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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SERINC5-PALLD (FusionGDB2 ID:80119)

Fusion Gene Summary for SERINC5-PALLD

check button Fusion gene summary
Fusion gene informationFusion gene name: SERINC5-PALLD
Fusion gene ID: 80119
HgeneTgene
Gene symbol

SERINC5

PALLD

Gene ID

256987

23022

Gene nameserine incorporator 5palladin, cytoskeletal associated protein
SynonymsC5orf12|TPO1CGI-151|CGI151|MYN|PNCA1|SIH002
Cytomap

5q14.1

4q32.3

Type of geneprotein-codingprotein-coding
Descriptionserine incorporator 5palladinmyoneurinsarcoma antigen NY-SAR-77
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000507668, ENST00000512972, 
ENST00000509193, ENST00000512721, 
ENST00000513907, 		ENST00000335742, 
ENST00000261509, ENST00000505667, 
ENST00000333488, ENST00000512127, 
ENST00000507735, 
Fusion gene scores* DoF score15 X 10 X 9=135017 X 16 X 5=1360
# samples 1618
** MAII scorelog2(16/1350*10)=-3.07681559705083
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(18/1360*10)=-2.91753783980803
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SERINC5 [Title/Abstract] AND PALLD [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSERINC5(79454659)-PALLD(169847364), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSERINC5

GO:0009597

detection of virus

26416733|26416734

HgeneSERINC5

GO:0045087

innate immune response

26416733|26416734

HgeneSERINC5

GO:0051607

defense response to virus

26416733|26416734


check buttonFusion gene breakpoints across SERINC5 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across PALLD (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-06-0125-02ASERINC5chr5

79454659

-PALLDchr4

169847364

+


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Fusion Gene ORF analysis for SERINC5-PALLD

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000507668ENST00000335742SERINC5chr5

79454659

-PALLDchr4

169847364

+
5CDS-3UTRENST00000507668ENST00000261509SERINC5chr5

79454659

-PALLDchr4

169847364

+
5CDS-3UTRENST00000507668ENST00000505667SERINC5chr5

79454659

-PALLDchr4

169847364

+
5CDS-intronENST00000507668ENST00000333488SERINC5chr5

79454659

-PALLDchr4

169847364

+
5CDS-intronENST00000507668ENST00000512127SERINC5chr5

79454659

-PALLDchr4

169847364

+
5CDS-intronENST00000507668ENST00000507735SERINC5chr5

79454659

-PALLDchr4

169847364

+
In-frameENST00000512972ENST00000335742SERINC5chr5

79454659

-PALLDchr4

169847364

+
5CDS-3UTRENST00000512972ENST00000261509SERINC5chr5

79454659

-PALLDchr4

169847364

+
5CDS-3UTRENST00000512972ENST00000505667SERINC5chr5

79454659

-PALLDchr4

169847364

+
5CDS-intronENST00000512972ENST00000333488SERINC5chr5

79454659

-PALLDchr4

169847364

+
5CDS-intronENST00000512972ENST00000512127SERINC5chr5

79454659

-PALLDchr4

169847364

+
5CDS-intronENST00000512972ENST00000507735SERINC5chr5

79454659

-PALLDchr4

169847364

+
In-frameENST00000509193ENST00000335742SERINC5chr5

79454659

-PALLDchr4

169847364

+
5CDS-3UTRENST00000509193ENST00000261509SERINC5chr5

79454659

-PALLDchr4

169847364

+
5CDS-3UTRENST00000509193ENST00000505667SERINC5chr5

79454659

-PALLDchr4

169847364

+
5CDS-intronENST00000509193ENST00000333488SERINC5chr5

79454659

-PALLDchr4

169847364

+
5CDS-intronENST00000509193ENST00000512127SERINC5chr5

79454659

-PALLDchr4

169847364

+
5CDS-intronENST00000509193ENST00000507735SERINC5chr5

79454659

-PALLDchr4

169847364

+
Frame-shiftENST00000512721ENST00000335742SERINC5chr5

79454659

-PALLDchr4

169847364

+
5CDS-3UTRENST00000512721ENST00000261509SERINC5chr5

79454659

-PALLDchr4

169847364

+
5CDS-3UTRENST00000512721ENST00000505667SERINC5chr5

79454659

-PALLDchr4

169847364

+
5CDS-intronENST00000512721ENST00000333488SERINC5chr5

79454659

-PALLDchr4

169847364

+
5CDS-intronENST00000512721ENST00000512127SERINC5chr5

79454659

-PALLDchr4

169847364

+
5CDS-intronENST00000512721ENST00000507735SERINC5chr5

79454659

-PALLDchr4

169847364

+
intron-3CDSENST00000513907ENST00000335742SERINC5chr5

79454659

-PALLDchr4

169847364

+
intron-3UTRENST00000513907ENST00000261509SERINC5chr5

79454659

-PALLDchr4

169847364

+
intron-3UTRENST00000513907ENST00000505667SERINC5chr5

79454659

-PALLDchr4

169847364

+
intron-intronENST00000513907ENST00000333488SERINC5chr5

79454659

-PALLDchr4

169847364

+
intron-intronENST00000513907ENST00000512127SERINC5chr5

79454659

-PALLDchr4

169847364

+
intron-intronENST00000513907ENST00000507735SERINC5chr5

79454659

-PALLDchr4

169847364

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000507668SERINC5chr579454659-ENST00000335742PALLDchr4169847364+338211371391251370
ENST00000512972SERINC5chr579454659-ENST00000335742PALLDchr4169847364+33281083851197370
ENST00000509193SERINC5chr579454659-ENST00000335742PALLDchr4169847364+33221077851191368

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000507668ENST00000335742SERINC5chr579454659-PALLDchr4169847364+0.000958010.999042
ENST00000512972ENST00000335742SERINC5chr579454659-PALLDchr4169847364+0.0009647880.99903524
ENST00000509193ENST00000335742SERINC5chr579454659-PALLDchr4169847364+0.0007993490.99920064

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Fusion Genomic Features for SERINC5-PALLD


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SERINC5chr579454658-PALLDchr4169847363+0.0043146880.99568534
SERINC5chr579454658-PALLDchr4169847363+0.0043146880.99568534

