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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:SCMH1-MACF1 (FusionGDB2 ID:79164)

Fusion Gene Summary for SCMH1-MACF1

Fusion gene summary

Fusion gene information	Fusion gene name: SCMH1-MACF1
	Fusion gene ID: 79164
		Hgene	Tgene
	Gene symbol	SCMH1	MACF1
	Gene ID	22955	23499
	Gene name	Scm polycomb group protein homolog 1	microtubule actin crosslinking factor 1
	Synonyms	Scml3	ABP620\|ACF7\|LIS9\|MACF\|OFC4
	Cytomap	1p34.2	1p34.3
	Type of gene	protein-coding	protein-coding
	Description	polycomb protein SCMH1sex comb on midleg homolog 1	microtubule-actin cross-linking factor 1620 kDa actin binding proteinactin cross-linking family protein 7macrophin 1 isoformtrabeculin-alpha
	Modification date	20200313	20200313
	UniProtAcc	.	Q9UPN3
	Ensembl transtripts involved in fusion gene	ENST00000456518, ENST00000397174, ENST00000402904, ENST00000361191, ENST00000397171, ENST00000361705, ENST00000326197, ENST00000372595, ENST00000337495, ENST00000372596, ENST00000372597, ENST00000472037,	ENST00000545844, ENST00000567887, ENST00000372915, ENST00000361689, ENST00000539005, ENST00000317713, ENST00000564288, ENST00000289893, ENST00000536367, ENST00000484793, ENST00000602421, ENST00000476350,
Fusion gene scores	* DoF score	18 X 14 X 11=2772	24 X 23 X 9=4968
	# samples	24	24
	** MAII score	log2(24/2772*10)=-3.52982094652869 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(24/4968*10)=-4.37155886261196 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: SCMH1 [Title/Abstract] AND MACF1 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	SCMH1(41608550)-MACF1(39945470), # samples:1
Anticipated loss of major functional domain due to fusion event.	SCMH1-MACF1 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF. SCMH1-MACF1 seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	MACF1	GO:0030334	regulation of cell migration	27693509
Tgene	MACF1	GO:0043001	Golgi to plasma membrane protein transport	15265687
Tgene	MACF1	GO:0045773	positive regulation of axon extension	22705394
Tgene	MACF1	GO:0051893	regulation of focal adhesion assembly	27693509

Fusion gene breakpoints across SCMH1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across MACF1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	PRAD	TCGA-CH-5788-01A	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+

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Fusion Gene ORF analysis for SCMH1-MACF1

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
In-frame	ENST00000456518	ENST00000545844	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
In-frame	ENST00000456518	ENST00000567887	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
In-frame	ENST00000456518	ENST00000372915	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
In-frame	ENST00000456518	ENST00000361689	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
In-frame	ENST00000456518	ENST00000539005	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
In-frame	ENST00000456518	ENST00000317713	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
In-frame	ENST00000456518	ENST00000564288	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
In-frame	ENST00000456518	ENST00000289893	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000456518	ENST00000536367	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000456518	ENST00000484793	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000456518	ENST00000602421	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000456518	ENST00000476350	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000397174	ENST00000545844	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000397174	ENST00000567887	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000397174	ENST00000372915	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000397174	ENST00000361689	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000397174	ENST00000539005	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000397174	ENST00000317713	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000397174	ENST00000564288	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000397174	ENST00000289893	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000397174	ENST00000536367	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000397174	ENST00000484793	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000397174	ENST00000602421	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000397174	ENST00000476350	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000402904	ENST00000545844	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000402904	ENST00000567887	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000402904	ENST00000372915	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000402904	ENST00000361689	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000402904	ENST00000539005	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000402904	ENST00000317713	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000402904	ENST00000564288	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000402904	ENST00000289893	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000402904	ENST00000536367	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000402904	ENST00000484793	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000402904	ENST00000602421	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000402904	ENST00000476350	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000361191	ENST00000545844	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000361191	ENST00000567887	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000361191	ENST00000372915	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000361191	ENST00000361689	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000361191	ENST00000539005	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000361191	ENST00000317713	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000361191	ENST00000564288	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000361191	ENST00000289893	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000361191	ENST00000536367	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000361191	ENST00000484793	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000361191	ENST00000602421	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000361191	ENST00000476350	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000397171	ENST00000545844	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000397171	ENST00000567887	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000397171	ENST00000372915	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000397171	ENST00000361689	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000397171	ENST00000539005	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000397171	ENST00000317713	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000397171	ENST00000564288	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000397171	ENST00000289893	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000397171	ENST00000536367	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000397171	ENST00000484793	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000397171	ENST00000602421	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000397171	ENST00000476350	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000361705	ENST00000545844	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000361705	ENST00000567887	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000361705	ENST00000372915	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000361705	ENST00000361689	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000361705	ENST00000539005	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000361705	ENST00000317713	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000361705	ENST00000564288	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000361705	ENST00000289893	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000361705	ENST00000536367	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000361705	ENST00000484793	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000361705	ENST00000602421	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000361705	ENST00000476350	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000326197	ENST00000545844	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000326197	ENST00000567887	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000326197	ENST00000372915	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000326197	ENST00000361689	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000326197	ENST00000539005	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000326197	ENST00000317713	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000326197	ENST00000564288	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000326197	ENST00000289893	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000326197	ENST00000536367	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000326197	ENST00000484793	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000326197	ENST00000602421	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000326197	ENST00000476350	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000372595	ENST00000545844	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000372595	ENST00000567887	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000372595	ENST00000372915	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000372595	ENST00000361689	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000372595	ENST00000539005	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000372595	ENST00000317713	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000372595	ENST00000564288	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000372595	ENST00000289893	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000372595	ENST00000536367	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000372595	ENST00000484793	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000372595	ENST00000602421	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000372595	ENST00000476350	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000337495	ENST00000545844	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000337495	ENST00000567887	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000337495	ENST00000372915	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000337495	ENST00000361689	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000337495	ENST00000539005	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000337495	ENST00000317713	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000337495	ENST00000564288	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000337495	ENST00000289893	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000337495	ENST00000536367	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000337495	ENST00000484793	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000337495	ENST00000602421	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000337495	ENST00000476350	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000372596	ENST00000545844	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000372596	ENST00000567887	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000372596	ENST00000372915	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000372596	ENST00000361689	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000372596	ENST00000539005	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000372596	ENST00000317713	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000372596	ENST00000564288	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000372596	ENST00000289893	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000372596	ENST00000536367	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000372596	ENST00000484793	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000372596	ENST00000602421	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000372596	ENST00000476350	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000372597	ENST00000545844	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000372597	ENST00000567887	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000372597	ENST00000372915	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000372597	ENST00000361689	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000372597	ENST00000539005	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000372597	ENST00000317713	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000372597	ENST00000564288	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
Frame-shift	ENST00000372597	ENST00000289893	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000372597	ENST00000536367	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000372597	ENST00000484793	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000372597	ENST00000602421	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
5CDS-intron	ENST00000372597	ENST00000476350	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
intron-3CDS	ENST00000472037	ENST00000545844	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
intron-3CDS	ENST00000472037	ENST00000567887	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
intron-3CDS	ENST00000472037	ENST00000372915	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
intron-3CDS	ENST00000472037	ENST00000361689	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
intron-3CDS	ENST00000472037	ENST00000539005	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
intron-3CDS	ENST00000472037	ENST00000317713	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
intron-3CDS	ENST00000472037	ENST00000564288	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
intron-3CDS	ENST00000472037	ENST00000289893	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
intron-intron	ENST00000472037	ENST00000536367	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
intron-intron	ENST00000472037	ENST00000484793	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
intron-intron	ENST00000472037	ENST00000602421	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+
intron-intron	ENST00000472037	ENST00000476350	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000456518	SCMH1	chr1	41608550	-	ENST00000545844	MACF1	chr1	39945470	+	2366	444	203	1042	279
ENST00000456518	SCMH1	chr1	41608550	-	ENST00000567887	MACF1	chr1	39945470	+	2537	444	203	1153	316
ENST00000456518	SCMH1	chr1	41608550	-	ENST00000372915	MACF1	chr1	39945470	+	2229	444	203	1042	279
ENST00000456518	SCMH1	chr1	41608550	-	ENST00000361689	MACF1	chr1	39945470	+	2236	444	203	1042	279
ENST00000456518	SCMH1	chr1	41608550	-	ENST00000539005	MACF1	chr1	39945470	+	2366	444	203	1042	279
ENST00000456518	SCMH1	chr1	41608550	-	ENST00000317713	MACF1	chr1	39945470	+	2366	444	203	1042	279
ENST00000456518	SCMH1	chr1	41608550	-	ENST00000564288	MACF1	chr1	39945470	+	2537	444	203	1153	316
ENST00000456518	SCMH1	chr1	41608550	-	ENST00000289893	MACF1	chr1	39945470	+	2236	444	203	1042	279

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000456518	ENST00000545844	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+	0.091779545	0.9082204
ENST00000456518	ENST00000567887	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+	0.040270213	0.95972973
ENST00000456518	ENST00000372915	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+	0.106491774	0.8935082
ENST00000456518	ENST00000361689	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+	0.10628174	0.8937183
ENST00000456518	ENST00000539005	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+	0.091779545	0.9082204
ENST00000456518	ENST00000317713	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+	0.091779545	0.9082204
ENST00000456518	ENST00000564288	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+	0.040270213	0.95972973
ENST00000456518	ENST00000289893	SCMH1	chr1	41608550	-	MACF1	chr1	39945470	+	0.10628174	0.8937183

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Fusion Genomic Features for SCMH1-MACF1

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
SCMH1	chr1	41608549	-	MACF1	chr1	39945469	+	0.001579087	0.99842095
SCMH1	chr1	41608549	-	MACF1	chr1	39945469	+	0.001579087	0.99842095

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SCMH1-MACF1

Go to
FGviewer for the breakpoints of chr1:41608550-chr1:39945470
.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	MACF1 Q9UPN3
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.	FUNCTION: [Isoform 2]: F-actin-binding protein which plays a role in cross-linking actin to other cytoskeletal proteins and also binds to microtubules (PubMed:15265687, PubMed:20937854). Plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex (PubMed:20937854). Acts as a positive regulator of Wnt receptor signaling pathway and is involved in the translocation of AXIN1 and its associated complex (composed of APC, CTNNB1 and GSK3B) from the cytoplasm to the cell membrane (By similarity). Has actin-regulated ATPase activity and is essential for controlling focal adhesions (FAs) assembly and dynamics (By similarity). Interaction with CAMSAP3 at the minus ends of non-centrosomal microtubules tethers microtubules minus-ends to actin filaments, regulating focal adhesion size and cell migration (PubMed:27693509). May play role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with GOLGA4 (PubMed:15265687). Plays a key role in wound healing and epidermal cell migration (By similarity). Required for efficient upward migration of bulge cells in response to wounding and this function is primarily rooted in its ability to coordinate microtubule dynamics and polarize hair follicle stem cells (By similarity). As a regulator of actin and microtubule arrangement and stabilization, it plays an essential role in neurite outgrowth, branching and spine formation during brain development (By similarity). {ECO:0000250\|UniProtKB:Q9QXZ0, ECO:0000269\|PubMed:15265687, ECO:0000269\|PubMed:20937854, ECO:0000269\|PubMed:27693509}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

