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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:SEL1L3-ATG12 (FusionGDB2 ID:79717) |
Fusion Gene Summary for SEL1L3-ATG12 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SEL1L3-ATG12 | Fusion gene ID: 79717 | Hgene | Tgene | Gene symbol | SEL1L3 | ATG12 | Gene ID | 23231 | 9140 |
| Gene name | SEL1L family member 3 | autophagy related 12 | |
| Synonyms | Sel-1L3 | APG12|APG12L|FBR93|HAPG12 | |
| Cytomap | 4p15.2 | 5q22.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | protein sel-1 homolog 3sel-1 suppressor of lin-12-like 3suppressor of lin-12-like protein 3 | ubiquitin-like protein ATG12APG12 autophagy 12-likeATG12 autophagy related 12 homologApg12 (autophagy, yeast) homolog | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | O94817 | |
| Ensembl transtripts involved in fusion gene | ENST00000399878, ENST00000264868, ENST00000502949, ENST00000513364, | ENST00000274459, ENST00000509910, ENST00000500945, ENST00000509598, | |
| Fusion gene scores | * DoF score | 11 X 12 X 7=924 | 5 X 4 X 3=60 |
| # samples | 12 | 5 | |
| ** MAII score | log2(12/924*10)=-2.94485844580754 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/60*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SEL1L3 [Title/Abstract] AND ATG12 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | SEL1L3(25766947)-ATG12(115168361), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across SEL1L3 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene breakpoints across ATG12 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | Non-Cancer | 231N | SEL1L3 | chr4 | 25766947 | - | ATG12 | chr5 | 115168361 | - |
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Fusion Gene ORF analysis for SEL1L3-ATG12 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000399878 | ENST00000274459 | SEL1L3 | chr4 | 25766947 | - | ATG12 | chr5 | 115168361 | - |
| In-frame | ENST00000399878 | ENST00000509910 | SEL1L3 | chr4 | 25766947 | - | ATG12 | chr5 | 115168361 | - |
| Frame-shift | ENST00000399878 | ENST00000500945 | SEL1L3 | chr4 | 25766947 | - | ATG12 | chr5 | 115168361 | - |
| 5CDS-5UTR | ENST00000399878 | ENST00000509598 | SEL1L3 | chr4 | 25766947 | - | ATG12 | chr5 | 115168361 | - |
| In-frame | ENST00000264868 | ENST00000274459 | SEL1L3 | chr4 | 25766947 | - | ATG12 | chr5 | 115168361 | - |
| In-frame | ENST00000264868 | ENST00000509910 | SEL1L3 | chr4 | 25766947 | - | ATG12 | chr5 | 115168361 | - |
| Frame-shift | ENST00000264868 | ENST00000500945 | SEL1L3 | chr4 | 25766947 | - | ATG12 | chr5 | 115168361 | - |
| 5CDS-5UTR | ENST00000264868 | ENST00000509598 | SEL1L3 | chr4 | 25766947 | - | ATG12 | chr5 | 115168361 | - |
| Frame-shift | ENST00000502949 | ENST00000274459 | SEL1L3 | chr4 | 25766947 | - | ATG12 | chr5 | 115168361 | - |
| Frame-shift | ENST00000502949 | ENST00000509910 | SEL1L3 | chr4 | 25766947 | - | ATG12 | chr5 | 115168361 | - |
| In-frame | ENST00000502949 | ENST00000500945 | SEL1L3 | chr4 | 25766947 | - | ATG12 | chr5 | 115168361 | - |
| 5CDS-5UTR | ENST00000502949 | ENST00000509598 | SEL1L3 | chr4 | 25766947 | - | ATG12 | chr5 | 115168361 | - |
| intron-3CDS | ENST00000513364 | ENST00000274459 | SEL1L3 | chr4 | 25766947 | - | ATG12 | chr5 | 115168361 | - |
| intron-3CDS | ENST00000513364 | ENST00000509910 | SEL1L3 | chr4 | 25766947 | - | ATG12 | chr5 | 115168361 | - |
| intron-3CDS | ENST00000513364 | ENST00000500945 | SEL1L3 | chr4 | 25766947 | - | ATG12 | chr5 | 115168361 | - |
| intron-5UTR | ENST00000513364 | ENST00000509598 | SEL1L3 | chr4 | 25766947 | - | ATG12 | chr5 | 115168361 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000399878 | SEL1L3 | chr4 | 25766947 | - | ENST00000274459 | ATG12 | chr5 | 115168361 | - | 6809 | 3078 | 78 | 3200 | 1040 |
| ENST00000399878 | SEL1L3 | chr4 | 25766947 | - | ENST00000509910 | ATG12 | chr5 | 115168361 | - | 6805 | 3078 | 78 | 3200 | 1040 |
| ENST00000264868 | SEL1L3 | chr4 | 25766947 | - | ENST00000274459 | ATG12 | chr5 | 115168361 | - | 6664 | 2933 | 20 | 3055 | 1011 |
| ENST00000264868 | SEL1L3 | chr4 | 25766947 | - | ENST00000509910 | ATG12 | chr5 | 115168361 | - | 6660 | 2933 | 20 | 3055 | 1011 |
| ENST00000502949 | SEL1L3 | chr4 | 25766947 | - | ENST00000500945 | ATG12 | chr5 | 115168361 | - | 4151 | 2897 | 17 | 3019 | 1000 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000399878 | ENST00000274459 | SEL1L3 | chr4 | 25766947 | - | ATG12 | chr5 | 115168361 | - | 0.000106375 | 0.99989367 |
| ENST00000399878 | ENST00000509910 | SEL1L3 | chr4 | 25766947 | - | ATG12 | chr5 | 115168361 | - | 0.000107483 | 0.9998925 |
| ENST00000264868 | ENST00000274459 | SEL1L3 | chr4 | 25766947 | - | ATG12 | chr5 | 115168361 | - | 9.70E-05 | 0.99990296 |
| ENST00000264868 | ENST00000509910 | SEL1L3 | chr4 | 25766947 | - | ATG12 | chr5 | 115168361 | - | 9.81E-05 | 0.9999019 |
| ENST00000502949 | ENST00000500945 | SEL1L3 | chr4 | 25766947 | - | ATG12 | chr5 | 115168361 | - | 0.000514713 | 0.99948525 |
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Fusion Genomic Features for SEL1L3-ATG12 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for SEL1L3-ATG12 |
| Go to FGviewer for the breakpoints of chr4:25766947-chr5:115168361 - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | ATG12 |
| FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes. | FUNCTION: Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. {ECO:0000269|PubMed:12207896, ECO:0000269|PubMed:17999726, ECO:0000269|PubMed:19074260, ECO:0000269|PubMed:19164948, ECO:0000269|PubMed:23202584}.; FUNCTION: (Microbial infection) May act as a proviral factor. In association with ATG5, negatively regulates the innate antiviral immune response by impairing the type I IFN production pathway upon vesicular stomatitis virus (VSV) infection (PubMed:17709747). Required for the translation of incoming hepatitis C virus (HCV) RNA and, thereby, for the initiation of HCV replication, but not required once infection is established (PubMed:19666601). {ECO:0000269|PubMed:17709747, ECO:0000269|PubMed:19666601}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SEL1L3 | chr4:25766947 | chr5:115168361 | ENST00000264868 | - | 20 | 24 | 575_609 | 950.0 | 1098.0 | Repeat | Note=Sel1-like 1 |