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SERINC5-PALLD


check button Go to

FGviewer for the breakpoints of chr5:79454659-chr4:169847364

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSERINC5chr5:79454659chr4:169847364ENST00000507668-8135_26328.6666666666667488.3333333333333Compositional biasNote=Cys-rich
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512721-8125_26328.6666666666667462.0Compositional biasNote=Cys-rich
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512972-8145_26328.6666666666667358.3333333333333Compositional biasNote=Cys-rich
HgeneSERINC5chr5:79454659chr4:169847364ENST00000507668-813111_124328.6666666666667488.3333333333333Topological domainExtracellular
HgeneSERINC5chr5:79454659chr4:169847364ENST00000507668-813146_156328.6666666666667488.3333333333333Topological domainCytoplasmic
HgeneSERINC5chr5:79454659chr4:169847364ENST00000507668-813178_198328.6666666666667488.3333333333333Topological domainExtracellular
HgeneSERINC5chr5:79454659chr4:169847364ENST00000507668-8131_36328.6666666666667488.3333333333333Topological domainExtracellular
HgeneSERINC5chr5:79454659chr4:169847364ENST00000507668-813220_230328.6666666666667488.3333333333333Topological domainCytoplasmic
HgeneSERINC5chr5:79454659chr4:169847364ENST00000507668-813252_258328.6666666666667488.3333333333333Topological domainExtracellular
HgeneSERINC5chr5:79454659chr4:169847364ENST00000507668-813280_311328.6666666666667488.3333333333333Topological domainCytoplasmic
HgeneSERINC5chr5:79454659chr4:169847364ENST00000507668-81358_89328.6666666666667488.3333333333333Topological domainCytoplasmic
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512721-812111_124328.6666666666667462.0Topological domainExtracellular
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512721-812146_156328.6666666666667462.0Topological domainCytoplasmic
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512721-812178_198328.6666666666667462.0Topological domainExtracellular
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512721-8121_36328.6666666666667462.0Topological domainExtracellular
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512721-812220_230328.6666666666667462.0Topological domainCytoplasmic
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512721-812252_258328.6666666666667462.0Topological domainExtracellular
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512721-812280_311328.6666666666667462.0Topological domainCytoplasmic
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512721-81258_89328.6666666666667462.0Topological domainCytoplasmic
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512972-814111_124328.6666666666667358.3333333333333Topological domainExtracellular
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512972-814146_156328.6666666666667358.3333333333333Topological domainCytoplasmic
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512972-814178_198328.6666666666667358.3333333333333Topological domainExtracellular
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512972-8141_36328.6666666666667358.3333333333333Topological domainExtracellular
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512972-814220_230328.6666666666667358.3333333333333Topological domainCytoplasmic
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512972-814252_258328.6666666666667358.3333333333333Topological domainExtracellular
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512972-814280_311328.6666666666667358.3333333333333Topological domainCytoplasmic
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512972-81458_89328.6666666666667358.3333333333333Topological domainCytoplasmic
HgeneSERINC5chr5:79454659chr4:169847364ENST00000507668-813125_145328.6666666666667488.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79454659chr4:169847364ENST00000507668-813157_177328.6666666666667488.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79454659chr4:169847364ENST00000507668-813199_219328.6666666666667488.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79454659chr4:169847364ENST00000507668-813231_251328.6666666666667488.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79454659chr4:169847364ENST00000507668-813259_279328.6666666666667488.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79454659chr4:169847364ENST00000507668-81337_57328.6666666666667488.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79454659chr4:169847364ENST00000507668-81390_110328.6666666666667488.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512721-812125_145328.6666666666667462.0TransmembraneHelical
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512721-812157_177328.6666666666667462.0TransmembraneHelical
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512721-812199_219328.6666666666667462.0TransmembraneHelical
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512721-812231_251328.6666666666667462.0TransmembraneHelical
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512721-812259_279328.6666666666667462.0TransmembraneHelical
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512721-81237_57328.6666666666667462.0TransmembraneHelical
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512721-81290_110328.6666666666667462.0TransmembraneHelical
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512972-814125_145328.6666666666667358.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512972-814157_177328.6666666666667358.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512972-814199_219328.6666666666667358.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512972-814231_251328.6666666666667358.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512972-814259_279328.6666666666667358.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512972-81437_57328.6666666666667358.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512972-81490_110328.6666666666667358.3333333333333TransmembraneHelical
TgenePALLDchr5:79454659chr4:169847364ENST000005077351012634_864615.3333333333334673.0Compositional biasNote=Pro-rich
TgenePALLDchr5:79454659chr4:169847364ENST0000026150919211135_12261117.66666666666671812.3333333333333DomainNote=Ig-like C2-type 4
TgenePALLDchr5:79454659chr4:169847364ENST0000026150919211233_13241117.66666666666671812.3333333333333DomainNote=Ig-like C2-type 5
TgenePALLDchr5:79454659chr4:169847364ENST0000033574219211001_1085944.33333333333341002.0DomainNote=Ig-like C2-type 3
TgenePALLDchr5:79454659chr4:169847364ENST0000033574219211135_1226944.33333333333341002.0DomainNote=Ig-like C2-type 4
TgenePALLDchr5:79454659chr4:169847364ENST0000033574219211233_1324944.33333333333341002.0DomainNote=Ig-like C2-type 5
TgenePALLDchr5:79454659chr4:169847364ENST0000050566720221135_12261134.66666666666671113.6666666666667DomainNote=Ig-like C2-type 4
TgenePALLDchr5:79454659chr4:169847364ENST0000050566720221233_13241134.66666666666671113.6666666666667DomainNote=Ig-like C2-type 5
TgenePALLDchr5:79454659chr4:169847364ENST0000050773510121001_1085615.3333333333334673.0DomainNote=Ig-like C2-type 3
TgenePALLDchr5:79454659chr4:169847364ENST0000050773510121135_1226615.3333333333334673.0DomainNote=Ig-like C2-type 4
TgenePALLDchr5:79454659chr4:169847364ENST0000050773510121233_1324615.3333333333334673.0DomainNote=Ig-like C2-type 5
TgenePALLDchr5:79454659chr4:169847364ENST0000051212717191001_1085720.3333333333334778.0DomainNote=Ig-like C2-type 3
TgenePALLDchr5:79454659chr4:169847364ENST0000051212717191135_1226720.3333333333334778.0DomainNote=Ig-like C2-type 4
TgenePALLDchr5:79454659chr4:169847364ENST0000051212717191233_1324720.3333333333334778.0DomainNote=Ig-like C2-type 5

