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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SERPINA1-FGG (FusionGDB2 ID:80146)

Fusion Gene Summary for SERPINA1-FGG

check button Fusion gene summary
Fusion gene informationFusion gene name: SERPINA1-FGG
Fusion gene ID: 80146
HgeneTgene
Gene symbol

SERPINA1

FGG

Gene ID

5265

2266

Gene nameserpin family A member 1fibrinogen gamma chain
SynonymsA1A|A1AT|AAT|PI|PI1|PRO2275|alpha1AT|nNIF-
Cytomap

14q32.13

4q32.1

Type of geneprotein-codingprotein-coding
Descriptionalpha-1-antitrypsinalpha-1 antitrypsinalpha-1 protease inhibitoralpha-1-antiproteinasealpha-1-antitrypsin nullalpha-1-antitrypsin short transcript variant 1C4alpha-1-antitrypsin short transcript variant 1C5epididymis secretory sperm binding proteinfibrinogen gamma chainfibrinogen, gamma polypeptidetesticular tissue protein Li 70
Modification date2020032720200329
UniProtAcc.

Q96C11

Ensembl transtripts involved in fusion geneENST00000440909, ENST00000448921, 
ENST00000437397, ENST00000355814, 
ENST00000393087, ENST00000393088, 
ENST00000404814, ENST00000449399, 
ENST00000402629, ENST00000555289, 
ENST00000404648, ENST00000405164, 
ENST00000336098, ENST00000407946, 
Fusion gene scores* DoF score28 X 24 X 6=40329 X 11 X 4=396
# samples 2811
** MAII scorelog2(28/4032*10)=-3.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/396*10)=-1.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SERPINA1 [Title/Abstract] AND FGG [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSERPINA1(94847208)-FGG(155526218), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneFGG

GO:0007160

cell-matrix adhesion

10903502

TgeneFGG

GO:0031639

plasminogen activation

16846481

TgeneFGG

GO:0034116

positive regulation of heterotypic cell-cell adhesion

8100742

TgeneFGG

GO:0034622

cellular protein-containing complex assembly

8910396

TgeneFGG

GO:0042730

fibrinolysis

16846481

TgeneFGG

GO:0045907

positive regulation of vasoconstriction

15739255

TgeneFGG

GO:0045921

positive regulation of exocytosis

19193866

TgeneFGG

GO:0050714

positive regulation of protein secretion

19193866

TgeneFGG

GO:0051592

response to calcium ion

6777381

TgeneFGG

GO:0070374

positive regulation of ERK1 and ERK2 cascade

10903502|19193866

TgeneFGG

GO:0070527

platelet aggregation

6281794

TgeneFGG

GO:0072378

blood coagulation, fibrin clot formation

16846481

TgeneFGG

GO:0090277

positive regulation of peptide hormone secretion

19193866

TgeneFGG

GO:1902042

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

10903502

TgeneFGG

GO:2000352

negative regulation of endothelial cell apoptotic process

10903502


check buttonFusion gene breakpoints across SERPINA1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across FGG (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LIHCTCGA-FV-A23B-01ASERPINA1chr14

94847208

-FGGchr4

155526218

-


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Fusion Gene ORF analysis for SERPINA1-FGG

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000440909ENST00000404648SERPINA1chr14

