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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SCMH1-HOOK3 (FusionGDB2 ID:79163)

Fusion Gene Summary for SCMH1-HOOK3

check button Fusion gene summary
Fusion gene informationFusion gene name: SCMH1-HOOK3
Fusion gene ID: 79163
HgeneTgene
Gene symbol

SCMH1

HOOK3

Gene ID

22955

84376

Gene nameScm polycomb group protein homolog 1hook microtubule tethering protein 3
SynonymsScml3HK3
Cytomap

1p34.2

8p11.21

Type of geneprotein-codingprotein-coding
Descriptionpolycomb protein SCMH1sex comb on midleg homolog 1protein Hook homolog 3h-hook3hHK3hook homolog 3
Modification date2020031320200313
UniProtAcc.

Q86VS8

Ensembl transtripts involved in fusion geneENST00000456518, ENST00000397174, 
ENST00000402904, ENST00000361191, 
ENST00000397171, ENST00000361705, 
ENST00000326197, ENST00000372595, 
ENST00000337495, ENST00000372596, 
ENST00000372597, ENST00000472037, 
ENST00000307602, ENST00000524839, 
Fusion gene scores* DoF score18 X 14 X 11=277214 X 10 X 7=980
# samples 2416
** MAII scorelog2(24/2772*10)=-3.52982094652869
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(16/980*10)=-2.61470984411521
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SCMH1 [Title/Abstract] AND HOOK3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSCMH1(41578955)-HOOK3(42761316), # samples:2
Anticipated loss of major functional domain due to fusion event.SCMH1-HOOK3 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
SCMH1-HOOK3 seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
SCMH1-HOOK3 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
SCMH1-HOOK3 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across SCMH1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across HOOK3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-HB-A5W3-01ASCMH1chr1

41578955

-HOOK3chr8

42761316

+
ChimerDB4SARCTCGA-HB-A5W3-01ASCMH1chr1

41578955

-HOOK3chr8

42761316

+


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Fusion Gene ORF analysis for SCMH1-HOOK3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
intron-3CDSENST00000456518ENST00000307602SCMH1chr1

41578955

-HOOK3chr8

42761316

+
intron-intronENST00000456518ENST00000524839SCMH1chr1

41578955

-HOOK3chr8

42761316

+
In-frameENST00000397174ENST00000307602SCMH1chr1

41578955

-HOOK3chr8

42761316

+
5CDS-intronENST00000397174ENST00000524839SCMH1chr1

41578955

-HOOK3chr8

42761316

+
In-frameENST00000402904ENST00000307602SCMH1chr1

41578955

-HOOK3chr8

42761316

+
5CDS-intronENST00000402904ENST00000524839SCMH1chr1

41578955

-HOOK3chr8

42761316

+
Frame-shiftENST00000361191ENST00000307602SCMH1chr1

41578955

-HOOK3chr8

42761316

+
5CDS-intronENST00000361191ENST00000524839SCMH1chr1

41578955

-HOOK3chr8

42761316

+
In-frameENST00000397171ENST00000307602SCMH1chr1

41578955

-HOOK3chr8

42761316

+
5CDS-intronENST00000397171ENST00000524839SCMH1chr1

41578955

-HOOK3chr8

42761316

+
Frame-shiftENST00000361705ENST00000307602SCMH1chr1

41578955

-HOOK3chr8

42761316

+
5CDS-intronENST00000361705ENST00000524839SCMH1chr1

41578955

-HOOK3chr8

42761316

+
In-frameENST00000326197ENST00000307602SCMH1chr1

41578955

-HOOK3chr8

42761316

+
5CDS-intronENST00000326197ENST00000524839SCMH1chr1

41578955

-HOOK3chr8

42761316

+
Frame-shiftENST00000372595ENST00000307602SCMH1chr1

41578955

-HOOK3chr8

42761316

+
5CDS-intronENST00000372595ENST00000524839SCMH1chr1

41578955

-HOOK3chr8

42761316

+
Frame-shiftENST00000337495ENST00000307602SCMH1chr1

41578955

-HOOK3chr8

42761316

+
5CDS-intronENST00000337495ENST00000524839SCMH1chr1

41578955

-HOOK3chr8

42761316

+
In-frameENST00000372596ENST00000307602SCMH1chr1

41578955

-HOOK3chr8

42761316

+
5CDS-intronENST00000372596ENST00000524839SCMH1chr1

41578955

-HOOK3chr8

42761316

+
Frame-shiftENST00000372597ENST00000307602SCMH1chr1

41578955

-HOOK3chr8

42761316

+
5CDS-intronENST00000372597ENST00000524839SCMH1chr1

41578955

-HOOK3chr8

42761316

+
intron-3CDSENST00000472037ENST00000307602SCMH1chr1

41578955

-HOOK3chr8

42761316

+
intron-intronENST00000472037ENST00000524839SCMH1chr1

41578955

-HOOK3chr8

42761316

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000397174SCMH1chr141578955-ENST00000307602HOOK3chr842761316+15225108410513183710
ENST00000402904SCMH1chr141578955-ENST00000307602HOOK3chr842761316+15225108410513183710
ENST00000397171SCMH1chr141578955-ENST00000307602HOOK3chr842761316+151319909573089710
ENST00000326197SCMH1chr141578955-ENST00000307602HOOK3chr842761316+1515610159823114710
ENST00000372596SCMH1chr141578955-ENST00000307602HOOK3chr842761316+15270112910963228710

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000397174ENST00000307602SCMH1chr141578955-HOOK3chr842761316+0.0007424890.9992575
ENST00000402904ENST00000307602SCMH1chr141578955-HOOK3chr842761316+0.0007424890.9992575
ENST00000397171ENST00000307602SCMH1chr141578955-HOOK3chr842761316+0.0007330740.9992669
ENST00000326197ENST00000307602SCMH1chr141578955-HOOK3chr842761316+0.0007400870.9992599
ENST00000372596ENST00000307602SCMH1chr141578955-HOOK3chr842761316+0.0007429090.999257

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Fusion Genomic Features for SCMH1-HOOK3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SCMH1chr141578954-HOOK3chr842761315+1.74E-070.9999999
SCMH1chr141578954-HOOK3chr842761315+1.74E-070.9999999

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SCMH1-HOOK3


check button Go to

FGviewer for the breakpoints of chr1:41578955-chr8:42761316

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.HOOK3

Q86VS8

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Probably serves as a target for the spiC protein from Salmonella typhimurium, which inactivates it, leading to a strong alteration in cellular trafficking (By similarity). Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). May regulate clearance of endocytosed receptors such as MSR1. Participates in defining the architecture and localization of the Golgi complex. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (PubMed:25035494). FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell (PubMed:32073997). {ECO:0000250|UniProtKB:Q8BUK6, ECO:0000269|PubMed:11238449, ECO:0000269|PubMed:17237231, ECO:0000269|PubMed:18799622, ECO:0000269|PubMed:25035494, ECO:0000269|PubMed:32073997}.; FUNCTION: (Microbial infection) May serve as a target for the spiC protein from Salmonella typhimurium, which inactivates it, leading to a strong alteration in cellular trafficking. {ECO:0000305}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSCMH1chr1:41578955chr8:42761316ENST00000326197-715134_235238.33333333333334661.0RepeatNote=MBT 2
HgeneSCMH1chr1:41578955chr8:42761316ENST00000326197-71528_126238.33333333333334661.0RepeatNote=MBT 1
HgeneSCMH1chr1:41578955chr8:42761316ENST00000337495-815134_235248.33333333333334649.0RepeatNote=MBT 2
HgeneSCMH1chr1:41578955chr8:42761316ENST00000337495-81528_126248.33333333333334649.0RepeatNote=MBT 1
HgeneSCMH1chr1:41578955chr8:42761316ENST00000361191-51228_126177.33333333333334578.0RepeatNote=MBT 1
HgeneSCMH1chr1:41578955chr8:42761316ENST00000361705-61328_126191.33333333333334592.0RepeatNote=MBT 1
HgeneSCMH1chr1:41578955chr8:42761316ENST00000372595-71528_126177.33333333333334600.0RepeatNote=MBT 1
HgeneSCMH1chr1:41578955chr8:42761316ENST00000372596-91628_126177.33333333333334578.0RepeatNote=MBT 1
HgeneSCMH1chr1:41578955chr8:42761316ENST00000372597-81528_126191.33333333333334592.0RepeatNote=MBT 1
HgeneSCMH1chr1:41578955chr8:42761316ENST00000397171-71428_126177.33333333333334578.0RepeatNote=MBT 1
HgeneSCMH1chr1:41578955chr8:42761316ENST00000402904-816134_235238.33333333333334661.0RepeatNote=MBT 2
HgeneSCMH1chr1:41578955chr8:42761316ENST00000402904-81628_126238.33333333333334661.0RepeatNote=MBT 1
TgeneHOOK3chr1:41578955chr8:42761316ENST00000307602022167_43319.0719.0Coiled coilOntology_term=ECO:0000255
TgeneHOOK3chr1:41578955chr8:42761316ENST00000307602022462_66719.0719.0Coiled coilOntology_term=ECO:0000255
TgeneHOOK3chr1:41578955chr8:42761316ENST00000307602022553_71819.0719.0RegionNote=Required for association with Golgi

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSCMH1chr1:41578955chr8:42761316ENST00000326197-715593_658238.33333333333334661.0DomainSAM
HgeneSCMH1chr1:41578955chr8:42761316ENST00000337495-815593_658248.33333333333334649.0DomainSAM
HgeneSCMH1chr1:41578955chr8:42761316ENST00000361191-512593_658177.33333333333334578.0DomainSAM
HgeneSCMH1chr1:41578955chr8:42761316ENST00000361705-613593_658191.33333333333334592.0DomainSAM
HgeneSCMH1chr1:41578955chr8:42761316ENST00000372595-715593_658177.33333333333334600.0DomainSAM
HgeneSCMH1chr1:41578955chr8:42761316ENST00000372596-916593_658177.33333333333334578.0DomainSAM
HgeneSCMH1chr1:41578955chr8:42761316ENST00000372597-815593_658191.33333333333334592.0DomainSAM
HgeneSCMH1chr1:41578955chr8:42761316ENST00000397171-714593_658177.33333333333334578.0DomainSAM
HgeneSCMH1chr1:41578955chr8:42761316ENST00000402904-816593_658238.33333333333334661.0DomainSAM
HgeneSCMH1chr1:41578955chr8:42761316ENST00000456518-19593_6580481.0DomainSAM
HgeneSCMH1chr1:41578955chr8:42761316ENST00000361191-512134_235177.33333333333334578.0RepeatNote=MBT 2
HgeneSCMH1chr1:41578955chr8:42761316ENST00000361705-613134_235191.33333333333334592.0RepeatNote=MBT 2
HgeneSCMH1chr1:41578955chr8:42761316ENST00000372595-715134_235177.33333333333334600.0RepeatNote=MBT 2
HgeneSCMH1chr1:41578955chr8:42761316ENST00000372596-916134_235177.33333333333334578.0RepeatNote=MBT 2
HgeneSCMH1chr1:41578955chr8:42761316ENST00000372597-815134_235191.33333333333334592.0RepeatNote=MBT 2
HgeneSCMH1chr1:41578955chr8:42761316ENST00000397171-714134_235177.33333333333334578.0RepeatNote=MBT 2
HgeneSCMH1chr1:41578955chr8:42761316ENST00000456518-19134_2350481.0RepeatNote=MBT 2
HgeneSCMH1chr1:41578955chr8:42761316ENST00000456518-1928_1260481.0RepeatNote=MBT 1
TgeneHOOK3chr1:41578955chr8:42761316ENST0000030760202210_12619.0719.0DomainCalponin-homology (CH)


