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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SCNN1A-TNFRSF1A (FusionGDB2 ID:79220)

Fusion Gene Summary for SCNN1A-TNFRSF1A

check button Fusion gene summary
Fusion gene informationFusion gene name: SCNN1A-TNFRSF1A
Fusion gene ID: 79220
HgeneTgene
Gene symbol

SCNN1A

TNFRSF1A

Gene ID

6337

7132

Gene namesodium channel epithelial 1 subunit alphaTNF receptor superfamily member 1A
SynonymsBESC2|ENaCa|ENaCalpha|LIDLS3|SCNEA|SCNN1CD120a|FPF|TBP1|TNF-R|TNF-R-I|TNF-R55|TNFAR|TNFR1|TNFR55|TNFR60|p55|p55-R|p60
Cytomap

12p13.31

12p13.31

Type of geneprotein-codingprotein-coding
Descriptionamiloride-sensitive sodium channel subunit alphaalpha ENaC-2alpha-ENaCalpha-NaCHamiloride-sensitive epithelial sodium channel alpha subunitamiloride-sensitive sodium channel subunit alpha 2epithelial Na(+) channel subunit alphanasal epithelial soditumor necrosis factor receptor superfamily member 1ATNF-R1TNF-RITNFR-Itumor necrosis factor binding protein 1tumor necrosis factor receptor 1A isoform betatumor necrosis factor receptor type 1tumor necrosis factor-alpha receptor
Modification date2020031320200322
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000360168, ENST00000358945, 
ENST00000540037, ENST00000228916, 
ENST00000396966, ENST00000543768, 
ENST00000538979, 		ENST00000162749, 
ENST00000540022, ENST00000366159, 
ENST00000437813, 
Fusion gene scores* DoF score3 X 4 X 3=3613 X 13 X 3=507
# samples 615
** MAII scorelog2(6/36*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(15/507*10)=-1.75702324650746
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SCNN1A [Title/Abstract] AND TNFRSF1A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSCNN1A(6457893)-TNFRSF1A(6443410), # samples:1
SCNN1A(6457237)-TNFRSF1A(6443410), # samples:1
TNFRSF1A(6442903)-SCNN1A(6465046), # samples:2
Anticipated loss of major functional domain due to fusion event.SCNN1A-TNFRSF1A seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
SCNN1A-TNFRSF1A seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
TNFRSF1A-SCNN1A seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
TNFRSF1A-SCNN1A seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSCNN1A

GO:0035725

sodium ion transmembrane transport

24124190

HgeneSCNN1A

GO:0050891

multicellular organismal water homeostasis

24124190

HgeneSCNN1A

GO:0055078

sodium ion homeostasis

24124190


check buttonFusion gene breakpoints across SCNN1A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across TNFRSF1A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/AJA757711SCNN1Achr12

6457893

-TNFRSF1Achr12

6443410

-
ChiTaRS5.0N/AJA757713SCNN1Achr12

6457237

-TNFRSF1Achr12

6443410

-


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Fusion Gene ORF analysis for SCNN1A-TNFRSF1A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000360168ENST00000162749SCNN1Achr12

