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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SCYL1-PACS1 (FusionGDB2 ID:79283)

Fusion Gene Summary for SCYL1-PACS1

check button Fusion gene summary
Fusion gene informationFusion gene name: SCYL1-PACS1
Fusion gene ID: 79283
HgeneTgene
Gene symbol

SCYL1

PACS1

Gene ID

57410

55690

Gene nameSCY1 like pseudokinase 1phosphofurin acidic cluster sorting protein 1
SynonymsGKLP|HT019|NKTL|NTKL|P105|SCAR21|TAPK|TEIF|TRAPMRD17|SHMS
Cytomap

11q13.1

11q13.1-q13.2

Type of geneprotein-codingprotein-coding
DescriptionN-terminal kinase-like proteinSCY1-like protein 1SCY1-like, kinase-like 1coated vesicle-associated kinase of 90 kDalikely ortholog of mouse N-terminal kinase-like proteintelomerase regulation-associated proteintelomerase transcriptional elements-intphosphofurin acidic cluster sorting protein 1PACS-1cytosolic sorting protein PACS-1
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000525364, ENST00000270176, 
ENST00000420247, ENST00000533862, 
ENST00000279270, ENST00000524944, 
ENST00000527009, ENST00000534462, 
ENST00000320580, ENST00000529757, 
ENST00000524815, 
Fusion gene scores* DoF score8 X 8 X 7=44821 X 18 X 12=4536
# samples 1426
** MAII scorelog2(14/448*10)=-1.67807190511264
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(26/4536*10)=-4.12483711191377
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SCYL1 [Title/Abstract] AND PACS1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSCYL1(65300276)-PACS1(65977833), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSCYL1

GO:0006890

retrograde vesicle-mediated transport, Golgi to ER

18556652


check buttonFusion gene breakpoints across SCYL1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across PACS1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4COADTCGA-A6-A56B-01ASCYL1chr11

65300276

+PACS1chr11

65977833

+


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Fusion Gene ORF analysis for SCYL1-PACS1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000525364ENST00000320580SCYL1chr11

65300276

+PACS1chr11

65977833

+
5CDS-intronENST00000525364ENST00000529757SCYL1chr11

65300276

+PACS1chr11

65977833

+
5CDS-intronENST00000525364ENST00000524815SCYL1chr11

65300276

+PACS1chr11

65977833

+
In-frameENST00000270176ENST00000320580SCYL1chr11

65300276

+PACS1chr11

65977833

+
5CDS-intronENST00000270176ENST00000529757SCYL1chr11

65300276

+PACS1chr11

65977833

+
5CDS-intronENST00000270176ENST00000524815SCYL1chr11

65300276

+PACS1chr11

65977833

+
In-frameENST00000420247ENST00000320580SCYL1chr11

65300276

+PACS1chr11

65977833

+
5CDS-intronENST00000420247ENST00000529757SCYL1chr11

65300276

+PACS1chr11

65977833

+
5CDS-intronENST00000420247ENST00000524815SCYL1chr11

65300276

+PACS1chr11

65977833

+
In-frameENST00000533862ENST00000320580SCYL1chr11

65300276

+PACS1chr11

65977833

+
5CDS-intronENST00000533862ENST00000529757SCYL1chr11

65300276

+PACS1chr11

65977833

+
5CDS-intronENST00000533862ENST00000524815SCYL1chr11

65300276

+PACS1chr11

65977833

+
In-frameENST00000279270ENST00000320580SCYL1chr11

65300276

+PACS1chr11

65977833

+
5CDS-intronENST00000279270ENST00000529757SCYL1chr11

65300276

+PACS1chr11

65977833

+
5CDS-intronENST00000279270ENST00000524815SCYL1chr11

65300276

+PACS1chr11

65977833

+
In-frameENST00000524944ENST00000320580SCYL1chr11

65300276

+PACS1chr11

65977833

+
5CDS-intronENST00000524944ENST00000529757SCYL1chr11

65300276

+PACS1chr11

65977833

+
5CDS-intronENST00000524944ENST00000524815SCYL1chr11

65300276

+PACS1chr11

65977833

+
In-frameENST00000527009ENST00000320580SCYL1chr11

65300276

+PACS1chr11

65977833

+
5CDS-intronENST00000527009ENST00000529757SCYL1chr11

65300276

+PACS1chr11

65977833

+
5CDS-intronENST00000527009ENST00000524815SCYL1chr11

65300276

+PACS1chr11

65977833

+
intron-3CDSENST00000534462ENST00000320580SCYL1chr11

65300276

+PACS1chr11

65977833

+
intron-intronENST00000534462ENST00000529757SCYL1chr11

65300276

+PACS1chr11

65977833

+
intron-intronENST00000534462ENST00000524815SCYL1chr11

65300276

+PACS1chr11

65977833

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000525364SCYL1chr1165300276+ENST00000320580PACS1chr1165977833+522213077737541225
ENST00000270176SCYL1chr1165300276+ENST00000320580PACS1chr1165977833+522213077737541225
ENST00000420247SCYL1chr1165300276+ENST00000320580PACS1chr1165977833+521412996937461225
ENST00000533862SCYL1chr1165300276+ENST00000320580PACS1chr1165977833+518712724237191225
ENST00000279270SCYL1chr1165300276+ENST00000320580PACS1chr1165977833+518612714137181225
ENST00000524944SCYL1chr1165300276+ENST00000320580PACS1chr1165977833+517812633337101225
ENST00000527009SCYL1chr1165300276+ENST00000320580PACS1chr1165977833+5195128027837271149

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000525364ENST00000320580SCYL1chr1165300276+PACS1chr1165977833+0.0008797740.9991202
ENST00000270176ENST00000320580SCYL1chr1165300276+PACS1chr1165977833+0.0008797740.9991202
ENST00000420247ENST00000320580SCYL1chr1165300276+PACS1chr1165977833+0.000866660.9991334
ENST00000533862ENST00000320580SCYL1chr1165300276+PACS1chr1165977833+0.000825630.9991743
ENST00000279270ENST00000320580SCYL1chr1165300276+PACS1chr1165977833+0.0008253520.99917465
ENST00000524944ENST00000320580SCYL1chr1165300276+PACS1chr1165977833+0.0008224640.9991775
ENST00000527009ENST00000320580SCYL1chr1165300276+PACS1chr1165977833+0.0012942580.99870574

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Fusion Genomic Features for SCYL1-PACS1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SCYL1chr1165300276+PACS1chr1165977832+2.42E-091
SCYL1chr1165300276+PACS1chr1165977832+2.42E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SCYL1-PACS1


check button Go to

FGviewer for the breakpoints of chr11:65300276-chr11:65977833

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSCYL1chr11:65300276chr11:65977833ENST00000270176+91814_314410.0809.0DomainProtein kinase
HgeneSCYL1chr11:65300276chr11:65977833ENST00000279270+91714_314410.0782.0DomainProtein kinase
HgeneSCYL1chr11:65300276chr11:65977833ENST00000420247+91814_314410.0792.0DomainProtein kinase
HgeneSCYL1chr11:65300276chr11:65977833ENST00000533862+91814_314410.0788.0DomainProtein kinase
HgeneSCYL1chr11:65300276chr11:65977833ENST00000270176+918350_388410.0809.0RepeatNote=HEAT 1
HgeneSCYL1chr11:65300276chr11:65977833ENST00000279270+917350_388410.0782.0RepeatNote=HEAT 1
HgeneSCYL1chr11:65300276chr11:65977833ENST00000420247+918350_388410.0792.0RepeatNote=HEAT 1
HgeneSCYL1chr11:65300276chr11:65977833ENST00000533862+918350_388410.0788.0RepeatNote=HEAT 1
TgenePACS1chr11:65300276chr11:65977833ENST00000320580124353_377148.0964.0Coiled coilOntology_term=ECO:0000255
TgenePACS1chr11:65300276chr11:65977833ENST00000320580124279_283148.0964.0Compositional biasNote=Poly-Glu
TgenePACS1chr11:65300276chr11:65977833ENST00000320580124168_175148.0964.0RegionNote=Involved in binding to AP-1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSCYL1chr11:65300276chr11:65977833ENST00000270176+918761_797410.0809.0Coiled coilOntology_term=ECO:0000255
HgeneSCYL1chr11:65300276chr11:65977833ENST00000279270+917761_797410.0782.0Coiled coilOntology_term=ECO:0000255
HgeneSCYL1chr11:65300276chr11:65977833ENST00000420247+918761_797410.0792.0Coiled coilOntology_term=ECO:0000255
HgeneSCYL1chr11:65300276chr11:65977833ENST00000533862+918761_797410.0788.0Coiled coilOntology_term=ECO:0000255
HgeneSCYL1chr11:65300276chr11:65977833ENST00000270176+918589_619410.0809.0Compositional biasNote=Pro-rich
HgeneSCYL1chr11:65300276chr11:65977833ENST00000279270+917589_619410.0782.0Compositional biasNote=Pro-rich
HgeneSCYL1chr11:65300276chr11:65977833ENST00000420247+918589_619410.0792.0Compositional biasNote=Pro-rich
HgeneSCYL1chr11:65300276chr11:65977833ENST00000533862+918589_619410.0788.0Compositional biasNote=Pro-rich
HgeneSCYL1chr11:65300276chr11:65977833ENST00000270176+918389_427410.0809.0RepeatNote=HEAT 2
HgeneSCYL1chr11:65300276chr11:65977833ENST00000270176+918507_545410.0809.0RepeatNote=HEAT 3
HgeneSCYL1chr11:65300276chr11:65977833ENST00000279270+917389_427410.0782.0RepeatNote=HEAT 2
HgeneSCYL1chr11:65300276chr11:65977833ENST00000279270+917507_545410.0782.0RepeatNote=HEAT 3
HgeneSCYL1chr11:65300276chr11:65977833ENST00000420247+918389_427410.0792.0RepeatNote=HEAT 2
HgeneSCYL1chr11:65300276chr11:65977833ENST00000420247+918507_545410.0792.0RepeatNote=HEAT 3
HgeneSCYL1chr11:65300276chr11:65977833ENST00000533862+918389_427410.0788.0RepeatNote=HEAT 2
HgeneSCYL1chr11:65300276chr11:65977833ENST00000533862+918507_545410.0788.0RepeatNote=HEAT 3
TgenePACS1chr11:65300276chr11:65977833ENST00000320580124112_115148.0964.0Compositional biasNote=Poly-Ser
TgenePACS1chr11:65300276chr11:65977833ENST0000032058012435_40148.0964.0Compositional biasNote=Poly-Gln
TgenePACS1chr11:65300276chr11:65977833ENST0000032058012455_84148.0964.0Compositional biasNote=Ser-rich
TgenePACS1chr11:65300276chr11:65977833ENST000003205801245_44148.0964.0Compositional biasNote=Gly-rich
TgenePACS1chr11:65300276chr11:65977833ENST0000032058012462_65148.0964.0Compositional biasNote=Poly-Ala


