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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SCUBE2-LDHC (FusionGDB2 ID:79264)

Fusion Gene Summary for SCUBE2-LDHC

check button Fusion gene summary
Fusion gene informationFusion gene name: SCUBE2-LDHC
Fusion gene ID: 79264
HgeneTgene
Gene symbol

SCUBE2

LDHC

Gene ID

57758

3948

Gene namesignal peptide, CUB domain and EGF like domain containing 2lactate dehydrogenase C
SynonymsCEGB1|CEGF1|CEGP1|scube/YouCT32|LDH3|LDHX
Cytomap

11p15.4

11p15.1

Type of geneprotein-codingprotein-coding
Descriptionsignal peptide, CUB and EGF-like domain-containing protein 2L-lactate dehydrogenase C chainLDH testis subunitLDH-CLDH-Xcancer/testis antigen 32lactate dehydrogenase C4lactate dehydrogenase c variant 1lactate dehydrogenase c variant 3lactate dehydrogenase c variant 4lactate dehydrogenase c variant 5testis
Modification date2020031320200313
UniProtAcc.

P07864

Ensembl transtripts involved in fusion geneENST00000457346, ENST00000309263, 
ENST00000450649, ENST00000520467, 
ENST00000534295, 		ENST00000541669, 
ENST00000280704, ENST00000544105, 
ENST00000536880, ENST00000535809, 
ENST00000537486, ENST00000546146, 
Fusion gene scores* DoF score6 X 6 X 4=1443 X 3 X 2=18
# samples 63
** MAII scorelog2(6/144*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: SCUBE2 [Title/Abstract] AND LDHC [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSCUBE2(9090917)-LDHC(18451284), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across SCUBE2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across LDHC (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-FD-A5BV-01ASCUBE2chr11

9090917

-LDHCchr11

18451284

+
ChimerDB4BLCATCGA-FD-A5BV-01ASCUBE2chr11

9090917

-LDHCchr11

18451284

+
ChimerDB4BLCATCGA-FD-A5BV-01ASCUBE2chr11

9090917

-LDHCchr11

18451284

+


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Fusion Gene ORF analysis for SCUBE2-LDHC

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000457346ENST00000541669SCUBE2chr11

9090917

-LDHCchr11

18451284

+
In-frameENST00000457346ENST00000280704SCUBE2chr11

9090917

-LDHCchr11

18451284

+
In-frameENST00000457346ENST00000544105SCUBE2chr11

9090917

-LDHCchr11

18451284

+
5CDS-intronENST00000457346ENST00000536880SCUBE2chr11

9090917

-LDHCchr11

18451284

+
5CDS-intronENST00000457346ENST00000535809SCUBE2chr11

9090917

-LDHCchr11

18451284

+
5CDS-intronENST00000457346ENST00000537486SCUBE2chr11

9090917

-LDHCchr11

18451284

+
5CDS-intronENST00000457346ENST00000546146SCUBE2chr11

9090917

-LDHCchr11

18451284

+
In-frameENST00000309263ENST00000541669SCUBE2chr11

9090917

-LDHCchr11

18451284

+
In-frameENST00000309263ENST00000280704SCUBE2chr11

9090917

-LDHCchr11

18451284

+
In-frameENST00000309263ENST00000544105SCUBE2chr11

9090917

-LDHCchr11

18451284

+
5CDS-intronENST00000309263ENST00000536880SCUBE2chr11

9090917

-LDHCchr11

18451284

+
5CDS-intronENST00000309263ENST00000535809SCUBE2chr11

9090917

-LDHCchr11

18451284

+
5CDS-intronENST00000309263ENST00000537486SCUBE2chr11

9090917

-LDHCchr11

18451284

+
5CDS-intronENST00000309263ENST00000546146SCUBE2chr11

9090917

-LDHCchr11

18451284

+
In-frameENST00000450649ENST00000541669SCUBE2chr11

9090917

-LDHCchr11

18451284

+
In-frameENST00000450649ENST00000280704SCUBE2chr11

9090917

-LDHCchr11

18451284

+
In-frameENST00000450649ENST00000544105SCUBE2chr11

9090917

-LDHCchr11

18451284

+
5CDS-intronENST00000450649ENST00000536880SCUBE2chr11

9090917

-LDHCchr11

18451284

+
5CDS-intronENST00000450649ENST00000535809SCUBE2chr11

9090917

-LDHCchr11

18451284

+
5CDS-intronENST00000450649ENST00000537486SCUBE2chr11

9090917

-LDHCchr11

18451284

+
5CDS-intronENST00000450649ENST00000546146SCUBE2chr11

9090917

-LDHCchr11

18451284

+
In-frameENST00000520467ENST00000541669SCUBE2chr11

9090917

-LDHCchr11

18451284

+
In-frameENST00000520467ENST00000280704SCUBE2chr11

9090917

-LDHCchr11

18451284

+
In-frameENST00000520467ENST00000544105SCUBE2chr11

9090917

-LDHCchr11

18451284

+
5CDS-intronENST00000520467ENST00000536880SCUBE2chr11

9090917

-LDHCchr11

18451284

+
5CDS-intronENST00000520467ENST00000535809SCUBE2chr11

9090917

-LDHCchr11

18451284

+
5CDS-intronENST00000520467ENST00000537486SCUBE2chr11

9090917

-LDHCchr11

18451284

+
5CDS-intronENST00000520467ENST00000546146SCUBE2chr11

9090917

-LDHCchr11

18451284

+
intron-3CDSENST00000534295ENST00000541669SCUBE2chr11

9090917

-LDHCchr11

18451284

+
intron-3CDSENST00000534295ENST00000280704SCUBE2chr11

9090917

-LDHCchr11

18451284

+
intron-3CDSENST00000534295ENST00000544105SCUBE2chr11

9090917

-LDHCchr11

18451284

+
intron-intronENST00000534295ENST00000536880SCUBE2chr11

9090917

-LDHCchr11

18451284

+
intron-intronENST00000534295ENST00000535809SCUBE2chr11

9090917

-LDHCchr11

18451284

+
intron-intronENST00000534295ENST00000537486SCUBE2chr11

9090917

-LDHCchr11

18451284

+
intron-intronENST00000534295ENST00000546146SCUBE2chr11

9090917

-LDHCchr11

18451284

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000457346SCUBE2chr119090917-ENST00000541669LDHCchr1118451284+2404718511472473
ENST00000457346SCUBE2chr119090917-ENST00000280704LDHCchr1118451284+1589718511472473
ENST00000457346SCUBE2chr119090917-ENST00000544105LDHCchr1118451284+1349718511199382
ENST00000309263SCUBE2chr119090917-ENST00000541669LDHCchr1118451284+2402716491470473
ENST00000309263SCUBE2chr119090917-ENST00000280704LDHCchr1118451284+1587716491470473
ENST00000309263SCUBE2chr119090917-ENST00000544105LDHCchr1118451284+1347716491197382
ENST00000450649SCUBE2chr119090917-ENST00000541669LDHCchr1118451284+2347661181415465
ENST00000450649SCUBE2chr119090917-ENST00000280704LDHCchr1118451284+1532661181415465
ENST00000450649SCUBE2chr119090917-ENST00000544105LDHCchr1118451284+1292661181142374
ENST00000520467SCUBE2chr119090917-ENST00000541669LDHCchr1118451284+2400714471468473
ENST00000520467SCUBE2chr119090917-ENST00000280704LDHCchr1118451284+1585714471468473
ENST00000520467SCUBE2chr119090917-ENST00000544105LDHCchr1118451284+1345714471195382

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000457346ENST00000541669SCUBE2chr119090917-LDHCchr1118451284+0.000680820.9993192
ENST00000457346ENST00000280704SCUBE2chr119090917-LDHCchr1118451284+0.0017424610.9982576
ENST00000457346ENST00000544105SCUBE2chr119090917-LDHCchr1118451284+0.004451610.99554837
ENST00000309263ENST00000541669SCUBE2chr119090917-LDHCchr1118451284+0.0006867570.99931324
ENST00000309263ENST00000280704SCUBE2chr119090917-LDHCchr1118451284+0.0017878770.9982121
ENST00000309263ENST00000544105SCUBE2chr119090917-LDHCchr1118451284+0.0045608250.99543923
ENST00000450649ENST00000541669SCUBE2chr119090917-LDHCchr1118451284+0.0005711860.9994288
ENST00000450649ENST00000280704SCUBE2chr119090917-LDHCchr1118451284+0.0015804360.9984195
ENST00000450649ENST00000544105SCUBE2chr119090917-LDHCchr1118451284+0.004658280.9953418
ENST00000520467ENST00000541669SCUBE2chr119090917-LDHCchr1118451284+0.000700480.9992995
ENST00000520467ENST00000280704SCUBE2chr119090917-LDHCchr1118451284+0.0018779050.99812204
ENST00000520467ENST00000544105SCUBE2chr119090917-LDHCchr1118451284+0.0046094280.99539053

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Fusion Genomic Features for SCUBE2-LDHC