6457893

-TNFRSF1Achr12

6443410

-
In-frameENST00000360168ENST00000540022SCNN1Achr12

6457893

-TNFRSF1Achr12

6443410

-
In-frameENST00000360168ENST00000366159SCNN1Achr12

6457893

-TNFRSF1Achr12

6443410

-
In-frameENST00000360168ENST00000437813SCNN1Achr12

6457893

-TNFRSF1Achr12

6443410

-
In-frameENST00000358945ENST00000162749SCNN1Achr12

6457893

-TNFRSF1Achr12

6443410

-
In-frameENST00000358945ENST00000540022SCNN1Achr12

6457893

-TNFRSF1Achr12

6443410

-
In-frameENST00000358945ENST00000366159SCNN1Achr12

6457893

-TNFRSF1Achr12

6443410

-
In-frameENST00000358945ENST00000437813SCNN1Achr12

6457893

-TNFRSF1Achr12

6443410

-
Frame-shiftENST00000540037ENST00000162749SCNN1Achr12

6457893

-TNFRSF1Achr12

6443410

-
Frame-shiftENST00000540037ENST00000540022SCNN1Achr12

6457893

-TNFRSF1Achr12

6443410

-
Frame-shiftENST00000540037ENST00000366159SCNN1Achr12

6457893

-TNFRSF1Achr12

6443410

-
Frame-shiftENST00000540037ENST00000437813SCNN1Achr12

6457893

-TNFRSF1Achr12

6443410

-
Frame-shiftENST00000228916ENST00000162749SCNN1Achr12

6457893

-TNFRSF1Achr12

6443410

-
Frame-shiftENST00000228916ENST00000540022SCNN1Achr12

6457893

-TNFRSF1Achr12

6443410

-
Frame-shiftENST00000228916ENST00000366159SCNN1Achr12

6457893

-TNFRSF1Achr12

6443410

-
Frame-shiftENST00000228916ENST00000437813SCNN1Achr12

6457893

-TNFRSF1Achr12

6443410

-
3UTR-3CDSENST00000396966ENST00000162749SCNN1Achr12

6457893

-TNFRSF1Achr12

6443410

-
3UTR-3CDSENST00000396966ENST00000540022SCNN1Achr12

6457893

-TNFRSF1Achr12

6443410

-
3UTR-3CDSENST00000396966ENST00000366159SCNN1Achr12

6457893

-TNFRSF1Achr12

6443410

-
3UTR-3CDSENST00000396966ENST00000437813SCNN1Achr12

6457893

-TNFRSF1Achr12

6443410

-
In-frameENST00000543768ENST00000162749SCNN1Achr12

6457893

-TNFRSF1Achr12

6443410

-
In-frameENST00000543768ENST00000540022SCNN1Achr12

6457893

-TNFRSF1Achr12

6443410

-
In-frameENST00000543768ENST00000366159SCNN1Achr12

6457893

-TNFRSF1Achr12

6443410

-
In-frameENST00000543768ENST00000437813SCNN1Achr12

6457893

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000538979ENST00000162749SCNN1Achr12

6457893

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000538979ENST00000540022SCNN1Achr12

6457893

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000538979ENST00000366159SCNN1Achr12

6457893

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000538979ENST00000437813SCNN1Achr12

6457893

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000360168ENST00000162749SCNN1Achr12

6457237

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000360168ENST00000540022SCNN1Achr12

6457237

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000360168ENST00000366159SCNN1Achr12

6457237

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000360168ENST00000437813SCNN1Achr12

6457237

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000358945ENST00000162749SCNN1Achr12

6457237

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000358945ENST00000540022SCNN1Achr12

6457237

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000358945ENST00000366159SCNN1Achr12

6457237

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000358945ENST00000437813SCNN1Achr12

6457237

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000540037ENST00000162749SCNN1Achr12

6457237

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000540037ENST00000540022SCNN1Achr12

6457237

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000540037ENST00000366159SCNN1Achr12

6457237

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000540037ENST00000437813SCNN1Achr12

6457237

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000228916ENST00000162749SCNN1Achr12

6457237

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000228916ENST00000540022SCNN1Achr12

6457237

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000228916ENST00000366159SCNN1Achr12

6457237

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000228916ENST00000437813SCNN1Achr12

6457237

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000396966ENST00000162749SCNN1Achr12

6457237

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000396966ENST00000540022SCNN1Achr12

6457237

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000396966ENST00000366159SCNN1Achr12

6457237

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000396966ENST00000437813SCNN1Achr12

6457237

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000543768ENST00000162749SCNN1Achr12

6457237

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000543768ENST00000540022SCNN1Achr12

