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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SCN8A-ATF1 (FusionGDB2 ID:79202)

Fusion Gene Summary for SCN8A-ATF1

check button Fusion gene summary
Fusion gene informationFusion gene name: SCN8A-ATF1
Fusion gene ID: 79202
HgeneTgene
Gene symbol

SCN8A

ATF1

Gene ID

6334

2668

Gene namesodium voltage-gated channel alpha subunit 8glial cell derived neurotrophic factor
SynonymsBFIS5|CERIII|CIAT|EIEE13|MED|MYOCL2|NaCh6|Nav1.6|PN4ATF|ATF1|ATF2|HFB1-GDNF|HSCR3
Cytomap

12q13.13

5p13.2

Type of geneprotein-codingprotein-coding
Descriptionsodium channel protein type 8 subunit alphahNa6/Scn8a voltage-gated sodium channelsodium channel, voltage gated, type VIII, alpha subunitvoltage-gated sodium channel subunit alpha Nav1.6voltage-gated sodium channel type VIII alpha proteinglial cell line-derived neurotrophic factorastrocyte-derived trophic factor
Modification date2020031320200314
UniProtAcc.

P18846

Ensembl transtripts involved in fusion geneENST00000546961, ENST00000550891, 
ENST00000354534, ENST00000545061, 
ENST00000262053, ENST00000539132, 
Fusion gene scores* DoF score7 X 8 X 5=28010 X 16 X 7=1120
# samples 816
** MAII scorelog2(8/280*10)=-1.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(16/1120*10)=-2.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SCN8A [Title/Abstract] AND ATF1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSCN8A(52184286)-ATF1(51189692), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneATF1

GO:0001755

neural crest cell migration

15242795

TgeneATF1

GO:0008284

positive regulation of cell proliferation

22897442

TgeneATF1

GO:0031175

neuron projection development

15242795

TgeneATF1

GO:0032770

positive regulation of monooxygenase activity

12358785

TgeneATF1

GO:0043524

negative regulation of neuron apoptotic process

8493557

TgeneATF1

GO:0045944

positive regulation of transcription by RNA polymerase II

12358785

TgeneATF1

GO:0048255

mRNA stabilization

12358785

TgeneATF1

GO:0051584

regulation of dopamine uptake involved in synaptic transmission

8493557

TgeneATF1

GO:0072107

positive regulation of ureteric bud formation

8657307

TgeneATF1

GO:0090190

positive regulation of branching involved in ureteric bud morphogenesis

8657307|17229286

TgeneATF1

GO:2001240

negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

10921886


check buttonFusion gene breakpoints across SCN8A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across ATF1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LGGTCGA-DH-A66G-01ASCN8Achr12

52184286

+ATF1chr12

51189692

+
ChimerDB4LGGTCGA-DH-A66GSCN8Achr12

52184286

+ATF1chr12

51189691

+
ChimerDB4LGGTCGA-DH-A66GSCN8Achr12

52184286

+ATF1chr12

51189692

+
ChimerDB4LGGTCGA-DH-A66G-01ASCN8Achr12

52184286

-ATF1chr12

51189692

+


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Fusion Gene ORF analysis for SCN8A-ATF1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
intron-3CDSENST00000546961ENST00000262053SCN8Achr12

52184286

+ATF1chr12

51189692

+
intron-intronENST00000546961ENST00000539132SCN8Achr12

52184286

+ATF1chr12

51189692

+
intron-3CDSENST00000550891ENST00000262053SCN8Achr12

52184286

+ATF1chr12

51189692

+
intron-intronENST00000550891ENST00000539132SCN8Achr12

52184286

+ATF1chr12

51189692

+
In-frameENST00000354534ENST00000262053SCN8Achr12

52184286

+ATF1chr12

51189692

+
5CDS-intronENST00000354534ENST00000539132SCN8Achr12

52184286

+ATF1chr12

51189692

+
In-frameENST00000545061ENST00000262053SCN8Achr12

52184286

+ATF1chr12

51189692

+
5CDS-intronENST00000545061ENST00000539132SCN8Achr12

52184286

+ATF1chr12

51189692

+
intron-3CDSENST00000546961ENST00000262053SCN8Achr12

52184286

+ATF1chr12

51189691

+
intron-intronENST00000546961ENST00000539132SCN8Achr12

52184286

+ATF1chr12

51189691

+
intron-3CDSENST00000550891ENST00000262053SCN8Achr12

52184286

+ATF1chr12

51189691

+
intron-intronENST00000550891ENST00000539132SCN8Achr12

52184286

+ATF1chr12

51189691

+
In-frameENST00000354534ENST00000262053SCN8Achr12

52184286

+ATF1chr12

51189691

+
5CDS-intronENST00000354534ENST00000539132SCN8Achr12

52184286

+ATF1chr12

51189691

+
In-frameENST00000545061ENST00000262053SCN8Achr12

52184286

+ATF1chr12

51189691

+
5CDS-intronENST00000545061ENST00000539132SCN8Achr12

52184286

+ATF1chr12

51189691

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000354534SCN8Achr1252184286+ENST00000262053ATF1chr1251189692+6768470216054241754
ENST00000545061SCN8Achr1252184286+ENST00000262053ATF1chr1251189692+652144553651771713
ENST00000354534SCN8Achr1252184286+ENST00000262053ATF1chr1251189691+6768470216054241754
ENST00000545061SCN8Achr1252184286+ENST00000262053ATF1chr1251189691+652144553651771713

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000354534ENST00000262053SCN8Achr1252184286+ATF1chr1251189692+0.0004251530.99957484
ENST00000545061ENST00000262053SCN8Achr1252184286+ATF1chr1251189692+0.0005499390.99945
ENST00000354534ENST00000262053SCN8Achr1252184286+ATF1chr1251189691+0.0004251530.99957484
ENST00000545061ENST00000262053SCN8Achr1252184286+ATF1chr1251189691+0.0005499390.99945

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Fusion Genomic Features for SCN8A-ATF1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SCN8Achr1252184286+ATF1chr1251189691+3.07E-050.99996924
SCN8Achr1252184286+ATF1chr1251189691+3.07E-050.99996924
SCN8Achr1252184286+ATF1chr1251189691+3.07E-050.99996924
SCN8Achr1252184286+ATF1chr1251189691+3.07E-050.99996924

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SCN8A-ATF1


check button Go to

FGviewer for the breakpoints of chr12:52184286-chr12:51189692

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ATF1

P18846

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation. {ECO:0000269|PubMed:18794154, ECO:0000269|PubMed:20980392}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271400_14211508.01981.0IntramembranePore-forming
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527356_3801508.01981.0IntramembranePore-forming
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527922_9421508.01981.0IntramembranePore-forming
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251400_14211467.01940.0IntramembranePore-forming
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325356_3801467.01940.0IntramembranePore-forming
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325922_9421467.01940.0IntramembranePore-forming
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271400_14211508.01981.0IntramembranePore-forming
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527356_3801508.01981.0IntramembranePore-forming
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527922_9421508.01981.0IntramembranePore-forming
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251400_14211467.01940.0IntramembranePore-forming
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325356_3801467.01940.0IntramembranePore-forming
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325922_9421467.01940.0IntramembranePore-forming
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527893_9001508.01981.0Nucleotide bindingATP
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325893_9001467.01940.0Nucleotide bindingATP
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527893_9001508.01981.0Nucleotide bindingATP
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325893_9001467.01940.0Nucleotide bindingATP
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527114_4421508.01981.0RepeatI
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271180_14951508.01981.0RepeatIII
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527735_10071508.01981.0RepeatII
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325114_4421467.01940.0RepeatI
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325735_10071467.01940.0RepeatII
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527114_4421508.01981.0RepeatI
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271180_14951508.01981.0RepeatIII
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527735_10071508.01981.0RepeatII
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325114_4421467.01940.0RepeatI
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325735_10071467.01940.0RepeatII
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271218_12301508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271250_12631508.01981.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271283_12901508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271310_13261508.01981.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271347_13991508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271422_14381508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527152_1581508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527180_1931508.01981.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271_1321508.01981.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527212_2171508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527235_2531508.01981.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527274_3551508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527381_3871508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527409_7531508.01981.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527773_7831508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527804_8171508.01981.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527838_8391508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527858_8731508.01981.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527893_9211508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527943_9551508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527977_11991508.01981.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251218_12301467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251250_12631467.01940.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251283_12901467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251310_13261467.01940.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251347_13991467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251422_14381467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325152_1581467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325180_1931467.01940.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251_1321467.01940.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325212_2171467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325235_2531467.01940.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325274_3551467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325381_3871467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325409_7531467.01940.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325773_7831467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325804_8171467.01940.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325838_8391467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325858_8731467.01940.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325893_9211467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325943_9551467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325977_11991467.01940.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271218_12301508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271250_12631508.01981.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271283_12901508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271310_13261508.01981.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271347_13991508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271422_14381508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527152_1581508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527180_1931508.01981.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271_1321508.01981.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527212_2171508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527235_2531508.01981.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527274_3551508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527381_3871508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527409_7531508.01981.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527773_7831508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527804_8171508.01981.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527838_8391508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527858_8731508.01981.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527893_9211508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527943_9551508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527977_11991508.01981.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251218_12301467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251250_12631467.01940.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251283_12901467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251310_13261467.01940.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251347_13991467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251422_14381467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325152_1581467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325180_1931467.01940.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251_1321467.01940.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325212_2171467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325235_2531467.01940.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325274_3551467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325381_3871467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325409_7531467.01940.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325773_7831467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325804_8171467.01940.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325838_8391467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325858_8731467.01940.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325893_9211467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325943_9551467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325977_11991467.01940.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271200_12171508.01981.0TransmembraneHelical%3B Name%3DS1 of repeat III
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271231_12491508.01981.0TransmembraneHelical%3B Name%3DS2 of repeat III
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271264_12821508.01981.0TransmembraneHelical%3B Name%3DS3 of repeat III
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271291_13091508.01981.0TransmembraneHelical%3B Name%3DS4 of repeat III
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271327_13461508.01981.0TransmembraneHelical%3B Name%3DS5 of repeat III
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527133_1511508.01981.0TransmembraneHelical%3B Name%3DS1 of repeat I
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271439_14601508.01981.0TransmembraneHelical%3B Name%3DS6 of repeat III
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527159_1791508.01981.0TransmembraneHelical%3B Name%3DS2 of repeat I
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527194_2111508.01981.0TransmembraneHelical%3B Name%3DS3 of repeat I
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527218_2341508.01981.0TransmembraneHelical%3B Name%3DS4 of repeat I
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527254_2731508.01981.0TransmembraneHelical%3B Name%3DS5 of repeat I
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527388_4081508.01981.0TransmembraneHelical%3B Name%3DS6 of repeat I
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527754_7721508.01981.0TransmembraneHelical%3B Name%3DS1 of repeat II
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527784_8031508.01981.0TransmembraneHelical%3B Name%3DS2 of repeat II
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527818_8371508.01981.0TransmembraneHelical%3B Name%3DS3 of repeat II
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527840_8571508.01981.0TransmembraneHelical%3B Name%3DS4 of repeat II
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527874_8921508.01981.0TransmembraneHelical%3B Name%3DS5 of repeat II
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+2527956_9761508.01981.0TransmembraneHelical%3B Name%3DS6 of repeat II
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251200_12171467.01940.0TransmembraneHelical%3B Name%3DS1 of repeat III
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251231_12491467.01940.0TransmembraneHelical%3B Name%3DS2 of repeat III
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251264_12821467.01940.0TransmembraneHelical%3B Name%3DS3 of repeat III
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251291_13091467.01940.0TransmembraneHelical%3B Name%3DS4 of repeat III
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251327_13461467.01940.0TransmembraneHelical%3B Name%3DS5 of repeat III
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325133_1511467.01940.0TransmembraneHelical%3B Name%3DS1 of repeat I
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251439_14601467.01940.0TransmembraneHelical%3B Name%3DS6 of repeat III
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325159_1791467.01940.0TransmembraneHelical%3B Name%3DS2 of repeat I
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325194_2111467.01940.0TransmembraneHelical%3B Name%3DS3 of repeat I
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325218_2341467.01940.0TransmembraneHelical%3B Name%3DS4 of repeat I
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325254_2731467.01940.0TransmembraneHelical%3B Name%3DS5 of repeat I
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325388_4081467.01940.0TransmembraneHelical%3B Name%3DS6 of repeat I
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325754_7721467.01940.0TransmembraneHelical%3B Name%3DS1 of repeat II
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325784_8031467.01940.0TransmembraneHelical%3B Name%3DS2 of repeat II
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325818_8371467.01940.0TransmembraneHelical%3B Name%3DS3 of repeat II
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325840_8571467.01940.0TransmembraneHelical%3B Name%3DS4 of repeat II
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325874_8921467.01940.0TransmembraneHelical%3B Name%3DS5 of repeat II
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+2325956_9761467.01940.0TransmembraneHelical%3B Name%3DS6 of repeat II
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271200_12171508.01981.0TransmembraneHelical%3B Name%3DS1 of repeat III
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271231_12491508.01981.0TransmembraneHelical%3B Name%3DS2 of repeat III
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271264_12821508.01981.0TransmembraneHelical%3B Name%3DS3 of repeat III
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271291_13091508.01981.0TransmembraneHelical%3B Name%3DS4 of repeat III
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271327_13461508.01981.0TransmembraneHelical%3B Name%3DS5 of repeat III
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527133_1511508.01981.0TransmembraneHelical%3B Name%3DS1 of repeat I
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271439_14601508.01981.0TransmembraneHelical%3B Name%3DS6 of repeat III
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527159_1791508.01981.0TransmembraneHelical%3B Name%3DS2 of repeat I
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527194_2111508.01981.0TransmembraneHelical%3B Name%3DS3 of repeat I
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527218_2341508.01981.0TransmembraneHelical%3B Name%3DS4 of repeat I
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527254_2731508.01981.0TransmembraneHelical%3B Name%3DS5 of repeat I
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527388_4081508.01981.0TransmembraneHelical%3B Name%3DS6 of repeat I
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527754_7721508.01981.0TransmembraneHelical%3B Name%3DS1 of repeat II
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527784_8031508.01981.0TransmembraneHelical%3B Name%3DS2 of repeat II
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527818_8371508.01981.0TransmembraneHelical%3B Name%3DS3 of repeat II
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527840_8571508.01981.0TransmembraneHelical%3B Name%3DS4 of repeat II
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527874_8921508.01981.0TransmembraneHelical%3B Name%3DS5 of repeat II
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+2527956_9761508.01981.0TransmembraneHelical%3B Name%3DS6 of repeat II
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251200_12171467.01940.0TransmembraneHelical%3B Name%3DS1 of repeat III
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251231_12491467.01940.0TransmembraneHelical%3B Name%3DS2 of repeat III
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251264_12821467.01940.0TransmembraneHelical%3B Name%3DS3 of repeat III
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251291_13091467.01940.0TransmembraneHelical%3B Name%3DS4 of repeat III
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251327_13461467.01940.0TransmembraneHelical%3B Name%3DS5 of repeat III
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325133_1511467.01940.0TransmembraneHelical%3B Name%3DS1 of repeat I
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251439_14601467.01940.0TransmembraneHelical%3B Name%3DS6 of repeat III
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325159_1791467.01940.0TransmembraneHelical%3B Name%3DS2 of repeat I
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325194_2111467.01940.0TransmembraneHelical%3B Name%3DS3 of repeat I
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325218_2341467.01940.0TransmembraneHelical%3B Name%3DS4 of repeat I
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325254_2731467.01940.0TransmembraneHelical%3B Name%3DS5 of repeat I
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325388_4081467.01940.0TransmembraneHelical%3B Name%3DS6 of repeat I
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325754_7721467.01940.0TransmembraneHelical%3B Name%3DS1 of repeat II
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325784_8031467.01940.0TransmembraneHelical%3B Name%3DS2 of repeat II
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325818_8371467.01940.0TransmembraneHelical%3B Name%3DS3 of repeat II
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325840_8571467.01940.0TransmembraneHelical%3B Name%3DS4 of repeat II
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325874_8921467.01940.0TransmembraneHelical%3B Name%3DS5 of repeat II
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+2325956_9761467.01940.0TransmembraneHelical%3B Name%3DS6 of repeat II
TgeneATF1chr12:52184286chr12:51189691ENST0000026205317213_27131.0272.0DomainbZIP
TgeneATF1chr12:52184286chr12:51189691ENST000002620531731_9031.0272.0DomainKID
TgeneATF1chr12:52184286chr12:51189692ENST0000026205317213_27131.0272.0DomainbZIP
TgeneATF1chr12:52184286chr12:51189692ENST000002620531731_9031.0272.0DomainKID
TgeneATF1chr12:52184286chr12:51189691ENST0000026205317215_23931.0272.0RegionBasic motif
TgeneATF1chr12:52184286chr12:51189691ENST0000026205317241_26231.0272.0RegionLeucine-zipper
TgeneATF1chr12:52184286chr12:51189692ENST0000026205317215_23931.0272.0RegionBasic motif
TgeneATF1chr12:52184286chr12:51189692ENST0000026205317241_26231.0272.0RegionLeucine-zipper