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Fusion Gene Sequence for SCMH1-HOOK3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000397174_ENST00000307602_TCGA-HB-A5W3-01A_SCMH1_chr1_41578955_-_HOOK3_chr8_42761316_length(transcript)=15225nt_BP=1084nt
TGATAGACTGGAGTGATGTTAGAAAACACAAATATGGTCACCTATCAGAGTCTGCATCCCAATATCAAGAAGCTGCTGACATCCTGGATC
TAGGGTTGTAAAGAAGATTACATGAGCTAATGGATGTGAAAACATCTTAAAAACTCTCAAATACTTTTCAACTTTGGAGGATTATTATGA
TTTTCATTCTGTTCAGCGGCTATACTCAGACTTTACTCTAAAAGTCAAATCTTCTGACATTCTTTGAAGTGAAGCATTCTATGAATGTGA
GCTGAAGAAATGAATGAAATGAAATAATGCAGCATCTAGTGCTTTTTGCATGGCCCAAAGGGGCTCTGTGCTGCTCCACTACAGAGGAAA
CTTCAAGAAATGCTGGTTTGCTACAGTGTTTTAGCTTGTGAGATTCTCTGGGACCTTCCCTGCTCCATCATGGGGTCACCTCTAGGTCAT
TTTACCTGGGACAAATACCTAAAAGAAACATGTTCAGTCCCAGCGCCTGTCCATTGCTTCAAGCAGTCCTACACACCTCCAAGCAACGAG
TTCAAGATCAGTATGAAATTGGAAGCACAGGACCCCAGGAACACCACATCCACCTGTATTGCCACAGTAGTTGGACTGACAGGTGCCCGC
CTTCGCCTGCGCCTTGATGGGAGCGACAACAAAAATGACTTCTGGCGGCTGGTTGACTCAGCTGAAATCCAGCCTATTGGGAACTGTGAA
AAGAATGGGGGTATGCTACAGCCACCTCTTGGATTTCGGCTGAATGCGTCTTCTTGGCCCATGTTCCTTTTGAAGACGCTAAATGGAGCA
GAGATGGCTCCCATCAGGATTTTCCACAAGGAGCCACCATCGCCTTCCCACAACTTCTTCAAAATGGGAATGAAGCTAGAAGCTGTGGAC
AGGAAGAACCCTCATTTCATTTGCCCAGCCACTATTGGGGAGGTTCGGGGCTCAGAGGTGCTTGTCACTTTTGATGGGTGGCGAGGGGCC
TTTGACTACTGGTGCCGCTTCGACTCCCGAGACATCTTCCCTGTGGGCTGGTGTTCCTTGACTGGAGACAACCTGCAGCCTCCTGGCACC
AAAGATCCAGACATTTAATGTGGATGCACCATGCCAGACCGTGGAAGATTTAACGAATGGGGTTGTGATGGCCCAGGTTCTTCAAAAGAT
AGATCCTGCATATTTTGATGAAAATTGGCTAAACAGAATCAAAACTGAAGTAGGAGATAATTGGAGGCTAAAGATAAGCAATTTAAAGAA
AATTTTAAAAGGAATCTTGGATTATAATCATGAGATTTTAGGACAGCAAATTAATGACTTTACCCTTCCTGATGTGAACCTTATTGGGGA
GCATTCTGATGCAGCAGAGCTTGGAAGGATGCTTCAGCTCATCTTAGGCTGTGCTGTGAACTGTGAACAGAAGCAAGAGTACATCCAAGC
CATTATGATGATGGAGGAATCTGTTCAACATGTTGTCATGACAGCCATTCAAGAGCTGATGAGTAAAGAATCTCCTGTCTCTGCTGGAAA
TGATGCCTATGTTGACCTTGATCGTCAGCTGAAGAAAACTACAGAGGAACTAAATGAAGCTTTGTCAGCAAAGGAAGAAATTGCTCAAAG
ATGCCATGAACTGGATATGCAGGTTGCAGCATTGCAGGAAGAGAAAAGTAGTTTGTTGGCAGAGAATCAGGTATTAATGGAAAGACTCAA
TCAATCTGATTCTATAGAAGACCCTAACAGTCCAGCAGGAAGAAGGCATTTGCAGCTCCAGACTCAATTAGAACAGCTCCAAGAAGAAAC
ATTCAGACTAGAAGCAGCCAAAGATGATTATCGAATACGTTGTGAAGAGTTAGAAAAGGAGATCTCTGAACTTCGGCAACAGAATGATGA
ACTGACCACTTTGGCAGATGAAGCTCAGTCTCTGAAAGATGAGATCGACGTGCTGAGACATTCTTCTGATAAAGTATCTAAACTAGAAGG
TCAAGTAGAATCTTATAAAAAGAAGCTAGAAGACCTTGGTGATTTAAGGCGGCAGGTTAAACTCTTAGAAGAGAAGAATACCATGTATAT
GCAGAATACTGTCAGTCTAGAGGAAGAGTTAAGAAAGGCCAACGCAGCGCGAAGTCAACTTGAAACCTACAAGAGACAGGTAGTAGAACT
ACAAAACAGATTATCCGAAGAATCAAAGAAAGCAGATAAACTAGATTTTGAATATAAGCGGCTAAAAGAAAAAGTTGACAGTCTTCAAAA
AGAAAAGGACAGGCTGAGAACAGAAAGGGATTCTCTGAAGGAAACCATTGAAGAGCTTCGTTGTGTACAAGCTCAAGAAGGGCAGCTCAC
AACACAAGGGTTAATGCCTCTTGGAAGTCAGGAGTCTTCAGACAGTCTAGCTGCAGAGATTGTTACACCTGAAATCAGGGAGAAACTTAT
TCGTCTTCAGCATGAGAATAAGATGTTAAAGCTTAACCAAGAAGGTTCGGACAATGAAAAAATAGCCTTATTGCAGAGCCTTCTAGATGA
TGCAAATCTACGCAAGAATGAACTGGAGACAGAGAATAGGCTGGTGAATCAAAGACTTCTGGAAGTACAGTCACAAGTTGAAGAATTACA
AAAATCTTTACAGGATCAAGGCTCAAAAGCAGAAGATTCAGTCCTTCTAAAAAAGAAGCTTGAAGAACATCTAGAGAAGCTGCATGAGGC
CAATAATGAACTACAGAAGAAGAGAGCCATTATTGAAGATCTCGAGCCAAGATTTAACAACAGCTCCTTAAAAATTGAAGAATTACAAGA
AGCTTTACGAAAGAAAGAGGAAGAAATGAAGCAAATGGAAGAACGATACAAAAAATACTTAGAGAAAGCCAAAAGTGTCATCCGTACTTT
AGATCCTAAACAGAATCAAGGAGCAGCACCAGAAATACAAGCTCTTAAAAATCAGCTCCAGGAACGAGACCGACTGTTCCACTCATTAGA
GAAAGAATATGAGAAAACAAAGAGTCAGAGAGAGATGGAAGAGAAATATATTGTTAGTGCCTGGTACAATATGGGAATGACCCTGCATAA
AAAGGCAGCTGAAGATAGACTGGCAAGCACAGGCTCAGGGCAGTCATTTCTGGCGAGGCAGAGGCAAGCGACCAGCAGCAGAAGATCATA
CCCAGGCCACGTGCAGCCGGCCACAGCAAGGTAGAGAAGTTGTGCCGCTCAATCACAGACACCTGCACCCACAACATACTTCTGTTACAC
ACAAGAACATTTCAGGAAACTCAGCCAGCTTATTTTTTGTTTCTCTTCTATGTCAATACTTAGTGTTTCTCATTTTGAGGACTTTTTCTC
TCTCCTGTATCTTTGTTTTAGTTTCTTTGGTTTTTATTTTGTAGTCCTTTCAGTTATTTTTAATGTGCCAAAAATTTGTACATGTTCAAT
TAAAAATGTTGTATAATAGTGTAATACTTTTCTTTGTATGAAAATGTCCTCTTCTTCAAAGGTATAGGCTTTGTAATGAATTAGATTTTC
TGCCAATAATTGATATACAATTTATATTCTTTATTGTGCCTGTGTGTTACCATGCTAAGAATGTCTTTGTTTAAAGGGAATTAATCTTTT
TATGATGTATTAATCTGTGTTTTCAATTGTTTTCCAAGTACAGTTCAAATAACTTGCATATTTACTATACAAAATGGTTGACAAGTGTTC
TTTTTGCAAAGACTTGAATACATTGGCAGAGGTGCTAATCACATCTTCCCTAAGGCACCTGGAAGAATTATTTGAGGAAAAAATGAGTTT
TCACATTGTTTTATAGGAAATTAAATTTGTCCAAAGATTTGGAGACTATTTTTAAAACATAAATACATAAAATTTCATTATTTCCTGCTA
TCTTGTTTGCTGGCAGAAGTGAATGTTTGGTGAGGTTATTTTGGGATAAATTACAAAAGAAAAAAAATTAGACACTGCATTAATTTCTTG
TTCTTTTGGAATATCTTAGTAACTGAGGATCATTTTCTAACAATGTGGTTGACATACCTTCAGTTGCTTTCCACATCTAAAAGAGTTATC
TTTCATATATGTACAAGTTATTGGTAGTCTTATTTTTGGGCTGTTTGTTGACTTATGCCCCATTTGTTTTACTTGTTCTTTAATATAAAC
CCTTCCATTTTTTAACAATTCCTAACACTTGATATCTTAATATCAGTCACTAACATTAGTAACTTCTTGTATGTTATATTATGGCAGATC
TCTTTACGTTTTTTCTCACATCTATCTGCTAGTCCAGGAATTTGTTACTAAATAGATTTTCTTGGATATTTGGTTGCCTCAAAGTGCTTA
CATTTGTTAACAGATTGTAAACCACATTTATTTACATTGATGAATGGGCTGTTGAATAATCATTGTAAAGCACTTTGTATATATAAGGTG
CTATATAAGTGTGAAATATCATTCATTTATAAATGAAATGCCTTCTAACTTTCCATATTGACTTATGTATTTGGTCCCAAATTATATTTA
AGTCTTTTTTCTTGCAACGTAGCCCATTTTTTGAAAGCAAAACATTTCTGAAATTAGGTCATGGTTTTTTTGTTTATTTTTAGGTTAGGT
CACTTAATATAGGAGGATGTTTTCTCATGTACTTGCTATTTGCAAGTTCAGGTTTCATTTGGTTCTTTATGTTAAATACGAATAAGTAAC
CTCAAATCAAGCTAAATGTAATTAAGAATTTTCAGCAACTATATTCAAGTGTTTGATTTTTAAATTCTTTCTTTCTTTTTAATAAGAAAG
ATGACCTAAAAATCAGTGGTATTTGTTTGTCCTCAGAAGCCGTAGTTGAAGAAAGATATTAGAGTATACACAGAACTGGAGCCATACATT
GTGCTAATTTTTTACATTAAGTACAGAAGTCTGAGCACAGCATGAATGCTTCTGCCTGACAGGACCACAAAGCAGCAGAAGTTAGGGATA
AATGGAGATAGCCATGAGTAGAACTGCTGTAGGGCTTCAGGAGGCTACGCAGACCTGATCAACTGCAAAGTTTCCAAAGTAAAAGATTAA
AAACTTTCAGACGGTTCTTACCTCTACCCGTGTTTCACAAATAGCCTGAGGATCCAACTATTTTTAAAGCAAATTGGGGCCAGACGTGGT
GCCTCACGCCTGCAATCTCACCATTTGGGAGACCTAGGTGGGGGTGGATCACTTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGG
TGAAACCCCATCTCTACTAAATTACAAAAATTAGCTGGGCATGGTGGCATGTGGCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAG
AGTCACTTGAACTCAGGAGCCAGAGACTGCAGTGAGCTGAGATCGCACCACTGCATTCCAGCCTGGGCGACAGAGTGAGACTCTGTCTCA
ATCAGTCAATCAATCAATCAATCAAATTGGAATATGAGCACTAACCTTGGTAAGTTAAAATTTTGGGAAAATTGTACCTGCAGAATATGA
TGGATGAAAACAACAGCCAGGTGCAGTGGCTCACGCGTATAATCCCAGCACTTTGGGAGGCCGAGACAGGCACATCATCTGAGGTCAGGA
CTTCCAGACCAGCCTGTCCAACATGGTGAAACTCCGTCTCTACTAAAAATACAAACAATTAGCCAGGCATGGTGGTGTGTGCCTGTAGTC
CCAGCTACTTGGGAGGGTGAGGCAGGAGAATTGCTTGAACCTGGGAGACAGAGATTGCAGTGAGCCGAGATGGCGCCATTGCACCCCAGC
CTGGCGACAAGAGCGAAACTCTGTCGCAAGAAAAAAAAAAAAAAAAAAAAAAAAAAAAACAGTCTGTGAACTACTCACTGAATGAATTTT
GTTCTGTGAGATGAGAGGTTTTCATTTTCATTTTCTATTTACAGCCCCAGTCCTAATCTCCTACCCATCCACCTACCCAGATATTTTTTC
TCTATCTGGGTTGGAAAGGCCCCAGGCTTTTAGAGGGGAGTTTTACTTCTGACTTTTTTTTCCCCCCGAGACGGAGCCTCGTTCCGTCAC
CCAGGCTGTAGTGCCGTGGCATGATCTCGGCTCACTGCAGCCTCTGCCTCCCGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCAGAGTAG
CTGGGATTACAGGTGCCCACCACCATGGCTGGCTAATTTTTGTAATTTAGTAGAGATGGTGTTTCACCATGTTGGCCAGGCTGGTCTCAA
ACTCCTGACCTCGTGATCTACCCACCTCGGCCTCCCAAAGTGCTGAGATTACAGGCACGAGCCACCGCGCCCAGTCGTACTTCTGACTTT
TCTTCAGCATCTGTTGTATGCTATTATTTTGATGTTTACATTTATAATTTTCTTTCTTTTTTTTTTTTTTGTGAGATGATGTCTCGCTCT
GTCACCCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCTG
AGTAGCGGGGACTACAGGCGCCCGCCACTACGCCCGACTAATTTTTTGTATTTTTTAGTAGAGACGGGGTTTCACCATGTTAGCCAGGAT
GGTCTCGATCTCCTGACCTCGTGATCCACCCGCCTCAGCCTCCCAGAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCAGCCTACATT
TATAATTTTCATTCTCTTTTACCTATAAAATTCAGTGTATTAGTTTCATTACATAGGAGAAATTATATTTCTAAACATTTTATGATGTTT
AAAAACAAAACAGGCTGTTGTAAAAAAAAAAAAAAAAAAAACTTCTGAATATACTTTAGGTATCAGAAAGCCAAGAATAAAATTTAGCTC
TAACGGTGGCAACTCCATGTCCGGTGTCCAGCTTTGGACAGGGTTTATGACGTTTCTGTTTCTCTAGTAATGATTAATGATTCCTCAGGA
GATTCGTGATGTTGTCTGGTCTATCTGGAAATTTAAAGTCACTAGGAGCTTTGCCTCATCGTGAGTGATGCTGTGCTGTATTTTTACAAA
CTCTCGCATACAGCACCTTCCTGGGGCCACGTTGGCTTGTGCAGTGGAGCTTGTCCAGGCACCAGCATGGAGCAAGTACAGGGTTGCTGT
GTTGGGTTGGAGCACACTGTCACCACAGTGTCTGAAGTCTTATAAACAGGAAGATCATTTTCTGTTTTCCTTCTAACCAGGGTGAGAAAA
TACAAAGTAAAGAACTAAAGAATATTAAAACCTAGCATTTATGTTCCACAGTGTGTATTTCAGAAGTTTGTAATCCAGAAAATATAGTAG
TGTATAATATCTGAAAAGAGAATCAAGTATACAATTGTACATATTTTTAAAGAACTTTGAAAAACTCCGTCATATCTTTTACCATTTGTC
TATTTGATAGTAATGCAGAAAAAAGTCCCTAAAGACCCTGTGTTCCAAAATTTACCAAGATTGACATTTCTATTAGACATCCTTAACCTA
AGTGTTTTAATTAGATTATTAGACTATAATAAGGATGAAATTGCTGTCTGTAATTTTGTTGAGGTTTTATTGTTAATATAATAAAAGCTC
AACTGTACAAAATTAAGCTAAATGTTATCCAGTCAGAAACATCAGCCTGTGGCCAGGTGCGGTGGCTCACGCCTGTAATCCCAGCACTTT
GGGAGGCCAAGGCAGGCGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCTAATATGGTGAAACCCCATCTCTACTAAAAATACAG
TATTAGCCAGGCATGGTGGCAGGCGCCTGTGATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCATGTGAACCCAGGAGGTGGAGGTT
GCAGTAAGCCGAGATTGTGCCACTGCACTCCAGCCTGGGCCACAGAGTGAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAAAAGAAACA
TCAGCCTGTATATTCCAGTAGTTCTCACAGAAGAATGAAAATCCGTGCTGTGCAAATAGATCAGTAGTGAGTGAGTGTTAAGTGAAAGAT
GAGCTAGGTTGAAGAAAATATACATTTTATTGATGAGCCACTTTGCTATCTCTCCTTCCTTCCTCCTTCCTTCCTTCCTTCCTTCCTTCC
TTCCTTCCCTTCTTTTCTTTTTTCTTTTCTTTTCTTTTCTCCCTCCTTTCTTCCTTCCCTTCCCTTCCCCTCCCCTCCCCCAGGCTGGAG
TGCAGAGGCACGATCCTGGCTGACTGCAAACTCTGCCTACCAGGTTCAAGCGATTCTCCTGCCTCATCCTCCCTAGTAGCTAGGATTACA
GGCATCTGCCACCACGCCCAGCTAATTTTTGTATTTTTACAAAATACAAAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCTAAC
TCCTGACCTCAGGTGATCCGTCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGTGTTACTGCCCCAGCCTCCTATTTCCTTTTC
GAAAGTAGCAGTTTGGTTTATTCTCGTTTGCTAAGTAATTGTTTGAAATATTTTTCAGCCTCTCCTGCTCCCTCACAAAAATTCACCTGT
CATTTTAATGATAACAGCATGTTAAAAACTTGGAAGTCTTTATCCCAATATAAGAATTATCTTGAAACAAAAATCTAAATTACTTTTAAA
AATTCTCTTAACTCTGCATTTAGTCTCCTATTATCTAGATCTCTGAGTCCAGGATAACTCCAGTTATCCCCAGTTGGATCATGTGTGATT
TATCTGAGAAAGCATCCACAACCCACAGCTAGTGGAAACCGAGCTAGTTTACAGCCACGTGGATAAGAACATCTTTGTTTCTAAAGTGAG
AGGAAAGTGCTTGGTATCTTGCTTTTTGCTGAGGGCAAAATAACAACATGAAGACAAAGTGCTTTTTGTTGTCTATTCATGAAACTGTAG
AAGAATATTTTGAGTTTTTATTCTTATATTATGAAGGGATTCTTTGCCTAGCAGTGGCCGTCAAACTGATGTAGCATTGTACTTCTCAAC
AGTGAAGCCTGTGTAATACCATACAGTAGGATGAAAGACTATTCTGAGCAAAATCAAATGGGATGTCAGAATCTTTGAAAATTATTTTAT
CATTTTTTCTATTTTTTCATTTTTATAAATTAGAAGGATTTTCCATTCAATAAGGATAATCTCTCTTCCTATCATTCTGTCAAAATGGCA
GTTTCTTTTGGTAATTATCCAACCTAGTTTCATTACATTTAGAAGGAGGTTTCAGAGCTTATTCTTGATAACTATAATAATGATTTGAAT
GTTTTATATCATGAAGTTTTTTCTATGAGGAAGGCTATTCTCAATGTATCTGTCGTCTAATTTTTTATTTTCTATCTATAAAGAATATTT
AAATAATAATTGGTGTATGTTCCTTTTGTTGAAAATGTTTTATTGTCCAGTTTTAACACAGAAGTGGTCTAAAGTTTTGCAGCAAATGCT
GTTCAGTTCCCAGAAGCCTAAAAAACATAACATAATATGCTAACAGAGCTAATTTCCACCCAATCCCTCAAATTACCGAAGTATTAATAT
TTAGCTTCCTTTCTAGAAAACAAGGGGCAGCACAAATGGGGTGGCATCCATCTCTTTTAAATCACTGATGATTTTCTGGGGAAGTATATA
TAGATGATTTTATTTTTTAAATAGCCTTTTATCAAACCATTTCACATGTATTATCTATATGACTATAGAAACTTATAAAACATTTAATTC
ATGTTGACTTAAAACATGGGCATCCTTGGATTCTCCACATTGACTGAAATGATAGAGAAAGGGACATTTGTTTGAGAAACAAGAGACCTG
TACCTAATTATGGCAAGTATATGAGTTTTGGTGATTGTGGGGGGTTATAAATGTTTTCCTATGATAGATAAATATATAGATATAGATCAG
GAATTACTTGATGTCTCTTCAGAAGTTTTCTGTTTTCTTATAATTTCCAGTAATACTCTGTAAGACTCGGTTTGCATGCTGTGTGTGTTT
GCATGAGTATAGAAACCTAAGAACATAATGGAAGGCTATTAAGGCAAATTCATTCCTAGAAAGTGGAGTGGATCATTGGGATAAGAAATA
GCCTAATTATAAACAAATATGCAGGCAGAGGGAAGTCCTAATACAATGAAAACTTGCATTATCTAAACAGATGTTCCCAAAGCAATAGTT
TGCCTAAAATCCTCTGTATTACATGATTATTCAGTAAAAGAGTAAACAAATATCTAATTTATTTTCTAATTGTCCTTCCCTTCATTGAGT
ATTAACTAGGTGCATAATGTAGTTGTATATGTTTACTAGTAAAGGGAAAAACACTTATTTTCATTTTGAGACTGTTTGGCTATTACTAAA
GCTGAGAAAGTGATTTTAGGTCGCCAAGGATACTATGATTTGATGAGATGAGAAGAAATCTGCGGTGGCTGAAAATCGTGACCAACTTGG
TGTTATCTAGATCTGCTTTATCTAGTTTGCAAGCCATAGGCTCAATTTTATGTCCTTCTTACTTACACACAGTAGCCCCACACAGTTTTG
TTTTAAATGAAGGCAAAAGTAGACATTTTTAAAGTATATTCAACATTGTGCCATTATTTACCTGATAAAGGTGAAATCAGAGGTGTCCAC
GGCCTCAAAGTTTGGGCCCATGGGACTATCAAATCCGAATTATATCTACTTAGAGCTTAGAGGAAGAATTAGGTATCATGAGAAAAGCAA
CTCCTACTTGAGAGAAAGAAGACTACCAAAGCATGTTGAGGCTTTAACATGGGAGACTTCCAGGTAGGCGTTAACACTTGAGTGGTAACT
AGCTTGATGAAGGAAAATAATTACTTTAGCAGTTATGTTGTAAAATTAATAAAAAGGACTCATGTTTATTCTGGTGTATTTGTCAACCCA
TGGGTAGTGATTACTCCGTGTACATTCTATAGTGTGTGTATTTTATTTAGTGTCTTAATATATAGTCTTTATATAGTATCTTAATATTAT
TTACTGTTACTTCTAGTCATTTATGTAGTATATTTTACTGCAAAATTTGTAGCACTTTACTAATATTAGATCATTATTTTCCCTCTTCCC
CTCTACCTTTCTGGCATTTTCTGTTATCTTAGAGTCAGGAATCTAAAGGTCTAAGTCTAGAAATCTGTTGGAAGCTGGGTTGGAGCTACT
GGATATGAGTTACTTTTTACATGTCTCCTTAAGAAGACTCTTTTATAATGTAATACTTAGAAGCCAAATCCTTTCAAACGCAAACACCCT
TGAAACTTGATGCTTTCTGAAGTTGTATTCATAAAAATTATCCCATCTTACAGTTAATCAGAAGATGTTCTTACCTTTGGTTTGCCTGCC
TCCTGAAACACAAACCTGCAGATTGCCCCTAACTTCAGCAGTGCCTCCGTCACTGCATGTACCTAAAAGACAGGAAAGCCAAGTTCTGGG
AGCTGTCAAGTCGGAGGATCAGGAAAATGGTGGGGAAGAGGTGACTGGAAAGGCAGGCACTAAAGATGGCAGGCTGCAAAAGCATTCTGA
GTTCCCCTGTAACAGATAGGTTTTATGAACTCAGCTGTTTTCTTTTTTCTTTTTTTTTCTTTTGAGATGGAGTCTCACTCTGAGTCTCAC
TCTGTTGCCCAGGCTGGAGTGCAGTGGCACAATCTCAGCTCACTGCAGCCTCCACCTCCCGGTTTCAAGTGATTCTCCCACCTCAGCCTC
CCGAGTAGTTAGGATTACAGGTGCCCACCACCACGCCCAACTAATTTTTGTATTTTTAGTAAAGACAGGGTGTCGCCATATTGGCTAGGC
TGGTTTTGAACTCCTGACCTCAGGTAATCCACCCGCCTCAGCCTCCCAAAGTGCTGGGATTATTATAGGCGTGAGCCACCATGCCCAGTG
AACTTGGCCATTTTCTTACATTCATATATAGCAAAGTTTTCAACTTGTCTACCGAGAGACTTTCTTTAGGAGCCAGGACTTCTACATTTG
TAACTTGAGTATATTAATATTCAAATCATAGTTCAAAAATACTGAAATACTTGTTTATTATGTTACATAAATATGGACACAATTACTGCC
AAAGAATAGAGAGATTTGCTTATGAGAACATTCTGTCATTTGTTCTGTTTGTAGATGAGAGACATGCTTTTAAAGTACAAAACGTTTCTC
TTCTACCTTACCCCCTGTTCTACTGACGTGCTTTGCATGAGAAGCTCATCTAGAAGAGAGCAACGCTGGAATAGAGAAGTCTAGACCCTG
GCCTTTGAGGGAAAGGACTGCTTTTTTTCTCTCCCAAATTAGAAAATTAAAAGTGAAACATAACACATAAGGACGAAATACAATGTTCTG
AATATCTTCCACTAATTAATTGTTGAATGATTAAGTCTCTAAGTATCTTAACTTCCATTGTCTTCTTGTTAACCTAGACAAGAGTAGATT
ATTCAGTAGCCACATGTGACAGTTAAAATTAAGTAAAATTAAAACTATAGTTTCTCAGTGGCCTAGCCACATTTCAAGTGTTCCACAGTC
ACATGTGGATAGTAGTTACCTATCAGACAGTACAGGTATAGAACATTTCCAGTATTGCCAAAAATGCTATTCAACAGCACTTTTATTGCC
CAGAGAGAAAATAAGGACAAAATAAAGGCAGTGAAGTAACTTAAGACAACTCTGAGATTTTACCACCATACTTAGAGAAAGTTTTTCTGT
TATAAAAATTAATACTAATCCTTTTTAAAGACCTTGGAAAAAATCAAAACCCCATTCCTTTAAGCTAGTCTTCAGTATATATTTTTCTAA
GAACAGATTCTCAATACTTTATTTTTCAAGTGATAAAATCATTTTATAAATCATTTCTTAATATCTTCAGTGTTTTTTCCCTTTTTATGT
AAACTCTTTTAAAATTGATATTAGCTGGGCATGGTAGCTCATGCCTGTAGTCCCAGCTACTCCAGAGGTCGAGGCAGGAGCATCGCTTAA
GCCCAGGAGGTTCAGGCTGCAGTAAGGTCTGATCACACCTGACTGCACTCCAGCCTGGGTGGCAAAGCAAGACCCCTGTCTCTAAAAAAA
AATAATATAAATTGATGTTATATAGTTAACATTTATCAGGCAAATTCATATGAATGCTTATTTCAAATAAAGATTGATAGATTTAATGAT
ATCCTTCCTTTTAAATTTATATAGATCTAATGAACATTGCCAACAGTTTTTTTTGTTTCTGTCCCTTAAACATTTCCCCTGAAAGTCCAC
CTCAAAGGTACATCAAGATGCAAACAATTTTTTTATCTTCATAACTTCCTGCTCTTATTAACTTGTATTATGAATCAAATTAAGTTTTAT
GTATAAGGCATTTACTATTCCAGTGACTTAGCTAATGAAAACATTTAAAAATATGTATTAATTTACTTGGCCTGCTACTAAAGTGCTTAA
CATAACTAAATGGATCTATAGTAACATGTCTAAATTTTTTAATGGAAATAAGGGACTAACCATAATCCTTTTGAGTCAGCTTGGTGCTTA
CAATTATTTTGTTAGGAAATCTTGATGCTTTCTTCTTTCTCTTTAAATTTTTGTAATCAAGCAACAGACTTGATCCAGCAGTGTCGAATT
CCAAGCAAGTTATGATGATTCTTATTGTAGTTCAAGTACAGATGAGTAAGTGGTGTGACTTCAGTTTATTATCTTCTTGGTGACCTACTT
TAGTATGTGTTCTGTAGCGATTCATATTAGTTAAGGGACGTTTTCAATATGCTTGAAATAAGAAATAGCATTTTACTCTAAATACAAGAA
ATGACTGTACACAAATGCTAATCAGTGATTTGGGGCCTTTTAATGTCTTTAACAGCAATCTTTTATTTATTTATTTATTTATTTTTGAGA
CGGAGTCTTGCTGTGTCACCAGGCTGGAGCAGTGGCACGATCTCGCCTCACTGCAACCTCCGCCTCCCAGGTTCAAGCTATTCTCCTGCC
TCAGCCTCCCAAGTAACTGGGACTGCAGGCACATGCCACCACATCCAGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCTTGTT
GGCCAGGATGATCTCGATCTCTTGATCTCGTGATCTGCCCGCATTGGCCTCCTGAAGTGCTGGGATTACAGGCATGAGCCACTGCGCCCG
GCCCAAATCTTTTATTTTTTAACAGCCTTAGTTATTTATAATTCAAATGCACTAAAATATCATCGCTGTCATGAACTTTGCTGTTTACAG
GTTCTGTGTAATTCAGAATGCTTTGTACTTAGAAAATAATTTCTAGGCTTATCTTGTTTTGCAGTTTTCATGTTTTGACAATTGCCCACC
ATTTACAATACTCAATTTTTGATTATGAAATGAATAGTAAAATTCAAACATATCTAATAATAATTTGCCTTAGTTTGATTAATAAATTAT
ATCAAAAAACTTGGGGATAGAAAGAGGCTTTTTTTTCCCCCTGTAGTATTTTTAAAACTTTTTAGATGAGCTGGATGAAACCTTAGTACA
TTGGAGCTGGAGTTGTATTGAGTACAGCCCCAACTCTGAAGCCTTATATTCATGTCTTAAGTACCATTGATTGTTCTGTGAATTGTTGTT
AGTTTCATATTTGACATTGTAGTAATCCACCTTGCATTTTAGTCTTTGCAAAAAGGATATTGCTAGGTATATTCTTATTTCTGATTGAGT
ATTGAATTTACATTTTTCAGAATTTCATTCTTTGTCATTATAATCCAAAAACAATGTCCACATCAGACTTGGAACTTCTCACTTCAAAAA
TGAAATACAGATTTAGCAGTGTTGTACATAATGATGTCCAAGCATTTTTCCACCTGTTTACTGAGTTTTCCAACCATTTACTATGTGTTG
AGATTGGTGGGTTTTCTGGCTGTTTTTCTGAGGTGAATGACTTGTTACAGAGCCTCAGTAAGAAATTTCAACTAAAATCACAAAAACATA
AAGTCCAGGAAACCACCAGAAGATGGATTTTTAGTGTTTTTGAAATCTTGTATTTCCTTTTGATATCATTTACTCATTTTAATTTTACGA
CTGCCAACTTGTTACGGTATTAATTATATGTATGTGTTTATATGTATGCATATAATATATGTATATGTATATGAAGAATAAAGTTAAGAT
TTGGTCAAACTATATTTTCCCATTCAAGTACAAAAATGTTTTCAAGGCTGCAAAAAGTGTACAGTTGTTAAACAAGTTGTAAATAAAGAC

>In-frame_ENST00000397174_ENST00000307602_TCGA-HB-A5W3-01A_SCMH1_chr1_41578955_-_HOOK3_chr8_42761316_length(amino acids)=710AA_start in transcript=1051_stop in transcript=3183
METTCSLLAPKIQTFNVDAPCQTVEDLTNGVVMAQVLQKIDPAYFDENWLNRIKTEVGDNWRLKISNLKKILKGILDYNHEILGQQINDF
TLPDVNLIGEHSDAAELGRMLQLILGCAVNCEQKQEYIQAIMMMEESVQHVVMTAIQELMSKESPVSAGNDAYVDLDRQLKKTTEELNEA
LSAKEEIAQRCHELDMQVAALQEEKSSLLAENQVLMERLNQSDSIEDPNSPAGRRHLQLQTQLEQLQEETFRLEAAKDDYRIRCEELEKE
ISELRQQNDELTTLADEAQSLKDEIDVLRHSSDKVSKLEGQVESYKKKLEDLGDLRRQVKLLEEKNTMYMQNTVSLEEELRKANAARSQL
ETYKRQVVELQNRLSEESKKADKLDFEYKRLKEKVDSLQKEKDRLRTERDSLKETIEELRCVQAQEGQLTTQGLMPLGSQESSDSLAAEI
VTPEIREKLIRLQHENKMLKLNQEGSDNEKIALLQSLLDDANLRKNELETENRLVNQRLLEVQSQVEELQKSLQDQGSKAEDSVLLKKKL
EEHLEKLHEANNELQKKRAIIEDLEPRFNNSSLKIEELQEALRKKEEEMKQMEERYKKYLEKAKSVIRTLDPKQNQGAAPEIQALKNQLQ