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSERINC5chr5:79454659chr4:169847364ENST00000507668-813333_385328.6666666666667488.3333333333333Topological domainExtracellular
HgeneSERINC5chr5:79454659chr4:169847364ENST00000507668-813407_423328.6666666666667488.3333333333333Topological domainCytoplasmic
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512721-812333_385328.6666666666667462.0Topological domainExtracellular
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512721-812407_423328.6666666666667462.0Topological domainCytoplasmic
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512972-814333_385328.6666666666667358.3333333333333Topological domainExtracellular
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512972-814407_423328.6666666666667358.3333333333333Topological domainCytoplasmic
HgeneSERINC5chr5:79454659chr4:169847364ENST00000507668-813312_332328.6666666666667488.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79454659chr4:169847364ENST00000507668-813386_406328.6666666666667488.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512721-812312_332328.6666666666667462.0TransmembraneHelical
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512721-812386_406328.6666666666667462.0TransmembraneHelical
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512972-814312_332328.6666666666667358.3333333333333TransmembraneHelical
HgeneSERINC5chr5:79454659chr4:169847364ENST00000512972-814386_406328.6666666666667358.3333333333333TransmembraneHelical
TgenePALLDchr5:79454659chr4:169847364ENST000002615091921563_5671117.66666666666671812.3333333333333Compositional biasNote=Poly-Pro
TgenePALLDchr5:79454659chr4:169847364ENST000002615091921634_8641117.66666666666671812.3333333333333Compositional biasNote=Pro-rich
TgenePALLDchr5:79454659chr4:169847364ENST000003357421921563_567944.33333333333341002.0Compositional biasNote=Poly-Pro
TgenePALLDchr5:79454659chr4:169847364ENST000003357421921634_864944.33333333333341002.0Compositional biasNote=Pro-rich
TgenePALLDchr5:79454659chr4:169847364ENST000005056672022563_5671134.66666666666671113.6666666666667Compositional biasNote=Poly-Pro
TgenePALLDchr5:79454659chr4:169847364ENST000005056672022634_8641134.66666666666671113.6666666666667Compositional biasNote=Pro-rich
TgenePALLDchr5:79454659chr4:169847364ENST000005077351012563_567615.3333333333334673.0Compositional biasNote=Poly-Pro
TgenePALLDchr5:79454659chr4:169847364ENST000005121271719563_567720.3333333333334778.0Compositional biasNote=Poly-Pro
TgenePALLDchr5:79454659chr4:169847364ENST000005121271719634_864720.3333333333334778.0Compositional biasNote=Pro-rich
TgenePALLDchr5:79454659chr4:169847364ENST0000026150919211001_10851117.66666666666671812.3333333333333DomainNote=Ig-like C2-type 3
TgenePALLDchr5:79454659chr4:169847364ENST000002615091921271_3601117.66666666666671812.3333333333333DomainNote=Ig-like C2-type 1
TgenePALLDchr5:79454659chr4:169847364ENST000002615091921440_5391117.66666666666671812.3333333333333DomainNote=Ig-like C2-type 2
TgenePALLDchr5:79454659chr4:169847364ENST000003357421921271_360944.33333333333341002.0DomainNote=Ig-like C2-type 1
TgenePALLDchr5:79454659chr4:169847364ENST000003357421921440_539944.33333333333341002.0DomainNote=Ig-like C2-type 2
TgenePALLDchr5:79454659chr4:169847364ENST0000050566720221001_10851134.66666666666671113.6666666666667DomainNote=Ig-like C2-type 3
TgenePALLDchr5:79454659chr4:169847364ENST000005056672022271_3601134.66666666666671113.6666666666667DomainNote=Ig-like C2-type 1
TgenePALLDchr5:79454659chr4:169847364ENST000005056672022440_5391134.66666666666671113.6666666666667DomainNote=Ig-like C2-type 2
TgenePALLDchr5:79454659chr4:169847364ENST000005077351012271_360615.3333333333334673.0DomainNote=Ig-like C2-type 1
TgenePALLDchr5:79454659chr4:169847364ENST000005077351012440_539615.3333333333334673.0DomainNote=Ig-like C2-type 2
TgenePALLDchr5:79454659chr4:169847364ENST000005121271719271_360720.3333333333334778.0DomainNote=Ig-like C2-type 1
TgenePALLDchr5:79454659chr4:169847364ENST000005121271719440_539720.3333333333334778.0DomainNote=Ig-like C2-type 2


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Fusion Gene Sequence for SERINC5-PALLD