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Fusion Gene Sequence for SCYL1-PACS1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000525364_ENST00000320580_TCGA-A6-A56B-01A_SCYL1_chr11_65300276_+_PACS1_chr11_65977833_length(transcript)=5222nt_BP=1307nt
CTCTCCGCCCCGCCCCGGCTCGGGCGGCCGGAGGACCCGGAGCTAAGGCGCCCGAACCCGCGGCGGCGGTGGGGACGATGTGGTTCTTTG
CCCGGGACCCGGTCCGGGACTTTCCGTTCGAGCTCATCCCGGAGCCCCCAGAGGGCGGCCTGCCCGGGCCCTGGGCCCTGCACCGCGGCC
GCAAGAAGGCCACAGGCAGCCCCGTGTCCATCTTCGTCTATGATGTGAAGCCTGGCGCGGAAGAGCAGACCCAGGTGGCCAAAGCTGCCT
TCAAGCGCTTCAAAACTCTACGGCACCCCAACATCCTGGCTTACATCGATGGACTGGAGACAGAAAAATGCCTCCACGTCGTGACAGAGG
CTGTGACCCCGTTGGGAATATACCTCAAGGCGAGAGTGGAGGCTGGTGGCCTGAAGGAGCTGGAGATCTCCTGGGGGCTACACCAGATCG
TGAAAGCCCTCAGCTTCCTGGTCAACGACTGCAGCCTCATCCACAACAATGTCTGCATGGCCGCCGTGTTCGTGGACCGAGCTGGCGAGT
GGAAGCTTGGGGGCCTGGACTACATGTATTCGGCCCAGGGCAACGGTGGGGGACCTCCCCGCAAGGGGATCCCCGAGCTTGAGCAGTATG
ACCCCCCGGAGTTGGCTGACAGCAGTGGCAGAGTGGTCAGAGAGAAGTGGTCAGCAGACATGTGGCGCTTGGGCTGCCTCATTTGGGAAG
TCTTCAATGGGCCCCTACCTCGGGCAGCAGCCCTACGCAACCCTGGGAAGATCCCCAAAACGCTGGTGCCCCATTACTGTGAGCTGGTGG
GAGCAAACCCCAAGGTGCGTCCCAACCCAGCCCGCTTCCTGCAGAACTGCCGGGCACCTGGTGGCTTCATGAGCAACCGCTTTGTAGAAA
CCAACCTCTTCCTGGAGGAGATTCAGATCAAAGAGCCAGCCGAGAAGCAAAAATTCTTCCAGGAGCTGAGCAAGAGCCTGGACGCATTCC
CTGAGGATTTCTGTCGGCACAAGGTGCTGCCCCAGCTGCTGACCGCCTTCGAGTTCGGCAATGCTGGGGCCGTTGTCCTCACGCCCCTCT
TCAAGGTGGGCAAGTTCCTGAGCGCTGAGGAGTATCAGCAGAAGATCATCCCTGTGGTGGTCAAGATGTTCTCATCCACTGACCGGGCCA
TGCGCATCCGCCTCCTGCAGCAGATGGAGCAGTTCATCCAGTACCTTGACGAGCCAACAGTCAACACCCAGATCTTCCCCCACGTCGTAC
ATGGCTTCCTGGACACCAACCCTGCCATCCGGGAGCAGACGGTCAAGGGTTCAAAAAGAATTCTTCGCTCCAACGAGATCGTCCTTCCAG
CTAGTGGACTGGTGGAAACAGAGCTCCAATTAACCTTCTCCCTTCAGTACCCTCATTTCCTTAAGCGAGATGCCAACAAGCTGCAGATCA
TGCTGCAAAGGAGAAAACGTTACAAGAATCGGACCATCTTGGGCTATAAGACCTTGGCCGTGGGACTCATCAACATGGCAGAGGTGATGC
AGCATCCTAATGAAGGCGCACTGGTGCTTGGCCTACACAGCAACGTGAAGGATGTCTCTGTGCCTGTGGCAGAAATAAAGATCTACTCCC
TGTCCAGCCAACCCATTGACCATGAAGGAATCAAATCCAAGCTTTCTGATCGTTCTCCTGATATTGACAATTATTCTGAGGAAGAGGAAG
AGAGTTTCTCATCAGAACAGGAAGGCAGTGATGATCCATTGCATGGGCAGGACTTGTTCTACGAAGACGAAGATCTCCGGAAAGTGAAGA
AGACCCGGAGGAAACTAACCTCAACCTCTGCCATCACAAGGCAACCTAACATCAAACAGAAGTTTGTGGCCCTCCTGAAGCGGTTTAAAG
TTTCAGATGAGGTGGGCTTTGGGCTGGAGCATGTGTCCCGCGAGCAGATCCGGGAAGTGGAAGAGGACTTGGATGAATTGTATGACAGTC
TGGAGATGTACAACCCCAGCGACAGTGGCCCTGAGATGGAGGAGACAGAAAGCATCCTCAGCACGCCAAAGCCCAAGCTCAAGCCTTTCT
TTGAGGGGATGTCGCAGTCCAGCTCCCAGACGGAGATTGGCAGCCTCAACAGCAAAGGCAGCCTCGGAAAAGACACCACCAGCCCTATGG
AATTGGCTGCTCTAGAAAAAATTAAATCTACTTGGATTAAAAACCAAGATGACAGCTTGACTGAAACAGACACTCTGGAAATCACTGACC
AGGACATGTTTGGAGATGCCAGCACGAGTCTGGTTGTGCCGGAGAAAGTCAAAACTCCCATGAAGTCCAGTAAAACGGATCTCCAGGGCT
CTGCCTCCCCCAGCAAAGTGGAGGGGGTGCACACACCCCGGCAGAAGAGGAGCACGCCCCTGAAGGAGCGGCAGCTCTCCAAGCCCCTAA
GTGAGAGGACCAACAGTTCCGACAGCGAGCGCTCCCCAGATCTGGGCCACAGCACGCAGATTCCAAGAAAGGTGGTGTATGACCAGCTCA
ATCAGATCCTGGTGTCAGATGCAGCCCTCCCAGAAAATGTCATTCTGGTGAACACCACTGACTGGCAGGGCCAGTATGTGGCTGAGCTGC
TCCAGGACCAGCGGAAGCCTGTGGTGTGCACCTGCTCCACCGTGGAGGTCCAGGCCGTGCTGTCCGCCCTGCTCACCCGGATCCAGCGCT
ACTGCAACTGCAACTCTTCCATGCCGAGGCCAGTGAAGGTGGCTGCTGTGGGAGGCCAGAGCTACCTGAGCTCCATCCTCAGGTTCTTTG
TCAAGTCCCTGGCCAACAAGACCTCCGACTGGCTTGGCTACATGCGCTTCCTCATCATCCCCCTCGGTTCTCACCCTGTGGCCAAATACT
TGGGGTCAGTCGACAGTAAATACAGTAGTTCCTTCCTGGATTCTGGTTGGAGAGATCTGTTCAGTCGCTCGGAGCCACCAGTGTCAGAGC
AACTGGACGTGGCAGGGCGGGTGATGCAGTACGTCAACGGGGCAGCCACGACACACCAGCTTCCCGTGGCCGAAGCCATGCTGACTTGCC
GGCATAAGTTCCCTGATGAAGACTCCTATCAGAAGTTTATTCCCTTCATTGGCGTGGTGAAGGTGGGTCTGGTTGAAGACTCTCCCTCCA
CAGCAGGCGATGGGGACGATTCTCCTGTGGTCAGCCTTACTGTGCCCTCCACATCACCACCCTCCAGCTCGGGCCTGAGCCGAGACGCCA
CGGCCACCCCTCCCTCCTCCCCATCTATGAGCAGCGCCCTGGCCATCGTGGGGAGCCCTAATAGCCCATATGGGGACGTGATTGGCCTCC
AGGTGGACTACTGGCTGGGCCACCCCGGGGAGCGGAGGAGGGAAGGCGACAAGAGGGACGCCAGCTCGAAGAACACCCTCAAGAGTGTCT
TCCGCTCAGTGCAGGTGTCCCGCCTGCCCCATAGTGGGGAGGCCCAGCTTTCTGGCACCATGGCCATGACTGTGGTCACCAAAGAAAAGA
ACAAGAAAGTTCCCACCATCTTCCTGAGCAAGAAACCCCGAGAAAAGGAGGTGGATTCTAAGAGCCAGGTCATTGAAGGCATCAGCCGCC
TCATCTGCTCAGCCAAGCAGCAGCAGACTATGCTGAGAGTGTCCATCGATGGGGTCGAGTGGAGTGACATCAAGTTCTTCCAGCTGGCAG
CCCAGTGGCCCACCCATGTCAAGCACTTTCCAGTGGGACTCTTCAGTGGCAGCAAGGCCACCTGAGGCCCTGTCTCCCAGCCACTTTCCC
TCCTGGCACTGCCACCAGCCTCACCGCCTGCGGGCAGGGGGAGGCCAGCAGGCCCGGGCCCAGCACCCCTTCCCTGGCACCAGGGTCTGC
CTCTCACTCGCCCAGGTCCCGAAGGACACTGCCACAGGGACGCCTTCCCTCCCCTCCCCTCCAGCCCACCCCTGCACAGCCCCTCCTCCT
TCCCGCTTTTCCCCTTCTCCCTCCTGCTCCAGGCCCAAGGCGTGTTGGTTTTGCCTTCTGGTGCCCATAGTCCCCTGGACTGAGTCCCCC
AGGCCTTCCTTCACCCGACTTCCAAACTCTTCCTTGTGGTATCAGTTTCCTTCTCGGAAATGAGAAAGCTGGAATCCTGGTCCCCAGCAG
GAGAGCCTAGTCCTCCCCCAGCCCCTCCAGCCACCAGGGTGTCCTCTAGGATGCAGCTGCCAGATCCACTCACTCTGCTGCCTCCAGCAG
GACCCAAGGCCACTTTCAACTCTTATGGGGTTCTCCACCTGCCCCAGAGCTTCTCAAGGGAGGGTAAGGGGGCACCCTGAGCCCACAGGA
CCCCTACTTCACAGCTCACAGGGGCAGGAGGCAGCTCCCCTGCCTCCAGGACCCTGTTGCTATGGTGACACAGCGTTTCTAGGACAGAGG
GGCCTCCCAGTCTCCCCCCACCACCCGTGCACGACTTCCTCACCACCCCCAGGTTCCCTGCAGATGTCGTGTGTGTCCTGAGTGTTTCTT
TGGTTCTTTGCACGCCAAGTCTCTTGGTTGTACCATGTGACACACCCTGTGCACTGGTCGCTGTCTTCGTGGCTTCCACCCTTGTTAATG
ATGCTCCTGCCTCTGCCTCCCAGCCCCTCACCCAGCACAGCTCTGCCTGGACTTGGAGAGATGGGAGGCAGACCCCCACCACCATACATG
CTGTCTGTGGCCCCTCAGACATTCTGTTTCATCTCCCATTCATCTCCCTCCTCCCACCGTGTCAGTTTTTCTGCCTTTCCCTGCTCTGTT
CTTCCCCCTCCTTAGGCCCCAGCCTGGGCCCAGACCCATCCTCCCAGCCAGGTTTCCCTCCAGCAGGCTCCTTCCCTCCCTGTCACCTCC
CTCTCACCAACCCGGGGTCTGAGCCCCTCATTCCTGACCGTCCGTGTTCTCAGGAGTGGTTGAGGACACAGGGCCCCAGCCCAGCCCTCT
GCACCCCCCAGCCCGGCCATCTGCGCCCCACAGCCCCTTTGGAGCTTTTCTCTTGTCCTCTCACTCCTTCCCAGAAGTTTTTGCACAGAA
CTTCATTTTGAAAGTGTTTTTCTCATTCTCCATACCTCCCCCAAGCTCTCCTCCAGCCCTTCCCAGGGCTCAGCCCTGCTGTCCTGAGCG
TCTCCTGGGCCAGAGAGAGGAGATGGGGGTGGGAGGGACTGAGTTGATGTTGGGTTTTTCATTCAATAAATTGGTGATTTCTTACCGACT

>In-frame_ENST00000525364_ENST00000320580_TCGA-A6-A56B-01A_SCYL1_chr11_65300276_+_PACS1_chr11_65977833_length(amino acids)=1225AA_start in transcript=77_stop in transcript=3754
MWFFARDPVRDFPFELIPEPPEGGLPGPWALHRGRKKATGSPVSIFVYDVKPGAEEQTQVAKAAFKRFKTLRHPNILAYIDGLETEKCLH
VVTEAVTPLGIYLKARVEAGGLKELEISWGLHQIVKALSFLVNDCSLIHNNVCMAAVFVDRAGEWKLGGLDYMYSAQGNGGGPPRKGIPE
LEQYDPPELADSSGRVVREKWSADMWRLGCLIWEVFNGPLPRAAALRNPGKIPKTLVPHYCELVGANPKVRPNPARFLQNCRAPGGFMSN
RFVETNLFLEEIQIKEPAEKQKFFQELSKSLDAFPEDFCRHKVLPQLLTAFEFGNAGAVVLTPLFKVGKFLSAEEYQQKIIPVVVKMFSS
TDRAMRIRLLQQMEQFIQYLDEPTVNTQIFPHVVHGFLDTNPAIREQTVKGSKRILRSNEIVLPASGLVETELQLTFSLQYPHFLKRDAN
KLQIMLQRRKRYKNRTILGYKTLAVGLINMAEVMQHPNEGALVLGLHSNVKDVSVPVAEIKIYSLSSQPIDHEGIKSKLSDRSPDIDNYS
EEEEESFSSEQEGSDDPLHGQDLFYEDEDLRKVKKTRRKLTSTSAITRQPNIKQKFVALLKRFKVSDEVGFGLEHVSREQIREVEEDLDE
LYDSLEMYNPSDSGPEMEETESILSTPKPKLKPFFEGMSQSSSQTEIGSLNSKGSLGKDTTSPMELAALEKIKSTWIKNQDDSLTETDTL
EITDQDMFGDASTSLVVPEKVKTPMKSSKTDLQGSASPSKVEGVHTPRQKRSTPLKERQLSKPLSERTNSSDSERSPDLGHSTQIPRKVV
YDQLNQILVSDAALPENVILVNTTDWQGQYVAELLQDQRKPVVCTCSTVEVQAVLSALLTRIQRYCNCNSSMPRPVKVAAVGGQSYLSSI
LRFFVKSLANKTSDWLGYMRFLIIPLGSHPVAKYLGSVDSKYSSSFLDSGWRDLFSRSEPPVSEQLDVAGRVMQYVNGAATTHQLPVAEA
MLTCRHKFPDEDSYQKFIPFIGVVKVGLVEDSPSTAGDGDDSPVVSLTVPSTSPPSSSGLSRDATATPPSSPSMSSALAIVGSPNSPYGD
VIGLQVDYWLGHPGERRREGDKRDASSKNTLKSVFRSVQVSRLPHSGEAQLSGTMAMTVVTKEKNKKVPTIFLSKKPREKEVDSKSQVIE