6457237

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000543768ENST00000366159SCNN1Achr12

6457237

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000543768ENST00000437813SCNN1Achr12

6457237

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000538979ENST00000162749SCNN1Achr12

6457237

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000538979ENST00000540022SCNN1Achr12

6457237

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000538979ENST00000366159SCNN1Achr12

6457237

-TNFRSF1Achr12

6443410

-
intron-3CDSENST00000538979ENST00000437813SCNN1Achr12

6457237

-TNFRSF1Achr12

6443410

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

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Fusion Genomic Features for SCNN1A-TNFRSF1A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SCNN1A-TNFRSF1A


check button Go to

FGviewer for the breakpoints of chr12:6457893-chr12:6443410

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSCNN1Achr12:6457893chr12:6443410ENST00000228916-12131_85543.0670.0Topological domainCytoplasmic
HgeneSCNN1Achr12:6457893chr12:6443410ENST00000360168-1112107_562602.0729.0Topological domainExtracellular
HgeneSCNN1Achr12:6457893chr12:6443410ENST00000360168-11121_85602.0729.0Topological domainCytoplasmic
HgeneSCNN1Achr12:6457893chr12:6443410ENST00000543768-1213107_562566.0693.0Topological domainExtracellular
HgeneSCNN1Achr12:6457893chr12:6443410ENST00000543768-12131_85566.0693.0Topological domainCytoplasmic
HgeneSCNN1Achr12:6457893chr12:6443410ENST00000228916-121386_106543.0670.0TransmembraneHelical%3B Name%3D1
HgeneSCNN1Achr12:6457893chr12:6443410ENST00000360168-1112563_583602.0729.0TransmembraneHelical%3B Name%3D2
HgeneSCNN1Achr12:6457893chr12:6443410ENST00000360168-111286_106602.0729.0TransmembraneHelical%3B Name%3D1
HgeneSCNN1Achr12:6457893chr12:6443410ENST00000543768-121386_106566.0693.0TransmembraneHelical%3B Name%3D1
TgeneTNFRSF1Achr12:6457893chr12:6443410ENST00000162749010356_44113.0456.0DomainDeath
TgeneTNFRSF1Achr12:6457893chr12:6443410ENST0000036615906356_44113.0219.0DomainDeath
TgeneTNFRSF1Achr12:6457893chr12:6443410ENST00000162749010338_34813.0456.0RegionNote=N-SMase activation domain (NSD)
TgeneTNFRSF1Achr12:6457893chr12:6443410ENST0000036615906338_34813.0219.0RegionNote=N-SMase activation domain (NSD)
TgeneTNFRSF1Achr12:6457893chr12:6443410ENST00000162749010126_16613.0456.0RepeatNote=TNFR-Cys 3
TgeneTNFRSF1Achr12:6457893chr12:6443410ENST00000162749010167_19613.0456.0RepeatNote=TNFR-Cys 4
TgeneTNFRSF1Achr12:6457893chr12:6443410ENST0000016274901043_8213.0456.0RepeatNote=TNFR-Cys 1
TgeneTNFRSF1Achr12:6457893chr12:6443410ENST0000016274901083_12513.0456.0RepeatNote=TNFR-Cys 2
TgeneTNFRSF1Achr12:6457893chr12:6443410ENST0000036615906126_16613.0219.0RepeatNote=TNFR-Cys 3
TgeneTNFRSF1Achr12:6457893chr12:6443410ENST0000036615906167_19613.0219.0RepeatNote=TNFR-Cys 4
TgeneTNFRSF1Achr12:6457893chr12:6443410ENST000003661590643_8213.0219.0RepeatNote=TNFR-Cys 1
TgeneTNFRSF1Achr12:6457893chr12:6443410ENST000003661590683_12513.0219.0RepeatNote=TNFR-Cys 2
TgeneTNFRSF1Achr12:6457893chr12:6443410ENST00000162749010233_45513.0456.0Topological domainCytoplasmic
TgeneTNFRSF1Achr12:6457893chr12:6443410ENST0000016274901030_21113.0456.0Topological domainExtracellular
TgeneTNFRSF1Achr12:6457893chr12:6443410ENST0000036615906233_45513.0219.0Topological domainCytoplasmic
TgeneTNFRSF1Achr12:6457893chr12:6443410ENST000003661590630_21113.0219.0Topological domainExtracellular
TgeneTNFRSF1Achr12:6457893chr12:6443410ENST00000162749010212_23213.0456.0TransmembraneHelical
TgeneTNFRSF1Achr12:6457893chr12:6443410ENST0000036615906212_23213.0219.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSCNN1Achr12:6457893chr12:6443410ENST00000228916-1213107_562543.0670.0Topological domainExtracellular
HgeneSCNN1Achr12:6457893chr12:6443410ENST00000228916-1213584_669543.0670.0Topological domainCytoplasmic
HgeneSCNN1Achr12:6457893chr12:6443410ENST00000360168-1112584_669602.0729.0Topological domainCytoplasmic
HgeneSCNN1Achr12:6457893chr12:6443410ENST00000543768-1213584_669566.0693.0Topological domainCytoplasmic
HgeneSCNN1Achr12:6457893chr12:6443410ENST00000228916-1213563_583543.0670.0TransmembraneHelical%3B Name%3D2
HgeneSCNN1Achr12:6457893chr12:6443410ENST00000543768-1213563_583566.0693.0TransmembraneHelical%3B Name%3D2