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SCUBE2chr119090916-LDHCchr1118451283+0.0134248310.9865752
SCUBE2chr119090916-LDHCchr1118451283+0.0134248310.9865752

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SCUBE2-LDHC


check button Go to

FGviewer for the breakpoints of chr11:9090917-chr11:18451284

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.LDHC

P07864

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Possible role in sperm motility.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000309263-522128_168214.333333333333341000.0DomainEGF-like 3%3B calcium-binding
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000309263-522177_213214.333333333333341000.0DomainEGF-like 4
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000309263-52245_85214.333333333333341000.0DomainEGF-like 1%3B calcium-binding
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000309263-52286_127214.333333333333341000.0DomainEGF-like 2%3B calcium-binding
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000450649-518128_168214.33333333333334808.0DomainEGF-like 3%3B calcium-binding
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000450649-518177_213214.33333333333334808.0DomainEGF-like 4
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000450649-51845_85214.33333333333334808.0DomainEGF-like 1%3B calcium-binding
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000450649-51886_127214.33333333333334808.0DomainEGF-like 2%3B calcium-binding
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000520467-522128_168214.33333333333334972.0DomainEGF-like 3%3B calcium-binding
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000520467-522177_213214.33333333333334972.0DomainEGF-like 4
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000520467-52245_85214.33333333333334972.0DomainEGF-like 1%3B calcium-binding
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000520467-52286_127214.33333333333334972.0DomainEGF-like 2%3B calcium-binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000309263-522217_252214.333333333333341000.0DomainEGF-like 5
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000309263-522286_321214.333333333333341000.0DomainEGF-like 6
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000309263-522323_363214.333333333333341000.0DomainEGF-like 7%3B calcium-binding
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000309263-522364_402214.333333333333341000.0DomainEGF-like 8%3B calcium-binding
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000309263-522403_443214.333333333333341000.0DomainEGF-like 9%3B calcium-binding
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000309263-522809_921214.333333333333341000.0DomainCUB
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000450649-518217_252214.33333333333334808.0DomainEGF-like 5
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000450649-518286_321214.33333333333334808.0DomainEGF-like 6
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000450649-518323_363214.33333333333334808.0DomainEGF-like 7%3B calcium-binding
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000450649-518364_402214.33333333333334808.0DomainEGF-like 8%3B calcium-binding
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000450649-518403_443214.33333333333334808.0DomainEGF-like 9%3B calcium-binding
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000450649-518809_921214.33333333333334808.0DomainCUB
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000520467-522217_252214.33333333333334972.0DomainEGF-like 5
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000520467-522286_321214.33333333333334972.0DomainEGF-like 6
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000520467-522323_363214.33333333333334972.0DomainEGF-like 7%3B calcium-binding
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000520467-522364_402214.33333333333334972.0DomainEGF-like 8%3B calcium-binding
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000520467-522403_443214.33333333333334972.0DomainEGF-like 9%3B calcium-binding
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000520467-522809_921214.33333333333334972.0DomainCUB
TgeneLDHCchr11:9090917chr11:18451284ENST000002807042829_5781.33333333333333333.0Nucleotide bindingNAD
TgeneLDHCchr11:9090917chr11:18451284ENST000005416692829_5781.33333333333333333.0Nucleotide bindingNAD


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Fusion Gene Sequence for SCUBE2-LDHC


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000457346_ENST00000541669_TCGA-FD-A5BV-01A_SCUBE2_chr11_9090917_-_LDHC_chr11_18451284_length(transcript)=2404nt_BP=718nt
CCGCGCACACCTCCCCGCGCCGCCGCCGCCACCGCCCGCACTCCGCCGCCTCTGCCCGCAACCGCTGAGCCATCCATGGGGGTCGCGGGC
CGCAACCGTCCCGGGGCGGCCTGGGCGGTGCTGCTGCTGCTGCTGCTGCTGCCGCCACTGCTGCTGCTGGCGGGGGCCGTCCCGCCGGGT
CGGGGCCGTGCCGCGGGGCCGCAGGAGGATGTAGATGAGTGTGCCCAAGGGCTAGATGACTGCCATGCCGACGCCCTGTGTCAGAACACA
CCCACCTCCTACAAGTGCTCCTGCAAGCCTGGCTACCAAGGGGAAGGCAGGCAGTGTGAGGACATCGATGAATGTGGAAATGAGCTCAAT
GGAGGCTGTGTCCATGACTGTTTGAATATTCCAGGCAATTATCGTTGCACTTGTTTTGATGGCTTCATGTTGGCTCATGACGGTCATAAT
TGTCTTGATGTGGACGAGTGCCTGGAGAACAATGGCGGCTGCCAGCATACCTGTGTCAACGTCATGGGGAGCTATGAGTGCTGCTGCAAG
GAGGGGTTTTTCCTGAGTGACAATCAGCACACCTGCATTCACCGCTCGGAAGAGGGCCTGAGCTGCATGAATAAGGATCACGGCTGTAGT
CACATCTGCAAGGAGGCCCCAAGGGGCAGCGTCGCCTGTGAGTGCAGGCCTGGTTTTGAGCTGGCCAAGAACCAGAGAGACTGCATCTAT
TACAGTGTATCTGCAAACTCCAGAATAGTTATTGTCACAGCAGGTGCAAGGCAGCAGGAGGGAGAAACTCGCCTTGCCCTGGTCCAACGT
AATGTGGCTATAATGAAATCAATCATTCCTGCCATAGTCCATTATAGTCCTGATTGTAAAATTCTTGTTGTTTCAAATCCAGTGGATATT
TTGACATATATAGTCTGGAAGATAAGTGGCTTACCTGTAACTCGTGTAATTGGAAGTGGTTGTAATCTAGACTCTGCCCGTTTCCGTTAC
CTAATTGGAGAAAAGTTGGGTGTCCACCCCACAAGCTGCCATGGTTGGATTATTGGAGAACATGGTGATTCTAGTGTGCCCTTATGGAGT
GGGGTGAATGTTGCTGGTGTTGCTCTGAAGACTCTGGACCCTAAATTAGGAACGGATTCAGATAAGGAACACTGGAAAAATATCCATAAA
CAAGTTATTCAAAGTGCCTATGAAATTATCAAGCTGAAGGGGTATACCTCTTGGGCTATTGGACTGTCTGTGATGGATTTGGTAGGATCC
ATTTTGAAAAATCTTAGGAGAGTGCACCCAGTTTCCACCATGGTTAAGGGATTATATGGAATAAAAGAAGAACTCTTTCTCAGTATCCCT
TGTGTCTTGGGGCGGAATGGTGTCTCAGATGTTGTGAAAATTAACTTGAATTCTGAGGAGGAGGCCCTTTTCAAGAAGAGTGCAGAAACA
CTTTGGAATATTCAAAAGGATCTAATATTTTAAATTAAAGCCTTCTAATGTTCCACTGTTTGGAGAACAGAAGATAGCAGGCTGTGTATT
TTAAATTTTGAAAGTATTTTCATTTGATCTTTAAAAAATAAAAACAAATTGGAGACCTGTGACATAACTCTAGTCTCTCAAGATTAGAAC
GAGCAAATGGTAAAGAGATTTTCCTCTTTAAGAATCATTTATAGCTCTATTCTAATGATACCCAATCTGTACAGGTGTAAGTTATACTTC
TGAGGTATGTCACATATGTTAGAGTGCCTTCAGATGTAGTAGAATATGTATAATCACTATAATACAGAGCTTTGATTCTTTTCACAAACC
AAGCCCTTTTTCTAGTATTACAATTTTATCTTGTACTTTCATCCGTTAGAGTACCAGCATATTCACTTCATTACATTAGCGTCATATGTT
TATGTATAATCATTATAAATGTGGCCGGGCACTGCAGCCTGGGTGAAAGAGTGAGGCTCTGTCTCAAAAAAAATCATTATAAATGCTTAT
TTTTAAGACCATATATATCAAAAAGAAATAAAAAGCTGAGTGCTGTGGCTCATGGCTGTAATCCCAGTGCTTTGGGAGGGTGAGGCAAGA
GGATCACATGAGTCCAGGAGTTTGAGACCAGCCTTGGCAACATAGCAACACCCCATCTCTACAAAAATAAAGAAATTAGATGTGGTGGCC
TGCATCTGTAGTCCAGCTACTTGGGAGACTGAGACCAGTAGATAACTTGAGCCCAGGAGTTCAAGGCTATGATTGTGTCACTGCACTCCA
GCCTGGGCCACAGAGGAAGACTCAGACTCAAAAGAAGAAGAAGAACACAGAAGAAAAGCAGAAACAAGAAGAAGATACAGATGTAACTTT