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271895_19241508.01981.0DomainIQ
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251895_19241467.01940.0DomainIQ
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271895_19241508.01981.0DomainIQ
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251895_19241467.01940.0DomainIQ
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271691_17131508.01981.0IntramembranePore-forming
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251691_17131467.01940.0IntramembranePore-forming
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271691_17131508.01981.0IntramembranePore-forming
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251691_17131467.01940.0IntramembranePore-forming
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271504_18011508.01981.0RepeatIV
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251180_14951467.01940.0RepeatIII
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251504_18011467.01940.0RepeatIV
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271504_18011508.01981.0RepeatIV
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251180_14951467.01940.0RepeatIII
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251504_18011467.01940.0RepeatIV
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271461_15231508.01981.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271542_15521508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271572_15831508.01981.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271602_16141508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271632_16501508.01981.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271669_16901508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271714_17421508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271766_19801508.01981.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251461_15231467.01940.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251542_15521467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251572_15831467.01940.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251602_16141467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251632_16501467.01940.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251669_16901467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251714_17421467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251766_19801467.01940.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271461_15231508.01981.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271542_15521508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271572_15831508.01981.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271602_16141508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271632_16501508.01981.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271669_16901508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271714_17421508.01981.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271766_19801508.01981.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251461_15231467.01940.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251542_15521467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251572_15831467.01940.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251602_16141467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251632_16501467.01940.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251669_16901467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251714_17421467.01940.0Topological domainExtracellular
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251766_19801467.01940.0Topological domainCytoplasmic
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271524_15411508.01981.0TransmembraneHelical%3B Name%3DS1 of repeat IV
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271553_15711508.01981.0TransmembraneHelical%3B Name%3DS2 of repeat IV
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271584_16011508.01981.0TransmembraneHelical%3B Name%3DS3 of repeat IV
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271615_16311508.01981.0TransmembraneHelical%3B Name%3DS4 of repeat IV
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271651_16681508.01981.0TransmembraneHelical%3B Name%3DS5 of repeat IV
HgeneSCN8Achr12:52184286chr12:51189691ENST00000354534+25271743_17651508.01981.0TransmembraneHelical%3B Name%3DS6 of repeat IV
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251524_15411467.01940.0TransmembraneHelical%3B Name%3DS1 of repeat IV
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251553_15711467.01940.0TransmembraneHelical%3B Name%3DS2 of repeat IV
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251584_16011467.01940.0TransmembraneHelical%3B Name%3DS3 of repeat IV
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251615_16311467.01940.0TransmembraneHelical%3B Name%3DS4 of repeat IV
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251651_16681467.01940.0TransmembraneHelical%3B Name%3DS5 of repeat IV
HgeneSCN8Achr12:52184286chr12:51189691ENST00000545061+23251743_17651467.01940.0TransmembraneHelical%3B Name%3DS6 of repeat IV
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271524_15411508.01981.0TransmembraneHelical%3B Name%3DS1 of repeat IV
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271553_15711508.01981.0TransmembraneHelical%3B Name%3DS2 of repeat IV
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271584_16011508.01981.0TransmembraneHelical%3B Name%3DS3 of repeat IV
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271615_16311508.01981.0TransmembraneHelical%3B Name%3DS4 of repeat IV
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271651_16681508.01981.0TransmembraneHelical%3B Name%3DS5 of repeat IV
HgeneSCN8Achr12:52184286chr12:51189692ENST00000354534+25271743_17651508.01981.0TransmembraneHelical%3B Name%3DS6 of repeat IV
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251524_15411467.01940.0TransmembraneHelical%3B Name%3DS1 of repeat IV
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251553_15711467.01940.0TransmembraneHelical%3B Name%3DS2 of repeat IV
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251584_16011467.01940.0TransmembraneHelical%3B Name%3DS3 of repeat IV
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251615_16311467.01940.0TransmembraneHelical%3B Name%3DS4 of repeat IV
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251651_16681467.01940.0TransmembraneHelical%3B Name%3DS5 of repeat IV
HgeneSCN8Achr12:52184286chr12:51189692ENST00000545061+23251743_17651467.01940.0TransmembraneHelical%3B Name%3DS6 of repeat IV