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000507668_ENST00000335742_TCGA-06-0125-02A_SERINC5_chr5_79454659_-_PALLD_chr4_169847364_length(transcript)=3382nt_BP=1137nt
ACCCAGGCCTCGGCGCCTAGGCGCTTCGCCGAGGCTGATCTTCGTTCAAGTGTGAGCTGCGGCTGAGCCCAGCGCTCGAGGCGCGAGGCA
GCCAGGAGGGCCCGTGCGGCGCGGGGAGCCAGCGAGCGCGCCTTCGGCATTGGCCGCCGCGATGTCAGCTCAGTGCTGTGCGGGCCAGCT
GGCCTGCTGCTGTGGGTCTGCAGGCTGCTCTCTCTGCTGTGATTGCTGCCCCAGGATTCGGCAGTCCCTCAGCACCCGCTTCATGTACGC
CCTCTACTTCATTCTGGTCGTCGTCCTCTGCTGCATCATGATGTCAACAACCGTGGCTCACAAGATGAAAGAGCACATTCCTTTTTTTGA
AGATATGTGTAAAGGCATTAAAGCTGGTGACACCTGTGAGAAGCTGGTGGGATATTCTGCCGTGTATAGAGTCTGTTTTGGAATGGCTTG
TTTCTTCTTTATCTTCTGTCTACTGACCTTGAAAATCAACAACAGCAAAAGTTGTAGAGCTCATATTCACAATGGCTTTTGGTTCTTTAA
ACTTCTGCTGTTGGGGGCCATGTGCTCAGGAGCTTTCTTCATTCCAGATCAGGACACCTTTCTGAACGCCTGGCGCTATGTGGGAGCCGT
CGGAGGCTTCCTCTTCATTGGCATCCAGCTCCTCCTGCTCGTGGAGTTTGCACATAAGTGGAACAAGAACTGGACAGCAGGCACAGCCAG
TAACAAGCTGTGGTACGCCTCCCTGGCCCTGGTGACGCTCATCATGTATTCCATTGCCACTGGAGGCTTGGTTTTGATGGCAGTGTTTTA
TACACAGAAAGACAGCTGCATGGAAAACAAAATTCTGCTGGGAGTAAATGGAGGCCTGTGCCTGCTTATATCATTGGTAGCCATCTCACC
CTGGGTCCAAAATCGACAGCCACACTCGGGGCTCTTACAATCAGGGGTCATAAGCTGCTATGTCACCTACCTCACCTTCTCAGCTCTGTC
CAGCAAACCTGCAGAAGTAGTTCTAGATGAACATGGGAAAAATGTTACAATCTGTGTGCCTGACTTTGGTCAAGACCTGTACAGAGATGA
AAACTTGGTGACTATACTGGGGACCAGCCTCTTAATCGGATGTATCTTGTATTCATGCCCAGTGGCATCAGCAGTCACAGAGCACCAAGC
CAAAAAAAGTACGGCCCTCAGCCAGTCGCTATGCAGCACTTTCGGACCAGGGACTAGACATCAAAGCAGCGTTCCAACCTGAGGCCAACC
CATCTCACCTGACACTGAATACTGCCTTGGTAGAAAGTGAGGACCTGTAATCCAGCATTCTTGTTAAAGCTGAAACACTGAAACAGCCAT
TGCCTTGACCAACATATTCCTTTGTCACATTATGTAAAAGGCAGAAACATACCTTTGACTATAAGAAATTAAAAAAAAAACACCAAAATA
ATATTTTTCTTACTTGATATACCAAACTTAGTTTAAGTAGATAATGCTAATACAAATATACACATTGCACAGAAAATACACATTTACTGT
CCAATTTAAAACTTTGGAATTGCTGTGATTAAAGTGATCAAAATGCCAAAATACTAAAGGAAATCAATTGTTCACAGGTAACTACAATTT
GTATTATCTACAAGTGCCTTTAAACACAAGATATAGGTGCTGTGTAGCCTGATAGTGTGAAATGTTTAATGAGGGAGTTGTACCACAAAC
AGTACTACAATGATTCTGAAGCACAGTGTATTCAGACAGATACAGTGAACCAAGTGCAATATGTAAGGATGAAAGAAGAAGAGATGACAA
AGAAATCCAAGTAAATGCCTTGTCTTTGCAAATGTTTTTATATTAAATCATAAGGAAGGAACTACTTGCCTTAAATGTTAATATCAAAAG
AGTTTTCTAACAAGGTTAATACCTTAGTTCTTAACATTTTTTTTCTTTATGTGTAGTGTTTTCATGCTACCTTGGTAGGAAACTTATTTA
CAAACCATATTAAAAGGCTAATTTAAATATAAATAATATAAAGTGCTCTGAATAAAGCAGAAATATATTACAGTTCATTCCACAGAAAGC
ATCCAAACCACCCAAATGACCAAGGCATATATAGTATTTGGAGGAATCAGGGGTTTGGAAGGAGTAGGGAGGAGAATGAAGGAAAATGCA
ACCAGCATGATTATAGTGTGTTCATTTAGATAAAAGTAGAAGGCACAGGAGAGGTAGCAAAGGCCAGGCTTTTCTTTGGTTTTCTTCAAA
CATAGGTGAAAAAAACACTGCCATTCACAAGTCAAGGAACCCAGGGCCAGCTGGAAGTGTGGAGCACACATGCTGTGGAGCACACATGCT
GTGGAGATTGCAGTGTGTCTGAGGTTTGTGTAGTAGTGGAAGATTTTAGGTATGTAGAGCAAGTTGAAAATGGATTGAGACTGCATGGTG
GCATAAATGAGAAATTGCCTGTAGCATCTAGTCTACTTGAAGGAAGTGGAGACATAAGGAGAGACAAAAACAGGTTTGTGCCATAAAGTA
TTTTTTCAAAGACACCAAGATGTGGTAAATGAAAATTATTAGTTCACTTCCCTGCTGCCATGAAACTTTGCCTTAAGAAGGTGCTGGATT
CCAAGGTTTGTAAAGGCATCTCGGTAAAGACTGCTTTTTGAATGCATATGATTTTGCATCAGCTAGACTGAGTTGATTCTGACCAGACTT
GATGGTTTTAAGTCGGAACCGATAAATTTTAAAAAGGAGAAAAAATAATTTGACCTAGTAGTATAAAACATGAGGCTTTAATGGTACTTT
GCTATGAAAAGAAAACACTGTATTCCTTATGCAAAACACATGTATCTTTCATTATTTATAAGTGGCCTCTCTTAGCTCAGTTACTCAATT
CATACGTAGTATTTTTTAAAATAATTTTATATCTGTGTACCACCCCATATATTTCATATTACTGTTTCACATGTACAGCTTTCTACTTCT
TTGTAAGAACACCAACCAACCAAGGTTTAAGTGATTAATAGGCTTGAGCACCGGGTGGCAGATGTTCTATGCAGTGTGGTTCAAGTTTCT
TTGACCGCACTTATATGCATTGCTAATATGGAATTTAAGATACCATACACAGTCTCTCATGGACCTATCTCTATTGTAGAATTATGACTT
ATGTCTTACTTGCCAAATTTTTCTGAATGTGACCTTTTTTTGCTGATTTGCTGGGTTTGGGATTAACTAGCATTATTTTGCCACCTTTAT
ATTGTATTTATAAAAAAAAAAGTACTATCAATCAATCATACTACTTTGGATTGTTGTGCTGGTGTAATGTGGATTTAACATCAATAAATA