| Hgene | SEL1L3 | chr4:25766947 | chr5:115168361 | ENST00000264868 | - | 20 | 24 | 611_647 | 950.0 | 1098.0 | Repeat | Note=Sel1-like 2 |
| Hgene | SEL1L3 | chr4:25766947 | chr5:115168361 | ENST00000264868 | - | 20 | 24 | 694_730 | 950.0 | 1098.0 | Repeat | Note=Sel1-like 3 |
| Hgene | SEL1L3 | chr4:25766947 | chr5:115168361 | ENST00000264868 | - | 20 | 24 | 732_767 | 950.0 | 1098.0 | Repeat | Note=Sel1-like 4 |
| Hgene | SEL1L3 | chr4:25766947 | chr5:115168361 | ENST00000264868 | - | 20 | 24 | 768_800 | 950.0 | 1098.0 | Repeat | Note=Sel1-like 5 |
| Hgene | SEL1L3 | chr4:25766947 | chr5:115168361 | ENST00000264868 | - | 20 | 24 | 801_839 | 950.0 | 1098.0 | Repeat | Note=Sel1-like 6 |
| Hgene | SEL1L3 | chr4:25766947 | chr5:115168361 | ENST00000264868 | - | 20 | 24 | 840_877 | 950.0 | 1098.0 | Repeat | Note=Sel1-like 7 |
| Hgene | SEL1L3 | chr4:25766947 | chr5:115168361 | ENST00000399878 | - | 20 | 24 | 575_609 | 985.0 | 1133.0 | Repeat | Note=Sel1-like 1 |
| Hgene | SEL1L3 | chr4:25766947 | chr5:115168361 | ENST00000399878 | - | 20 | 24 | 611_647 | 985.0 | 1133.0 | Repeat | Note=Sel1-like 2 |
| Hgene | SEL1L3 | chr4:25766947 | chr5:115168361 | ENST00000399878 | - | 20 | 24 | 694_730 | 985.0 | 1133.0 | Repeat | Note=Sel1-like 3 |
| Hgene | SEL1L3 | chr4:25766947 | chr5:115168361 | ENST00000399878 | - | 20 | 24 | 732_767 | 985.0 | 1133.0 | Repeat | Note=Sel1-like 4 |
| Hgene | SEL1L3 | chr4:25766947 | chr5:115168361 | ENST00000399878 | - | 20 | 24 | 768_800 | 985.0 | 1133.0 | Repeat | Note=Sel1-like 5 |
| Hgene | SEL1L3 | chr4:25766947 | chr5:115168361 | ENST00000399878 | - | 20 | 24 | 801_839 | 985.0 | 1133.0 | Repeat | Note=Sel1-like 6 |
| Hgene | SEL1L3 | chr4:25766947 | chr5:115168361 | ENST00000399878 | - | 20 | 24 | 840_877 | 985.0 | 1133.0 | Repeat | Note=Sel1-like 7 |
| Hgene | SEL1L3 | chr4:25766947 | chr5:115168361 | ENST00000399878 | - | 20 | 24 | 952_988 | 985.0 | 1133.0 | Repeat | Note=Sel1-like 8 |
| Hgene | SEL1L3 | chr4:25766947 | chr5:115168361 | ENST00000502949 | - | 20 | 24 | 575_609 | 832.0 | 980.0 | Repeat | Note=Sel1-like 1 |
| Hgene | SEL1L3 | chr4:25766947 | chr5:115168361 | ENST00000502949 | - | 20 | 24 | 611_647 | 832.0 | 980.0 | Repeat | Note=Sel1-like 2 |
| Hgene | SEL1L3 | chr4:25766947 | chr5:115168361 | ENST00000502949 | - | 20 | 24 | 694_730 | 832.0 | 980.0 | Repeat | Note=Sel1-like 3 |
| Hgene | SEL1L3 | chr4:25766947 | chr5:115168361 | ENST00000502949 | - | 20 | 24 | 732_767 | 832.0 | 980.0 | Repeat | Note=Sel1-like 4 |
| Hgene | SEL1L3 | chr4:25766947 | chr5:115168361 | ENST00000502949 | - | 20 | 24 | 768_800 | 832.0 | 980.0 | Repeat | Note=Sel1-like 5 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SEL1L3 | chr4:25766947 | chr5:115168361 | ENST00000264868 | - | 20 | 24 | 952_988 | 950.0 | 1098.0 | Repeat | Note=Sel1-like 8 |
| Hgene | SEL1L3 | chr4:25766947 | chr5:115168361 | ENST00000502949 | - | 20 | 24 | 801_839 | 832.0 | 980.0 | Repeat | Note=Sel1-like 6 |
| Hgene | SEL1L3 | chr4:25766947 | chr5:115168361 | ENST00000502949 | - | 20 | 24 | 840_877 | 832.0 | 980.0 | Repeat | Note=Sel1-like 7 |
| Hgene | SEL1L3 | chr4:25766947 | chr5:115168361 | ENST00000502949 | - | 20 | 24 | 952_988 | 832.0 | 980.0 | Repeat | Note=Sel1-like 8 |
| Hgene | SEL1L3 | chr4:25766947 | chr5:115168361 | ENST00000264868 | - | 20 | 24 | 1057_1077 | 950.0 | 1098.0 | Transmembrane | Helical |
| Hgene | SEL1L3 | chr4:25766947 | chr5:115168361 | ENST00000399878 | - | 20 | 24 | 1057_1077 | 985.0 | 1133.0 | Transmembrane | Helical |
| Hgene | SEL1L3 | chr4:25766947 | chr5:115168361 | ENST00000502949 | - | 20 | 24 | 1057_1077 | 832.0 | 980.0 | Transmembrane | Helical |
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Fusion Gene Sequence for SEL1L3-ATG12 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >In-frame_ENST00000399878_ENST00000274459_231N_SEL1L3_chr4_25766947_-_ATG12_chr5_115168361_length(transcript)=6809nt_BP=3078nt CGGCAGGTGGCCCCGCGCGCGGCGGCCGGCCCGGCCGGGGGCGGGCGGGAAGGTGGCGCCTCGGGCGGGGGCCGGTCCCTGCACCAGGTG ACCTGTTCCGGCCCGGATCCGGGCGGCCTCGCCATGCAGCGGCGCGGCGCGGGGCTCGGGTGGCCGCGGCAGCAGCAGCAGCAACCCCCG CCGCTCGCGGTCGGCCCCCGGGCCGCAGCCATGGTCCCGAGTGGCGGCGTCCCCCAGGGCCTCGGCGGCCGCTCTGCCTGCGCGCTGCTC CTGCTCTGCTACCTGAATGTTGTACCATCTTTGGGTAGGCAGACTTCCCTGACGACATCAGTGATACCCAAAGCTGAGCAGAGCGTGGCT TACAAAGACTTTATTTATTTTACTGTCTTTGAAGGAAACGTTCGCAACGTTTCTGAAGTCTCGGTTGAGTATTTATGCTCTCAGCCTTGT GTTGTCAATTTGGAAGCAGTTGTTTCATCTGAGTTCAGAAGTAGCATTCCCGTGTACAAAAAAAGGTGGAAGAATGAGAAACATCTTCAC ACCAGCAGGACACAAATAGTACATGTGAAATTTCCAAGCATTATGGTTTACAGAGATGATTATTTCATCAGACATTCCATCTCTGTATCT GCAGTGATAGTACGCGCCTGGATTACTCACAAATACAGTGGCAGAGACTGGAATGTTAAATGGGAGGAAAACTTGCTCCATGCTGTAGCA AAGAATTATACCCTCCTGCAGACCATCCCGCCTTTTGAACGCCCTTTCAAAGATCATCAAGTGTGCCTTGAGTGGAACATGGGTTATATT TGGAACCTTCGGGCAAACAGGATTCCACAGTGTCCTCTGGAAAATGATGTGGTTGCCCTGCTTGGCTTTCCTTATGCCTCCAGTGGAGAA AACACAGGCATTGTCAAGAAGTTCCCGAGGTTTCGGAACCGAGAGCTGGAGGCCACTCGACGCCAGAGGATGGATTACCCAGTGTTTACT GTTTCATTGTGGCTTTATTTACTCCATTATTGCAAGGCCAACCTCTGTGGGATTCTGTACTTTGTTGACTCTAATGAGATGTACGGCACA CCTTCTGTATTTCTTACGGAAGAGGGCTATTTGCATATTCAGATGCATCTTGTCAAAGGGGAAGACCTTGCTGTAAAAACTAAATTCATC ATACCTTTGAAGGAGTGGTTTCGACTGGATATCTCTTTTAACGGAGGCCAGATAGTAGTAACCACTAGCATTGGACAGGATTTGAAAAGC TACCACAATCAGACCATTAGCTTCCGGGAGGATTTCCATTATAATGACACAGCTGGGTACTTCATTATTGGAGGGAGCAGGTATGTGGCT GGCATTGAAGGGTTTTTTGGACCCCTGAAGTACTATCGCCTTCGCAGTCTGCACCCCGCCCAGATTTTTAATCCCCTCCTTGAGAAGCAA CTTGCTGAACAAATCAAGTTATATTATGAAAGGTGTGCTGAGGTTCAAGAAATAGTATCTGTGTATGCATCTGCAGCAAAGCACGGGGGC GAGAGACAAGAAGCATGCCACCTCCACAACTCCTACCTGGACCTCCAGCGCAGGTATGGGAGACCCTCGATGTGCAGAGCCTTCCCCTGG GAGAAGGAGCTGAAAGACAAACACCCCAGCTTGTTCCAGGCATTGCTGGAGATGGATCTGCTGACCGTGCCAAGGAACCAAAATGAATCT GTATCAGAAATCGGTGGGAAGATATTTGAGAAGGCTGTAAAGAGACTCTCTAGCATTGATGGTCTTCACCAAATTAGCTCTATCGTCCCC TTTCTGACGGATTCCAGCTGCTGTGGATACCATAAAGCATCCTACTACCTTGCAGTCTTTTATGAGACTGGATTAAATGTTCCTCGGGAT