--------------------------------------------------------------
>In-frame_ENST00000270176_ENST00000320580_TCGA-A6-A56B-01A_SCYL1_chr11_65300276_+_PACS1_chr11_65977833_length(transcript)=5222nt_BP=1307nt
CTCTCCGCCCCGCCCCGGCTCGGGCGGCCGGAGGACCCGGAGCTAAGGCGCCCGAACCCGCGGCGGCGGTGGGGACGATGTGGTTCTTTG
CCCGGGACCCGGTCCGGGACTTTCCGTTCGAGCTCATCCCGGAGCCCCCAGAGGGCGGCCTGCCCGGGCCCTGGGCCCTGCACCGCGGCC
GCAAGAAGGCCACAGGCAGCCCCGTGTCCATCTTCGTCTATGATGTGAAGCCTGGCGCGGAAGAGCAGACCCAGGTGGCCAAAGCTGCCT
TCAAGCGCTTCAAAACTCTACGGCACCCCAACATCCTGGCTTACATCGATGGACTGGAGACAGAAAAATGCCTCCACGTCGTGACAGAGG
CTGTGACCCCGTTGGGAATATACCTCAAGGCGAGAGTGGAGGCTGGTGGCCTGAAGGAGCTGGAGATCTCCTGGGGGCTACACCAGATCG
TGAAAGCCCTCAGCTTCCTGGTCAACGACTGCAGCCTCATCCACAACAATGTCTGCATGGCCGCCGTGTTCGTGGACCGAGCTGGCGAGT
GGAAGCTTGGGGGCCTGGACTACATGTATTCGGCCCAGGGCAACGGTGGGGGACCTCCCCGCAAGGGGATCCCCGAGCTTGAGCAGTATG
ACCCCCCGGAGTTGGCTGACAGCAGTGGCAGAGTGGTCAGAGAGAAGTGGTCAGCAGACATGTGGCGCTTGGGCTGCCTCATTTGGGAAG
TCTTCAATGGGCCCCTACCTCGGGCAGCAGCCCTACGCAACCCTGGGAAGATCCCCAAAACGCTGGTGCCCCATTACTGTGAGCTGGTGG
GAGCAAACCCCAAGGTGCGTCCCAACCCAGCCCGCTTCCTGCAGAACTGCCGGGCACCTGGTGGCTTCATGAGCAACCGCTTTGTAGAAA
CCAACCTCTTCCTGGAGGAGATTCAGATCAAAGAGCCAGCCGAGAAGCAAAAATTCTTCCAGGAGCTGAGCAAGAGCCTGGACGCATTCC
CTGAGGATTTCTGTCGGCACAAGGTGCTGCCCCAGCTGCTGACCGCCTTCGAGTTCGGCAATGCTGGGGCCGTTGTCCTCACGCCCCTCT
TCAAGGTGGGCAAGTTCCTGAGCGCTGAGGAGTATCAGCAGAAGATCATCCCTGTGGTGGTCAAGATGTTCTCATCCACTGACCGGGCCA
TGCGCATCCGCCTCCTGCAGCAGATGGAGCAGTTCATCCAGTACCTTGACGAGCCAACAGTCAACACCCAGATCTTCCCCCACGTCGTAC
ATGGCTTCCTGGACACCAACCCTGCCATCCGGGAGCAGACGGTCAAGGGTTCAAAAAGAATTCTTCGCTCCAACGAGATCGTCCTTCCAG
CTAGTGGACTGGTGGAAACAGAGCTCCAATTAACCTTCTCCCTTCAGTACCCTCATTTCCTTAAGCGAGATGCCAACAAGCTGCAGATCA
TGCTGCAAAGGAGAAAACGTTACAAGAATCGGACCATCTTGGGCTATAAGACCTTGGCCGTGGGACTCATCAACATGGCAGAGGTGATGC
AGCATCCTAATGAAGGCGCACTGGTGCTTGGCCTACACAGCAACGTGAAGGATGTCTCTGTGCCTGTGGCAGAAATAAAGATCTACTCCC
TGTCCAGCCAACCCATTGACCATGAAGGAATCAAATCCAAGCTTTCTGATCGTTCTCCTGATATTGACAATTATTCTGAGGAAGAGGAAG
AGAGTTTCTCATCAGAACAGGAAGGCAGTGATGATCCATTGCATGGGCAGGACTTGTTCTACGAAGACGAAGATCTCCGGAAAGTGAAGA
AGACCCGGAGGAAACTAACCTCAACCTCTGCCATCACAAGGCAACCTAACATCAAACAGAAGTTTGTGGCCCTCCTGAAGCGGTTTAAAG
TTTCAGATGAGGTGGGCTTTGGGCTGGAGCATGTGTCCCGCGAGCAGATCCGGGAAGTGGAAGAGGACTTGGATGAATTGTATGACAGTC
TGGAGATGTACAACCCCAGCGACAGTGGCCCTGAGATGGAGGAGACAGAAAGCATCCTCAGCACGCCAAAGCCCAAGCTCAAGCCTTTCT
TTGAGGGGATGTCGCAGTCCAGCTCCCAGACGGAGATTGGCAGCCTCAACAGCAAAGGCAGCCTCGGAAAAGACACCACCAGCCCTATGG
AATTGGCTGCTCTAGAAAAAATTAAATCTACTTGGATTAAAAACCAAGATGACAGCTTGACTGAAACAGACACTCTGGAAATCACTGACC
AGGACATGTTTGGAGATGCCAGCACGAGTCTGGTTGTGCCGGAGAAAGTCAAAACTCCCATGAAGTCCAGTAAAACGGATCTCCAGGGCT
CTGCCTCCCCCAGCAAAGTGGAGGGGGTGCACACACCCCGGCAGAAGAGGAGCACGCCCCTGAAGGAGCGGCAGCTCTCCAAGCCCCTAA
GTGAGAGGACCAACAGTTCCGACAGCGAGCGCTCCCCAGATCTGGGCCACAGCACGCAGATTCCAAGAAAGGTGGTGTATGACCAGCTCA
ATCAGATCCTGGTGTCAGATGCAGCCCTCCCAGAAAATGTCATTCTGGTGAACACCACTGACTGGCAGGGCCAGTATGTGGCTGAGCTGC
TCCAGGACCAGCGGAAGCCTGTGGTGTGCACCTGCTCCACCGTGGAGGTCCAGGCCGTGCTGTCCGCCCTGCTCACCCGGATCCAGCGCT
ACTGCAACTGCAACTCTTCCATGCCGAGGCCAGTGAAGGTGGCTGCTGTGGGAGGCCAGAGCTACCTGAGCTCCATCCTCAGGTTCTTTG
TCAAGTCCCTGGCCAACAAGACCTCCGACTGGCTTGGCTACATGCGCTTCCTCATCATCCCCCTCGGTTCTCACCCTGTGGCCAAATACT
TGGGGTCAGTCGACAGTAAATACAGTAGTTCCTTCCTGGATTCTGGTTGGAGAGATCTGTTCAGTCGCTCGGAGCCACCAGTGTCAGAGC
AACTGGACGTGGCAGGGCGGGTGATGCAGTACGTCAACGGGGCAGCCACGACACACCAGCTTCCCGTGGCCGAAGCCATGCTGACTTGCC
GGCATAAGTTCCCTGATGAAGACTCCTATCAGAAGTTTATTCCCTTCATTGGCGTGGTGAAGGTGGGTCTGGTTGAAGACTCTCCCTCCA
CAGCAGGCGATGGGGACGATTCTCCTGTGGTCAGCCTTACTGTGCCCTCCACATCACCACCCTCCAGCTCGGGCCTGAGCCGAGACGCCA
CGGCCACCCCTCCCTCCTCCCCATCTATGAGCAGCGCCCTGGCCATCGTGGGGAGCCCTAATAGCCCATATGGGGACGTGATTGGCCTCC
AGGTGGACTACTGGCTGGGCCACCCCGGGGAGCGGAGGAGGGAAGGCGACAAGAGGGACGCCAGCTCGAAGAACACCCTCAAGAGTGTCT
TCCGCTCAGTGCAGGTGTCCCGCCTGCCCCATAGTGGGGAGGCCCAGCTTTCTGGCACCATGGCCATGACTGTGGTCACCAAAGAAAAGA
ACAAGAAAGTTCCCACCATCTTCCTGAGCAAGAAACCCCGAGAAAAGGAGGTGGATTCTAAGAGCCAGGTCATTGAAGGCATCAGCCGCC
TCATCTGCTCAGCCAAGCAGCAGCAGACTATGCTGAGAGTGTCCATCGATGGGGTCGAGTGGAGTGACATCAAGTTCTTCCAGCTGGCAG
CCCAGTGGCCCACCCATGTCAAGCACTTTCCAGTGGGACTCTTCAGTGGCAGCAAGGCCACCTGAGGCCCTGTCTCCCAGCCACTTTCCC
TCCTGGCACTGCCACCAGCCTCACCGCCTGCGGGCAGGGGGAGGCCAGCAGGCCCGGGCCCAGCACCCCTTCCCTGGCACCAGGGTCTGC
CTCTCACTCGCCCAGGTCCCGAAGGACACTGCCACAGGGACGCCTTCCCTCCCCTCCCCTCCAGCCCACCCCTGCACAGCCCCTCCTCCT
TCCCGCTTTTCCCCTTCTCCCTCCTGCTCCAGGCCCAAGGCGTGTTGGTTTTGCCTTCTGGTGCCCATAGTCCCCTGGACTGAGTCCCCC
AGGCCTTCCTTCACCCGACTTCCAAACTCTTCCTTGTGGTATCAGTTTCCTTCTCGGAAATGAGAAAGCTGGAATCCTGGTCCCCAGCAG
GAGAGCCTAGTCCTCCCCCAGCCCCTCCAGCCACCAGGGTGTCCTCTAGGATGCAGCTGCCAGATCCACTCACTCTGCTGCCTCCAGCAG
GACCCAAGGCCACTTTCAACTCTTATGGGGTTCTCCACCTGCCCCAGAGCTTCTCAAGGGAGGGTAAGGGGGCACCCTGAGCCCACAGGA
CCCCTACTTCACAGCTCACAGGGGCAGGAGGCAGCTCCCCTGCCTCCAGGACCCTGTTGCTATGGTGACACAGCGTTTCTAGGACAGAGG
GGCCTCCCAGTCTCCCCCCACCACCCGTGCACGACTTCCTCACCACCCCCAGGTTCCCTGCAGATGTCGTGTGTGTCCTGAGTGTTTCTT
TGGTTCTTTGCACGCCAAGTCTCTTGGTTGTACCATGTGACACACCCTGTGCACTGGTCGCTGTCTTCGTGGCTTCCACCCTTGTTAATG
ATGCTCCTGCCTCTGCCTCCCAGCCCCTCACCCAGCACAGCTCTGCCTGGACTTGGAGAGATGGGAGGCAGACCCCCACCACCATACATG
CTGTCTGTGGCCCCTCAGACATTCTGTTTCATCTCCCATTCATCTCCCTCCTCCCACCGTGTCAGTTTTTCTGCCTTTCCCTGCTCTGTT
CTTCCCCCTCCTTAGGCCCCAGCCTGGGCCCAGACCCATCCTCCCAGCCAGGTTTCCCTCCAGCAGGCTCCTTCCCTCCCTGTCACCTCC
CTCTCACCAACCCGGGGTCTGAGCCCCTCATTCCTGACCGTCCGTGTTCTCAGGAGTGGTTGAGGACACAGGGCCCCAGCCCAGCCCTCT
GCACCCCCCAGCCCGGCCATCTGCGCCCCACAGCCCCTTTGGAGCTTTTCTCTTGTCCTCTCACTCCTTCCCAGAAGTTTTTGCACAGAA
CTTCATTTTGAAAGTGTTTTTCTCATTCTCCATACCTCCCCCAAGCTCTCCTCCAGCCCTTCCCAGGGCTCAGCCCTGCTGTCCTGAGCG
TCTCCTGGGCCAGAGAGAGGAGATGGGGGTGGGAGGGACTGAGTTGATGTTGGGTTTTTCATTCAATAAATTGGTGATTTCTTACCGACT

>In-frame_ENST00000270176_ENST00000320580_TCGA-A6-A56B-01A_SCYL1_chr11_65300276_+_PACS1_chr11_65977833_length(amino acids)=1225AA_start in transcript=77_stop in transcript=3754
MWFFARDPVRDFPFELIPEPPEGGLPGPWALHRGRKKATGSPVSIFVYDVKPGAEEQTQVAKAAFKRFKTLRHPNILAYIDGLETEKCLH
VVTEAVTPLGIYLKARVEAGGLKELEISWGLHQIVKALSFLVNDCSLIHNNVCMAAVFVDRAGEWKLGGLDYMYSAQGNGGGPPRKGIPE
LEQYDPPELADSSGRVVREKWSADMWRLGCLIWEVFNGPLPRAAALRNPGKIPKTLVPHYCELVGANPKVRPNPARFLQNCRAPGGFMSN
RFVETNLFLEEIQIKEPAEKQKFFQELSKSLDAFPEDFCRHKVLPQLLTAFEFGNAGAVVLTPLFKVGKFLSAEEYQQKIIPVVVKMFSS
TDRAMRIRLLQQMEQFIQYLDEPTVNTQIFPHVVHGFLDTNPAIREQTVKGSKRILRSNEIVLPASGLVETELQLTFSLQYPHFLKRDAN
KLQIMLQRRKRYKNRTILGYKTLAVGLINMAEVMQHPNEGALVLGLHSNVKDVSVPVAEIKIYSLSSQPIDHEGIKSKLSDRSPDIDNYS
EEEEESFSSEQEGSDDPLHGQDLFYEDEDLRKVKKTRRKLTSTSAITRQPNIKQKFVALLKRFKVSDEVGFGLEHVSREQIREVEEDLDE
LYDSLEMYNPSDSGPEMEETESILSTPKPKLKPFFEGMSQSSSQTEIGSLNSKGSLGKDTTSPMELAALEKIKSTWIKNQDDSLTETDTL
EITDQDMFGDASTSLVVPEKVKTPMKSSKTDLQGSASPSKVEGVHTPRQKRSTPLKERQLSKPLSERTNSSDSERSPDLGHSTQIPRKVV
YDQLNQILVSDAALPENVILVNTTDWQGQYVAELLQDQRKPVVCTCSTVEVQAVLSALLTRIQRYCNCNSSMPRPVKVAAVGGQSYLSSI
LRFFVKSLANKTSDWLGYMRFLIIPLGSHPVAKYLGSVDSKYSSSFLDSGWRDLFSRSEPPVSEQLDVAGRVMQYVNGAATTHQLPVAEA
MLTCRHKFPDEDSYQKFIPFIGVVKVGLVEDSPSTAGDGDDSPVVSLTVPSTSPPSSSGLSRDATATPPSSPSMSSALAIVGSPNSPYGD
VIGLQVDYWLGHPGERRREGDKRDASSKNTLKSVFRSVQVSRLPHSGEAQLSGTMAMTVVTKEKNKKVPTIFLSKKPREKEVDSKSQVIE