>In-frame_ENST00000507668_ENST00000335742_TCGA-06-0125-02A_SERINC5_chr5_79454659_-_PALLD_chr4_169847364_length(amino acids)=370AA_start in transcript=139_stop in transcript=1251
MAAAMSAQCCAGQLACCCGSAGCSLCCDCCPRIRQSLSTRFMYALYFILVVVLCCIMMSTTVAHKMKEHIPFFEDMCKGIKAGDTCEKLV
GYSAVYRVCFGMACFFFIFCLLTLKINNSKSCRAHIHNGFWFFKLLLLGAMCSGAFFIPDQDTFLNAWRYVGAVGGFLFIGIQLLLLVEF
AHKWNKNWTAGTASNKLWYASLALVTLIMYSIATGGLVLMAVFYTQKDSCMENKILLGVNGGLCLLISLVAISPWVQNRQPHSGLLQSGV
ISCYVTYLTFSALSSKPAEVVLDEHGKNVTICVPDFGQDLYRDENLVTILGTSLLIGCILYSCPVASAVTEHQAKKSTALSQSLCSTFGP

--------------------------------------------------------------
>In-frame_ENST00000512972_ENST00000335742_TCGA-06-0125-02A_SERINC5_chr5_79454659_-_PALLD_chr4_169847364_length(transcript)=3328nt_BP=1083nt
AGCTGCGGCTGAGCCCAGCGCTCGAGGCGCGAGGCAGCCAGGAGGGCCCGTGCGGCGCGGGGAGCCAGCGAGCGCGCCTTCGGCATTGGC
CGCCGCGATGTCAGCTCAGTGCTGTGCGGGCCAGCTGGCCTGCTGCTGTGGGTCTGCAGGCTGCTCTCTCTGCTGTGATTGCTGCCCCAG
GATTCGGCAGTCCCTCAGCACCCGCTTCATGTACGCCCTCTACTTCATTCTGGTCGTCGTCCTCTGCTGCATCATGATGTCAACAACCGT
GGCTCACAAGATGAAAGAGCACATTCCTTTTTTTGAAGATATGTGTAAAGGCATTAAAGCTGGTGACACCTGTGAGAAGCTGGTGGGATA
TTCTGCCGTGTATAGAGTCTGTTTTGGAATGGCTTGTTTCTTCTTTATCTTCTGTCTACTGACCTTGAAAATCAACAACAGCAAAAGTTG
TAGAGCTCATATTCACAATGGCTTTTGGTTCTTTAAACTTCTGCTGTTGGGGGCCATGTGCTCAGGAGCTTTCTTCATTCCAGATCAGGA
CACCTTTCTGAACGCCTGGCGCTATGTGGGAGCCGTCGGAGGCTTCCTCTTCATTGGCATCCAGCTCCTCCTGCTCGTGGAGTTTGCACA
TAAGTGGAACAAGAACTGGACAGCAGGCACAGCCAGTAACAAGCTGTGGTACGCCTCCCTGGCCCTGGTGACGCTCATCATGTATTCCAT
TGCCACTGGAGGCTTGGTTTTGATGGCAGTGTTTTATACACAGAAAGACAGCTGCATGGAAAACAAAATTCTGCTGGGAGTAAATGGAGG
CCTGTGCCTGCTTATATCATTGGTAGCCATCTCACCCTGGGTCCAAAATCGACAGCCACACTCGGGGCTCTTACAATCAGGGGTCATAAG
CTGCTATGTCACCTACCTCACCTTCTCAGCTCTGTCCAGCAAACCTGCAGAAGTAGTTCTAGATGAACATGGGAAAAATGTTACAATCTG
TGTGCCTGACTTTGGTCAAGACCTGTACAGAGATGAAAACTTGGTGACTATACTGGGGACCAGCCTCTTAATCGGATGTATCTTGTATTC
ATGCCCAGTGGCATCAGCAGTCACAGAGCACCAAGCCAAAAAAAGTACGGCCCTCAGCCAGTCGCTATGCAGCACTTTCGGACCAGGGAC
TAGACATCAAAGCAGCGTTCCAACCTGAGGCCAACCCATCTCACCTGACACTGAATACTGCCTTGGTAGAAAGTGAGGACCTGTAATCCA
GCATTCTTGTTAAAGCTGAAACACTGAAACAGCCATTGCCTTGACCAACATATTCCTTTGTCACATTATGTAAAAGGCAGAAACATACCT
TTGACTATAAGAAATTAAAAAAAAAACACCAAAATAATATTTTTCTTACTTGATATACCAAACTTAGTTTAAGTAGATAATGCTAATACA
AATATACACATTGCACAGAAAATACACATTTACTGTCCAATTTAAAACTTTGGAATTGCTGTGATTAAAGTGATCAAAATGCCAAAATAC
TAAAGGAAATCAATTGTTCACAGGTAACTACAATTTGTATTATCTACAAGTGCCTTTAAACACAAGATATAGGTGCTGTGTAGCCTGATA
GTGTGAAATGTTTAATGAGGGAGTTGTACCACAAACAGTACTACAATGATTCTGAAGCACAGTGTATTCAGACAGATACAGTGAACCAAG
TGCAATATGTAAGGATGAAAGAAGAAGAGATGACAAAGAAATCCAAGTAAATGCCTTGTCTTTGCAAATGTTTTTATATTAAATCATAAG
GAAGGAACTACTTGCCTTAAATGTTAATATCAAAAGAGTTTTCTAACAAGGTTAATACCTTAGTTCTTAACATTTTTTTTCTTTATGTGT
AGTGTTTTCATGCTACCTTGGTAGGAAACTTATTTACAAACCATATTAAAAGGCTAATTTAAATATAAATAATATAAAGTGCTCTGAATA
AAGCAGAAATATATTACAGTTCATTCCACAGAAAGCATCCAAACCACCCAAATGACCAAGGCATATATAGTATTTGGAGGAATCAGGGGT
TTGGAAGGAGTAGGGAGGAGAATGAAGGAAAATGCAACCAGCATGATTATAGTGTGTTCATTTAGATAAAAGTAGAAGGCACAGGAGAGG
TAGCAAAGGCCAGGCTTTTCTTTGGTTTTCTTCAAACATAGGTGAAAAAAACACTGCCATTCACAAGTCAAGGAACCCAGGGCCAGCTGG
AAGTGTGGAGCACACATGCTGTGGAGCACACATGCTGTGGAGATTGCAGTGTGTCTGAGGTTTGTGTAGTAGTGGAAGATTTTAGGTATG
TAGAGCAAGTTGAAAATGGATTGAGACTGCATGGTGGCATAAATGAGAAATTGCCTGTAGCATCTAGTCTACTTGAAGGAAGTGGAGACA
TAAGGAGAGACAAAAACAGGTTTGTGCCATAAAGTATTTTTTCAAAGACACCAAGATGTGGTAAATGAAAATTATTAGTTCACTTCCCTG
CTGCCATGAAACTTTGCCTTAAGAAGGTGCTGGATTCCAAGGTTTGTAAAGGCATCTCGGTAAAGACTGCTTTTTGAATGCATATGATTT
TGCATCAGCTAGACTGAGTTGATTCTGACCAGACTTGATGGTTTTAAGTCGGAACCGATAAATTTTAAAAAGGAGAAAAAATAATTTGAC
CTAGTAGTATAAAACATGAGGCTTTAATGGTACTTTGCTATGAAAAGAAAACACTGTATTCCTTATGCAAAACACATGTATCTTTCATTA
TTTATAAGTGGCCTCTCTTAGCTCAGTTACTCAATTCATACGTAGTATTTTTTAAAATAATTTTATATCTGTGTACCACCCCATATATTT
CATATTACTGTTTCACATGTACAGCTTTCTACTTCTTTGTAAGAACACCAACCAACCAAGGTTTAAGTGATTAATAGGCTTGAGCACCGG
GTGGCAGATGTTCTATGCAGTGTGGTTCAAGTTTCTTTGACCGCACTTATATGCATTGCTAATATGGAATTTAAGATACCATACACAGTC
TCTCATGGACCTATCTCTATTGTAGAATTATGACTTATGTCTTACTTGCCAAATTTTTCTGAATGTGACCTTTTTTTGCTGATTTGCTGG
GTTTGGGATTAACTAGCATTATTTTGCCACCTTTATATTGTATTTATAAAAAAAAAAGTACTATCAATCAATCATACTACTTTGGATTGT