CAGCTGCAGGGCATGTTGTATAGTTTGGTTGGAGGCCAGGGGAGTGAGAGGCTGTCTTCAATGAATCTTGGGTATAAACACTACCAGGGT ATTGACAACTACCCCCTGGACTGGGAACTGTCGTATGCCTACTACAGCAACATTGCCACCAAGACACCCCTTGACCAGCACACACTGCAA GGAGATCAGGCATATGTTGAAACAATTAGACTAAAAGATGATGAAATACTCAAGGTACAAACCAAAGAAGATGGAGATGTCTTTATGTGG TTGAAGCATGAAGCTACCCGAGGCAATGCAGCAGCTCAGCAACGATTGGCCCAGATGCTGTTCTGGGGGCAGCAAGGTGTGGCCAAGAAT CCCGAAGCAGCAATTGAGTGGTACGCCAAGGGCGCCCTGGAGACGGAGGATCCTGCGTTAATCTATGACTATGCCATTGTGCTATTCAAG GGTCAAGGAGTAAAAAAGAACAGACGGCTTGCCTTAGAGCTGATGAAGAAAGCAGCTTCCAAGGGATTGCATCAGGCAGTCAATGGCCTG GGATGGTATTACCACAAATTCAAGAAAAATTACGCCAAAGCAGCAAAGTACTGGTTAAAAGCAGAAGAAATGGGGAACCCAGATGCGTCA TACAATCTTGGAGTCCTGCATTTGGATGGCATCTTCCCTGGAGTTCCTGGAAGGAATCAAACTTTAGCTGGTGAATATTTCCATAAGGCT GCGCAAGGTGGACACATGGAAGGGACCTTGTGGTGTTCTCTCTACTATATCACAGGCAACCTGGAGACATTCCCTAGAGATCCTGAGAAA GCTGTTGTATGGGCAAAACATGTAGCTGAGAAAAATGGCTACTTGGGCCATGTCATCCGCAAAGGCCTCAATGCCTACCTGGAAGGTTCA TGGCATGAAGCTTTGCTGTATTATGTTTTAGCAGCAGAAACTGGAATTGAAGTGTCACAGACAAATTTAGCACACATCTGTGAGGAGAGG CCAGACCTGGCCAGGAGATACTTGGGTGTTAACTGTGTTTGGAGATACTATAATTTCTCTGTTTTTCAAATCGATGCTCCTTCCTTTGCA TATTTGAAGATGGGAGACCTTTACTACTATGGCCACCAAAACCAGTCACAAGACCTGGAGTTGTCTGTGCAGATGTACGCCCAAGCCGCC CTGGATGGAGACTCCCAGTTTATTTATGTGAATCAGTCCTTTGCTCCTTCCCCAGACCAAGAAGTTGGAACTCTCTATGAGTGTTTTGGC AGTGATGGTAAACTGGTTTTACATTACTGCAAGTCTCAGGCGTGGGGATGAACCACAAAGAAAATCAACTTGCTACTACATGAAATGGAT TTTCACGGAAGAGACAGCTCTGAAAAGTTTTGATGCTTGTGGCAAGAGACTTAACAGATGTGATCTATTTAGTATGTGTCTACTCTATGT TTATGCATAAGAAAACATCCATAGCATGAATGGACTCAGAAAAATGTGATTTGTATTAATGCACCAGTCATCATAAAAGATGGTCATGAT AGTACACCCATTGCTCCTACTTGTTACTATTATTGCTGCAGATCTGCCTCCAAGGTTGAAAAGGAGACTAAGACTGTATAAACATCTTCA TTGTCAGTTCTCAAAATGACTGAAATTGTTTTCATGGTAAAAGTTAATATACTAAAGGGTTCCTTTTTTTTTAATGTTTACATTTATCTC TATGTTTACCTTTTTAGTCACATTGACCTGCTGGCTGAATACCTCAAATAGTCCAGTAGAGGGCAGTCCACCAGGCAGAAAAGGTTAGGC GTTTTGGTTTCACATCTTTGCTGGGGAATAATAGGGGAAATGGCTGTTTTTGCTAATTTTTAGCTAATATCTAGCCAGGAGAGCAAGCAC ATAGGACAGACTGAAAGACTGTAATTTTACACAATACACATGGCTTAATTATTTTATTGGGATACAGAAAAATATAAATTCTGGACAAAT AAGTCATATACCTGTTTTCAGTCCTAACATTTAAGGATTCTTGAGTCCCAATCACATAACTGTGGTGTTACTCTGTCATTTATATGGTGT CAAAAGCACTTGATGAGTAAACCCAGTAGCATCTTTTTGAGTGTTTCATAATGCATTTTCCAACTTGAAAACAATAATTGAAAAATAGCC TTATTGTATATTTTATGCCATGACTAAAAGTGCCATTTTTACTGATGCTATTAGACTGATAATTTCTTGAAGTGAAATTTAACCTTTTTT TCTCTTTAGTATTATGTTTATAATGCCATATTTTTAGAAAGCATTCCAGATCAGGCATGGTGGCTTACACCTGTAATCCCAGCACTTTGG AAGGCTGAGGTGTGGGGATTGCGTGAAGCCACAAGTTTGAGACCAGCCTGGTTAGCAAGGCAAGATCCCCAACTCTACAAAAAAATAAAA ATTAAAAAAAAATTATTAGGCTGCAGAGGCAAGAGGATCCCCTGAGCCCAGAAGTTCAAGGGTATAGTGAGTCGTGATTGTACCACTGCA TTCCTGCTGAGCAACAGAGTGAGACCCCATCTCAAAAAAGAAAAAAAAAGGCATTCTAGTAAATCGAATGTAATGTGAATGGAATTTCAA AACAGGATCTAAGATGGTATGTAGTAGAATTCAAAGTAATATCATTTTAAAGTTAAATGAGTATGGAAAAGGTCTGTTCTCTAGTTTTGT CCAGTTCAGTTTACTGAAGGAATATATTTAATTATATTCATATATTTAACAAATAAAAATATGTTGAATTTTCGTATTGTTTGCCACTGA GGGTTCAGATGATAGACCTCAAAAAATCGAAAATACTGGTTGAAATTTGTAGCATCCATTTAGTTATTCTTTTTGACCTAAATAACTTAA TAGTTTATTAAATCTAAGGTTAGCTAAATATGTAGCTAACCTTATTTGTTTTCTTTCCTAACAACTCTGAAGAATACATAGGACTTTGCA CTTTTTTTTTTTTTTTTTTTTTTTAAAGAGACAGCGTTTCGGTCTTGTTGCCCAGGCTGGACTGTAATGGCACAATCTTGGCTCATTGCA ACCTCTACCTCCCGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCACCTGCCACCACACCCGCCTAATTT TTTGTTATTTTTAGTGGAGACAGGGTTTTACCATTTTGGCCAGGCTGGTCTCAAACTCCTGACTGACCTCAGGTGATCCACCCGCCTTGG CCTCCCAAAGTGCTGGGATTATAGGTGTGAGCCACCGTGCCGGGCCTGGACTTTGTACTTTTTCAAATCATATTTAATTATTTCTTGATC TTTACTCAAAGAATTATTCTGCGCTAAATTTGCAACATTAAACAATAATTAAGCCTGGATCCGATAAGTTATTGGGTGACTAGAACCTAC AACACAATTTATTTTTAATTTAAACTCTCAAGTCTGATTAAACTTGGGGGAAAAACTGAACATTCAGGTGATATTTTAAATTTTCTTTGT GACTAAATAGATGTCATTAATATCATGCTTCATCTTACTGTGCATAGATGACCCATGGCACACAAAGTATATGTATAATATTGCAATATT GTACTTCCATCTTTAAAAGTATGCCAAAGACTTCATAATGAATTCACCATATTTAAGGAATAAGGCAAATTAATGTTTATCCGAAATCAA AATGAGATTGGATAATTCCTGGAATCTGATTTCTGTAAGTTTCAGTCCTAAAGGGACCTTAAATATCTACTAGAACGAAGTACAGTGTAT TTCTCAGATTACATGACATTAGTCAACCAATTTAGTTGTAACACAAAGTGAGAAAGCCTTAGGTGTTGAAGGAGTGTGAAAATAAAAATC TCTTTTCATGCAGTTTCTGCTTCATTTTCCAAGGATTATAATATGCTGAGTAAACTTTTGGCACTAAGGAAGCCAGCTACAGGCCACGTA ATGAAAACTATTCAGAAAACAGTTCAGCAAATACTACTATTTGAATACAGTTCAAATCGTATTTATATAAATACTCTGCCTACATTATTT AACCCAAACTGGATTATTCACCATTCTTTGAAGATGCCTTGTGTTTTCTGTTATCTACTTCTGCTCGTGCAGTTTACTTACACCTTCACC CTTTCAAATCCTAACTCTTCTTCAAGGCCTGATTCAGATTTTAACTTTTTAAAGGCTATCTGAATCATTCAAGGAGAAGATACCCTTTCT CTCATAAAAACACTTAGAGCAAACTACCACTATTAAATCACTTATTGCATACTGCCTCAGAGCCATGTGTCCAGTTATTCTGGTTTTTAT CTGGTACCCACACACACATAATACTTAGTACATTTCCTTATATGTAAATAATTAGTAATGTAACACATCGAGTGAATGAAATTGTGATTA GCAAAGTATGACAGCTAAAAACAAAGGAAATTTTGTATAGTTTAAGTTTTTGTACAGCAGAAGGTAATGGAAAATATTTGCAACATATGA CAGTGTTTTTAATGTCTTAAGTATATGAAGAATTTGTTTCAATTGGTAAGAAAAGACCAACTGAAAAATAGGCAAAACATACCAAATTTC GATTCACAAAAAGATACAAATGGCCAACAAAACATGAAACACCTTGAACCCCATTGGTTACAAAAAATACAAATAAAAACAATGCTGACT GACAATAAAAATAATGTACATCTTGCTATTAGCAGAGTTGTGGGGAAATCCTGTCATATTTTGGTGAATAGAATATGAGTTGGTATATCA CTTTTAGGGGGCCATTTGGCAATATCAAAAACCTTGAAACGTAAGTATAAACTTCAGTTTGTTCGTATAACCTGTCATTCACATATTGAG >In-frame_ENST00000399878_ENST00000274459_231N_SEL1L3_chr4_25766947_-_ATG12_chr5_115168361_length(amino acids)=1040AA_start in transcript=78_stop in transcript=3200 MHQVTCSGPDPGGLAMQRRGAGLGWPRQQQQQPPPLAVGPRAAAMVPSGGVPQGLGGRSACALLLLCYLNVVPSLGRQTSLTTSVIPKAE QSVAYKDFIYFTVFEGNVRNVSEVSVEYLCSQPCVVNLEAVVSSEFRSSIPVYKKRWKNEKHLHTSRTQIVHVKFPSIMVYRDDYFIRHS ISVSAVIVRAWITHKYSGRDWNVKWEENLLHAVAKNYTLLQTIPPFERPFKDHQVCLEWNMGYIWNLRANRIPQCPLENDVVALLGFPYA SSGENTGIVKKFPRFRNRELEATRRQRMDYPVFTVSLWLYLLHYCKANLCGILYFVDSNEMYGTPSVFLTEEGYLHIQMHLVKGEDLAVK TKFIIPLKEWFRLDISFNGGQIVVTTSIGQDLKSYHNQTISFREDFHYNDTAGYFIIGGSRYVAGIEGFFGPLKYYRLRSLHPAQIFNPL LEKQLAEQIKLYYERCAEVQEIVSVYASAAKHGGERQEACHLHNSYLDLQRRYGRPSMCRAFPWEKELKDKHPSLFQALLEMDLLTVPRN QNESVSEIGGKIFEKAVKRLSSIDGLHQISSIVPFLTDSSCCGYHKASYYLAVFYETGLNVPRDQLQGMLYSLVGGQGSERLSSMNLGYK HYQGIDNYPLDWELSYAYYSNIATKTPLDQHTLQGDQAYVETIRLKDDEILKVQTKEDGDVFMWLKHEATRGNAAAQQRLAQMLFWGQQG VAKNPEAAIEWYAKGALETEDPALIYDYAIVLFKGQGVKKNRRLALELMKKAASKGLHQAVNGLGWYYHKFKKNYAKAAKYWLKAEEMGN PDASYNLGVLHLDGIFPGVPGRNQTLAGEYFHKAAQGGHMEGTLWCSLYYITGNLETFPRDPEKAVVWAKHVAEKNGYLGHVIRKGLNAY LEGSWHEALLYYVLAAETGIEVSQTNLAHICEERPDLARRYLGVNCVWRYYNFSVFQIDAPSFAYLKMGDLYYYGHQNQSQDLELSVQMY -------------------------------------------------------------- >In-frame_ENST00000399878_ENST00000509910_231N_SEL1L3_chr4_25766947_-_ATG12_chr5_115168361_length(transcript)=6805nt_BP=3078nt CGGCAGGTGGCCCCGCGCGCGGCGGCCGGCCCGGCCGGGGGCGGGCGGGAAGGTGGCGCCTCGGGCGGGGGCCGGTCCCTGCACCAGGTG ACCTGTTCCGGCCCGGATCCGGGCGGCCTCGCCATGCAGCGGCGCGGCGCGGGGCTCGGGTGGCCGCGGCAGCAGCAGCAGCAACCCCCG CCGCTCGCGGTCGGCCCCCGGGCCGCAGCCATGGTCCCGAGTGGCGGCGTCCCCCAGGGCCTCGGCGGCCGCTCTGCCTGCGCGCTGCTC CTGCTCTGCTACCTGAATGTTGTACCATCTTTGGGTAGGCAGACTTCCCTGACGACATCAGTGATACCCAAAGCTGAGCAGAGCGTGGCT TACAAAGACTTTATTTATTTTACTGTCTTTGAAGGAAACGTTCGCAACGTTTCTGAAGTCTCGGTTGAGTATTTATGCTCTCAGCCTTGT GTTGTCAATTTGGAAGCAGTTGTTTCATCTGAGTTCAGAAGTAGCATTCCCGTGTACAAAAAAAGGTGGAAGAATGAGAAACATCTTCAC ACCAGCAGGACACAAATAGTACATGTGAAATTTCCAAGCATTATGGTTTACAGAGATGATTATTTCATCAGACATTCCATCTCTGTATCT GCAGTGATAGTACGCGCCTGGATTACTCACAAATACAGTGGCAGAGACTGGAATGTTAAATGGGAGGAAAACTTGCTCCATGCTGTAGCA AAGAATTATACCCTCCTGCAGACCATCCCGCCTTTTGAACGCCCTTTCAAAGATCATCAAGTGTGCCTTGAGTGGAACATGGGTTATATT TGGAACCTTCGGGCAAACAGGATTCCACAGTGTCCTCTGGAAAATGATGTGGTTGCCCTGCTTGGCTTTCCTTATGCCTCCAGTGGAGAA AACACAGGCATTGTCAAGAAGTTCCCGAGGTTTCGGAACCGAGAGCTGGAGGCCACTCGACGCCAGAGGATGGATTACCCAGTGTTTACT GTTTCATTGTGGCTTTATTTACTCCATTATTGCAAGGCCAACCTCTGTGGGATTCTGTACTTTGTTGACTCTAATGAGATGTACGGCACA CCTTCTGTATTTCTTACGGAAGAGGGCTATTTGCATATTCAGATGCATCTTGTCAAAGGGGAAGACCTTGCTGTAAAAACTAAATTCATC ATACCTTTGAAGGAGTGGTTTCGACTGGATATCTCTTTTAACGGAGGCCAGATAGTAGTAACCACTAGCATTGGACAGGATTTGAAAAGC TACCACAATCAGACCATTAGCTTCCGGGAGGATTTCCATTATAATGACACAGCTGGGTACTTCATTATTGGAGGGAGCAGGTATGTGGCT GGCATTGAAGGGTTTTTTGGACCCCTGAAGTACTATCGCCTTCGCAGTCTGCACCCCGCCCAGATTTTTAATCCCCTCCTTGAGAAGCAA CTTGCTGAACAAATCAAGTTATATTATGAAAGGTGTGCTGAGGTTCAAGAAATAGTATCTGTGTATGCATCTGCAGCAAAGCACGGGGGC GAGAGACAAGAAGCATGCCACCTCCACAACTCCTACCTGGACCTCCAGCGCAGGTATGGGAGACCCTCGATGTGCAGAGCCTTCCCCTGG GAGAAGGAGCTGAAAGACAAACACCCCAGCTTGTTCCAGGCATTGCTGGAGATGGATCTGCTGACCGTGCCAAGGAACCAAAATGAATCT GTATCAGAAATCGGTGGGAAGATATTTGAGAAGGCTGTAAAGAGACTCTCTAGCATTGATGGTCTTCACCAAATTAGCTCTATCGTCCCC TTTCTGACGGATTCCAGCTGCTGTGGATACCATAAAGCATCCTACTACCTTGCAGTCTTTTATGAGACTGGATTAAATGTTCCTCGGGAT CAGCTGCAGGGCATGTTGTATAGTTTGGTTGGAGGCCAGGGGAGTGAGAGGCTGTCTTCAATGAATCTTGGGTATAAACACTACCAGGGT ATTGACAACTACCCCCTGGACTGGGAACTGTCGTATGCCTACTACAGCAACATTGCCACCAAGACACCCCTTGACCAGCACACACTGCAA GGAGATCAGGCATATGTTGAAACAATTAGACTAAAAGATGATGAAATACTCAAGGTACAAACCAAAGAAGATGGAGATGTCTTTATGTGG TTGAAGCATGAAGCTACCCGAGGCAATGCAGCAGCTCAGCAACGATTGGCCCAGATGCTGTTCTGGGGGCAGCAAGGTGTGGCCAAGAAT CCCGAAGCAGCAATTGAGTGGTACGCCAAGGGCGCCCTGGAGACGGAGGATCCTGCGTTAATCTATGACTATGCCATTGTGCTATTCAAG GGTCAAGGAGTAAAAAAGAACAGACGGCTTGCCTTAGAGCTGATGAAGAAAGCAGCTTCCAAGGGATTGCATCAGGCAGTCAATGGCCTG GGATGGTATTACCACAAATTCAAGAAAAATTACGCCAAAGCAGCAAAGTACTGGTTAAAAGCAGAAGAAATGGGGAACCCAGATGCGTCA TACAATCTTGGAGTCCTGCATTTGGATGGCATCTTCCCTGGAGTTCCTGGAAGGAATCAAACTTTAGCTGGTGAATATTTCCATAAGGCT GCGCAAGGTGGACACATGGAAGGGACCTTGTGGTGTTCTCTCTACTATATCACAGGCAACCTGGAGACATTCCCTAGAGATCCTGAGAAA GCTGTTGTATGGGCAAAACATGTAGCTGAGAAAAATGGCTACTTGGGCCATGTCATCCGCAAAGGCCTCAATGCCTACCTGGAAGGTTCA TGGCATGAAGCTTTGCTGTATTATGTTTTAGCAGCAGAAACTGGAATTGAAGTGTCACAGACAAATTTAGCACACATCTGTGAGGAGAGG CCAGACCTGGCCAGGAGATACTTGGGTGTTAACTGTGTTTGGAGATACTATAATTTCTCTGTTTTTCAAATCGATGCTCCTTCCTTTGCA TATTTGAAGATGGGAGACCTTTACTACTATGGCCACCAAAACCAGTCACAAGACCTGGAGTTGTCTGTGCAGATGTACGCCCAAGCCGCC CTGGATGGAGACTCCCAGTTTATTTATGTGAATCAGTCCTTTGCTCCTTCCCCAGACCAAGAAGTTGGAACTCTCTATGAGTGTTTTGGC AGTGATGGTAAACTGGTTTTACATTACTGCAAGTCTCAGGCGTGGGGATGAACCACAAAGAAAATCAACTTGCTACTACATGAAATGGAT TTTCACGGAAGAGACAGCTCTGAAAAGTTTTGATGCTTGTGGCAAGAGACTTAACAGATGTGATCTATTTAGTATGTGTCTACTCTATGT TTATGCATAAGAAAACATCCATAGCATGAATGGACTCAGAAAAATGTGATTTGTATTAATGCACCAGTCATCATAAAAGATGGTCATGAT AGTACACCCATTGCTCCTACTTGTTACTATTATTGCTGCAGATCTGCCTCCAAGGTTGAAAAGGAGACTAAGACTGTATAAACATCTTCA TTGTCAGTTCTCAAAATGACTGAAATTGTTTTCATGGTAAAAGTTAATATACTAAAGGGTTCCTTTTTTTTTAATGTTTACATTTATCTC TATGTTTACCTTTTTAGTCACATTGACCTGCTGGCTGAATACCTCAAATAGTCCAGTAGAGGGCAGTCCACCAGGCAGAAAAGGTTAGGC GTTTTGGTTTCACATCTTTGCTGGGGAATAATAGGGGAAATGGCTGTTTTTGCTAATTTTTAGCTAATATCTAGCCAGGAGAGCAAGCAC ATAGGACAGACTGAAAGACTGTAATTTTACACAATACACATGGCTTAATTATTTTATTGGGATACAGAAAAATATAAATTCTGGACAAAT AAGTCATATACCTGTTTTCAGTCCTAACATTTAAGGATTCTTGAGTCCCAATCACATAACTGTGGTGTTACTCTGTCATTTATATGGTGT CAAAAGCACTTGATGAGTAAACCCAGTAGCATCTTTTTGAGTGTTTCATAATGCATTTTCCAACTTGAAAACAATAATTGAAAAATAGCC TTATTGTATATTTTATGCCATGACTAAAAGTGCCATTTTTACTGATGCTATTAGACTGATAATTTCTTGAAGTGAAATTTAACCTTTTTT TCTCTTTAGTATTATGTTTATAATGCCATATTTTTAGAAAGCATTCCAGATCAGGCATGGTGGCTTACACCTGTAATCCCAGCACTTTGG AAGGCTGAGGTGTGGGGATTGCGTGAAGCCACAAGTTTGAGACCAGCCTGGTTAGCAAGGCAAGATCCCCAACTCTACAAAAAAATAAAA ATTAAAAAAAAATTATTAGGCTGCAGAGGCAAGAGGATCCCCTGAGCCCAGAAGTTCAAGGGTATAGTGAGTCGTGATTGTACCACTGCA TTCCTGCTGAGCAACAGAGTGAGACCCCATCTCAAAAAAGAAAAAAAAAGGCATTCTAGTAAATCGAATGTAATGTGAATGGAATTTCAA AACAGGATCTAAGATGGTATGTAGTAGAATTCAAAGTAATATCATTTTAAAGTTAAATGAGTATGGAAAAGGTCTGTTCTCTAGTTTTGT CCAGTTCAGTTTACTGAAGGAATATATTTAATTATATTCATATATTTAACAAATAAAAATATGTTGAATTTTCGTATTGTTTGCCACTGA GGGTTCAGATGATAGACCTCAAAAAATCGAAAATACTGGTTGAAATTTGTAGCATCCATTTAGTTATTCTTTTTGACCTAAATAACTTAA TAGTTTATTAAATCTAAGGTTAGCTAAATATGTAGCTAACCTTATTTGTTTTCTTTCCTAACAACTCTGAAGAATACATAGGACTTTGCA CTTTTTTTTTTTTTTTTTTTTTTTAAAGAGACAGCGTTTCGGTCTTGTTGCCCAGGCTGGACTGTAATGGCACAATCTTGGCTCATTGCA ACCTCTACCTCCCGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCACCTGCCACCACACCCGCCTAATTT TTTGTTATTTTTAGTGGAGACAGGGTTTTACCATTTTGGCCAGGCTGGTCTCAAACTCCTGACTGACCTCAGGTGATCCACCCGCCTTGG CCTCCCAAAGTGCTGGGATTATAGGTGTGAGCCACCGTGCCGGGCCTGGACTTTGTACTTTTTCAAATCATATTTAATTATTTCTTGATC TTTACTCAAAGAATTATTCTGCGCTAAATTTGCAACATTAAACAATAATTAAGCCTGGATCCGATAAGTTATTGGGTGACTAGAACCTAC AACACAATTTATTTTTAATTTAAACTCTCAAGTCTGATTAAACTTGGGGGAAAAACTGAACATTCAGGTGATATTTTAAATTTTCTTTGT GACTAAATAGATGTCATTAATATCATGCTTCATCTTACTGTGCATAGATGACCCATGGCACACAAAGTATATGTATAATATTGCAATATT GTACTTCCATCTTTAAAAGTATGCCAAAGACTTCATAATGAATTCACCATATTTAAGGAATAAGGCAAATTAATGTTTATCCGAAATCAA AATGAGATTGGATAATTCCTGGAATCTGATTTCTGTAAGTTTCAGTCCTAAAGGGACCTTAAATATCTACTAGAACGAAGTACAGTGTAT TTCTCAGATTACATGACATTAGTCAACCAATTTAGTTGTAACACAAAGTGAGAAAGCCTTAGGTGTTGAAGGAGTGTGAAAATAAAAATC