--------------------------------------------------------------
>In-frame_ENST00000402904_ENST00000307602_TCGA-HB-A5W3-01A_SCMH1_chr1_41578955_-_HOOK3_chr8_42761316_length(transcript)=15225nt_BP=1084nt
TGATAGACTGGAGTGATGTTAGAAAACACAAATATGGTCACCTATCAGAGTCTGCATCCCAATATCAAGAAGCTGCTGACATCCTGGATC
TAGGGTTGTAAAGAAGATTACATGAGCTAATGGATGTGAAAACATCTTAAAAACTCTCAAATACTTTTCAACTTTGGAGGATTATTATGA
TTTTCATTCTGTTCAGCGGCTATACTCAGACTTTACTCTAAAAGTCAAATCTTCTGACATTCTTTGAAGTGAAGCATTCTATGAATGTGA
GCTGAAGAAATGAATGAAATGAAATAATGCAGCATCTAGTGCTTTTTGCATGGCCCAAAGGGGCTCTGTGCTGCTCCACTACAGAGGAAA
CTTCAAGAAATGCTGGTTTGCTACAGTGTTTTAGCTTGTGAGATTCTCTGGGACCTTCCCTGCTCCATCATGGGGTCACCTCTAGGTCAT
TTTACCTGGGACAAATACCTAAAAGAAACATGTTCAGTCCCAGCGCCTGTCCATTGCTTCAAGCAGTCCTACACACCTCCAAGCAACGAG
TTCAAGATCAGTATGAAATTGGAAGCACAGGACCCCAGGAACACCACATCCACCTGTATTGCCACAGTAGTTGGACTGACAGGTGCCCGC
CTTCGCCTGCGCCTTGATGGGAGCGACAACAAAAATGACTTCTGGCGGCTGGTTGACTCAGCTGAAATCCAGCCTATTGGGAACTGTGAA
AAGAATGGGGGTATGCTACAGCCACCTCTTGGATTTCGGCTGAATGCGTCTTCTTGGCCCATGTTCCTTTTGAAGACGCTAAATGGAGCA
GAGATGGCTCCCATCAGGATTTTCCACAAGGAGCCACCATCGCCTTCCCACAACTTCTTCAAAATGGGAATGAAGCTAGAAGCTGTGGAC
AGGAAGAACCCTCATTTCATTTGCCCAGCCACTATTGGGGAGGTTCGGGGCTCAGAGGTGCTTGTCACTTTTGATGGGTGGCGAGGGGCC
TTTGACTACTGGTGCCGCTTCGACTCCCGAGACATCTTCCCTGTGGGCTGGTGTTCCTTGACTGGAGACAACCTGCAGCCTCCTGGCACC
AAAGATCCAGACATTTAATGTGGATGCACCATGCCAGACCGTGGAAGATTTAACGAATGGGGTTGTGATGGCCCAGGTTCTTCAAAAGAT
AGATCCTGCATATTTTGATGAAAATTGGCTAAACAGAATCAAAACTGAAGTAGGAGATAATTGGAGGCTAAAGATAAGCAATTTAAAGAA
AATTTTAAAAGGAATCTTGGATTATAATCATGAGATTTTAGGACAGCAAATTAATGACTTTACCCTTCCTGATGTGAACCTTATTGGGGA
GCATTCTGATGCAGCAGAGCTTGGAAGGATGCTTCAGCTCATCTTAGGCTGTGCTGTGAACTGTGAACAGAAGCAAGAGTACATCCAAGC
CATTATGATGATGGAGGAATCTGTTCAACATGTTGTCATGACAGCCATTCAAGAGCTGATGAGTAAAGAATCTCCTGTCTCTGCTGGAAA
TGATGCCTATGTTGACCTTGATCGTCAGCTGAAGAAAACTACAGAGGAACTAAATGAAGCTTTGTCAGCAAAGGAAGAAATTGCTCAAAG
ATGCCATGAACTGGATATGCAGGTTGCAGCATTGCAGGAAGAGAAAAGTAGTTTGTTGGCAGAGAATCAGGTATTAATGGAAAGACTCAA
TCAATCTGATTCTATAGAAGACCCTAACAGTCCAGCAGGAAGAAGGCATTTGCAGCTCCAGACTCAATTAGAACAGCTCCAAGAAGAAAC
ATTCAGACTAGAAGCAGCCAAAGATGATTATCGAATACGTTGTGAAGAGTTAGAAAAGGAGATCTCTGAACTTCGGCAACAGAATGATGA
ACTGACCACTTTGGCAGATGAAGCTCAGTCTCTGAAAGATGAGATCGACGTGCTGAGACATTCTTCTGATAAAGTATCTAAACTAGAAGG
TCAAGTAGAATCTTATAAAAAGAAGCTAGAAGACCTTGGTGATTTAAGGCGGCAGGTTAAACTCTTAGAAGAGAAGAATACCATGTATAT
GCAGAATACTGTCAGTCTAGAGGAAGAGTTAAGAAAGGCCAACGCAGCGCGAAGTCAACTTGAAACCTACAAGAGACAGGTAGTAGAACT
ACAAAACAGATTATCCGAAGAATCAAAGAAAGCAGATAAACTAGATTTTGAATATAAGCGGCTAAAAGAAAAAGTTGACAGTCTTCAAAA
AGAAAAGGACAGGCTGAGAACAGAAAGGGATTCTCTGAAGGAAACCATTGAAGAGCTTCGTTGTGTACAAGCTCAAGAAGGGCAGCTCAC
AACACAAGGGTTAATGCCTCTTGGAAGTCAGGAGTCTTCAGACAGTCTAGCTGCAGAGATTGTTACACCTGAAATCAGGGAGAAACTTAT
TCGTCTTCAGCATGAGAATAAGATGTTAAAGCTTAACCAAGAAGGTTCGGACAATGAAAAAATAGCCTTATTGCAGAGCCTTCTAGATGA
TGCAAATCTACGCAAGAATGAACTGGAGACAGAGAATAGGCTGGTGAATCAAAGACTTCTGGAAGTACAGTCACAAGTTGAAGAATTACA
AAAATCTTTACAGGATCAAGGCTCAAAAGCAGAAGATTCAGTCCTTCTAAAAAAGAAGCTTGAAGAACATCTAGAGAAGCTGCATGAGGC
CAATAATGAACTACAGAAGAAGAGAGCCATTATTGAAGATCTCGAGCCAAGATTTAACAACAGCTCCTTAAAAATTGAAGAATTACAAGA
AGCTTTACGAAAGAAAGAGGAAGAAATGAAGCAAATGGAAGAACGATACAAAAAATACTTAGAGAAAGCCAAAAGTGTCATCCGTACTTT
AGATCCTAAACAGAATCAAGGAGCAGCACCAGAAATACAAGCTCTTAAAAATCAGCTCCAGGAACGAGACCGACTGTTCCACTCATTAGA
GAAAGAATATGAGAAAACAAAGAGTCAGAGAGAGATGGAAGAGAAATATATTGTTAGTGCCTGGTACAATATGGGAATGACCCTGCATAA
AAAGGCAGCTGAAGATAGACTGGCAAGCACAGGCTCAGGGCAGTCATTTCTGGCGAGGCAGAGGCAAGCGACCAGCAGCAGAAGATCATA
CCCAGGCCACGTGCAGCCGGCCACAGCAAGGTAGAGAAGTTGTGCCGCTCAATCACAGACACCTGCACCCACAACATACTTCTGTTACAC
ACAAGAACATTTCAGGAAACTCAGCCAGCTTATTTTTTGTTTCTCTTCTATGTCAATACTTAGTGTTTCTCATTTTGAGGACTTTTTCTC
TCTCCTGTATCTTTGTTTTAGTTTCTTTGGTTTTTATTTTGTAGTCCTTTCAGTTATTTTTAATGTGCCAAAAATTTGTACATGTTCAAT
TAAAAATGTTGTATAATAGTGTAATACTTTTCTTTGTATGAAAATGTCCTCTTCTTCAAAGGTATAGGCTTTGTAATGAATTAGATTTTC
TGCCAATAATTGATATACAATTTATATTCTTTATTGTGCCTGTGTGTTACCATGCTAAGAATGTCTTTGTTTAAAGGGAATTAATCTTTT
TATGATGTATTAATCTGTGTTTTCAATTGTTTTCCAAGTACAGTTCAAATAACTTGCATATTTACTATACAAAATGGTTGACAAGTGTTC
TTTTTGCAAAGACTTGAATACATTGGCAGAGGTGCTAATCACATCTTCCCTAAGGCACCTGGAAGAATTATTTGAGGAAAAAATGAGTTT
TCACATTGTTTTATAGGAAATTAAATTTGTCCAAAGATTTGGAGACTATTTTTAAAACATAAATACATAAAATTTCATTATTTCCTGCTA
TCTTGTTTGCTGGCAGAAGTGAATGTTTGGTGAGGTTATTTTGGGATAAATTACAAAAGAAAAAAAATTAGACACTGCATTAATTTCTTG
TTCTTTTGGAATATCTTAGTAACTGAGGATCATTTTCTAACAATGTGGTTGACATACCTTCAGTTGCTTTCCACATCTAAAAGAGTTATC
TTTCATATATGTACAAGTTATTGGTAGTCTTATTTTTGGGCTGTTTGTTGACTTATGCCCCATTTGTTTTACTTGTTCTTTAATATAAAC
CCTTCCATTTTTTAACAATTCCTAACACTTGATATCTTAATATCAGTCACTAACATTAGTAACTTCTTGTATGTTATATTATGGCAGATC
TCTTTACGTTTTTTCTCACATCTATCTGCTAGTCCAGGAATTTGTTACTAAATAGATTTTCTTGGATATTTGGTTGCCTCAAAGTGCTTA
CATTTGTTAACAGATTGTAAACCACATTTATTTACATTGATGAATGGGCTGTTGAATAATCATTGTAAAGCACTTTGTATATATAAGGTG
CTATATAAGTGTGAAATATCATTCATTTATAAATGAAATGCCTTCTAACTTTCCATATTGACTTATGTATTTGGTCCCAAATTATATTTA
AGTCTTTTTTCTTGCAACGTAGCCCATTTTTTGAAAGCAAAACATTTCTGAAATTAGGTCATGGTTTTTTTGTTTATTTTTAGGTTAGGT
CACTTAATATAGGAGGATGTTTTCTCATGTACTTGCTATTTGCAAGTTCAGGTTTCATTTGGTTCTTTATGTTAAATACGAATAAGTAAC
CTCAAATCAAGCTAAATGTAATTAAGAATTTTCAGCAACTATATTCAAGTGTTTGATTTTTAAATTCTTTCTTTCTTTTTAATAAGAAAG
ATGACCTAAAAATCAGTGGTATTTGTTTGTCCTCAGAAGCCGTAGTTGAAGAAAGATATTAGAGTATACACAGAACTGGAGCCATACATT
GTGCTAATTTTTTACATTAAGTACAGAAGTCTGAGCACAGCATGAATGCTTCTGCCTGACAGGACCACAAAGCAGCAGAAGTTAGGGATA
AATGGAGATAGCCATGAGTAGAACTGCTGTAGGGCTTCAGGAGGCTACGCAGACCTGATCAACTGCAAAGTTTCCAAAGTAAAAGATTAA
AAACTTTCAGACGGTTCTTACCTCTACCCGTGTTTCACAAATAGCCTGAGGATCCAACTATTTTTAAAGCAAATTGGGGCCAGACGTGGT
GCCTCACGCCTGCAATCTCACCATTTGGGAGACCTAGGTGGGGGTGGATCACTTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGG
TGAAACCCCATCTCTACTAAATTACAAAAATTAGCTGGGCATGGTGGCATGTGGCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAG
AGTCACTTGAACTCAGGAGCCAGAGACTGCAGTGAGCTGAGATCGCACCACTGCATTCCAGCCTGGGCGACAGAGTGAGACTCTGTCTCA
ATCAGTCAATCAATCAATCAATCAAATTGGAATATGAGCACTAACCTTGGTAAGTTAAAATTTTGGGAAAATTGTACCTGCAGAATATGA
TGGATGAAAACAACAGCCAGGTGCAGTGGCTCACGCGTATAATCCCAGCACTTTGGGAGGCCGAGACAGGCACATCATCTGAGGTCAGGA
CTTCCAGACCAGCCTGTCCAACATGGTGAAACTCCGTCTCTACTAAAAATACAAACAATTAGCCAGGCATGGTGGTGTGTGCCTGTAGTC
CCAGCTACTTGGGAGGGTGAGGCAGGAGAATTGCTTGAACCTGGGAGACAGAGATTGCAGTGAGCCGAGATGGCGCCATTGCACCCCAGC
CTGGCGACAAGAGCGAAACTCTGTCGCAAGAAAAAAAAAAAAAAAAAAAAAAAAAAAAACAGTCTGTGAACTACTCACTGAATGAATTTT
GTTCTGTGAGATGAGAGGTTTTCATTTTCATTTTCTATTTACAGCCCCAGTCCTAATCTCCTACCCATCCACCTACCCAGATATTTTTTC
TCTATCTGGGTTGGAAAGGCCCCAGGCTTTTAGAGGGGAGTTTTACTTCTGACTTTTTTTTCCCCCCGAGACGGAGCCTCGTTCCGTCAC
CCAGGCTGTAGTGCCGTGGCATGATCTCGGCTCACTGCAGCCTCTGCCTCCCGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCAGAGTAG
CTGGGATTACAGGTGCCCACCACCATGGCTGGCTAATTTTTGTAATTTAGTAGAGATGGTGTTTCACCATGTTGGCCAGGCTGGTCTCAA
ACTCCTGACCTCGTGATCTACCCACCTCGGCCTCCCAAAGTGCTGAGATTACAGGCACGAGCCACCGCGCCCAGTCGTACTTCTGACTTT
TCTTCAGCATCTGTTGTATGCTATTATTTTGATGTTTACATTTATAATTTTCTTTCTTTTTTTTTTTTTTGTGAGATGATGTCTCGCTCT
GTCACCCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCTG
AGTAGCGGGGACTACAGGCGCCCGCCACTACGCCCGACTAATTTTTTGTATTTTTTAGTAGAGACGGGGTTTCACCATGTTAGCCAGGAT
GGTCTCGATCTCCTGACCTCGTGATCCACCCGCCTCAGCCTCCCAGAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCAGCCTACATT
TATAATTTTCATTCTCTTTTACCTATAAAATTCAGTGTATTAGTTTCATTACATAGGAGAAATTATATTTCTAAACATTTTATGATGTTT
AAAAACAAAACAGGCTGTTGTAAAAAAAAAAAAAAAAAAAACTTCTGAATATACTTTAGGTATCAGAAAGCCAAGAATAAAATTTAGCTC
TAACGGTGGCAACTCCATGTCCGGTGTCCAGCTTTGGACAGGGTTTATGACGTTTCTGTTTCTCTAGTAATGATTAATGATTCCTCAGGA
GATTCGTGATGTTGTCTGGTCTATCTGGAAATTTAAAGTCACTAGGAGCTTTGCCTCATCGTGAGTGATGCTGTGCTGTATTTTTACAAA
CTCTCGCATACAGCACCTTCCTGGGGCCACGTTGGCTTGTGCAGTGGAGCTTGTCCAGGCACCAGCATGGAGCAAGTACAGGGTTGCTGT
GTTGGGTTGGAGCACACTGTCACCACAGTGTCTGAAGTCTTATAAACAGGAAGATCATTTTCTGTTTTCCTTCTAACCAGGGTGAGAAAA
TACAAAGTAAAGAACTAAAGAATATTAAAACCTAGCATTTATGTTCCACAGTGTGTATTTCAGAAGTTTGTAATCCAGAAAATATAGTAG
TGTATAATATCTGAAAAGAGAATCAAGTATACAATTGTACATATTTTTAAAGAACTTTGAAAAACTCCGTCATATCTTTTACCATTTGTC
TATTTGATAGTAATGCAGAAAAAAGTCCCTAAAGACCCTGTGTTCCAAAATTTACCAAGATTGACATTTCTATTAGACATCCTTAACCTA
AGTGTTTTAATTAGATTATTAGACTATAATAAGGATGAAATTGCTGTCTGTAATTTTGTTGAGGTTTTATTGTTAATATAATAAAAGCTC
AACTGTACAAAATTAAGCTAAATGTTATCCAGTCAGAAACATCAGCCTGTGGCCAGGTGCGGTGGCTCACGCCTGTAATCCCAGCACTTT
GGGAGGCCAAGGCAGGCGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCTAATATGGTGAAACCCCATCTCTACTAAAAATACAG
TATTAGCCAGGCATGGTGGCAGGCGCCTGTGATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCATGTGAACCCAGGAGGTGGAGGTT
GCAGTAAGCCGAGATTGTGCCACTGCACTCCAGCCTGGGCCACAGAGTGAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAAAAGAAACA
TCAGCCTGTATATTCCAGTAGTTCTCACAGAAGAATGAAAATCCGTGCTGTGCAAATAGATCAGTAGTGAGTGAGTGTTAAGTGAAAGAT
GAGCTAGGTTGAAGAAAATATACATTTTATTGATGAGCCACTTTGCTATCTCTCCTTCCTTCCTCCTTCCTTCCTTCCTTCCTTCCTTCC
TTCCTTCCCTTCTTTTCTTTTTTCTTTTCTTTTCTTTTCTCCCTCCTTTCTTCCTTCCCTTCCCTTCCCCTCCCCTCCCCCAGGCTGGAG
TGCAGAGGCACGATCCTGGCTGACTGCAAACTCTGCCTACCAGGTTCAAGCGATTCTCCTGCCTCATCCTCCCTAGTAGCTAGGATTACA
GGCATCTGCCACCACGCCCAGCTAATTTTTGTATTTTTACAAAATACAAAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCTAAC
TCCTGACCTCAGGTGATCCGTCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGTGTTACTGCCCCAGCCTCCTATTTCCTTTTC
GAAAGTAGCAGTTTGGTTTATTCTCGTTTGCTAAGTAATTGTTTGAAATATTTTTCAGCCTCTCCTGCTCCCTCACAAAAATTCACCTGT
CATTTTAATGATAACAGCATGTTAAAAACTTGGAAGTCTTTATCCCAATATAAGAATTATCTTGAAACAAAAATCTAAATTACTTTTAAA
AATTCTCTTAACTCTGCATTTAGTCTCCTATTATCTAGATCTCTGAGTCCAGGATAACTCCAGTTATCCCCAGTTGGATCATGTGTGATT
TATCTGAGAAAGCATCCACAACCCACAGCTAGTGGAAACCGAGCTAGTTTACAGCCACGTGGATAAGAACATCTTTGTTTCTAAAGTGAG
AGGAAAGTGCTTGGTATCTTGCTTTTTGCTGAGGGCAAAATAACAACATGAAGACAAAGTGCTTTTTGTTGTCTATTCATGAAACTGTAG
AAGAATATTTTGAGTTTTTATTCTTATATTATGAAGGGATTCTTTGCCTAGCAGTGGCCGTCAAACTGATGTAGCATTGTACTTCTCAAC
AGTGAAGCCTGTGTAATACCATACAGTAGGATGAAAGACTATTCTGAGCAAAATCAAATGGGATGTCAGAATCTTTGAAAATTATTTTAT
CATTTTTTCTATTTTTTCATTTTTATAAATTAGAAGGATTTTCCATTCAATAAGGATAATCTCTCTTCCTATCATTCTGTCAAAATGGCA
GTTTCTTTTGGTAATTATCCAACCTAGTTTCATTACATTTAGAAGGAGGTTTCAGAGCTTATTCTTGATAACTATAATAATGATTTGAAT
GTTTTATATCATGAAGTTTTTTCTATGAGGAAGGCTATTCTCAATGTATCTGTCGTCTAATTTTTTATTTTCTATCTATAAAGAATATTT
AAATAATAATTGGTGTATGTTCCTTTTGTTGAAAATGTTTTATTGTCCAGTTTTAACACAGAAGTGGTCTAAAGTTTTGCAGCAAATGCT
GTTCAGTTCCCAGAAGCCTAAAAAACATAACATAATATGCTAACAGAGCTAATTTCCACCCAATCCCTCAAATTACCGAAGTATTAATAT
TTAGCTTCCTTTCTAGAAAACAAGGGGCAGCACAAATGGGGTGGCATCCATCTCTTTTAAATCACTGATGATTTTCTGGGGAAGTATATA
TAGATGATTTTATTTTTTAAATAGCCTTTTATCAAACCATTTCACATGTATTATCTATATGACTATAGAAACTTATAAAACATTTAATTC
ATGTTGACTTAAAACATGGGCATCCTTGGATTCTCCACATTGACTGAAATGATAGAGAAAGGGACATTTGTTTGAGAAACAAGAGACCTG
TACCTAATTATGGCAAGTATATGAGTTTTGGTGATTGTGGGGGGTTATAAATGTTTTCCTATGATAGATAAATATATAGATATAGATCAG
GAATTACTTGATGTCTCTTCAGAAGTTTTCTGTTTTCTTATAATTTCCAGTAATACTCTGTAAGACTCGGTTTGCATGCTGTGTGTGTTT
GCATGAGTATAGAAACCTAAGAACATAATGGAAGGCTATTAAGGCAAATTCATTCCTAGAAAGTGGAGTGGATCATTGGGATAAGAAATA
GCCTAATTATAAACAAATATGCAGGCAGAGGGAAGTCCTAATACAATGAAAACTTGCATTATCTAAACAGATGTTCCCAAAGCAATAGTT
TGCCTAAAATCCTCTGTATTACATGATTATTCAGTAAAAGAGTAAACAAATATCTAATTTATTTTCTAATTGTCCTTCCCTTCATTGAGT
ATTAACTAGGTGCATAATGTAGTTGTATATGTTTACTAGTAAAGGGAAAAACACTTATTTTCATTTTGAGACTGTTTGGCTATTACTAAA
GCTGAGAAAGTGATTTTAGGTCGCCAAGGATACTATGATTTGATGAGATGAGAAGAAATCTGCGGTGGCTGAAAATCGTGACCAACTTGG
TGTTATCTAGATCTGCTTTATCTAGTTTGCAAGCCATAGGCTCAATTTTATGTCCTTCTTACTTACACACAGTAGCCCCACACAGTTTTG
TTTTAAATGAAGGCAAAAGTAGACATTTTTAAAGTATATTCAACATTGTGCCATTATTTACCTGATAAAGGTGAAATCAGAGGTGTCCAC
GGCCTCAAAGTTTGGGCCCATGGGACTATCAAATCCGAATTATATCTACTTAGAGCTTAGAGGAAGAATTAGGTATCATGAGAAAAGCAA
CTCCTACTTGAGAGAAAGAAGACTACCAAAGCATGTTGAGGCTTTAACATGGGAGACTTCCAGGTAGGCGTTAACACTTGAGTGGTAACT
AGCTTGATGAAGGAAAATAATTACTTTAGCAGTTATGTTGTAAAATTAATAAAAAGGACTCATGTTTATTCTGGTGTATTTGTCAACCCA
TGGGTAGTGATTACTCCGTGTACATTCTATAGTGTGTGTATTTTATTTAGTGTCTTAATATATAGTCTTTATATAGTATCTTAATATTAT
TTACTGTTACTTCTAGTCATTTATGTAGTATATTTTACTGCAAAATTTGTAGCACTTTACTAATATTAGATCATTATTTTCCCTCTTCCC
CTCTACCTTTCTGGCATTTTCTGTTATCTTAGAGTCAGGAATCTAAAGGTCTAAGTCTAGAAATCTGTTGGAAGCTGGGTTGGAGCTACT
GGATATGAGTTACTTTTTACATGTCTCCTTAAGAAGACTCTTTTATAATGTAATACTTAGAAGCCAAATCCTTTCAAACGCAAACACCCT
TGAAACTTGATGCTTTCTGAAGTTGTATTCATAAAAATTATCCCATCTTACAGTTAATCAGAAGATGTTCTTACCTTTGGTTTGCCTGCC
TCCTGAAACACAAACCTGCAGATTGCCCCTAACTTCAGCAGTGCCTCCGTCACTGCATGTACCTAAAAGACAGGAAAGCCAAGTTCTGGG
AGCTGTCAAGTCGGAGGATCAGGAAAATGGTGGGGAAGAGGTGACTGGAAAGGCAGGCACTAAAGATGGCAGGCTGCAAAAGCATTCTGA
GTTCCCCTGTAACAGATAGGTTTTATGAACTCAGCTGTTTTCTTTTTTCTTTTTTTTTCTTTTGAGATGGAGTCTCACTCTGAGTCTCAC
TCTGTTGCCCAGGCTGGAGTGCAGTGGCACAATCTCAGCTCACTGCAGCCTCCACCTCCCGGTTTCAAGTGATTCTCCCACCTCAGCCTC
CCGAGTAGTTAGGATTACAGGTGCCCACCACCACGCCCAACTAATTTTTGTATTTTTAGTAAAGACAGGGTGTCGCCATATTGGCTAGGC
TGGTTTTGAACTCCTGACCTCAGGTAATCCACCCGCCTCAGCCTCCCAAAGTGCTGGGATTATTATAGGCGTGAGCCACCATGCCCAGTG
AACTTGGCCATTTTCTTACATTCATATATAGCAAAGTTTTCAACTTGTCTACCGAGAGACTTTCTTTAGGAGCCAGGACTTCTACATTTG
TAACTTGAGTATATTAATATTCAAATCATAGTTCAAAAATACTGAAATACTTGTTTATTATGTTACATAAATATGGACACAATTACTGCC
AAAGAATAGAGAGATTTGCTTATGAGAACATTCTGTCATTTGTTCTGTTTGTAGATGAGAGACATGCTTTTAAAGTACAAAACGTTTCTC
TTCTACCTTACCCCCTGTTCTACTGACGTGCTTTGCATGAGAAGCTCATCTAGAAGAGAGCAACGCTGGAATAGAGAAGTCTAGACCCTG
GCCTTTGAGGGAAAGGACTGCTTTTTTTCTCTCCCAAATTAGAAAATTAAAAGTGAAACATAACACATAAGGACGAAATACAATGTTCTG
AATATCTTCCACTAATTAATTGTTGAATGATTAAGTCTCTAAGTATCTTAACTTCCATTGTCTTCTTGTTAACCTAGACAAGAGTAGATT
ATTCAGTAGCCACATGTGACAGTTAAAATTAAGTAAAATTAAAACTATAGTTTCTCAGTGGCCTAGCCACATTTCAAGTGTTCCACAGTC
ACATGTGGATAGTAGTTACCTATCAGACAGTACAGGTATAGAACATTTCCAGTATTGCCAAAAATGCTATTCAACAGCACTTTTATTGCC
CAGAGAGAAAATAAGGACAAAATAAAGGCAGTGAAGTAACTTAAGACAACTCTGAGATTTTACCACCATACTTAGAGAAAGTTTTTCTGT
TATAAAAATTAATACTAATCCTTTTTAAAGACCTTGGAAAAAATCAAAACCCCATTCCTTTAAGCTAGTCTTCAGTATATATTTTTCTAA
GAACAGATTCTCAATACTTTATTTTTCAAGTGATAAAATCATTTTATAAATCATTTCTTAATATCTTCAGTGTTTTTTCCCTTTTTATGT
AAACTCTTTTAAAATTGATATTAGCTGGGCATGGTAGCTCATGCCTGTAGTCCCAGCTACTCCAGAGGTCGAGGCAGGAGCATCGCTTAA
GCCCAGGAGGTTCAGGCTGCAGTAAGGTCTGATCACACCTGACTGCACTCCAGCCTGGGTGGCAAAGCAAGACCCCTGTCTCTAAAAAAA
AATAATATAAATTGATGTTATATAGTTAACATTTATCAGGCAAATTCATATGAATGCTTATTTCAAATAAAGATTGATAGATTTAATGAT
ATCCTTCCTTTTAAATTTATATAGATCTAATGAACATTGCCAACAGTTTTTTTTGTTTCTGTCCCTTAAACATTTCCCCTGAAAGTCCAC
CTCAAAGGTACATCAAGATGCAAACAATTTTTTTATCTTCATAACTTCCTGCTCTTATTAACTTGTATTATGAATCAAATTAAGTTTTAT
GTATAAGGCATTTACTATTCCAGTGACTTAGCTAATGAAAACATTTAAAAATATGTATTAATTTACTTGGCCTGCTACTAAAGTGCTTAA
CATAACTAAATGGATCTATAGTAACATGTCTAAATTTTTTAATGGAAATAAGGGACTAACCATAATCCTTTTGAGTCAGCTTGGTGCTTA
CAATTATTTTGTTAGGAAATCTTGATGCTTTCTTCTTTCTCTTTAAATTTTTGTAATCAAGCAACAGACTTGATCCAGCAGTGTCGAATT
CCAAGCAAGTTATGATGATTCTTATTGTAGTTCAAGTACAGATGAGTAAGTGGTGTGACTTCAGTTTATTATCTTCTTGGTGACCTACTT
TAGTATGTGTTCTGTAGCGATTCATATTAGTTAAGGGACGTTTTCAATATGCTTGAAATAAGAAATAGCATTTTACTCTAAATACAAGAA
ATGACTGTACACAAATGCTAATCAGTGATTTGGGGCCTTTTAATGTCTTTAACAGCAATCTTTTATTTATTTATTTATTTATTTTTGAGA
CGGAGTCTTGCTGTGTCACCAGGCTGGAGCAGTGGCACGATCTCGCCTCACTGCAACCTCCGCCTCCCAGGTTCAAGCTATTCTCCTGCC
TCAGCCTCCCAAGTAACTGGGACTGCAGGCACATGCCACCACATCCAGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCTTGTT
GGCCAGGATGATCTCGATCTCTTGATCTCGTGATCTGCCCGCATTGGCCTCCTGAAGTGCTGGGATTACAGGCATGAGCCACTGCGCCCG
GCCCAAATCTTTTATTTTTTAACAGCCTTAGTTATTTATAATTCAAATGCACTAAAATATCATCGCTGTCATGAACTTTGCTGTTTACAG
GTTCTGTGTAATTCAGAATGCTTTGTACTTAGAAAATAATTTCTAGGCTTATCTTGTTTTGCAGTTTTCATGTTTTGACAATTGCCCACC
ATTTACAATACTCAATTTTTGATTATGAAATGAATAGTAAAATTCAAACATATCTAATAATAATTTGCCTTAGTTTGATTAATAAATTAT
ATCAAAAAACTTGGGGATAGAAAGAGGCTTTTTTTTCCCCCTGTAGTATTTTTAAAACTTTTTAGATGAGCTGGATGAAACCTTAGTACA
TTGGAGCTGGAGTTGTATTGAGTACAGCCCCAACTCTGAAGCCTTATATTCATGTCTTAAGTACCATTGATTGTTCTGTGAATTGTTGTT
AGTTTCATATTTGACATTGTAGTAATCCACCTTGCATTTTAGTCTTTGCAAAAAGGATATTGCTAGGTATATTCTTATTTCTGATTGAGT
ATTGAATTTACATTTTTCAGAATTTCATTCTTTGTCATTATAATCCAAAAACAATGTCCACATCAGACTTGGAACTTCTCACTTCAAAAA
TGAAATACAGATTTAGCAGTGTTGTACATAATGATGTCCAAGCATTTTTCCACCTGTTTACTGAGTTTTCCAACCATTTACTATGTGTTG
AGATTGGTGGGTTTTCTGGCTGTTTTTCTGAGGTGAATGACTTGTTACAGAGCCTCAGTAAGAAATTTCAACTAAAATCACAAAAACATA
AAGTCCAGGAAACCACCAGAAGATGGATTTTTAGTGTTTTTGAAATCTTGTATTTCCTTTTGATATCATTTACTCATTTTAATTTTACGA
CTGCCAACTTGTTACGGTATTAATTATATGTATGTGTTTATATGTATGCATATAATATATGTATATGTATATGAAGAATAAAGTTAAGAT
TTGGTCAAACTATATTTTCCCATTCAAGTACAAAAATGTTTTCAAGGCTGCAAAAAGTGTACAGTTGTTAAACAAGTTGTAAATAAAGAC