SCMH1

chr1:41608550

chr1:39945470

ENST00000326197

28_126

127.33333333333333

661.0

Repeat

Note=MBT 1

Hgene

SCMH1

chr1:41608550

chr1:39945470

ENST00000337495

28_126

137.33333333333334

649.0

Repeat

Note=MBT 1

Hgene

SCMH1

chr1:41608550

chr1:39945470

ENST00000402904

28_126

127.33333333333333

661.0

Repeat

Note=MBT 1

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

7054_7065

5739.333333333333

5939.0

Calcium binding

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

7090_7101

5739.333333333333

5939.0

Calcium binding

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

7054_7065

5231.333333333333

5431.0

Calcium binding

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

7090_7101

5231.333333333333

5431.0

Calcium binding

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

7054_7065

5231.333333333333

5431.0

Calcium binding

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

7090_7101

5231.333333333333

5431.0

Calcium binding

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

7222_7351

5739.333333333333

5939.0

Compositional bias

Note=Ser-rich

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

7222_7351

5231.333333333333

5431.0

Compositional bias

Note=Ser-rich

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

7222_7351

7189.333333333333

7389.0

Compositional bias

Note=Ser-rich

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

7222_7351

5231.333333333333

5431.0

Compositional bias

Note=Ser-rich

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

7041_7076

5739.333333333333

5939.0

Domain

EF-hand 1

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

7077_7112

5739.333333333333

5939.0

Domain

EF-hand 2

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

7117_7189

5739.333333333333

5939.0

Domain

GAR

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

7041_7076

5231.333333333333

5431.0

Domain

EF-hand 1

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

7077_7112

5231.333333333333

5431.0

Domain

EF-hand 2

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

7117_7189

5231.333333333333

5431.0

Domain

GAR

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

7041_7076

5231.333333333333

5431.0

Domain

EF-hand 1

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

7077_7112

5231.333333333333

5431.0

Domain

EF-hand 2

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

7117_7189

5231.333333333333

5431.0

Domain

GAR

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

7117_7388

5739.333333333333

5939.0

Region

C-terminal tail

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

7313_7328

5739.333333333333

5939.0

Region

Note=4 X 4 AA tandem repeats of [GS]-S-R-[AR]

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

7117_7388

5231.333333333333

5431.0

Region

C-terminal tail

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

7313_7328

5231.333333333333

5431.0

Region

Note=4 X 4 AA tandem repeats of [GS]-S-R-[AR]

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

7313_7328

7189.333333333333

7389.0

Region

Note=4 X 4 AA tandem repeats of [GS]-S-R-[AR]

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

7117_7388

5231.333333333333

5431.0

Region

C-terminal tail

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

7313_7328

5231.333333333333

5431.0

Region

Note=4 X 4 AA tandem repeats of [GS]-S-R-[AR]