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Fusion Gene Sequence for SCN8A-ATF1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000354534_ENST00000262053_TCGA-DH-A66G-01A_SCN8A_chr12_52184286_+_ATF1_chr12_51189692_length(transcript)=6768nt_BP=4702nt
GAGCGCTCCAAGATGGCGCCCACCGCAGTCCCGCCCGCCGCATCCTCGGCGCCTTTGCAGTCCGGCCGCGCCTCCCGGGCCCCGCGTTAG
GGCCGCCGCTGCCTCCCTCGCCGCCGCCGCTGCCAGCTGACCTGTCCTGGACGCAGCATAACTAACGAAGCTGCTGCAGGATGAGAAGAT
GGCAGCGCGGCTGCTTGCACCACCAGGCCCTGATAGTTTCAAGCCTTTCACCCCTGAGTCACTGGCAAACATTGAGAGGCGCATTGCTGA
GAGCAAGCTCAAGAAACCACCAAAGGCCGATGGCAGTCATCGGGAGGACGATGAGGACAGCAAGCCCAAGCCAAACAGCGACCTGGAAGC
AGGGAAGAGTTTGCCTTTCATCTACGGGGACATCCCCCAAGGCCTGGTTGCAGTTCCCCTGGAGGACTTTGACCCATACTATTTGACGCA
GAAAACCTTTGTAGTATTAAACAGAGGGAAAACTCTCTTCAGATTTAGTGCCACGCCTGCCTTGTACATTTTAAGTCCTTTTAACCTGAT
AAGAAGAATAGCTATTAAAATTTTGATACATTCAGTATTTAGCATGATCATTATGTGCACTATTTTGACCAACTGTGTATTCATGACTTT
TAGTAACCCTCCTGACTGGTCGAAGAATGTGGAGTACACGTTCACAGGGATTTATACATTTGAATCACTAGTGAAAATCATTGCAAGAGG
TTTCTGCATAGATGGCTTTACCTTTTTACGGGACCCATGGAACTGGTTAGATTTCAGTGTCATCATGATGGCGTATATAACAGAGTTTGT
AAACCTAGGCAATGTTTCAGCTCTACGCACTTTCAGGGTACTGAGGGCTTTGAAAACTATTTCGGTAATCCCAGGCCTGAAGACAATTGT
GGGTGCCCTGATTCAGTCTGTGAAGAAACTGTCAGATGTGATGATCCTGACAGTGTTCTGCCTGAGTGTTTTTGCCTTGATCGGACTGCA
GCTGTTCATGGGGAACCTTCGAAACAAGTGTGTTGTGTGGCCCATAAACTTCAACGAGAGCTATCTTGAAAATGGCACCAAAGGCTTTGA
TTGGGAAGAGTATATCAACAATAAAACAAATTTCTACACAGTTCCTGGCATGCTGGAACCTTTACTCTGTGGGAACAGTTCTGATGCTGG
GCAATGCCCAGAGGGATACCAGTGTATGAAAGCAGGAAGGAACCCCAACTATGGTTACACAAGTTTTGACACTTTTAGCTGGGCCTTCTT
GGCATTATTTCGCCTTATGACCCAGGACTATTGGGAAAACTTGTATCAATTGACTTTACGAGCAGCCGGGAAAACATACATGATCTTCTT
CGTCTTGGTCATCTTTGTGGGTTCTTTCTATCTGGTGAACTTGATCTTGGCTGTGGTGGCCATGGCTTATGAAGAACAGAATCAGGCAAC
ACTGGAGGAGGCAGAACAAAAAGAGGCTGAATTTAAAGCAATGTTGGAGCAACTTAAGAAGCAACAGGAAGAGGCACAGGCTGCTGCGAT
GGCCACTTCAGCAGGAACTGTCTCAGAAGATGCCATAGAGGAAGAAGGTGAAGAAGGAGGGGGCTCCCCTCGGAGCTCTTCTGAAATCTC
TAAACTCAGCTCAAAGAGTGCAAAGGAAAGACGTAACAGGAGAAAGAAGAGGAAGCAAAAGGAACTCTCTGAAGGAGAGGAGAAAGGGGA
TCCCGAGAAGGTGTTTAAGTCAGAGTCAGAAGATGGCATGAGAAGGAAGGCCTTTCGGCTGCCAGACAACAGAATAGGGAGGAAATTTTC
CATCATGAATCAGTCACTGCTCAGCATCCCAGGCTCGCCCTTCCTCTCCCGCCACAACAGCAAGAGCAGCATCTTCAGTTTCAGGGGACC
TGGGCGGTTCCGAGACCCGGGCTCCGAGAATGAGTTCGCGGATGACGAGCACAGCACGGTGGAGGAGAGCGAGGGCCGCCGGGACTCCCT
CTTCATCCCCATCCGGGCCCGCGAGCGCCGGAGCAGCTACAGCGGCTACAGCGGCTACAGCCAGGGCAGCCGCTCCTCGCGCATCTTCCC
CAGCCTGCGGCGCAGCGTGAAGCGCAACAGCACGGTGGACTGCAACGGCGTGGTGTCCCTCATCGGCGGCCCCGGCTCCCACATCGGCGG
GCGTCTCCTGCCAGAGGCTACAACTGAGGTGGAAATTAAGAAGAAAGGCCCTGGATCTCTTTTAGTTTCCATGGACCAATTAGCCTCCTA
CGGGCGGAAGGACAGAATCAACAGTATAATGAGTGTTGTTACAAATACACTAGTAGAAGAACTGGAAGAGTCTCAGAGAAAGTGCCCGCC
ATGCTGGTATAAATTTGCCAACACTTTCCTCATCTGGGAGTGCCACCCCTACTGGATAAAACTGAAAGAGATTGTGAACTTGATAGTTAT
GGACCCTTTTGTGGATTTAGCCATCACCATCTGCATCGTCCTGAATACACTGTTTATGGCAATGGAGCACCATCCTATGACACCACAATT
TGAACATGTCTTGGCTGTAGGAAATCTGGTTTTCACTGGAATTTTCACAGCGGAAATGTTCCTGAAGCTCATAGCCATGGATCCCTACTA
TTATTTCCAAGAAGGTTGGAACATTTTTGACGGATTTATTGTCTCCCTCAGTTTAATGGAACTGAGTCTAGCAGACGTGGAGGGGCTTTC
AGTGCTGCGATCTTTCCGATTGCTCCGAGTCTTCAAATTGGCCAAATCCTGGCCCACCCTGAACATGCTAATCAAGATTATTGGAAATTC
AGTGGGTGCCCTGGGCAACCTGACACTGGTGCTGGCCATTATTGTCTTCATCTTTGCCGTGGTGGGGATGCAACTCTTTGGAAAAAGCTA
CAAAGAGTGTGTCTGCAAGATCAACCAGGACTGTGAACTCCCTCGCTGGCATATGCATGACTTTTTCCATTCCTTCCTCATTGTCTTTCG
AGTGTTGTGCGGGGAGTGGATTGAGACCATGTGGGACTGCATGGAAGTGGCAGGCCAGGCCATGTGCCTCATTGTCTTTATGATGGTCAT
GGTGATTGGCAACTTGGTGGTGCTGAACCTGTTTCTGGCCTTGCTCCTGAGCTCCTTCAGTGCAGACAACCTGGCTGCCACAGATGACGA
TGGGGAAATGAACAACCTCCAGATCTCAGTGATCCGTATCAAGAAGGGTGTGGCCTGGACCAAACTAAAGGTGCACGCCTTCATGCAGGC
CCACTTTAAGCAGCGTGAGGCTGATGAGGTGAAGCCTCTGGATGAGTTGTATGAAAAGAAGGCCAACTGTATCGCCAATCACACCGGTGC
AGACATCCACCGGAATGGTGACTTCCAGAAGAATGGCAATGGCACAACCAGCGGCATTGGCAGCAGCGTGGAGAAGTACATCATTGATGA
GGACCACATGTCCTTCATCAACAACCCCAACTTGACTGTACGGGTACCCATTGCTGTGGGCGAGTCTGACTTTGAGAACCTCAACACAGA
GGATGTTAGCAGCGAGTCGGATCCTGAAGGCAGCAAAGATAAACTAGATGACACCAGCTCCTCTGAAGGAAGCACCATTGATATCAAACC
AGAAGTAGAAGAGGTCCCTGTGGAACAGCCTGAGGAATACTTGGATCCAGATGCCTGCTTCACAGAAGGTTGTGTCCAGCGGTTCAAGTG
CTGCCAGGTCAACATCGAGGAAGGGCTAGGCAAGTCTTGGTGGATCCTGCGGAAAACCTGCTTCCTCATCGTGGAGCACAACTGGTTTGA
GACCTTCATCATCTTCATGATTCTGCTGAGCAGTGGCGCCCTGGCCTTCGAGGACATCTACATTGAGCAGAGAAAGACCATCCGCACCAT
CCTGGAATATGCTGACAAAGTCTTCACCTATATCTTCATCCTGGAGATGTTGCTCAAGTGGACAGCCTATGGCTTCGTCAAGTTCTTCAC
CAATGCCTGGTGTTGGCTGGACTTCCTCATTGTGGCTGTCTCTTTAGTCAGCCTTATAGCTAATGCCCTGGGCTACTCGGAACTAGGTGC
CATAAAGTCCCTTAGGACCCTAAGAGCTTTGAGACCCTTAAGAGCCTTATCACGATTTGAAGGGATGAGGGTGGTGGTGAATGCCTTGGT
GGGCGCCATCCCCTCCATCATGAATGTGCTGCTGGTGTGTCTCATCTTCTGGCTGATTTTCAGCATCATGGGAGTTAACTTGTTTGCGGG
AAAGTACCACTACTGCTTTAATGAGACTTCTGAAATCCGATTTGAAATTGAAGATGTCAACAATAAAACTGAATGTGAAAAGCTTATGGA
GGGGAACAATACAGAGATCAGATGGAAGAACGTGAAGATCAACTTTGACAATGTTGGGGCAGGATACCTGGCCCTTCTTCAAGTAGCAAC
CTTCAAAGGCTGGATGGACATCATGTATGCAGCTGTAGATTCCCGGAAGCCTGATGAGCAGCCTAAGTATGAGGACAATATCTACATGTA
CATCTATTTTGTCATCTTCATCATCTTCGGCTCCTTCTTCACCCTGAACCTGTTCATTGGTGTCATCATTGATAACTTCAATCAACAAAA
GAAAAAGTTCGGAGGTCAGGACATCTTCATGACCGAAGAACAGAAGAAGTACTACAATGCCATGAAAAAGCTGGGCTCAAAGAAGCCACA
GAAACCTATTCCCCGCCCCTTGGTATCATCTTTATCAGAAAGTGAGGAGTCCCAGGACTCATCCGACAGCATAGGCTCCTCACAGAAAGC
CCACGGGATCCTAGCACGGCGCCCATCTTACAGAAAAATTTTGAAAGACTTATCTTCTGAAGATACACGGGGCAGAAAAGGAGACGGAGA
AAATTCTGGAGTTTCTGCTGCTGTCACTTCTATGTCTGTTCCAACTCCCATCTATCAGACTAGCAGCGGACAGTACATTGCCATTGCCCC
AAATGGAGCCTTACAGTTGGCAAGTCCAGGCACAGATGGAGTACAGGGACTTCAGACATTAACCATGACAAATTCAGGCAGTACTCAGCA
AGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGG
AGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTC
TCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAA
GAAAGAATATGTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGGA
TCTTTATTCCAATAAAAGTGTTTGATTCCTAAGAAAGAAAATATTTTTGTGGACATGCATAAAAATTAAATGGATTTCCTAGTGGAGTTT
TATAAATTAAAAGGTCAAAACTGAAGCTTTTTATTTAGGCTTTTCCAAATCAAGGATAAATATCTTACGCACGATATCTAGTGACAGAGG
AGAAAGTGGAAAATGACCTCAAGGAAGCTACGGGCACAACTGGAAGCTTTGTAGAAATTAAACATATTCAAGGAGCAAGAAATGAACTTT
CAGCAGTCTAAATTTTCTAAATAACCAATAGTTGCCAATCTAAAATGGCAGAGAAGATGAAATTTGATAAACTGAATTTTTTTTAAAAAT
CCATTTACCCTACAGGTTTGCATTTGTTTGCTGAAATTTACCTTTTTTTAGTTATATATATGTGTGTGTGTGTGTGTAATTTCTGCCAAT
AAATTCTAAATTACAAAGGTAAGAGAAAACCTAGTACATTACTAAATATATAAAGTATATGTTCTGATTATGTATACTTGTTCTAGTGTC
AAGTCTTTTTAAGTGGGTTTTTAAAAGTTTGTTATTGGACTTGAATGGATTTTTGAGACTAGGTTAATTATTTTTGAGGTCTTATCCTAA
AAGGCATCTAAGGTACATGAATGGAGTATGGTGATTTTATAACATTTTTTATCAGAATGGAAAAAGAACTGTTTAAAAGTTTGATACTTT
TAAATAGTTGGTTTTTTTGCTTACTCTGGTAATGATTTTCTACAAATACATAATAAATTGTTTTTTTGAGTCTATATTCTGTATGCAGTT
GAATATCCATTACTTATTCTGCTGTGCTTTAATAGAATGGAATGTTTACAGGCCCTTAAAATATTATTTTTAAAAAACCTTCTGAAGATA
CATACCAAAGTTTTTCCAAGAAGATTTTATAATCAATTTAATAATGTAAGGTTTATCAGATTCTATAATAGTATAGTTATTAAGGCAATT
TTATGTTAGAGACTATTTTGTAATGTAGTGAGTGGTACCTTTATAAGAAAAGTGACTGCCAATATATTTTTATAGCTGATCTTTATAAAT
TCTAATGTTGAGTTTTTAATGATTATTTTAAATGTTTATATAGTTTAGTAAAATTTGCATCTCAAAGTATCATTTTTATATTATGGGACG
TTTTCAGATTGGCTAATATTTGCATTGTAAATTTTGTATGCAGTTTATCTAAAATTCAAAAATACTGTCAGTACACCAGCGTTTAACATC
TATATTCCAATTTGTATACAGTTTAAAATTGTACTGCAAAACTATTGTGTGCTCTTACACAGTATGCATCATATTGTTGTCTGTGAAATT