--------------------------------------------------------------
>In-frame_ENST00000420247_ENST00000320580_TCGA-A6-A56B-01A_SCYL1_chr11_65300276_+_PACS1_chr11_65977833_length(transcript)=5214nt_BP=1299nt
CCCGCCCCGGCTCGGGCGGCCGGAGGACCCGGAGCTAAGGCGCCCGAACCCGCGGCGGCGGTGGGGACGATGTGGTTCTTTGCCCGGGAC
CCGGTCCGGGACTTTCCGTTCGAGCTCATCCCGGAGCCCCCAGAGGGCGGCCTGCCCGGGCCCTGGGCCCTGCACCGCGGCCGCAAGAAG
GCCACAGGCAGCCCCGTGTCCATCTTCGTCTATGATGTGAAGCCTGGCGCGGAAGAGCAGACCCAGGTGGCCAAAGCTGCCTTCAAGCGC
TTCAAAACTCTACGGCACCCCAACATCCTGGCTTACATCGATGGACTGGAGACAGAAAAATGCCTCCACGTCGTGACAGAGGCTGTGACC
CCGTTGGGAATATACCTCAAGGCGAGAGTGGAGGCTGGTGGCCTGAAGGAGCTGGAGATCTCCTGGGGGCTACACCAGATCGTGAAAGCC
CTCAGCTTCCTGGTCAACGACTGCAGCCTCATCCACAACAATGTCTGCATGGCCGCCGTGTTCGTGGACCGAGCTGGCGAGTGGAAGCTT
GGGGGCCTGGACTACATGTATTCGGCCCAGGGCAACGGTGGGGGACCTCCCCGCAAGGGGATCCCCGAGCTTGAGCAGTATGACCCCCCG
GAGTTGGCTGACAGCAGTGGCAGAGTGGTCAGAGAGAAGTGGTCAGCAGACATGTGGCGCTTGGGCTGCCTCATTTGGGAAGTCTTCAAT
GGGCCCCTACCTCGGGCAGCAGCCCTACGCAACCCTGGGAAGATCCCCAAAACGCTGGTGCCCCATTACTGTGAGCTGGTGGGAGCAAAC
CCCAAGGTGCGTCCCAACCCAGCCCGCTTCCTGCAGAACTGCCGGGCACCTGGTGGCTTCATGAGCAACCGCTTTGTAGAAACCAACCTC
TTCCTGGAGGAGATTCAGATCAAAGAGCCAGCCGAGAAGCAAAAATTCTTCCAGGAGCTGAGCAAGAGCCTGGACGCATTCCCTGAGGAT
TTCTGTCGGCACAAGGTGCTGCCCCAGCTGCTGACCGCCTTCGAGTTCGGCAATGCTGGGGCCGTTGTCCTCACGCCCCTCTTCAAGGTG
GGCAAGTTCCTGAGCGCTGAGGAGTATCAGCAGAAGATCATCCCTGTGGTGGTCAAGATGTTCTCATCCACTGACCGGGCCATGCGCATC
CGCCTCCTGCAGCAGATGGAGCAGTTCATCCAGTACCTTGACGAGCCAACAGTCAACACCCAGATCTTCCCCCACGTCGTACATGGCTTC
CTGGACACCAACCCTGCCATCCGGGAGCAGACGGTCAAGGGTTCAAAAAGAATTCTTCGCTCCAACGAGATCGTCCTTCCAGCTAGTGGA
CTGGTGGAAACAGAGCTCCAATTAACCTTCTCCCTTCAGTACCCTCATTTCCTTAAGCGAGATGCCAACAAGCTGCAGATCATGCTGCAA
AGGAGAAAACGTTACAAGAATCGGACCATCTTGGGCTATAAGACCTTGGCCGTGGGACTCATCAACATGGCAGAGGTGATGCAGCATCCT
AATGAAGGCGCACTGGTGCTTGGCCTACACAGCAACGTGAAGGATGTCTCTGTGCCTGTGGCAGAAATAAAGATCTACTCCCTGTCCAGC
CAACCCATTGACCATGAAGGAATCAAATCCAAGCTTTCTGATCGTTCTCCTGATATTGACAATTATTCTGAGGAAGAGGAAGAGAGTTTC
TCATCAGAACAGGAAGGCAGTGATGATCCATTGCATGGGCAGGACTTGTTCTACGAAGACGAAGATCTCCGGAAAGTGAAGAAGACCCGG
AGGAAACTAACCTCAACCTCTGCCATCACAAGGCAACCTAACATCAAACAGAAGTTTGTGGCCCTCCTGAAGCGGTTTAAAGTTTCAGAT
GAGGTGGGCTTTGGGCTGGAGCATGTGTCCCGCGAGCAGATCCGGGAAGTGGAAGAGGACTTGGATGAATTGTATGACAGTCTGGAGATG
TACAACCCCAGCGACAGTGGCCCTGAGATGGAGGAGACAGAAAGCATCCTCAGCACGCCAAAGCCCAAGCTCAAGCCTTTCTTTGAGGGG
ATGTCGCAGTCCAGCTCCCAGACGGAGATTGGCAGCCTCAACAGCAAAGGCAGCCTCGGAAAAGACACCACCAGCCCTATGGAATTGGCT
GCTCTAGAAAAAATTAAATCTACTTGGATTAAAAACCAAGATGACAGCTTGACTGAAACAGACACTCTGGAAATCACTGACCAGGACATG
TTTGGAGATGCCAGCACGAGTCTGGTTGTGCCGGAGAAAGTCAAAACTCCCATGAAGTCCAGTAAAACGGATCTCCAGGGCTCTGCCTCC
CCCAGCAAAGTGGAGGGGGTGCACACACCCCGGCAGAAGAGGAGCACGCCCCTGAAGGAGCGGCAGCTCTCCAAGCCCCTAAGTGAGAGG
ACCAACAGTTCCGACAGCGAGCGCTCCCCAGATCTGGGCCACAGCACGCAGATTCCAAGAAAGGTGGTGTATGACCAGCTCAATCAGATC
CTGGTGTCAGATGCAGCCCTCCCAGAAAATGTCATTCTGGTGAACACCACTGACTGGCAGGGCCAGTATGTGGCTGAGCTGCTCCAGGAC
CAGCGGAAGCCTGTGGTGTGCACCTGCTCCACCGTGGAGGTCCAGGCCGTGCTGTCCGCCCTGCTCACCCGGATCCAGCGCTACTGCAAC
TGCAACTCTTCCATGCCGAGGCCAGTGAAGGTGGCTGCTGTGGGAGGCCAGAGCTACCTGAGCTCCATCCTCAGGTTCTTTGTCAAGTCC
CTGGCCAACAAGACCTCCGACTGGCTTGGCTACATGCGCTTCCTCATCATCCCCCTCGGTTCTCACCCTGTGGCCAAATACTTGGGGTCA
GTCGACAGTAAATACAGTAGTTCCTTCCTGGATTCTGGTTGGAGAGATCTGTTCAGTCGCTCGGAGCCACCAGTGTCAGAGCAACTGGAC
GTGGCAGGGCGGGTGATGCAGTACGTCAACGGGGCAGCCACGACACACCAGCTTCCCGTGGCCGAAGCCATGCTGACTTGCCGGCATAAG
TTCCCTGATGAAGACTCCTATCAGAAGTTTATTCCCTTCATTGGCGTGGTGAAGGTGGGTCTGGTTGAAGACTCTCCCTCCACAGCAGGC
GATGGGGACGATTCTCCTGTGGTCAGCCTTACTGTGCCCTCCACATCACCACCCTCCAGCTCGGGCCTGAGCCGAGACGCCACGGCCACC
CCTCCCTCCTCCCCATCTATGAGCAGCGCCCTGGCCATCGTGGGGAGCCCTAATAGCCCATATGGGGACGTGATTGGCCTCCAGGTGGAC
TACTGGCTGGGCCACCCCGGGGAGCGGAGGAGGGAAGGCGACAAGAGGGACGCCAGCTCGAAGAACACCCTCAAGAGTGTCTTCCGCTCA
GTGCAGGTGTCCCGCCTGCCCCATAGTGGGGAGGCCCAGCTTTCTGGCACCATGGCCATGACTGTGGTCACCAAAGAAAAGAACAAGAAA
GTTCCCACCATCTTCCTGAGCAAGAAACCCCGAGAAAAGGAGGTGGATTCTAAGAGCCAGGTCATTGAAGGCATCAGCCGCCTCATCTGC
TCAGCCAAGCAGCAGCAGACTATGCTGAGAGTGTCCATCGATGGGGTCGAGTGGAGTGACATCAAGTTCTTCCAGCTGGCAGCCCAGTGG
CCCACCCATGTCAAGCACTTTCCAGTGGGACTCTTCAGTGGCAGCAAGGCCACCTGAGGCCCTGTCTCCCAGCCACTTTCCCTCCTGGCA
CTGCCACCAGCCTCACCGCCTGCGGGCAGGGGGAGGCCAGCAGGCCCGGGCCCAGCACCCCTTCCCTGGCACCAGGGTCTGCCTCTCACT
CGCCCAGGTCCCGAAGGACACTGCCACAGGGACGCCTTCCCTCCCCTCCCCTCCAGCCCACCCCTGCACAGCCCCTCCTCCTTCCCGCTT
TTCCCCTTCTCCCTCCTGCTCCAGGCCCAAGGCGTGTTGGTTTTGCCTTCTGGTGCCCATAGTCCCCTGGACTGAGTCCCCCAGGCCTTC
CTTCACCCGACTTCCAAACTCTTCCTTGTGGTATCAGTTTCCTTCTCGGAAATGAGAAAGCTGGAATCCTGGTCCCCAGCAGGAGAGCCT
AGTCCTCCCCCAGCCCCTCCAGCCACCAGGGTGTCCTCTAGGATGCAGCTGCCAGATCCACTCACTCTGCTGCCTCCAGCAGGACCCAAG
GCCACTTTCAACTCTTATGGGGTTCTCCACCTGCCCCAGAGCTTCTCAAGGGAGGGTAAGGGGGCACCCTGAGCCCACAGGACCCCTACT
TCACAGCTCACAGGGGCAGGAGGCAGCTCCCCTGCCTCCAGGACCCTGTTGCTATGGTGACACAGCGTTTCTAGGACAGAGGGGCCTCCC
AGTCTCCCCCCACCACCCGTGCACGACTTCCTCACCACCCCCAGGTTCCCTGCAGATGTCGTGTGTGTCCTGAGTGTTTCTTTGGTTCTT
TGCACGCCAAGTCTCTTGGTTGTACCATGTGACACACCCTGTGCACTGGTCGCTGTCTTCGTGGCTTCCACCCTTGTTAATGATGCTCCT
GCCTCTGCCTCCCAGCCCCTCACCCAGCACAGCTCTGCCTGGACTTGGAGAGATGGGAGGCAGACCCCCACCACCATACATGCTGTCTGT
GGCCCCTCAGACATTCTGTTTCATCTCCCATTCATCTCCCTCCTCCCACCGTGTCAGTTTTTCTGCCTTTCCCTGCTCTGTTCTTCCCCC
TCCTTAGGCCCCAGCCTGGGCCCAGACCCATCCTCCCAGCCAGGTTTCCCTCCAGCAGGCTCCTTCCCTCCCTGTCACCTCCCTCTCACC
AACCCGGGGTCTGAGCCCCTCATTCCTGACCGTCCGTGTTCTCAGGAGTGGTTGAGGACACAGGGCCCCAGCCCAGCCCTCTGCACCCCC
CAGCCCGGCCATCTGCGCCCCACAGCCCCTTTGGAGCTTTTCTCTTGTCCTCTCACTCCTTCCCAGAAGTTTTTGCACAGAACTTCATTT
TGAAAGTGTTTTTCTCATTCTCCATACCTCCCCCAAGCTCTCCTCCAGCCCTTCCCAGGGCTCAGCCCTGCTGTCCTGAGCGTCTCCTGG

>In-frame_ENST00000420247_ENST00000320580_TCGA-A6-A56B-01A_SCYL1_chr11_65300276_+_PACS1_chr11_65977833_length(amino acids)=1225AA_start in transcript=69_stop in transcript=3746
MWFFARDPVRDFPFELIPEPPEGGLPGPWALHRGRKKATGSPVSIFVYDVKPGAEEQTQVAKAAFKRFKTLRHPNILAYIDGLETEKCLH
VVTEAVTPLGIYLKARVEAGGLKELEISWGLHQIVKALSFLVNDCSLIHNNVCMAAVFVDRAGEWKLGGLDYMYSAQGNGGGPPRKGIPE
LEQYDPPELADSSGRVVREKWSADMWRLGCLIWEVFNGPLPRAAALRNPGKIPKTLVPHYCELVGANPKVRPNPARFLQNCRAPGGFMSN
RFVETNLFLEEIQIKEPAEKQKFFQELSKSLDAFPEDFCRHKVLPQLLTAFEFGNAGAVVLTPLFKVGKFLSAEEYQQKIIPVVVKMFSS
TDRAMRIRLLQQMEQFIQYLDEPTVNTQIFPHVVHGFLDTNPAIREQTVKGSKRILRSNEIVLPASGLVETELQLTFSLQYPHFLKRDAN
KLQIMLQRRKRYKNRTILGYKTLAVGLINMAEVMQHPNEGALVLGLHSNVKDVSVPVAEIKIYSLSSQPIDHEGIKSKLSDRSPDIDNYS
EEEEESFSSEQEGSDDPLHGQDLFYEDEDLRKVKKTRRKLTSTSAITRQPNIKQKFVALLKRFKVSDEVGFGLEHVSREQIREVEEDLDE
LYDSLEMYNPSDSGPEMEETESILSTPKPKLKPFFEGMSQSSSQTEIGSLNSKGSLGKDTTSPMELAALEKIKSTWIKNQDDSLTETDTL
EITDQDMFGDASTSLVVPEKVKTPMKSSKTDLQGSASPSKVEGVHTPRQKRSTPLKERQLSKPLSERTNSSDSERSPDLGHSTQIPRKVV
YDQLNQILVSDAALPENVILVNTTDWQGQYVAELLQDQRKPVVCTCSTVEVQAVLSALLTRIQRYCNCNSSMPRPVKVAAVGGQSYLSSI
LRFFVKSLANKTSDWLGYMRFLIIPLGSHPVAKYLGSVDSKYSSSFLDSGWRDLFSRSEPPVSEQLDVAGRVMQYVNGAATTHQLPVAEA
MLTCRHKFPDEDSYQKFIPFIGVVKVGLVEDSPSTAGDGDDSPVVSLTVPSTSPPSSSGLSRDATATPPSSPSMSSALAIVGSPNSPYGD
VIGLQVDYWLGHPGERRREGDKRDASSKNTLKSVFRSVQVSRLPHSGEAQLSGTMAMTVVTKEKNKKVPTIFLSKKPREKEVDSKSQVIE