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

5783_5885

5739.333333333333

5939.0

Repeat

Note=Spectrin 9

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

5804_5828

5739.333333333333

5939.0

Repeat

Note=LRR 23

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

6005_6110

5739.333333333333

5939.0

Repeat

Note=Spectrin 10

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

6115_6219

5739.333333333333

5939.0

Repeat

Note=Spectrin 11

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

6225_6328

5739.333333333333

5939.0

Repeat

Note=Spectrin 12

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

6333_6439

5739.333333333333

5939.0

Repeat

Note=Spectrin 13

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

6443_6547

5739.333333333333

5939.0

Repeat

Note=Spectrin 14

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

6496_6519

5739.333333333333

5939.0

Repeat

Note=LRR 24

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

6552_6658

5739.333333333333

5939.0

Repeat

Note=Spectrin 15

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

6665_6766

5739.333333333333

5939.0

Repeat

Note=Spectrin 16

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

6771_6874

5739.333333333333

5939.0

Repeat

Note=Spectrin 17

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

5236_5341

5231.333333333333

5431.0

Repeat

Note=Spectrin 6

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

5281_5304

5231.333333333333

5431.0

Repeat

Note=LRR 21

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

5348_5450

5231.333333333333

5431.0

Repeat

Note=Spectrin 7

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

5455_5557

5231.333333333333

5431.0

Repeat

Note=Spectrin 8

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

5695_5719

5231.333333333333

5431.0

Repeat

Note=LRR 22

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

5783_5885

5231.333333333333

5431.0

Repeat

Note=Spectrin 9

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

5804_5828

5231.333333333333

5431.0

Repeat

Note=LRR 23

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

6005_6110

5231.333333333333

5431.0

Repeat

Note=Spectrin 10

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

6115_6219

5231.333333333333

5431.0

Repeat

Note=Spectrin 11

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

6225_6328

5231.333333333333

5431.0

Repeat

Note=Spectrin 12

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

6333_6439

5231.333333333333

5431.0

Repeat

Note=Spectrin 13

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

6443_6547

5231.333333333333

5431.0

Repeat

Note=Spectrin 14

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

6496_6519

5231.333333333333

5431.0

Repeat

Note=LRR 24

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

6552_6658

5231.333333333333

5431.0

Repeat

Note=Spectrin 15

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

6665_6766

5231.333333333333

5431.0

Repeat

Note=Spectrin 16

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

6771_6874

5231.333333333333

5431.0

Repeat

Note=Spectrin 17

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

5236_5341

5231.333333333333

5431.0

Repeat

Note=Spectrin 6

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

5281_5304

5231.333333333333

5431.0

Repeat

Note=LRR 21

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

5348_5450

5231.333333333333

5431.0

Repeat

Note=Spectrin 7

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

5455_5557

5231.333333333333

5431.0

Repeat

Note=Spectrin 8

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

5695_5719

5231.333333333333

5431.0

Repeat

Note=LRR 22

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

5783_5885

5231.333333333333

5431.0

Repeat

Note=Spectrin 9

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

5804_5828

5231.333333333333

5431.0

Repeat

Note=LRR 23

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

6005_6110

5231.333333333333

5431.0

Repeat

Note=Spectrin 10

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

6115_6219

5231.333333333333

5431.0

Repeat

Note=Spectrin 11

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

6225_6328

5231.333333333333

5431.0

Repeat

Note=Spectrin 12

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

6333_6439

5231.333333333333

5431.0

Repeat

Note=Spectrin 13

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

6443_6547

5231.333333333333

5431.0

Repeat

Note=Spectrin 14

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

6496_6519

5231.333333333333

5431.0

Repeat

Note=LRR 24

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

6552_6658

5231.333333333333

5431.0

Repeat

Note=Spectrin 15

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

6665_6766

5231.333333333333

5431.0

Repeat

Note=Spectrin 16

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

6771_6874

5231.333333333333

5431.0

Repeat

Note=Spectrin 17

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

SCMH1

chr1:41608550

chr1:39945470

ENST00000326197

593_658

127.33333333333333

661.0

Domain

SAM

Hgene

SCMH1

chr1:41608550

chr1:39945470

ENST00000337495

593_658

137.33333333333334

649.0

Domain

SAM

Hgene

SCMH1

chr1:41608550

chr1:39945470

ENST00000361191

593_658

66.33333333333333

578.0

Domain

SAM

Hgene

SCMH1

chr1:41608550

chr1:39945470

ENST00000361705

593_658

80.33333333333333

592.0

Domain

SAM

Hgene

SCMH1

chr1:41608550

chr1:39945470

ENST00000372595

593_658

66.33333333333333

600.0

Domain

SAM

Hgene

SCMH1

chr1:41608550

chr1:39945470

ENST00000372596

593_658

66.33333333333333

578.0

Domain

SAM

Hgene

SCMH1

chr1:41608550

chr1:39945470

ENST00000372597

593_658

80.33333333333333

592.0

Domain

SAM

Hgene

SCMH1

chr1:41608550

chr1:39945470

ENST00000397171

593_658

66.33333333333333

578.0

Domain

SAM

Hgene

SCMH1

chr1:41608550

chr1:39945470

ENST00000402904

593_658

127.33333333333333

661.0

Domain

SAM

Hgene

SCMH1

chr1:41608550

chr1:39945470

ENST00000456518

593_658

80.33333333333333

481.0

Domain

SAM

Hgene

SCMH1

chr1:41608550

chr1:39945470

ENST00000326197

134_235

127.33333333333333

661.0

Repeat

Note=MBT 2

Hgene

SCMH1

chr1:41608550

chr1:39945470

ENST00000337495

134_235

137.33333333333334

649.0

Repeat

Note=MBT 2

Hgene

SCMH1

chr1:41608550

chr1:39945470

ENST00000361191

134_235

66.33333333333333

578.0

Repeat

Note=MBT 2

Hgene

SCMH1

chr1:41608550

chr1:39945470

ENST00000361191

28_126

66.33333333333333

578.0

Repeat

Note=MBT 1

Hgene

SCMH1

chr1:41608550

chr1:39945470

ENST00000361705

134_235

80.33333333333333

592.0

Repeat

Note=MBT 2

Hgene

SCMH1

chr1:41608550

chr1:39945470

ENST00000361705

28_126

80.33333333333333

592.0

Repeat

Note=MBT 1

Hgene

SCMH1

chr1:41608550

chr1:39945470

ENST00000372595

134_235

66.33333333333333

600.0

Repeat

Note=MBT 2

Hgene

SCMH1

chr1:41608550

chr1:39945470

ENST00000372595

28_126

66.33333333333333

600.0

Repeat

Note=MBT 1

Hgene

SCMH1

chr1:41608550

chr1:39945470

ENST00000372596

134_235

66.33333333333333

578.0

Repeat

Note=MBT 2

Hgene

SCMH1

chr1:41608550

chr1:39945470

ENST00000372596

28_126

66.33333333333333

578.0

Repeat

Note=MBT 1

Hgene

SCMH1

chr1:41608550

chr1:39945470

ENST00000372597

134_235

80.33333333333333

592.0

Repeat

Note=MBT 2

Hgene

SCMH1

chr1:41608550

chr1:39945470

ENST00000372597

28_126

80.33333333333333

592.0

Repeat

Note=MBT 1

Hgene

SCMH1

chr1:41608550

chr1:39945470

ENST00000397171

134_235

66.33333333333333

578.0

Repeat

Note=MBT 2

Hgene

SCMH1

chr1:41608550

chr1:39945470

ENST00000397171

28_126

66.33333333333333

578.0

Repeat

Note=MBT 1

Hgene

SCMH1

chr1:41608550

chr1:39945470

ENST00000402904

134_235

127.33333333333333

661.0

Repeat

Note=MBT 2

Hgene

SCMH1

chr1:41608550

chr1:39945470

ENST00000456518

134_235

80.33333333333333

481.0

Repeat

Note=MBT 2

Hgene

SCMH1

chr1:41608550

chr1:39945470

ENST00000456518

28_126

80.33333333333333

481.0

Repeat

Note=MBT 1

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

7054_7065

7189.333333333333

7389.0

Calcium binding

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

7090_7101

7189.333333333333

7389.0

Calcium binding

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

1122_1127

5739.333333333333

5939.0

Compositional bias

Note=Poly-Ser

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

1414_1417

5739.333333333333

5939.0

Compositional bias

Note=Poly-Glu

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

1986_1989

5739.333333333333

5939.0

Compositional bias

Note=Poly-Leu

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

698_703

5739.333333333333

5939.0

Compositional bias

Note=Poly-Glu

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

1122_1127

5231.333333333333

5431.0

Compositional bias

Note=Poly-Ser

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

1414_1417

5231.333333333333

5431.0

Compositional bias

Note=Poly-Glu

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

1986_1989

5231.333333333333

5431.0

Compositional bias

Note=Poly-Leu

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

698_703

5231.333333333333

5431.0

Compositional bias

Note=Poly-Glu

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

1122_1127

7189.333333333333

7389.0

Compositional bias

Note=Poly-Ser

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

1414_1417

7189.333333333333

7389.0

Compositional bias

Note=Poly-Glu

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

1986_1989

7189.333333333333

7389.0

Compositional bias

Note=Poly-Leu

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

698_703

7189.333333333333

7389.0

Compositional bias

Note=Poly-Glu

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

1122_1127

5231.333333333333

5431.0

Compositional bias

Note=Poly-Ser

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

1414_1417

5231.333333333333

5431.0

Compositional bias

Note=Poly-Glu

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

1986_1989

5231.333333333333

5431.0

Compositional bias

Note=Poly-Leu

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

698_703

5231.333333333333

5431.0

Compositional bias

Note=Poly-Glu

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

194_298

5739.333333333333

5939.0

Domain

Calponin-homology (CH) 2

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

78_181

5739.333333333333

5939.0

Domain

Calponin-homology (CH) 1

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

868_925

5739.333333333333

5939.0

Domain

SH3

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

194_298

5231.333333333333

5431.0

Domain

Calponin-homology (CH) 2

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

78_181

5231.333333333333

5431.0

Domain

Calponin-homology (CH) 1

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

868_925

5231.333333333333

5431.0

Domain

SH3

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

194_298

7189.333333333333

7389.0

Domain

Calponin-homology (CH) 2

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

7041_7076

7189.333333333333

7389.0

Domain

EF-hand 1

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

7077_7112

7189.333333333333

7389.0

Domain

EF-hand 2

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

7117_7189

7189.333333333333

7389.0

Domain

GAR

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

78_181

7189.333333333333

7389.0

Domain

Calponin-homology (CH) 1

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

868_925

7189.333333333333

7389.0

Domain

SH3

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

194_298

5231.333333333333

5431.0

Domain

Calponin-homology (CH) 2

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

78_181

5231.333333333333

5431.0

Domain

Calponin-homology (CH) 1

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

868_925

5231.333333333333

5431.0

Domain

SH3

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

1_295

5739.333333333333

5939.0

Region

Note=Actin-binding

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

1_295

5231.333333333333

5431.0

Region

Note=Actin-binding

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

1_295

7189.333333333333

7389.0

Region

Note=Actin-binding

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

7117_7388

7189.333333333333

7389.0

Region

C-terminal tail

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

1_295

5231.333333333333

5431.0

Region

Note=Actin-binding

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

1050_1073

5739.333333333333

5939.0

Repeat

Note=LRR 5

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

1128_1154

5739.333333333333

5939.0

Repeat

Note=LRR 6

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

1187_1210

5739.333333333333

5939.0

Repeat

Note=LRR 7

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

1257_1282

5739.333333333333

5939.0

Repeat

Note=LRR 8

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

148_171

5739.333333333333

5939.0

Repeat

Note=LRR 1

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

1577_1621

5739.333333333333

5939.0

Repeat

Note=Plectin 1

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

1654_1696

5739.333333333333

5939.0

Repeat

Note=Plectin 2

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

1769_1809

5739.333333333333

5939.0

Repeat

Note=Plectin 3

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

1811_1848

5739.333333333333

5939.0

Repeat

Note=Plectin 4

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

1855_1886

5739.333333333333

5939.0

Repeat

Note=Plectin 5

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

2290_2332

5739.333333333333

5939.0

Repeat

Note=Plectin 6

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

2367_2410

5739.333333333333

5939.0

Repeat

Note=Plectin 7

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

240_264

5739.333333333333

5939.0

Repeat

Note=LRR 2

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

2411_2437

5739.333333333333

5939.0

Repeat

Note=Plectin 8

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

2501_2543

5739.333333333333

5939.0

Repeat

Note=Plectin 9

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

2581_2612

5739.333333333333

5939.0

Repeat

Note=Plectin 10

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

2686_2730

5739.333333333333

5939.0

Repeat

Note=Plectin 11

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

3239_3262

5739.333333333333

5939.0

Repeat

Note=LRR 9

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

3264_3283

5739.333333333333

5939.0

Repeat

Note=LRR 10

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

3646_3669

5739.333333333333

5939.0

Repeat

Note=LRR 11

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

3696_3720

5739.333333333333

5939.0

Repeat

Note=LRR 12

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

377_399

5739.333333333333

5939.0

Repeat

Note=LRR 3

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

3883_3957

5739.333333333333

5939.0

Repeat

Note=Spectrin 1

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

3936_3958

5739.333333333333

5939.0

Repeat

Note=LRR 13

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

4000_4108

5739.333333333333

5939.0

Repeat

Note=Spectrin 2

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

4125_4150

5739.333333333333

5939.0

Repeat

Note=LRR 14

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

4261_4287

5739.333333333333

5939.0

Repeat

Note=LRR 15

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

441_464

5739.333333333333

5939.0

Repeat

Note=LRR 4

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

4466_4574

5739.333333333333

5939.0

Repeat

Note=Spectrin 3

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

4511_4534

5739.333333333333

5939.0

Repeat

Note=LRR 16

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

4601_4624

5739.333333333333

5939.0

Repeat

Note=LRR 17

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

4769_4792

5739.333333333333

5939.0

Repeat

Note=LRR 18

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

4800_4904

5739.333333333333

5939.0

Repeat

Note=Spectrin 4

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

4909_5012

5739.333333333333

5939.0

Repeat

Note=Spectrin 5

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

5051_5076

5739.333333333333

5939.0

Repeat

Note=LRR 19

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

5172_5194

5739.333333333333

5939.0

Repeat

Note=LRR 20

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

5236_5341

5739.333333333333

5939.0

Repeat

Note=Spectrin 6

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

5281_5304

5739.333333333333

5939.0

Repeat

Note=LRR 21

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

5348_5450

5739.333333333333