TCTTTTCATGCAGTTTCTGCTTCATTTTCCAAGGATTATAATATGCTGAGTAAACTTTTGGCACTAAGGAAGCCAGCTACAGGCCACGTA ATGAAAACTATTCAGAAAACAGTTCAGCAAATACTACTATTTGAATACAGTTCAAATCGTATTTATATAAATACTCTGCCTACATTATTT AACCCAAACTGGATTATTCACCATTCTTTGAAGATGCCTTGTGTTTTCTGTTATCTACTTCTGCTCGTGCAGTTTACTTACACCTTCACC CTTTCAAATCCTAACTCTTCTTCAAGGCCTGATTCAGATTTTAACTTTTTAAAGGCTATCTGAATCATTCAAGGAGAAGATACCCTTTCT CTCATAAAAACACTTAGAGCAAACTACCACTATTAAATCACTTATTGCATACTGCCTCAGAGCCATGTGTCCAGTTATTCTGGTTTTTAT CTGGTACCCACACACACATAATACTTAGTACATTTCCTTATATGTAAATAATTAGTAATGTAACACATCGAGTGAATGAAATTGTGATTA GCAAAGTATGACAGCTAAAAACAAAGGAAATTTTGTATAGTTTAAGTTTTTGTACAGCAGAAGGTAATGGAAAATATTTGCAACATATGA CAGTGTTTTTAATGTCTTAAGTATATGAAGAATTTGTTTCAATTGGTAAGAAAAGACCAACTGAAAAATAGGCAAAACATACCAAATTTC GATTCACAAAAAGATACAAATGGCCAACAAAACATGAAACACCTTGAACCCCATTGGTTACAAAAAATACAAATAAAAACAATGCTGACT GACAATAAAAATAATGTACATCTTGCTATTAGCAGAGTTGTGGGGAAATCCTGTCATATTTTGGTGAATAGAATATGAGTTGGTATATCA CTTTTAGGGGGCCATTTGGCAATATCAAAAACCTTGAAACGTAAGTATAAACTTCAGTTTGTTCGTATAACCTGTCATTCACATATTGAG >In-frame_ENST00000399878_ENST00000509910_231N_SEL1L3_chr4_25766947_-_ATG12_chr5_115168361_length(amino acids)=1040AA_start in transcript=78_stop in transcript=3200 MHQVTCSGPDPGGLAMQRRGAGLGWPRQQQQQPPPLAVGPRAAAMVPSGGVPQGLGGRSACALLLLCYLNVVPSLGRQTSLTTSVIPKAE QSVAYKDFIYFTVFEGNVRNVSEVSVEYLCSQPCVVNLEAVVSSEFRSSIPVYKKRWKNEKHLHTSRTQIVHVKFPSIMVYRDDYFIRHS ISVSAVIVRAWITHKYSGRDWNVKWEENLLHAVAKNYTLLQTIPPFERPFKDHQVCLEWNMGYIWNLRANRIPQCPLENDVVALLGFPYA SSGENTGIVKKFPRFRNRELEATRRQRMDYPVFTVSLWLYLLHYCKANLCGILYFVDSNEMYGTPSVFLTEEGYLHIQMHLVKGEDLAVK TKFIIPLKEWFRLDISFNGGQIVVTTSIGQDLKSYHNQTISFREDFHYNDTAGYFIIGGSRYVAGIEGFFGPLKYYRLRSLHPAQIFNPL LEKQLAEQIKLYYERCAEVQEIVSVYASAAKHGGERQEACHLHNSYLDLQRRYGRPSMCRAFPWEKELKDKHPSLFQALLEMDLLTVPRN QNESVSEIGGKIFEKAVKRLSSIDGLHQISSIVPFLTDSSCCGYHKASYYLAVFYETGLNVPRDQLQGMLYSLVGGQGSERLSSMNLGYK HYQGIDNYPLDWELSYAYYSNIATKTPLDQHTLQGDQAYVETIRLKDDEILKVQTKEDGDVFMWLKHEATRGNAAAQQRLAQMLFWGQQG VAKNPEAAIEWYAKGALETEDPALIYDYAIVLFKGQGVKKNRRLALELMKKAASKGLHQAVNGLGWYYHKFKKNYAKAAKYWLKAEEMGN PDASYNLGVLHLDGIFPGVPGRNQTLAGEYFHKAAQGGHMEGTLWCSLYYITGNLETFPRDPEKAVVWAKHVAEKNGYLGHVIRKGLNAY LEGSWHEALLYYVLAAETGIEVSQTNLAHICEERPDLARRYLGVNCVWRYYNFSVFQIDAPSFAYLKMGDLYYYGHQNQSQDLELSVQMY -------------------------------------------------------------- >In-frame_ENST00000264868_ENST00000274459_231N_SEL1L3_chr4_25766947_-_ATG12_chr5_115168361_length(transcript)=6664nt_BP=2933nt TCAAAATCCATCCTGAAGGCCTGGGAGCCGGGCAGCTGCGCGGCACAACTCCAGGGGGCACACTCGCCCTGCGCCCTGCGGGAATGGCGC CCCGGCCAAAAAAGCAACCAGACAAAAACCCATTGCACGGGCGGGAACTGAATGTTGTACCATCTTTGGGTAGGCAGACTTCCCTGACGA CATCAGTGATACCCAAAGCTGAGCAGAGCGTGGCTTACAAAGACTTTATTTATTTTACTGTCTTTGAAGGAAACGTTCGCAACGTTTCTG AAGTCTCGGTTGAGTATTTATGCTCTCAGCCTTGTGTTGTCAATTTGGAAGCAGTTGTTTCATCTGAGTTCAGAAGTAGCATTCCCGTGT ACAAAAAAAGGTGGAAGAATGAGAAACATCTTCACACCAGCAGGACACAAATAGTACATGTGAAATTTCCAAGCATTATGGTTTACAGAG ATGATTATTTCATCAGACATTCCATCTCTGTATCTGCAGTGATAGTACGCGCCTGGATTACTCACAAATACAGTGGCAGAGACTGGAATG TTAAATGGGAGGAAAACTTGCTCCATGCTGTAGCAAAGAATTATACCCTCCTGCAGACCATCCCGCCTTTTGAACGCCCTTTCAAAGATC ATCAAGTGTGCCTTGAGTGGAACATGGGTTATATTTGGAACCTTCGGGCAAACAGGATTCCACAGTGTCCTCTGGAAAATGATGTGGTTG CCCTGCTTGGCTTTCCTTATGCCTCCAGTGGAGAAAACACAGGCATTGTCAAGAAGTTCCCGAGGTTTCGGAACCGAGAGCTGGAGGCCA CTCGACGCCAGAGGATGGATTACCCAGTGTTTACTGTTTCATTGTGGCTTTATTTACTCCATTATTGCAAGGCCAACCTCTGTGGGATTC TGTACTTTGTTGACTCTAATGAGATGTACGGCACACCTTCTGTATTTCTTACGGAAGAGGGCTATTTGCATATTCAGATGCATCTTGTCA AAGGGGAAGACCTTGCTGTAAAAACTAAATTCATCATACCTTTGAAGGAGTGGTTTCGACTGGATATCTCTTTTAACGGAGGCCAGATAG TAGTAACCACTAGCATTGGACAGGATTTGAAAAGCTACCACAATCAGACCATTAGCTTCCGGGAGGATTTCCATTATAATGACACAGCTG GGTACTTCATTATTGGAGGGAGCAGGTATGTGGCTGGCATTGAAGGGTTTTTTGGACCCCTGAAGTACTATCGCCTTCGCAGTCTGCACC CCGCCCAGATTTTTAATCCCCTCCTTGAGAAGCAACTTGCTGAACAAATCAAGTTATATTATGAAAGGTGTGCTGAGGTTCAAGAAATAG TATCTGTGTATGCATCTGCAGCAAAGCACGGGGGCGAGAGACAAGAAGCATGCCACCTCCACAACTCCTACCTGGACCTCCAGCGCAGGT ATGGGAGACCCTCGATGTGCAGAGCCTTCCCCTGGGAGAAGGAGCTGAAAGACAAACACCCCAGCTTGTTCCAGGCATTGCTGGAGATGG ATCTGCTGACCGTGCCAAGGAACCAAAATGAATCTGTATCAGAAATCGGTGGGAAGATATTTGAGAAGGCTGTAAAGAGACTCTCTAGCA TTGATGGTCTTCACCAAATTAGCTCTATCGTCCCCTTTCTGACGGATTCCAGCTGCTGTGGATACCATAAAGCATCCTACTACCTTGCAG TCTTTTATGAGACTGGATTAAATGTTCCTCGGGATCAGCTGCAGGGCATGTTGTATAGTTTGGTTGGAGGCCAGGGGAGTGAGAGGCTGT CTTCAATGAATCTTGGGTATAAACACTACCAGGGTATTGACAACTACCCCCTGGACTGGGAACTGTCGTATGCCTACTACAGCAACATTG CCACCAAGACACCCCTTGACCAGCACACACTGCAAGGAGATCAGGCATATGTTGAAACAATTAGACTAAAAGATGATGAAATACTCAAGG TACAAACCAAAGAAGATGGAGATGTCTTTATGTGGTTGAAGCATGAAGCTACCCGAGGCAATGCAGCAGCTCAGCAACGATTGGCCCAGA TGCTGTTCTGGGGGCAGCAAGGTGTGGCCAAGAATCCCGAAGCAGCAATTGAGTGGTACGCCAAGGGCGCCCTGGAGACGGAGGATCCTG CGTTAATCTATGACTATGCCATTGTGCTATTCAAGGGTCAAGGAGTAAAAAAGAACAGACGGCTTGCCTTAGAGCTGATGAAGAAAGCAG CTTCCAAGGGATTGCATCAGGCAGTCAATGGCCTGGGATGGTATTACCACAAATTCAAGAAAAATTACGCCAAAGCAGCAAAGTACTGGT TAAAAGCAGAAGAAATGGGGAACCCAGATGCGTCATACAATCTTGGAGTCCTGCATTTGGATGGCATCTTCCCTGGAGTTCCTGGAAGGA ATCAAACTTTAGCTGGTGAATATTTCCATAAGGCTGCGCAAGGTGGACACATGGAAGGGACCTTGTGGTGTTCTCTCTACTATATCACAG GCAACCTGGAGACATTCCCTAGAGATCCTGAGAAAGCTGTTGTATGGGCAAAACATGTAGCTGAGAAAAATGGCTACTTGGGCCATGTCA TCCGCAAAGGCCTCAATGCCTACCTGGAAGGTTCATGGCATGAAGCTTTGCTGTATTATGTTTTAGCAGCAGAAACTGGAATTGAAGTGT CACAGACAAATTTAGCACACATCTGTGAGGAGAGGCCAGACCTGGCCAGGAGATACTTGGGTGTTAACTGTGTTTGGAGATACTATAATT TCTCTGTTTTTCAAATCGATGCTCCTTCCTTTGCATATTTGAAGATGGGAGACCTTTACTACTATGGCCACCAAAACCAGTCACAAGACC TGGAGTTGTCTGTGCAGATGTACGCCCAAGCCGCCCTGGATGGAGACTCCCAGTTTATTTATGTGAATCAGTCCTTTGCTCCTTCCCCAG ACCAAGAAGTTGGAACTCTCTATGAGTGTTTTGGCAGTGATGGTAAACTGGTTTTACATTACTGCAAGTCTCAGGCGTGGGGATGAACCA CAAAGAAAATCAACTTGCTACTACATGAAATGGATTTTCACGGAAGAGACAGCTCTGAAAAGTTTTGATGCTTGTGGCAAGAGACTTAAC AGATGTGATCTATTTAGTATGTGTCTACTCTATGTTTATGCATAAGAAAACATCCATAGCATGAATGGACTCAGAAAAATGTGATTTGTA TTAATGCACCAGTCATCATAAAAGATGGTCATGATAGTACACCCATTGCTCCTACTTGTTACTATTATTGCTGCAGATCTGCCTCCAAGG TTGAAAAGGAGACTAAGACTGTATAAACATCTTCATTGTCAGTTCTCAAAATGACTGAAATTGTTTTCATGGTAAAAGTTAATATACTAA AGGGTTCCTTTTTTTTTAATGTTTACATTTATCTCTATGTTTACCTTTTTAGTCACATTGACCTGCTGGCTGAATACCTCAAATAGTCCA GTAGAGGGCAGTCCACCAGGCAGAAAAGGTTAGGCGTTTTGGTTTCACATCTTTGCTGGGGAATAATAGGGGAAATGGCTGTTTTTGCTA ATTTTTAGCTAATATCTAGCCAGGAGAGCAAGCACATAGGACAGACTGAAAGACTGTAATTTTACACAATACACATGGCTTAATTATTTT