--------------------------------------------------------------
>In-frame_ENST00000533862_ENST00000320580_TCGA-A6-A56B-01A_SCYL1_chr11_65300276_+_PACS1_chr11_65977833_length(transcript)=5187nt_BP=1272nt
CCCGGAGCTAAGGCGCCCGAACCCGCGGCGGCGGTGGGGACGATGTGGTTCTTTGCCCGGGACCCGGTCCGGGACTTTCCGTTCGAGCTC
ATCCCGGAGCCCCCAGAGGGCGGCCTGCCCGGGCCCTGGGCCCTGCACCGCGGCCGCAAGAAGGCCACAGGCAGCCCCGTGTCCATCTTC
GTCTATGATGTGAAGCCTGGCGCGGAAGAGCAGACCCAGGTGGCCAAAGCTGCCTTCAAGCGCTTCAAAACTCTACGGCACCCCAACATC
CTGGCTTACATCGATGGACTGGAGACAGAAAAATGCCTCCACGTCGTGACAGAGGCTGTGACCCCGTTGGGAATATACCTCAAGGCGAGA
GTGGAGGCTGGTGGCCTGAAGGAGCTGGAGATCTCCTGGGGGCTACACCAGATCGTGAAAGCCCTCAGCTTCCTGGTCAACGACTGCAGC
CTCATCCACAACAATGTCTGCATGGCCGCCGTGTTCGTGGACCGAGCTGGCGAGTGGAAGCTTGGGGGCCTGGACTACATGTATTCGGCC
CAGGGCAACGGTGGGGGACCTCCCCGCAAGGGGATCCCCGAGCTTGAGCAGTATGACCCCCCGGAGTTGGCTGACAGCAGTGGCAGAGTG
GTCAGAGAGAAGTGGTCAGCAGACATGTGGCGCTTGGGCTGCCTCATTTGGGAAGTCTTCAATGGGCCCCTACCTCGGGCAGCAGCCCTA
CGCAACCCTGGGAAGATCCCCAAAACGCTGGTGCCCCATTACTGTGAGCTGGTGGGAGCAAACCCCAAGGTGCGTCCCAACCCAGCCCGC
TTCCTGCAGAACTGCCGGGCACCTGGTGGCTTCATGAGCAACCGCTTTGTAGAAACCAACCTCTTCCTGGAGGAGATTCAGATCAAAGAG
CCAGCCGAGAAGCAAAAATTCTTCCAGGAGCTGAGCAAGAGCCTGGACGCATTCCCTGAGGATTTCTGTCGGCACAAGGTGCTGCCCCAG
CTGCTGACCGCCTTCGAGTTCGGCAATGCTGGGGCCGTTGTCCTCACGCCCCTCTTCAAGGTGGGCAAGTTCCTGAGCGCTGAGGAGTAT
CAGCAGAAGATCATCCCTGTGGTGGTCAAGATGTTCTCATCCACTGACCGGGCCATGCGCATCCGCCTCCTGCAGCAGATGGAGCAGTTC
ATCCAGTACCTTGACGAGCCAACAGTCAACACCCAGATCTTCCCCCACGTCGTACATGGCTTCCTGGACACCAACCCTGCCATCCGGGAG
CAGACGGTCAAGGGTTCAAAAAGAATTCTTCGCTCCAACGAGATCGTCCTTCCAGCTAGTGGACTGGTGGAAACAGAGCTCCAATTAACC
TTCTCCCTTCAGTACCCTCATTTCCTTAAGCGAGATGCCAACAAGCTGCAGATCATGCTGCAAAGGAGAAAACGTTACAAGAATCGGACC
ATCTTGGGCTATAAGACCTTGGCCGTGGGACTCATCAACATGGCAGAGGTGATGCAGCATCCTAATGAAGGCGCACTGGTGCTTGGCCTA
CACAGCAACGTGAAGGATGTCTCTGTGCCTGTGGCAGAAATAAAGATCTACTCCCTGTCCAGCCAACCCATTGACCATGAAGGAATCAAA
TCCAAGCTTTCTGATCGTTCTCCTGATATTGACAATTATTCTGAGGAAGAGGAAGAGAGTTTCTCATCAGAACAGGAAGGCAGTGATGAT
CCATTGCATGGGCAGGACTTGTTCTACGAAGACGAAGATCTCCGGAAAGTGAAGAAGACCCGGAGGAAACTAACCTCAACCTCTGCCATC
ACAAGGCAACCTAACATCAAACAGAAGTTTGTGGCCCTCCTGAAGCGGTTTAAAGTTTCAGATGAGGTGGGCTTTGGGCTGGAGCATGTG
TCCCGCGAGCAGATCCGGGAAGTGGAAGAGGACTTGGATGAATTGTATGACAGTCTGGAGATGTACAACCCCAGCGACAGTGGCCCTGAG
ATGGAGGAGACAGAAAGCATCCTCAGCACGCCAAAGCCCAAGCTCAAGCCTTTCTTTGAGGGGATGTCGCAGTCCAGCTCCCAGACGGAG
ATTGGCAGCCTCAACAGCAAAGGCAGCCTCGGAAAAGACACCACCAGCCCTATGGAATTGGCTGCTCTAGAAAAAATTAAATCTACTTGG
ATTAAAAACCAAGATGACAGCTTGACTGAAACAGACACTCTGGAAATCACTGACCAGGACATGTTTGGAGATGCCAGCACGAGTCTGGTT
GTGCCGGAGAAAGTCAAAACTCCCATGAAGTCCAGTAAAACGGATCTCCAGGGCTCTGCCTCCCCCAGCAAAGTGGAGGGGGTGCACACA
CCCCGGCAGAAGAGGAGCACGCCCCTGAAGGAGCGGCAGCTCTCCAAGCCCCTAAGTGAGAGGACCAACAGTTCCGACAGCGAGCGCTCC
CCAGATCTGGGCCACAGCACGCAGATTCCAAGAAAGGTGGTGTATGACCAGCTCAATCAGATCCTGGTGTCAGATGCAGCCCTCCCAGAA
AATGTCATTCTGGTGAACACCACTGACTGGCAGGGCCAGTATGTGGCTGAGCTGCTCCAGGACCAGCGGAAGCCTGTGGTGTGCACCTGC
TCCACCGTGGAGGTCCAGGCCGTGCTGTCCGCCCTGCTCACCCGGATCCAGCGCTACTGCAACTGCAACTCTTCCATGCCGAGGCCAGTG
AAGGTGGCTGCTGTGGGAGGCCAGAGCTACCTGAGCTCCATCCTCAGGTTCTTTGTCAAGTCCCTGGCCAACAAGACCTCCGACTGGCTT
GGCTACATGCGCTTCCTCATCATCCCCCTCGGTTCTCACCCTGTGGCCAAATACTTGGGGTCAGTCGACAGTAAATACAGTAGTTCCTTC
CTGGATTCTGGTTGGAGAGATCTGTTCAGTCGCTCGGAGCCACCAGTGTCAGAGCAACTGGACGTGGCAGGGCGGGTGATGCAGTACGTC
AACGGGGCAGCCACGACACACCAGCTTCCCGTGGCCGAAGCCATGCTGACTTGCCGGCATAAGTTCCCTGATGAAGACTCCTATCAGAAG
TTTATTCCCTTCATTGGCGTGGTGAAGGTGGGTCTGGTTGAAGACTCTCCCTCCACAGCAGGCGATGGGGACGATTCTCCTGTGGTCAGC
CTTACTGTGCCCTCCACATCACCACCCTCCAGCTCGGGCCTGAGCCGAGACGCCACGGCCACCCCTCCCTCCTCCCCATCTATGAGCAGC
GCCCTGGCCATCGTGGGGAGCCCTAATAGCCCATATGGGGACGTGATTGGCCTCCAGGTGGACTACTGGCTGGGCCACCCCGGGGAGCGG
AGGAGGGAAGGCGACAAGAGGGACGCCAGCTCGAAGAACACCCTCAAGAGTGTCTTCCGCTCAGTGCAGGTGTCCCGCCTGCCCCATAGT
GGGGAGGCCCAGCTTTCTGGCACCATGGCCATGACTGTGGTCACCAAAGAAAAGAACAAGAAAGTTCCCACCATCTTCCTGAGCAAGAAA
CCCCGAGAAAAGGAGGTGGATTCTAAGAGCCAGGTCATTGAAGGCATCAGCCGCCTCATCTGCTCAGCCAAGCAGCAGCAGACTATGCTG
AGAGTGTCCATCGATGGGGTCGAGTGGAGTGACATCAAGTTCTTCCAGCTGGCAGCCCAGTGGCCCACCCATGTCAAGCACTTTCCAGTG
GGACTCTTCAGTGGCAGCAAGGCCACCTGAGGCCCTGTCTCCCAGCCACTTTCCCTCCTGGCACTGCCACCAGCCTCACCGCCTGCGGGC
AGGGGGAGGCCAGCAGGCCCGGGCCCAGCACCCCTTCCCTGGCACCAGGGTCTGCCTCTCACTCGCCCAGGTCCCGAAGGACACTGCCAC
AGGGACGCCTTCCCTCCCCTCCCCTCCAGCCCACCCCTGCACAGCCCCTCCTCCTTCCCGCTTTTCCCCTTCTCCCTCCTGCTCCAGGCC
CAAGGCGTGTTGGTTTTGCCTTCTGGTGCCCATAGTCCCCTGGACTGAGTCCCCCAGGCCTTCCTTCACCCGACTTCCAAACTCTTCCTT
GTGGTATCAGTTTCCTTCTCGGAAATGAGAAAGCTGGAATCCTGGTCCCCAGCAGGAGAGCCTAGTCCTCCCCCAGCCCCTCCAGCCACC
AGGGTGTCCTCTAGGATGCAGCTGCCAGATCCACTCACTCTGCTGCCTCCAGCAGGACCCAAGGCCACTTTCAACTCTTATGGGGTTCTC
CACCTGCCCCAGAGCTTCTCAAGGGAGGGTAAGGGGGCACCCTGAGCCCACAGGACCCCTACTTCACAGCTCACAGGGGCAGGAGGCAGC
TCCCCTGCCTCCAGGACCCTGTTGCTATGGTGACACAGCGTTTCTAGGACAGAGGGGCCTCCCAGTCTCCCCCCACCACCCGTGCACGAC
TTCCTCACCACCCCCAGGTTCCCTGCAGATGTCGTGTGTGTCCTGAGTGTTTCTTTGGTTCTTTGCACGCCAAGTCTCTTGGTTGTACCA
TGTGACACACCCTGTGCACTGGTCGCTGTCTTCGTGGCTTCCACCCTTGTTAATGATGCTCCTGCCTCTGCCTCCCAGCCCCTCACCCAG
CACAGCTCTGCCTGGACTTGGAGAGATGGGAGGCAGACCCCCACCACCATACATGCTGTCTGTGGCCCCTCAGACATTCTGTTTCATCTC
CCATTCATCTCCCTCCTCCCACCGTGTCAGTTTTTCTGCCTTTCCCTGCTCTGTTCTTCCCCCTCCTTAGGCCCCAGCCTGGGCCCAGAC
CCATCCTCCCAGCCAGGTTTCCCTCCAGCAGGCTCCTTCCCTCCCTGTCACCTCCCTCTCACCAACCCGGGGTCTGAGCCCCTCATTCCT
GACCGTCCGTGTTCTCAGGAGTGGTTGAGGACACAGGGCCCCAGCCCAGCCCTCTGCACCCCCCAGCCCGGCCATCTGCGCCCCACAGCC
CCTTTGGAGCTTTTCTCTTGTCCTCTCACTCCTTCCCAGAAGTTTTTGCACAGAACTTCATTTTGAAAGTGTTTTTCTCATTCTCCATAC
CTCCCCCAAGCTCTCCTCCAGCCCTTCCCAGGGCTCAGCCCTGCTGTCCTGAGCGTCTCCTGGGCCAGAGAGAGGAGATGGGGGTGGGAG

>In-frame_ENST00000533862_ENST00000320580_TCGA-A6-A56B-01A_SCYL1_chr11_65300276_+_PACS1_chr11_65977833_length(amino acids)=1225AA_start in transcript=42_stop in transcript=3719
MWFFARDPVRDFPFELIPEPPEGGLPGPWALHRGRKKATGSPVSIFVYDVKPGAEEQTQVAKAAFKRFKTLRHPNILAYIDGLETEKCLH
VVTEAVTPLGIYLKARVEAGGLKELEISWGLHQIVKALSFLVNDCSLIHNNVCMAAVFVDRAGEWKLGGLDYMYSAQGNGGGPPRKGIPE
LEQYDPPELADSSGRVVREKWSADMWRLGCLIWEVFNGPLPRAAALRNPGKIPKTLVPHYCELVGANPKVRPNPARFLQNCRAPGGFMSN
RFVETNLFLEEIQIKEPAEKQKFFQELSKSLDAFPEDFCRHKVLPQLLTAFEFGNAGAVVLTPLFKVGKFLSAEEYQQKIIPVVVKMFSS
TDRAMRIRLLQQMEQFIQYLDEPTVNTQIFPHVVHGFLDTNPAIREQTVKGSKRILRSNEIVLPASGLVETELQLTFSLQYPHFLKRDAN
KLQIMLQRRKRYKNRTILGYKTLAVGLINMAEVMQHPNEGALVLGLHSNVKDVSVPVAEIKIYSLSSQPIDHEGIKSKLSDRSPDIDNYS
EEEEESFSSEQEGSDDPLHGQDLFYEDEDLRKVKKTRRKLTSTSAITRQPNIKQKFVALLKRFKVSDEVGFGLEHVSREQIREVEEDLDE
LYDSLEMYNPSDSGPEMEETESILSTPKPKLKPFFEGMSQSSSQTEIGSLNSKGSLGKDTTSPMELAALEKIKSTWIKNQDDSLTETDTL
EITDQDMFGDASTSLVVPEKVKTPMKSSKTDLQGSASPSKVEGVHTPRQKRSTPLKERQLSKPLSERTNSSDSERSPDLGHSTQIPRKVV
YDQLNQILVSDAALPENVILVNTTDWQGQYVAELLQDQRKPVVCTCSTVEVQAVLSALLTRIQRYCNCNSSMPRPVKVAAVGGQSYLSSI
LRFFVKSLANKTSDWLGYMRFLIIPLGSHPVAKYLGSVDSKYSSSFLDSGWRDLFSRSEPPVSEQLDVAGRVMQYVNGAATTHQLPVAEA
MLTCRHKFPDEDSYQKFIPFIGVVKVGLVEDSPSTAGDGDDSPVVSLTVPSTSPPSSSGLSRDATATPPSSPSMSSALAIVGSPNSPYGD
VIGLQVDYWLGHPGERRREGDKRDASSKNTLKSVFRSVQVSRLPHSGEAQLSGTMAMTVVTKEKNKKVPTIFLSKKPREKEVDSKSQVIE