5939.0

Repeat

Note=Spectrin 7

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

5455_5557

5739.333333333333

5939.0

Repeat

Note=Spectrin 8

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000289893

5695_5719

5739.333333333333

5939.0

Repeat

Note=LRR 22

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

1050_1073

5231.333333333333

5431.0

Repeat

Note=LRR 5

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

1128_1154

5231.333333333333

5431.0

Repeat

Note=LRR 6

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

1187_1210

5231.333333333333

5431.0

Repeat

Note=LRR 7

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

1257_1282

5231.333333333333

5431.0

Repeat

Note=LRR 8

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

148_171

5231.333333333333

5431.0

Repeat

Note=LRR 1

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

1577_1621

5231.333333333333

5431.0

Repeat

Note=Plectin 1

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

1654_1696

5231.333333333333

5431.0

Repeat

Note=Plectin 2

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

1769_1809

5231.333333333333

5431.0

Repeat

Note=Plectin 3

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

1811_1848

5231.333333333333

5431.0

Repeat

Note=Plectin 4

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

1855_1886

5231.333333333333

5431.0

Repeat

Note=Plectin 5

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

2290_2332

5231.333333333333

5431.0

Repeat

Note=Plectin 6

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

2367_2410

5231.333333333333

5431.0

Repeat

Note=Plectin 7

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

240_264

5231.333333333333

5431.0

Repeat

Note=LRR 2

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

2411_2437

5231.333333333333

5431.0

Repeat

Note=Plectin 8

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

2501_2543

5231.333333333333

5431.0

Repeat

Note=Plectin 9

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

2581_2612

5231.333333333333

5431.0

Repeat

Note=Plectin 10

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

2686_2730

5231.333333333333

5431.0

Repeat

Note=Plectin 11

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

3239_3262

5231.333333333333

5431.0

Repeat

Note=LRR 9

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

3264_3283

5231.333333333333

5431.0

Repeat

Note=LRR 10

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

3646_3669

5231.333333333333

5431.0

Repeat

Note=LRR 11

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

3696_3720

5231.333333333333

5431.0

Repeat

Note=LRR 12

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

377_399

5231.333333333333

5431.0

Repeat

Note=LRR 3

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

3883_3957

5231.333333333333

5431.0

Repeat

Note=Spectrin 1

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

3936_3958

5231.333333333333

5431.0

Repeat

Note=LRR 13

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

4000_4108

5231.333333333333

5431.0

Repeat

Note=Spectrin 2

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

4125_4150

5231.333333333333

5431.0

Repeat

Note=LRR 14

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

4261_4287

5231.333333333333

5431.0

Repeat

Note=LRR 15

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

441_464

5231.333333333333

5431.0

Repeat

Note=LRR 4

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

4466_4574

5231.333333333333

5431.0

Repeat

Note=Spectrin 3

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

4511_4534

5231.333333333333

5431.0

Repeat

Note=LRR 16

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

4601_4624

5231.333333333333

5431.0

Repeat

Note=LRR 17

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

4769_4792

5231.333333333333

5431.0

Repeat

Note=LRR 18

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

4800_4904

5231.333333333333

5431.0

Repeat

Note=Spectrin 4

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

4909_5012

5231.333333333333

5431.0

Repeat

Note=Spectrin 5

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

5051_5076

5231.333333333333

5431.0

Repeat

Note=LRR 19

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000361689

5172_5194

5231.333333333333

5431.0

Repeat

Note=LRR 20

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

1050_1073

7189.333333333333

7389.0

Repeat

Note=LRR 5

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

1128_1154

7189.333333333333

7389.0

Repeat

Note=LRR 6

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

1187_1210

7189.333333333333

7389.0

Repeat

Note=LRR 7

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

1257_1282

7189.333333333333

7389.0

Repeat

Note=LRR 8

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

148_171

7189.333333333333

7389.0

Repeat

Note=LRR 1

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

1577_1621

7189.333333333333

7389.0

Repeat

Note=Plectin 1

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

1654_1696

7189.333333333333

7389.0

Repeat

Note=Plectin 2

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

1769_1809

7189.333333333333

7389.0

Repeat

Note=Plectin 3

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

1811_1848

7189.333333333333

7389.0

Repeat

Note=Plectin 4

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

1855_1886

7189.333333333333

7389.0

Repeat

Note=Plectin 5

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

2290_2332

7189.333333333333

7389.0

Repeat

Note=Plectin 6

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

2367_2410

7189.333333333333

7389.0

Repeat

Note=Plectin 7

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

240_264

7189.333333333333

7389.0

Repeat

Note=LRR 2

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

2411_2437

7189.333333333333

7389.0

Repeat

Note=Plectin 8

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

2501_2543

7189.333333333333

7389.0

Repeat

Note=Plectin 9

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

2581_2612

7189.333333333333

7389.0

Repeat

Note=Plectin 10

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

2686_2730

7189.333333333333

7389.0

Repeat

Note=Plectin 11

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

3239_3262

7189.333333333333

7389.0

Repeat

Note=LRR 9

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

3264_3283

7189.333333333333

7389.0

Repeat

Note=LRR 10

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

3646_3669

7189.333333333333

7389.0

Repeat

Note=LRR 11

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

3696_3720

7189.333333333333

7389.0

Repeat

Note=LRR 12

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

377_399

7189.333333333333

7389.0

Repeat

Note=LRR 3

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

3883_3957

7189.333333333333

7389.0

Repeat

Note=Spectrin 1

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

3936_3958

7189.333333333333

7389.0

Repeat

Note=LRR 13

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

4000_4108

7189.333333333333

7389.0

Repeat

Note=Spectrin 2

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

4125_4150

7189.333333333333

7389.0

Repeat

Note=LRR 14

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

4261_4287

7189.333333333333

7389.0

Repeat

Note=LRR 15

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

441_464

7189.333333333333

7389.0

Repeat

Note=LRR 4

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

4466_4574

7189.333333333333

7389.0

Repeat

Note=Spectrin 3

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

4511_4534

7189.333333333333

7389.0

Repeat

Note=LRR 16

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

4601_4624

7189.333333333333

7389.0

Repeat

Note=LRR 17

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

4769_4792

7189.333333333333

7389.0

Repeat

Note=LRR 18

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

4800_4904

7189.333333333333

7389.0

Repeat

Note=Spectrin 4

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

4909_5012

7189.333333333333

7389.0

Repeat

Note=Spectrin 5

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

5051_5076

7189.333333333333

7389.0

Repeat

Note=LRR 19

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

5172_5194

7189.333333333333

7389.0

Repeat

Note=LRR 20

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

5236_5341

7189.333333333333

7389.0

Repeat

Note=Spectrin 6

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

5281_5304

7189.333333333333

7389.0

Repeat

Note=LRR 21

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

5348_5450

7189.333333333333

7389.0

Repeat

Note=Spectrin 7

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

5455_5557

7189.333333333333

7389.0

Repeat

Note=Spectrin 8

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

5695_5719

7189.333333333333

7389.0

Repeat

Note=LRR 22

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

5783_5885

7189.333333333333

7389.0

Repeat

Note=Spectrin 9

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

5804_5828

7189.333333333333

7389.0

Repeat

Note=LRR 23

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

6005_6110

7189.333333333333

7389.0

Repeat

Note=Spectrin 10

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

6115_6219

7189.333333333333

7389.0

Repeat

Note=Spectrin 11

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

6225_6328

7189.333333333333

7389.0

Repeat

Note=Spectrin 12

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

6333_6439

7189.333333333333

7389.0

Repeat

Note=Spectrin 13

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

6443_6547

7189.333333333333

7389.0

Repeat

Note=Spectrin 14

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

6496_6519

7189.333333333333

7389.0

Repeat

Note=LRR 24

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

6552_6658

7189.333333333333

7389.0

Repeat

Note=Spectrin 15

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

6665_6766

7189.333333333333

7389.0

Repeat

Note=Spectrin 16

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000372915

6771_6874

7189.333333333333

7389.0

Repeat

Note=Spectrin 17

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

1050_1073

5231.333333333333

5431.0

Repeat

Note=LRR 5

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

1128_1154

5231.333333333333

5431.0

Repeat

Note=LRR 6

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

1187_1210

5231.333333333333

5431.0

Repeat

Note=LRR 7

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

1257_1282

5231.333333333333

5431.0

Repeat

Note=LRR 8

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

148_171

5231.333333333333

5431.0

Repeat

Note=LRR 1

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

1577_1621

5231.333333333333

5431.0

Repeat

Note=Plectin 1

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

1654_1696

5231.333333333333

5431.0

Repeat

Note=Plectin 2

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

1769_1809

5231.333333333333

5431.0

Repeat

Note=Plectin 3

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

1811_1848

5231.333333333333

5431.0

Repeat

Note=Plectin 4

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

1855_1886

5231.333333333333

5431.0

Repeat

Note=Plectin 5

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

2290_2332

5231.333333333333

5431.0

Repeat

Note=Plectin 6

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

2367_2410

5231.333333333333

5431.0

Repeat

Note=Plectin 7

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

240_264

5231.333333333333

5431.0

Repeat

Note=LRR 2

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

2411_2437

5231.333333333333

5431.0

Repeat

Note=Plectin 8

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

2501_2543

5231.333333333333

5431.0

Repeat

Note=Plectin 9

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

2581_2612

5231.333333333333

5431.0

Repeat

Note=Plectin 10

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

2686_2730

5231.333333333333

5431.0

Repeat

Note=Plectin 11

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

3239_3262

5231.333333333333

5431.0

Repeat

Note=LRR 9

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

3264_3283

5231.333333333333

5431.0

Repeat

Note=LRR 10

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

3646_3669

5231.333333333333

5431.0

Repeat

Note=LRR 11

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

3696_3720

5231.333333333333

5431.0

Repeat

Note=LRR 12

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

377_399

5231.333333333333

5431.0

Repeat

Note=LRR 3

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

3883_3957

5231.333333333333

5431.0

Repeat

Note=Spectrin 1

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

3936_3958

5231.333333333333

5431.0

Repeat

Note=LRR 13

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

4000_4108

5231.333333333333

5431.0

Repeat

Note=Spectrin 2

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

4125_4150

5231.333333333333

5431.0

Repeat

Note=LRR 14

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

4261_4287

5231.333333333333

5431.0

Repeat

Note=LRR 15

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

441_464

5231.333333333333

5431.0

Repeat

Note=LRR 4

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

4466_4574

5231.333333333333

5431.0

Repeat

Note=Spectrin 3

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

4511_4534

5231.333333333333

5431.0

Repeat

Note=LRR 16

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

4601_4624

5231.333333333333

5431.0

Repeat

Note=LRR 17

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

4769_4792

5231.333333333333

5431.0

Repeat

Note=LRR 18

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

4800_4904

5231.333333333333

5431.0

Repeat

Note=Spectrin 4

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

4909_5012

5231.333333333333

5431.0

Repeat

Note=Spectrin 5

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

5051_5076

5231.333333333333

5431.0

Repeat

Note=LRR 19

Tgene

MACF1

chr1:41608550

chr1:39945470

ENST00000545844

5172_5194

5231.333333333333

5431.0

Repeat

Note=LRR 20

Top

Fusion Gene Sequence for SCMH1-MACF1

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>In-frame_ENST00000456518_ENST00000545844_TCGA-CH-5788-01A_SCMH1_chr1_41608550_-_MACF1_chr1_39945470_length(transcript)=2366nt_BP=444nt
GGTTGTAAAGAAGATTACATGAGCTAATGGATGTGAAAACATCTTAAAAACTCTCAAATACTTTTCAACTTTGGAGGATTATTATGATTT
TCATTCTGTTCAGCGGCTATACTCAGACTTTACTCTAAAAGTCAAATCTTCTGACATTCTTTGAAGTGAAGCATTCTATGAATGTGAGCT
GAAGAAATGAATGAAATGAAATAATGCAGTCCTACACACCTCCAAGCAACGAGTTCAAGATCAGTATGAAATTGGAAGCACAGGACCCCA
GGAACACCACATCCACCTGTATTGCCACAGTAGTTGGACTGACAGGTGCCCGCCTTCGCCTGCGCCTTGATGGGAGCGACAACAAAAATG
ACTTCTGGCGGCTGGTTGACTCAGCTGAAATCCAGCCTATTGGGAACTGTGAAAAGAATGGGGGTATGCTACAGCCACCTCTTGCACGAG
GTAGAACTAACATTGAACTTAGAGAGAAATTCATCCTACCAGAGGGAGCATCCCAGGGAATGACCCCCTTCCGCTCACGGGGTCGAAGGT
CCAAACCATCTTCCCGGGCAGCTTCCCCTACTCGTTCCAGCTCCAGTGCTAGTCAGAGTAACCACAGCTGTACATCCATGCCATCTTCTC
CAGCCACCCCAGCCAGTGGAACCAAGGTTATCCCATCATCAGGTAGCAAGTTGAAACGACCAACACCAACTTTTCATTCTAGTCGGACAT
CCCTTGCTGGTGATACCAGCAATAGTTCTTCCCCGGCCTCCACAGGTGCCAAAACTAATCGGGCAGACCCTAAAAAGTCTGCCAGTCGCC
CTGGGAGTCGGGCTGGGAGTCGAGCCGGGAGTCGAGCCAGCAGCCGGCGAGGAAGTGACGCTTCTGACTTTGACCTCTTAGAGACGCAGT
CTGCTTGTTCCGACACTTCAGAAAGCAGCGCTGCAGGGGGCCAAGGCAACTCCAGGAGAGGGCTAAACAAACCTTCCAAAATCCCAACCA
TGTCTAAGAAGACCACCACTGCCTCCCCCAGGACTCCAGGTCCCAAGCGATAACACTGTCTAAGCACCCCCAAGCCACTATCCACTTTGA
ATCCTGCTCCATACATTGGGTGTATATTTATTCTGAACGGGAGAAGTTATATTGTTAAAAGTGTAAAAGAATAATTGTGTTATGAAGCTG
CCTTATTTTTTTTCTTTTTGTAAGTTACTATTTTCATGTGAATATTTATGTAGATAAAATTTGCCTCCTGGTAACCCTGTAATGGATGGG
GCCCAGAAATGAAATATTTGAGAAAAACAAGTGAAAAGGTCAAGATACAAATGTGTATTAAAAAAAAAAAAGCCTATTAATAGGGTTTCT
GCGCGGTGCAGGGTTGTAAACCTGCTTTATCTTTTAGGATTATTCCTAAATGCATCTTCTTTATAAACTTGACTTGCTATCTCAGCAAGA
TAAATTATATTAAAAAAATAAGAATCCTGCAGTGTTTAAGGAACTCTTTTTTTGTAAATCACGGACACCTCAATTAGCAAGAACTGAGGG
GAGGGCTTTTTCCATTGTTTAATGTTTTGTGATTTTTAGCTAAAGAGAGGGAACCTCATCTAAGTAACATTTGCACATGATACAGCAAAA
GGAGTTCATTGCAATACTGTCTTTGGATATTGTTTCAGTACTGGGTGTTTAAAGGACAAATAGCTGCTAGAATTCAGGGGTAAATGTAAG
TGTTCAGAAAACGTCAGAACATTTGGGGTTTTAAACTGATTTGTTGCTCCCTATCCAGCCTAGACACCAGTAACTCTTGTGTTCACCAGG
ACCCAGACCCTTGGCAAGGGATAGGCTCGTTGGTGACATTGTGAATTTCAGATTTGTTTTATCCACTTTTTTTGCTATTTATTTAAATGG
TCGATCAACTTCCCACAAACTGAGGAATGAATTCCACGAGCCTGTTCTGAAAATGTGGACGTAAGACAAACACGTGCTCGTCCTTTAATG
GAGTTCACCAGCACACTTGTTAACCAGTCCTGTTTGCTTTCGTCTTTTTTTGTGCGTAATAAAGTCAACTGACCAAGTGACCATGAAAAG
GGGCTGTCTGGGGCTCCTGTTTTTTAGCTGCTGTTCTTCAGCTCCGACCATGTTGCTGTGTGATTATCTCAATTGGTTTTAATTGAGGCA
GAAACTGAAGCTCTACCAATGAACTGTTTAGAAACAAGACACACTTTTGTATTAAAATTGCTTGCAGTAACAAATATTTTGTATTTCCTG
ATTTTCTTTTCAACTATTACCTTATCTATAAATGTTACCCTGGGGTATAATCATGTTGTAGGTACTTAAATGCATTCCGCAAATCAAAAT