ATTGGGATACAGAAAAATATAAATTCTGGACAAATAAGTCATATACCTGTTTTCAGTCCTAACATTTAAGGATTCTTGAGTCCCAATCAC ATAACTGTGGTGTTACTCTGTCATTTATATGGTGTCAAAAGCACTTGATGAGTAAACCCAGTAGCATCTTTTTGAGTGTTTCATAATGCA TTTTCCAACTTGAAAACAATAATTGAAAAATAGCCTTATTGTATATTTTATGCCATGACTAAAAGTGCCATTTTTACTGATGCTATTAGA CTGATAATTTCTTGAAGTGAAATTTAACCTTTTTTTCTCTTTAGTATTATGTTTATAATGCCATATTTTTAGAAAGCATTCCAGATCAGG CATGGTGGCTTACACCTGTAATCCCAGCACTTTGGAAGGCTGAGGTGTGGGGATTGCGTGAAGCCACAAGTTTGAGACCAGCCTGGTTAG CAAGGCAAGATCCCCAACTCTACAAAAAAATAAAAATTAAAAAAAAATTATTAGGCTGCAGAGGCAAGAGGATCCCCTGAGCCCAGAAGT TCAAGGGTATAGTGAGTCGTGATTGTACCACTGCATTCCTGCTGAGCAACAGAGTGAGACCCCATCTCAAAAAAGAAAAAAAAAGGCATT CTAGTAAATCGAATGTAATGTGAATGGAATTTCAAAACAGGATCTAAGATGGTATGTAGTAGAATTCAAAGTAATATCATTTTAAAGTTA AATGAGTATGGAAAAGGTCTGTTCTCTAGTTTTGTCCAGTTCAGTTTACTGAAGGAATATATTTAATTATATTCATATATTTAACAAATA AAAATATGTTGAATTTTCGTATTGTTTGCCACTGAGGGTTCAGATGATAGACCTCAAAAAATCGAAAATACTGGTTGAAATTTGTAGCAT CCATTTAGTTATTCTTTTTGACCTAAATAACTTAATAGTTTATTAAATCTAAGGTTAGCTAAATATGTAGCTAACCTTATTTGTTTTCTT TCCTAACAACTCTGAAGAATACATAGGACTTTGCACTTTTTTTTTTTTTTTTTTTTTTTAAAGAGACAGCGTTTCGGTCTTGTTGCCCAG GCTGGACTGTAATGGCACAATCTTGGCTCATTGCAACCTCTACCTCCCGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGG GATTACAGGCACCTGCCACCACACCCGCCTAATTTTTTGTTATTTTTAGTGGAGACAGGGTTTTACCATTTTGGCCAGGCTGGTCTCAAA CTCCTGACTGACCTCAGGTGATCCACCCGCCTTGGCCTCCCAAAGTGCTGGGATTATAGGTGTGAGCCACCGTGCCGGGCCTGGACTTTG TACTTTTTCAAATCATATTTAATTATTTCTTGATCTTTACTCAAAGAATTATTCTGCGCTAAATTTGCAACATTAAACAATAATTAAGCC TGGATCCGATAAGTTATTGGGTGACTAGAACCTACAACACAATTTATTTTTAATTTAAACTCTCAAGTCTGATTAAACTTGGGGGAAAAA CTGAACATTCAGGTGATATTTTAAATTTTCTTTGTGACTAAATAGATGTCATTAATATCATGCTTCATCTTACTGTGCATAGATGACCCA TGGCACACAAAGTATATGTATAATATTGCAATATTGTACTTCCATCTTTAAAAGTATGCCAAAGACTTCATAATGAATTCACCATATTTA AGGAATAAGGCAAATTAATGTTTATCCGAAATCAAAATGAGATTGGATAATTCCTGGAATCTGATTTCTGTAAGTTTCAGTCCTAAAGGG ACCTTAAATATCTACTAGAACGAAGTACAGTGTATTTCTCAGATTACATGACATTAGTCAACCAATTTAGTTGTAACACAAAGTGAGAAA GCCTTAGGTGTTGAAGGAGTGTGAAAATAAAAATCTCTTTTCATGCAGTTTCTGCTTCATTTTCCAAGGATTATAATATGCTGAGTAAAC TTTTGGCACTAAGGAAGCCAGCTACAGGCCACGTAATGAAAACTATTCAGAAAACAGTTCAGCAAATACTACTATTTGAATACAGTTCAA ATCGTATTTATATAAATACTCTGCCTACATTATTTAACCCAAACTGGATTATTCACCATTCTTTGAAGATGCCTTGTGTTTTCTGTTATC TACTTCTGCTCGTGCAGTTTACTTACACCTTCACCCTTTCAAATCCTAACTCTTCTTCAAGGCCTGATTCAGATTTTAACTTTTTAAAGG CTATCTGAATCATTCAAGGAGAAGATACCCTTTCTCTCATAAAAACACTTAGAGCAAACTACCACTATTAAATCACTTATTGCATACTGC CTCAGAGCCATGTGTCCAGTTATTCTGGTTTTTATCTGGTACCCACACACACATAATACTTAGTACATTTCCTTATATGTAAATAATTAG TAATGTAACACATCGAGTGAATGAAATTGTGATTAGCAAAGTATGACAGCTAAAAACAAAGGAAATTTTGTATAGTTTAAGTTTTTGTAC AGCAGAAGGTAATGGAAAATATTTGCAACATATGACAGTGTTTTTAATGTCTTAAGTATATGAAGAATTTGTTTCAATTGGTAAGAAAAG ACCAACTGAAAAATAGGCAAAACATACCAAATTTCGATTCACAAAAAGATACAAATGGCCAACAAAACATGAAACACCTTGAACCCCATT GGTTACAAAAAATACAAATAAAAACAATGCTGACTGACAATAAAAATAATGTACATCTTGCTATTAGCAGAGTTGTGGGGAAATCCTGTC ATATTTTGGTGAATAGAATATGAGTTGGTATATCACTTTTAGGGGGCCATTTGGCAATATCAAAAACCTTGAAACGTAAGTATAAACTTC AGTTTGTTCGTATAACCTGTCATTCACATATTGAGTGCCTACTATGTCCTAAATATTGGAATAACACTAATAAAGCTCATAAGAGACTAA >In-frame_ENST00000264868_ENST00000274459_231N_SEL1L3_chr4_25766947_-_ATG12_chr5_115168361_length(amino acids)=1011AA_start in transcript=20_stop in transcript=3055 MGAGQLRGTTPGGTLALRPAGMAPRPKKQPDKNPLHGRELNVVPSLGRQTSLTTSVIPKAEQSVAYKDFIYFTVFEGNVRNVSEVSVEYL CSQPCVVNLEAVVSSEFRSSIPVYKKRWKNEKHLHTSRTQIVHVKFPSIMVYRDDYFIRHSISVSAVIVRAWITHKYSGRDWNVKWEENL LHAVAKNYTLLQTIPPFERPFKDHQVCLEWNMGYIWNLRANRIPQCPLENDVVALLGFPYASSGENTGIVKKFPRFRNRELEATRRQRMD YPVFTVSLWLYLLHYCKANLCGILYFVDSNEMYGTPSVFLTEEGYLHIQMHLVKGEDLAVKTKFIIPLKEWFRLDISFNGGQIVVTTSIG QDLKSYHNQTISFREDFHYNDTAGYFIIGGSRYVAGIEGFFGPLKYYRLRSLHPAQIFNPLLEKQLAEQIKLYYERCAEVQEIVSVYASA AKHGGERQEACHLHNSYLDLQRRYGRPSMCRAFPWEKELKDKHPSLFQALLEMDLLTVPRNQNESVSEIGGKIFEKAVKRLSSIDGLHQI SSIVPFLTDSSCCGYHKASYYLAVFYETGLNVPRDQLQGMLYSLVGGQGSERLSSMNLGYKHYQGIDNYPLDWELSYAYYSNIATKTPLD QHTLQGDQAYVETIRLKDDEILKVQTKEDGDVFMWLKHEATRGNAAAQQRLAQMLFWGQQGVAKNPEAAIEWYAKGALETEDPALIYDYA IVLFKGQGVKKNRRLALELMKKAASKGLHQAVNGLGWYYHKFKKNYAKAAKYWLKAEEMGNPDASYNLGVLHLDGIFPGVPGRNQTLAGE YFHKAAQGGHMEGTLWCSLYYITGNLETFPRDPEKAVVWAKHVAEKNGYLGHVIRKGLNAYLEGSWHEALLYYVLAAETGIEVSQTNLAH ICEERPDLARRYLGVNCVWRYYNFSVFQIDAPSFAYLKMGDLYYYGHQNQSQDLELSVQMYAQAALDGDSQFIYVNQSFAPSPDQEVGTL -------------------------------------------------------------- >In-frame_ENST00000264868_ENST00000509910_231N_SEL1L3_chr4_25766947_-_ATG12_chr5_115168361_length(transcript)=6660nt_BP=2933nt TCAAAATCCATCCTGAAGGCCTGGGAGCCGGGCAGCTGCGCGGCACAACTCCAGGGGGCACACTCGCCCTGCGCCCTGCGGGAATGGCGC CCCGGCCAAAAAAGCAACCAGACAAAAACCCATTGCACGGGCGGGAACTGAATGTTGTACCATCTTTGGGTAGGCAGACTTCCCTGACGA CATCAGTGATACCCAAAGCTGAGCAGAGCGTGGCTTACAAAGACTTTATTTATTTTACTGTCTTTGAAGGAAACGTTCGCAACGTTTCTG AAGTCTCGGTTGAGTATTTATGCTCTCAGCCTTGTGTTGTCAATTTGGAAGCAGTTGTTTCATCTGAGTTCAGAAGTAGCATTCCCGTGT ACAAAAAAAGGTGGAAGAATGAGAAACATCTTCACACCAGCAGGACACAAATAGTACATGTGAAATTTCCAAGCATTATGGTTTACAGAG ATGATTATTTCATCAGACATTCCATCTCTGTATCTGCAGTGATAGTACGCGCCTGGATTACTCACAAATACAGTGGCAGAGACTGGAATG TTAAATGGGAGGAAAACTTGCTCCATGCTGTAGCAAAGAATTATACCCTCCTGCAGACCATCCCGCCTTTTGAACGCCCTTTCAAAGATC ATCAAGTGTGCCTTGAGTGGAACATGGGTTATATTTGGAACCTTCGGGCAAACAGGATTCCACAGTGTCCTCTGGAAAATGATGTGGTTG CCCTGCTTGGCTTTCCTTATGCCTCCAGTGGAGAAAACACAGGCATTGTCAAGAAGTTCCCGAGGTTTCGGAACCGAGAGCTGGAGGCCA CTCGACGCCAGAGGATGGATTACCCAGTGTTTACTGTTTCATTGTGGCTTTATTTACTCCATTATTGCAAGGCCAACCTCTGTGGGATTC TGTACTTTGTTGACTCTAATGAGATGTACGGCACACCTTCTGTATTTCTTACGGAAGAGGGCTATTTGCATATTCAGATGCATCTTGTCA AAGGGGAAGACCTTGCTGTAAAAACTAAATTCATCATACCTTTGAAGGAGTGGTTTCGACTGGATATCTCTTTTAACGGAGGCCAGATAG TAGTAACCACTAGCATTGGACAGGATTTGAAAAGCTACCACAATCAGACCATTAGCTTCCGGGAGGATTTCCATTATAATGACACAGCTG GGTACTTCATTATTGGAGGGAGCAGGTATGTGGCTGGCATTGAAGGGTTTTTTGGACCCCTGAAGTACTATCGCCTTCGCAGTCTGCACC CCGCCCAGATTTTTAATCCCCTCCTTGAGAAGCAACTTGCTGAACAAATCAAGTTATATTATGAAAGGTGTGCTGAGGTTCAAGAAATAG TATCTGTGTATGCATCTGCAGCAAAGCACGGGGGCGAGAGACAAGAAGCATGCCACCTCCACAACTCCTACCTGGACCTCCAGCGCAGGT ATGGGAGACCCTCGATGTGCAGAGCCTTCCCCTGGGAGAAGGAGCTGAAAGACAAACACCCCAGCTTGTTCCAGGCATTGCTGGAGATGG ATCTGCTGACCGTGCCAAGGAACCAAAATGAATCTGTATCAGAAATCGGTGGGAAGATATTTGAGAAGGCTGTAAAGAGACTCTCTAGCA