>In-frame_ENST00000457346_ENST00000541669_TCGA-FD-A5BV-01A_SCUBE2_chr11_9090917_-_LDHC_chr11_18451284_length(amino acids)=473AA_start in transcript=51_stop in transcript=1472
MPATAEPSMGVAGRNRPGAAWAVLLLLLLLPPLLLLAGAVPPGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGR
QCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSE
EGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCIYYSVSANSRIVIVTAGARQQEGETRLALVQRNVAIMKSIIPAIVHYSP
DCKILVVSNPVDILTYIVWKISGLPVTRVIGSGCNLDSARFRYLIGEKLGVHPTSCHGWIIGEHGDSSVPLWSGVNVAGVALKTLDPKLG
TDSDKEHWKNIHKQVIQSAYEIIKLKGYTSWAIGLSVMDLVGSILKNLRRVHPVSTMVKGLYGIKEELFLSIPCVLGRNGVSDVVKINLN

--------------------------------------------------------------
>In-frame_ENST00000457346_ENST00000280704_TCGA-FD-A5BV-01A_SCUBE2_chr11_9090917_-_LDHC_chr11_18451284_length(transcript)=1589nt_BP=718nt
CCGCGCACACCTCCCCGCGCCGCCGCCGCCACCGCCCGCACTCCGCCGCCTCTGCCCGCAACCGCTGAGCCATCCATGGGGGTCGCGGGC
CGCAACCGTCCCGGGGCGGCCTGGGCGGTGCTGCTGCTGCTGCTGCTGCTGCCGCCACTGCTGCTGCTGGCGGGGGCCGTCCCGCCGGGT
CGGGGCCGTGCCGCGGGGCCGCAGGAGGATGTAGATGAGTGTGCCCAAGGGCTAGATGACTGCCATGCCGACGCCCTGTGTCAGAACACA
CCCACCTCCTACAAGTGCTCCTGCAAGCCTGGCTACCAAGGGGAAGGCAGGCAGTGTGAGGACATCGATGAATGTGGAAATGAGCTCAAT
GGAGGCTGTGTCCATGACTGTTTGAATATTCCAGGCAATTATCGTTGCACTTGTTTTGATGGCTTCATGTTGGCTCATGACGGTCATAAT
TGTCTTGATGTGGACGAGTGCCTGGAGAACAATGGCGGCTGCCAGCATACCTGTGTCAACGTCATGGGGAGCTATGAGTGCTGCTGCAAG
GAGGGGTTTTTCCTGAGTGACAATCAGCACACCTGCATTCACCGCTCGGAAGAGGGCCTGAGCTGCATGAATAAGGATCACGGCTGTAGT
CACATCTGCAAGGAGGCCCCAAGGGGCAGCGTCGCCTGTGAGTGCAGGCCTGGTTTTGAGCTGGCCAAGAACCAGAGAGACTGCATCTAT
TACAGTGTATCTGCAAACTCCAGAATAGTTATTGTCACAGCAGGTGCAAGGCAGCAGGAGGGAGAAACTCGCCTTGCCCTGGTCCAACGT
AATGTGGCTATAATGAAATCAATCATTCCTGCCATAGTCCATTATAGTCCTGATTGTAAAATTCTTGTTGTTTCAAATCCAGTGGATATT
TTGACATATATAGTCTGGAAGATAAGTGGCTTACCTGTAACTCGTGTAATTGGAAGTGGTTGTAATCTAGACTCTGCCCGTTTCCGTTAC
CTAATTGGAGAAAAGTTGGGTGTCCACCCCACAAGCTGCCATGGTTGGATTATTGGAGAACATGGTGATTCTAGTGTGCCCTTATGGAGT
GGGGTGAATGTTGCTGGTGTTGCTCTGAAGACTCTGGACCCTAAATTAGGAACGGATTCAGATAAGGAACACTGGAAAAATATCCATAAA
CAAGTTATTCAAAGTGCCTATGAAATTATCAAGCTGAAGGGGTATACCTCTTGGGCTATTGGACTGTCTGTGATGGATTTGGTAGGATCC
ATTTTGAAAAATCTTAGGAGAGTGCACCCAGTTTCCACCATGGTTAAGGGATTATATGGAATAAAAGAAGAACTCTTTCTCAGTATCCCT
TGTGTCTTGGGGCGGAATGGTGTCTCAGATGTTGTGAAAATTAACTTGAATTCTGAGGAGGAGGCCCTTTTCAAGAAGAGTGCAGAAACA
CTTTGGAATATTCAAAAGGATCTAATATTTTAAATTAAAGCCTTCTAATGTTCCACTGTTTGGAGAACAGAAGATAGCAGGCTGTGTATT

>In-frame_ENST00000457346_ENST00000280704_TCGA-FD-A5BV-01A_SCUBE2_chr11_9090917_-_LDHC_chr11_18451284_length(amino acids)=473AA_start in transcript=51_stop in transcript=1472
MPATAEPSMGVAGRNRPGAAWAVLLLLLLLPPLLLLAGAVPPGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGR
QCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSE
EGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCIYYSVSANSRIVIVTAGARQQEGETRLALVQRNVAIMKSIIPAIVHYSP
DCKILVVSNPVDILTYIVWKISGLPVTRVIGSGCNLDSARFRYLIGEKLGVHPTSCHGWIIGEHGDSSVPLWSGVNVAGVALKTLDPKLG
TDSDKEHWKNIHKQVIQSAYEIIKLKGYTSWAIGLSVMDLVGSILKNLRRVHPVSTMVKGLYGIKEELFLSIPCVLGRNGVSDVVKINLN

--------------------------------------------------------------
>In-frame_ENST00000457346_ENST00000544105_TCGA-FD-A5BV-01A_SCUBE2_chr11_9090917_-_LDHC_chr11_18451284_length(transcript)=1349nt_BP=718nt
CCGCGCACACCTCCCCGCGCCGCCGCCGCCACCGCCCGCACTCCGCCGCCTCTGCCCGCAACCGCTGAGCCATCCATGGGGGTCGCGGGC
CGCAACCGTCCCGGGGCGGCCTGGGCGGTGCTGCTGCTGCTGCTGCTGCTGCCGCCACTGCTGCTGCTGGCGGGGGCCGTCCCGCCGGGT
CGGGGCCGTGCCGCGGGGCCGCAGGAGGATGTAGATGAGTGTGCCCAAGGGCTAGATGACTGCCATGCCGACGCCCTGTGTCAGAACACA
CCCACCTCCTACAAGTGCTCCTGCAAGCCTGGCTACCAAGGGGAAGGCAGGCAGTGTGAGGACATCGATGAATGTGGAAATGAGCTCAAT
GGAGGCTGTGTCCATGACTGTTTGAATATTCCAGGCAATTATCGTTGCACTTGTTTTGATGGCTTCATGTTGGCTCATGACGGTCATAAT
TGTCTTGATGTGGACGAGTGCCTGGAGAACAATGGCGGCTGCCAGCATACCTGTGTCAACGTCATGGGGAGCTATGAGTGCTGCTGCAAG
GAGGGGTTTTTCCTGAGTGACAATCAGCACACCTGCATTCACCGCTCGGAAGAGGGCCTGAGCTGCATGAATAAGGATCACGGCTGTAGT
CACATCTGCAAGGAGGCCCCAAGGGGCAGCGTCGCCTGTGAGTGCAGGCCTGGTTTTGAGCTGGCCAAGAACCAGAGAGACTGCATCTAT
TACAGTGTATCTGCAAACTCCAGAATAGTTATTGTCACAGCAGGTGCAAGGCAGCAGGAGGGAGAAACTCGCCTTGCCCTGGTCCAACGT
AATGTGGCTATAATGAAATCAATCATTCCTGCCATAGTCCATTATAGTCCTGATTGTAAAATTCTTGTTGTTTCAAATCCAGTGGATATT
TTGACATATATAGTCTGGAAGATAAGTGGCTTACCTGTAACTCGTGTAATTGGAAGTGGTTGTAATCTAGACTCTGCCCGTTTCCGTTAC
CTAATTGGAGAAAAGTTGGGTGTCCACCCCACAAGCTGCCATGGTTGGATTATTGGAGAACATGGTGATTCTAGTGTGCCCTTATGGAGT
GGGGTGAATGTTGCTGGTGTTGCTCTGAAGACTCTGGACCCTAAATTAGGAACGGATTCAGATAAGGAACACTGGAAAAATATCCATAAA
CAAGTTATTCAAAGGGATTATATGGAATAAAAGAAGAACTCTTTCTCAGTATCCCTTGTGTCTTGGGGCGGAATGGTGTCTCAGATGTTG

>In-frame_ENST00000457346_ENST00000544105_TCGA-FD-A5BV-01A_SCUBE2_chr11_9090917_-_LDHC_chr11_18451284_length(amino acids)=382AA_start in transcript=51_stop in transcript=1199
MPATAEPSMGVAGRNRPGAAWAVLLLLLLLPPLLLLAGAVPPGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGR
QCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSE
EGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCIYYSVSANSRIVIVTAGARQQEGETRLALVQRNVAIMKSIIPAIVHYSP
DCKILVVSNPVDILTYIVWKISGLPVTRVIGSGCNLDSARFRYLIGEKLGVHPTSCHGWIIGEHGDSSVPLWSGVNVAGVALKTLDPKLG