>In-frame_ENST00000456518_ENST00000545844_TCGA-CH-5788-01A_SCMH1_chr1_41608550_-_MACF1_chr1_39945470_length(amino acids)=279AA_start in transcript=203_stop in transcript=1042
MQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLARGRTNIELR
EKFILPEGASQGMTPFRSRGRRSKPSSRAASPTRSSSSASQSNHSCTSMPSSPATPASGTKVIPSSGSKLKRPTPTFHSSRTSLAGDTSN
SSSPASTGAKTNRADPKKSASRPGSRAGSRAGSRASSRRGSDASDFDLLETQSACSDTSESSAAGGQGNSRRGLNKPSKIPTMSKKTTTA

--------------------------------------------------------------
>In-frame_ENST00000456518_ENST00000567887_TCGA-CH-5788-01A_SCMH1_chr1_41608550_-_MACF1_chr1_39945470_length(transcript)=2537nt_BP=444nt
GGTTGTAAAGAAGATTACATGAGCTAATGGATGTGAAAACATCTTAAAAACTCTCAAATACTTTTCAACTTTGGAGGATTATTATGATTT
TCATTCTGTTCAGCGGCTATACTCAGACTTTACTCTAAAAGTCAAATCTTCTGACATTCTTTGAAGTGAAGCATTCTATGAATGTGAGCT
GAAGAAATGAATGAAATGAAATAATGCAGTCCTACACACCTCCAAGCAACGAGTTCAAGATCAGTATGAAATTGGAAGCACAGGACCCCA
GGAACACCACATCCACCTGTATTGCCACAGTAGTTGGACTGACAGGTGCCCGCCTTCGCCTGCGCCTTGATGGGAGCGACAACAAAAATG
ACTTCTGGCGGCTGGTTGACTCAGCTGAAATCCAGCCTATTGGGAACTGTGAAAAGAATGGGGGTATGCTACAGCCACCTCTTGCACGAG
GTAGAACTAACATTGAACTTAGAGAGAAATTCATCCTACCAGAGGGAGCATCCCAGGGAATGACCCCCTTCCGCTCACGGGGTCGAAGGT
CCAAACCATCTTCCCGGGCAGCTTCCCCTACTCGTTCCAGCTCCAGTGCTAGTCAGAGTAACCACAGCTGTACATCCATGCCATCTTCTC
CAGCCACCCCAGCCAGTGGAACCAAGACTTCACTTCAGTTCTCTCGCTGTTATGACAAACCCTGGTTGGTAAACAGTAAAGCTGGCACCC
CTATCAGGGACAGCCATTCTCCTGACCTCCAGCTGCCCACCCCCGAGGTTATCCCATCATCAGGTAGCAAGTTGAAACGACCAACACCAA
CTTTTCATTCTAGTCGGACATCCCTTGCTGGTGATACCAGCAATAGTTCTTCCCCGGCCTCCACAGGTGCCAAAACTAATCGGGCAGACC
CTAAAAAGTCTGCCAGTCGCCCTGGGAGTCGGGCTGGGAGTCGAGCCGGGAGTCGAGCCAGCAGCCGGCGAGGAAGTGACGCTTCTGACT
TTGACCTCTTAGAGACGCAGTCTGCTTGTTCCGACACTTCAGAAAGCAGCGCTGCAGGGGGCCAAGGCAACTCCAGGAGAGGGCTAAACA
AACCTTCCAAAATCCCAACCATGTCTAAGAAGACCACCACTGCCTCCCCCAGGACTCCAGGTCCCAAGCGATAACACTGTCTAAGCACCC
CCAAGCCACTATCCACTTTGAATCCTGCTCCATACATTGGGTGTATATTTATTCTGAACGGGAGAAGTTATATTGTTAAAAGTGTAAAAG
AATAATTGTGTTATGAAGCTGCCTTATTTTTTTTCTTTTTGTAAGTTACTATTTTCATGTGAATATTTATGTAGATAAAATTTGCCTCCT
GGTAACCCTGTAATGGATGGGGCCCAGAAATGAAATATTTGAGAAAAACAAGTGAAAAGGTCAAGATACAAATGTGTATTAAAAAAAAAA
AAGCCTATTAATAGGGTTTCTGCGCGGTGCAGGGTTGTAAACCTGCTTTATCTTTTAGGATTATTCCTAAATGCATCTTCTTTATAAACT
TGACTTGCTATCTCAGCAAGATAAATTATATTAAAAAAATAAGAATCCTGCAGTGTTTAAGGAACTCTTTTTTTGTAAATCACGGACACC
TCAATTAGCAAGAACTGAGGGGAGGGCTTTTTCCATTGTTTAATGTTTTGTGATTTTTAGCTAAAGAGAGGGAACCTCATCTAAGTAACA
TTTGCACATGATACAGCAAAAGGAGTTCATTGCAATACTGTCTTTGGATATTGTTTCAGTACTGGGTGTTTAAAGGACAAATAGCTGCTA
GAATTCAGGGGTAAATGTAAGTGTTCAGAAAACGTCAGAACATTTGGGGTTTTAAACTGATTTGTTGCTCCCTATCCAGCCTAGACACCA
GTAACTCTTGTGTTCACCAGGACCCAGACCCTTGGCAAGGGATAGGCTCGTTGGTGACATTGTGAATTTCAGATTTGTTTTATCCACTTT
TTTTGCTATTTATTTAAATGGTCGATCAACTTCCCACAAACTGAGGAATGAATTCCACGAGCCTGTTCTGAAAATGTGGACGTAAGACAA
ACACGTGCTCGTCCTTTAATGGAGTTCACCAGCACACTTGTTAACCAGTCCTGTTTGCTTTCGTCTTTTTTTGTGCGTAATAAAGTCAAC
TGACCAAGTGACCATGAAAAGGGGCTGTCTGGGGCTCCTGTTTTTTAGCTGCTGTTCTTCAGCTCCGACCATGTTGCTGTGTGATTATCT
CAATTGGTTTTAATTGAGGCAGAAACTGAAGCTCTACCAATGAACTGTTTAGAAACAAGACACACTTTTGTATTAAAATTGCTTGCAGTA
ACAAATATTTTGTATTTCCTGATTTTCTTTTCAACTATTACCTTATCTATAAATGTTACCCTGGGGTATAATCATGTTGTAGGTACTTAA
ATGCATTCCGCAAATCAAAATATCTTGATGGATAAATTATAGAGCTTAATAGATCTTGTTTTATTTCATCCTTGTTAATTTTGTTTAATA

>In-frame_ENST00000456518_ENST00000567887_TCGA-CH-5788-01A_SCMH1_chr1_41608550_-_MACF1_chr1_39945470_length(amino acids)=316AA_start in transcript=203_stop in transcript=1153
MQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLARGRTNIELR
EKFILPEGASQGMTPFRSRGRRSKPSSRAASPTRSSSSASQSNHSCTSMPSSPATPASGTKTSLQFSRCYDKPWLVNSKAGTPIRDSHSP
DLQLPTPEVIPSSGSKLKRPTPTFHSSRTSLAGDTSNSSSPASTGAKTNRADPKKSASRPGSRAGSRAGSRASSRRGSDASDFDLLETQS

--------------------------------------------------------------
>In-frame_ENST00000456518_ENST00000372915_TCGA-CH-5788-01A_SCMH1_chr1_41608550_-_MACF1_chr1_39945470_length(transcript)=2229nt_BP=444nt
GGTTGTAAAGAAGATTACATGAGCTAATGGATGTGAAAACATCTTAAAAACTCTCAAATACTTTTCAACTTTGGAGGATTATTATGATTT
TCATTCTGTTCAGCGGCTATACTCAGACTTTACTCTAAAAGTCAAATCTTCTGACATTCTTTGAAGTGAAGCATTCTATGAATGTGAGCT
GAAGAAATGAATGAAATGAAATAATGCAGTCCTACACACCTCCAAGCAACGAGTTCAAGATCAGTATGAAATTGGAAGCACAGGACCCCA
GGAACACCACATCCACCTGTATTGCCACAGTAGTTGGACTGACAGGTGCCCGCCTTCGCCTGCGCCTTGATGGGAGCGACAACAAAAATG
ACTTCTGGCGGCTGGTTGACTCAGCTGAAATCCAGCCTATTGGGAACTGTGAAAAGAATGGGGGTATGCTACAGCCACCTCTTGCACGAG
GTAGAACTAACATTGAACTTAGAGAGAAATTCATCCTACCAGAGGGAGCATCCCAGGGAATGACCCCCTTCCGCTCACGGGGTCGAAGGT
CCAAACCATCTTCCCGGGCAGCTTCCCCTACTCGTTCCAGCTCCAGTGCTAGTCAGAGTAACCACAGCTGTACATCCATGCCATCTTCTC
CAGCCACCCCAGCCAGTGGAACCAAGGTTATCCCATCATCAGGTAGCAAGTTGAAACGACCAACACCAACTTTTCATTCTAGTCGGACAT
CCCTTGCTGGTGATACCAGCAATAGTTCTTCCCCGGCCTCCACAGGTGCCAAAACTAATCGGGCAGACCCTAAAAAGTCTGCCAGTCGCC
CTGGGAGTCGGGCTGGGAGTCGAGCCGGGAGTCGAGCCAGCAGCCGGCGAGGAAGTGACGCTTCTGACTTTGACCTCTTAGAGACGCAGT
CTGCTTGTTCCGACACTTCAGAAAGCAGCGCTGCAGGGGGCCAAGGCAACTCCAGGAGAGGGCTAAACAAACCTTCCAAAATCCCAACCA
TGTCTAAGAAGACCACCACTGCCTCCCCCAGGACTCCAGGTCCCAAGCGATAACACTGTCTAAGCACCCCCAAGCCACTATCCACTTTGA
ATCCTGCTCCATACATTGGGTGTATATTTATTCTGAACGGGAGAAGTTATATTGTTAAAAGTGTAAAAGAATAATTGTGTTATGAAGCTG
CCTTATTTTTTTTCTTTTTGTAAGTTACTATTTTCATGTGAATATTTATGTAGATAAAATTTGCCTCCTGGTAACCCTGTAATGGATGGG
GCCCAGAAATGAAATATTTGAGAAAAACAAGTGAAAAGGTCAAGATACAAATGTGTATTAAAAAAAAAAAAGCCTATTAATAGGGTTTCT
GCGCGGTGCAGGGTTGTAAACCTGCTTTATCTTTTAGGATTATTCCTAAATGCATCTTCTTTATAAACTTGACTTGCTATCTCAGCAAGA
TAAATTATATTAAAAAAATAAGAATCCTGCAGTGTTTAAGGAACTCTTTTTTTGTAAATCACGGACACCTCAATTAGCAAGAACTGAGGG
GAGGGCTTTTTCCATTGTTTAATGTTTTGTGATTTTTAGCTAAAGAGAGGGAACCTCATCTAAGTAACATTTGCACATGATACAGCAAAA
GGAGTTCATTGCAATACTGTCTTTGGATATTGTTTCAGTACTGGGTGTTTAAAGGACAAATAGCTGCTAGAATTCAGGGGTAAATGTAAG
TGTTCAGAAAACGTCAGAACATTTGGGGTTTTAAACTGATTTGTTGCTCCCTATCCAGCCTAGACACCAGTAACTCTTGTGTTCACCAGG
ACCCAGACCCTTGGCAAGGGATAGGCTCGTTGGTGACATTGTGAATTTCAGATTTGTTTTATCCACTTTTTTTGCTATTTATTTAAATGG
TCGATCAACTTCCCACAAACTGAGGAATGAATTCCACGAGCCTGTTCTGAAAATGTGGACGTAAGACAAACACGTGCTCGTCCTTTAATG
GAGTTCACCAGCACACTTGTTAACCAGTCCTGTTTGCTTTCGTCTTTTTTTGTGCGTAATAAAGTCAACTGACCAAGTGACCATGAAAAG
GGGCTGTCTGGGGCTCCTGTTTTTTAGCTGCTGTTCTTCAGCTCCGACCATGTTGCTGTGTGATTATCTCAATTGGTTTTAATTGAGGCA