>In-frame_ENST00000512972_ENST00000335742_TCGA-06-0125-02A_SERINC5_chr5_79454659_-_PALLD_chr4_169847364_length(amino acids)=370AA_start in transcript=85_stop in transcript=1197
MAAAMSAQCCAGQLACCCGSAGCSLCCDCCPRIRQSLSTRFMYALYFILVVVLCCIMMSTTVAHKMKEHIPFFEDMCKGIKAGDTCEKLV
GYSAVYRVCFGMACFFFIFCLLTLKINNSKSCRAHIHNGFWFFKLLLLGAMCSGAFFIPDQDTFLNAWRYVGAVGGFLFIGIQLLLLVEF
AHKWNKNWTAGTASNKLWYASLALVTLIMYSIATGGLVLMAVFYTQKDSCMENKILLGVNGGLCLLISLVAISPWVQNRQPHSGLLQSGV
ISCYVTYLTFSALSSKPAEVVLDEHGKNVTICVPDFGQDLYRDENLVTILGTSLLIGCILYSCPVASAVTEHQAKKSTALSQSLCSTFGP

--------------------------------------------------------------
>In-frame_ENST00000509193_ENST00000335742_TCGA-06-0125-02A_SERINC5_chr5_79454659_-_PALLD_chr4_169847364_length(transcript)=3322nt_BP=1077nt
AGCTGCGGCTGAGCCCAGCGCTCGAGGCGCGAGGCAGCCAGGAGGGCCCGTGCGGCGCGGGGAGCCAGCGAGCGCGCCTTCGGCATTGGC
CGCCGCGATGTCAGCTCAGTGCTGTGCGGGCCAGCTGGCCTGCTGCTGTGGGTCTGCAGGCTGCTCTCTCTGCTGTGATTGCTGCCCCAG
GATTCGGCAGTCCCTCAGCACCCGCTTCATGTACGCCCTCTACTTCATTCTGGTCGTCGTCCTCTGCTGCATCATGATGTCAACAACCGT
GGCTCACAAGATGAAAGAGCACATTCCTTTTTTTGAAGATATGTGTAAAGGCATTAAAGCTGGTGACACCTGTGAGAAGCTGGTGGGATA
TTCTGCCGTGTATAGAGTCTGTTTTGGAATGGCTTGTTTCTTCTTTATCTTCTGTCTACTGACCTTGAAAATCAACAACAGCAAAAGTTG
TAGAGCTCATATTCACAATGGCTTTTGGTTCTTTAAACTTCTGCTGTTGGGGGCCATGTGCTCAGGAGCTTTCTTCATTCCAGATCAGGA
CACCTTTCTGAACGCCTGGCGCTATGTGGGAGCCGTCGGAGGCTTCCTCTTCATTGGCATCCAGCTCCTCCTGCTCGTGGAGTTTGCACA
TAAGTGGAACAAGAACTGGACAGCAGGCACAGCCAGTAACAAGCTGTGGTACGCCTCCCTGGCCCTGGTGACGCTCATCATGTATTCCAT
TGCCACTGGAGGCTTGGTTTTGATGGCAGTGTTTTATACACAGAAAGACAGCTGCATGGAAAACAAAATTCTGCTGGGAGTAAATGGAGG
CCTGTGCCTGCTTATATCATTGGTAGCCATCTCACCCTGGGTCCAAAATCGACAGCCACACTCGGGGCTCTTACAATCAGGGGTCATAAG
CTGCTATGTCACCTACCTCACCTTCTCAGCTCTGTCCAGCAAACCTGCAGAAGTAGATGAACATGGGAAAAATGTTACAATCTGTGTGCC
TGACTTTGGTCAAGACCTGTACAGAGATGAAAACTTGGTGACTATACTGGGGACCAGCCTCTTAATCGGATGTATCTTGTATTCATGCCC
AGTGGCATCAGCAGTCACAGAGCACCAAGCCAAAAAAAGTACGGCCCTCAGCCAGTCGCTATGCAGCACTTTCGGACCAGGGACTAGACA
TCAAAGCAGCGTTCCAACCTGAGGCCAACCCATCTCACCTGACACTGAATACTGCCTTGGTAGAAAGTGAGGACCTGTAATCCAGCATTC
TTGTTAAAGCTGAAACACTGAAACAGCCATTGCCTTGACCAACATATTCCTTTGTCACATTATGTAAAAGGCAGAAACATACCTTTGACT
ATAAGAAATTAAAAAAAAAACACCAAAATAATATTTTTCTTACTTGATATACCAAACTTAGTTTAAGTAGATAATGCTAATACAAATATA
CACATTGCACAGAAAATACACATTTACTGTCCAATTTAAAACTTTGGAATTGCTGTGATTAAAGTGATCAAAATGCCAAAATACTAAAGG