>In-frame_ENST00000354534_ENST00000262053_TCGA-DH-A66G-01A_SCN8A_chr12_52184286_+_ATF1_chr12_51189692_length(amino acids)=1754AA_start in transcript=160_stop in transcript=5424
MLQDEKMAARLLAPPGPDSFKPFTPESLANIERRIAESKLKKPPKADGSHREDDEDSKPKPNSDLEAGKSLPFIYGDIPQGLVAVPLEDF
DPYYLTQKTFVVLNRGKTLFRFSATPALYILSPFNLIRRIAIKILIHSVFSMIIMCTILTNCVFMTFSNPPDWSKNVEYTFTGIYTFESL
VKIIARGFCIDGFTFLRDPWNWLDFSVIMMAYITEFVNLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSV
FALIGLQLFMGNLRNKCVVWPINFNESYLENGTKGFDWEEYINNKTNFYTVPGMLEPLLCGNSSDAGQCPEGYQCMKAGRNPNYGYTSFD
TFSWAFLALFRLMTQDYWENLYQLTLRAAGKTYMIFFVLVIFVGSFYLVNLILAVVAMAYEEQNQATLEEAEQKEAEFKAMLEQLKKQQE
EAQAAAMATSAGTVSEDAIEEEGEEGGGSPRSSSEISKLSSKSAKERRNRRKKRKQKELSEGEEKGDPEKVFKSESEDGMRRKAFRLPDN
RIGRKFSIMNQSLLSIPGSPFLSRHNSKSSIFSFRGPGRFRDPGSENEFADDEHSTVEESEGRRDSLFIPIRARERRSSYSGYSGYSQGS
RSSRIFPSLRRSVKRNSTVDCNGVVSLIGGPGSHIGGRLLPEATTEVEIKKKGPGSLLVSMDQLASYGRKDRINSIMSVVTNTLVEELEE
SQRKCPPCWYKFANTFLIWECHPYWIKLKEIVNLIVMDPFVDLAITICIVLNTLFMAMEHHPMTPQFEHVLAVGNLVFTGIFTAEMFLKL
IAMDPYYYFQEGWNIFDGFIVSLSLMELSLADVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGM
QLFGKSYKECVCKINQDCELPRWHMHDFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLIVFMMVMVIGNLVVLNLFLALLLSSFSADN
LAATDDDGEMNNLQISVIRIKKGVAWTKLKVHAFMQAHFKQREADEVKPLDELYEKKANCIANHTGADIHRNGDFQKNGNGTTSGIGSSV
EKYIIDEDHMSFINNPNLTVRVPIAVGESDFENLNTEDVSSESDPEGSKDKLDDTSSSEGSTIDIKPEVEEVPVEQPEEYLDPDACFTEG
CVQRFKCCQVNIEEGLGKSWWILRKTCFLIVEHNWFETFIIFMILLSSGALAFEDIYIEQRKTIRTILEYADKVFTYIFILEMLLKWTAY
GFVKFFTNAWCWLDFLIVAVSLVSLIANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALVGAIPSIMNVLLVCLIFWLIFSIM
GVNLFAGKYHYCFNETSEIRFEIEDVNNKTECEKLMEGNNTEIRWKNVKINFDNVGAGYLALLQVATFKGWMDIMYAAVDSRKPDEQPKY
EDNIYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLVSSLSESEESQDSSDS
IGSSQKAHGILARRPSYRKILKDLSSEDTRGRKGDGENSGVSAAVTSMSVPTPIYQTSSGQYIAIAPNGALQLASPGTDGVQGLQTLTMT
NSGSTQQGTTILQYAQTSDGQQILVPSNQVVVQTASGDMQTYQIRTTPSATSLPQTVVMTSPVTLTSQTTKTDDPQLKREIRLMKNREAA

--------------------------------------------------------------
>In-frame_ENST00000545061_ENST00000262053_TCGA-DH-A66G-01A_SCN8A_chr12_52184286_+_ATF1_chr12_51189692_length(transcript)=6521nt_BP=4455nt
AGCTGACCTGTCCTGGACGCAGCATAACTAACGAAGCTGCTGCAGGATGAGAAGATGGCAGCGCGGCTGCTTGCACCACCAGGCCCTGAT
AGTTTCAAGCCTTTCACCCCTGAGTCACTGGCAAACATTGAGAGGCGCATTGCTGAGAGCAAGCTCAAGAAACCACCAAAGGCCGATGGC
AGTCATCGGGAGGACGATGAGGACAGCAAGCCCAAGCCAAACAGCGACCTGGAAGCAGGGAAGAGTTTGCCTTTCATCTACGGGGACATC
CCCCAAGGCCTGGTTGCAGTTCCCCTGGAGGACTTTGACCCATACTATTTGACGCAGAAAACCTTTGTAGTATTAAACAGAGGGAAAACT
CTCTTCAGATTTAGTGCCACGCCTGCCTTGTACATTTTAAGTCCTTTTAACCTGATAAGAAGAATAGCTATTAAAATTTTGATACATTCA
GTATTTAGCATGATCATTATGTGCACTATTTTGACCAACTGTGTATTCATGACTTTTAGTAACCCTCCTGACTGGTCGAAGAATGTGGAG
TACACGTTCACAGGGATTTATACATTTGAATCACTAGTGAAAATCATTGCAAGAGGTTTCTGCATAGATGGCTTTACCTTTTTACGGGAC
CCATGGAACTGGTTAGATTTCAGTGTCATCATGATGGCGTATATAACAGAGTTTGTAAACCTAGGCAATGTTTCAGCTCTACGCACTTTC
AGGGTACTGAGGGCTTTGAAAACTATTTCGGTAATCCCAGGCCTGAAGACAATTGTGGGTGCCCTGATTCAGTCTGTGAAGAAACTGTCA
GATGTGATGATCCTGACAGTGTTCTGCCTGAGTGTTTTTGCCTTGATCGGACTGCAGCTGTTCATGGGGAACCTTCGAAACAAGTGTGTT
GTGTGGCCCATAAACTTCAACGAGAGCTATCTTGAAAATGGCACCAAAGGCTTTGATTGGGAAGAGTATATCAACAATAAAACAAATTTC
TACACAGTTCCTGGCATGCTGGAACCTTTACTCTGTGGGAACAGTTCTGATGCTGGGCAATGCCCAGAGGGATACCAGTGTATGAAAGCA
GGAAGGAACCCCAACTATGGTTACACAAGTTTTGACACTTTTAGCTGGGCCTTCTTGGCATTATTTCGCCTTATGACCCAGGACTATTGG
GAAAACTTGTATCAATTGACTTTACGAGCAGCCGGGAAAACATACATGATCTTCTTCGTCTTGGTCATCTTTGTGGGTTCTTTCTATCTG
GTGAACTTGATCTTGGCTGTGGTGGCCATGGCTTATGAAGAACAGAATCAGGCAACACTGGAGGAGGCAGAACAAAAAGAGGCTGAATTT
AAAGCAATGTTGGAGCAACTTAAGAAGCAACAGGAAGAGGCACAGGCTGCTGCGATGGCCACTTCAGCAGGAACTGTCTCAGAAGATGCC
ATAGAGGAAGAAGGTGAAGAAGGAGGGGGCTCCCCTCGGAGCTCTTCTGAAATCTCTAAACTCAGCTCAAAGAGTGCAAAGGAAAGACGT
AACAGGAGAAAGAAGAGGAAGCAAAAGGAACTCTCTGAAGGAGAGGAGAAAGGGGATCCCGAGAAGGTGTTTAAGTCAGAGTCAGAAGAT
GGCATGAGAAGGAAGGCCTTTCGGCTGCCAGACAACAGAATAGGGAGGAAATTTTCCATCATGAATCAGTCACTGCTCAGCATCCCAGGC
TCGCCCTTCCTCTCCCGCCACAACAGCAAGAGCAGCATCTTCAGTTTCAGGGGACCTGGGCGGTTCCGAGACCCGGGCTCCGAGAATGAG
TTCGCGGATGACGAGCACAGCACGGTGGAGGAGAGCGAGGGCCGCCGGGACTCCCTCTTCATCCCCATCCGGGCCCGCGAGCGCCGGAGC
AGCTACAGCGGCTACAGCGGCTACAGCCAGGGCAGCCGCTCCTCGCGCATCTTCCCCAGCCTGCGGCGCAGCGTGAAGCGCAACAGCACG
GTGGACTGCAACGGCGTGGTGTCCCTCATCGGCGGCCCCGGCTCCCACATCGGCGGGCGTCTCCTGCCAGAGGCTACAACTGAGGTGGAA
ATTAAGAAGAAAGGCCCTGGATCTCTTTTAGTTTCCATGGACCAATTAGCCTCCTACGGGCGGAAGGACAGAATCAACAGTATAATGAGT
GTTGTTACAAATACACTAGTAGAAGAACTGGAAGAGTCTCAGAGAAAGTGCCCGCCATGCTGGTATAAATTTGCCAACACTTTCCTCATC
TGGGAGTGCCACCCCTACTGGATAAAACTGAAAGAGATTGTGAACTTGATAGTTATGGACCCTTTTGTGGATTTAGCCATCACCATCTGC
ATCGTCCTGAATACACTGTTTATGGCAATGGAGCACCATCCTATGACACCACAATTTGAACATGTCTTGGCTGTAGGAAATCTGGTTTTC
ACTGGAATTTTCACAGCGGAAATGTTCCTGAAGCTCATAGCCATGGATCCCTACTATTATTTCCAAGAAGGTTGGAACATTTTTGACGGA
TTTATTGTCTCCCTCAGTTTAATGGAACTGAGTCTAGCAGACGTGGAGGGGCTTTCAGTGCTGCGATCTTTCCGATTGCTCCGAGTCTTC
AAATTGGCCAAATCCTGGCCCACCCTGAACATGCTAATCAAGATTATTGGAAATTCAGTGGGTGCCCTGGGCAACCTGACACTGGTGCTG
GCCATTATTGTCTTCATCTTTGCCGTGGTGGGGATGCAACTCTTTGGAAAAAGCTACAAAGAGTGTGTCTGCAAGATCAACCAGGACTGT
GAACTCCCTCGCTGGCATATGCATGACTTTTTCCATTCCTTCCTCATTGTCTTTCGAGTGTTGTGCGGGGAGTGGATTGAGACCATGTGG
GACTGCATGGAAGTGGCAGGCCAGGCCATGTGCCTCATTGTCTTTATGATGGTCATGGTGATTGGCAACTTGGTGGTGCTGAACCTGTTT
CTGGCCTTGCTCCTGAGCTCCTTCAGTGCAGACAACCTGGCTGCCACAGATGACGATGGGGAAATGAACAACCTCCAGATCTCAGTGATC
CGTATCAAGAAGGGTGTGGCCTGGACCAAACTAAAGGTGCACGCCTTCATGCAGGCCCACTTTAAGCAGCGTGAGGCTGATGAGGTGAAG
CCTCTGGATGAGTTGTATGAAAAGAAGGCCAACTGTATCGCCAATCACACCGGTGCAGACATCCACCGGAATGGTGACTTCCAGAAGAAT
GGCAATGGCACAACCAGCGGCATTGGCAGCAGCGTGGAGAAGTACATCATTGATGAGGACCACATGTCCTTCATCAACAACCCCAACTTG
ACTGTACGGGTACCCATTGCTGTGGGCGAGTCTGACTTTGAGAACCTCAACACAGAGGATGTTAGCAGCGAGTCGGATCCTGAAGGCAGC
AAAGATAAACTAGATGACACCAGCTCCTCTGAAGGAAGCACCATTGATATCAAACCAGAAGTAGAAGAGGTCCCTGTGGAACAGCCTGAG
GAATACTTGGATCCAGATGCCTGCTTCACAGAAGGTTGTGTCCAGCGGTTCAAGTGCTGCCAGGTCAACATCGAGGAAGGGCTAGGCAAG
TCTTGGTGGATCCTGCGGAAAACCTGCTTCCTCATCGTGGAGCACAACTGGTTTGAGACCTTCATCATCTTCATGATTCTGCTGAGCAGT
GGCGCCCTGGCCTTCGAGGACATCTACATTGAGCAGAGAAAGACCATCCGCACCATCCTGGAATATGCTGACAAAGTCTTCACCTATATC
TTCATCCTGGAGATGTTGCTCAAGTGGACAGCCTATGGCTTCGTCAAGTTCTTCACCAATGCCTGGTGTTGGCTGGACTTCCTCATTGTG
GCTGTGGTGGTGAATGCCTTGGTGGGCGCCATCCCCTCCATCATGAATGTGCTGCTGGTGTGTCTCATCTTCTGGCTGATTTTCAGCATC
ATGGGAGTTAACTTGTTTGCGGGAAAGTACCACTACTGCTTTAATGAGACTTCTGAAATCCGATTTGAAATTGAAGATGTCAACAATAAA
ACTGAATGTGAAAAGCTTATGGAGGGGAACAATACAGAGATCAGATGGAAGAACGTGAAGATCAACTTTGACAATGTTGGGGCAGGATAC
CTGGCCCTTCTTCAAGTAGCAACCTTCAAAGGCTGGATGGACATCATGTATGCAGCTGTAGATTCCCGGAAGCCTGATGAGCAGCCTAAG
TATGAGGACAATATCTACATGTACATCTATTTTGTCATCTTCATCATCTTCGGCTCCTTCTTCACCCTGAACCTGTTCATTGGTGTCATC
ATTGATAACTTCAATCAACAAAAGAAAAAGTTCGGAGGTCAGGACATCTTCATGACCGAAGAACAGAAGAAGTACTACAATGCCATGAAA
AAGCTGGGCTCAAAGAAGCCACAGAAACCTATTCCCCGCCCCTTGGTATCATCTTTATCAGAAAGTGAGGAGTCCCAGGACTCATCCGAC
AGCATAGGCTCCTCACAGAAAGCCCACGGGATCCTAGCACGGCGCCCATCTTACAGAAAAATTTTGAAAGACTTATCTTCTGAAGATACA
CGGGGCAGAAAAGGAGACGGAGAAAATTCTGGAGTTTCTGCTGCTGTCACTTCTATGTCTGTTCCAACTCCCATCTATCAGACTAGCAGC
GGACAGTACATTGCCATTGCCCCAAATGGAGCCTTACAGTTGGCAAGTCCAGGCACAGATGGAGTACAGGGACTTCAGACATTAACCATG
ACAAATTCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAG
GTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATG
ACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCT
GCTCGAGAATGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATA
GAAGAGTTAAAAACTTTGAAGGATCTTTATTCCAATAAAAGTGTTTGATTCCTAAGAAAGAAAATATTTTTGTGGACATGCATAAAAATT
AAATGGATTTCCTAGTGGAGTTTTATAAATTAAAAGGTCAAAACTGAAGCTTTTTATTTAGGCTTTTCCAAATCAAGGATAAATATCTTA
CGCACGATATCTAGTGACAGAGGAGAAAGTGGAAAATGACCTCAAGGAAGCTACGGGCACAACTGGAAGCTTTGTAGAAATTAAACATAT
TCAAGGAGCAAGAAATGAACTTTCAGCAGTCTAAATTTTCTAAATAACCAATAGTTGCCAATCTAAAATGGCAGAGAAGATGAAATTTGA
TAAACTGAATTTTTTTTAAAAATCCATTTACCCTACAGGTTTGCATTTGTTTGCTGAAATTTACCTTTTTTTAGTTATATATATGTGTGT
GTGTGTGTGTAATTTCTGCCAATAAATTCTAAATTACAAAGGTAAGAGAAAACCTAGTACATTACTAAATATATAAAGTATATGTTCTGA
TTATGTATACTTGTTCTAGTGTCAAGTCTTTTTAAGTGGGTTTTTAAAAGTTTGTTATTGGACTTGAATGGATTTTTGAGACTAGGTTAA
TTATTTTTGAGGTCTTATCCTAAAAGGCATCTAAGGTACATGAATGGAGTATGGTGATTTTATAACATTTTTTATCAGAATGGAAAAAGA
ACTGTTTAAAAGTTTGATACTTTTAAATAGTTGGTTTTTTTGCTTACTCTGGTAATGATTTTCTACAAATACATAATAAATTGTTTTTTT
GAGTCTATATTCTGTATGCAGTTGAATATCCATTACTTATTCTGCTGTGCTTTAATAGAATGGAATGTTTACAGGCCCTTAAAATATTAT
TTTTAAAAAACCTTCTGAAGATACATACCAAAGTTTTTCCAAGAAGATTTTATAATCAATTTAATAATGTAAGGTTTATCAGATTCTATA
ATAGTATAGTTATTAAGGCAATTTTATGTTAGAGACTATTTTGTAATGTAGTGAGTGGTACCTTTATAAGAAAAGTGACTGCCAATATAT
TTTTATAGCTGATCTTTATAAATTCTAATGTTGAGTTTTTAATGATTATTTTAAATGTTTATATAGTTTAGTAAAATTTGCATCTCAAAG
TATCATTTTTATATTATGGGACGTTTTCAGATTGGCTAATATTTGCATTGTAAATTTTGTATGCAGTTTATCTAAAATTCAAAAATACTG
TCAGTACACCAGCGTTTAACATCTATATTCCAATTTGTATACAGTTTAAAATTGTACTGCAAAACTATTGTGTGCTCTTACACAGTATGC