TTGATGGTCTTCACCAAATTAGCTCTATCGTCCCCTTTCTGACGGATTCCAGCTGCTGTGGATACCATAAAGCATCCTACTACCTTGCAG TCTTTTATGAGACTGGATTAAATGTTCCTCGGGATCAGCTGCAGGGCATGTTGTATAGTTTGGTTGGAGGCCAGGGGAGTGAGAGGCTGT CTTCAATGAATCTTGGGTATAAACACTACCAGGGTATTGACAACTACCCCCTGGACTGGGAACTGTCGTATGCCTACTACAGCAACATTG CCACCAAGACACCCCTTGACCAGCACACACTGCAAGGAGATCAGGCATATGTTGAAACAATTAGACTAAAAGATGATGAAATACTCAAGG TACAAACCAAAGAAGATGGAGATGTCTTTATGTGGTTGAAGCATGAAGCTACCCGAGGCAATGCAGCAGCTCAGCAACGATTGGCCCAGA TGCTGTTCTGGGGGCAGCAAGGTGTGGCCAAGAATCCCGAAGCAGCAATTGAGTGGTACGCCAAGGGCGCCCTGGAGACGGAGGATCCTG CGTTAATCTATGACTATGCCATTGTGCTATTCAAGGGTCAAGGAGTAAAAAAGAACAGACGGCTTGCCTTAGAGCTGATGAAGAAAGCAG CTTCCAAGGGATTGCATCAGGCAGTCAATGGCCTGGGATGGTATTACCACAAATTCAAGAAAAATTACGCCAAAGCAGCAAAGTACTGGT TAAAAGCAGAAGAAATGGGGAACCCAGATGCGTCATACAATCTTGGAGTCCTGCATTTGGATGGCATCTTCCCTGGAGTTCCTGGAAGGA ATCAAACTTTAGCTGGTGAATATTTCCATAAGGCTGCGCAAGGTGGACACATGGAAGGGACCTTGTGGTGTTCTCTCTACTATATCACAG GCAACCTGGAGACATTCCCTAGAGATCCTGAGAAAGCTGTTGTATGGGCAAAACATGTAGCTGAGAAAAATGGCTACTTGGGCCATGTCA TCCGCAAAGGCCTCAATGCCTACCTGGAAGGTTCATGGCATGAAGCTTTGCTGTATTATGTTTTAGCAGCAGAAACTGGAATTGAAGTGT CACAGACAAATTTAGCACACATCTGTGAGGAGAGGCCAGACCTGGCCAGGAGATACTTGGGTGTTAACTGTGTTTGGAGATACTATAATT TCTCTGTTTTTCAAATCGATGCTCCTTCCTTTGCATATTTGAAGATGGGAGACCTTTACTACTATGGCCACCAAAACCAGTCACAAGACC TGGAGTTGTCTGTGCAGATGTACGCCCAAGCCGCCCTGGATGGAGACTCCCAGTTTATTTATGTGAATCAGTCCTTTGCTCCTTCCCCAG ACCAAGAAGTTGGAACTCTCTATGAGTGTTTTGGCAGTGATGGTAAACTGGTTTTACATTACTGCAAGTCTCAGGCGTGGGGATGAACCA CAAAGAAAATCAACTTGCTACTACATGAAATGGATTTTCACGGAAGAGACAGCTCTGAAAAGTTTTGATGCTTGTGGCAAGAGACTTAAC AGATGTGATCTATTTAGTATGTGTCTACTCTATGTTTATGCATAAGAAAACATCCATAGCATGAATGGACTCAGAAAAATGTGATTTGTA TTAATGCACCAGTCATCATAAAAGATGGTCATGATAGTACACCCATTGCTCCTACTTGTTACTATTATTGCTGCAGATCTGCCTCCAAGG TTGAAAAGGAGACTAAGACTGTATAAACATCTTCATTGTCAGTTCTCAAAATGACTGAAATTGTTTTCATGGTAAAAGTTAATATACTAA AGGGTTCCTTTTTTTTTAATGTTTACATTTATCTCTATGTTTACCTTTTTAGTCACATTGACCTGCTGGCTGAATACCTCAAATAGTCCA GTAGAGGGCAGTCCACCAGGCAGAAAAGGTTAGGCGTTTTGGTTTCACATCTTTGCTGGGGAATAATAGGGGAAATGGCTGTTTTTGCTA ATTTTTAGCTAATATCTAGCCAGGAGAGCAAGCACATAGGACAGACTGAAAGACTGTAATTTTACACAATACACATGGCTTAATTATTTT ATTGGGATACAGAAAAATATAAATTCTGGACAAATAAGTCATATACCTGTTTTCAGTCCTAACATTTAAGGATTCTTGAGTCCCAATCAC ATAACTGTGGTGTTACTCTGTCATTTATATGGTGTCAAAAGCACTTGATGAGTAAACCCAGTAGCATCTTTTTGAGTGTTTCATAATGCA TTTTCCAACTTGAAAACAATAATTGAAAAATAGCCTTATTGTATATTTTATGCCATGACTAAAAGTGCCATTTTTACTGATGCTATTAGA CTGATAATTTCTTGAAGTGAAATTTAACCTTTTTTTCTCTTTAGTATTATGTTTATAATGCCATATTTTTAGAAAGCATTCCAGATCAGG CATGGTGGCTTACACCTGTAATCCCAGCACTTTGGAAGGCTGAGGTGTGGGGATTGCGTGAAGCCACAAGTTTGAGACCAGCCTGGTTAG CAAGGCAAGATCCCCAACTCTACAAAAAAATAAAAATTAAAAAAAAATTATTAGGCTGCAGAGGCAAGAGGATCCCCTGAGCCCAGAAGT TCAAGGGTATAGTGAGTCGTGATTGTACCACTGCATTCCTGCTGAGCAACAGAGTGAGACCCCATCTCAAAAAAGAAAAAAAAAGGCATT CTAGTAAATCGAATGTAATGTGAATGGAATTTCAAAACAGGATCTAAGATGGTATGTAGTAGAATTCAAAGTAATATCATTTTAAAGTTA AATGAGTATGGAAAAGGTCTGTTCTCTAGTTTTGTCCAGTTCAGTTTACTGAAGGAATATATTTAATTATATTCATATATTTAACAAATA AAAATATGTTGAATTTTCGTATTGTTTGCCACTGAGGGTTCAGATGATAGACCTCAAAAAATCGAAAATACTGGTTGAAATTTGTAGCAT CCATTTAGTTATTCTTTTTGACCTAAATAACTTAATAGTTTATTAAATCTAAGGTTAGCTAAATATGTAGCTAACCTTATTTGTTTTCTT TCCTAACAACTCTGAAGAATACATAGGACTTTGCACTTTTTTTTTTTTTTTTTTTTTTTAAAGAGACAGCGTTTCGGTCTTGTTGCCCAG GCTGGACTGTAATGGCACAATCTTGGCTCATTGCAACCTCTACCTCCCGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGG GATTACAGGCACCTGCCACCACACCCGCCTAATTTTTTGTTATTTTTAGTGGAGACAGGGTTTTACCATTTTGGCCAGGCTGGTCTCAAA CTCCTGACTGACCTCAGGTGATCCACCCGCCTTGGCCTCCCAAAGTGCTGGGATTATAGGTGTGAGCCACCGTGCCGGGCCTGGACTTTG TACTTTTTCAAATCATATTTAATTATTTCTTGATCTTTACTCAAAGAATTATTCTGCGCTAAATTTGCAACATTAAACAATAATTAAGCC TGGATCCGATAAGTTATTGGGTGACTAGAACCTACAACACAATTTATTTTTAATTTAAACTCTCAAGTCTGATTAAACTTGGGGGAAAAA CTGAACATTCAGGTGATATTTTAAATTTTCTTTGTGACTAAATAGATGTCATTAATATCATGCTTCATCTTACTGTGCATAGATGACCCA TGGCACACAAAGTATATGTATAATATTGCAATATTGTACTTCCATCTTTAAAAGTATGCCAAAGACTTCATAATGAATTCACCATATTTA AGGAATAAGGCAAATTAATGTTTATCCGAAATCAAAATGAGATTGGATAATTCCTGGAATCTGATTTCTGTAAGTTTCAGTCCTAAAGGG ACCTTAAATATCTACTAGAACGAAGTACAGTGTATTTCTCAGATTACATGACATTAGTCAACCAATTTAGTTGTAACACAAAGTGAGAAA GCCTTAGGTGTTGAAGGAGTGTGAAAATAAAAATCTCTTTTCATGCAGTTTCTGCTTCATTTTCCAAGGATTATAATATGCTGAGTAAAC TTTTGGCACTAAGGAAGCCAGCTACAGGCCACGTAATGAAAACTATTCAGAAAACAGTTCAGCAAATACTACTATTTGAATACAGTTCAA ATCGTATTTATATAAATACTCTGCCTACATTATTTAACCCAAACTGGATTATTCACCATTCTTTGAAGATGCCTTGTGTTTTCTGTTATC TACTTCTGCTCGTGCAGTTTACTTACACCTTCACCCTTTCAAATCCTAACTCTTCTTCAAGGCCTGATTCAGATTTTAACTTTTTAAAGG CTATCTGAATCATTCAAGGAGAAGATACCCTTTCTCTCATAAAAACACTTAGAGCAAACTACCACTATTAAATCACTTATTGCATACTGC CTCAGAGCCATGTGTCCAGTTATTCTGGTTTTTATCTGGTACCCACACACACATAATACTTAGTACATTTCCTTATATGTAAATAATTAG TAATGTAACACATCGAGTGAATGAAATTGTGATTAGCAAAGTATGACAGCTAAAAACAAAGGAAATTTTGTATAGTTTAAGTTTTTGTAC AGCAGAAGGTAATGGAAAATATTTGCAACATATGACAGTGTTTTTAATGTCTTAAGTATATGAAGAATTTGTTTCAATTGGTAAGAAAAG ACCAACTGAAAAATAGGCAAAACATACCAAATTTCGATTCACAAAAAGATACAAATGGCCAACAAAACATGAAACACCTTGAACCCCATT GGTTACAAAAAATACAAATAAAAACAATGCTGACTGACAATAAAAATAATGTACATCTTGCTATTAGCAGAGTTGTGGGGAAATCCTGTC ATATTTTGGTGAATAGAATATGAGTTGGTATATCACTTTTAGGGGGCCATTTGGCAATATCAAAAACCTTGAAACGTAAGTATAAACTTC AGTTTGTTCGTATAACCTGTCATTCACATATTGAGTGCCTACTATGTCCTAAATATTGGAATAACACTAATAAAGCTCATAAGAGACTAA >In-frame_ENST00000264868_ENST00000509910_231N_SEL1L3_chr4_25766947_-_ATG12_chr5_115168361_length(amino acids)=1011AA_start in transcript=20_stop in transcript=3055 MGAGQLRGTTPGGTLALRPAGMAPRPKKQPDKNPLHGRELNVVPSLGRQTSLTTSVIPKAEQSVAYKDFIYFTVFEGNVRNVSEVSVEYL CSQPCVVNLEAVVSSEFRSSIPVYKKRWKNEKHLHTSRTQIVHVKFPSIMVYRDDYFIRHSISVSAVIVRAWITHKYSGRDWNVKWEENL LHAVAKNYTLLQTIPPFERPFKDHQVCLEWNMGYIWNLRANRIPQCPLENDVVALLGFPYASSGENTGIVKKFPRFRNRELEATRRQRMD YPVFTVSLWLYLLHYCKANLCGILYFVDSNEMYGTPSVFLTEEGYLHIQMHLVKGEDLAVKTKFIIPLKEWFRLDISFNGGQIVVTTSIG QDLKSYHNQTISFREDFHYNDTAGYFIIGGSRYVAGIEGFFGPLKYYRLRSLHPAQIFNPLLEKQLAEQIKLYYERCAEVQEIVSVYASA AKHGGERQEACHLHNSYLDLQRRYGRPSMCRAFPWEKELKDKHPSLFQALLEMDLLTVPRNQNESVSEIGGKIFEKAVKRLSSIDGLHQI SSIVPFLTDSSCCGYHKASYYLAVFYETGLNVPRDQLQGMLYSLVGGQGSERLSSMNLGYKHYQGIDNYPLDWELSYAYYSNIATKTPLD QHTLQGDQAYVETIRLKDDEILKVQTKEDGDVFMWLKHEATRGNAAAQQRLAQMLFWGQQGVAKNPEAAIEWYAKGALETEDPALIYDYA IVLFKGQGVKKNRRLALELMKKAASKGLHQAVNGLGWYYHKFKKNYAKAAKYWLKAEEMGNPDASYNLGVLHLDGIFPGVPGRNQTLAGE