AAATCAATTGTTCACAGGTAACTACAATTTGTATTATCTACAAGTGCCTTTAAACACAAGATATAGGTGCTGTGTAGCCTGATAGTGTGA
AATGTTTAATGAGGGAGTTGTACCACAAACAGTACTACAATGATTCTGAAGCACAGTGTATTCAGACAGATACAGTGAACCAAGTGCAAT
ATGTAAGGATGAAAGAAGAAGAGATGACAAAGAAATCCAAGTAAATGCCTTGTCTTTGCAAATGTTTTTATATTAAATCATAAGGAAGGA
ACTACTTGCCTTAAATGTTAATATCAAAAGAGTTTTCTAACAAGGTTAATACCTTAGTTCTTAACATTTTTTTTCTTTATGTGTAGTGTT
TTCATGCTACCTTGGTAGGAAACTTATTTACAAACCATATTAAAAGGCTAATTTAAATATAAATAATATAAAGTGCTCTGAATAAAGCAG
AAATATATTACAGTTCATTCCACAGAAAGCATCCAAACCACCCAAATGACCAAGGCATATATAGTATTTGGAGGAATCAGGGGTTTGGAA
GGAGTAGGGAGGAGAATGAAGGAAAATGCAACCAGCATGATTATAGTGTGTTCATTTAGATAAAAGTAGAAGGCACAGGAGAGGTAGCAA
AGGCCAGGCTTTTCTTTGGTTTTCTTCAAACATAGGTGAAAAAAACACTGCCATTCACAAGTCAAGGAACCCAGGGCCAGCTGGAAGTGT
GGAGCACACATGCTGTGGAGCACACATGCTGTGGAGATTGCAGTGTGTCTGAGGTTTGTGTAGTAGTGGAAGATTTTAGGTATGTAGAGC
AAGTTGAAAATGGATTGAGACTGCATGGTGGCATAAATGAGAAATTGCCTGTAGCATCTAGTCTACTTGAAGGAAGTGGAGACATAAGGA
GAGACAAAAACAGGTTTGTGCCATAAAGTATTTTTTCAAAGACACCAAGATGTGGTAAATGAAAATTATTAGTTCACTTCCCTGCTGCCA
TGAAACTTTGCCTTAAGAAGGTGCTGGATTCCAAGGTTTGTAAAGGCATCTCGGTAAAGACTGCTTTTTGAATGCATATGATTTTGCATC
AGCTAGACTGAGTTGATTCTGACCAGACTTGATGGTTTTAAGTCGGAACCGATAAATTTTAAAAAGGAGAAAAAATAATTTGACCTAGTA
GTATAAAACATGAGGCTTTAATGGTACTTTGCTATGAAAAGAAAACACTGTATTCCTTATGCAAAACACATGTATCTTTCATTATTTATA
AGTGGCCTCTCTTAGCTCAGTTACTCAATTCATACGTAGTATTTTTTAAAATAATTTTATATCTGTGTACCACCCCATATATTTCATATT
ACTGTTTCACATGTACAGCTTTCTACTTCTTTGTAAGAACACCAACCAACCAAGGTTTAAGTGATTAATAGGCTTGAGCACCGGGTGGCA
GATGTTCTATGCAGTGTGGTTCAAGTTTCTTTGACCGCACTTATATGCATTGCTAATATGGAATTTAAGATACCATACACAGTCTCTCAT
GGACCTATCTCTATTGTAGAATTATGACTTATGTCTTACTTGCCAAATTTTTCTGAATGTGACCTTTTTTTGCTGATTTGCTGGGTTTGG
GATTAACTAGCATTATTTTGCCACCTTTATATTGTATTTATAAAAAAAAAAGTACTATCAATCAATCATACTACTTTGGATTGTTGTGCT

>In-frame_ENST00000509193_ENST00000335742_TCGA-06-0125-02A_SERINC5_chr5_79454659_-_PALLD_chr4_169847364_length(amino acids)=368AA_start in transcript=85_stop in transcript=1191
MAAAMSAQCCAGQLACCCGSAGCSLCCDCCPRIRQSLSTRFMYALYFILVVVLCCIMMSTTVAHKMKEHIPFFEDMCKGIKAGDTCEKLV
GYSAVYRVCFGMACFFFIFCLLTLKINNSKSCRAHIHNGFWFFKLLLLGAMCSGAFFIPDQDTFLNAWRYVGAVGGFLFIGIQLLLLVEF
AHKWNKNWTAGTASNKLWYASLALVTLIMYSIATGGLVLMAVFYTQKDSCMENKILLGVNGGLCLLISLVAISPWVQNRQPHSGLLQSGV
ISCYVTYLTFSALSSKPAEVDEHGKNVTICVPDFGQDLYRDENLVTILGTSLLIGCILYSCPVASAVTEHQAKKSTALSQSLCSTFGPGT

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Fusion Gene PPI Analysis for SERINC5-PALLD