>In-frame_ENST00000402904_ENST00000307602_TCGA-HB-A5W3-01A_SCMH1_chr1_41578955_-_HOOK3_chr8_42761316_length(amino acids)=710AA_start in transcript=1051_stop in transcript=3183
METTCSLLAPKIQTFNVDAPCQTVEDLTNGVVMAQVLQKIDPAYFDENWLNRIKTEVGDNWRLKISNLKKILKGILDYNHEILGQQINDF
TLPDVNLIGEHSDAAELGRMLQLILGCAVNCEQKQEYIQAIMMMEESVQHVVMTAIQELMSKESPVSAGNDAYVDLDRQLKKTTEELNEA
LSAKEEIAQRCHELDMQVAALQEEKSSLLAENQVLMERLNQSDSIEDPNSPAGRRHLQLQTQLEQLQEETFRLEAAKDDYRIRCEELEKE
ISELRQQNDELTTLADEAQSLKDEIDVLRHSSDKVSKLEGQVESYKKKLEDLGDLRRQVKLLEEKNTMYMQNTVSLEEELRKANAARSQL
ETYKRQVVELQNRLSEESKKADKLDFEYKRLKEKVDSLQKEKDRLRTERDSLKETIEELRCVQAQEGQLTTQGLMPLGSQESSDSLAAEI
VTPEIREKLIRLQHENKMLKLNQEGSDNEKIALLQSLLDDANLRKNELETENRLVNQRLLEVQSQVEELQKSLQDQGSKAEDSVLLKKKL
EEHLEKLHEANNELQKKRAIIEDLEPRFNNSSLKIEELQEALRKKEEEMKQMEERYKKYLEKAKSVIRTLDPKQNQGAAPEIQALKNQLQ