--------------------------------------------------------------
>In-frame_ENST00000309263_ENST00000541669_TCGA-FD-A5BV-01A_SCUBE2_chr11_9090917_-_LDHC_chr11_18451284_length(transcript)=2402nt_BP=716nt
GCGCACACCTCCCCGCGCCGCCGCCGCCACCGCCCGCACTCCGCCGCCTCTGCCCGCAACCGCTGAGCCATCCATGGGGGTCGCGGGCCG
CAACCGTCCCGGGGCGGCCTGGGCGGTGCTGCTGCTGCTGCTGCTGCTGCCGCCACTGCTGCTGCTGGCGGGGGCCGTCCCGCCGGGTCG
GGGCCGTGCCGCGGGGCCGCAGGAGGATGTAGATGAGTGTGCCCAAGGGCTAGATGACTGCCATGCCGACGCCCTGTGTCAGAACACACC
CACCTCCTACAAGTGCTCCTGCAAGCCTGGCTACCAAGGGGAAGGCAGGCAGTGTGAGGACATCGATGAATGTGGAAATGAGCTCAATGG
AGGCTGTGTCCATGACTGTTTGAATATTCCAGGCAATTATCGTTGCACTTGTTTTGATGGCTTCATGTTGGCTCATGACGGTCATAATTG
TCTTGATGTGGACGAGTGCCTGGAGAACAATGGCGGCTGCCAGCATACCTGTGTCAACGTCATGGGGAGCTATGAGTGCTGCTGCAAGGA
GGGGTTTTTCCTGAGTGACAATCAGCACACCTGCATTCACCGCTCGGAAGAGGGCCTGAGCTGCATGAATAAGGATCACGGCTGTAGTCA
CATCTGCAAGGAGGCCCCAAGGGGCAGCGTCGCCTGTGAGTGCAGGCCTGGTTTTGAGCTGGCCAAGAACCAGAGAGACTGCATCTATTA
CAGTGTATCTGCAAACTCCAGAATAGTTATTGTCACAGCAGGTGCAAGGCAGCAGGAGGGAGAAACTCGCCTTGCCCTGGTCCAACGTAA
TGTGGCTATAATGAAATCAATCATTCCTGCCATAGTCCATTATAGTCCTGATTGTAAAATTCTTGTTGTTTCAAATCCAGTGGATATTTT
GACATATATAGTCTGGAAGATAAGTGGCTTACCTGTAACTCGTGTAATTGGAAGTGGTTGTAATCTAGACTCTGCCCGTTTCCGTTACCT
AATTGGAGAAAAGTTGGGTGTCCACCCCACAAGCTGCCATGGTTGGATTATTGGAGAACATGGTGATTCTAGTGTGCCCTTATGGAGTGG
GGTGAATGTTGCTGGTGTTGCTCTGAAGACTCTGGACCCTAAATTAGGAACGGATTCAGATAAGGAACACTGGAAAAATATCCATAAACA
AGTTATTCAAAGTGCCTATGAAATTATCAAGCTGAAGGGGTATACCTCTTGGGCTATTGGACTGTCTGTGATGGATTTGGTAGGATCCAT
TTTGAAAAATCTTAGGAGAGTGCACCCAGTTTCCACCATGGTTAAGGGATTATATGGAATAAAAGAAGAACTCTTTCTCAGTATCCCTTG
TGTCTTGGGGCGGAATGGTGTCTCAGATGTTGTGAAAATTAACTTGAATTCTGAGGAGGAGGCCCTTTTCAAGAAGAGTGCAGAAACACT
TTGGAATATTCAAAAGGATCTAATATTTTAAATTAAAGCCTTCTAATGTTCCACTGTTTGGAGAACAGAAGATAGCAGGCTGTGTATTTT
AAATTTTGAAAGTATTTTCATTTGATCTTTAAAAAATAAAAACAAATTGGAGACCTGTGACATAACTCTAGTCTCTCAAGATTAGAACGA
GCAAATGGTAAAGAGATTTTCCTCTTTAAGAATCATTTATAGCTCTATTCTAATGATACCCAATCTGTACAGGTGTAAGTTATACTTCTG
AGGTATGTCACATATGTTAGAGTGCCTTCAGATGTAGTAGAATATGTATAATCACTATAATACAGAGCTTTGATTCTTTTCACAAACCAA
GCCCTTTTTCTAGTATTACAATTTTATCTTGTACTTTCATCCGTTAGAGTACCAGCATATTCACTTCATTACATTAGCGTCATATGTTTA
TGTATAATCATTATAAATGTGGCCGGGCACTGCAGCCTGGGTGAAAGAGTGAGGCTCTGTCTCAAAAAAAATCATTATAAATGCTTATTT
TTAAGACCATATATATCAAAAAGAAATAAAAAGCTGAGTGCTGTGGCTCATGGCTGTAATCCCAGTGCTTTGGGAGGGTGAGGCAAGAGG
ATCACATGAGTCCAGGAGTTTGAGACCAGCCTTGGCAACATAGCAACACCCCATCTCTACAAAAATAAAGAAATTAGATGTGGTGGCCTG
CATCTGTAGTCCAGCTACTTGGGAGACTGAGACCAGTAGATAACTTGAGCCCAGGAGTTCAAGGCTATGATTGTGTCACTGCACTCCAGC
CTGGGCCACAGAGGAAGACTCAGACTCAAAAGAAGAAGAAGAACACAGAAGAAAAGCAGAAACAAGAAGAAGATACAGATGTAACTTTAC

>In-frame_ENST00000309263_ENST00000541669_TCGA-FD-A5BV-01A_SCUBE2_chr11_9090917_-_LDHC_chr11_18451284_length(amino acids)=473AA_start in transcript=49_stop in transcript=1470
MPATAEPSMGVAGRNRPGAAWAVLLLLLLLPPLLLLAGAVPPGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGR
QCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSE
EGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCIYYSVSANSRIVIVTAGARQQEGETRLALVQRNVAIMKSIIPAIVHYSP
DCKILVVSNPVDILTYIVWKISGLPVTRVIGSGCNLDSARFRYLIGEKLGVHPTSCHGWIIGEHGDSSVPLWSGVNVAGVALKTLDPKLG
TDSDKEHWKNIHKQVIQSAYEIIKLKGYTSWAIGLSVMDLVGSILKNLRRVHPVSTMVKGLYGIKEELFLSIPCVLGRNGVSDVVKINLN

--------------------------------------------------------------
>In-frame_ENST00000309263_ENST00000280704_TCGA-FD-A5BV-01A_SCUBE2_chr11_9090917_-_LDHC_chr11_18451284_length(transcript)=1587nt_BP=716nt
GCGCACACCTCCCCGCGCCGCCGCCGCCACCGCCCGCACTCCGCCGCCTCTGCCCGCAACCGCTGAGCCATCCATGGGGGTCGCGGGCCG
CAACCGTCCCGGGGCGGCCTGGGCGGTGCTGCTGCTGCTGCTGCTGCTGCCGCCACTGCTGCTGCTGGCGGGGGCCGTCCCGCCGGGTCG
GGGCCGTGCCGCGGGGCCGCAGGAGGATGTAGATGAGTGTGCCCAAGGGCTAGATGACTGCCATGCCGACGCCCTGTGTCAGAACACACC
CACCTCCTACAAGTGCTCCTGCAAGCCTGGCTACCAAGGGGAAGGCAGGCAGTGTGAGGACATCGATGAATGTGGAAATGAGCTCAATGG
AGGCTGTGTCCATGACTGTTTGAATATTCCAGGCAATTATCGTTGCACTTGTTTTGATGGCTTCATGTTGGCTCATGACGGTCATAATTG
TCTTGATGTGGACGAGTGCCTGGAGAACAATGGCGGCTGCCAGCATACCTGTGTCAACGTCATGGGGAGCTATGAGTGCTGCTGCAAGGA
GGGGTTTTTCCTGAGTGACAATCAGCACACCTGCATTCACCGCTCGGAAGAGGGCCTGAGCTGCATGAATAAGGATCACGGCTGTAGTCA
CATCTGCAAGGAGGCCCCAAGGGGCAGCGTCGCCTGTGAGTGCAGGCCTGGTTTTGAGCTGGCCAAGAACCAGAGAGACTGCATCTATTA
CAGTGTATCTGCAAACTCCAGAATAGTTATTGTCACAGCAGGTGCAAGGCAGCAGGAGGGAGAAACTCGCCTTGCCCTGGTCCAACGTAA
TGTGGCTATAATGAAATCAATCATTCCTGCCATAGTCCATTATAGTCCTGATTGTAAAATTCTTGTTGTTTCAAATCCAGTGGATATTTT
GACATATATAGTCTGGAAGATAAGTGGCTTACCTGTAACTCGTGTAATTGGAAGTGGTTGTAATCTAGACTCTGCCCGTTTCCGTTACCT
AATTGGAGAAAAGTTGGGTGTCCACCCCACAAGCTGCCATGGTTGGATTATTGGAGAACATGGTGATTCTAGTGTGCCCTTATGGAGTGG
GGTGAATGTTGCTGGTGTTGCTCTGAAGACTCTGGACCCTAAATTAGGAACGGATTCAGATAAGGAACACTGGAAAAATATCCATAAACA
AGTTATTCAAAGTGCCTATGAAATTATCAAGCTGAAGGGGTATACCTCTTGGGCTATTGGACTGTCTGTGATGGATTTGGTAGGATCCAT
TTTGAAAAATCTTAGGAGAGTGCACCCAGTTTCCACCATGGTTAAGGGATTATATGGAATAAAAGAAGAACTCTTTCTCAGTATCCCTTG
TGTCTTGGGGCGGAATGGTGTCTCAGATGTTGTGAAAATTAACTTGAATTCTGAGGAGGAGGCCCTTTTCAAGAAGAGTGCAGAAACACT
TTGGAATATTCAAAAGGATCTAATATTTTAAATTAAAGCCTTCTAATGTTCCACTGTTTGGAGAACAGAAGATAGCAGGCTGTGTATTTT