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgenePALLDchr5:79454659chr4:169847364ENST000005077351012833_890615.3333333333334673.0ACTN
TgenePALLDchr5:79454659chr4:169847364ENST000005121271719833_890720.3333333333334778.0ACTN
TgenePALLDchr5:79454659chr4:169847364ENST000005077351012766_831615.3333333333334673.0EPS8
TgenePALLDchr5:79454659chr4:169847364ENST000005121271719766_831720.3333333333334778.0EPS8
TgenePALLDchr5:79454659chr4:169847364ENST0000026150919211137_12261117.66666666666671812.3333333333333EZR
TgenePALLDchr5:79454659chr4:169847364ENST0000026150919211236_13261117.66666666666671812.3333333333333EZR
TgenePALLDchr5:79454659chr4:169847364ENST0000033574219211137_1226944.33333333333341002.0EZR
TgenePALLDchr5:79454659chr4:169847364ENST0000033574219211236_1326944.33333333333341002.0EZR
TgenePALLDchr5:79454659chr4:169847364ENST0000050566720221137_12261134.66666666666671113.6666666666667EZR
TgenePALLDchr5:79454659chr4:169847364ENST0000050566720221236_13261134.66666666666671113.6666666666667EZR
TgenePALLDchr5:79454659chr4:169847364ENST0000050773510121137_1226615.3333333333334673.0EZR
TgenePALLDchr5:79454659chr4:169847364ENST0000050773510121236_1326615.3333333333334673.0EZR
TgenePALLDchr5:79454659chr4:169847364ENST0000051212717191137_1226720.3333333333334778.0EZR
TgenePALLDchr5:79454659chr4:169847364ENST0000051212717191236_1326720.3333333333334778.0EZR
TgenePALLDchr5:79454659chr4:169847364ENST000005077351012646_676615.3333333333334673.0LASP1
TgenePALLDchr5:79454659chr4:169847364ENST000005077351012676_696615.3333333333334673.0SORBS2%2C SPIN90 and SRC
TgenePALLDchr5:79454659chr4:169847364ENST000005077351012796_831615.3333333333334673.0SORBS2%2C SPIN90%2C SRC and PFN1
TgenePALLDchr5:79454659chr4:169847364ENST000005121271719796_831720.3333333333334778.0SORBS2%2C SPIN90%2C SRC and PFN1
TgenePALLDchr5:79454659chr4:169847364ENST000005077351012819_823615.3333333333334673.0VASP
TgenePALLDchr5:79454659chr4:169847364ENST000005121271719819_823720.3333333333334778.0VASP


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgenePALLDchr5:79454659chr4:169847364ENST000002615091921833_8901117.66666666666671812.3333333333333ACTN
TgenePALLDchr5:79454659chr4:169847364ENST000003357421921833_890944.33333333333341002.0ACTN
TgenePALLDchr5:79454659chr4:169847364ENST000005056672022833_8901134.66666666666671113.6666666666667ACTN
TgenePALLDchr5:79454659chr4:169847364ENST000002615091921766_8311117.66666666666671812.3333333333333EPS8
TgenePALLDchr5:79454659chr4:169847364ENST000003357421921766_831944.33333333333341002.0EPS8
TgenePALLDchr5:79454659chr4:169847364ENST000005056672022766_8311134.66666666666671113.6666666666667EPS8
TgenePALLDchr5:79454659chr4:169847364ENST000002615091921646_6761117.66666666666671812.3333333333333LASP1
TgenePALLDchr5:79454659chr4:169847364ENST000003357421921646_676944.33333333333341002.0LASP1
TgenePALLDchr5:79454659chr4:169847364ENST000005056672022646_6761134.66666666666671113.6666666666667LASP1
TgenePALLDchr5:79454659chr4:169847364ENST000005121271719646_676720.3333333333334778.0LASP1
TgenePALLDchr5:79454659chr4:169847364ENST000002615091921676_6961117.66666666666671812.3333333333333SORBS2%2C SPIN90 and SRC
TgenePALLDchr5:79454659chr4:169847364ENST000003357421921676_696944.33333333333341002.0SORBS2%2C SPIN90 and SRC
TgenePALLDchr5:79454659chr4:169847364ENST000005056672022676_6961134.66666666666671113.6666666666667SORBS2%2C SPIN90 and SRC
TgenePALLDchr5:79454659chr4:169847364ENST000005121271719676_696720.3333333333334778.0SORBS2%2C SPIN90 and SRC
TgenePALLDchr5:79454659chr4:169847364ENST000002615091921796_8311117.66666666666671812.3333333333333SORBS2%2C SPIN90%2C SRC and PFN1
TgenePALLDchr5:79454659chr4:169847364ENST000003357421921796_831944.33333333333341002.0SORBS2%2C SPIN90%2C SRC and PFN1
TgenePALLDchr5:79454659chr4:169847364ENST000005056672022796_8311134.66666666666671113.6666666666667SORBS2%2C SPIN90%2C SRC and PFN1
TgenePALLDchr5:79454659chr4:169847364ENST000002615091921562_5661117.66666666666671812.3333333333333VASP
TgenePALLDchr5:79454659chr4:169847364ENST000002615091921819_8231117.66666666666671812.3333333333333VASP
TgenePALLDchr5:79454659chr4:169847364ENST000003357421921562_566944.33333333333341002.0VASP
TgenePALLDchr5:79454659chr4:169847364ENST000003357421921819_823944.33333333333341002.0VASP
TgenePALLDchr5:79454659chr4:169847364ENST000005056672022562_5661134.66666666666671113.6666666666667VASP
TgenePALLDchr5:79454659chr4:169847364ENST000005056672022819_8231134.66666666666671113.6666666666667VASP
TgenePALLDchr5:79454659chr4:169847364ENST000005077351012562_566615.3333333333334673.0VASP
TgenePALLDchr5:79454659chr4:169847364ENST000005121271719562_566720.3333333333334778.0VASP


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SERINC5-PALLD


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SERINC5-PALLD


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgenePALLDC0043094Weight Gain1CTD_human
TgenePALLDC2931038Pancreatic carcinoma, familial1ORPHANET