>In-frame_ENST00000545061_ENST00000262053_TCGA-DH-A66G-01A_SCN8A_chr12_52184286_+_ATF1_chr12_51189692_length(amino acids)=1713AA_start in transcript=36_stop in transcript=5177
MLQDEKMAARLLAPPGPDSFKPFTPESLANIERRIAESKLKKPPKADGSHREDDEDSKPKPNSDLEAGKSLPFIYGDIPQGLVAVPLEDF
DPYYLTQKTFVVLNRGKTLFRFSATPALYILSPFNLIRRIAIKILIHSVFSMIIMCTILTNCVFMTFSNPPDWSKNVEYTFTGIYTFESL
VKIIARGFCIDGFTFLRDPWNWLDFSVIMMAYITEFVNLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSV
FALIGLQLFMGNLRNKCVVWPINFNESYLENGTKGFDWEEYINNKTNFYTVPGMLEPLLCGNSSDAGQCPEGYQCMKAGRNPNYGYTSFD
TFSWAFLALFRLMTQDYWENLYQLTLRAAGKTYMIFFVLVIFVGSFYLVNLILAVVAMAYEEQNQATLEEAEQKEAEFKAMLEQLKKQQE
EAQAAAMATSAGTVSEDAIEEEGEEGGGSPRSSSEISKLSSKSAKERRNRRKKRKQKELSEGEEKGDPEKVFKSESEDGMRRKAFRLPDN
RIGRKFSIMNQSLLSIPGSPFLSRHNSKSSIFSFRGPGRFRDPGSENEFADDEHSTVEESEGRRDSLFIPIRARERRSSYSGYSGYSQGS
RSSRIFPSLRRSVKRNSTVDCNGVVSLIGGPGSHIGGRLLPEATTEVEIKKKGPGSLLVSMDQLASYGRKDRINSIMSVVTNTLVEELEE
SQRKCPPCWYKFANTFLIWECHPYWIKLKEIVNLIVMDPFVDLAITICIVLNTLFMAMEHHPMTPQFEHVLAVGNLVFTGIFTAEMFLKL
IAMDPYYYFQEGWNIFDGFIVSLSLMELSLADVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGM
QLFGKSYKECVCKINQDCELPRWHMHDFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLIVFMMVMVIGNLVVLNLFLALLLSSFSADN
LAATDDDGEMNNLQISVIRIKKGVAWTKLKVHAFMQAHFKQREADEVKPLDELYEKKANCIANHTGADIHRNGDFQKNGNGTTSGIGSSV
EKYIIDEDHMSFINNPNLTVRVPIAVGESDFENLNTEDVSSESDPEGSKDKLDDTSSSEGSTIDIKPEVEEVPVEQPEEYLDPDACFTEG
CVQRFKCCQVNIEEGLGKSWWILRKTCFLIVEHNWFETFIIFMILLSSGALAFEDIYIEQRKTIRTILEYADKVFTYIFILEMLLKWTAY
GFVKFFTNAWCWLDFLIVAVVVNALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKYHYCFNETSEIRFEIEDVNNKTECEKLMEGNNT
EIRWKNVKINFDNVGAGYLALLQVATFKGWMDIMYAAVDSRKPDEQPKYEDNIYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFG
GQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLVSSLSESEESQDSSDSIGSSQKAHGILARRPSYRKILKDLSSEDTRGRKGDGENSGV
SAAVTSMSVPTPIYQTSSGQYIAIAPNGALQLASPGTDGVQGLQTLTMTNSGSTQQGTTILQYAQTSDGQQILVPSNQVVVQTASGDMQT
YQIRTTPSATSLPQTVVMTSPVTLTSQTTKTDDPQLKREIRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKTLKDLYSN

--------------------------------------------------------------
>In-frame_ENST00000354534_ENST00000262053_TCGA-DH-A66G_SCN8A_chr12_52184286_+_ATF1_chr12_51189691_length(transcript)=6768nt_BP=4702nt
GAGCGCTCCAAGATGGCGCCCACCGCAGTCCCGCCCGCCGCATCCTCGGCGCCTTTGCAGTCCGGCCGCGCCTCCCGGGCCCCGCGTTAG
GGCCGCCGCTGCCTCCCTCGCCGCCGCCGCTGCCAGCTGACCTGTCCTGGACGCAGCATAACTAACGAAGCTGCTGCAGGATGAGAAGAT
GGCAGCGCGGCTGCTTGCACCACCAGGCCCTGATAGTTTCAAGCCTTTCACCCCTGAGTCACTGGCAAACATTGAGAGGCGCATTGCTGA
GAGCAAGCTCAAGAAACCACCAAAGGCCGATGGCAGTCATCGGGAGGACGATGAGGACAGCAAGCCCAAGCCAAACAGCGACCTGGAAGC
AGGGAAGAGTTTGCCTTTCATCTACGGGGACATCCCCCAAGGCCTGGTTGCAGTTCCCCTGGAGGACTTTGACCCATACTATTTGACGCA
GAAAACCTTTGTAGTATTAAACAGAGGGAAAACTCTCTTCAGATTTAGTGCCACGCCTGCCTTGTACATTTTAAGTCCTTTTAACCTGAT
AAGAAGAATAGCTATTAAAATTTTGATACATTCAGTATTTAGCATGATCATTATGTGCACTATTTTGACCAACTGTGTATTCATGACTTT
TAGTAACCCTCCTGACTGGTCGAAGAATGTGGAGTACACGTTCACAGGGATTTATACATTTGAATCACTAGTGAAAATCATTGCAAGAGG
TTTCTGCATAGATGGCTTTACCTTTTTACGGGACCCATGGAACTGGTTAGATTTCAGTGTCATCATGATGGCGTATATAACAGAGTTTGT
AAACCTAGGCAATGTTTCAGCTCTACGCACTTTCAGGGTACTGAGGGCTTTGAAAACTATTTCGGTAATCCCAGGCCTGAAGACAATTGT
GGGTGCCCTGATTCAGTCTGTGAAGAAACTGTCAGATGTGATGATCCTGACAGTGTTCTGCCTGAGTGTTTTTGCCTTGATCGGACTGCA
GCTGTTCATGGGGAACCTTCGAAACAAGTGTGTTGTGTGGCCCATAAACTTCAACGAGAGCTATCTTGAAAATGGCACCAAAGGCTTTGA
TTGGGAAGAGTATATCAACAATAAAACAAATTTCTACACAGTTCCTGGCATGCTGGAACCTTTACTCTGTGGGAACAGTTCTGATGCTGG
GCAATGCCCAGAGGGATACCAGTGTATGAAAGCAGGAAGGAACCCCAACTATGGTTACACAAGTTTTGACACTTTTAGCTGGGCCTTCTT
GGCATTATTTCGCCTTATGACCCAGGACTATTGGGAAAACTTGTATCAATTGACTTTACGAGCAGCCGGGAAAACATACATGATCTTCTT
CGTCTTGGTCATCTTTGTGGGTTCTTTCTATCTGGTGAACTTGATCTTGGCTGTGGTGGCCATGGCTTATGAAGAACAGAATCAGGCAAC
ACTGGAGGAGGCAGAACAAAAAGAGGCTGAATTTAAAGCAATGTTGGAGCAACTTAAGAAGCAACAGGAAGAGGCACAGGCTGCTGCGAT
GGCCACTTCAGCAGGAACTGTCTCAGAAGATGCCATAGAGGAAGAAGGTGAAGAAGGAGGGGGCTCCCCTCGGAGCTCTTCTGAAATCTC
TAAACTCAGCTCAAAGAGTGCAAAGGAAAGACGTAACAGGAGAAAGAAGAGGAAGCAAAAGGAACTCTCTGAAGGAGAGGAGAAAGGGGA
TCCCGAGAAGGTGTTTAAGTCAGAGTCAGAAGATGGCATGAGAAGGAAGGCCTTTCGGCTGCCAGACAACAGAATAGGGAGGAAATTTTC
CATCATGAATCAGTCACTGCTCAGCATCCCAGGCTCGCCCTTCCTCTCCCGCCACAACAGCAAGAGCAGCATCTTCAGTTTCAGGGGACC
TGGGCGGTTCCGAGACCCGGGCTCCGAGAATGAGTTCGCGGATGACGAGCACAGCACGGTGGAGGAGAGCGAGGGCCGCCGGGACTCCCT
CTTCATCCCCATCCGGGCCCGCGAGCGCCGGAGCAGCTACAGCGGCTACAGCGGCTACAGCCAGGGCAGCCGCTCCTCGCGCATCTTCCC
CAGCCTGCGGCGCAGCGTGAAGCGCAACAGCACGGTGGACTGCAACGGCGTGGTGTCCCTCATCGGCGGCCCCGGCTCCCACATCGGCGG
GCGTCTCCTGCCAGAGGCTACAACTGAGGTGGAAATTAAGAAGAAAGGCCCTGGATCTCTTTTAGTTTCCATGGACCAATTAGCCTCCTA
CGGGCGGAAGGACAGAATCAACAGTATAATGAGTGTTGTTACAAATACACTAGTAGAAGAACTGGAAGAGTCTCAGAGAAAGTGCCCGCC
ATGCTGGTATAAATTTGCCAACACTTTCCTCATCTGGGAGTGCCACCCCTACTGGATAAAACTGAAAGAGATTGTGAACTTGATAGTTAT
GGACCCTTTTGTGGATTTAGCCATCACCATCTGCATCGTCCTGAATACACTGTTTATGGCAATGGAGCACCATCCTATGACACCACAATT
TGAACATGTCTTGGCTGTAGGAAATCTGGTTTTCACTGGAATTTTCACAGCGGAAATGTTCCTGAAGCTCATAGCCATGGATCCCTACTA
TTATTTCCAAGAAGGTTGGAACATTTTTGACGGATTTATTGTCTCCCTCAGTTTAATGGAACTGAGTCTAGCAGACGTGGAGGGGCTTTC
AGTGCTGCGATCTTTCCGATTGCTCCGAGTCTTCAAATTGGCCAAATCCTGGCCCACCCTGAACATGCTAATCAAGATTATTGGAAATTC
AGTGGGTGCCCTGGGCAACCTGACACTGGTGCTGGCCATTATTGTCTTCATCTTTGCCGTGGTGGGGATGCAACTCTTTGGAAAAAGCTA
CAAAGAGTGTGTCTGCAAGATCAACCAGGACTGTGAACTCCCTCGCTGGCATATGCATGACTTTTTCCATTCCTTCCTCATTGTCTTTCG
AGTGTTGTGCGGGGAGTGGATTGAGACCATGTGGGACTGCATGGAAGTGGCAGGCCAGGCCATGTGCCTCATTGTCTTTATGATGGTCAT
GGTGATTGGCAACTTGGTGGTGCTGAACCTGTTTCTGGCCTTGCTCCTGAGCTCCTTCAGTGCAGACAACCTGGCTGCCACAGATGACGA
TGGGGAAATGAACAACCTCCAGATCTCAGTGATCCGTATCAAGAAGGGTGTGGCCTGGACCAAACTAAAGGTGCACGCCTTCATGCAGGC
CCACTTTAAGCAGCGTGAGGCTGATGAGGTGAAGCCTCTGGATGAGTTGTATGAAAAGAAGGCCAACTGTATCGCCAATCACACCGGTGC
AGACATCCACCGGAATGGTGACTTCCAGAAGAATGGCAATGGCACAACCAGCGGCATTGGCAGCAGCGTGGAGAAGTACATCATTGATGA
GGACCACATGTCCTTCATCAACAACCCCAACTTGACTGTACGGGTACCCATTGCTGTGGGCGAGTCTGACTTTGAGAACCTCAACACAGA
GGATGTTAGCAGCGAGTCGGATCCTGAAGGCAGCAAAGATAAACTAGATGACACCAGCTCCTCTGAAGGAAGCACCATTGATATCAAACC
AGAAGTAGAAGAGGTCCCTGTGGAACAGCCTGAGGAATACTTGGATCCAGATGCCTGCTTCACAGAAGGTTGTGTCCAGCGGTTCAAGTG
CTGCCAGGTCAACATCGAGGAAGGGCTAGGCAAGTCTTGGTGGATCCTGCGGAAAACCTGCTTCCTCATCGTGGAGCACAACTGGTTTGA
GACCTTCATCATCTTCATGATTCTGCTGAGCAGTGGCGCCCTGGCCTTCGAGGACATCTACATTGAGCAGAGAAAGACCATCCGCACCAT
CCTGGAATATGCTGACAAAGTCTTCACCTATATCTTCATCCTGGAGATGTTGCTCAAGTGGACAGCCTATGGCTTCGTCAAGTTCTTCAC
CAATGCCTGGTGTTGGCTGGACTTCCTCATTGTGGCTGTCTCTTTAGTCAGCCTTATAGCTAATGCCCTGGGCTACTCGGAACTAGGTGC
CATAAAGTCCCTTAGGACCCTAAGAGCTTTGAGACCCTTAAGAGCCTTATCACGATTTGAAGGGATGAGGGTGGTGGTGAATGCCTTGGT
GGGCGCCATCCCCTCCATCATGAATGTGCTGCTGGTGTGTCTCATCTTCTGGCTGATTTTCAGCATCATGGGAGTTAACTTGTTTGCGGG
AAAGTACCACTACTGCTTTAATGAGACTTCTGAAATCCGATTTGAAATTGAAGATGTCAACAATAAAACTGAATGTGAAAAGCTTATGGA
GGGGAACAATACAGAGATCAGATGGAAGAACGTGAAGATCAACTTTGACAATGTTGGGGCAGGATACCTGGCCCTTCTTCAAGTAGCAAC
CTTCAAAGGCTGGATGGACATCATGTATGCAGCTGTAGATTCCCGGAAGCCTGATGAGCAGCCTAAGTATGAGGACAATATCTACATGTA
CATCTATTTTGTCATCTTCATCATCTTCGGCTCCTTCTTCACCCTGAACCTGTTCATTGGTGTCATCATTGATAACTTCAATCAACAAAA
GAAAAAGTTCGGAGGTCAGGACATCTTCATGACCGAAGAACAGAAGAAGTACTACAATGCCATGAAAAAGCTGGGCTCAAAGAAGCCACA
GAAACCTATTCCCCGCCCCTTGGTATCATCTTTATCAGAAAGTGAGGAGTCCCAGGACTCATCCGACAGCATAGGCTCCTCACAGAAAGC
CCACGGGATCCTAGCACGGCGCCCATCTTACAGAAAAATTTTGAAAGACTTATCTTCTGAAGATACACGGGGCAGAAAAGGAGACGGAGA
AAATTCTGGAGTTTCTGCTGCTGTCACTTCTATGTCTGTTCCAACTCCCATCTATCAGACTAGCAGCGGACAGTACATTGCCATTGCCCC
AAATGGAGCCTTACAGTTGGCAAGTCCAGGCACAGATGGAGTACAGGGACTTCAGACATTAACCATGACAAATTCAGGCAGTACTCAGCA
AGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAGGTGGTCGTACAAACTGCATCAGG
AGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATGACATCTCCTGTGACTCTCACCTC
TCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCTGCTCGAGAATGTCGCAGAAAGAA
GAAAGAATATGTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATAGAAGAGTTAAAAACTTTGAAGGA
TCTTTATTCCAATAAAAGTGTTTGATTCCTAAGAAAGAAAATATTTTTGTGGACATGCATAAAAATTAAATGGATTTCCTAGTGGAGTTT
TATAAATTAAAAGGTCAAAACTGAAGCTTTTTATTTAGGCTTTTCCAAATCAAGGATAAATATCTTACGCACGATATCTAGTGACAGAGG
AGAAAGTGGAAAATGACCTCAAGGAAGCTACGGGCACAACTGGAAGCTTTGTAGAAATTAAACATATTCAAGGAGCAAGAAATGAACTTT
CAGCAGTCTAAATTTTCTAAATAACCAATAGTTGCCAATCTAAAATGGCAGAGAAGATGAAATTTGATAAACTGAATTTTTTTTAAAAAT
CCATTTACCCTACAGGTTTGCATTTGTTTGCTGAAATTTACCTTTTTTTAGTTATATATATGTGTGTGTGTGTGTGTAATTTCTGCCAAT
AAATTCTAAATTACAAAGGTAAGAGAAAACCTAGTACATTACTAAATATATAAAGTATATGTTCTGATTATGTATACTTGTTCTAGTGTC
AAGTCTTTTTAAGTGGGTTTTTAAAAGTTTGTTATTGGACTTGAATGGATTTTTGAGACTAGGTTAATTATTTTTGAGGTCTTATCCTAA
AAGGCATCTAAGGTACATGAATGGAGTATGGTGATTTTATAACATTTTTTATCAGAATGGAAAAAGAACTGTTTAAAAGTTTGATACTTT
TAAATAGTTGGTTTTTTTGCTTACTCTGGTAATGATTTTCTACAAATACATAATAAATTGTTTTTTTGAGTCTATATTCTGTATGCAGTT
GAATATCCATTACTTATTCTGCTGTGCTTTAATAGAATGGAATGTTTACAGGCCCTTAAAATATTATTTTTAAAAAACCTTCTGAAGATA
CATACCAAAGTTTTTCCAAGAAGATTTTATAATCAATTTAATAATGTAAGGTTTATCAGATTCTATAATAGTATAGTTATTAAGGCAATT
TTATGTTAGAGACTATTTTGTAATGTAGTGAGTGGTACCTTTATAAGAAAAGTGACTGCCAATATATTTTTATAGCTGATCTTTATAAAT
TCTAATGTTGAGTTTTTAATGATTATTTTAAATGTTTATATAGTTTAGTAAAATTTGCATCTCAAAGTATCATTTTTATATTATGGGACG
TTTTCAGATTGGCTAATATTTGCATTGTAAATTTTGTATGCAGTTTATCTAAAATTCAAAAATACTGTCAGTACACCAGCGTTTAACATC
TATATTCCAATTTGTATACAGTTTAAAATTGTACTGCAAAACTATTGTGTGCTCTTACACAGTATGCATCATATTGTTGTCTGTGAAATT

>In-frame_ENST00000354534_ENST00000262053_TCGA-DH-A66G_SCN8A_chr12_52184286_+_ATF1_chr12_51189691_length(amino acids)=1754AA_start in transcript=160_stop in transcript=5424
MLQDEKMAARLLAPPGPDSFKPFTPESLANIERRIAESKLKKPPKADGSHREDDEDSKPKPNSDLEAGKSLPFIYGDIPQGLVAVPLEDF
DPYYLTQKTFVVLNRGKTLFRFSATPALYILSPFNLIRRIAIKILIHSVFSMIIMCTILTNCVFMTFSNPPDWSKNVEYTFTGIYTFESL
VKIIARGFCIDGFTFLRDPWNWLDFSVIMMAYITEFVNLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSV
FALIGLQLFMGNLRNKCVVWPINFNESYLENGTKGFDWEEYINNKTNFYTVPGMLEPLLCGNSSDAGQCPEGYQCMKAGRNPNYGYTSFD
TFSWAFLALFRLMTQDYWENLYQLTLRAAGKTYMIFFVLVIFVGSFYLVNLILAVVAMAYEEQNQATLEEAEQKEAEFKAMLEQLKKQQE
EAQAAAMATSAGTVSEDAIEEEGEEGGGSPRSSSEISKLSSKSAKERRNRRKKRKQKELSEGEEKGDPEKVFKSESEDGMRRKAFRLPDN
RIGRKFSIMNQSLLSIPGSPFLSRHNSKSSIFSFRGPGRFRDPGSENEFADDEHSTVEESEGRRDSLFIPIRARERRSSYSGYSGYSQGS
RSSRIFPSLRRSVKRNSTVDCNGVVSLIGGPGSHIGGRLLPEATTEVEIKKKGPGSLLVSMDQLASYGRKDRINSIMSVVTNTLVEELEE
SQRKCPPCWYKFANTFLIWECHPYWIKLKEIVNLIVMDPFVDLAITICIVLNTLFMAMEHHPMTPQFEHVLAVGNLVFTGIFTAEMFLKL
IAMDPYYYFQEGWNIFDGFIVSLSLMELSLADVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGM
QLFGKSYKECVCKINQDCELPRWHMHDFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLIVFMMVMVIGNLVVLNLFLALLLSSFSADN
LAATDDDGEMNNLQISVIRIKKGVAWTKLKVHAFMQAHFKQREADEVKPLDELYEKKANCIANHTGADIHRNGDFQKNGNGTTSGIGSSV
EKYIIDEDHMSFINNPNLTVRVPIAVGESDFENLNTEDVSSESDPEGSKDKLDDTSSSEGSTIDIKPEVEEVPVEQPEEYLDPDACFTEG
CVQRFKCCQVNIEEGLGKSWWILRKTCFLIVEHNWFETFIIFMILLSSGALAFEDIYIEQRKTIRTILEYADKVFTYIFILEMLLKWTAY
GFVKFFTNAWCWLDFLIVAVSLVSLIANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALVGAIPSIMNVLLVCLIFWLIFSIM
GVNLFAGKYHYCFNETSEIRFEIEDVNNKTECEKLMEGNNTEIRWKNVKINFDNVGAGYLALLQVATFKGWMDIMYAAVDSRKPDEQPKY
EDNIYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLVSSLSESEESQDSSDS
IGSSQKAHGILARRPSYRKILKDLSSEDTRGRKGDGENSGVSAAVTSMSVPTPIYQTSSGQYIAIAPNGALQLASPGTDGVQGLQTLTMT
NSGSTQQGTTILQYAQTSDGQQILVPSNQVVVQTASGDMQTYQIRTTPSATSLPQTVVMTSPVTLTSQTTKTDDPQLKREIRLMKNREAA