>In-frame_ENST00000456518_ENST00000372915_TCGA-CH-5788-01A_SCMH1_chr1_41608550_-_MACF1_chr1_39945470_length(amino acids)=279AA_start in transcript=203_stop in transcript=1042
MQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLARGRTNIELR
EKFILPEGASQGMTPFRSRGRRSKPSSRAASPTRSSSSASQSNHSCTSMPSSPATPASGTKVIPSSGSKLKRPTPTFHSSRTSLAGDTSN
SSSPASTGAKTNRADPKKSASRPGSRAGSRAGSRASSRRGSDASDFDLLETQSACSDTSESSAAGGQGNSRRGLNKPSKIPTMSKKTTTA

--------------------------------------------------------------
>In-frame_ENST00000456518_ENST00000361689_TCGA-CH-5788-01A_SCMH1_chr1_41608550_-_MACF1_chr1_39945470_length(transcript)=2236nt_BP=444nt
GGTTGTAAAGAAGATTACATGAGCTAATGGATGTGAAAACATCTTAAAAACTCTCAAATACTTTTCAACTTTGGAGGATTATTATGATTT
TCATTCTGTTCAGCGGCTATACTCAGACTTTACTCTAAAAGTCAAATCTTCTGACATTCTTTGAAGTGAAGCATTCTATGAATGTGAGCT
GAAGAAATGAATGAAATGAAATAATGCAGTCCTACACACCTCCAAGCAACGAGTTCAAGATCAGTATGAAATTGGAAGCACAGGACCCCA
GGAACACCACATCCACCTGTATTGCCACAGTAGTTGGACTGACAGGTGCCCGCCTTCGCCTGCGCCTTGATGGGAGCGACAACAAAAATG
ACTTCTGGCGGCTGGTTGACTCAGCTGAAATCCAGCCTATTGGGAACTGTGAAAAGAATGGGGGTATGCTACAGCCACCTCTTGCACGAG
GTAGAACTAACATTGAACTTAGAGAGAAATTCATCCTACCAGAGGGAGCATCCCAGGGAATGACCCCCTTCCGCTCACGGGGTCGAAGGT
CCAAACCATCTTCCCGGGCAGCTTCCCCTACTCGTTCCAGCTCCAGTGCTAGTCAGAGTAACCACAGCTGTACATCCATGCCATCTTCTC
CAGCCACCCCAGCCAGTGGAACCAAGGTTATCCCATCATCAGGTAGCAAGTTGAAACGACCAACACCAACTTTTCATTCTAGTCGGACAT
CCCTTGCTGGTGATACCAGCAATAGTTCTTCCCCGGCCTCCACAGGTGCCAAAACTAATCGGGCAGACCCTAAAAAGTCTGCCAGTCGCC
CTGGGAGTCGGGCTGGGAGTCGAGCCGGGAGTCGAGCCAGCAGCCGGCGAGGAAGTGACGCTTCTGACTTTGACCTCTTAGAGACGCAGT
CTGCTTGTTCCGACACTTCAGAAAGCAGCGCTGCAGGGGGCCAAGGCAACTCCAGGAGAGGGCTAAACAAACCTTCCAAAATCCCAACCA
TGTCTAAGAAGACCACCACTGCCTCCCCCAGGACTCCAGGTCCCAAGCGATAACACTGTCTAAGCACCCCCAAGCCACTATCCACTTTGA
ATCCTGCTCCATACATTGGGTGTATATTTATTCTGAACGGGAGAAGTTATATTGTTAAAAGTGTAAAAGAATAATTGTGTTATGAAGCTG
CCTTATTTTTTTTCTTTTTGTAAGTTACTATTTTCATGTGAATATTTATGTAGATAAAATTTGCCTCCTGGTAACCCTGTAATGGATGGG
GCCCAGAAATGAAATATTTGAGAAAAACAAGTGAAAAGGTCAAGATACAAATGTGTATTAAAAAAAAAAAAGCCTATTAATAGGGTTTCT
GCGCGGTGCAGGGTTGTAAACCTGCTTTATCTTTTAGGATTATTCCTAAATGCATCTTCTTTATAAACTTGACTTGCTATCTCAGCAAGA
TAAATTATATTAAAAAAATAAGAATCCTGCAGTGTTTAAGGAACTCTTTTTTTGTAAATCACGGACACCTCAATTAGCAAGAACTGAGGG
GAGGGCTTTTTCCATTGTTTAATGTTTTGTGATTTTTAGCTAAAGAGAGGGAACCTCATCTAAGTAACATTTGCACATGATACAGCAAAA
GGAGTTCATTGCAATACTGTCTTTGGATATTGTTTCAGTACTGGGTGTTTAAAGGACAAATAGCTGCTAGAATTCAGGGGTAAATGTAAG
TGTTCAGAAAACGTCAGAACATTTGGGGTTTTAAACTGATTTGTTGCTCCCTATCCAGCCTAGACACCAGTAACTCTTGTGTTCACCAGG
ACCCAGACCCTTGGCAAGGGATAGGCTCGTTGGTGACATTGTGAATTTCAGATTTGTTTTATCCACTTTTTTTGCTATTTATTTAAATGG
TCGATCAACTTCCCACAAACTGAGGAATGAATTCCACGAGCCTGTTCTGAAAATGTGGACGTAAGACAAACACGTGCTCGTCCTTTAATG
GAGTTCACCAGCACACTTGTTAACCAGTCCTGTTTGCTTTCGTCTTTTTTTGTGCGTAATAAAGTCAACTGACCAAGTGACCATGAAAAG
GGGCTGTCTGGGGCTCCTGTTTTTTAGCTGCTGTTCTTCAGCTCCGACCATGTTGCTGTGTGATTATCTCAATTGGTTTTAATTGAGGCA

>In-frame_ENST00000456518_ENST00000361689_TCGA-CH-5788-01A_SCMH1_chr1_41608550_-_MACF1_chr1_39945470_length(amino acids)=279AA_start in transcript=203_stop in transcript=1042
MQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLARGRTNIELR
EKFILPEGASQGMTPFRSRGRRSKPSSRAASPTRSSSSASQSNHSCTSMPSSPATPASGTKVIPSSGSKLKRPTPTFHSSRTSLAGDTSN
SSSPASTGAKTNRADPKKSASRPGSRAGSRAGSRASSRRGSDASDFDLLETQSACSDTSESSAAGGQGNSRRGLNKPSKIPTMSKKTTTA

--------------------------------------------------------------
>In-frame_ENST00000456518_ENST00000539005_TCGA-CH-5788-01A_SCMH1_chr1_41608550_-_MACF1_chr1_39945470_length(transcript)=2366nt_BP=444nt
GGTTGTAAAGAAGATTACATGAGCTAATGGATGTGAAAACATCTTAAAAACTCTCAAATACTTTTCAACTTTGGAGGATTATTATGATTT
TCATTCTGTTCAGCGGCTATACTCAGACTTTACTCTAAAAGTCAAATCTTCTGACATTCTTTGAAGTGAAGCATTCTATGAATGTGAGCT
GAAGAAATGAATGAAATGAAATAATGCAGTCCTACACACCTCCAAGCAACGAGTTCAAGATCAGTATGAAATTGGAAGCACAGGACCCCA
GGAACACCACATCCACCTGTATTGCCACAGTAGTTGGACTGACAGGTGCCCGCCTTCGCCTGCGCCTTGATGGGAGCGACAACAAAAATG
ACTTCTGGCGGCTGGTTGACTCAGCTGAAATCCAGCCTATTGGGAACTGTGAAAAGAATGGGGGTATGCTACAGCCACCTCTTGCACGAG
GTAGAACTAACATTGAACTTAGAGAGAAATTCATCCTACCAGAGGGAGCATCCCAGGGAATGACCCCCTTCCGCTCACGGGGTCGAAGGT
CCAAACCATCTTCCCGGGCAGCTTCCCCTACTCGTTCCAGCTCCAGTGCTAGTCAGAGTAACCACAGCTGTACATCCATGCCATCTTCTC
CAGCCACCCCAGCCAGTGGAACCAAGGTTATCCCATCATCAGGTAGCAAGTTGAAACGACCAACACCAACTTTTCATTCTAGTCGGACAT
CCCTTGCTGGTGATACCAGCAATAGTTCTTCCCCGGCCTCCACAGGTGCCAAAACTAATCGGGCAGACCCTAAAAAGTCTGCCAGTCGCC
CTGGGAGTCGGGCTGGGAGTCGAGCCGGGAGTCGAGCCAGCAGCCGGCGAGGAAGTGACGCTTCTGACTTTGACCTCTTAGAGACGCAGT
CTGCTTGTTCCGACACTTCAGAAAGCAGCGCTGCAGGGGGCCAAGGCAACTCCAGGAGAGGGCTAAACAAACCTTCCAAAATCCCAACCA
TGTCTAAGAAGACCACCACTGCCTCCCCCAGGACTCCAGGTCCCAAGCGATAACACTGTCTAAGCACCCCCAAGCCACTATCCACTTTGA
ATCCTGCTCCATACATTGGGTGTATATTTATTCTGAACGGGAGAAGTTATATTGTTAAAAGTGTAAAAGAATAATTGTGTTATGAAGCTG
CCTTATTTTTTTTCTTTTTGTAAGTTACTATTTTCATGTGAATATTTATGTAGATAAAATTTGCCTCCTGGTAACCCTGTAATGGATGGG
GCCCAGAAATGAAATATTTGAGAAAAACAAGTGAAAAGGTCAAGATACAAATGTGTATTAAAAAAAAAAAAGCCTATTAATAGGGTTTCT
GCGCGGTGCAGGGTTGTAAACCTGCTTTATCTTTTAGGATTATTCCTAAATGCATCTTCTTTATAAACTTGACTTGCTATCTCAGCAAGA
TAAATTATATTAAAAAAATAAGAATCCTGCAGTGTTTAAGGAACTCTTTTTTTGTAAATCACGGACACCTCAATTAGCAAGAACTGAGGG
GAGGGCTTTTTCCATTGTTTAATGTTTTGTGATTTTTAGCTAAAGAGAGGGAACCTCATCTAAGTAACATTTGCACATGATACAGCAAAA
GGAGTTCATTGCAATACTGTCTTTGGATATTGTTTCAGTACTGGGTGTTTAAAGGACAAATAGCTGCTAGAATTCAGGGGTAAATGTAAG
TGTTCAGAAAACGTCAGAACATTTGGGGTTTTAAACTGATTTGTTGCTCCCTATCCAGCCTAGACACCAGTAACTCTTGTGTTCACCAGG
ACCCAGACCCTTGGCAAGGGATAGGCTCGTTGGTGACATTGTGAATTTCAGATTTGTTTTATCCACTTTTTTTGCTATTTATTTAAATGG
TCGATCAACTTCCCACAAACTGAGGAATGAATTCCACGAGCCTGTTCTGAAAATGTGGACGTAAGACAAACACGTGCTCGTCCTTTAATG
GAGTTCACCAGCACACTTGTTAACCAGTCCTGTTTGCTTTCGTCTTTTTTTGTGCGTAATAAAGTCAACTGACCAAGTGACCATGAAAAG
GGGCTGTCTGGGGCTCCTGTTTTTTAGCTGCTGTTCTTCAGCTCCGACCATGTTGCTGTGTGATTATCTCAATTGGTTTTAATTGAGGCA
GAAACTGAAGCTCTACCAATGAACTGTTTAGAAACAAGACACACTTTTGTATTAAAATTGCTTGCAGTAACAAATATTTTGTATTTCCTG
ATTTTCTTTTCAACTATTACCTTATCTATAAATGTTACCCTGGGGTATAATCATGTTGTAGGTACTTAAATGCATTCCGCAAATCAAAAT

