGTCTGCAGTTGTTGAATATGGTGGTAAACGAGTCAGAGGAAGTGACCTCTTCAGCCCCAAAGATGCTGTGGCTAT
CACCAAACAATTCCTCAAAGGACTGAAGGGAGTAGAAAATGTATATACACAGCATCAACCTTTCCTACATGAAACCCTGGATCATCTCAT
CAAAGGAAGGCTTAAGGAAAACCTATATCCTTATTTAGGCCCCAGCACACTCAGAGACAGAATTGCCTCTTGTCTCTGATAAAGGCAAGC
AACTTTTTCATTTGGTGAGGAAATGGAGCTATATGATCATGCATTCCAGAATCAGTCAATTCAAAAAGGAAGTACTTTTCATGTTTATAC
AAATGTAGTAGAATCTTGTTGCTACAGCTTATTTTTTGTTTCTGTGAAGCAGCAGTCCTTTTTCATTGGCCTTTTTTCCTGCAGTAAATG
CTCATAAGAACTGTACCATTTACCTCAGGATATCATTGTGTTTGTAATTGGAGGAGCCACCTATGAAGAGGCTCTAACAGTTTATAACCT

>In-frame_ENST00000369068_ENST00000535106_TCGA-A7-A13D-01A_RPRD2_chr1_150418877_+_VPS45_chr1_150053424_length(amino acids)=564AA_start in transcript=4_stop in transcript=1698
MAAGGGGGSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSAYPHRLNLFYLANDVIQNCKR
KNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIWEDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAAL
KSKIVAEFRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEASSKLEEFVNGLDKQVKNGPSLTEA
LENAGIFYEAQYKEVKVVANWTYQAMVHELLGINNNRIDLSRVPGISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKKP
KEQQKLESIADMKAFVENYPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDHSSALQNIKRLLQNPKVTEFDAARLVM
LYALHYERHSSNSLPGLMMDLRNKGVSEKYRKLVSAVVEYGGKRVRGSDLFSPKDAVAITKQFLKGLKGVENVYTQHQPFLHETLDHLIK

--------------------------------------------------------------

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Fusion Gene PPI Analysis for RPRD2-VPS45


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RPRD2-VPS45


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for RPRD2-VPS45


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneRPRD2C0033578Prostatic Neoplasms1CTD_human
HgeneRPRD2C0376358Malignant neoplasm of prostate1CTD_human
TgeneVPS45C3809031NEUTROPENIA, SEVERE CONGENITAL, 5, AUTOSOMAL RECESSIVE2CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneVPS45C0340970Congenital neutropenia1CTD_human;GENOMICS_ENGLAND
TgeneVPS45C1853118Severe congenital neutropenia1CTD_human
TgeneVPS45C2931351Familial myelofibrosis1CTD_human
TgeneVPS45C4755251Congenital neutropenia, myelofibrosis, nephromegaly syndrome1GENOMICS_ENGLAND