>In-frame_ENST00000309263_ENST00000280704_TCGA-FD-A5BV-01A_SCUBE2_chr11_9090917_-_LDHC_chr11_18451284_length(amino acids)=473AA_start in transcript=49_stop in transcript=1470
MPATAEPSMGVAGRNRPGAAWAVLLLLLLLPPLLLLAGAVPPGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGR
QCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSE
EGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCIYYSVSANSRIVIVTAGARQQEGETRLALVQRNVAIMKSIIPAIVHYSP
DCKILVVSNPVDILTYIVWKISGLPVTRVIGSGCNLDSARFRYLIGEKLGVHPTSCHGWIIGEHGDSSVPLWSGVNVAGVALKTLDPKLG
TDSDKEHWKNIHKQVIQSAYEIIKLKGYTSWAIGLSVMDLVGSILKNLRRVHPVSTMVKGLYGIKEELFLSIPCVLGRNGVSDVVKINLN

--------------------------------------------------------------
>In-frame_ENST00000309263_ENST00000544105_TCGA-FD-A5BV-01A_SCUBE2_chr11_9090917_-_LDHC_chr11_18451284_length(transcript)=1347nt_BP=716nt
GCGCACACCTCCCCGCGCCGCCGCCGCCACCGCCCGCACTCCGCCGCCTCTGCCCGCAACCGCTGAGCCATCCATGGGGGTCGCGGGCCG
CAACCGTCCCGGGGCGGCCTGGGCGGTGCTGCTGCTGCTGCTGCTGCTGCCGCCACTGCTGCTGCTGGCGGGGGCCGTCCCGCCGGGTCG
GGGCCGTGCCGCGGGGCCGCAGGAGGATGTAGATGAGTGTGCCCAAGGGCTAGATGACTGCCATGCCGACGCCCTGTGTCAGAACACACC
CACCTCCTACAAGTGCTCCTGCAAGCCTGGCTACCAAGGGGAAGGCAGGCAGTGTGAGGACATCGATGAATGTGGAAATGAGCTCAATGG
AGGCTGTGTCCATGACTGTTTGAATATTCCAGGCAATTATCGTTGCACTTGTTTTGATGGCTTCATGTTGGCTCATGACGGTCATAATTG
TCTTGATGTGGACGAGTGCCTGGAGAACAATGGCGGCTGCCAGCATACCTGTGTCAACGTCATGGGGAGCTATGAGTGCTGCTGCAAGGA
GGGGTTTTTCCTGAGTGACAATCAGCACACCTGCATTCACCGCTCGGAAGAGGGCCTGAGCTGCATGAATAAGGATCACGGCTGTAGTCA
CATCTGCAAGGAGGCCCCAAGGGGCAGCGTCGCCTGTGAGTGCAGGCCTGGTTTTGAGCTGGCCAAGAACCAGAGAGACTGCATCTATTA
CAGTGTATCTGCAAACTCCAGAATAGTTATTGTCACAGCAGGTGCAAGGCAGCAGGAGGGAGAAACTCGCCTTGCCCTGGTCCAACGTAA
TGTGGCTATAATGAAATCAATCATTCCTGCCATAGTCCATTATAGTCCTGATTGTAAAATTCTTGTTGTTTCAAATCCAGTGGATATTTT
GACATATATAGTCTGGAAGATAAGTGGCTTACCTGTAACTCGTGTAATTGGAAGTGGTTGTAATCTAGACTCTGCCCGTTTCCGTTACCT
AATTGGAGAAAAGTTGGGTGTCCACCCCACAAGCTGCCATGGTTGGATTATTGGAGAACATGGTGATTCTAGTGTGCCCTTATGGAGTGG
GGTGAATGTTGCTGGTGTTGCTCTGAAGACTCTGGACCCTAAATTAGGAACGGATTCAGATAAGGAACACTGGAAAAATATCCATAAACA
AGTTATTCAAAGGGATTATATGGAATAAAAGAAGAACTCTTTCTCAGTATCCCTTGTGTCTTGGGGCGGAATGGTGTCTCAGATGTTGTG

>In-frame_ENST00000309263_ENST00000544105_TCGA-FD-A5BV-01A_SCUBE2_chr11_9090917_-_LDHC_chr11_18451284_length(amino acids)=382AA_start in transcript=49_stop in transcript=1197
MPATAEPSMGVAGRNRPGAAWAVLLLLLLLPPLLLLAGAVPPGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGR
QCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSE
EGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCIYYSVSANSRIVIVTAGARQQEGETRLALVQRNVAIMKSIIPAIVHYSP
DCKILVVSNPVDILTYIVWKISGLPVTRVIGSGCNLDSARFRYLIGEKLGVHPTSCHGWIIGEHGDSSVPLWSGVNVAGVALKTLDPKLG

--------------------------------------------------------------
>In-frame_ENST00000450649_ENST00000541669_TCGA-FD-A5BV-01A_SCUBE2_chr11_9090917_-_LDHC_chr11_18451284_length(transcript)=2347nt_BP=661nt
GCAACCGCTGAGCCATCCATGGGGGTCGCGGGCCGCAACCGTCCCGGGGCGGCCTGGGCGGTGCTGCTGCTGCTGCTGCTGCTGCCGCCA
CTGCTGCTGCTGGCGGGGGCCGTCCCGCCGGGTCGGGGCCGTGCCGCGGGGCCGCAGGAGGATGTAGATGAGTGTGCCCAAGGGCTAGAT
GACTGCCATGCCGACGCCCTGTGTCAGAACACACCCACCTCCTACAAGTGCTCCTGCAAGCCTGGCTACCAAGGGGAAGGCAGGCAGTGT
GAGGACATCGATGAATGTGGAAATGAGCTCAATGGAGGCTGTGTCCATGACTGTTTGAATATTCCAGGCAATTATCGTTGCACTTGTTTT
GATGGCTTCATGTTGGCTCATGACGGTCATAATTGTCTTGATGTGGACGAGTGCCTGGAGAACAATGGCGGCTGCCAGCATACCTGTGTC
AACGTCATGGGGAGCTATGAGTGCTGCTGCAAGGAGGGGTTTTTCCTGAGTGACAATCAGCACACCTGCATTCACCGCTCGGAAGAGGGC
CTGAGCTGCATGAATAAGGATCACGGCTGTAGTCACATCTGCAAGGAGGCCCCAAGGGGCAGCGTCGCCTGTGAGTGCAGGCCTGGTTTT
GAGCTGGCCAAGAACCAGAGAGACTGCATCTATTACAGTGTATCTGCAAACTCCAGAATAGTTATTGTCACAGCAGGTGCAAGGCAGCAG
GAGGGAGAAACTCGCCTTGCCCTGGTCCAACGTAATGTGGCTATAATGAAATCAATCATTCCTGCCATAGTCCATTATAGTCCTGATTGT
AAAATTCTTGTTGTTTCAAATCCAGTGGATATTTTGACATATATAGTCTGGAAGATAAGTGGCTTACCTGTAACTCGTGTAATTGGAAGT
GGTTGTAATCTAGACTCTGCCCGTTTCCGTTACCTAATTGGAGAAAAGTTGGGTGTCCACCCCACAAGCTGCCATGGTTGGATTATTGGA
GAACATGGTGATTCTAGTGTGCCCTTATGGAGTGGGGTGAATGTTGCTGGTGTTGCTCTGAAGACTCTGGACCCTAAATTAGGAACGGAT
TCAGATAAGGAACACTGGAAAAATATCCATAAACAAGTTATTCAAAGTGCCTATGAAATTATCAAGCTGAAGGGGTATACCTCTTGGGCT
ATTGGACTGTCTGTGATGGATTTGGTAGGATCCATTTTGAAAAATCTTAGGAGAGTGCACCCAGTTTCCACCATGGTTAAGGGATTATAT
GGAATAAAAGAAGAACTCTTTCTCAGTATCCCTTGTGTCTTGGGGCGGAATGGTGTCTCAGATGTTGTGAAAATTAACTTGAATTCTGAG
GAGGAGGCCCTTTTCAAGAAGAGTGCAGAAACACTTTGGAATATTCAAAAGGATCTAATATTTTAAATTAAAGCCTTCTAATGTTCCACT
GTTTGGAGAACAGAAGATAGCAGGCTGTGTATTTTAAATTTTGAAAGTATTTTCATTTGATCTTTAAAAAATAAAAACAAATTGGAGACC
TGTGACATAACTCTAGTCTCTCAAGATTAGAACGAGCAAATGGTAAAGAGATTTTCCTCTTTAAGAATCATTTATAGCTCTATTCTAATG
ATACCCAATCTGTACAGGTGTAAGTTATACTTCTGAGGTATGTCACATATGTTAGAGTGCCTTCAGATGTAGTAGAATATGTATAATCAC
TATAATACAGAGCTTTGATTCTTTTCACAAACCAAGCCCTTTTTCTAGTATTACAATTTTATCTTGTACTTTCATCCGTTAGAGTACCAG
CATATTCACTTCATTACATTAGCGTCATATGTTTATGTATAATCATTATAAATGTGGCCGGGCACTGCAGCCTGGGTGAAAGAGTGAGGC
TCTGTCTCAAAAAAAATCATTATAAATGCTTATTTTTAAGACCATATATATCAAAAAGAAATAAAAAGCTGAGTGCTGTGGCTCATGGCT
GTAATCCCAGTGCTTTGGGAGGGTGAGGCAAGAGGATCACATGAGTCCAGGAGTTTGAGACCAGCCTTGGCAACATAGCAACACCCCATC
TCTACAAAAATAAAGAAATTAGATGTGGTGGCCTGCATCTGTAGTCCAGCTACTTGGGAGACTGAGACCAGTAGATAACTTGAGCCCAGG
AGTTCAAGGCTATGATTGTGTCACTGCACTCCAGCCTGGGCCACAGAGGAAGACTCAGACTCAAAAGAAGAAGAAGAACACAGAAGAAAA
GCAGAAACAAGAAGAAGATACAGATGTAACTTTACGATGTAAAAAATCTAAATAAGATTGTATTCAACTCTGCAAGTATTATACTAGTCA