--------------------------------------------------------------
>In-frame_ENST00000397171_ENST00000307602_TCGA-HB-A5W3-01A_SCMH1_chr1_41578955_-_HOOK3_chr8_42761316_length(transcript)=15131nt_BP=990nt
TTAATCTTATACTTTCTTTCCACATGACTATTTTTCTCTCCCTCTGCAGTGATAGACTGGAGTGATGTTAGAAAACACAAATATGGTCAC
CTATCAGAGTCTGCATCCCAATATCAAGAAGCTGCTGACATCCTGGATCTAGGGTTGTAAAGAAGATTACATGAGCTAATGGATGTGAAA
ACATCTTAAAAACTCTCAAATACTTTTCAACTTTGGAGGATTATTATGATTTTCATTCTGTTCAGCGGCTATACTCAGACTTTACTCTAA
AAGTCAAATCTTCTGACATTCTTTGAAGTGAAGCATTCTATGAATGTGAGCTGAAGAAATGAATGAAATGAAATAATGCAGGTCATTTTA
CCTGGGACAAATACCTAAAAGAAACATGTTCAGTCCCAGCGCCTGTCCATTGCTTCAAGCAGTCCTACACACCTCCAAGCAACGAGTTCA
AGATCAGTATGAAATTGGAAGCACAGGACCCCAGGAACACCACATCCACCTGTATTGCCACAGTAGTTGGACTGACAGGTGCCCGCCTTC
GCCTGCGCCTTGATGGGAGCGACAACAAAAATGACTTCTGGCGGCTGGTTGACTCAGCTGAAATCCAGCCTATTGGGAACTGTGAAAAGA
ATGGGGGTATGCTACAGCCACCTCTTGGATTTCGGCTGAATGCGTCTTCTTGGCCCATGTTCCTTTTGAAGACGCTAAATGGAGCAGAGA
TGGCTCCCATCAGGATTTTCCACAAGGAGCCACCATCGCCTTCCCACAACTTCTTCAAAATGGGAATGAAGCTAGAAGCTGTGGACAGGA
AGAACCCTCATTTCATTTGCCCAGCCACTATTGGGGAGGTTCGGGGCTCAGAGGTGCTTGTCACTTTTGATGGGTGGCGAGGGGCCTTTG
ACTACTGGTGCCGCTTCGACTCCCGAGACATCTTCCCTGTGGGCTGGTGTTCCTTGACTGGAGACAACCTGCAGCCTCCTGGCACCAAAG
ATCCAGACATTTAATGTGGATGCACCATGCCAGACCGTGGAAGATTTAACGAATGGGGTTGTGATGGCCCAGGTTCTTCAAAAGATAGAT
CCTGCATATTTTGATGAAAATTGGCTAAACAGAATCAAAACTGAAGTAGGAGATAATTGGAGGCTAAAGATAAGCAATTTAAAGAAAATT
TTAAAAGGAATCTTGGATTATAATCATGAGATTTTAGGACAGCAAATTAATGACTTTACCCTTCCTGATGTGAACCTTATTGGGGAGCAT
TCTGATGCAGCAGAGCTTGGAAGGATGCTTCAGCTCATCTTAGGCTGTGCTGTGAACTGTGAACAGAAGCAAGAGTACATCCAAGCCATT
ATGATGATGGAGGAATCTGTTCAACATGTTGTCATGACAGCCATTCAAGAGCTGATGAGTAAAGAATCTCCTGTCTCTGCTGGAAATGAT
GCCTATGTTGACCTTGATCGTCAGCTGAAGAAAACTACAGAGGAACTAAATGAAGCTTTGTCAGCAAAGGAAGAAATTGCTCAAAGATGC
CATGAACTGGATATGCAGGTTGCAGCATTGCAGGAAGAGAAAAGTAGTTTGTTGGCAGAGAATCAGGTATTAATGGAAAGACTCAATCAA
TCTGATTCTATAGAAGACCCTAACAGTCCAGCAGGAAGAAGGCATTTGCAGCTCCAGACTCAATTAGAACAGCTCCAAGAAGAAACATTC
AGACTAGAAGCAGCCAAAGATGATTATCGAATACGTTGTGAAGAGTTAGAAAAGGAGATCTCTGAACTTCGGCAACAGAATGATGAACTG
ACCACTTTGGCAGATGAAGCTCAGTCTCTGAAAGATGAGATCGACGTGCTGAGACATTCTTCTGATAAAGTATCTAAACTAGAAGGTCAA
GTAGAATCTTATAAAAAGAAGCTAGAAGACCTTGGTGATTTAAGGCGGCAGGTTAAACTCTTAGAAGAGAAGAATACCATGTATATGCAG
AATACTGTCAGTCTAGAGGAAGAGTTAAGAAAGGCCAACGCAGCGCGAAGTCAACTTGAAACCTACAAGAGACAGGTAGTAGAACTACAA
AACAGATTATCCGAAGAATCAAAGAAAGCAGATAAACTAGATTTTGAATATAAGCGGCTAAAAGAAAAAGTTGACAGTCTTCAAAAAGAA
AAGGACAGGCTGAGAACAGAAAGGGATTCTCTGAAGGAAACCATTGAAGAGCTTCGTTGTGTACAAGCTCAAGAAGGGCAGCTCACAACA
CAAGGGTTAATGCCTCTTGGAAGTCAGGAGTCTTCAGACAGTCTAGCTGCAGAGATTGTTACACCTGAAATCAGGGAGAAACTTATTCGT
CTTCAGCATGAGAATAAGATGTTAAAGCTTAACCAAGAAGGTTCGGACAATGAAAAAATAGCCTTATTGCAGAGCCTTCTAGATGATGCA
AATCTACGCAAGAATGAACTGGAGACAGAGAATAGGCTGGTGAATCAAAGACTTCTGGAAGTACAGTCACAAGTTGAAGAATTACAAAAA
TCTTTACAGGATCAAGGCTCAAAAGCAGAAGATTCAGTCCTTCTAAAAAAGAAGCTTGAAGAACATCTAGAGAAGCTGCATGAGGCCAAT
AATGAACTACAGAAGAAGAGAGCCATTATTGAAGATCTCGAGCCAAGATTTAACAACAGCTCCTTAAAAATTGAAGAATTACAAGAAGCT
TTACGAAAGAAAGAGGAAGAAATGAAGCAAATGGAAGAACGATACAAAAAATACTTAGAGAAAGCCAAAAGTGTCATCCGTACTTTAGAT
CCTAAACAGAATCAAGGAGCAGCACCAGAAATACAAGCTCTTAAAAATCAGCTCCAGGAACGAGACCGACTGTTCCACTCATTAGAGAAA
GAATATGAGAAAACAAAGAGTCAGAGAGAGATGGAAGAGAAATATATTGTTAGTGCCTGGTACAATATGGGAATGACCCTGCATAAAAAG
GCAGCTGAAGATAGACTGGCAAGCACAGGCTCAGGGCAGTCATTTCTGGCGAGGCAGAGGCAAGCGACCAGCAGCAGAAGATCATACCCA
GGCCACGTGCAGCCGGCCACAGCAAGGTAGAGAAGTTGTGCCGCTCAATCACAGACACCTGCACCCACAACATACTTCTGTTACACACAA
GAACATTTCAGGAAACTCAGCCAGCTTATTTTTTGTTTCTCTTCTATGTCAATACTTAGTGTTTCTCATTTTGAGGACTTTTTCTCTCTC
CTGTATCTTTGTTTTAGTTTCTTTGGTTTTTATTTTGTAGTCCTTTCAGTTATTTTTAATGTGCCAAAAATTTGTACATGTTCAATTAAA
AATGTTGTATAATAGTGTAATACTTTTCTTTGTATGAAAATGTCCTCTTCTTCAAAGGTATAGGCTTTGTAATGAATTAGATTTTCTGCC
AATAATTGATATACAATTTATATTCTTTATTGTGCCTGTGTGTTACCATGCTAAGAATGTCTTTGTTTAAAGGGAATTAATCTTTTTATG
ATGTATTAATCTGTGTTTTCAATTGTTTTCCAAGTACAGTTCAAATAACTTGCATATTTACTATACAAAATGGTTGACAAGTGTTCTTTT
TGCAAAGACTTGAATACATTGGCAGAGGTGCTAATCACATCTTCCCTAAGGCACCTGGAAGAATTATTTGAGGAAAAAATGAGTTTTCAC
ATTGTTTTATAGGAAATTAAATTTGTCCAAAGATTTGGAGACTATTTTTAAAACATAAATACATAAAATTTCATTATTTCCTGCTATCTT
GTTTGCTGGCAGAAGTGAATGTTTGGTGAGGTTATTTTGGGATAAATTACAAAAGAAAAAAAATTAGACACTGCATTAATTTCTTGTTCT
TTTGGAATATCTTAGTAACTGAGGATCATTTTCTAACAATGTGGTTGACATACCTTCAGTTGCTTTCCACATCTAAAAGAGTTATCTTTC
ATATATGTACAAGTTATTGGTAGTCTTATTTTTGGGCTGTTTGTTGACTTATGCCCCATTTGTTTTACTTGTTCTTTAATATAAACCCTT
CCATTTTTTAACAATTCCTAACACTTGATATCTTAATATCAGTCACTAACATTAGTAACTTCTTGTATGTTATATTATGGCAGATCTCTT
TACGTTTTTTCTCACATCTATCTGCTAGTCCAGGAATTTGTTACTAAATAGATTTTCTTGGATATTTGGTTGCCTCAAAGTGCTTACATT
TGTTAACAGATTGTAAACCACATTTATTTACATTGATGAATGGGCTGTTGAATAATCATTGTAAAGCACTTTGTATATATAAGGTGCTAT
ATAAGTGTGAAATATCATTCATTTATAAATGAAATGCCTTCTAACTTTCCATATTGACTTATGTATTTGGTCCCAAATTATATTTAAGTC
TTTTTTCTTGCAACGTAGCCCATTTTTTGAAAGCAAAACATTTCTGAAATTAGGTCATGGTTTTTTTGTTTATTTTTAGGTTAGGTCACT
TAATATAGGAGGATGTTTTCTCATGTACTTGCTATTTGCAAGTTCAGGTTTCATTTGGTTCTTTATGTTAAATACGAATAAGTAACCTCA
AATCAAGCTAAATGTAATTAAGAATTTTCAGCAACTATATTCAAGTGTTTGATTTTTAAATTCTTTCTTTCTTTTTAATAAGAAAGATGA
CCTAAAAATCAGTGGTATTTGTTTGTCCTCAGAAGCCGTAGTTGAAGAAAGATATTAGAGTATACACAGAACTGGAGCCATACATTGTGC
TAATTTTTTACATTAAGTACAGAAGTCTGAGCACAGCATGAATGCTTCTGCCTGACAGGACCACAAAGCAGCAGAAGTTAGGGATAAATG
GAGATAGCCATGAGTAGAACTGCTGTAGGGCTTCAGGAGGCTACGCAGACCTGATCAACTGCAAAGTTTCCAAAGTAAAAGATTAAAAAC
TTTCAGACGGTTCTTACCTCTACCCGTGTTTCACAAATAGCCTGAGGATCCAACTATTTTTAAAGCAAATTGGGGCCAGACGTGGTGCCT
CACGCCTGCAATCTCACCATTTGGGAGACCTAGGTGGGGGTGGATCACTTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGTGAA
ACCCCATCTCTACTAAATTACAAAAATTAGCTGGGCATGGTGGCATGTGGCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAGTC
ACTTGAACTCAGGAGCCAGAGACTGCAGTGAGCTGAGATCGCACCACTGCATTCCAGCCTGGGCGACAGAGTGAGACTCTGTCTCAATCA
GTCAATCAATCAATCAATCAAATTGGAATATGAGCACTAACCTTGGTAAGTTAAAATTTTGGGAAAATTGTACCTGCAGAATATGATGGA
TGAAAACAACAGCCAGGTGCAGTGGCTCACGCGTATAATCCCAGCACTTTGGGAGGCCGAGACAGGCACATCATCTGAGGTCAGGACTTC
CAGACCAGCCTGTCCAACATGGTGAAACTCCGTCTCTACTAAAAATACAAACAATTAGCCAGGCATGGTGGTGTGTGCCTGTAGTCCCAG
CTACTTGGGAGGGTGAGGCAGGAGAATTGCTTGAACCTGGGAGACAGAGATTGCAGTGAGCCGAGATGGCGCCATTGCACCCCAGCCTGG
CGACAAGAGCGAAACTCTGTCGCAAGAAAAAAAAAAAAAAAAAAAAAAAAAAAAACAGTCTGTGAACTACTCACTGAATGAATTTTGTTC
TGTGAGATGAGAGGTTTTCATTTTCATTTTCTATTTACAGCCCCAGTCCTAATCTCCTACCCATCCACCTACCCAGATATTTTTTCTCTA
TCTGGGTTGGAAAGGCCCCAGGCTTTTAGAGGGGAGTTTTACTTCTGACTTTTTTTTCCCCCCGAGACGGAGCCTCGTTCCGTCACCCAG
GCTGTAGTGCCGTGGCATGATCTCGGCTCACTGCAGCCTCTGCCTCCCGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCAGAGTAGCTGG
GATTACAGGTGCCCACCACCATGGCTGGCTAATTTTTGTAATTTAGTAGAGATGGTGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTC
CTGACCTCGTGATCTACCCACCTCGGCCTCCCAAAGTGCTGAGATTACAGGCACGAGCCACCGCGCCCAGTCGTACTTCTGACTTTTCTT
CAGCATCTGTTGTATGCTATTATTTTGATGTTTACATTTATAATTTTCTTTCTTTTTTTTTTTTTTGTGAGATGATGTCTCGCTCTGTCA
CCCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCTGAGTA
GCGGGGACTACAGGCGCCCGCCACTACGCCCGACTAATTTTTTGTATTTTTTAGTAGAGACGGGGTTTCACCATGTTAGCCAGGATGGTC
TCGATCTCCTGACCTCGTGATCCACCCGCCTCAGCCTCCCAGAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCAGCCTACATTTATA
ATTTTCATTCTCTTTTACCTATAAAATTCAGTGTATTAGTTTCATTACATAGGAGAAATTATATTTCTAAACATTTTATGATGTTTAAAA
ACAAAACAGGCTGTTGTAAAAAAAAAAAAAAAAAAAACTTCTGAATATACTTTAGGTATCAGAAAGCCAAGAATAAAATTTAGCTCTAAC
GGTGGCAACTCCATGTCCGGTGTCCAGCTTTGGACAGGGTTTATGACGTTTCTGTTTCTCTAGTAATGATTAATGATTCCTCAGGAGATT
CGTGATGTTGTCTGGTCTATCTGGAAATTTAAAGTCACTAGGAGCTTTGCCTCATCGTGAGTGATGCTGTGCTGTATTTTTACAAACTCT
CGCATACAGCACCTTCCTGGGGCCACGTTGGCTTGTGCAGTGGAGCTTGTCCAGGCACCAGCATGGAGCAAGTACAGGGTTGCTGTGTTG
GGTTGGAGCACACTGTCACCACAGTGTCTGAAGTCTTATAAACAGGAAGATCATTTTCTGTTTTCCTTCTAACCAGGGTGAGAAAATACA
AAGTAAAGAACTAAAGAATATTAAAACCTAGCATTTATGTTCCACAGTGTGTATTTCAGAAGTTTGTAATCCAGAAAATATAGTAGTGTA
TAATATCTGAAAAGAGAATCAAGTATACAATTGTACATATTTTTAAAGAACTTTGAAAAACTCCGTCATATCTTTTACCATTTGTCTATT
TGATAGTAATGCAGAAAAAAGTCCCTAAAGACCCTGTGTTCCAAAATTTACCAAGATTGACATTTCTATTAGACATCCTTAACCTAAGTG
TTTTAATTAGATTATTAGACTATAATAAGGATGAAATTGCTGTCTGTAATTTTGTTGAGGTTTTATTGTTAATATAATAAAAGCTCAACT
GTACAAAATTAAGCTAAATGTTATCCAGTCAGAAACATCAGCCTGTGGCCAGGTGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGA
GGCCAAGGCAGGCGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCTAATATGGTGAAACCCCATCTCTACTAAAAATACAGTATT
AGCCAGGCATGGTGGCAGGCGCCTGTGATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCATGTGAACCCAGGAGGTGGAGGTTGCAG
TAAGCCGAGATTGTGCCACTGCACTCCAGCCTGGGCCACAGAGTGAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAAAAGAAACATCAG
CCTGTATATTCCAGTAGTTCTCACAGAAGAATGAAAATCCGTGCTGTGCAAATAGATCAGTAGTGAGTGAGTGTTAAGTGAAAGATGAGC
TAGGTTGAAGAAAATATACATTTTATTGATGAGCCACTTTGCTATCTCTCCTTCCTTCCTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCC
TTCCCTTCTTTTCTTTTTTCTTTTCTTTTCTTTTCTCCCTCCTTTCTTCCTTCCCTTCCCTTCCCCTCCCCTCCCCCAGGCTGGAGTGCA
GAGGCACGATCCTGGCTGACTGCAAACTCTGCCTACCAGGTTCAAGCGATTCTCCTGCCTCATCCTCCCTAGTAGCTAGGATTACAGGCA
TCTGCCACCACGCCCAGCTAATTTTTGTATTTTTACAAAATACAAAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCTAACTCCT
GACCTCAGGTGATCCGTCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGTGTTACTGCCCCAGCCTCCTATTTCCTTTTCGAAA
GTAGCAGTTTGGTTTATTCTCGTTTGCTAAGTAATTGTTTGAAATATTTTTCAGCCTCTCCTGCTCCCTCACAAAAATTCACCTGTCATT
TTAATGATAACAGCATGTTAAAAACTTGGAAGTCTTTATCCCAATATAAGAATTATCTTGAAACAAAAATCTAAATTACTTTTAAAAATT
CTCTTAACTCTGCATTTAGTCTCCTATTATCTAGATCTCTGAGTCCAGGATAACTCCAGTTATCCCCAGTTGGATCATGTGTGATTTATC
TGAGAAAGCATCCACAACCCACAGCTAGTGGAAACCGAGCTAGTTTACAGCCACGTGGATAAGAACATCTTTGTTTCTAAAGTGAGAGGA
AAGTGCTTGGTATCTTGCTTTTTGCTGAGGGCAAAATAACAACATGAAGACAAAGTGCTTTTTGTTGTCTATTCATGAAACTGTAGAAGA
ATATTTTGAGTTTTTATTCTTATATTATGAAGGGATTCTTTGCCTAGCAGTGGCCGTCAAACTGATGTAGCATTGTACTTCTCAACAGTG
AAGCCTGTGTAATACCATACAGTAGGATGAAAGACTATTCTGAGCAAAATCAAATGGGATGTCAGAATCTTTGAAAATTATTTTATCATT
TTTTCTATTTTTTCATTTTTATAAATTAGAAGGATTTTCCATTCAATAAGGATAATCTCTCTTCCTATCATTCTGTCAAAATGGCAGTTT
CTTTTGGTAATTATCCAACCTAGTTTCATTACATTTAGAAGGAGGTTTCAGAGCTTATTCTTGATAACTATAATAATGATTTGAATGTTT
TATATCATGAAGTTTTTTCTATGAGGAAGGCTATTCTCAATGTATCTGTCGTCTAATTTTTTATTTTCTATCTATAAAGAATATTTAAAT
AATAATTGGTGTATGTTCCTTTTGTTGAAAATGTTTTATTGTCCAGTTTTAACACAGAAGTGGTCTAAAGTTTTGCAGCAAATGCTGTTC
AGTTCCCAGAAGCCTAAAAAACATAACATAATATGCTAACAGAGCTAATTTCCACCCAATCCCTCAAATTACCGAAGTATTAATATTTAG
CTTCCTTTCTAGAAAACAAGGGGCAGCACAAATGGGGTGGCATCCATCTCTTTTAAATCACTGATGATTTTCTGGGGAAGTATATATAGA
TGATTTTATTTTTTAAATAGCCTTTTATCAAACCATTTCACATGTATTATCTATATGACTATAGAAACTTATAAAACATTTAATTCATGT
TGACTTAAAACATGGGCATCCTTGGATTCTCCACATTGACTGAAATGATAGAGAAAGGGACATTTGTTTGAGAAACAAGAGACCTGTACC
TAATTATGGCAAGTATATGAGTTTTGGTGATTGTGGGGGGTTATAAATGTTTTCCTATGATAGATAAATATATAGATATAGATCAGGAAT
TACTTGATGTCTCTTCAGAAGTTTTCTGTTTTCTTATAATTTCCAGTAATACTCTGTAAGACTCGGTTTGCATGCTGTGTGTGTTTGCAT
GAGTATAGAAACCTAAGAACATAATGGAAGGCTATTAAGGCAAATTCATTCCTAGAAAGTGGAGTGGATCATTGGGATAAGAAATAGCCT
AATTATAAACAAATATGCAGGCAGAGGGAAGTCCTAATACAATGAAAACTTGCATTATCTAAACAGATGTTCCCAAAGCAATAGTTTGCC
TAAAATCCTCTGTATTACATGATTATTCAGTAAAAGAGTAAACAAATATCTAATTTATTTTCTAATTGTCCTTCCCTTCATTGAGTATTA
ACTAGGTGCATAATGTAGTTGTATATGTTTACTAGTAAAGGGAAAAACACTTATTTTCATTTTGAGACTGTTTGGCTATTACTAAAGCTG
AGAAAGTGATTTTAGGTCGCCAAGGATACTATGATTTGATGAGATGAGAAGAAATCTGCGGTGGCTGAAAATCGTGACCAACTTGGTGTT
ATCTAGATCTGCTTTATCTAGTTTGCAAGCCATAGGCTCAATTTTATGTCCTTCTTACTTACACACAGTAGCCCCACACAGTTTTGTTTT
AAATGAAGGCAAAAGTAGACATTTTTAAAGTATATTCAACATTGTGCCATTATTTACCTGATAAAGGTGAAATCAGAGGTGTCCACGGCC
TCAAAGTTTGGGCCCATGGGACTATCAAATCCGAATTATATCTACTTAGAGCTTAGAGGAAGAATTAGGTATCATGAGAAAAGCAACTCC
TACTTGAGAGAAAGAAGACTACCAAAGCATGTTGAGGCTTTAACATGGGAGACTTCCAGGTAGGCGTTAACACTTGAGTGGTAACTAGCT
TGATGAAGGAAAATAATTACTTTAGCAGTTATGTTGTAAAATTAATAAAAAGGACTCATGTTTATTCTGGTGTATTTGTCAACCCATGGG
TAGTGATTACTCCGTGTACATTCTATAGTGTGTGTATTTTATTTAGTGTCTTAATATATAGTCTTTATATAGTATCTTAATATTATTTAC
TGTTACTTCTAGTCATTTATGTAGTATATTTTACTGCAAAATTTGTAGCACTTTACTAATATTAGATCATTATTTTCCCTCTTCCCCTCT
ACCTTTCTGGCATTTTCTGTTATCTTAGAGTCAGGAATCTAAAGGTCTAAGTCTAGAAATCTGTTGGAAGCTGGGTTGGAGCTACTGGAT
ATGAGTTACTTTTTACATGTCTCCTTAAGAAGACTCTTTTATAATGTAATACTTAGAAGCCAAATCCTTTCAAACGCAAACACCCTTGAA
ACTTGATGCTTTCTGAAGTTGTATTCATAAAAATTATCCCATCTTACAGTTAATCAGAAGATGTTCTTACCTTTGGTTTGCCTGCCTCCT
GAAACACAAACCTGCAGATTGCCCCTAACTTCAGCAGTGCCTCCGTCACTGCATGTACCTAAAAGACAGGAAAGCCAAGTTCTGGGAGCT
GTCAAGTCGGAGGATCAGGAAAATGGTGGGGAAGAGGTGACTGGAAAGGCAGGCACTAAAGATGGCAGGCTGCAAAAGCATTCTGAGTTC
CCCTGTAACAGATAGGTTTTATGAACTCAGCTGTTTTCTTTTTTCTTTTTTTTTCTTTTGAGATGGAGTCTCACTCTGAGTCTCACTCTG
TTGCCCAGGCTGGAGTGCAGTGGCACAATCTCAGCTCACTGCAGCCTCCACCTCCCGGTTTCAAGTGATTCTCCCACCTCAGCCTCCCGA
GTAGTTAGGATTACAGGTGCCCACCACCACGCCCAACTAATTTTTGTATTTTTAGTAAAGACAGGGTGTCGCCATATTGGCTAGGCTGGT
TTTGAACTCCTGACCTCAGGTAATCCACCCGCCTCAGCCTCCCAAAGTGCTGGGATTATTATAGGCGTGAGCCACCATGCCCAGTGAACT
TGGCCATTTTCTTACATTCATATATAGCAAAGTTTTCAACTTGTCTACCGAGAGACTTTCTTTAGGAGCCAGGACTTCTACATTTGTAAC
TTGAGTATATTAATATTCAAATCATAGTTCAAAAATACTGAAATACTTGTTTATTATGTTACATAAATATGGACACAATTACTGCCAAAG
AATAGAGAGATTTGCTTATGAGAACATTCTGTCATTTGTTCTGTTTGTAGATGAGAGACATGCTTTTAAAGTACAAAACGTTTCTCTTCT
ACCTTACCCCCTGTTCTACTGACGTGCTTTGCATGAGAAGCTCATCTAGAAGAGAGCAACGCTGGAATAGAGAAGTCTAGACCCTGGCCT
TTGAGGGAAAGGACTGCTTTTTTTCTCTCCCAAATTAGAAAATTAAAAGTGAAACATAACACATAAGGACGAAATACAATGTTCTGAATA
TCTTCCACTAATTAATTGTTGAATGATTAAGTCTCTAAGTATCTTAACTTCCATTGTCTTCTTGTTAACCTAGACAAGAGTAGATTATTC
AGTAGCCACATGTGACAGTTAAAATTAAGTAAAATTAAAACTATAGTTTCTCAGTGGCCTAGCCACATTTCAAGTGTTCCACAGTCACAT
GTGGATAGTAGTTACCTATCAGACAGTACAGGTATAGAACATTTCCAGTATTGCCAAAAATGCTATTCAACAGCACTTTTATTGCCCAGA
GAGAAAATAAGGACAAAATAAAGGCAGTGAAGTAACTTAAGACAACTCTGAGATTTTACCACCATACTTAGAGAAAGTTTTTCTGTTATA
AAAATTAATACTAATCCTTTTTAAAGACCTTGGAAAAAATCAAAACCCCATTCCTTTAAGCTAGTCTTCAGTATATATTTTTCTAAGAAC
AGATTCTCAATACTTTATTTTTCAAGTGATAAAATCATTTTATAAATCATTTCTTAATATCTTCAGTGTTTTTTCCCTTTTTATGTAAAC
TCTTTTAAAATTGATATTAGCTGGGCATGGTAGCTCATGCCTGTAGTCCCAGCTACTCCAGAGGTCGAGGCAGGAGCATCGCTTAAGCCC
AGGAGGTTCAGGCTGCAGTAAGGTCTGATCACACCTGACTGCACTCCAGCCTGGGTGGCAAAGCAAGACCCCTGTCTCTAAAAAAAAATA
ATATAAATTGATGTTATATAGTTAACATTTATCAGGCAAATTCATATGAATGCTTATTTCAAATAAAGATTGATAGATTTAATGATATCC
TTCCTTTTAAATTTATATAGATCTAATGAACATTGCCAACAGTTTTTTTTGTTTCTGTCCCTTAAACATTTCCCCTGAAAGTCCACCTCA
AAGGTACATCAAGATGCAAACAATTTTTTTATCTTCATAACTTCCTGCTCTTATTAACTTGTATTATGAATCAAATTAAGTTTTATGTAT
AAGGCATTTACTATTCCAGTGACTTAGCTAATGAAAACATTTAAAAATATGTATTAATTTACTTGGCCTGCTACTAAAGTGCTTAACATA
ACTAAATGGATCTATAGTAACATGTCTAAATTTTTTAATGGAAATAAGGGACTAACCATAATCCTTTTGAGTCAGCTTGGTGCTTACAAT
TATTTTGTTAGGAAATCTTGATGCTTTCTTCTTTCTCTTTAAATTTTTGTAATCAAGCAACAGACTTGATCCAGCAGTGTCGAATTCCAA
GCAAGTTATGATGATTCTTATTGTAGTTCAAGTACAGATGAGTAAGTGGTGTGACTTCAGTTTATTATCTTCTTGGTGACCTACTTTAGT
ATGTGTTCTGTAGCGATTCATATTAGTTAAGGGACGTTTTCAATATGCTTGAAATAAGAAATAGCATTTTACTCTAAATACAAGAAATGA
CTGTACACAAATGCTAATCAGTGATTTGGGGCCTTTTAATGTCTTTAACAGCAATCTTTTATTTATTTATTTATTTATTTTTGAGACGGA
GTCTTGCTGTGTCACCAGGCTGGAGCAGTGGCACGATCTCGCCTCACTGCAACCTCCGCCTCCCAGGTTCAAGCTATTCTCCTGCCTCAG
CCTCCCAAGTAACTGGGACTGCAGGCACATGCCACCACATCCAGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCTTGTTGGCC
AGGATGATCTCGATCTCTTGATCTCGTGATCTGCCCGCATTGGCCTCCTGAAGTGCTGGGATTACAGGCATGAGCCACTGCGCCCGGCCC
AAATCTTTTATTTTTTAACAGCCTTAGTTATTTATAATTCAAATGCACTAAAATATCATCGCTGTCATGAACTTTGCTGTTTACAGGTTC
TGTGTAATTCAGAATGCTTTGTACTTAGAAAATAATTTCTAGGCTTATCTTGTTTTGCAGTTTTCATGTTTTGACAATTGCCCACCATTT
ACAATACTCAATTTTTGATTATGAAATGAATAGTAAAATTCAAACATATCTAATAATAATTTGCCTTAGTTTGATTAATAAATTATATCA
AAAAACTTGGGGATAGAAAGAGGCTTTTTTTTCCCCCTGTAGTATTTTTAAAACTTTTTAGATGAGCTGGATGAAACCTTAGTACATTGG
AGCTGGAGTTGTATTGAGTACAGCCCCAACTCTGAAGCCTTATATTCATGTCTTAAGTACCATTGATTGTTCTGTGAATTGTTGTTAGTT
TCATATTTGACATTGTAGTAATCCACCTTGCATTTTAGTCTTTGCAAAAAGGATATTGCTAGGTATATTCTTATTTCTGATTGAGTATTG
AATTTACATTTTTCAGAATTTCATTCTTTGTCATTATAATCCAAAAACAATGTCCACATCAGACTTGGAACTTCTCACTTCAAAAATGAA
ATACAGATTTAGCAGTGTTGTACATAATGATGTCCAAGCATTTTTCCACCTGTTTACTGAGTTTTCCAACCATTTACTATGTGTTGAGAT
TGGTGGGTTTTCTGGCTGTTTTTCTGAGGTGAATGACTTGTTACAGAGCCTCAGTAAGAAATTTCAACTAAAATCACAAAAACATAAAGT
CCAGGAAACCACCAGAAGATGGATTTTTAGTGTTTTTGAAATCTTGTATTTCCTTTTGATATCATTTACTCATTTTAATTTTACGACTGC
CAACTTGTTACGGTATTAATTATATGTATGTGTTTATATGTATGCATATAATATATGTATATGTATATGAAGAATAAAGTTAAGATTTGG
TCAAACTATATTTTCCCATTCAAGTACAAAAATGTTTTCAAGGCTGCAAAAAGTGTACAGTTGTTAAACAAGTTGTAAATAAAGACTTGT

>In-frame_ENST00000397171_ENST00000307602_TCGA-HB-A5W3-01A_SCMH1_chr1_41578955_-_HOOK3_chr8_42761316_length(amino acids)=710AA_start in transcript=957_stop in transcript=3089
METTCSLLAPKIQTFNVDAPCQTVEDLTNGVVMAQVLQKIDPAYFDENWLNRIKTEVGDNWRLKISNLKKILKGILDYNHEILGQQINDF
TLPDVNLIGEHSDAAELGRMLQLILGCAVNCEQKQEYIQAIMMMEESVQHVVMTAIQELMSKESPVSAGNDAYVDLDRQLKKTTEELNEA
LSAKEEIAQRCHELDMQVAALQEEKSSLLAENQVLMERLNQSDSIEDPNSPAGRRHLQLQTQLEQLQEETFRLEAAKDDYRIRCEELEKE
ISELRQQNDELTTLADEAQSLKDEIDVLRHSSDKVSKLEGQVESYKKKLEDLGDLRRQVKLLEEKNTMYMQNTVSLEEELRKANAARSQL
ETYKRQVVELQNRLSEESKKADKLDFEYKRLKEKVDSLQKEKDRLRTERDSLKETIEELRCVQAQEGQLTTQGLMPLGSQESSDSLAAEI
VTPEIREKLIRLQHENKMLKLNQEGSDNEKIALLQSLLDDANLRKNELETENRLVNQRLLEVQSQVEELQKSLQDQGSKAEDSVLLKKKL
EEHLEKLHEANNELQKKRAIIEDLEPRFNNSSLKIEELQEALRKKEEEMKQMEERYKKYLEKAKSVIRTLDPKQNQGAAPEIQALKNQLQ