YFHKAAQGGHMEGTLWCSLYYITGNLETFPRDPEKAVVWAKHVAEKNGYLGHVIRKGLNAYLEGSWHEALLYYVLAAETGIEVSQTNLAH ICEERPDLARRYLGVNCVWRYYNFSVFQIDAPSFAYLKMGDLYYYGHQNQSQDLELSVQMYAQAALDGDSQFIYVNQSFAPSPDQEVGTL -------------------------------------------------------------- >In-frame_ENST00000502949_ENST00000500945_231N_SEL1L3_chr4_25766947_-_ATG12_chr5_115168361_length(transcript)=4151nt_BP=2897nt CACACTCGCCCTGCGCCCTGCGGGAATGGCGCCCCGGCCAAAAAAGCAACCAGACAAAAACCCATTGCACGGGCGGGAACTGGTCTGTGC GACCCGCAAAAGGGAATGTTGTACCATCTTTGGGTAGGCAGACTTCCCTGACGACATCAGTGATACCCAAAGCTGAGCAGAGCGTGGCTT ACAAAGACTTTATTTATTTTACTGTCTTTGAAGGAAACGTTCGCAACGTTTCTGAAGTCTCGGTTGAGTATTTATGCTCTCAGCCTTGTG TTGTCAATTTGGAAGCAGTTGTTTCATCTGAGTTCAGAAGTAGCATTCCCGTGTACAAAAAAAGGTGGAAGAATGAGAAACATCTTCACA CCAGCAGGACACAAATAGTACATGTGAAATTTCCAAGCATTATGGTTTACAGAGATGATTATTTCATCAGACATTCCATCTCTGTATCTG CAGTGATAGTACGCGCCTGGATTACTCACAAATACAGTGGCAGAGACTGGAATGTTAAATGGGAGGAAAACTTGCTCCATGCTGTAGCAA AGAATTATACCCTCCTGCAGACCATCCCGCCTTTTGAACGCCCTTTCAAAGATCATCAAGTGTGCCTTGAGTGGAACATGGGTTATATTT GGAACCTTCGGGCAAACAGGATTCCACAGTGTCCTCTGGAAAATGATGTGGTTGCCCTGCTTGGCTTTCCTTATGCCTCCAGTGGAGAAA ACACAGGCATTGTCAAGAAGTTCCCGAGGTTTCGGAACCGAGAGCTGGAGGCCACTCGACGCCAGAGGATGGATTACCCAGTGTTTACTG TTTCATTGTGGCTTTATTTACTCCATTATTGCAAGGCCAACCTCTGTGGGATTCTGTACTTTGTTGACTCTAATGAGATGTACGGCACAC CTTCTGTATTTCTTACGGAAGAGGGCTATTTGCATATTCAGATGCATCTTGTCAAAGGGGAAGACCTTGCTGTAAAAACTAAATTCATCA TACCTTTGAAGGAGTGGTTTCGACTGGATATCTCTTTTAACGGAGGCCAGATAGTAGTAACCACTAGCATTGGACAGGATTTGAAAAGCT ACCACAATCAGACCATTAGCTTCCGGGAGGATTTCCATTATAATGACACAGCTGGGTACTTCATTATTGGAGGGAGCAGGTATGTGGCTG GCATTGAAGGGTTTTTTGGACCCCTGAAGTACTATCGCCTTCGCAGTCTGCACCCCGCCCAGATTTTTAATCCCCTCCTTGAGAAGCAAC TTGCTGAACAAATCAAGTTATATTATGAAAGGTGTGCTGAGGTTCAAGAAATAGTATCTGTGTATGCATCTGCAGCAAAGCACGGGGGCG AGAGACAAGAAGCATGCCACCTCCACAACTCCTACCTGGACCTCCAGCGCAGGTATGGGAGACCCTCGATGTGCAGAGCCTTCCCCTGGG AGAAGGAGCTGAAAGACAAACACCCCAGCTTGTTCCAGGCATTGCTGGAGATGGATCTGCTGACCGTGCCAAGGAACCAAAATGAATCTG TATCAGAAATCGGTGGGAAGATATTTGAGAAGGCTGTAAAGAGACTCTCTAGCATTGATGGTCTTCACCAAATTAGCTCTATCGTCCCCT TTCTGACGGATTCCAGCTGCTGTGGATACCATAAAGCATCCTACTACCTTGCAGTCTTTTATGAGACTGGATTAAATGTTCCTCGGGATC AGCTGCAGGGCATGTTGTATAGTTTGGTTGGAGGCCAGGGGAGTGAGAGGCTGTCTTCAATGAATCTTGGGTATAAACACTACCAGGGTA TTGACAACTACCCCCTGGACTGGGAACTGTCGTATGCCTACTACAGCAACATTGCCACCAAGACACCCCTTGACCAGCACACACTGCAAG GAGATCAGGCATATGTTGAAACAATTAGACTAAAAGATGATGAAATACTCAAGGTACAAACCAAAGAAGATGGAGATGTCTTTATGTGGT TGAAGCATGAAGCTACCCGAGGCAATGCAGCAGCTCAGCAACGATTGGCCCAGATGCTGTTCTGGGGGCAGCAAGGTGTGGCCAAGAATC CCGAAGCAGCAATTGAGTGGTACGCCAAGGGCGCCCTGGAGACGGAGGATCCTGCGTTAATCTATGACTATGCCATTGTGCTATTCAAGG GTCAAGGAGTAAAAAAGAACAGACGGCTTGCCTTAGAGCTGATGAAGAAAGCAGCTTCCAAGGGATTGCATCAGGCAGTCAATGGCCTGG GATGGTATTACCACAAATTCAAGAAAAATTACGCCAAAGCAGCAAAGTACTGGTTAAAAGCAGAAGAAATGGGGAACCCAGATGCGTCAT ACAATCTTGGAGTCCTGCATTTGGATGGCATCTTCCCTGGAGTTCCTGGAAGGAATCAAACTTTAGCTGGTGAATATTTCCATAAGGCTG CGCAAGGTGGACACATGGAAGGGACCTTGTGGTGTTCTCTCTACTATATCACAGGCAACCTGGAGACATTCCCTAGAGATCCTGAGAAAG CTGTTGTATGGGCAAAACATGTAGCTGAGAAAAATGGCTACTTGGGCCATGTCATCCGCAAAGGCCTCAATGCCTACCTGGAAGGTTCAT GGCATGAAGCTTTGCTGTATTATGTTTTAGCAGCAGAAACTGGAATTGAAGTGTCACAGACAAATTTAGCACACATCTGTGAGGAGAGGC CAGACCTGGCCAGGAGATACTTGGGTGTTAACTGTGTTTGGAGATACTATAATTTCTCTGTTTTTCAAATCGATGCTCCTTCCTTTGCAT ATTTGAAGATGGGAGACCTTTACTACTATGGCCACCAAAACCAGTCACAAGACCTGGAGTTGTCTGTGCAGATGTACGCCCAAGCCGCCC TGGATGGAGACTCCCAGTTTATTTATGTGAATCAGTCCTTTGCTCCTTCCCCAGACCAAGAAGTTGGAACTCTCTATGAGTGTTTTGGCA GTGATGGTAAACTGGTTTTACATTACTGCAAGTCTCAGGCGTGGGGATGAACCACAAAGAAAATCAACTTGCTACTACATGAAATGGATT TTCACGGAAGAGACAGCTCTGAAAAGTTTTGATGCTTGTGGCAAGAGACTTAACAGATGTGATCTATTTAGTATGTGTCTACTCTATGTT TATGCATAAGAAAACATCCATAGCATGAATGGACTCAGAAAAATGTGATTTGTATTAATGCACCAGTCATCATAAAAGATGGTCATGATA GTACACCCATTGCTCCTACTTGTTACTATTATTGCTGCAGATCTGCCTCCAAGGTTGAAAAGGAGACTAAGACTGTATAAACATCTTCAT TGTCAGTTCTCAAAATGACTGAAATTGTTTTCATGGTAAAAGTTAATATACTAAAGGGTTCCTTTTTTTTTAATGTTTACATTTATCTCT ATGTTTACCTTTTTAGTCACATTGACCTGCTGGCTGAATACCTCAAATAGTCCAGTAGAGGGCAGTCCACCAGGCAGAAAAGGTTAGGCG TTTTGGTTTCACATCTTTGCTGGGGAATAATAGGGGAAATGGCTGTTTTTGCTAATTTTTAGCTAATATCTAGCCAGGAGAGCAAGCACA TAGGACAGACTGAAAGACTGTAATTTTACACAATACACATGGCTTAATTATTTTATTGGGATACAGAAAAATATAAATTCTGGACAAATA AGTCATATACCTGTTTTCAGTCCTAACATTTAAGGATTCTTGAGTCCCAATCACATAACTGTGGTGTTACTCTGTCATTTATATGGTGTC AAAAGCACTTGATGAGTAAACCCAGTAGCATCTTTTTGAGTGTTTCATAATGCATTTTCCAACTTGAAAACAATAATTGAAAAATAGCCT TATTGTATATTTTATGCCATGACTAAAAGTGCCATTTTTACTGATGCTATTAGACTGATAATTTCTTGAAGTGAAATTTAACCTTTTTTT CTCTTTAGTATTATGTTTATAATGCCATATTTTTAGAAAGCATTCCAGATCAGGCATGGTGGCTTACACCTGTAATCCCAGCACTTTGGA AGGCTGAGGTGTGGGGATTGCGTGAAGCCACAAGTTTGAGACCAGCCTGGTTAGCAAGGCAAGATCCCCAACTCTACAAAAAAATAAAAA >In-frame_ENST00000502949_ENST00000500945_231N_SEL1L3_chr4_25766947_-_ATG12_chr5_115168361_length(amino acids)=1000AA_start in transcript=17_stop in transcript=3019 MREWRPGQKSNQTKTHCTGGNWSVRPAKGNVVPSLGRQTSLTTSVIPKAEQSVAYKDFIYFTVFEGNVRNVSEVSVEYLCSQPCVVNLEA VVSSEFRSSIPVYKKRWKNEKHLHTSRTQIVHVKFPSIMVYRDDYFIRHSISVSAVIVRAWITHKYSGRDWNVKWEENLLHAVAKNYTLL QTIPPFERPFKDHQVCLEWNMGYIWNLRANRIPQCPLENDVVALLGFPYASSGENTGIVKKFPRFRNRELEATRRQRMDYPVFTVSLWLY LLHYCKANLCGILYFVDSNEMYGTPSVFLTEEGYLHIQMHLVKGEDLAVKTKFIIPLKEWFRLDISFNGGQIVVTTSIGQDLKSYHNQTI SFREDFHYNDTAGYFIIGGSRYVAGIEGFFGPLKYYRLRSLHPAQIFNPLLEKQLAEQIKLYYERCAEVQEIVSVYASAAKHGGERQEAC HLHNSYLDLQRRYGRPSMCRAFPWEKELKDKHPSLFQALLEMDLLTVPRNQNESVSEIGGKIFEKAVKRLSSIDGLHQISSIVPFLTDSS CCGYHKASYYLAVFYETGLNVPRDQLQGMLYSLVGGQGSERLSSMNLGYKHYQGIDNYPLDWELSYAYYSNIATKTPLDQHTLQGDQAYV ETIRLKDDEILKVQTKEDGDVFMWLKHEATRGNAAAQQRLAQMLFWGQQGVAKNPEAAIEWYAKGALETEDPALIYDYAIVLFKGQGVKK NRRLALELMKKAASKGLHQAVNGLGWYYHKFKKNYAKAAKYWLKAEEMGNPDASYNLGVLHLDGIFPGVPGRNQTLAGEYFHKAAQGGHM EGTLWCSLYYITGNLETFPRDPEKAVVWAKHVAEKNGYLGHVIRKGLNAYLEGSWHEALLYYVLAAETGIEVSQTNLAHICEERPDLARR YLGVNCVWRYYNFSVFQIDAPSFAYLKMGDLYYYGHQNQSQDLELSVQMYAQAALDGDSQFIYVNQSFAPSPDQEVGTLYECFGSDGKLV -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for SEL1L3-ATG12 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for SEL1L3-ATG12 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for SEL1L3-ATG12 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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