--------------------------------------------------------------
>In-frame_ENST00000279270_ENST00000320580_TCGA-A6-A56B-01A_SCYL1_chr11_65300276_+_PACS1_chr11_65977833_length(transcript)=5186nt_BP=1271nt
CCGGAGCTAAGGCGCCCGAACCCGCGGCGGCGGTGGGGACGATGTGGTTCTTTGCCCGGGACCCGGTCCGGGACTTTCCGTTCGAGCTCA
TCCCGGAGCCCCCAGAGGGCGGCCTGCCCGGGCCCTGGGCCCTGCACCGCGGCCGCAAGAAGGCCACAGGCAGCCCCGTGTCCATCTTCG
TCTATGATGTGAAGCCTGGCGCGGAAGAGCAGACCCAGGTGGCCAAAGCTGCCTTCAAGCGCTTCAAAACTCTACGGCACCCCAACATCC
TGGCTTACATCGATGGACTGGAGACAGAAAAATGCCTCCACGTCGTGACAGAGGCTGTGACCCCGTTGGGAATATACCTCAAGGCGAGAG
TGGAGGCTGGTGGCCTGAAGGAGCTGGAGATCTCCTGGGGGCTACACCAGATCGTGAAAGCCCTCAGCTTCCTGGTCAACGACTGCAGCC
TCATCCACAACAATGTCTGCATGGCCGCCGTGTTCGTGGACCGAGCTGGCGAGTGGAAGCTTGGGGGCCTGGACTACATGTATTCGGCCC
AGGGCAACGGTGGGGGACCTCCCCGCAAGGGGATCCCCGAGCTTGAGCAGTATGACCCCCCGGAGTTGGCTGACAGCAGTGGCAGAGTGG
TCAGAGAGAAGTGGTCAGCAGACATGTGGCGCTTGGGCTGCCTCATTTGGGAAGTCTTCAATGGGCCCCTACCTCGGGCAGCAGCCCTAC
GCAACCCTGGGAAGATCCCCAAAACGCTGGTGCCCCATTACTGTGAGCTGGTGGGAGCAAACCCCAAGGTGCGTCCCAACCCAGCCCGCT
TCCTGCAGAACTGCCGGGCACCTGGTGGCTTCATGAGCAACCGCTTTGTAGAAACCAACCTCTTCCTGGAGGAGATTCAGATCAAAGAGC
CAGCCGAGAAGCAAAAATTCTTCCAGGAGCTGAGCAAGAGCCTGGACGCATTCCCTGAGGATTTCTGTCGGCACAAGGTGCTGCCCCAGC
TGCTGACCGCCTTCGAGTTCGGCAATGCTGGGGCCGTTGTCCTCACGCCCCTCTTCAAGGTGGGCAAGTTCCTGAGCGCTGAGGAGTATC
AGCAGAAGATCATCCCTGTGGTGGTCAAGATGTTCTCATCCACTGACCGGGCCATGCGCATCCGCCTCCTGCAGCAGATGGAGCAGTTCA
TCCAGTACCTTGACGAGCCAACAGTCAACACCCAGATCTTCCCCCACGTCGTACATGGCTTCCTGGACACCAACCCTGCCATCCGGGAGC
AGACGGTCAAGGGTTCAAAAAGAATTCTTCGCTCCAACGAGATCGTCCTTCCAGCTAGTGGACTGGTGGAAACAGAGCTCCAATTAACCT
TCTCCCTTCAGTACCCTCATTTCCTTAAGCGAGATGCCAACAAGCTGCAGATCATGCTGCAAAGGAGAAAACGTTACAAGAATCGGACCA
TCTTGGGCTATAAGACCTTGGCCGTGGGACTCATCAACATGGCAGAGGTGATGCAGCATCCTAATGAAGGCGCACTGGTGCTTGGCCTAC
ACAGCAACGTGAAGGATGTCTCTGTGCCTGTGGCAGAAATAAAGATCTACTCCCTGTCCAGCCAACCCATTGACCATGAAGGAATCAAAT
CCAAGCTTTCTGATCGTTCTCCTGATATTGACAATTATTCTGAGGAAGAGGAAGAGAGTTTCTCATCAGAACAGGAAGGCAGTGATGATC
CATTGCATGGGCAGGACTTGTTCTACGAAGACGAAGATCTCCGGAAAGTGAAGAAGACCCGGAGGAAACTAACCTCAACCTCTGCCATCA
CAAGGCAACCTAACATCAAACAGAAGTTTGTGGCCCTCCTGAAGCGGTTTAAAGTTTCAGATGAGGTGGGCTTTGGGCTGGAGCATGTGT
CCCGCGAGCAGATCCGGGAAGTGGAAGAGGACTTGGATGAATTGTATGACAGTCTGGAGATGTACAACCCCAGCGACAGTGGCCCTGAGA
TGGAGGAGACAGAAAGCATCCTCAGCACGCCAAAGCCCAAGCTCAAGCCTTTCTTTGAGGGGATGTCGCAGTCCAGCTCCCAGACGGAGA
TTGGCAGCCTCAACAGCAAAGGCAGCCTCGGAAAAGACACCACCAGCCCTATGGAATTGGCTGCTCTAGAAAAAATTAAATCTACTTGGA
TTAAAAACCAAGATGACAGCTTGACTGAAACAGACACTCTGGAAATCACTGACCAGGACATGTTTGGAGATGCCAGCACGAGTCTGGTTG
TGCCGGAGAAAGTCAAAACTCCCATGAAGTCCAGTAAAACGGATCTCCAGGGCTCTGCCTCCCCCAGCAAAGTGGAGGGGGTGCACACAC
CCCGGCAGAAGAGGAGCACGCCCCTGAAGGAGCGGCAGCTCTCCAAGCCCCTAAGTGAGAGGACCAACAGTTCCGACAGCGAGCGCTCCC
CAGATCTGGGCCACAGCACGCAGATTCCAAGAAAGGTGGTGTATGACCAGCTCAATCAGATCCTGGTGTCAGATGCAGCCCTCCCAGAAA
ATGTCATTCTGGTGAACACCACTGACTGGCAGGGCCAGTATGTGGCTGAGCTGCTCCAGGACCAGCGGAAGCCTGTGGTGTGCACCTGCT
CCACCGTGGAGGTCCAGGCCGTGCTGTCCGCCCTGCTCACCCGGATCCAGCGCTACTGCAACTGCAACTCTTCCATGCCGAGGCCAGTGA
AGGTGGCTGCTGTGGGAGGCCAGAGCTACCTGAGCTCCATCCTCAGGTTCTTTGTCAAGTCCCTGGCCAACAAGACCTCCGACTGGCTTG
GCTACATGCGCTTCCTCATCATCCCCCTCGGTTCTCACCCTGTGGCCAAATACTTGGGGTCAGTCGACAGTAAATACAGTAGTTCCTTCC
TGGATTCTGGTTGGAGAGATCTGTTCAGTCGCTCGGAGCCACCAGTGTCAGAGCAACTGGACGTGGCAGGGCGGGTGATGCAGTACGTCA
ACGGGGCAGCCACGACACACCAGCTTCCCGTGGCCGAAGCCATGCTGACTTGCCGGCATAAGTTCCCTGATGAAGACTCCTATCAGAAGT
TTATTCCCTTCATTGGCGTGGTGAAGGTGGGTCTGGTTGAAGACTCTCCCTCCACAGCAGGCGATGGGGACGATTCTCCTGTGGTCAGCC
TTACTGTGCCCTCCACATCACCACCCTCCAGCTCGGGCCTGAGCCGAGACGCCACGGCCACCCCTCCCTCCTCCCCATCTATGAGCAGCG
CCCTGGCCATCGTGGGGAGCCCTAATAGCCCATATGGGGACGTGATTGGCCTCCAGGTGGACTACTGGCTGGGCCACCCCGGGGAGCGGA
GGAGGGAAGGCGACAAGAGGGACGCCAGCTCGAAGAACACCCTCAAGAGTGTCTTCCGCTCAGTGCAGGTGTCCCGCCTGCCCCATAGTG
GGGAGGCCCAGCTTTCTGGCACCATGGCCATGACTGTGGTCACCAAAGAAAAGAACAAGAAAGTTCCCACCATCTTCCTGAGCAAGAAAC
CCCGAGAAAAGGAGGTGGATTCTAAGAGCCAGGTCATTGAAGGCATCAGCCGCCTCATCTGCTCAGCCAAGCAGCAGCAGACTATGCTGA
GAGTGTCCATCGATGGGGTCGAGTGGAGTGACATCAAGTTCTTCCAGCTGGCAGCCCAGTGGCCCACCCATGTCAAGCACTTTCCAGTGG
GACTCTTCAGTGGCAGCAAGGCCACCTGAGGCCCTGTCTCCCAGCCACTTTCCCTCCTGGCACTGCCACCAGCCTCACCGCCTGCGGGCA
GGGGGAGGCCAGCAGGCCCGGGCCCAGCACCCCTTCCCTGGCACCAGGGTCTGCCTCTCACTCGCCCAGGTCCCGAAGGACACTGCCACA
GGGACGCCTTCCCTCCCCTCCCCTCCAGCCCACCCCTGCACAGCCCCTCCTCCTTCCCGCTTTTCCCCTTCTCCCTCCTGCTCCAGGCCC
AAGGCGTGTTGGTTTTGCCTTCTGGTGCCCATAGTCCCCTGGACTGAGTCCCCCAGGCCTTCCTTCACCCGACTTCCAAACTCTTCCTTG
TGGTATCAGTTTCCTTCTCGGAAATGAGAAAGCTGGAATCCTGGTCCCCAGCAGGAGAGCCTAGTCCTCCCCCAGCCCCTCCAGCCACCA
GGGTGTCCTCTAGGATGCAGCTGCCAGATCCACTCACTCTGCTGCCTCCAGCAGGACCCAAGGCCACTTTCAACTCTTATGGGGTTCTCC
ACCTGCCCCAGAGCTTCTCAAGGGAGGGTAAGGGGGCACCCTGAGCCCACAGGACCCCTACTTCACAGCTCACAGGGGCAGGAGGCAGCT
CCCCTGCCTCCAGGACCCTGTTGCTATGGTGACACAGCGTTTCTAGGACAGAGGGGCCTCCCAGTCTCCCCCCACCACCCGTGCACGACT
TCCTCACCACCCCCAGGTTCCCTGCAGATGTCGTGTGTGTCCTGAGTGTTTCTTTGGTTCTTTGCACGCCAAGTCTCTTGGTTGTACCAT
GTGACACACCCTGTGCACTGGTCGCTGTCTTCGTGGCTTCCACCCTTGTTAATGATGCTCCTGCCTCTGCCTCCCAGCCCCTCACCCAGC
ACAGCTCTGCCTGGACTTGGAGAGATGGGAGGCAGACCCCCACCACCATACATGCTGTCTGTGGCCCCTCAGACATTCTGTTTCATCTCC
CATTCATCTCCCTCCTCCCACCGTGTCAGTTTTTCTGCCTTTCCCTGCTCTGTTCTTCCCCCTCCTTAGGCCCCAGCCTGGGCCCAGACC
CATCCTCCCAGCCAGGTTTCCCTCCAGCAGGCTCCTTCCCTCCCTGTCACCTCCCTCTCACCAACCCGGGGTCTGAGCCCCTCATTCCTG
ACCGTCCGTGTTCTCAGGAGTGGTTGAGGACACAGGGCCCCAGCCCAGCCCTCTGCACCCCCCAGCCCGGCCATCTGCGCCCCACAGCCC
CTTTGGAGCTTTTCTCTTGTCCTCTCACTCCTTCCCAGAAGTTTTTGCACAGAACTTCATTTTGAAAGTGTTTTTCTCATTCTCCATACC
TCCCCCAAGCTCTCCTCCAGCCCTTCCCAGGGCTCAGCCCTGCTGTCCTGAGCGTCTCCTGGGCCAGAGAGAGGAGATGGGGGTGGGAGG

>In-frame_ENST00000279270_ENST00000320580_TCGA-A6-A56B-01A_SCYL1_chr11_65300276_+_PACS1_chr11_65977833_length(amino acids)=1225AA_start in transcript=41_stop in transcript=3718
MWFFARDPVRDFPFELIPEPPEGGLPGPWALHRGRKKATGSPVSIFVYDVKPGAEEQTQVAKAAFKRFKTLRHPNILAYIDGLETEKCLH
VVTEAVTPLGIYLKARVEAGGLKELEISWGLHQIVKALSFLVNDCSLIHNNVCMAAVFVDRAGEWKLGGLDYMYSAQGNGGGPPRKGIPE
LEQYDPPELADSSGRVVREKWSADMWRLGCLIWEVFNGPLPRAAALRNPGKIPKTLVPHYCELVGANPKVRPNPARFLQNCRAPGGFMSN
RFVETNLFLEEIQIKEPAEKQKFFQELSKSLDAFPEDFCRHKVLPQLLTAFEFGNAGAVVLTPLFKVGKFLSAEEYQQKIIPVVVKMFSS
TDRAMRIRLLQQMEQFIQYLDEPTVNTQIFPHVVHGFLDTNPAIREQTVKGSKRILRSNEIVLPASGLVETELQLTFSLQYPHFLKRDAN
KLQIMLQRRKRYKNRTILGYKTLAVGLINMAEVMQHPNEGALVLGLHSNVKDVSVPVAEIKIYSLSSQPIDHEGIKSKLSDRSPDIDNYS
EEEEESFSSEQEGSDDPLHGQDLFYEDEDLRKVKKTRRKLTSTSAITRQPNIKQKFVALLKRFKVSDEVGFGLEHVSREQIREVEEDLDE
LYDSLEMYNPSDSGPEMEETESILSTPKPKLKPFFEGMSQSSSQTEIGSLNSKGSLGKDTTSPMELAALEKIKSTWIKNQDDSLTETDTL
EITDQDMFGDASTSLVVPEKVKTPMKSSKTDLQGSASPSKVEGVHTPRQKRSTPLKERQLSKPLSERTNSSDSERSPDLGHSTQIPRKVV
YDQLNQILVSDAALPENVILVNTTDWQGQYVAELLQDQRKPVVCTCSTVEVQAVLSALLTRIQRYCNCNSSMPRPVKVAAVGGQSYLSSI
LRFFVKSLANKTSDWLGYMRFLIIPLGSHPVAKYLGSVDSKYSSSFLDSGWRDLFSRSEPPVSEQLDVAGRVMQYVNGAATTHQLPVAEA
MLTCRHKFPDEDSYQKFIPFIGVVKVGLVEDSPSTAGDGDDSPVVSLTVPSTSPPSSSGLSRDATATPPSSPSMSSALAIVGSPNSPYGD
VIGLQVDYWLGHPGERRREGDKRDASSKNTLKSVFRSVQVSRLPHSGEAQLSGTMAMTVVTKEKNKKVPTIFLSKKPREKEVDSKSQVIE