--------------------------------------------------------------
>In-frame_ENST00000326197_ENST00000307602_TCGA-HB-A5W3-01A_SCMH1_chr1_41578955_-_HOOK3_chr8_42761316_length(transcript)=15156nt_BP=1015nt
AAGCTGCTGACATCCTGGATCTAGGGTTGTAAAGAAGATTACATGAGCTAATGGATGTGAAAACATCTTAAAAACTCTCAAATACTTTTC
AACTTTGGAGGATTATTATGATTTTCATTCTGTTCAGCGGCTATACTCAGACTTTACTCTAAAAGTCAAATCTTCTGACATTCTTTGAAG
TGAAGCATTCTATGAATGTGAGCTGAAGAAATGAATGAAATGAAATAATGCAGCATCTAGTGCTTTTTGCATGGCCCAAAGGGGCTCTGT
GCTGCTCCACTACAGAGGAAACTTCAAGAAATGCTGGTTTGCTACAGTGTTTTAGCTTGTGAGATTCTCTGGGACCTTCCCTGCTCCATC
ATGGGGTCACCTCTAGGTCATTTTACCTGGGACAAATACCTAAAAGAAACATGTTCAGTCCCAGCGCCTGTCCATTGCTTCAAGCAGTCC
TACACACCTCCAAGCAACGAGTTCAAGATCAGTATGAAATTGGAAGCACAGGACCCCAGGAACACCACATCCACCTGTATTGCCACAGTA
GTTGGACTGACAGGTGCCCGCCTTCGCCTGCGCCTTGATGGGAGCGACAACAAAAATGACTTCTGGCGGCTGGTTGACTCAGCTGAAATC
CAGCCTATTGGGAACTGTGAAAAGAATGGGGGTATGCTACAGCCACCTCTTGGATTTCGGCTGAATGCGTCTTCTTGGCCCATGTTCCTT
TTGAAGACGCTAAATGGAGCAGAGATGGCTCCCATCAGGATTTTCCACAAGGAGCCACCATCGCCTTCCCACAACTTCTTCAAAATGGGA
ATGAAGCTAGAAGCTGTGGACAGGAAGAACCCTCATTTCATTTGCCCAGCCACTATTGGGGAGGTTCGGGGCTCAGAGGTGCTTGTCACT
TTTGATGGGTGGCGAGGGGCCTTTGACTACTGGTGCCGCTTCGACTCCCGAGACATCTTCCCTGTGGGCTGGTGTTCCTTGACTGGAGAC
AACCTGCAGCCTCCTGGCACCAAAGATCCAGACATTTAATGTGGATGCACCATGCCAGACCGTGGAAGATTTAACGAATGGGGTTGTGAT
GGCCCAGGTTCTTCAAAAGATAGATCCTGCATATTTTGATGAAAATTGGCTAAACAGAATCAAAACTGAAGTAGGAGATAATTGGAGGCT
AAAGATAAGCAATTTAAAGAAAATTTTAAAAGGAATCTTGGATTATAATCATGAGATTTTAGGACAGCAAATTAATGACTTTACCCTTCC
TGATGTGAACCTTATTGGGGAGCATTCTGATGCAGCAGAGCTTGGAAGGATGCTTCAGCTCATCTTAGGCTGTGCTGTGAACTGTGAACA
GAAGCAAGAGTACATCCAAGCCATTATGATGATGGAGGAATCTGTTCAACATGTTGTCATGACAGCCATTCAAGAGCTGATGAGTAAAGA
ATCTCCTGTCTCTGCTGGAAATGATGCCTATGTTGACCTTGATCGTCAGCTGAAGAAAACTACAGAGGAACTAAATGAAGCTTTGTCAGC
AAAGGAAGAAATTGCTCAAAGATGCCATGAACTGGATATGCAGGTTGCAGCATTGCAGGAAGAGAAAAGTAGTTTGTTGGCAGAGAATCA
GGTATTAATGGAAAGACTCAATCAATCTGATTCTATAGAAGACCCTAACAGTCCAGCAGGAAGAAGGCATTTGCAGCTCCAGACTCAATT
AGAACAGCTCCAAGAAGAAACATTCAGACTAGAAGCAGCCAAAGATGATTATCGAATACGTTGTGAAGAGTTAGAAAAGGAGATCTCTGA
ACTTCGGCAACAGAATGATGAACTGACCACTTTGGCAGATGAAGCTCAGTCTCTGAAAGATGAGATCGACGTGCTGAGACATTCTTCTGA
TAAAGTATCTAAACTAGAAGGTCAAGTAGAATCTTATAAAAAGAAGCTAGAAGACCTTGGTGATTTAAGGCGGCAGGTTAAACTCTTAGA
AGAGAAGAATACCATGTATATGCAGAATACTGTCAGTCTAGAGGAAGAGTTAAGAAAGGCCAACGCAGCGCGAAGTCAACTTGAAACCTA
CAAGAGACAGGTAGTAGAACTACAAAACAGATTATCCGAAGAATCAAAGAAAGCAGATAAACTAGATTTTGAATATAAGCGGCTAAAAGA
AAAAGTTGACAGTCTTCAAAAAGAAAAGGACAGGCTGAGAACAGAAAGGGATTCTCTGAAGGAAACCATTGAAGAGCTTCGTTGTGTACA
AGCTCAAGAAGGGCAGCTCACAACACAAGGGTTAATGCCTCTTGGAAGTCAGGAGTCTTCAGACAGTCTAGCTGCAGAGATTGTTACACC
TGAAATCAGGGAGAAACTTATTCGTCTTCAGCATGAGAATAAGATGTTAAAGCTTAACCAAGAAGGTTCGGACAATGAAAAAATAGCCTT
ATTGCAGAGCCTTCTAGATGATGCAAATCTACGCAAGAATGAACTGGAGACAGAGAATAGGCTGGTGAATCAAAGACTTCTGGAAGTACA
GTCACAAGTTGAAGAATTACAAAAATCTTTACAGGATCAAGGCTCAAAAGCAGAAGATTCAGTCCTTCTAAAAAAGAAGCTTGAAGAACA
TCTAGAGAAGCTGCATGAGGCCAATAATGAACTACAGAAGAAGAGAGCCATTATTGAAGATCTCGAGCCAAGATTTAACAACAGCTCCTT
AAAAATTGAAGAATTACAAGAAGCTTTACGAAAGAAAGAGGAAGAAATGAAGCAAATGGAAGAACGATACAAAAAATACTTAGAGAAAGC
CAAAAGTGTCATCCGTACTTTAGATCCTAAACAGAATCAAGGAGCAGCACCAGAAATACAAGCTCTTAAAAATCAGCTCCAGGAACGAGA
CCGACTGTTCCACTCATTAGAGAAAGAATATGAGAAAACAAAGAGTCAGAGAGAGATGGAAGAGAAATATATTGTTAGTGCCTGGTACAA
TATGGGAATGACCCTGCATAAAAAGGCAGCTGAAGATAGACTGGCAAGCACAGGCTCAGGGCAGTCATTTCTGGCGAGGCAGAGGCAAGC
GACCAGCAGCAGAAGATCATACCCAGGCCACGTGCAGCCGGCCACAGCAAGGTAGAGAAGTTGTGCCGCTCAATCACAGACACCTGCACC
CACAACATACTTCTGTTACACACAAGAACATTTCAGGAAACTCAGCCAGCTTATTTTTTGTTTCTCTTCTATGTCAATACTTAGTGTTTC
TCATTTTGAGGACTTTTTCTCTCTCCTGTATCTTTGTTTTAGTTTCTTTGGTTTTTATTTTGTAGTCCTTTCAGTTATTTTTAATGTGCC
AAAAATTTGTACATGTTCAATTAAAAATGTTGTATAATAGTGTAATACTTTTCTTTGTATGAAAATGTCCTCTTCTTCAAAGGTATAGGC
TTTGTAATGAATTAGATTTTCTGCCAATAATTGATATACAATTTATATTCTTTATTGTGCCTGTGTGTTACCATGCTAAGAATGTCTTTG
TTTAAAGGGAATTAATCTTTTTATGATGTATTAATCTGTGTTTTCAATTGTTTTCCAAGTACAGTTCAAATAACTTGCATATTTACTATA
CAAAATGGTTGACAAGTGTTCTTTTTGCAAAGACTTGAATACATTGGCAGAGGTGCTAATCACATCTTCCCTAAGGCACCTGGAAGAATT
ATTTGAGGAAAAAATGAGTTTTCACATTGTTTTATAGGAAATTAAATTTGTCCAAAGATTTGGAGACTATTTTTAAAACATAAATACATA
AAATTTCATTATTTCCTGCTATCTTGTTTGCTGGCAGAAGTGAATGTTTGGTGAGGTTATTTTGGGATAAATTACAAAAGAAAAAAAATT
AGACACTGCATTAATTTCTTGTTCTTTTGGAATATCTTAGTAACTGAGGATCATTTTCTAACAATGTGGTTGACATACCTTCAGTTGCTT
TCCACATCTAAAAGAGTTATCTTTCATATATGTACAAGTTATTGGTAGTCTTATTTTTGGGCTGTTTGTTGACTTATGCCCCATTTGTTT
TACTTGTTCTTTAATATAAACCCTTCCATTTTTTAACAATTCCTAACACTTGATATCTTAATATCAGTCACTAACATTAGTAACTTCTTG
TATGTTATATTATGGCAGATCTCTTTACGTTTTTTCTCACATCTATCTGCTAGTCCAGGAATTTGTTACTAAATAGATTTTCTTGGATAT
TTGGTTGCCTCAAAGTGCTTACATTTGTTAACAGATTGTAAACCACATTTATTTACATTGATGAATGGGCTGTTGAATAATCATTGTAAA
GCACTTTGTATATATAAGGTGCTATATAAGTGTGAAATATCATTCATTTATAAATGAAATGCCTTCTAACTTTCCATATTGACTTATGTA
TTTGGTCCCAAATTATATTTAAGTCTTTTTTCTTGCAACGTAGCCCATTTTTTGAAAGCAAAACATTTCTGAAATTAGGTCATGGTTTTT
TTGTTTATTTTTAGGTTAGGTCACTTAATATAGGAGGATGTTTTCTCATGTACTTGCTATTTGCAAGTTCAGGTTTCATTTGGTTCTTTA
TGTTAAATACGAATAAGTAACCTCAAATCAAGCTAAATGTAATTAAGAATTTTCAGCAACTATATTCAAGTGTTTGATTTTTAAATTCTT
TCTTTCTTTTTAATAAGAAAGATGACCTAAAAATCAGTGGTATTTGTTTGTCCTCAGAAGCCGTAGTTGAAGAAAGATATTAGAGTATAC
ACAGAACTGGAGCCATACATTGTGCTAATTTTTTACATTAAGTACAGAAGTCTGAGCACAGCATGAATGCTTCTGCCTGACAGGACCACA
AAGCAGCAGAAGTTAGGGATAAATGGAGATAGCCATGAGTAGAACTGCTGTAGGGCTTCAGGAGGCTACGCAGACCTGATCAACTGCAAA
GTTTCCAAAGTAAAAGATTAAAAACTTTCAGACGGTTCTTACCTCTACCCGTGTTTCACAAATAGCCTGAGGATCCAACTATTTTTAAAG
CAAATTGGGGCCAGACGTGGTGCCTCACGCCTGCAATCTCACCATTTGGGAGACCTAGGTGGGGGTGGATCACTTGAGGTCAGGAGTTTG
AGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAATTACAAAAATTAGCTGGGCATGGTGGCATGTGGCTGTAATCCCAGCTA
CTTGGGAGGCTGAGGCAGGAGAGTCACTTGAACTCAGGAGCCAGAGACTGCAGTGAGCTGAGATCGCACCACTGCATTCCAGCCTGGGCG
ACAGAGTGAGACTCTGTCTCAATCAGTCAATCAATCAATCAATCAAATTGGAATATGAGCACTAACCTTGGTAAGTTAAAATTTTGGGAA
AATTGTACCTGCAGAATATGATGGATGAAAACAACAGCCAGGTGCAGTGGCTCACGCGTATAATCCCAGCACTTTGGGAGGCCGAGACAG
GCACATCATCTGAGGTCAGGACTTCCAGACCAGCCTGTCCAACATGGTGAAACTCCGTCTCTACTAAAAATACAAACAATTAGCCAGGCA
TGGTGGTGTGTGCCTGTAGTCCCAGCTACTTGGGAGGGTGAGGCAGGAGAATTGCTTGAACCTGGGAGACAGAGATTGCAGTGAGCCGAG
ATGGCGCCATTGCACCCCAGCCTGGCGACAAGAGCGAAACTCTGTCGCAAGAAAAAAAAAAAAAAAAAAAAAAAAAAAAACAGTCTGTGA
ACTACTCACTGAATGAATTTTGTTCTGTGAGATGAGAGGTTTTCATTTTCATTTTCTATTTACAGCCCCAGTCCTAATCTCCTACCCATC
CACCTACCCAGATATTTTTTCTCTATCTGGGTTGGAAAGGCCCCAGGCTTTTAGAGGGGAGTTTTACTTCTGACTTTTTTTTCCCCCCGA
GACGGAGCCTCGTTCCGTCACCCAGGCTGTAGTGCCGTGGCATGATCTCGGCTCACTGCAGCCTCTGCCTCCCGGGTTCAAGCAATTCTC
CTGCCTCAGCCTCCAGAGTAGCTGGGATTACAGGTGCCCACCACCATGGCTGGCTAATTTTTGTAATTTAGTAGAGATGGTGTTTCACCA
TGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCGTGATCTACCCACCTCGGCCTCCCAAAGTGCTGAGATTACAGGCACGAGCCACCGCG
CCCAGTCGTACTTCTGACTTTTCTTCAGCATCTGTTGTATGCTATTATTTTGATGTTTACATTTATAATTTTCTTTCTTTTTTTTTTTTT
TGTGAGATGATGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCA
TTCTCCTGCCTCAGCCTCCTGAGTAGCGGGGACTACAGGCGCCCGCCACTACGCCCGACTAATTTTTTGTATTTTTTAGTAGAGACGGGG
TTTCACCATGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCACCCGCCTCAGCCTCCCAGAGTGCTGGGATTACAGGCGTGAG
CCACCGCGCCCAGCCTACATTTATAATTTTCATTCTCTTTTACCTATAAAATTCAGTGTATTAGTTTCATTACATAGGAGAAATTATATT
TCTAAACATTTTATGATGTTTAAAAACAAAACAGGCTGTTGTAAAAAAAAAAAAAAAAAAAACTTCTGAATATACTTTAGGTATCAGAAA
GCCAAGAATAAAATTTAGCTCTAACGGTGGCAACTCCATGTCCGGTGTCCAGCTTTGGACAGGGTTTATGACGTTTCTGTTTCTCTAGTA
ATGATTAATGATTCCTCAGGAGATTCGTGATGTTGTCTGGTCTATCTGGAAATTTAAAGTCACTAGGAGCTTTGCCTCATCGTGAGTGAT
GCTGTGCTGTATTTTTACAAACTCTCGCATACAGCACCTTCCTGGGGCCACGTTGGCTTGTGCAGTGGAGCTTGTCCAGGCACCAGCATG
GAGCAAGTACAGGGTTGCTGTGTTGGGTTGGAGCACACTGTCACCACAGTGTCTGAAGTCTTATAAACAGGAAGATCATTTTCTGTTTTC
CTTCTAACCAGGGTGAGAAAATACAAAGTAAAGAACTAAAGAATATTAAAACCTAGCATTTATGTTCCACAGTGTGTATTTCAGAAGTTT
GTAATCCAGAAAATATAGTAGTGTATAATATCTGAAAAGAGAATCAAGTATACAATTGTACATATTTTTAAAGAACTTTGAAAAACTCCG
TCATATCTTTTACCATTTGTCTATTTGATAGTAATGCAGAAAAAAGTCCCTAAAGACCCTGTGTTCCAAAATTTACCAAGATTGACATTT
CTATTAGACATCCTTAACCTAAGTGTTTTAATTAGATTATTAGACTATAATAAGGATGAAATTGCTGTCTGTAATTTTGTTGAGGTTTTA
TTGTTAATATAATAAAAGCTCAACTGTACAAAATTAAGCTAAATGTTATCCAGTCAGAAACATCAGCCTGTGGCCAGGTGCGGTGGCTCA
CGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGCGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCTAATATGGTGAAACC
CCATCTCTACTAAAAATACAGTATTAGCCAGGCATGGTGGCAGGCGCCTGTGATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCATG
TGAACCCAGGAGGTGGAGGTTGCAGTAAGCCGAGATTGTGCCACTGCACTCCAGCCTGGGCCACAGAGTGAGACTCCATCTCAAAAAAAA
AAAAAAAAAAAAAAAGAAACATCAGCCTGTATATTCCAGTAGTTCTCACAGAAGAATGAAAATCCGTGCTGTGCAAATAGATCAGTAGTG
AGTGAGTGTTAAGTGAAAGATGAGCTAGGTTGAAGAAAATATACATTTTATTGATGAGCCACTTTGCTATCTCTCCTTCCTTCCTCCTTC
CTTCCTTCCTTCCTTCCTTCCTTCCTTCCCTTCTTTTCTTTTTTCTTTTCTTTTCTTTTCTCCCTCCTTTCTTCCTTCCCTTCCCTTCCC
CTCCCCTCCCCCAGGCTGGAGTGCAGAGGCACGATCCTGGCTGACTGCAAACTCTGCCTACCAGGTTCAAGCGATTCTCCTGCCTCATCC
TCCCTAGTAGCTAGGATTACAGGCATCTGCCACCACGCCCAGCTAATTTTTGTATTTTTACAAAATACAAAGAGACGGGGTTTCACCATG
TTGGCCAGGCTGGTCTCTAACTCCTGACCTCAGGTGATCCGTCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGTGTTACTGCC
CCAGCCTCCTATTTCCTTTTCGAAAGTAGCAGTTTGGTTTATTCTCGTTTGCTAAGTAATTGTTTGAAATATTTTTCAGCCTCTCCTGCT
CCCTCACAAAAATTCACCTGTCATTTTAATGATAACAGCATGTTAAAAACTTGGAAGTCTTTATCCCAATATAAGAATTATCTTGAAACA
AAAATCTAAATTACTTTTAAAAATTCTCTTAACTCTGCATTTAGTCTCCTATTATCTAGATCTCTGAGTCCAGGATAACTCCAGTTATCC
CCAGTTGGATCATGTGTGATTTATCTGAGAAAGCATCCACAACCCACAGCTAGTGGAAACCGAGCTAGTTTACAGCCACGTGGATAAGAA
CATCTTTGTTTCTAAAGTGAGAGGAAAGTGCTTGGTATCTTGCTTTTTGCTGAGGGCAAAATAACAACATGAAGACAAAGTGCTTTTTGT
TGTCTATTCATGAAACTGTAGAAGAATATTTTGAGTTTTTATTCTTATATTATGAAGGGATTCTTTGCCTAGCAGTGGCCGTCAAACTGA
TGTAGCATTGTACTTCTCAACAGTGAAGCCTGTGTAATACCATACAGTAGGATGAAAGACTATTCTGAGCAAAATCAAATGGGATGTCAG
AATCTTTGAAAATTATTTTATCATTTTTTCTATTTTTTCATTTTTATAAATTAGAAGGATTTTCCATTCAATAAGGATAATCTCTCTTCC
TATCATTCTGTCAAAATGGCAGTTTCTTTTGGTAATTATCCAACCTAGTTTCATTACATTTAGAAGGAGGTTTCAGAGCTTATTCTTGAT
AACTATAATAATGATTTGAATGTTTTATATCATGAAGTTTTTTCTATGAGGAAGGCTATTCTCAATGTATCTGTCGTCTAATTTTTTATT
TTCTATCTATAAAGAATATTTAAATAATAATTGGTGTATGTTCCTTTTGTTGAAAATGTTTTATTGTCCAGTTTTAACACAGAAGTGGTC
TAAAGTTTTGCAGCAAATGCTGTTCAGTTCCCAGAAGCCTAAAAAACATAACATAATATGCTAACAGAGCTAATTTCCACCCAATCCCTC
AAATTACCGAAGTATTAATATTTAGCTTCCTTTCTAGAAAACAAGGGGCAGCACAAATGGGGTGGCATCCATCTCTTTTAAATCACTGAT
GATTTTCTGGGGAAGTATATATAGATGATTTTATTTTTTAAATAGCCTTTTATCAAACCATTTCACATGTATTATCTATATGACTATAGA
AACTTATAAAACATTTAATTCATGTTGACTTAAAACATGGGCATCCTTGGATTCTCCACATTGACTGAAATGATAGAGAAAGGGACATTT
GTTTGAGAAACAAGAGACCTGTACCTAATTATGGCAAGTATATGAGTTTTGGTGATTGTGGGGGGTTATAAATGTTTTCCTATGATAGAT
AAATATATAGATATAGATCAGGAATTACTTGATGTCTCTTCAGAAGTTTTCTGTTTTCTTATAATTTCCAGTAATACTCTGTAAGACTCG
GTTTGCATGCTGTGTGTGTTTGCATGAGTATAGAAACCTAAGAACATAATGGAAGGCTATTAAGGCAAATTCATTCCTAGAAAGTGGAGT
GGATCATTGGGATAAGAAATAGCCTAATTATAAACAAATATGCAGGCAGAGGGAAGTCCTAATACAATGAAAACTTGCATTATCTAAACA
GATGTTCCCAAAGCAATAGTTTGCCTAAAATCCTCTGTATTACATGATTATTCAGTAAAAGAGTAAACAAATATCTAATTTATTTTCTAA
TTGTCCTTCCCTTCATTGAGTATTAACTAGGTGCATAATGTAGTTGTATATGTTTACTAGTAAAGGGAAAAACACTTATTTTCATTTTGA
GACTGTTTGGCTATTACTAAAGCTGAGAAAGTGATTTTAGGTCGCCAAGGATACTATGATTTGATGAGATGAGAAGAAATCTGCGGTGGC
TGAAAATCGTGACCAACTTGGTGTTATCTAGATCTGCTTTATCTAGTTTGCAAGCCATAGGCTCAATTTTATGTCCTTCTTACTTACACA
CAGTAGCCCCACACAGTTTTGTTTTAAATGAAGGCAAAAGTAGACATTTTTAAAGTATATTCAACATTGTGCCATTATTTACCTGATAAA
GGTGAAATCAGAGGTGTCCACGGCCTCAAAGTTTGGGCCCATGGGACTATCAAATCCGAATTATATCTACTTAGAGCTTAGAGGAAGAAT
TAGGTATCATGAGAAAAGCAACTCCTACTTGAGAGAAAGAAGACTACCAAAGCATGTTGAGGCTTTAACATGGGAGACTTCCAGGTAGGC
GTTAACACTTGAGTGGTAACTAGCTTGATGAAGGAAAATAATTACTTTAGCAGTTATGTTGTAAAATTAATAAAAAGGACTCATGTTTAT
TCTGGTGTATTTGTCAACCCATGGGTAGTGATTACTCCGTGTACATTCTATAGTGTGTGTATTTTATTTAGTGTCTTAATATATAGTCTT
TATATAGTATCTTAATATTATTTACTGTTACTTCTAGTCATTTATGTAGTATATTTTACTGCAAAATTTGTAGCACTTTACTAATATTAG
ATCATTATTTTCCCTCTTCCCCTCTACCTTTCTGGCATTTTCTGTTATCTTAGAGTCAGGAATCTAAAGGTCTAAGTCTAGAAATCTGTT
GGAAGCTGGGTTGGAGCTACTGGATATGAGTTACTTTTTACATGTCTCCTTAAGAAGACTCTTTTATAATGTAATACTTAGAAGCCAAAT
CCTTTCAAACGCAAACACCCTTGAAACTTGATGCTTTCTGAAGTTGTATTCATAAAAATTATCCCATCTTACAGTTAATCAGAAGATGTT
CTTACCTTTGGTTTGCCTGCCTCCTGAAACACAAACCTGCAGATTGCCCCTAACTTCAGCAGTGCCTCCGTCACTGCATGTACCTAAAAG
ACAGGAAAGCCAAGTTCTGGGAGCTGTCAAGTCGGAGGATCAGGAAAATGGTGGGGAAGAGGTGACTGGAAAGGCAGGCACTAAAGATGG
CAGGCTGCAAAAGCATTCTGAGTTCCCCTGTAACAGATAGGTTTTATGAACTCAGCTGTTTTCTTTTTTCTTTTTTTTTCTTTTGAGATG
GAGTCTCACTCTGAGTCTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGCACAATCTCAGCTCACTGCAGCCTCCACCTCCCGGTTTCAAG
TGATTCTCCCACCTCAGCCTCCCGAGTAGTTAGGATTACAGGTGCCCACCACCACGCCCAACTAATTTTTGTATTTTTAGTAAAGACAGG
GTGTCGCCATATTGGCTAGGCTGGTTTTGAACTCCTGACCTCAGGTAATCCACCCGCCTCAGCCTCCCAAAGTGCTGGGATTATTATAGG
CGTGAGCCACCATGCCCAGTGAACTTGGCCATTTTCTTACATTCATATATAGCAAAGTTTTCAACTTGTCTACCGAGAGACTTTCTTTAG
GAGCCAGGACTTCTACATTTGTAACTTGAGTATATTAATATTCAAATCATAGTTCAAAAATACTGAAATACTTGTTTATTATGTTACATA
AATATGGACACAATTACTGCCAAAGAATAGAGAGATTTGCTTATGAGAACATTCTGTCATTTGTTCTGTTTGTAGATGAGAGACATGCTT
TTAAAGTACAAAACGTTTCTCTTCTACCTTACCCCCTGTTCTACTGACGTGCTTTGCATGAGAAGCTCATCTAGAAGAGAGCAACGCTGG
AATAGAGAAGTCTAGACCCTGGCCTTTGAGGGAAAGGACTGCTTTTTTTCTCTCCCAAATTAGAAAATTAAAAGTGAAACATAACACATA
AGGACGAAATACAATGTTCTGAATATCTTCCACTAATTAATTGTTGAATGATTAAGTCTCTAAGTATCTTAACTTCCATTGTCTTCTTGT
TAACCTAGACAAGAGTAGATTATTCAGTAGCCACATGTGACAGTTAAAATTAAGTAAAATTAAAACTATAGTTTCTCAGTGGCCTAGCCA
CATTTCAAGTGTTCCACAGTCACATGTGGATAGTAGTTACCTATCAGACAGTACAGGTATAGAACATTTCCAGTATTGCCAAAAATGCTA
TTCAACAGCACTTTTATTGCCCAGAGAGAAAATAAGGACAAAATAAAGGCAGTGAAGTAACTTAAGACAACTCTGAGATTTTACCACCAT
ACTTAGAGAAAGTTTTTCTGTTATAAAAATTAATACTAATCCTTTTTAAAGACCTTGGAAAAAATCAAAACCCCATTCCTTTAAGCTAGT
CTTCAGTATATATTTTTCTAAGAACAGATTCTCAATACTTTATTTTTCAAGTGATAAAATCATTTTATAAATCATTTCTTAATATCTTCA
GTGTTTTTTCCCTTTTTATGTAAACTCTTTTAAAATTGATATTAGCTGGGCATGGTAGCTCATGCCTGTAGTCCCAGCTACTCCAGAGGT
CGAGGCAGGAGCATCGCTTAAGCCCAGGAGGTTCAGGCTGCAGTAAGGTCTGATCACACCTGACTGCACTCCAGCCTGGGTGGCAAAGCA
AGACCCCTGTCTCTAAAAAAAAATAATATAAATTGATGTTATATAGTTAACATTTATCAGGCAAATTCATATGAATGCTTATTTCAAATA
AAGATTGATAGATTTAATGATATCCTTCCTTTTAAATTTATATAGATCTAATGAACATTGCCAACAGTTTTTTTTGTTTCTGTCCCTTAA
ACATTTCCCCTGAAAGTCCACCTCAAAGGTACATCAAGATGCAAACAATTTTTTTATCTTCATAACTTCCTGCTCTTATTAACTTGTATT
ATGAATCAAATTAAGTTTTATGTATAAGGCATTTACTATTCCAGTGACTTAGCTAATGAAAACATTTAAAAATATGTATTAATTTACTTG
GCCTGCTACTAAAGTGCTTAACATAACTAAATGGATCTATAGTAACATGTCTAAATTTTTTAATGGAAATAAGGGACTAACCATAATCCT
TTTGAGTCAGCTTGGTGCTTACAATTATTTTGTTAGGAAATCTTGATGCTTTCTTCTTTCTCTTTAAATTTTTGTAATCAAGCAACAGAC
TTGATCCAGCAGTGTCGAATTCCAAGCAAGTTATGATGATTCTTATTGTAGTTCAAGTACAGATGAGTAAGTGGTGTGACTTCAGTTTAT
TATCTTCTTGGTGACCTACTTTAGTATGTGTTCTGTAGCGATTCATATTAGTTAAGGGACGTTTTCAATATGCTTGAAATAAGAAATAGC
ATTTTACTCTAAATACAAGAAATGACTGTACACAAATGCTAATCAGTGATTTGGGGCCTTTTAATGTCTTTAACAGCAATCTTTTATTTA
TTTATTTATTTATTTTTGAGACGGAGTCTTGCTGTGTCACCAGGCTGGAGCAGTGGCACGATCTCGCCTCACTGCAACCTCCGCCTCCCA
GGTTCAAGCTATTCTCCTGCCTCAGCCTCCCAAGTAACTGGGACTGCAGGCACATGCCACCACATCCAGCTAATTTTTGTATTTTTAGTA
GAGACGGGGTTTCACCTTGTTGGCCAGGATGATCTCGATCTCTTGATCTCGTGATCTGCCCGCATTGGCCTCCTGAAGTGCTGGGATTAC
AGGCATGAGCCACTGCGCCCGGCCCAAATCTTTTATTTTTTAACAGCCTTAGTTATTTATAATTCAAATGCACTAAAATATCATCGCTGT
CATGAACTTTGCTGTTTACAGGTTCTGTGTAATTCAGAATGCTTTGTACTTAGAAAATAATTTCTAGGCTTATCTTGTTTTGCAGTTTTC
ATGTTTTGACAATTGCCCACCATTTACAATACTCAATTTTTGATTATGAAATGAATAGTAAAATTCAAACATATCTAATAATAATTTGCC
TTAGTTTGATTAATAAATTATATCAAAAAACTTGGGGATAGAAAGAGGCTTTTTTTTCCCCCTGTAGTATTTTTAAAACTTTTTAGATGA
GCTGGATGAAACCTTAGTACATTGGAGCTGGAGTTGTATTGAGTACAGCCCCAACTCTGAAGCCTTATATTCATGTCTTAAGTACCATTG
ATTGTTCTGTGAATTGTTGTTAGTTTCATATTTGACATTGTAGTAATCCACCTTGCATTTTAGTCTTTGCAAAAAGGATATTGCTAGGTA
TATTCTTATTTCTGATTGAGTATTGAATTTACATTTTTCAGAATTTCATTCTTTGTCATTATAATCCAAAAACAATGTCCACATCAGACT
TGGAACTTCTCACTTCAAAAATGAAATACAGATTTAGCAGTGTTGTACATAATGATGTCCAAGCATTTTTCCACCTGTTTACTGAGTTTT
CCAACCATTTACTATGTGTTGAGATTGGTGGGTTTTCTGGCTGTTTTTCTGAGGTGAATGACTTGTTACAGAGCCTCAGTAAGAAATTTC
AACTAAAATCACAAAAACATAAAGTCCAGGAAACCACCAGAAGATGGATTTTTAGTGTTTTTGAAATCTTGTATTTCCTTTTGATATCAT
TTACTCATTTTAATTTTACGACTGCCAACTTGTTACGGTATTAATTATATGTATGTGTTTATATGTATGCATATAATATATGTATATGTA
TATGAAGAATAAAGTTAAGATTTGGTCAAACTATATTTTCCCATTCAAGTACAAAAATGTTTTCAAGGCTGCAAAAAGTGTACAGTTGTT