--------------------------------------------------------------
>In-frame_ENST00000545061_ENST00000262053_TCGA-DH-A66G_SCN8A_chr12_52184286_+_ATF1_chr12_51189691_length(transcript)=6521nt_BP=4455nt
AGCTGACCTGTCCTGGACGCAGCATAACTAACGAAGCTGCTGCAGGATGAGAAGATGGCAGCGCGGCTGCTTGCACCACCAGGCCCTGAT
AGTTTCAAGCCTTTCACCCCTGAGTCACTGGCAAACATTGAGAGGCGCATTGCTGAGAGCAAGCTCAAGAAACCACCAAAGGCCGATGGC
AGTCATCGGGAGGACGATGAGGACAGCAAGCCCAAGCCAAACAGCGACCTGGAAGCAGGGAAGAGTTTGCCTTTCATCTACGGGGACATC
CCCCAAGGCCTGGTTGCAGTTCCCCTGGAGGACTTTGACCCATACTATTTGACGCAGAAAACCTTTGTAGTATTAAACAGAGGGAAAACT
CTCTTCAGATTTAGTGCCACGCCTGCCTTGTACATTTTAAGTCCTTTTAACCTGATAAGAAGAATAGCTATTAAAATTTTGATACATTCA
GTATTTAGCATGATCATTATGTGCACTATTTTGACCAACTGTGTATTCATGACTTTTAGTAACCCTCCTGACTGGTCGAAGAATGTGGAG
TACACGTTCACAGGGATTTATACATTTGAATCACTAGTGAAAATCATTGCAAGAGGTTTCTGCATAGATGGCTTTACCTTTTTACGGGAC
CCATGGAACTGGTTAGATTTCAGTGTCATCATGATGGCGTATATAACAGAGTTTGTAAACCTAGGCAATGTTTCAGCTCTACGCACTTTC
AGGGTACTGAGGGCTTTGAAAACTATTTCGGTAATCCCAGGCCTGAAGACAATTGTGGGTGCCCTGATTCAGTCTGTGAAGAAACTGTCA
GATGTGATGATCCTGACAGTGTTCTGCCTGAGTGTTTTTGCCTTGATCGGACTGCAGCTGTTCATGGGGAACCTTCGAAACAAGTGTGTT
GTGTGGCCCATAAACTTCAACGAGAGCTATCTTGAAAATGGCACCAAAGGCTTTGATTGGGAAGAGTATATCAACAATAAAACAAATTTC
TACACAGTTCCTGGCATGCTGGAACCTTTACTCTGTGGGAACAGTTCTGATGCTGGGCAATGCCCAGAGGGATACCAGTGTATGAAAGCA
GGAAGGAACCCCAACTATGGTTACACAAGTTTTGACACTTTTAGCTGGGCCTTCTTGGCATTATTTCGCCTTATGACCCAGGACTATTGG
GAAAACTTGTATCAATTGACTTTACGAGCAGCCGGGAAAACATACATGATCTTCTTCGTCTTGGTCATCTTTGTGGGTTCTTTCTATCTG
GTGAACTTGATCTTGGCTGTGGTGGCCATGGCTTATGAAGAACAGAATCAGGCAACACTGGAGGAGGCAGAACAAAAAGAGGCTGAATTT
AAAGCAATGTTGGAGCAACTTAAGAAGCAACAGGAAGAGGCACAGGCTGCTGCGATGGCCACTTCAGCAGGAACTGTCTCAGAAGATGCC
ATAGAGGAAGAAGGTGAAGAAGGAGGGGGCTCCCCTCGGAGCTCTTCTGAAATCTCTAAACTCAGCTCAAAGAGTGCAAAGGAAAGACGT
AACAGGAGAAAGAAGAGGAAGCAAAAGGAACTCTCTGAAGGAGAGGAGAAAGGGGATCCCGAGAAGGTGTTTAAGTCAGAGTCAGAAGAT
GGCATGAGAAGGAAGGCCTTTCGGCTGCCAGACAACAGAATAGGGAGGAAATTTTCCATCATGAATCAGTCACTGCTCAGCATCCCAGGC
TCGCCCTTCCTCTCCCGCCACAACAGCAAGAGCAGCATCTTCAGTTTCAGGGGACCTGGGCGGTTCCGAGACCCGGGCTCCGAGAATGAG
TTCGCGGATGACGAGCACAGCACGGTGGAGGAGAGCGAGGGCCGCCGGGACTCCCTCTTCATCCCCATCCGGGCCCGCGAGCGCCGGAGC
AGCTACAGCGGCTACAGCGGCTACAGCCAGGGCAGCCGCTCCTCGCGCATCTTCCCCAGCCTGCGGCGCAGCGTGAAGCGCAACAGCACG
GTGGACTGCAACGGCGTGGTGTCCCTCATCGGCGGCCCCGGCTCCCACATCGGCGGGCGTCTCCTGCCAGAGGCTACAACTGAGGTGGAA
ATTAAGAAGAAAGGCCCTGGATCTCTTTTAGTTTCCATGGACCAATTAGCCTCCTACGGGCGGAAGGACAGAATCAACAGTATAATGAGT
GTTGTTACAAATACACTAGTAGAAGAACTGGAAGAGTCTCAGAGAAAGTGCCCGCCATGCTGGTATAAATTTGCCAACACTTTCCTCATC
TGGGAGTGCCACCCCTACTGGATAAAACTGAAAGAGATTGTGAACTTGATAGTTATGGACCCTTTTGTGGATTTAGCCATCACCATCTGC
ATCGTCCTGAATACACTGTTTATGGCAATGGAGCACCATCCTATGACACCACAATTTGAACATGTCTTGGCTGTAGGAAATCTGGTTTTC
ACTGGAATTTTCACAGCGGAAATGTTCCTGAAGCTCATAGCCATGGATCCCTACTATTATTTCCAAGAAGGTTGGAACATTTTTGACGGA
TTTATTGTCTCCCTCAGTTTAATGGAACTGAGTCTAGCAGACGTGGAGGGGCTTTCAGTGCTGCGATCTTTCCGATTGCTCCGAGTCTTC
AAATTGGCCAAATCCTGGCCCACCCTGAACATGCTAATCAAGATTATTGGAAATTCAGTGGGTGCCCTGGGCAACCTGACACTGGTGCTG
GCCATTATTGTCTTCATCTTTGCCGTGGTGGGGATGCAACTCTTTGGAAAAAGCTACAAAGAGTGTGTCTGCAAGATCAACCAGGACTGT
GAACTCCCTCGCTGGCATATGCATGACTTTTTCCATTCCTTCCTCATTGTCTTTCGAGTGTTGTGCGGGGAGTGGATTGAGACCATGTGG
GACTGCATGGAAGTGGCAGGCCAGGCCATGTGCCTCATTGTCTTTATGATGGTCATGGTGATTGGCAACTTGGTGGTGCTGAACCTGTTT
CTGGCCTTGCTCCTGAGCTCCTTCAGTGCAGACAACCTGGCTGCCACAGATGACGATGGGGAAATGAACAACCTCCAGATCTCAGTGATC
CGTATCAAGAAGGGTGTGGCCTGGACCAAACTAAAGGTGCACGCCTTCATGCAGGCCCACTTTAAGCAGCGTGAGGCTGATGAGGTGAAG
CCTCTGGATGAGTTGTATGAAAAGAAGGCCAACTGTATCGCCAATCACACCGGTGCAGACATCCACCGGAATGGTGACTTCCAGAAGAAT
GGCAATGGCACAACCAGCGGCATTGGCAGCAGCGTGGAGAAGTACATCATTGATGAGGACCACATGTCCTTCATCAACAACCCCAACTTG
ACTGTACGGGTACCCATTGCTGTGGGCGAGTCTGACTTTGAGAACCTCAACACAGAGGATGTTAGCAGCGAGTCGGATCCTGAAGGCAGC
AAAGATAAACTAGATGACACCAGCTCCTCTGAAGGAAGCACCATTGATATCAAACCAGAAGTAGAAGAGGTCCCTGTGGAACAGCCTGAG
GAATACTTGGATCCAGATGCCTGCTTCACAGAAGGTTGTGTCCAGCGGTTCAAGTGCTGCCAGGTCAACATCGAGGAAGGGCTAGGCAAG
TCTTGGTGGATCCTGCGGAAAACCTGCTTCCTCATCGTGGAGCACAACTGGTTTGAGACCTTCATCATCTTCATGATTCTGCTGAGCAGT
GGCGCCCTGGCCTTCGAGGACATCTACATTGAGCAGAGAAAGACCATCCGCACCATCCTGGAATATGCTGACAAAGTCTTCACCTATATC
TTCATCCTGGAGATGTTGCTCAAGTGGACAGCCTATGGCTTCGTCAAGTTCTTCACCAATGCCTGGTGTTGGCTGGACTTCCTCATTGTG
GCTGTGGTGGTGAATGCCTTGGTGGGCGCCATCCCCTCCATCATGAATGTGCTGCTGGTGTGTCTCATCTTCTGGCTGATTTTCAGCATC
ATGGGAGTTAACTTGTTTGCGGGAAAGTACCACTACTGCTTTAATGAGACTTCTGAAATCCGATTTGAAATTGAAGATGTCAACAATAAA
ACTGAATGTGAAAAGCTTATGGAGGGGAACAATACAGAGATCAGATGGAAGAACGTGAAGATCAACTTTGACAATGTTGGGGCAGGATAC
CTGGCCCTTCTTCAAGTAGCAACCTTCAAAGGCTGGATGGACATCATGTATGCAGCTGTAGATTCCCGGAAGCCTGATGAGCAGCCTAAG
TATGAGGACAATATCTACATGTACATCTATTTTGTCATCTTCATCATCTTCGGCTCCTTCTTCACCCTGAACCTGTTCATTGGTGTCATC
ATTGATAACTTCAATCAACAAAAGAAAAAGTTCGGAGGTCAGGACATCTTCATGACCGAAGAACAGAAGAAGTACTACAATGCCATGAAA
AAGCTGGGCTCAAAGAAGCCACAGAAACCTATTCCCCGCCCCTTGGTATCATCTTTATCAGAAAGTGAGGAGTCCCAGGACTCATCCGAC
AGCATAGGCTCCTCACAGAAAGCCCACGGGATCCTAGCACGGCGCCCATCTTACAGAAAAATTTTGAAAGACTTATCTTCTGAAGATACA
CGGGGCAGAAAAGGAGACGGAGAAAATTCTGGAGTTTCTGCTGCTGTCACTTCTATGTCTGTTCCAACTCCCATCTATCAGACTAGCAGC
GGACAGTACATTGCCATTGCCCCAAATGGAGCCTTACAGTTGGCAAGTCCAGGCACAGATGGAGTACAGGGACTTCAGACATTAACCATG
ACAAATTCAGGCAGTACTCAGCAAGGTACAACTATTCTTCAGTATGCACAGACCTCTGATGGACAGCAGATACTTGTGCCCAGCAATCAG
GTGGTCGTACAAACTGCATCAGGAGATATGCAAACATATCAGATCCGAACTACACCTTCAGCTACTTCTCTGCCACAAACTGTGGTGATG
ACATCTCCTGTGACTCTCACCTCTCAGACAACTAAGACAGATGACCCCCAATTGAAAAGAGAAATAAGGTTAATGAAAAACAGAGAAGCT
GCTCGAGAATGTCGCAGAAAGAAGAAAGAATATGTGAAATGCCTGGAAAACCGAGTTGCAGTCCTGGAAAATCAAAATAAAACTCTAATA
GAAGAGTTAAAAACTTTGAAGGATCTTTATTCCAATAAAAGTGTTTGATTCCTAAGAAAGAAAATATTTTTGTGGACATGCATAAAAATT
AAATGGATTTCCTAGTGGAGTTTTATAAATTAAAAGGTCAAAACTGAAGCTTTTTATTTAGGCTTTTCCAAATCAAGGATAAATATCTTA
CGCACGATATCTAGTGACAGAGGAGAAAGTGGAAAATGACCTCAAGGAAGCTACGGGCACAACTGGAAGCTTTGTAGAAATTAAACATAT
TCAAGGAGCAAGAAATGAACTTTCAGCAGTCTAAATTTTCTAAATAACCAATAGTTGCCAATCTAAAATGGCAGAGAAGATGAAATTTGA
TAAACTGAATTTTTTTTAAAAATCCATTTACCCTACAGGTTTGCATTTGTTTGCTGAAATTTACCTTTTTTTAGTTATATATATGTGTGT
GTGTGTGTGTAATTTCTGCCAATAAATTCTAAATTACAAAGGTAAGAGAAAACCTAGTACATTACTAAATATATAAAGTATATGTTCTGA
TTATGTATACTTGTTCTAGTGTCAAGTCTTTTTAAGTGGGTTTTTAAAAGTTTGTTATTGGACTTGAATGGATTTTTGAGACTAGGTTAA
TTATTTTTGAGGTCTTATCCTAAAAGGCATCTAAGGTACATGAATGGAGTATGGTGATTTTATAACATTTTTTATCAGAATGGAAAAAGA
ACTGTTTAAAAGTTTGATACTTTTAAATAGTTGGTTTTTTTGCTTACTCTGGTAATGATTTTCTACAAATACATAATAAATTGTTTTTTT
GAGTCTATATTCTGTATGCAGTTGAATATCCATTACTTATTCTGCTGTGCTTTAATAGAATGGAATGTTTACAGGCCCTTAAAATATTAT
TTTTAAAAAACCTTCTGAAGATACATACCAAAGTTTTTCCAAGAAGATTTTATAATCAATTTAATAATGTAAGGTTTATCAGATTCTATA
ATAGTATAGTTATTAAGGCAATTTTATGTTAGAGACTATTTTGTAATGTAGTGAGTGGTACCTTTATAAGAAAAGTGACTGCCAATATAT
TTTTATAGCTGATCTTTATAAATTCTAATGTTGAGTTTTTAATGATTATTTTAAATGTTTATATAGTTTAGTAAAATTTGCATCTCAAAG
TATCATTTTTATATTATGGGACGTTTTCAGATTGGCTAATATTTGCATTGTAAATTTTGTATGCAGTTTATCTAAAATTCAAAAATACTG
TCAGTACACCAGCGTTTAACATCTATATTCCAATTTGTATACAGTTTAAAATTGTACTGCAAAACTATTGTGTGCTCTTACACAGTATGC