>In-frame_ENST00000450649_ENST00000541669_TCGA-FD-A5BV-01A_SCUBE2_chr11_9090917_-_LDHC_chr11_18451284_length(amino acids)=465AA_start in transcript=18_stop in transcript=1415
MGVAGRNRPGAAWAVLLLLLLLPPLLLLAGAVPPGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDEC
GNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNK
DHGCSHICKEAPRGSVACECRPGFELAKNQRDCIYYSVSANSRIVIVTAGARQQEGETRLALVQRNVAIMKSIIPAIVHYSPDCKILVVS
NPVDILTYIVWKISGLPVTRVIGSGCNLDSARFRYLIGEKLGVHPTSCHGWIIGEHGDSSVPLWSGVNVAGVALKTLDPKLGTDSDKEHW
KNIHKQVIQSAYEIIKLKGYTSWAIGLSVMDLVGSILKNLRRVHPVSTMVKGLYGIKEELFLSIPCVLGRNGVSDVVKINLNSEEEALFK

--------------------------------------------------------------
>In-frame_ENST00000450649_ENST00000280704_TCGA-FD-A5BV-01A_SCUBE2_chr11_9090917_-_LDHC_chr11_18451284_length(transcript)=1532nt_BP=661nt
GCAACCGCTGAGCCATCCATGGGGGTCGCGGGCCGCAACCGTCCCGGGGCGGCCTGGGCGGTGCTGCTGCTGCTGCTGCTGCTGCCGCCA
CTGCTGCTGCTGGCGGGGGCCGTCCCGCCGGGTCGGGGCCGTGCCGCGGGGCCGCAGGAGGATGTAGATGAGTGTGCCCAAGGGCTAGAT
GACTGCCATGCCGACGCCCTGTGTCAGAACACACCCACCTCCTACAAGTGCTCCTGCAAGCCTGGCTACCAAGGGGAAGGCAGGCAGTGT
GAGGACATCGATGAATGTGGAAATGAGCTCAATGGAGGCTGTGTCCATGACTGTTTGAATATTCCAGGCAATTATCGTTGCACTTGTTTT
GATGGCTTCATGTTGGCTCATGACGGTCATAATTGTCTTGATGTGGACGAGTGCCTGGAGAACAATGGCGGCTGCCAGCATACCTGTGTC
AACGTCATGGGGAGCTATGAGTGCTGCTGCAAGGAGGGGTTTTTCCTGAGTGACAATCAGCACACCTGCATTCACCGCTCGGAAGAGGGC
CTGAGCTGCATGAATAAGGATCACGGCTGTAGTCACATCTGCAAGGAGGCCCCAAGGGGCAGCGTCGCCTGTGAGTGCAGGCCTGGTTTT
GAGCTGGCCAAGAACCAGAGAGACTGCATCTATTACAGTGTATCTGCAAACTCCAGAATAGTTATTGTCACAGCAGGTGCAAGGCAGCAG
GAGGGAGAAACTCGCCTTGCCCTGGTCCAACGTAATGTGGCTATAATGAAATCAATCATTCCTGCCATAGTCCATTATAGTCCTGATTGT
AAAATTCTTGTTGTTTCAAATCCAGTGGATATTTTGACATATATAGTCTGGAAGATAAGTGGCTTACCTGTAACTCGTGTAATTGGAAGT
GGTTGTAATCTAGACTCTGCCCGTTTCCGTTACCTAATTGGAGAAAAGTTGGGTGTCCACCCCACAAGCTGCCATGGTTGGATTATTGGA
GAACATGGTGATTCTAGTGTGCCCTTATGGAGTGGGGTGAATGTTGCTGGTGTTGCTCTGAAGACTCTGGACCCTAAATTAGGAACGGAT
TCAGATAAGGAACACTGGAAAAATATCCATAAACAAGTTATTCAAAGTGCCTATGAAATTATCAAGCTGAAGGGGTATACCTCTTGGGCT
ATTGGACTGTCTGTGATGGATTTGGTAGGATCCATTTTGAAAAATCTTAGGAGAGTGCACCCAGTTTCCACCATGGTTAAGGGATTATAT
GGAATAAAAGAAGAACTCTTTCTCAGTATCCCTTGTGTCTTGGGGCGGAATGGTGTCTCAGATGTTGTGAAAATTAACTTGAATTCTGAG
GAGGAGGCCCTTTTCAAGAAGAGTGCAGAAACACTTTGGAATATTCAAAAGGATCTAATATTTTAAATTAAAGCCTTCTAATGTTCCACT
GTTTGGAGAACAGAAGATAGCAGGCTGTGTATTTTAAATTTTGAAAGTATTTTCATTTGATCTTTAAAAAATAAAAACAAATTGGAGACC

>In-frame_ENST00000450649_ENST00000280704_TCGA-FD-A5BV-01A_SCUBE2_chr11_9090917_-_LDHC_chr11_18451284_length(amino acids)=465AA_start in transcript=18_stop in transcript=1415
MGVAGRNRPGAAWAVLLLLLLLPPLLLLAGAVPPGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDEC
GNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNK
DHGCSHICKEAPRGSVACECRPGFELAKNQRDCIYYSVSANSRIVIVTAGARQQEGETRLALVQRNVAIMKSIIPAIVHYSPDCKILVVS
NPVDILTYIVWKISGLPVTRVIGSGCNLDSARFRYLIGEKLGVHPTSCHGWIIGEHGDSSVPLWSGVNVAGVALKTLDPKLGTDSDKEHW
KNIHKQVIQSAYEIIKLKGYTSWAIGLSVMDLVGSILKNLRRVHPVSTMVKGLYGIKEELFLSIPCVLGRNGVSDVVKINLNSEEEALFK