--------------------------------------------------------------
>In-frame_ENST00000524944_ENST00000320580_TCGA-A6-A56B-01A_SCYL1_chr11_65300276_+_PACS1_chr11_65977833_length(transcript)=5178nt_BP=1263nt
AAGGCGCCCGAACCCGCGGCGGCGGTGGGGACGATGTGGTTCTTTGCCCGGGACCCGGTCCGGGACTTTCCGTTCGAGCTCATCCCGGAG
CCCCCAGAGGGCGGCCTGCCCGGGCCCTGGGCCCTGCACCGCGGCCGCAAGAAGGCCACAGGCAGCCCCGTGTCCATCTTCGTCTATGAT
GTGAAGCCTGGCGCGGAAGAGCAGACCCAGGTGGCCAAAGCTGCCTTCAAGCGCTTCAAAACTCTACGGCACCCCAACATCCTGGCTTAC
ATCGATGGACTGGAGACAGAAAAATGCCTCCACGTCGTGACAGAGGCTGTGACCCCGTTGGGAATATACCTCAAGGCGAGAGTGGAGGCT
GGTGGCCTGAAGGAGCTGGAGATCTCCTGGGGGCTACACCAGATCGTGAAAGCCCTCAGCTTCCTGGTCAACGACTGCAGCCTCATCCAC
AACAATGTCTGCATGGCCGCCGTGTTCGTGGACCGAGCTGGCGAGTGGAAGCTTGGGGGCCTGGACTACATGTATTCGGCCCAGGGCAAC
GGTGGGGGACCTCCCCGCAAGGGGATCCCCGAGCTTGAGCAGTATGACCCCCCGGAGTTGGCTGACAGCAGTGGCAGAGTGGTCAGAGAG
AAGTGGTCAGCAGACATGTGGCGCTTGGGCTGCCTCATTTGGGAAGTCTTCAATGGGCCCCTACCTCGGGCAGCAGCCCTACGCAACCCT
GGGAAGATCCCCAAAACGCTGGTGCCCCATTACTGTGAGCTGGTGGGAGCAAACCCCAAGGTGCGTCCCAACCCAGCCCGCTTCCTGCAG
AACTGCCGGGCACCTGGTGGCTTCATGAGCAACCGCTTTGTAGAAACCAACCTCTTCCTGGAGGAGATTCAGATCAAAGAGCCAGCCGAG
AAGCAAAAATTCTTCCAGGAGCTGAGCAAGAGCCTGGACGCATTCCCTGAGGATTTCTGTCGGCACAAGGTGCTGCCCCAGCTGCTGACC
GCCTTCGAGTTCGGCAATGCTGGGGCCGTTGTCCTCACGCCCCTCTTCAAGGTGGGCAAGTTCCTGAGCGCTGAGGAGTATCAGCAGAAG
ATCATCCCTGTGGTGGTCAAGATGTTCTCATCCACTGACCGGGCCATGCGCATCCGCCTCCTGCAGCAGATGGAGCAGTTCATCCAGTAC
CTTGACGAGCCAACAGTCAACACCCAGATCTTCCCCCACGTCGTACATGGCTTCCTGGACACCAACCCTGCCATCCGGGAGCAGACGGTC
AAGGGTTCAAAAAGAATTCTTCGCTCCAACGAGATCGTCCTTCCAGCTAGTGGACTGGTGGAAACAGAGCTCCAATTAACCTTCTCCCTT
CAGTACCCTCATTTCCTTAAGCGAGATGCCAACAAGCTGCAGATCATGCTGCAAAGGAGAAAACGTTACAAGAATCGGACCATCTTGGGC
TATAAGACCTTGGCCGTGGGACTCATCAACATGGCAGAGGTGATGCAGCATCCTAATGAAGGCGCACTGGTGCTTGGCCTACACAGCAAC
GTGAAGGATGTCTCTGTGCCTGTGGCAGAAATAAAGATCTACTCCCTGTCCAGCCAACCCATTGACCATGAAGGAATCAAATCCAAGCTT
TCTGATCGTTCTCCTGATATTGACAATTATTCTGAGGAAGAGGAAGAGAGTTTCTCATCAGAACAGGAAGGCAGTGATGATCCATTGCAT
GGGCAGGACTTGTTCTACGAAGACGAAGATCTCCGGAAAGTGAAGAAGACCCGGAGGAAACTAACCTCAACCTCTGCCATCACAAGGCAA
CCTAACATCAAACAGAAGTTTGTGGCCCTCCTGAAGCGGTTTAAAGTTTCAGATGAGGTGGGCTTTGGGCTGGAGCATGTGTCCCGCGAG
CAGATCCGGGAAGTGGAAGAGGACTTGGATGAATTGTATGACAGTCTGGAGATGTACAACCCCAGCGACAGTGGCCCTGAGATGGAGGAG
ACAGAAAGCATCCTCAGCACGCCAAAGCCCAAGCTCAAGCCTTTCTTTGAGGGGATGTCGCAGTCCAGCTCCCAGACGGAGATTGGCAGC
CTCAACAGCAAAGGCAGCCTCGGAAAAGACACCACCAGCCCTATGGAATTGGCTGCTCTAGAAAAAATTAAATCTACTTGGATTAAAAAC
CAAGATGACAGCTTGACTGAAACAGACACTCTGGAAATCACTGACCAGGACATGTTTGGAGATGCCAGCACGAGTCTGGTTGTGCCGGAG
AAAGTCAAAACTCCCATGAAGTCCAGTAAAACGGATCTCCAGGGCTCTGCCTCCCCCAGCAAAGTGGAGGGGGTGCACACACCCCGGCAG
AAGAGGAGCACGCCCCTGAAGGAGCGGCAGCTCTCCAAGCCCCTAAGTGAGAGGACCAACAGTTCCGACAGCGAGCGCTCCCCAGATCTG
GGCCACAGCACGCAGATTCCAAGAAAGGTGGTGTATGACCAGCTCAATCAGATCCTGGTGTCAGATGCAGCCCTCCCAGAAAATGTCATT
CTGGTGAACACCACTGACTGGCAGGGCCAGTATGTGGCTGAGCTGCTCCAGGACCAGCGGAAGCCTGTGGTGTGCACCTGCTCCACCGTG
GAGGTCCAGGCCGTGCTGTCCGCCCTGCTCACCCGGATCCAGCGCTACTGCAACTGCAACTCTTCCATGCCGAGGCCAGTGAAGGTGGCT
GCTGTGGGAGGCCAGAGCTACCTGAGCTCCATCCTCAGGTTCTTTGTCAAGTCCCTGGCCAACAAGACCTCCGACTGGCTTGGCTACATG
CGCTTCCTCATCATCCCCCTCGGTTCTCACCCTGTGGCCAAATACTTGGGGTCAGTCGACAGTAAATACAGTAGTTCCTTCCTGGATTCT
GGTTGGAGAGATCTGTTCAGTCGCTCGGAGCCACCAGTGTCAGAGCAACTGGACGTGGCAGGGCGGGTGATGCAGTACGTCAACGGGGCA
GCCACGACACACCAGCTTCCCGTGGCCGAAGCCATGCTGACTTGCCGGCATAAGTTCCCTGATGAAGACTCCTATCAGAAGTTTATTCCC
TTCATTGGCGTGGTGAAGGTGGGTCTGGTTGAAGACTCTCCCTCCACAGCAGGCGATGGGGACGATTCTCCTGTGGTCAGCCTTACTGTG
CCCTCCACATCACCACCCTCCAGCTCGGGCCTGAGCCGAGACGCCACGGCCACCCCTCCCTCCTCCCCATCTATGAGCAGCGCCCTGGCC
ATCGTGGGGAGCCCTAATAGCCCATATGGGGACGTGATTGGCCTCCAGGTGGACTACTGGCTGGGCCACCCCGGGGAGCGGAGGAGGGAA
GGCGACAAGAGGGACGCCAGCTCGAAGAACACCCTCAAGAGTGTCTTCCGCTCAGTGCAGGTGTCCCGCCTGCCCCATAGTGGGGAGGCC
CAGCTTTCTGGCACCATGGCCATGACTGTGGTCACCAAAGAAAAGAACAAGAAAGTTCCCACCATCTTCCTGAGCAAGAAACCCCGAGAA
AAGGAGGTGGATTCTAAGAGCCAGGTCATTGAAGGCATCAGCCGCCTCATCTGCTCAGCCAAGCAGCAGCAGACTATGCTGAGAGTGTCC
ATCGATGGGGTCGAGTGGAGTGACATCAAGTTCTTCCAGCTGGCAGCCCAGTGGCCCACCCATGTCAAGCACTTTCCAGTGGGACTCTTC
AGTGGCAGCAAGGCCACCTGAGGCCCTGTCTCCCAGCCACTTTCCCTCCTGGCACTGCCACCAGCCTCACCGCCTGCGGGCAGGGGGAGG
CCAGCAGGCCCGGGCCCAGCACCCCTTCCCTGGCACCAGGGTCTGCCTCTCACTCGCCCAGGTCCCGAAGGACACTGCCACAGGGACGCC
TTCCCTCCCCTCCCCTCCAGCCCACCCCTGCACAGCCCCTCCTCCTTCCCGCTTTTCCCCTTCTCCCTCCTGCTCCAGGCCCAAGGCGTG
TTGGTTTTGCCTTCTGGTGCCCATAGTCCCCTGGACTGAGTCCCCCAGGCCTTCCTTCACCCGACTTCCAAACTCTTCCTTGTGGTATCA
GTTTCCTTCTCGGAAATGAGAAAGCTGGAATCCTGGTCCCCAGCAGGAGAGCCTAGTCCTCCCCCAGCCCCTCCAGCCACCAGGGTGTCC
TCTAGGATGCAGCTGCCAGATCCACTCACTCTGCTGCCTCCAGCAGGACCCAAGGCCACTTTCAACTCTTATGGGGTTCTCCACCTGCCC
CAGAGCTTCTCAAGGGAGGGTAAGGGGGCACCCTGAGCCCACAGGACCCCTACTTCACAGCTCACAGGGGCAGGAGGCAGCTCCCCTGCC
TCCAGGACCCTGTTGCTATGGTGACACAGCGTTTCTAGGACAGAGGGGCCTCCCAGTCTCCCCCCACCACCCGTGCACGACTTCCTCACC
ACCCCCAGGTTCCCTGCAGATGTCGTGTGTGTCCTGAGTGTTTCTTTGGTTCTTTGCACGCCAAGTCTCTTGGTTGTACCATGTGACACA
CCCTGTGCACTGGTCGCTGTCTTCGTGGCTTCCACCCTTGTTAATGATGCTCCTGCCTCTGCCTCCCAGCCCCTCACCCAGCACAGCTCT
GCCTGGACTTGGAGAGATGGGAGGCAGACCCCCACCACCATACATGCTGTCTGTGGCCCCTCAGACATTCTGTTTCATCTCCCATTCATC
TCCCTCCTCCCACCGTGTCAGTTTTTCTGCCTTTCCCTGCTCTGTTCTTCCCCCTCCTTAGGCCCCAGCCTGGGCCCAGACCCATCCTCC
CAGCCAGGTTTCCCTCCAGCAGGCTCCTTCCCTCCCTGTCACCTCCCTCTCACCAACCCGGGGTCTGAGCCCCTCATTCCTGACCGTCCG
TGTTCTCAGGAGTGGTTGAGGACACAGGGCCCCAGCCCAGCCCTCTGCACCCCCCAGCCCGGCCATCTGCGCCCCACAGCCCCTTTGGAG
CTTTTCTCTTGTCCTCTCACTCCTTCCCAGAAGTTTTTGCACAGAACTTCATTTTGAAAGTGTTTTTCTCATTCTCCATACCTCCCCCAA
GCTCTCCTCCAGCCCTTCCCAGGGCTCAGCCCTGCTGTCCTGAGCGTCTCCTGGGCCAGAGAGAGGAGATGGGGGTGGGAGGGACTGAGT

>In-frame_ENST00000524944_ENST00000320580_TCGA-A6-A56B-01A_SCYL1_chr11_65300276_+_PACS1_chr11_65977833_length(amino acids)=1225AA_start in transcript=33_stop in transcript=3710
MWFFARDPVRDFPFELIPEPPEGGLPGPWALHRGRKKATGSPVSIFVYDVKPGAEEQTQVAKAAFKRFKTLRHPNILAYIDGLETEKCLH
VVTEAVTPLGIYLKARVEAGGLKELEISWGLHQIVKALSFLVNDCSLIHNNVCMAAVFVDRAGEWKLGGLDYMYSAQGNGGGPPRKGIPE
LEQYDPPELADSSGRVVREKWSADMWRLGCLIWEVFNGPLPRAAALRNPGKIPKTLVPHYCELVGANPKVRPNPARFLQNCRAPGGFMSN
RFVETNLFLEEIQIKEPAEKQKFFQELSKSLDAFPEDFCRHKVLPQLLTAFEFGNAGAVVLTPLFKVGKFLSAEEYQQKIIPVVVKMFSS
TDRAMRIRLLQQMEQFIQYLDEPTVNTQIFPHVVHGFLDTNPAIREQTVKGSKRILRSNEIVLPASGLVETELQLTFSLQYPHFLKRDAN
KLQIMLQRRKRYKNRTILGYKTLAVGLINMAEVMQHPNEGALVLGLHSNVKDVSVPVAEIKIYSLSSQPIDHEGIKSKLSDRSPDIDNYS
EEEEESFSSEQEGSDDPLHGQDLFYEDEDLRKVKKTRRKLTSTSAITRQPNIKQKFVALLKRFKVSDEVGFGLEHVSREQIREVEEDLDE
LYDSLEMYNPSDSGPEMEETESILSTPKPKLKPFFEGMSQSSSQTEIGSLNSKGSLGKDTTSPMELAALEKIKSTWIKNQDDSLTETDTL
EITDQDMFGDASTSLVVPEKVKTPMKSSKTDLQGSASPSKVEGVHTPRQKRSTPLKERQLSKPLSERTNSSDSERSPDLGHSTQIPRKVV
YDQLNQILVSDAALPENVILVNTTDWQGQYVAELLQDQRKPVVCTCSTVEVQAVLSALLTRIQRYCNCNSSMPRPVKVAAVGGQSYLSSI
LRFFVKSLANKTSDWLGYMRFLIIPLGSHPVAKYLGSVDSKYSSSFLDSGWRDLFSRSEPPVSEQLDVAGRVMQYVNGAATTHQLPVAEA
MLTCRHKFPDEDSYQKFIPFIGVVKVGLVEDSPSTAGDGDDSPVVSLTVPSTSPPSSSGLSRDATATPPSSPSMSSALAIVGSPNSPYGD
VIGLQVDYWLGHPGERRREGDKRDASSKNTLKSVFRSVQVSRLPHSGEAQLSGTMAMTVVTKEKNKKVPTIFLSKKPREKEVDSKSQVIE