>In-frame_ENST00000326197_ENST00000307602_TCGA-HB-A5W3-01A_SCMH1_chr1_41578955_-_HOOK3_chr8_42761316_length(amino acids)=710AA_start in transcript=982_stop in transcript=3114
METTCSLLAPKIQTFNVDAPCQTVEDLTNGVVMAQVLQKIDPAYFDENWLNRIKTEVGDNWRLKISNLKKILKGILDYNHEILGQQINDF
TLPDVNLIGEHSDAAELGRMLQLILGCAVNCEQKQEYIQAIMMMEESVQHVVMTAIQELMSKESPVSAGNDAYVDLDRQLKKTTEELNEA
LSAKEEIAQRCHELDMQVAALQEEKSSLLAENQVLMERLNQSDSIEDPNSPAGRRHLQLQTQLEQLQEETFRLEAAKDDYRIRCEELEKE
ISELRQQNDELTTLADEAQSLKDEIDVLRHSSDKVSKLEGQVESYKKKLEDLGDLRRQVKLLEEKNTMYMQNTVSLEEELRKANAARSQL
ETYKRQVVELQNRLSEESKKADKLDFEYKRLKEKVDSLQKEKDRLRTERDSLKETIEELRCVQAQEGQLTTQGLMPLGSQESSDSLAAEI
VTPEIREKLIRLQHENKMLKLNQEGSDNEKIALLQSLLDDANLRKNELETENRLVNQRLLEVQSQVEELQKSLQDQGSKAEDSVLLKKKL
EEHLEKLHEANNELQKKRAIIEDLEPRFNNSSLKIEELQEALRKKEEEMKQMEERYKKYLEKAKSVIRTLDPKQNQGAAPEIQALKNQLQ