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Fusion Gene Sequence for SCNN1A-TNFRSF1A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for SCNN1A-TNFRSF1A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SCNN1A-TNFRSF1A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SCNN1A-TNFRSF1A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneSCNN1AC1449843Pseudohypoaldosteronism, Type I, Autosomal Recessive7CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
HgeneSCNN1AC0010674Cystic Fibrosis2CTD_human
HgeneSCNN1AC0020538Hypertensive disease2CTD_human
HgeneSCNN1AC0024115Lung diseases2CTD_human;GENOMICS_ENGLAND
HgeneSCNN1AC0221043Liddle Syndrome2CTD_human;ORPHANET
HgeneSCNN1AC0392164Pulmonary Cystic Fibrosis2CTD_human
HgeneSCNN1AC1527396Fibrocystic Disease of Pancreas2CTD_human
HgeneSCNN1AC2751666BRONCHIECTASIS WITH OR WITHOUT ELEVATED SWEAT CHLORIDE 22CTD_human;GENOMICS_ENGLAND;UNIPROT
HgeneSCNN1AC4748292LIDDLE SYNDROME 32GENOMICS_ENGLAND;UNIPROT
HgeneSCNN1AC0027654Embryonal Neoplasm1CTD_human
HgeneSCNN1AC0027658Neoplasms, Germ Cell and Embryonal1CTD_human
HgeneSCNN1AC0032460Polycystic Ovary Syndrome1CTD_human
HgeneSCNN1AC0032914Pre-Eclampsia1CTD_human
HgeneSCNN1AC0033687Proteinuria1CTD_human
HgeneSCNN1AC0033805Pseudohypoaldosteronism1CTD_human
HgeneSCNN1AC0205851Germ cell tumor1CTD_human
HgeneSCNN1AC0205852Neoplasms, Embryonal and Mixed1CTD_human
HgeneSCNN1AC0268436Pseudohypoaldosteronism, Type I1CTD_human
HgeneSCNN1AC0339985Idiopathic bronchiectasis1ORPHANET
HgeneSCNN1AC0740345Germ Cell Cancer1CTD_human
HgeneSCNN1AC0751364Cancer, Embryonal1CTD_human
HgeneSCNN1AC0751365Cancer, Embryonal and Mixed1CTD_human
HgeneSCNN1AC1136382Sclerocystic Ovaries1CTD_human
HgeneSCNN1AC1449842Pseudohypoaldosteronism, Type I, Autosomal Dominant1CTD_human
HgeneSCNN1AC1449844Pseudohypoaldosteronism, Type II1CTD_human
HgeneSCNN1AC2713447Hyperpotassemia and Hypertension, Familial1CTD_human
TgeneTNFRSF1AC1275126TNF receptor-associated periodic fever syndrome (TRAPS)7CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneTNFRSF1AC0011570Mental Depression5PSYGENET