--------------------------------------------------------------
>In-frame_ENST00000527009_ENST00000320580_TCGA-A6-A56B-01A_SCYL1_chr11_65300276_+_PACS1_chr11_65977833_length(transcript)=5195nt_BP=1280nt
GGCGGAGGGACCGAGGGACCGACAGGCGGACAGGGCCGGGGTCACGTGGGCCCGGCGAAGTGTCCCTAAGGCTGACCTGGGGAGAGACCT
GGCTGCGGGCCCTTGTCTTCCGGCCACACAACAGCTCTGGGACCATCTCAGGCCCCGCTGCCCTCCCCTAGGCCACAGGCAGCCCCGTGT
CCATCTTCGTCTATGATGTGAAGCCTGGCGCGGAAGAGCAGACCCAGGTGGCCAAAGCTGCCTTCAAGCGCTTCAAAACTCTACGGCACC
CCAACATCCTGGCTTACATCGATGGACTGGAGACAGAAAAATGCCTCCACGTCGTGACAGAGGCTGTGACCCCGTTGGGAATATACCTCA
AGGCGAGAGTGGAGGCTGGTGGCCTGAAGGAGCTGGAGATCTCCTGGGGGCTACACCAGATCGTGAAAGCCCTCAGCTTCCTGGTCAACG
ACTGCAGCCTCATCCACAACAATGTCTGCATGGCCGCCGTGTTCGTGGACCGAGCTGGCGAGTGGAAGCTTGGGGGCCTGGACTACATGT
ATTCGGCCCAGGGCAACGGTGGGGGACCTCCCCGCAAGGGGATCCCCGAGCTTGAGCAGTATGACCCCCCGGAGTTGGCTGACAGCAGTG
GCAGAGTGGTCAGAGAGAAGTGGTCAGCAGACATGTGGCGCTTGGGCTGCCTCATTTGGGAAGTCTTCAATGGGCCCCTACCTCGGGCAG
CAGCCCTACGCAACCCTGGGAAGATCCCCAAAACGCTGGTGCCCCATTACTGTGAGCTGGTGGGAGCAAACCCCAAGGTGCGTCCCAACC
CAGCCCGCTTCCTGCAGAACTGCCGGGCACCTGGTGGCTTCATGAGCAACCGCTTTGTAGAAACCAACCTCTTCCTGGAGGAGATTCAGA
TCAAAGAGCCAGCCGAGAAGCAAAAATTCTTCCAGGAGCTGAGCAAGAGCCTGGACGCATTCCCTGAGGATTTCTGTCGGCACAAGGTGC
TGCCCCAGCTGCTGACCGCCTTCGAGTTCGGCAATGCTGGGGCCGTTGTCCTCACGCCCCTCTTCAAGGTGGGCAAGTTCCTGAGCGCTG
AGGAGTATCAGCAGAAGATCATCCCTGTGGTGGTCAAGATGTTCTCATCCACTGACCGGGCCATGCGCATCCGCCTCCTGCAGCAGATGG
AGCAGTTCATCCAGTACCTTGACGAGCCAACAGTCAACACCCAGATCTTCCCCCACGTCGTACATGGCTTCCTGGACACCAACCCTGCCA
TCCGGGAGCAGACGGTCAAGGGTTCAAAAAGAATTCTTCGCTCCAACGAGATCGTCCTTCCAGCTAGTGGACTGGTGGAAACAGAGCTCC
AATTAACCTTCTCCCTTCAGTACCCTCATTTCCTTAAGCGAGATGCCAACAAGCTGCAGATCATGCTGCAAAGGAGAAAACGTTACAAGA
ATCGGACCATCTTGGGCTATAAGACCTTGGCCGTGGGACTCATCAACATGGCAGAGGTGATGCAGCATCCTAATGAAGGCGCACTGGTGC
TTGGCCTACACAGCAACGTGAAGGATGTCTCTGTGCCTGTGGCAGAAATAAAGATCTACTCCCTGTCCAGCCAACCCATTGACCATGAAG
GAATCAAATCCAAGCTTTCTGATCGTTCTCCTGATATTGACAATTATTCTGAGGAAGAGGAAGAGAGTTTCTCATCAGAACAGGAAGGCA
GTGATGATCCATTGCATGGGCAGGACTTGTTCTACGAAGACGAAGATCTCCGGAAAGTGAAGAAGACCCGGAGGAAACTAACCTCAACCT
CTGCCATCACAAGGCAACCTAACATCAAACAGAAGTTTGTGGCCCTCCTGAAGCGGTTTAAAGTTTCAGATGAGGTGGGCTTTGGGCTGG
AGCATGTGTCCCGCGAGCAGATCCGGGAAGTGGAAGAGGACTTGGATGAATTGTATGACAGTCTGGAGATGTACAACCCCAGCGACAGTG
GCCCTGAGATGGAGGAGACAGAAAGCATCCTCAGCACGCCAAAGCCCAAGCTCAAGCCTTTCTTTGAGGGGATGTCGCAGTCCAGCTCCC
AGACGGAGATTGGCAGCCTCAACAGCAAAGGCAGCCTCGGAAAAGACACCACCAGCCCTATGGAATTGGCTGCTCTAGAAAAAATTAAAT
CTACTTGGATTAAAAACCAAGATGACAGCTTGACTGAAACAGACACTCTGGAAATCACTGACCAGGACATGTTTGGAGATGCCAGCACGA
GTCTGGTTGTGCCGGAGAAAGTCAAAACTCCCATGAAGTCCAGTAAAACGGATCTCCAGGGCTCTGCCTCCCCCAGCAAAGTGGAGGGGG
TGCACACACCCCGGCAGAAGAGGAGCACGCCCCTGAAGGAGCGGCAGCTCTCCAAGCCCCTAAGTGAGAGGACCAACAGTTCCGACAGCG
AGCGCTCCCCAGATCTGGGCCACAGCACGCAGATTCCAAGAAAGGTGGTGTATGACCAGCTCAATCAGATCCTGGTGTCAGATGCAGCCC
TCCCAGAAAATGTCATTCTGGTGAACACCACTGACTGGCAGGGCCAGTATGTGGCTGAGCTGCTCCAGGACCAGCGGAAGCCTGTGGTGT
GCACCTGCTCCACCGTGGAGGTCCAGGCCGTGCTGTCCGCCCTGCTCACCCGGATCCAGCGCTACTGCAACTGCAACTCTTCCATGCCGA
GGCCAGTGAAGGTGGCTGCTGTGGGAGGCCAGAGCTACCTGAGCTCCATCCTCAGGTTCTTTGTCAAGTCCCTGGCCAACAAGACCTCCG
ACTGGCTTGGCTACATGCGCTTCCTCATCATCCCCCTCGGTTCTCACCCTGTGGCCAAATACTTGGGGTCAGTCGACAGTAAATACAGTA
GTTCCTTCCTGGATTCTGGTTGGAGAGATCTGTTCAGTCGCTCGGAGCCACCAGTGTCAGAGCAACTGGACGTGGCAGGGCGGGTGATGC
AGTACGTCAACGGGGCAGCCACGACACACCAGCTTCCCGTGGCCGAAGCCATGCTGACTTGCCGGCATAAGTTCCCTGATGAAGACTCCT
ATCAGAAGTTTATTCCCTTCATTGGCGTGGTGAAGGTGGGTCTGGTTGAAGACTCTCCCTCCACAGCAGGCGATGGGGACGATTCTCCTG
TGGTCAGCCTTACTGTGCCCTCCACATCACCACCCTCCAGCTCGGGCCTGAGCCGAGACGCCACGGCCACCCCTCCCTCCTCCCCATCTA
TGAGCAGCGCCCTGGCCATCGTGGGGAGCCCTAATAGCCCATATGGGGACGTGATTGGCCTCCAGGTGGACTACTGGCTGGGCCACCCCG
GGGAGCGGAGGAGGGAAGGCGACAAGAGGGACGCCAGCTCGAAGAACACCCTCAAGAGTGTCTTCCGCTCAGTGCAGGTGTCCCGCCTGC
CCCATAGTGGGGAGGCCCAGCTTTCTGGCACCATGGCCATGACTGTGGTCACCAAAGAAAAGAACAAGAAAGTTCCCACCATCTTCCTGA
GCAAGAAACCCCGAGAAAAGGAGGTGGATTCTAAGAGCCAGGTCATTGAAGGCATCAGCCGCCTCATCTGCTCAGCCAAGCAGCAGCAGA
CTATGCTGAGAGTGTCCATCGATGGGGTCGAGTGGAGTGACATCAAGTTCTTCCAGCTGGCAGCCCAGTGGCCCACCCATGTCAAGCACT
TTCCAGTGGGACTCTTCAGTGGCAGCAAGGCCACCTGAGGCCCTGTCTCCCAGCCACTTTCCCTCCTGGCACTGCCACCAGCCTCACCGC
CTGCGGGCAGGGGGAGGCCAGCAGGCCCGGGCCCAGCACCCCTTCCCTGGCACCAGGGTCTGCCTCTCACTCGCCCAGGTCCCGAAGGAC
ACTGCCACAGGGACGCCTTCCCTCCCCTCCCCTCCAGCCCACCCCTGCACAGCCCCTCCTCCTTCCCGCTTTTCCCCTTCTCCCTCCTGC
TCCAGGCCCAAGGCGTGTTGGTTTTGCCTTCTGGTGCCCATAGTCCCCTGGACTGAGTCCCCCAGGCCTTCCTTCACCCGACTTCCAAAC
TCTTCCTTGTGGTATCAGTTTCCTTCTCGGAAATGAGAAAGCTGGAATCCTGGTCCCCAGCAGGAGAGCCTAGTCCTCCCCCAGCCCCTC
CAGCCACCAGGGTGTCCTCTAGGATGCAGCTGCCAGATCCACTCACTCTGCTGCCTCCAGCAGGACCCAAGGCCACTTTCAACTCTTATG
GGGTTCTCCACCTGCCCCAGAGCTTCTCAAGGGAGGGTAAGGGGGCACCCTGAGCCCACAGGACCCCTACTTCACAGCTCACAGGGGCAG
GAGGCAGCTCCCCTGCCTCCAGGACCCTGTTGCTATGGTGACACAGCGTTTCTAGGACAGAGGGGCCTCCCAGTCTCCCCCCACCACCCG
TGCACGACTTCCTCACCACCCCCAGGTTCCCTGCAGATGTCGTGTGTGTCCTGAGTGTTTCTTTGGTTCTTTGCACGCCAAGTCTCTTGG
TTGTACCATGTGACACACCCTGTGCACTGGTCGCTGTCTTCGTGGCTTCCACCCTTGTTAATGATGCTCCTGCCTCTGCCTCCCAGCCCC
TCACCCAGCACAGCTCTGCCTGGACTTGGAGAGATGGGAGGCAGACCCCCACCACCATACATGCTGTCTGTGGCCCCTCAGACATTCTGT
TTCATCTCCCATTCATCTCCCTCCTCCCACCGTGTCAGTTTTTCTGCCTTTCCCTGCTCTGTTCTTCCCCCTCCTTAGGCCCCAGCCTGG
GCCCAGACCCATCCTCCCAGCCAGGTTTCCCTCCAGCAGGCTCCTTCCCTCCCTGTCACCTCCCTCTCACCAACCCGGGGTCTGAGCCCC
TCATTCCTGACCGTCCGTGTTCTCAGGAGTGGTTGAGGACACAGGGCCCCAGCCCAGCCCTCTGCACCCCCCAGCCCGGCCATCTGCGCC
CCACAGCCCCTTTGGAGCTTTTCTCTTGTCCTCTCACTCCTTCCCAGAAGTTTTTGCACAGAACTTCATTTTGAAAGTGTTTTTCTCATT
CTCCATACCTCCCCCAAGCTCTCCTCCAGCCCTTCCCAGGGCTCAGCCCTGCTGTCCTGAGCGTCTCCTGGGCCAGAGAGAGGAGATGGG

>In-frame_ENST00000527009_ENST00000320580_TCGA-A6-A56B-01A_SCYL1_chr11_65300276_+_PACS1_chr11_65977833_length(amino acids)=1149AA_start in transcript=278_stop in transcript=3727
MAYIDGLETEKCLHVVTEAVTPLGIYLKARVEAGGLKELEISWGLHQIVKALSFLVNDCSLIHNNVCMAAVFVDRAGEWKLGGLDYMYSA
QGNGGGPPRKGIPELEQYDPPELADSSGRVVREKWSADMWRLGCLIWEVFNGPLPRAAALRNPGKIPKTLVPHYCELVGANPKVRPNPAR
FLQNCRAPGGFMSNRFVETNLFLEEIQIKEPAEKQKFFQELSKSLDAFPEDFCRHKVLPQLLTAFEFGNAGAVVLTPLFKVGKFLSAEEY
QQKIIPVVVKMFSSTDRAMRIRLLQQMEQFIQYLDEPTVNTQIFPHVVHGFLDTNPAIREQTVKGSKRILRSNEIVLPASGLVETELQLT
FSLQYPHFLKRDANKLQIMLQRRKRYKNRTILGYKTLAVGLINMAEVMQHPNEGALVLGLHSNVKDVSVPVAEIKIYSLSSQPIDHEGIK
SKLSDRSPDIDNYSEEEEESFSSEQEGSDDPLHGQDLFYEDEDLRKVKKTRRKLTSTSAITRQPNIKQKFVALLKRFKVSDEVGFGLEHV
SREQIREVEEDLDELYDSLEMYNPSDSGPEMEETESILSTPKPKLKPFFEGMSQSSSQTEIGSLNSKGSLGKDTTSPMELAALEKIKSTW
IKNQDDSLTETDTLEITDQDMFGDASTSLVVPEKVKTPMKSSKTDLQGSASPSKVEGVHTPRQKRSTPLKERQLSKPLSERTNSSDSERS
PDLGHSTQIPRKVVYDQLNQILVSDAALPENVILVNTTDWQGQYVAELLQDQRKPVVCTCSTVEVQAVLSALLTRIQRYCNCNSSMPRPV
KVAAVGGQSYLSSILRFFVKSLANKTSDWLGYMRFLIIPLGSHPVAKYLGSVDSKYSSSFLDSGWRDLFSRSEPPVSEQLDVAGRVMQYV
NGAATTHQLPVAEAMLTCRHKFPDEDSYQKFIPFIGVVKVGLVEDSPSTAGDGDDSPVVSLTVPSTSPPSSSGLSRDATATPPSSPSMSS
ALAIVGSPNSPYGDVIGLQVDYWLGHPGERRREGDKRDASSKNTLKSVFRSVQVSRLPHSGEAQLSGTMAMTVVTKEKNKKVPTIFLSKK

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Fusion Gene PPI Analysis for SCYL1-PACS1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneSCYL1chr11:65300276chr11:65977833ENST00000270176+918793_808410.0809.0COPB1
HgeneSCYL1chr11:65300276chr11:65977833ENST00000279270+917793_808410.0782.0COPB1
HgeneSCYL1chr11:65300276chr11:65977833ENST00000420247+918793_808410.0792.0COPB1
HgeneSCYL1chr11:65300276chr11:65977833ENST00000533862+918793_808410.0788.0COPB1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SCYL1-PACS1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SCYL1-PACS1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneSCYL1C4225236SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 212GENOMICS_ENGLAND;ORPHANET
TgenePACS1C3714756Intellectual Disability2GENOMICS_ENGLAND
TgenePACS1C0005586Bipolar Disorder1CTD_human
TgenePACS1C0005587Depression, Bipolar1CTD_human
TgenePACS1C0013146Drug abuse1CTD_human
TgenePACS1C0013170Drug habituation1CTD_human
TgenePACS1C0013222Drug Use Disorders1CTD_human
TgenePACS1C0024713Manic Disorder1CTD_human
TgenePACS1C0028754Obesity1CTD_human
TgenePACS1C0029231Organic Mental Disorders, Substance-Induced1CTD_human
TgenePACS1C0038580Substance Dependence1CTD_human
TgenePACS1C0038586Substance Use Disorders1CTD_human
TgenePACS1C0236969Substance-Related Disorders1CTD_human
TgenePACS1C0338831Manic1CTD_human
TgenePACS1C0740858Substance abuse problem1CTD_human
TgenePACS1C1510472Drug Dependence1CTD_human
TgenePACS1C3554343MENTAL RETARDATION, AUTOSOMAL DOMINANT 171GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgenePACS1C4316881Prescription Drug Abuse1CTD_human