--------------------------------------------------------------
>In-frame_ENST00000450649_ENST00000544105_TCGA-FD-A5BV-01A_SCUBE2_chr11_9090917_-_LDHC_chr11_18451284_length(transcript)=1292nt_BP=661nt
GCAACCGCTGAGCCATCCATGGGGGTCGCGGGCCGCAACCGTCCCGGGGCGGCCTGGGCGGTGCTGCTGCTGCTGCTGCTGCTGCCGCCA
CTGCTGCTGCTGGCGGGGGCCGTCCCGCCGGGTCGGGGCCGTGCCGCGGGGCCGCAGGAGGATGTAGATGAGTGTGCCCAAGGGCTAGAT
GACTGCCATGCCGACGCCCTGTGTCAGAACACACCCACCTCCTACAAGTGCTCCTGCAAGCCTGGCTACCAAGGGGAAGGCAGGCAGTGT
GAGGACATCGATGAATGTGGAAATGAGCTCAATGGAGGCTGTGTCCATGACTGTTTGAATATTCCAGGCAATTATCGTTGCACTTGTTTT
GATGGCTTCATGTTGGCTCATGACGGTCATAATTGTCTTGATGTGGACGAGTGCCTGGAGAACAATGGCGGCTGCCAGCATACCTGTGTC
AACGTCATGGGGAGCTATGAGTGCTGCTGCAAGGAGGGGTTTTTCCTGAGTGACAATCAGCACACCTGCATTCACCGCTCGGAAGAGGGC
CTGAGCTGCATGAATAAGGATCACGGCTGTAGTCACATCTGCAAGGAGGCCCCAAGGGGCAGCGTCGCCTGTGAGTGCAGGCCTGGTTTT
GAGCTGGCCAAGAACCAGAGAGACTGCATCTATTACAGTGTATCTGCAAACTCCAGAATAGTTATTGTCACAGCAGGTGCAAGGCAGCAG
GAGGGAGAAACTCGCCTTGCCCTGGTCCAACGTAATGTGGCTATAATGAAATCAATCATTCCTGCCATAGTCCATTATAGTCCTGATTGT
AAAATTCTTGTTGTTTCAAATCCAGTGGATATTTTGACATATATAGTCTGGAAGATAAGTGGCTTACCTGTAACTCGTGTAATTGGAAGT
GGTTGTAATCTAGACTCTGCCCGTTTCCGTTACCTAATTGGAGAAAAGTTGGGTGTCCACCCCACAAGCTGCCATGGTTGGATTATTGGA
GAACATGGTGATTCTAGTGTGCCCTTATGGAGTGGGGTGAATGTTGCTGGTGTTGCTCTGAAGACTCTGGACCCTAAATTAGGAACGGAT
TCAGATAAGGAACACTGGAAAAATATCCATAAACAAGTTATTCAAAGGGATTATATGGAATAAAAGAAGAACTCTTTCTCAGTATCCCTT
GTGTCTTGGGGCGGAATGGTGTCTCAGATGTTGTGAAAATTAACTTGAATTCTGAGGAGGAGGCCCTTTTCAAGAAGAGTGCAGAAACAC

>In-frame_ENST00000450649_ENST00000544105_TCGA-FD-A5BV-01A_SCUBE2_chr11_9090917_-_LDHC_chr11_18451284_length(amino acids)=374AA_start in transcript=18_stop in transcript=1142
MGVAGRNRPGAAWAVLLLLLLLPPLLLLAGAVPPGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDEC
GNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNK
DHGCSHICKEAPRGSVACECRPGFELAKNQRDCIYYSVSANSRIVIVTAGARQQEGETRLALVQRNVAIMKSIIPAIVHYSPDCKILVVS
NPVDILTYIVWKISGLPVTRVIGSGCNLDSARFRYLIGEKLGVHPTSCHGWIIGEHGDSSVPLWSGVNVAGVALKTLDPKLGTDSDKEHW

--------------------------------------------------------------
>In-frame_ENST00000520467_ENST00000541669_TCGA-FD-A5BV-01A_SCUBE2_chr11_9090917_-_LDHC_chr11_18451284_length(transcript)=2400nt_BP=714nt
GCACACCTCCCCGCGCCGCCGCCGCCACCGCCCGCACTCCGCCGCCTCTGCCCGCAACCGCTGAGCCATCCATGGGGGTCGCGGGCCGCA
ACCGTCCCGGGGCGGCCTGGGCGGTGCTGCTGCTGCTGCTGCTGCTGCCGCCACTGCTGCTGCTGGCGGGGGCCGTCCCGCCGGGTCGGG
GCCGTGCCGCGGGGCCGCAGGAGGATGTAGATGAGTGTGCCCAAGGGCTAGATGACTGCCATGCCGACGCCCTGTGTCAGAACACACCCA
CCTCCTACAAGTGCTCCTGCAAGCCTGGCTACCAAGGGGAAGGCAGGCAGTGTGAGGACATCGATGAATGTGGAAATGAGCTCAATGGAG
GCTGTGTCCATGACTGTTTGAATATTCCAGGCAATTATCGTTGCACTTGTTTTGATGGCTTCATGTTGGCTCATGACGGTCATAATTGTC
TTGATGTGGACGAGTGCCTGGAGAACAATGGCGGCTGCCAGCATACCTGTGTCAACGTCATGGGGAGCTATGAGTGCTGCTGCAAGGAGG
GGTTTTTCCTGAGTGACAATCAGCACACCTGCATTCACCGCTCGGAAGAGGGCCTGAGCTGCATGAATAAGGATCACGGCTGTAGTCACA
TCTGCAAGGAGGCCCCAAGGGGCAGCGTCGCCTGTGAGTGCAGGCCTGGTTTTGAGCTGGCCAAGAACCAGAGAGACTGCATCTATTACA
GTGTATCTGCAAACTCCAGAATAGTTATTGTCACAGCAGGTGCAAGGCAGCAGGAGGGAGAAACTCGCCTTGCCCTGGTCCAACGTAATG
TGGCTATAATGAAATCAATCATTCCTGCCATAGTCCATTATAGTCCTGATTGTAAAATTCTTGTTGTTTCAAATCCAGTGGATATTTTGA
CATATATAGTCTGGAAGATAAGTGGCTTACCTGTAACTCGTGTAATTGGAAGTGGTTGTAATCTAGACTCTGCCCGTTTCCGTTACCTAA
TTGGAGAAAAGTTGGGTGTCCACCCCACAAGCTGCCATGGTTGGATTATTGGAGAACATGGTGATTCTAGTGTGCCCTTATGGAGTGGGG
TGAATGTTGCTGGTGTTGCTCTGAAGACTCTGGACCCTAAATTAGGAACGGATTCAGATAAGGAACACTGGAAAAATATCCATAAACAAG
TTATTCAAAGTGCCTATGAAATTATCAAGCTGAAGGGGTATACCTCTTGGGCTATTGGACTGTCTGTGATGGATTTGGTAGGATCCATTT
TGAAAAATCTTAGGAGAGTGCACCCAGTTTCCACCATGGTTAAGGGATTATATGGAATAAAAGAAGAACTCTTTCTCAGTATCCCTTGTG
TCTTGGGGCGGAATGGTGTCTCAGATGTTGTGAAAATTAACTTGAATTCTGAGGAGGAGGCCCTTTTCAAGAAGAGTGCAGAAACACTTT
GGAATATTCAAAAGGATCTAATATTTTAAATTAAAGCCTTCTAATGTTCCACTGTTTGGAGAACAGAAGATAGCAGGCTGTGTATTTTAA
ATTTTGAAAGTATTTTCATTTGATCTTTAAAAAATAAAAACAAATTGGAGACCTGTGACATAACTCTAGTCTCTCAAGATTAGAACGAGC
AAATGGTAAAGAGATTTTCCTCTTTAAGAATCATTTATAGCTCTATTCTAATGATACCCAATCTGTACAGGTGTAAGTTATACTTCTGAG
GTATGTCACATATGTTAGAGTGCCTTCAGATGTAGTAGAATATGTATAATCACTATAATACAGAGCTTTGATTCTTTTCACAAACCAAGC
CCTTTTTCTAGTATTACAATTTTATCTTGTACTTTCATCCGTTAGAGTACCAGCATATTCACTTCATTACATTAGCGTCATATGTTTATG
TATAATCATTATAAATGTGGCCGGGCACTGCAGCCTGGGTGAAAGAGTGAGGCTCTGTCTCAAAAAAAATCATTATAAATGCTTATTTTT
AAGACCATATATATCAAAAAGAAATAAAAAGCTGAGTGCTGTGGCTCATGGCTGTAATCCCAGTGCTTTGGGAGGGTGAGGCAAGAGGAT
CACATGAGTCCAGGAGTTTGAGACCAGCCTTGGCAACATAGCAACACCCCATCTCTACAAAAATAAAGAAATTAGATGTGGTGGCCTGCA
TCTGTAGTCCAGCTACTTGGGAGACTGAGACCAGTAGATAACTTGAGCCCAGGAGTTCAAGGCTATGATTGTGTCACTGCACTCCAGCCT
GGGCCACAGAGGAAGACTCAGACTCAAAAGAAGAAGAAGAACACAGAAGAAAAGCAGAAACAAGAAGAAGATACAGATGTAACTTTACGA

>In-frame_ENST00000520467_ENST00000541669_TCGA-FD-A5BV-01A_SCUBE2_chr11_9090917_-_LDHC_chr11_18451284_length(amino acids)=473AA_start in transcript=47_stop in transcript=1468
MPATAEPSMGVAGRNRPGAAWAVLLLLLLLPPLLLLAGAVPPGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGR
QCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSE
EGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCIYYSVSANSRIVIVTAGARQQEGETRLALVQRNVAIMKSIIPAIVHYSP
DCKILVVSNPVDILTYIVWKISGLPVTRVIGSGCNLDSARFRYLIGEKLGVHPTSCHGWIIGEHGDSSVPLWSGVNVAGVALKTLDPKLG
TDSDKEHWKNIHKQVIQSAYEIIKLKGYTSWAIGLSVMDLVGSILKNLRRVHPVSTMVKGLYGIKEELFLSIPCVLGRNGVSDVVKINLN