>In-frame_ENST00000456518_ENST00000539005_TCGA-CH-5788-01A_SCMH1_chr1_41608550_-_MACF1_chr1_39945470_length(amino acids)=279AA_start in transcript=203_stop in transcript=1042
MQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLARGRTNIELR
EKFILPEGASQGMTPFRSRGRRSKPSSRAASPTRSSSSASQSNHSCTSMPSSPATPASGTKVIPSSGSKLKRPTPTFHSSRTSLAGDTSN
SSSPASTGAKTNRADPKKSASRPGSRAGSRAGSRASSRRGSDASDFDLLETQSACSDTSESSAAGGQGNSRRGLNKPSKIPTMSKKTTTA

--------------------------------------------------------------
>In-frame_ENST00000456518_ENST00000317713_TCGA-CH-5788-01A_SCMH1_chr1_41608550_-_MACF1_chr1_39945470_length(transcript)=2366nt_BP=444nt
GGTTGTAAAGAAGATTACATGAGCTAATGGATGTGAAAACATCTTAAAAACTCTCAAATACTTTTCAACTTTGGAGGATTATTATGATTT
TCATTCTGTTCAGCGGCTATACTCAGACTTTACTCTAAAAGTCAAATCTTCTGACATTCTTTGAAGTGAAGCATTCTATGAATGTGAGCT
GAAGAAATGAATGAAATGAAATAATGCAGTCCTACACACCTCCAAGCAACGAGTTCAAGATCAGTATGAAATTGGAAGCACAGGACCCCA
GGAACACCACATCCACCTGTATTGCCACAGTAGTTGGACTGACAGGTGCCCGCCTTCGCCTGCGCCTTGATGGGAGCGACAACAAAAATG
ACTTCTGGCGGCTGGTTGACTCAGCTGAAATCCAGCCTATTGGGAACTGTGAAAAGAATGGGGGTATGCTACAGCCACCTCTTGCACGAG
GTAGAACTAACATTGAACTTAGAGAGAAATTCATCCTACCAGAGGGAGCATCCCAGGGAATGACCCCCTTCCGCTCACGGGGTCGAAGGT
CCAAACCATCTTCCCGGGCAGCTTCCCCTACTCGTTCCAGCTCCAGTGCTAGTCAGAGTAACCACAGCTGTACATCCATGCCATCTTCTC
CAGCCACCCCAGCCAGTGGAACCAAGGTTATCCCATCATCAGGTAGCAAGTTGAAACGACCAACACCAACTTTTCATTCTAGTCGGACAT
CCCTTGCTGGTGATACCAGCAATAGTTCTTCCCCGGCCTCCACAGGTGCCAAAACTAATCGGGCAGACCCTAAAAAGTCTGCCAGTCGCC
CTGGGAGTCGGGCTGGGAGTCGAGCCGGGAGTCGAGCCAGCAGCCGGCGAGGAAGTGACGCTTCTGACTTTGACCTCTTAGAGACGCAGT
CTGCTTGTTCCGACACTTCAGAAAGCAGCGCTGCAGGGGGCCAAGGCAACTCCAGGAGAGGGCTAAACAAACCTTCCAAAATCCCAACCA
TGTCTAAGAAGACCACCACTGCCTCCCCCAGGACTCCAGGTCCCAAGCGATAACACTGTCTAAGCACCCCCAAGCCACTATCCACTTTGA
ATCCTGCTCCATACATTGGGTGTATATTTATTCTGAACGGGAGAAGTTATATTGTTAAAAGTGTAAAAGAATAATTGTGTTATGAAGCTG
CCTTATTTTTTTTCTTTTTGTAAGTTACTATTTTCATGTGAATATTTATGTAGATAAAATTTGCCTCCTGGTAACCCTGTAATGGATGGG
GCCCAGAAATGAAATATTTGAGAAAAACAAGTGAAAAGGTCAAGATACAAATGTGTATTAAAAAAAAAAAAGCCTATTAATAGGGTTTCT
GCGCGGTGCAGGGTTGTAAACCTGCTTTATCTTTTAGGATTATTCCTAAATGCATCTTCTTTATAAACTTGACTTGCTATCTCAGCAAGA
TAAATTATATTAAAAAAATAAGAATCCTGCAGTGTTTAAGGAACTCTTTTTTTGTAAATCACGGACACCTCAATTAGCAAGAACTGAGGG
GAGGGCTTTTTCCATTGTTTAATGTTTTGTGATTTTTAGCTAAAGAGAGGGAACCTCATCTAAGTAACATTTGCACATGATACAGCAAAA
GGAGTTCATTGCAATACTGTCTTTGGATATTGTTTCAGTACTGGGTGTTTAAAGGACAAATAGCTGCTAGAATTCAGGGGTAAATGTAAG
TGTTCAGAAAACGTCAGAACATTTGGGGTTTTAAACTGATTTGTTGCTCCCTATCCAGCCTAGACACCAGTAACTCTTGTGTTCACCAGG
ACCCAGACCCTTGGCAAGGGATAGGCTCGTTGGTGACATTGTGAATTTCAGATTTGTTTTATCCACTTTTTTTGCTATTTATTTAAATGG
TCGATCAACTTCCCACAAACTGAGGAATGAATTCCACGAGCCTGTTCTGAAAATGTGGACGTAAGACAAACACGTGCTCGTCCTTTAATG
GAGTTCACCAGCACACTTGTTAACCAGTCCTGTTTGCTTTCGTCTTTTTTTGTGCGTAATAAAGTCAACTGACCAAGTGACCATGAAAAG
GGGCTGTCTGGGGCTCCTGTTTTTTAGCTGCTGTTCTTCAGCTCCGACCATGTTGCTGTGTGATTATCTCAATTGGTTTTAATTGAGGCA
GAAACTGAAGCTCTACCAATGAACTGTTTAGAAACAAGACACACTTTTGTATTAAAATTGCTTGCAGTAACAAATATTTTGTATTTCCTG
ATTTTCTTTTCAACTATTACCTTATCTATAAATGTTACCCTGGGGTATAATCATGTTGTAGGTACTTAAATGCATTCCGCAAATCAAAAT

>In-frame_ENST00000456518_ENST00000317713_TCGA-CH-5788-01A_SCMH1_chr1_41608550_-_MACF1_chr1_39945470_length(amino acids)=279AA_start in transcript=203_stop in transcript=1042
MQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLARGRTNIELR
EKFILPEGASQGMTPFRSRGRRSKPSSRAASPTRSSSSASQSNHSCTSMPSSPATPASGTKVIPSSGSKLKRPTPTFHSSRTSLAGDTSN
SSSPASTGAKTNRADPKKSASRPGSRAGSRAGSRASSRRGSDASDFDLLETQSACSDTSESSAAGGQGNSRRGLNKPSKIPTMSKKTTTA