>In-frame_ENST00000545061_ENST00000262053_TCGA-DH-A66G_SCN8A_chr12_52184286_+_ATF1_chr12_51189691_length(amino acids)=1713AA_start in transcript=36_stop in transcript=5177
MLQDEKMAARLLAPPGPDSFKPFTPESLANIERRIAESKLKKPPKADGSHREDDEDSKPKPNSDLEAGKSLPFIYGDIPQGLVAVPLEDF
DPYYLTQKTFVVLNRGKTLFRFSATPALYILSPFNLIRRIAIKILIHSVFSMIIMCTILTNCVFMTFSNPPDWSKNVEYTFTGIYTFESL
VKIIARGFCIDGFTFLRDPWNWLDFSVIMMAYITEFVNLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSV
FALIGLQLFMGNLRNKCVVWPINFNESYLENGTKGFDWEEYINNKTNFYTVPGMLEPLLCGNSSDAGQCPEGYQCMKAGRNPNYGYTSFD
TFSWAFLALFRLMTQDYWENLYQLTLRAAGKTYMIFFVLVIFVGSFYLVNLILAVVAMAYEEQNQATLEEAEQKEAEFKAMLEQLKKQQE
EAQAAAMATSAGTVSEDAIEEEGEEGGGSPRSSSEISKLSSKSAKERRNRRKKRKQKELSEGEEKGDPEKVFKSESEDGMRRKAFRLPDN
RIGRKFSIMNQSLLSIPGSPFLSRHNSKSSIFSFRGPGRFRDPGSENEFADDEHSTVEESEGRRDSLFIPIRARERRSSYSGYSGYSQGS
RSSRIFPSLRRSVKRNSTVDCNGVVSLIGGPGSHIGGRLLPEATTEVEIKKKGPGSLLVSMDQLASYGRKDRINSIMSVVTNTLVEELEE
SQRKCPPCWYKFANTFLIWECHPYWIKLKEIVNLIVMDPFVDLAITICIVLNTLFMAMEHHPMTPQFEHVLAVGNLVFTGIFTAEMFLKL
IAMDPYYYFQEGWNIFDGFIVSLSLMELSLADVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGM
QLFGKSYKECVCKINQDCELPRWHMHDFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLIVFMMVMVIGNLVVLNLFLALLLSSFSADN
LAATDDDGEMNNLQISVIRIKKGVAWTKLKVHAFMQAHFKQREADEVKPLDELYEKKANCIANHTGADIHRNGDFQKNGNGTTSGIGSSV
EKYIIDEDHMSFINNPNLTVRVPIAVGESDFENLNTEDVSSESDPEGSKDKLDDTSSSEGSTIDIKPEVEEVPVEQPEEYLDPDACFTEG
CVQRFKCCQVNIEEGLGKSWWILRKTCFLIVEHNWFETFIIFMILLSSGALAFEDIYIEQRKTIRTILEYADKVFTYIFILEMLLKWTAY
GFVKFFTNAWCWLDFLIVAVVVNALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKYHYCFNETSEIRFEIEDVNNKTECEKLMEGNNT
EIRWKNVKINFDNVGAGYLALLQVATFKGWMDIMYAAVDSRKPDEQPKYEDNIYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFG
GQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLVSSLSESEESQDSSDSIGSSQKAHGILARRPSYRKILKDLSSEDTRGRKGDGENSGV
SAAVTSMSVPTPIYQTSSGQYIAIAPNGALQLASPGTDGVQGLQTLTMTNSGSTQQGTTILQYAQTSDGQQILVPSNQVVVQTASGDMQT
YQIRTTPSATSLPQTVVMTSPVTLTSQTTKTDDPQLKREIRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKTLKDLYSN

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Fusion Gene PPI Analysis for SCN8A-ATF1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SCN8A-ATF1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SCN8A-ATF1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneSCN8AC3281191SCN8A-related epilepsy with encephalopathy16CTD_human;GENOMICS_ENGLAND;UNIPROT
HgeneSCN8AC0014544Epilepsy3CTD_human;GENOMICS_ENGLAND
HgeneSCN8AC0005586Bipolar Disorder2PSYGENET
HgeneSCN8AC0086237Epilepsy, Cryptogenic2CTD_human
HgeneSCN8AC0236018Aura2CTD_human
HgeneSCN8AC0751111Awakening Epilepsy2CTD_human
HgeneSCN8AC3280415COGNITIVE IMPAIRMENT WITH OR WITHOUT CEREBELLAR ATAXIA2CTD_human;GENOMICS_ENGLAND
HgeneSCN8AC4310728SEIZURES, BENIGN FAMILIAL INFANTILE, 52CTD_human;GENOMICS_ENGLAND;UNIPROT
HgeneSCN8AC0004134Ataxia1CTD_human
HgeneSCN8AC0007758Cerebellar Ataxia1CTD_human
HgeneSCN8AC0019372Herpesviridae Infections1CTD_human
HgeneSCN8AC0020796Profound Mental Retardation1CTD_human
HgeneSCN8AC0025363Mental Retardation, Psychosocial1CTD_human
HgeneSCN8AC0027765nervous system disorder1CTD_human
HgeneSCN8AC0032768Postherpetic neuralgia1CTD_human
HgeneSCN8AC0037140B Virus Infection1CTD_human
HgeneSCN8AC0038220Status Epilepticus1CTD_human
HgeneSCN8AC0040822Tremor1CTD_human
HgeneSCN8AC0040827Saturnine Tremor1CTD_human
HgeneSCN8AC0149840Senile Tremor1CTD_human
HgeneSCN8AC0220669Familial benign neonatal epilepsy1ORPHANET
HgeneSCN8AC0234162Cerebellar Dysmetria1CTD_human
HgeneSCN8AC0234357Adiadochokinesis1CTD_human
HgeneSCN8AC0234370Persistent Tremor1CTD_human
HgeneSCN8AC0234371Continuous Tremor1CTD_human
HgeneSCN8AC0234372Intermittent Tremor1CTD_human
HgeneSCN8AC0234373Fine Tremor1CTD_human
HgeneSCN8AC0234374Coarse Tremor1CTD_human
HgeneSCN8AC0234375Massive Tremor1CTD_human
HgeneSCN8AC0234376Action Tremor1CTD_human
HgeneSCN8AC0234377Passive Tremor1CTD_human
HgeneSCN8AC0234378Static Tremor1CTD_human
HgeneSCN8AC0234379Resting Tremor1CTD_human
HgeneSCN8AC0234381Darkness Tremor1CTD_human
HgeneSCN8AC0235078Tremor, Perioral1CTD_human
HgeneSCN8AC0235081Tremor, Limb1CTD_human
HgeneSCN8AC0235082Tremor, Muscle1CTD_human
HgeneSCN8AC0235083Nerve Tremors1CTD_human
HgeneSCN8AC0235843Tremor, Neonatal1CTD_human
HgeneSCN8AC0240991Ataxia, Sensory1CTD_human
HgeneSCN8AC0270823Petit mal status1CTD_human
HgeneSCN8AC0278161Ataxia, Motor1CTD_human
HgeneSCN8AC0311335Grand Mal Status Epilepticus1CTD_human
HgeneSCN8AC0393734Complex Partial Status Epilepticus1CTD_human
HgeneSCN8AC0427190Ataxia, Truncal1CTD_human
HgeneSCN8AC0520966Abnormal coordination1CTD_human
HgeneSCN8AC0750937Ataxia, Appendicular1CTD_human
HgeneSCN8AC0750940Tremor, Rubral1CTD_human
HgeneSCN8AC0750994Cerebellar Hemiataxia1CTD_human
HgeneSCN8AC0751522Status Epilepticus, Subclinical1CTD_human
HgeneSCN8AC0751523Non-Convulsive Status Epilepticus1CTD_human
HgeneSCN8AC0751524Simple Partial Status Epilepticus1CTD_human
HgeneSCN8AC0751564Pill Rolling Tremor1CTD_human
HgeneSCN8AC0751565Tremor, Semirhythmic1CTD_human
HgeneSCN8AC0917816Mental deficiency1CTD_human
HgeneSCN8AC1527384Involuntary Quiver1CTD_human
HgeneSCN8AC1535926Neurodevelopmental Disorders1CTD_human
HgeneSCN8AC1865926Infantile convulsions and paroxysmal choreoathetosis, familial (disorder)1ORPHANET
HgeneSCN8AC3668822Hypermetria (finding)1CTD_human
HgeneSCN8AC3714756Intellectual Disability1CTD_human;GENOMICS_ENGLAND
TgeneATF1C0032460Polycystic Ovary Syndrome1CTD_human
TgeneATF1C0206651Clear Cell Sarcoma of Soft Tissue1ORPHANET
TgeneATF1C1136382Sclerocystic Ovaries1CTD_human