TgeneTNFRSF1AC0011581Depressive disorder5PSYGENET
TgeneTNFRSF1AC0026769Multiple Sclerosis2CTD_human
TgeneTNFRSF1AC0751324Multiple Sclerosis, Acute Fulminating2CTD_human
TgeneTNFRSF1AC0002152Alloxan Diabetes1CTD_human
TgeneTNFRSF1AC0003123Anorexia1CTD_human
TgeneTNFRSF1AC0004364Autoimmune Diseases1CTD_human
TgeneTNFRSF1AC0006625Cachexia1CTD_human
TgeneTNFRSF1AC0007786Brain Ischemia1CTD_human
TgeneTNFRSF1AC0008312Primary biliary cirrhosis1CTD_human
TgeneTNFRSF1AC0010674Cystic Fibrosis1CTD_human
TgeneTNFRSF1AC0011853Diabetes Mellitus, Experimental1CTD_human
TgeneTNFRSF1AC0011860Diabetes Mellitus, Non-Insulin-Dependent1CTD_human
TgeneTNFRSF1AC0015967Fever1CTD_human
TgeneTNFRSF1AC0018801Heart failure1CTD_human
TgeneTNFRSF1AC0018802Congestive heart failure1CTD_human
TgeneTNFRSF1AC0020517Hypersensitivity1CTD_human
TgeneTNFRSF1AC0023212Left-Sided Heart Failure1CTD_human
TgeneTNFRSF1AC0023892Biliary cirrhosis1CTD_human
TgeneTNFRSF1AC0032285Pneumonia1CTD_human
TgeneTNFRSF1AC0032300Lobar Pneumonia1CTD_human
TgeneTNFRSF1AC0036341Schizophrenia1PSYGENET
TgeneTNFRSF1AC0038433Streptozotocin Diabetes1CTD_human
TgeneTNFRSF1AC0149910Intermittent joint effusion1ORPHANET
TgeneTNFRSF1AC0235527Heart Failure, Right-Sided1CTD_human
TgeneTNFRSF1AC0238065Secondary Biliary Cholangitis1CTD_human
TgeneTNFRSF1AC0242706Hyperoxia1CTD_human
TgeneTNFRSF1AC0273115Lung Injury1CTD_human
TgeneTNFRSF1AC0392164Pulmonary Cystic Fibrosis1CTD_human
TgeneTNFRSF1AC0751422Hereditary Autoinflammatory Diseases1GENOMICS_ENGLAND
TgeneTNFRSF1AC0887898Experimental Lung Inflammation1CTD_human
TgeneTNFRSF1AC0917798Cerebral Ischemia1CTD_human
TgeneTNFRSF1AC1527304Allergic Reaction1CTD_human
TgeneTNFRSF1AC1527396Fibrocystic Disease of Pancreas1CTD_human
TgeneTNFRSF1AC1959583Myocardial Failure1CTD_human
TgeneTNFRSF1AC1961112Heart Decompensation1CTD_human
TgeneTNFRSF1AC2350344Chronic Lung Injury1CTD_human
TgeneTNFRSF1AC3714636Pneumonitis1CTD_human
TgeneTNFRSF1AC3860213Autoinflammatory disorder1GENOMICS_ENGLAND
TgeneTNFRSF1AC4551595Biliary Cirrhosis, Primary, 11CTD_human