--------------------------------------------------------------
>In-frame_ENST00000456518_ENST00000564288_TCGA-CH-5788-01A_SCMH1_chr1_41608550_-_MACF1_chr1_39945470_length(transcript)=2537nt_BP=444nt
GGTTGTAAAGAAGATTACATGAGCTAATGGATGTGAAAACATCTTAAAAACTCTCAAATACTTTTCAACTTTGGAGGATTATTATGATTT
TCATTCTGTTCAGCGGCTATACTCAGACTTTACTCTAAAAGTCAAATCTTCTGACATTCTTTGAAGTGAAGCATTCTATGAATGTGAGCT
GAAGAAATGAATGAAATGAAATAATGCAGTCCTACACACCTCCAAGCAACGAGTTCAAGATCAGTATGAAATTGGAAGCACAGGACCCCA
GGAACACCACATCCACCTGTATTGCCACAGTAGTTGGACTGACAGGTGCCCGCCTTCGCCTGCGCCTTGATGGGAGCGACAACAAAAATG
ACTTCTGGCGGCTGGTTGACTCAGCTGAAATCCAGCCTATTGGGAACTGTGAAAAGAATGGGGGTATGCTACAGCCACCTCTTGCACGAG
GTAGAACTAACATTGAACTTAGAGAGAAATTCATCCTACCAGAGGGAGCATCCCAGGGAATGACCCCCTTCCGCTCACGGGGTCGAAGGT
CCAAACCATCTTCCCGGGCAGCTTCCCCTACTCGTTCCAGCTCCAGTGCTAGTCAGAGTAACCACAGCTGTACATCCATGCCATCTTCTC
CAGCCACCCCAGCCAGTGGAACCAAGACTTCACTTCAGTTCTCTCGCTGTTATGACAAACCCTGGTTGGTAAACAGTAAAGCTGGCACCC
CTATCAGGGACAGCCATTCTCCTGACCTCCAGCTGCCCACCCCCGAGGTTATCCCATCATCAGGTAGCAAGTTGAAACGACCAACACCAA
CTTTTCATTCTAGTCGGACATCCCTTGCTGGTGATACCAGCAATAGTTCTTCCCCGGCCTCCACAGGTGCCAAAACTAATCGGGCAGACC
CTAAAAAGTCTGCCAGTCGCCCTGGGAGTCGGGCTGGGAGTCGAGCCGGGAGTCGAGCCAGCAGCCGGCGAGGAAGTGACGCTTCTGACT
TTGACCTCTTAGAGACGCAGTCTGCTTGTTCCGACACTTCAGAAAGCAGCGCTGCAGGGGGCCAAGGCAACTCCAGGAGAGGGCTAAACA
AACCTTCCAAAATCCCAACCATGTCTAAGAAGACCACCACTGCCTCCCCCAGGACTCCAGGTCCCAAGCGATAACACTGTCTAAGCACCC
CCAAGCCACTATCCACTTTGAATCCTGCTCCATACATTGGGTGTATATTTATTCTGAACGGGAGAAGTTATATTGTTAAAAGTGTAAAAG
AATAATTGTGTTATGAAGCTGCCTTATTTTTTTTCTTTTTGTAAGTTACTATTTTCATGTGAATATTTATGTAGATAAAATTTGCCTCCT
GGTAACCCTGTAATGGATGGGGCCCAGAAATGAAATATTTGAGAAAAACAAGTGAAAAGGTCAAGATACAAATGTGTATTAAAAAAAAAA
AAGCCTATTAATAGGGTTTCTGCGCGGTGCAGGGTTGTAAACCTGCTTTATCTTTTAGGATTATTCCTAAATGCATCTTCTTTATAAACT
TGACTTGCTATCTCAGCAAGATAAATTATATTAAAAAAATAAGAATCCTGCAGTGTTTAAGGAACTCTTTTTTTGTAAATCACGGACACC
TCAATTAGCAAGAACTGAGGGGAGGGCTTTTTCCATTGTTTAATGTTTTGTGATTTTTAGCTAAAGAGAGGGAACCTCATCTAAGTAACA
TTTGCACATGATACAGCAAAAGGAGTTCATTGCAATACTGTCTTTGGATATTGTTTCAGTACTGGGTGTTTAAAGGACAAATAGCTGCTA
GAATTCAGGGGTAAATGTAAGTGTTCAGAAAACGTCAGAACATTTGGGGTTTTAAACTGATTTGTTGCTCCCTATCCAGCCTAGACACCA
GTAACTCTTGTGTTCACCAGGACCCAGACCCTTGGCAAGGGATAGGCTCGTTGGTGACATTGTGAATTTCAGATTTGTTTTATCCACTTT
TTTTGCTATTTATTTAAATGGTCGATCAACTTCCCACAAACTGAGGAATGAATTCCACGAGCCTGTTCTGAAAATGTGGACGTAAGACAA
ACACGTGCTCGTCCTTTAATGGAGTTCACCAGCACACTTGTTAACCAGTCCTGTTTGCTTTCGTCTTTTTTTGTGCGTAATAAAGTCAAC
TGACCAAGTGACCATGAAAAGGGGCTGTCTGGGGCTCCTGTTTTTTAGCTGCTGTTCTTCAGCTCCGACCATGTTGCTGTGTGATTATCT
CAATTGGTTTTAATTGAGGCAGAAACTGAAGCTCTACCAATGAACTGTTTAGAAACAAGACACACTTTTGTATTAAAATTGCTTGCAGTA
ACAAATATTTTGTATTTCCTGATTTTCTTTTCAACTATTACCTTATCTATAAATGTTACCCTGGGGTATAATCATGTTGTAGGTACTTAA
ATGCATTCCGCAAATCAAAATATCTTGATGGATAAATTATAGAGCTTAATAGATCTTGTTTTATTTCATCCTTGTTAATTTTGTTTAATA

>In-frame_ENST00000456518_ENST00000564288_TCGA-CH-5788-01A_SCMH1_chr1_41608550_-_MACF1_chr1_39945470_length(amino acids)=316AA_start in transcript=203_stop in transcript=1153
MQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLARGRTNIELR
EKFILPEGASQGMTPFRSRGRRSKPSSRAASPTRSSSSASQSNHSCTSMPSSPATPASGTKTSLQFSRCYDKPWLVNSKAGTPIRDSHSP
DLQLPTPEVIPSSGSKLKRPTPTFHSSRTSLAGDTSNSSSPASTGAKTNRADPKKSASRPGSRAGSRAGSRASSRRGSDASDFDLLETQS

--------------------------------------------------------------
>In-frame_ENST00000456518_ENST00000289893_TCGA-CH-5788-01A_SCMH1_chr1_41608550_-_MACF1_chr1_39945470_length(transcript)=2236nt_BP=444nt
GGTTGTAAAGAAGATTACATGAGCTAATGGATGTGAAAACATCTTAAAAACTCTCAAATACTTTTCAACTTTGGAGGATTATTATGATTT
TCATTCTGTTCAGCGGCTATACTCAGACTTTACTCTAAAAGTCAAATCTTCTGACATTCTTTGAAGTGAAGCATTCTATGAATGTGAGCT
GAAGAAATGAATGAAATGAAATAATGCAGTCCTACACACCTCCAAGCAACGAGTTCAAGATCAGTATGAAATTGGAAGCACAGGACCCCA
GGAACACCACATCCACCTGTATTGCCACAGTAGTTGGACTGACAGGTGCCCGCCTTCGCCTGCGCCTTGATGGGAGCGACAACAAAAATG
ACTTCTGGCGGCTGGTTGACTCAGCTGAAATCCAGCCTATTGGGAACTGTGAAAAGAATGGGGGTATGCTACAGCCACCTCTTGCACGAG
GTAGAACTAACATTGAACTTAGAGAGAAATTCATCCTACCAGAGGGAGCATCCCAGGGAATGACCCCCTTCCGCTCACGGGGTCGAAGGT
CCAAACCATCTTCCCGGGCAGCTTCCCCTACTCGTTCCAGCTCCAGTGCTAGTCAGAGTAACCACAGCTGTACATCCATGCCATCTTCTC
CAGCCACCCCAGCCAGTGGAACCAAGGTTATCCCATCATCAGGTAGCAAGTTGAAACGACCAACACCAACTTTTCATTCTAGTCGGACAT
CCCTTGCTGGTGATACCAGCAATAGTTCTTCCCCGGCCTCCACAGGTGCCAAAACTAATCGGGCAGACCCTAAAAAGTCTGCCAGTCGCC
CTGGGAGTCGGGCTGGGAGTCGAGCCGGGAGTCGAGCCAGCAGCCGGCGAGGAAGTGACGCTTCTGACTTTGACCTCTTAGAGACGCAGT
CTGCTTGTTCCGACACTTCAGAAAGCAGCGCTGCAGGGGGCCAAGGCAACTCCAGGAGAGGGCTAAACAAACCTTCCAAAATCCCAACCA
TGTCTAAGAAGACCACCACTGCCTCCCCCAGGACTCCAGGTCCCAAGCGATAACACTGTCTAAGCACCCCCAAGCCACTATCCACTTTGA
ATCCTGCTCCATACATTGGGTGTATATTTATTCTGAACGGGAGAAGTTATATTGTTAAAAGTGTAAAAGAATAATTGTGTTATGAAGCTG
CCTTATTTTTTTTCTTTTTGTAAGTTACTATTTTCATGTGAATATTTATGTAGATAAAATTTGCCTCCTGGTAACCCTGTAATGGATGGG
GCCCAGAAATGAAATATTTGAGAAAAACAAGTGAAAAGGTCAAGATACAAATGTGTATTAAAAAAAAAAAAGCCTATTAATAGGGTTTCT
GCGCGGTGCAGGGTTGTAAACCTGCTTTATCTTTTAGGATTATTCCTAAATGCATCTTCTTTATAAACTTGACTTGCTATCTCAGCAAGA
TAAATTATATTAAAAAAATAAGAATCCTGCAGTGTTTAAGGAACTCTTTTTTTGTAAATCACGGACACCTCAATTAGCAAGAACTGAGGG
GAGGGCTTTTTCCATTGTTTAATGTTTTGTGATTTTTAGCTAAAGAGAGGGAACCTCATCTAAGTAACATTTGCACATGATACAGCAAAA
GGAGTTCATTGCAATACTGTCTTTGGATATTGTTTCAGTACTGGGTGTTTAAAGGACAAATAGCTGCTAGAATTCAGGGGTAAATGTAAG
TGTTCAGAAAACGTCAGAACATTTGGGGTTTTAAACTGATTTGTTGCTCCCTATCCAGCCTAGACACCAGTAACTCTTGTGTTCACCAGG
ACCCAGACCCTTGGCAAGGGATAGGCTCGTTGGTGACATTGTGAATTTCAGATTTGTTTTATCCACTTTTTTTGCTATTTATTTAAATGG
TCGATCAACTTCCCACAAACTGAGGAATGAATTCCACGAGCCTGTTCTGAAAATGTGGACGTAAGACAAACACGTGCTCGTCCTTTAATG
GAGTTCACCAGCACACTTGTTAACCAGTCCTGTTTGCTTTCGTCTTTTTTTGTGCGTAATAAAGTCAACTGACCAAGTGACCATGAAAAG
GGGCTGTCTGGGGCTCCTGTTTTTTAGCTGCTGTTCTTCAGCTCCGACCATGTTGCTGTGTGATTATCTCAATTGGTTTTAATTGAGGCA

>In-frame_ENST00000456518_ENST00000289893_TCGA-CH-5788-01A_SCMH1_chr1_41608550_-_MACF1_chr1_39945470_length(amino acids)=279AA_start in transcript=203_stop in transcript=1042
MQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLARGRTNIELR
EKFILPEGASQGMTPFRSRGRRSKPSSRAASPTRSSSSASQSNHSCTSMPSSPATPASGTKVIPSSGSKLKRPTPTFHSSRTSLAGDTSN
SSSPASTGAKTNRADPKKSASRPGSRAGSRAGSRASSRRGSDASDFDLLETQSACSDTSESSAAGGQGNSRRGLNKPSKIPTMSKKTTTA

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Fusion Gene PPI Analysis for SCMH1-MACF1

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for SCMH1-MACF1

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for SCMH1-MACF1

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	SCMH1	C0004238	Atrial Fibrillation	2	CTD_human
Hgene	SCMH1	C0235480	Paroxysmal atrial fibrillation	2	CTD_human
Hgene	SCMH1	C2585653	Persistent atrial fibrillation	2	CTD_human
Hgene	SCMH1	C3468561	familial atrial fibrillation	2	CTD_human
Tgene	MACF1	C0036572	Seizures	2	GENOMICS_ENGLAND
Tgene	MACF1	C0266463	Lissencephaly	2	GENOMICS_ENGLAND
Tgene	MACF1	C1855677	Brainstem dysplasia	2	GENOMICS_ENGLAND
Tgene	MACF1	C3714756	Intellectual Disability	2	GENOMICS_ENGLAND