--------------------------------------------------------------
>In-frame_ENST00000520467_ENST00000280704_TCGA-FD-A5BV-01A_SCUBE2_chr11_9090917_-_LDHC_chr11_18451284_length(transcript)=1585nt_BP=714nt
GCACACCTCCCCGCGCCGCCGCCGCCACCGCCCGCACTCCGCCGCCTCTGCCCGCAACCGCTGAGCCATCCATGGGGGTCGCGGGCCGCA
ACCGTCCCGGGGCGGCCTGGGCGGTGCTGCTGCTGCTGCTGCTGCTGCCGCCACTGCTGCTGCTGGCGGGGGCCGTCCCGCCGGGTCGGG
GCCGTGCCGCGGGGCCGCAGGAGGATGTAGATGAGTGTGCCCAAGGGCTAGATGACTGCCATGCCGACGCCCTGTGTCAGAACACACCCA
CCTCCTACAAGTGCTCCTGCAAGCCTGGCTACCAAGGGGAAGGCAGGCAGTGTGAGGACATCGATGAATGTGGAAATGAGCTCAATGGAG
GCTGTGTCCATGACTGTTTGAATATTCCAGGCAATTATCGTTGCACTTGTTTTGATGGCTTCATGTTGGCTCATGACGGTCATAATTGTC
TTGATGTGGACGAGTGCCTGGAGAACAATGGCGGCTGCCAGCATACCTGTGTCAACGTCATGGGGAGCTATGAGTGCTGCTGCAAGGAGG
GGTTTTTCCTGAGTGACAATCAGCACACCTGCATTCACCGCTCGGAAGAGGGCCTGAGCTGCATGAATAAGGATCACGGCTGTAGTCACA
TCTGCAAGGAGGCCCCAAGGGGCAGCGTCGCCTGTGAGTGCAGGCCTGGTTTTGAGCTGGCCAAGAACCAGAGAGACTGCATCTATTACA
GTGTATCTGCAAACTCCAGAATAGTTATTGTCACAGCAGGTGCAAGGCAGCAGGAGGGAGAAACTCGCCTTGCCCTGGTCCAACGTAATG
TGGCTATAATGAAATCAATCATTCCTGCCATAGTCCATTATAGTCCTGATTGTAAAATTCTTGTTGTTTCAAATCCAGTGGATATTTTGA
CATATATAGTCTGGAAGATAAGTGGCTTACCTGTAACTCGTGTAATTGGAAGTGGTTGTAATCTAGACTCTGCCCGTTTCCGTTACCTAA
TTGGAGAAAAGTTGGGTGTCCACCCCACAAGCTGCCATGGTTGGATTATTGGAGAACATGGTGATTCTAGTGTGCCCTTATGGAGTGGGG
TGAATGTTGCTGGTGTTGCTCTGAAGACTCTGGACCCTAAATTAGGAACGGATTCAGATAAGGAACACTGGAAAAATATCCATAAACAAG
TTATTCAAAGTGCCTATGAAATTATCAAGCTGAAGGGGTATACCTCTTGGGCTATTGGACTGTCTGTGATGGATTTGGTAGGATCCATTT
TGAAAAATCTTAGGAGAGTGCACCCAGTTTCCACCATGGTTAAGGGATTATATGGAATAAAAGAAGAACTCTTTCTCAGTATCCCTTGTG
TCTTGGGGCGGAATGGTGTCTCAGATGTTGTGAAAATTAACTTGAATTCTGAGGAGGAGGCCCTTTTCAAGAAGAGTGCAGAAACACTTT
GGAATATTCAAAAGGATCTAATATTTTAAATTAAAGCCTTCTAATGTTCCACTGTTTGGAGAACAGAAGATAGCAGGCTGTGTATTTTAA

>In-frame_ENST00000520467_ENST00000280704_TCGA-FD-A5BV-01A_SCUBE2_chr11_9090917_-_LDHC_chr11_18451284_length(amino acids)=473AA_start in transcript=47_stop in transcript=1468
MPATAEPSMGVAGRNRPGAAWAVLLLLLLLPPLLLLAGAVPPGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGR
QCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSE
EGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCIYYSVSANSRIVIVTAGARQQEGETRLALVQRNVAIMKSIIPAIVHYSP
DCKILVVSNPVDILTYIVWKISGLPVTRVIGSGCNLDSARFRYLIGEKLGVHPTSCHGWIIGEHGDSSVPLWSGVNVAGVALKTLDPKLG
TDSDKEHWKNIHKQVIQSAYEIIKLKGYTSWAIGLSVMDLVGSILKNLRRVHPVSTMVKGLYGIKEELFLSIPCVLGRNGVSDVVKINLN

--------------------------------------------------------------
>In-frame_ENST00000520467_ENST00000544105_TCGA-FD-A5BV-01A_SCUBE2_chr11_9090917_-_LDHC_chr11_18451284_length(transcript)=1345nt_BP=714nt
GCACACCTCCCCGCGCCGCCGCCGCCACCGCCCGCACTCCGCCGCCTCTGCCCGCAACCGCTGAGCCATCCATGGGGGTCGCGGGCCGCA
ACCGTCCCGGGGCGGCCTGGGCGGTGCTGCTGCTGCTGCTGCTGCTGCCGCCACTGCTGCTGCTGGCGGGGGCCGTCCCGCCGGGTCGGG
GCCGTGCCGCGGGGCCGCAGGAGGATGTAGATGAGTGTGCCCAAGGGCTAGATGACTGCCATGCCGACGCCCTGTGTCAGAACACACCCA
CCTCCTACAAGTGCTCCTGCAAGCCTGGCTACCAAGGGGAAGGCAGGCAGTGTGAGGACATCGATGAATGTGGAAATGAGCTCAATGGAG
GCTGTGTCCATGACTGTTTGAATATTCCAGGCAATTATCGTTGCACTTGTTTTGATGGCTTCATGTTGGCTCATGACGGTCATAATTGTC
TTGATGTGGACGAGTGCCTGGAGAACAATGGCGGCTGCCAGCATACCTGTGTCAACGTCATGGGGAGCTATGAGTGCTGCTGCAAGGAGG
GGTTTTTCCTGAGTGACAATCAGCACACCTGCATTCACCGCTCGGAAGAGGGCCTGAGCTGCATGAATAAGGATCACGGCTGTAGTCACA
TCTGCAAGGAGGCCCCAAGGGGCAGCGTCGCCTGTGAGTGCAGGCCTGGTTTTGAGCTGGCCAAGAACCAGAGAGACTGCATCTATTACA
GTGTATCTGCAAACTCCAGAATAGTTATTGTCACAGCAGGTGCAAGGCAGCAGGAGGGAGAAACTCGCCTTGCCCTGGTCCAACGTAATG
TGGCTATAATGAAATCAATCATTCCTGCCATAGTCCATTATAGTCCTGATTGTAAAATTCTTGTTGTTTCAAATCCAGTGGATATTTTGA
CATATATAGTCTGGAAGATAAGTGGCTTACCTGTAACTCGTGTAATTGGAAGTGGTTGTAATCTAGACTCTGCCCGTTTCCGTTACCTAA
TTGGAGAAAAGTTGGGTGTCCACCCCACAAGCTGCCATGGTTGGATTATTGGAGAACATGGTGATTCTAGTGTGCCCTTATGGAGTGGGG
TGAATGTTGCTGGTGTTGCTCTGAAGACTCTGGACCCTAAATTAGGAACGGATTCAGATAAGGAACACTGGAAAAATATCCATAAACAAG
TTATTCAAAGGGATTATATGGAATAAAAGAAGAACTCTTTCTCAGTATCCCTTGTGTCTTGGGGCGGAATGGTGTCTCAGATGTTGTGAA

>In-frame_ENST00000520467_ENST00000544105_TCGA-FD-A5BV-01A_SCUBE2_chr11_9090917_-_LDHC_chr11_18451284_length(amino acids)=382AA_start in transcript=47_stop in transcript=1195
MPATAEPSMGVAGRNRPGAAWAVLLLLLLLPPLLLLAGAVPPGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGR
QCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSE
EGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCIYYSVSANSRIVIVTAGARQQEGETRLALVQRNVAIMKSIIPAIVHYSP
DCKILVVSNPVDILTYIVWKISGLPVTRVIGSGCNLDSARFRYLIGEKLGVHPTSCHGWIIGEHGDSSVPLWSGVNVAGVALKTLDPKLG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SCUBE2-LDHC


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000309263-522847_856214.333333333333341000.0the cholesterol-anchor of SHH
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000450649-518847_856214.33333333333334808.0the cholesterol-anchor of SHH
HgeneSCUBE2chr11:9090917chr11:18451284ENST00000520467-522847_856214.33333333333334972.0the cholesterol-anchor of SHH


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SCUBE2-LDHC


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
TgeneLDHCP07864DB00157NADHSmall moleculeApproved|Nutraceutical
TgeneLDHCP07864DB00157NADHSmall moleculeApproved|Nutraceutical
TgeneLDHCP07864DB00157NADHSmall moleculeApproved|Nutraceutical

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Related Diseases for SCUBE2-LDHC


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneLDHCC0021364Male infertility2CTD_human
TgeneLDHCC0848676Subfertility, Male2CTD_human
TgeneLDHCC0917731Male sterility2CTD_human
TgeneLDHCC0024115Lung diseases1CTD_human