--------------------------------------------------------------
>In-frame_ENST00000372596_ENST00000307602_TCGA-HB-A5W3-01A_SCMH1_chr1_41578955_-_HOOK3_chr8_42761316_length(transcript)=15270nt_BP=1129nt
GCGGAAACATGGCGGCGGGAAGAGAGTGAGCCGCCCCGCGCCCCCGCCGCGCCCTCAGATGGAGAAATTAGCATACAAAGAAACTGACTT
GTCAGAAGTCAGAGCAAGGTATTGGTGGATCCAGGGATAAATCCCAAACTTCTTAACCCCTAGACCGGTTTTTAGTCCATTGACTATGCA
GCCTAATGTGATAGACTGGAGTGATGTTAGAAAACACAAATATGGTCACCTATCAGAGTCTGCATCCCAATATCAAGAAGCTGCTGACAT
CCTGGATCTAGGGTTGTAAAGAAGATTACATGAGCTAATGGATGTGAAAACATCTTAAAAACTCTCAAATACTTTTCAACTTTGGAGGAT
TATTATGATTTTCATTCTGTTCAGCGGCTATACTCAGACTTTACTCTAAAAGTCAAATCTTCTGACATTCTTTGAAGTGAAGCATTCTAT
GAATGTGAGCTGAAGAAATGAATGAAATGAAATAATGCAGGTCATTTTACCTGGGACAAATACCTAAAAGAAACATGTTCAGTCCCAGCG
CCTGTCCATTGCTTCAAGCAGTCCTACACACCTCCAAGCAACGAGTTCAAGATCAGTATGAAATTGGAAGCACAGGACCCCAGGAACACC
ACATCCACCTGTATTGCCACAGTAGTTGGACTGACAGGTGCCCGCCTTCGCCTGCGCCTTGATGGGAGCGACAACAAAAATGACTTCTGG
CGGCTGGTTGACTCAGCTGAAATCCAGCCTATTGGGAACTGTGAAAAGAATGGGGGTATGCTACAGCCACCTCTTGGATTTCGGCTGAAT
GCGTCTTCTTGGCCCATGTTCCTTTTGAAGACGCTAAATGGAGCAGAGATGGCTCCCATCAGGATTTTCCACAAGGAGCCACCATCGCCT
TCCCACAACTTCTTCAAAATGGGAATGAAGCTAGAAGCTGTGGACAGGAAGAACCCTCATTTCATTTGCCCAGCCACTATTGGGGAGGTT
CGGGGCTCAGAGGTGCTTGTCACTTTTGATGGGTGGCGAGGGGCCTTTGACTACTGGTGCCGCTTCGACTCCCGAGACATCTTCCCTGTG
GGCTGGTGTTCCTTGACTGGAGACAACCTGCAGCCTCCTGGCACCAAAGATCCAGACATTTAATGTGGATGCACCATGCCAGACCGTGGA
AGATTTAACGAATGGGGTTGTGATGGCCCAGGTTCTTCAAAAGATAGATCCTGCATATTTTGATGAAAATTGGCTAAACAGAATCAAAAC
TGAAGTAGGAGATAATTGGAGGCTAAAGATAAGCAATTTAAAGAAAATTTTAAAAGGAATCTTGGATTATAATCATGAGATTTTAGGACA
GCAAATTAATGACTTTACCCTTCCTGATGTGAACCTTATTGGGGAGCATTCTGATGCAGCAGAGCTTGGAAGGATGCTTCAGCTCATCTT
AGGCTGTGCTGTGAACTGTGAACAGAAGCAAGAGTACATCCAAGCCATTATGATGATGGAGGAATCTGTTCAACATGTTGTCATGACAGC
CATTCAAGAGCTGATGAGTAAAGAATCTCCTGTCTCTGCTGGAAATGATGCCTATGTTGACCTTGATCGTCAGCTGAAGAAAACTACAGA
GGAACTAAATGAAGCTTTGTCAGCAAAGGAAGAAATTGCTCAAAGATGCCATGAACTGGATATGCAGGTTGCAGCATTGCAGGAAGAGAA
AAGTAGTTTGTTGGCAGAGAATCAGGTATTAATGGAAAGACTCAATCAATCTGATTCTATAGAAGACCCTAACAGTCCAGCAGGAAGAAG
GCATTTGCAGCTCCAGACTCAATTAGAACAGCTCCAAGAAGAAACATTCAGACTAGAAGCAGCCAAAGATGATTATCGAATACGTTGTGA
AGAGTTAGAAAAGGAGATCTCTGAACTTCGGCAACAGAATGATGAACTGACCACTTTGGCAGATGAAGCTCAGTCTCTGAAAGATGAGAT
CGACGTGCTGAGACATTCTTCTGATAAAGTATCTAAACTAGAAGGTCAAGTAGAATCTTATAAAAAGAAGCTAGAAGACCTTGGTGATTT
AAGGCGGCAGGTTAAACTCTTAGAAGAGAAGAATACCATGTATATGCAGAATACTGTCAGTCTAGAGGAAGAGTTAAGAAAGGCCAACGC
AGCGCGAAGTCAACTTGAAACCTACAAGAGACAGGTAGTAGAACTACAAAACAGATTATCCGAAGAATCAAAGAAAGCAGATAAACTAGA
TTTTGAATATAAGCGGCTAAAAGAAAAAGTTGACAGTCTTCAAAAAGAAAAGGACAGGCTGAGAACAGAAAGGGATTCTCTGAAGGAAAC
CATTGAAGAGCTTCGTTGTGTACAAGCTCAAGAAGGGCAGCTCACAACACAAGGGTTAATGCCTCTTGGAAGTCAGGAGTCTTCAGACAG
TCTAGCTGCAGAGATTGTTACACCTGAAATCAGGGAGAAACTTATTCGTCTTCAGCATGAGAATAAGATGTTAAAGCTTAACCAAGAAGG
TTCGGACAATGAAAAAATAGCCTTATTGCAGAGCCTTCTAGATGATGCAAATCTACGCAAGAATGAACTGGAGACAGAGAATAGGCTGGT
GAATCAAAGACTTCTGGAAGTACAGTCACAAGTTGAAGAATTACAAAAATCTTTACAGGATCAAGGCTCAAAAGCAGAAGATTCAGTCCT
TCTAAAAAAGAAGCTTGAAGAACATCTAGAGAAGCTGCATGAGGCCAATAATGAACTACAGAAGAAGAGAGCCATTATTGAAGATCTCGA
GCCAAGATTTAACAACAGCTCCTTAAAAATTGAAGAATTACAAGAAGCTTTACGAAAGAAAGAGGAAGAAATGAAGCAAATGGAAGAACG
ATACAAAAAATACTTAGAGAAAGCCAAAAGTGTCATCCGTACTTTAGATCCTAAACAGAATCAAGGAGCAGCACCAGAAATACAAGCTCT
TAAAAATCAGCTCCAGGAACGAGACCGACTGTTCCACTCATTAGAGAAAGAATATGAGAAAACAAAGAGTCAGAGAGAGATGGAAGAGAA
ATATATTGTTAGTGCCTGGTACAATATGGGAATGACCCTGCATAAAAAGGCAGCTGAAGATAGACTGGCAAGCACAGGCTCAGGGCAGTC
ATTTCTGGCGAGGCAGAGGCAAGCGACCAGCAGCAGAAGATCATACCCAGGCCACGTGCAGCCGGCCACAGCAAGGTAGAGAAGTTGTGC
CGCTCAATCACAGACACCTGCACCCACAACATACTTCTGTTACACACAAGAACATTTCAGGAAACTCAGCCAGCTTATTTTTTGTTTCTC
TTCTATGTCAATACTTAGTGTTTCTCATTTTGAGGACTTTTTCTCTCTCCTGTATCTTTGTTTTAGTTTCTTTGGTTTTTATTTTGTAGT
CCTTTCAGTTATTTTTAATGTGCCAAAAATTTGTACATGTTCAATTAAAAATGTTGTATAATAGTGTAATACTTTTCTTTGTATGAAAAT
GTCCTCTTCTTCAAAGGTATAGGCTTTGTAATGAATTAGATTTTCTGCCAATAATTGATATACAATTTATATTCTTTATTGTGCCTGTGT
GTTACCATGCTAAGAATGTCTTTGTTTAAAGGGAATTAATCTTTTTATGATGTATTAATCTGTGTTTTCAATTGTTTTCCAAGTACAGTT
CAAATAACTTGCATATTTACTATACAAAATGGTTGACAAGTGTTCTTTTTGCAAAGACTTGAATACATTGGCAGAGGTGCTAATCACATC
TTCCCTAAGGCACCTGGAAGAATTATTTGAGGAAAAAATGAGTTTTCACATTGTTTTATAGGAAATTAAATTTGTCCAAAGATTTGGAGA
CTATTTTTAAAACATAAATACATAAAATTTCATTATTTCCTGCTATCTTGTTTGCTGGCAGAAGTGAATGTTTGGTGAGGTTATTTTGGG
ATAAATTACAAAAGAAAAAAAATTAGACACTGCATTAATTTCTTGTTCTTTTGGAATATCTTAGTAACTGAGGATCATTTTCTAACAATG
TGGTTGACATACCTTCAGTTGCTTTCCACATCTAAAAGAGTTATCTTTCATATATGTACAAGTTATTGGTAGTCTTATTTTTGGGCTGTT
TGTTGACTTATGCCCCATTTGTTTTACTTGTTCTTTAATATAAACCCTTCCATTTTTTAACAATTCCTAACACTTGATATCTTAATATCA
GTCACTAACATTAGTAACTTCTTGTATGTTATATTATGGCAGATCTCTTTACGTTTTTTCTCACATCTATCTGCTAGTCCAGGAATTTGT
TACTAAATAGATTTTCTTGGATATTTGGTTGCCTCAAAGTGCTTACATTTGTTAACAGATTGTAAACCACATTTATTTACATTGATGAAT
GGGCTGTTGAATAATCATTGTAAAGCACTTTGTATATATAAGGTGCTATATAAGTGTGAAATATCATTCATTTATAAATGAAATGCCTTC
TAACTTTCCATATTGACTTATGTATTTGGTCCCAAATTATATTTAAGTCTTTTTTCTTGCAACGTAGCCCATTTTTTGAAAGCAAAACAT
TTCTGAAATTAGGTCATGGTTTTTTTGTTTATTTTTAGGTTAGGTCACTTAATATAGGAGGATGTTTTCTCATGTACTTGCTATTTGCAA
GTTCAGGTTTCATTTGGTTCTTTATGTTAAATACGAATAAGTAACCTCAAATCAAGCTAAATGTAATTAAGAATTTTCAGCAACTATATT
CAAGTGTTTGATTTTTAAATTCTTTCTTTCTTTTTAATAAGAAAGATGACCTAAAAATCAGTGGTATTTGTTTGTCCTCAGAAGCCGTAG
TTGAAGAAAGATATTAGAGTATACACAGAACTGGAGCCATACATTGTGCTAATTTTTTACATTAAGTACAGAAGTCTGAGCACAGCATGA
ATGCTTCTGCCTGACAGGACCACAAAGCAGCAGAAGTTAGGGATAAATGGAGATAGCCATGAGTAGAACTGCTGTAGGGCTTCAGGAGGC
TACGCAGACCTGATCAACTGCAAAGTTTCCAAAGTAAAAGATTAAAAACTTTCAGACGGTTCTTACCTCTACCCGTGTTTCACAAATAGC
CTGAGGATCCAACTATTTTTAAAGCAAATTGGGGCCAGACGTGGTGCCTCACGCCTGCAATCTCACCATTTGGGAGACCTAGGTGGGGGT
GGATCACTTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAATTACAAAAATTAGCTGGGCATGGT
GGCATGTGGCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAGTCACTTGAACTCAGGAGCCAGAGACTGCAGTGAGCTGAGATCG
CACCACTGCATTCCAGCCTGGGCGACAGAGTGAGACTCTGTCTCAATCAGTCAATCAATCAATCAATCAAATTGGAATATGAGCACTAAC
CTTGGTAAGTTAAAATTTTGGGAAAATTGTACCTGCAGAATATGATGGATGAAAACAACAGCCAGGTGCAGTGGCTCACGCGTATAATCC
CAGCACTTTGGGAGGCCGAGACAGGCACATCATCTGAGGTCAGGACTTCCAGACCAGCCTGTCCAACATGGTGAAACTCCGTCTCTACTA
AAAATACAAACAATTAGCCAGGCATGGTGGTGTGTGCCTGTAGTCCCAGCTACTTGGGAGGGTGAGGCAGGAGAATTGCTTGAACCTGGG
AGACAGAGATTGCAGTGAGCCGAGATGGCGCCATTGCACCCCAGCCTGGCGACAAGAGCGAAACTCTGTCGCAAGAAAAAAAAAAAAAAA
AAAAAAAAAAAAAACAGTCTGTGAACTACTCACTGAATGAATTTTGTTCTGTGAGATGAGAGGTTTTCATTTTCATTTTCTATTTACAGC
CCCAGTCCTAATCTCCTACCCATCCACCTACCCAGATATTTTTTCTCTATCTGGGTTGGAAAGGCCCCAGGCTTTTAGAGGGGAGTTTTA
CTTCTGACTTTTTTTTCCCCCCGAGACGGAGCCTCGTTCCGTCACCCAGGCTGTAGTGCCGTGGCATGATCTCGGCTCACTGCAGCCTCT
GCCTCCCGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCAGAGTAGCTGGGATTACAGGTGCCCACCACCATGGCTGGCTAATTTTTGTAA
TTTAGTAGAGATGGTGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCGTGATCTACCCACCTCGGCCTCCCAAAGTGCTG
AGATTACAGGCACGAGCCACCGCGCCCAGTCGTACTTCTGACTTTTCTTCAGCATCTGTTGTATGCTATTATTTTGATGTTTACATTTAT
AATTTTCTTTCTTTTTTTTTTTTTTGTGAGATGATGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTGCAA
GCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCTGAGTAGCGGGGACTACAGGCGCCCGCCACTACGCCCGACTAATTTT
TTGTATTTTTTAGTAGAGACGGGGTTTCACCATGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCACCCGCCTCAGCCTCCCA
GAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCAGCCTACATTTATAATTTTCATTCTCTTTTACCTATAAAATTCAGTGTATTAGTT
TCATTACATAGGAGAAATTATATTTCTAAACATTTTATGATGTTTAAAAACAAAACAGGCTGTTGTAAAAAAAAAAAAAAAAAAAACTTC
TGAATATACTTTAGGTATCAGAAAGCCAAGAATAAAATTTAGCTCTAACGGTGGCAACTCCATGTCCGGTGTCCAGCTTTGGACAGGGTT
TATGACGTTTCTGTTTCTCTAGTAATGATTAATGATTCCTCAGGAGATTCGTGATGTTGTCTGGTCTATCTGGAAATTTAAAGTCACTAG
GAGCTTTGCCTCATCGTGAGTGATGCTGTGCTGTATTTTTACAAACTCTCGCATACAGCACCTTCCTGGGGCCACGTTGGCTTGTGCAGT
GGAGCTTGTCCAGGCACCAGCATGGAGCAAGTACAGGGTTGCTGTGTTGGGTTGGAGCACACTGTCACCACAGTGTCTGAAGTCTTATAA
ACAGGAAGATCATTTTCTGTTTTCCTTCTAACCAGGGTGAGAAAATACAAAGTAAAGAACTAAAGAATATTAAAACCTAGCATTTATGTT
CCACAGTGTGTATTTCAGAAGTTTGTAATCCAGAAAATATAGTAGTGTATAATATCTGAAAAGAGAATCAAGTATACAATTGTACATATT
TTTAAAGAACTTTGAAAAACTCCGTCATATCTTTTACCATTTGTCTATTTGATAGTAATGCAGAAAAAAGTCCCTAAAGACCCTGTGTTC
CAAAATTTACCAAGATTGACATTTCTATTAGACATCCTTAACCTAAGTGTTTTAATTAGATTATTAGACTATAATAAGGATGAAATTGCT
GTCTGTAATTTTGTTGAGGTTTTATTGTTAATATAATAAAAGCTCAACTGTACAAAATTAAGCTAAATGTTATCCAGTCAGAAACATCAG
CCTGTGGCCAGGTGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGCGGATCACCTGAGGTCAGGAGTTCAAGAC
CAGCCTGGCTAATATGGTGAAACCCCATCTCTACTAAAAATACAGTATTAGCCAGGCATGGTGGCAGGCGCCTGTGATCCCAGCTACTTG
GGAGGCTGAGGCAGGAGAATCATGTGAACCCAGGAGGTGGAGGTTGCAGTAAGCCGAGATTGTGCCACTGCACTCCAGCCTGGGCCACAG
AGTGAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAAAAGAAACATCAGCCTGTATATTCCAGTAGTTCTCACAGAAGAATGAAAATCCG
TGCTGTGCAAATAGATCAGTAGTGAGTGAGTGTTAAGTGAAAGATGAGCTAGGTTGAAGAAAATATACATTTTATTGATGAGCCACTTTG
CTATCTCTCCTTCCTTCCTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCCTTCTTTTCTTTTTTCTTTTCTTTTCTTTTCTCCCTC
CTTTCTTCCTTCCCTTCCCTTCCCCTCCCCTCCCCCAGGCTGGAGTGCAGAGGCACGATCCTGGCTGACTGCAAACTCTGCCTACCAGGT
TCAAGCGATTCTCCTGCCTCATCCTCCCTAGTAGCTAGGATTACAGGCATCTGCCACCACGCCCAGCTAATTTTTGTATTTTTACAAAAT
ACAAAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCTAACTCCTGACCTCAGGTGATCCGTCCACCTTGGCCTCCCAAAGTGCTG
GGATTACAGGCGTGTGTTACTGCCCCAGCCTCCTATTTCCTTTTCGAAAGTAGCAGTTTGGTTTATTCTCGTTTGCTAAGTAATTGTTTG
AAATATTTTTCAGCCTCTCCTGCTCCCTCACAAAAATTCACCTGTCATTTTAATGATAACAGCATGTTAAAAACTTGGAAGTCTTTATCC
CAATATAAGAATTATCTTGAAACAAAAATCTAAATTACTTTTAAAAATTCTCTTAACTCTGCATTTAGTCTCCTATTATCTAGATCTCTG
AGTCCAGGATAACTCCAGTTATCCCCAGTTGGATCATGTGTGATTTATCTGAGAAAGCATCCACAACCCACAGCTAGTGGAAACCGAGCT
AGTTTACAGCCACGTGGATAAGAACATCTTTGTTTCTAAAGTGAGAGGAAAGTGCTTGGTATCTTGCTTTTTGCTGAGGGCAAAATAACA
ACATGAAGACAAAGTGCTTTTTGTTGTCTATTCATGAAACTGTAGAAGAATATTTTGAGTTTTTATTCTTATATTATGAAGGGATTCTTT
GCCTAGCAGTGGCCGTCAAACTGATGTAGCATTGTACTTCTCAACAGTGAAGCCTGTGTAATACCATACAGTAGGATGAAAGACTATTCT
GAGCAAAATCAAATGGGATGTCAGAATCTTTGAAAATTATTTTATCATTTTTTCTATTTTTTCATTTTTATAAATTAGAAGGATTTTCCA
TTCAATAAGGATAATCTCTCTTCCTATCATTCTGTCAAAATGGCAGTTTCTTTTGGTAATTATCCAACCTAGTTTCATTACATTTAGAAG
GAGGTTTCAGAGCTTATTCTTGATAACTATAATAATGATTTGAATGTTTTATATCATGAAGTTTTTTCTATGAGGAAGGCTATTCTCAAT
GTATCTGTCGTCTAATTTTTTATTTTCTATCTATAAAGAATATTTAAATAATAATTGGTGTATGTTCCTTTTGTTGAAAATGTTTTATTG
TCCAGTTTTAACACAGAAGTGGTCTAAAGTTTTGCAGCAAATGCTGTTCAGTTCCCAGAAGCCTAAAAAACATAACATAATATGCTAACA
GAGCTAATTTCCACCCAATCCCTCAAATTACCGAAGTATTAATATTTAGCTTCCTTTCTAGAAAACAAGGGGCAGCACAAATGGGGTGGC
ATCCATCTCTTTTAAATCACTGATGATTTTCTGGGGAAGTATATATAGATGATTTTATTTTTTAAATAGCCTTTTATCAAACCATTTCAC
ATGTATTATCTATATGACTATAGAAACTTATAAAACATTTAATTCATGTTGACTTAAAACATGGGCATCCTTGGATTCTCCACATTGACT
GAAATGATAGAGAAAGGGACATTTGTTTGAGAAACAAGAGACCTGTACCTAATTATGGCAAGTATATGAGTTTTGGTGATTGTGGGGGGT
TATAAATGTTTTCCTATGATAGATAAATATATAGATATAGATCAGGAATTACTTGATGTCTCTTCAGAAGTTTTCTGTTTTCTTATAATT
TCCAGTAATACTCTGTAAGACTCGGTTTGCATGCTGTGTGTGTTTGCATGAGTATAGAAACCTAAGAACATAATGGAAGGCTATTAAGGC
AAATTCATTCCTAGAAAGTGGAGTGGATCATTGGGATAAGAAATAGCCTAATTATAAACAAATATGCAGGCAGAGGGAAGTCCTAATACA
ATGAAAACTTGCATTATCTAAACAGATGTTCCCAAAGCAATAGTTTGCCTAAAATCCTCTGTATTACATGATTATTCAGTAAAAGAGTAA
ACAAATATCTAATTTATTTTCTAATTGTCCTTCCCTTCATTGAGTATTAACTAGGTGCATAATGTAGTTGTATATGTTTACTAGTAAAGG
GAAAAACACTTATTTTCATTTTGAGACTGTTTGGCTATTACTAAAGCTGAGAAAGTGATTTTAGGTCGCCAAGGATACTATGATTTGATG
AGATGAGAAGAAATCTGCGGTGGCTGAAAATCGTGACCAACTTGGTGTTATCTAGATCTGCTTTATCTAGTTTGCAAGCCATAGGCTCAA
TTTTATGTCCTTCTTACTTACACACAGTAGCCCCACACAGTTTTGTTTTAAATGAAGGCAAAAGTAGACATTTTTAAAGTATATTCAACA
TTGTGCCATTATTTACCTGATAAAGGTGAAATCAGAGGTGTCCACGGCCTCAAAGTTTGGGCCCATGGGACTATCAAATCCGAATTATAT
CTACTTAGAGCTTAGAGGAAGAATTAGGTATCATGAGAAAAGCAACTCCTACTTGAGAGAAAGAAGACTACCAAAGCATGTTGAGGCTTT
AACATGGGAGACTTCCAGGTAGGCGTTAACACTTGAGTGGTAACTAGCTTGATGAAGGAAAATAATTACTTTAGCAGTTATGTTGTAAAA
TTAATAAAAAGGACTCATGTTTATTCTGGTGTATTTGTCAACCCATGGGTAGTGATTACTCCGTGTACATTCTATAGTGTGTGTATTTTA
TTTAGTGTCTTAATATATAGTCTTTATATAGTATCTTAATATTATTTACTGTTACTTCTAGTCATTTATGTAGTATATTTTACTGCAAAA
TTTGTAGCACTTTACTAATATTAGATCATTATTTTCCCTCTTCCCCTCTACCTTTCTGGCATTTTCTGTTATCTTAGAGTCAGGAATCTA
AAGGTCTAAGTCTAGAAATCTGTTGGAAGCTGGGTTGGAGCTACTGGATATGAGTTACTTTTTACATGTCTCCTTAAGAAGACTCTTTTA
TAATGTAATACTTAGAAGCCAAATCCTTTCAAACGCAAACACCCTTGAAACTTGATGCTTTCTGAAGTTGTATTCATAAAAATTATCCCA
TCTTACAGTTAATCAGAAGATGTTCTTACCTTTGGTTTGCCTGCCTCCTGAAACACAAACCTGCAGATTGCCCCTAACTTCAGCAGTGCC
TCCGTCACTGCATGTACCTAAAAGACAGGAAAGCCAAGTTCTGGGAGCTGTCAAGTCGGAGGATCAGGAAAATGGTGGGGAAGAGGTGAC
TGGAAAGGCAGGCACTAAAGATGGCAGGCTGCAAAAGCATTCTGAGTTCCCCTGTAACAGATAGGTTTTATGAACTCAGCTGTTTTCTTT
TTTCTTTTTTTTTCTTTTGAGATGGAGTCTCACTCTGAGTCTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGCACAATCTCAGCTCACTG
CAGCCTCCACCTCCCGGTTTCAAGTGATTCTCCCACCTCAGCCTCCCGAGTAGTTAGGATTACAGGTGCCCACCACCACGCCCAACTAAT
TTTTGTATTTTTAGTAAAGACAGGGTGTCGCCATATTGGCTAGGCTGGTTTTGAACTCCTGACCTCAGGTAATCCACCCGCCTCAGCCTC
CCAAAGTGCTGGGATTATTATAGGCGTGAGCCACCATGCCCAGTGAACTTGGCCATTTTCTTACATTCATATATAGCAAAGTTTTCAACT
TGTCTACCGAGAGACTTTCTTTAGGAGCCAGGACTTCTACATTTGTAACTTGAGTATATTAATATTCAAATCATAGTTCAAAAATACTGA
AATACTTGTTTATTATGTTACATAAATATGGACACAATTACTGCCAAAGAATAGAGAGATTTGCTTATGAGAACATTCTGTCATTTGTTC
TGTTTGTAGATGAGAGACATGCTTTTAAAGTACAAAACGTTTCTCTTCTACCTTACCCCCTGTTCTACTGACGTGCTTTGCATGAGAAGC
TCATCTAGAAGAGAGCAACGCTGGAATAGAGAAGTCTAGACCCTGGCCTTTGAGGGAAAGGACTGCTTTTTTTCTCTCCCAAATTAGAAA
ATTAAAAGTGAAACATAACACATAAGGACGAAATACAATGTTCTGAATATCTTCCACTAATTAATTGTTGAATGATTAAGTCTCTAAGTA
TCTTAACTTCCATTGTCTTCTTGTTAACCTAGACAAGAGTAGATTATTCAGTAGCCACATGTGACAGTTAAAATTAAGTAAAATTAAAAC
TATAGTTTCTCAGTGGCCTAGCCACATTTCAAGTGTTCCACAGTCACATGTGGATAGTAGTTACCTATCAGACAGTACAGGTATAGAACA
TTTCCAGTATTGCCAAAAATGCTATTCAACAGCACTTTTATTGCCCAGAGAGAAAATAAGGACAAAATAAAGGCAGTGAAGTAACTTAAG
ACAACTCTGAGATTTTACCACCATACTTAGAGAAAGTTTTTCTGTTATAAAAATTAATACTAATCCTTTTTAAAGACCTTGGAAAAAATC
AAAACCCCATTCCTTTAAGCTAGTCTTCAGTATATATTTTTCTAAGAACAGATTCTCAATACTTTATTTTTCAAGTGATAAAATCATTTT
ATAAATCATTTCTTAATATCTTCAGTGTTTTTTCCCTTTTTATGTAAACTCTTTTAAAATTGATATTAGCTGGGCATGGTAGCTCATGCC
TGTAGTCCCAGCTACTCCAGAGGTCGAGGCAGGAGCATCGCTTAAGCCCAGGAGGTTCAGGCTGCAGTAAGGTCTGATCACACCTGACTG
CACTCCAGCCTGGGTGGCAAAGCAAGACCCCTGTCTCTAAAAAAAAATAATATAAATTGATGTTATATAGTTAACATTTATCAGGCAAAT
TCATATGAATGCTTATTTCAAATAAAGATTGATAGATTTAATGATATCCTTCCTTTTAAATTTATATAGATCTAATGAACATTGCCAACA
GTTTTTTTTGTTTCTGTCCCTTAAACATTTCCCCTGAAAGTCCACCTCAAAGGTACATCAAGATGCAAACAATTTTTTTATCTTCATAAC
TTCCTGCTCTTATTAACTTGTATTATGAATCAAATTAAGTTTTATGTATAAGGCATTTACTATTCCAGTGACTTAGCTAATGAAAACATT
TAAAAATATGTATTAATTTACTTGGCCTGCTACTAAAGTGCTTAACATAACTAAATGGATCTATAGTAACATGTCTAAATTTTTTAATGG
AAATAAGGGACTAACCATAATCCTTTTGAGTCAGCTTGGTGCTTACAATTATTTTGTTAGGAAATCTTGATGCTTTCTTCTTTCTCTTTA
AATTTTTGTAATCAAGCAACAGACTTGATCCAGCAGTGTCGAATTCCAAGCAAGTTATGATGATTCTTATTGTAGTTCAAGTACAGATGA
GTAAGTGGTGTGACTTCAGTTTATTATCTTCTTGGTGACCTACTTTAGTATGTGTTCTGTAGCGATTCATATTAGTTAAGGGACGTTTTC
AATATGCTTGAAATAAGAAATAGCATTTTACTCTAAATACAAGAAATGACTGTACACAAATGCTAATCAGTGATTTGGGGCCTTTTAATG
TCTTTAACAGCAATCTTTTATTTATTTATTTATTTATTTTTGAGACGGAGTCTTGCTGTGTCACCAGGCTGGAGCAGTGGCACGATCTCG
CCTCACTGCAACCTCCGCCTCCCAGGTTCAAGCTATTCTCCTGCCTCAGCCTCCCAAGTAACTGGGACTGCAGGCACATGCCACCACATC
CAGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCTTGTTGGCCAGGATGATCTCGATCTCTTGATCTCGTGATCTGCCCGCATT
GGCCTCCTGAAGTGCTGGGATTACAGGCATGAGCCACTGCGCCCGGCCCAAATCTTTTATTTTTTAACAGCCTTAGTTATTTATAATTCA
AATGCACTAAAATATCATCGCTGTCATGAACTTTGCTGTTTACAGGTTCTGTGTAATTCAGAATGCTTTGTACTTAGAAAATAATTTCTA
GGCTTATCTTGTTTTGCAGTTTTCATGTTTTGACAATTGCCCACCATTTACAATACTCAATTTTTGATTATGAAATGAATAGTAAAATTC
AAACATATCTAATAATAATTTGCCTTAGTTTGATTAATAAATTATATCAAAAAACTTGGGGATAGAAAGAGGCTTTTTTTTCCCCCTGTA
GTATTTTTAAAACTTTTTAGATGAGCTGGATGAAACCTTAGTACATTGGAGCTGGAGTTGTATTGAGTACAGCCCCAACTCTGAAGCCTT
ATATTCATGTCTTAAGTACCATTGATTGTTCTGTGAATTGTTGTTAGTTTCATATTTGACATTGTAGTAATCCACCTTGCATTTTAGTCT
TTGCAAAAAGGATATTGCTAGGTATATTCTTATTTCTGATTGAGTATTGAATTTACATTTTTCAGAATTTCATTCTTTGTCATTATAATC
CAAAAACAATGTCCACATCAGACTTGGAACTTCTCACTTCAAAAATGAAATACAGATTTAGCAGTGTTGTACATAATGATGTCCAAGCAT
TTTTCCACCTGTTTACTGAGTTTTCCAACCATTTACTATGTGTTGAGATTGGTGGGTTTTCTGGCTGTTTTTCTGAGGTGAATGACTTGT
TACAGAGCCTCAGTAAGAAATTTCAACTAAAATCACAAAAACATAAAGTCCAGGAAACCACCAGAAGATGGATTTTTAGTGTTTTTGAAA
TCTTGTATTTCCTTTTGATATCATTTACTCATTTTAATTTTACGACTGCCAACTTGTTACGGTATTAATTATATGTATGTGTTTATATGT
ATGCATATAATATATGTATATGTATATGAAGAATAAAGTTAAGATTTGGTCAAACTATATTTTCCCATTCAAGTACAAAAATGTTTTCAA

>In-frame_ENST00000372596_ENST00000307602_TCGA-HB-A5W3-01A_SCMH1_chr1_41578955_-_HOOK3_chr8_42761316_length(amino acids)=710AA_start in transcript=1096_stop in transcript=3228
METTCSLLAPKIQTFNVDAPCQTVEDLTNGVVMAQVLQKIDPAYFDENWLNRIKTEVGDNWRLKISNLKKILKGILDYNHEILGQQINDF
TLPDVNLIGEHSDAAELGRMLQLILGCAVNCEQKQEYIQAIMMMEESVQHVVMTAIQELMSKESPVSAGNDAYVDLDRQLKKTTEELNEA
LSAKEEIAQRCHELDMQVAALQEEKSSLLAENQVLMERLNQSDSIEDPNSPAGRRHLQLQTQLEQLQEETFRLEAAKDDYRIRCEELEKE
ISELRQQNDELTTLADEAQSLKDEIDVLRHSSDKVSKLEGQVESYKKKLEDLGDLRRQVKLLEEKNTMYMQNTVSLEEELRKANAARSQL
ETYKRQVVELQNRLSEESKKADKLDFEYKRLKEKVDSLQKEKDRLRTERDSLKETIEELRCVQAQEGQLTTQGLMPLGSQESSDSLAAEI
VTPEIREKLIRLQHENKMLKLNQEGSDNEKIALLQSLLDDANLRKNELETENRLVNQRLLEVQSQVEELQKSLQDQGSKAEDSVLLKKKL
EEHLEKLHEANNELQKKRAIIEDLEPRFNNSSLKIEELQEALRKKEEEMKQMEERYKKYLEKAKSVIRTLDPKQNQGAAPEIQALKNQLQ

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Fusion Gene PPI Analysis for SCMH1-HOOK3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SCMH1-HOOK3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SCMH1-HOOK3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneSCMH1C0004238Atrial Fibrillation2CTD_human
HgeneSCMH1C0235480Paroxysmal atrial fibrillation2CTD_human
HgeneSCMH1C2585653Persistent atrial fibrillation2CTD_human
HgeneSCMH1C3468561familial atrial fibrillation2CTD_human
TgeneHOOK3C0032460Polycystic Ovary Syndrome1CTD_human
TgeneHOOK3C1136382Sclerocystic Ovaries1CTD_human