94847208

-FGGchr4

155526218

-
Frame-shiftENST00000440909ENST00000405164SERPINA1chr14

94847208

-FGGchr4

155526218

-
Frame-shiftENST00000440909ENST00000336098SERPINA1chr14

94847208

-FGGchr4

155526218

-
Frame-shiftENST00000440909ENST00000407946SERPINA1chr14

94847208

-FGGchr4

155526218

-
Frame-shiftENST00000448921ENST00000404648SERPINA1chr14

94847208

-FGGchr4

155526218

-
Frame-shiftENST00000448921ENST00000405164SERPINA1chr14

94847208

-FGGchr4

155526218

-
Frame-shiftENST00000448921ENST00000336098SERPINA1chr14

94847208

-FGGchr4

155526218

-
Frame-shiftENST00000448921ENST00000407946SERPINA1chr14

94847208

-FGGchr4

155526218

-
Frame-shiftENST00000437397ENST00000404648SERPINA1chr14

94847208

-FGGchr4

155526218

-
Frame-shiftENST00000437397ENST00000405164SERPINA1chr14

94847208

-FGGchr4

155526218

-
Frame-shiftENST00000437397ENST00000336098SERPINA1chr14

94847208

-FGGchr4

155526218

-
Frame-shiftENST00000437397ENST00000407946SERPINA1chr14

94847208

-FGGchr4

155526218

-
Frame-shiftENST00000355814ENST00000404648SERPINA1chr14

94847208

-FGGchr4

155526218

-
Frame-shiftENST00000355814ENST00000405164SERPINA1chr14

94847208

-FGGchr4

155526218

-
In-frameENST00000355814ENST00000336098SERPINA1chr14

94847208

-FGGchr4

155526218

-
Frame-shiftENST00000355814ENST00000407946SERPINA1chr14

94847208

-FGGchr4

155526218

-
Frame-shiftENST00000393087ENST00000404648SERPINA1chr14

94847208

-FGGchr4

155526218

-
Frame-shiftENST00000393087ENST00000405164SERPINA1chr14

94847208

-FGGchr4

155526218

-
In-frameENST00000393087ENST00000336098SERPINA1chr14

94847208

-FGGchr4

155526218

-
Frame-shiftENST00000393087ENST00000407946SERPINA1chr14

94847208

-FGGchr4

155526218

-
In-frameENST00000393088ENST00000404648SERPINA1chr14

94847208

-FGGchr4

155526218

-
In-frameENST00000393088ENST00000405164SERPINA1chr14

94847208

-FGGchr4

155526218

-
Frame-shiftENST00000393088ENST00000336098SERPINA1chr14

94847208

-FGGchr4

155526218

-
In-frameENST00000393088ENST00000407946SERPINA1chr14

94847208

-FGGchr4

155526218

-
In-frameENST00000404814ENST00000404648SERPINA1chr14

94847208

-FGGchr4

155526218

-
In-frameENST00000404814ENST00000405164SERPINA1chr14

94847208

-FGGchr4

155526218

-
Frame-shiftENST00000404814ENST00000336098SERPINA1chr14

94847208

-FGGchr4

155526218

-
In-frameENST00000404814ENST00000407946SERPINA1chr14

94847208

-FGGchr4

155526218

-
In-frameENST00000449399ENST00000404648SERPINA1chr14

94847208

-FGGchr4

155526218

-
In-frameENST00000449399ENST00000405164SERPINA1chr14

94847208

-FGGchr4

155526218

-
Frame-shiftENST00000449399ENST00000336098SERPINA1chr14

94847208

-FGGchr4

155526218

-
In-frameENST00000449399ENST00000407946SERPINA1chr14

94847208

-FGGchr4

155526218

-
Frame-shiftENST00000402629ENST00000404648SERPINA1chr14

94847208

-FGGchr4

155526218

-
Frame-shiftENST00000402629ENST00000405164SERPINA1chr14

94847208

-FGGchr4

155526218

-
In-frameENST00000402629ENST00000336098SERPINA1chr14

94847208

-FGGchr4

155526218

-
Frame-shiftENST00000402629ENST00000407946SERPINA1chr14

94847208

-FGGchr4

155526218

-
intron-3CDSENST00000555289ENST00000404648SERPINA1chr14

94847208

-FGGchr4

155526218

-
intron-3CDSENST00000555289ENST00000405164SERPINA1chr14

94847208

-FGGchr4

155526218

-
intron-3CDSENST00000555289ENST00000336098SERPINA1chr14

94847208

-FGGchr4

155526218

-
intron-3CDSENST00000555289ENST00000407946SERPINA1chr14

94847208

-FGGchr4

155526218

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000355814SERPINA1chr1494847208-ENST00000336098FGGchr4155526218-168511942441224326
ENST00000393087SERPINA1chr1494847208-ENST00000336098FGGchr4155526218-167311821091212367
ENST00000393088SERPINA1chr1494847208-ENST00000404648FGGchr4155526218-186314724591502347
ENST00000393088SERPINA1chr1494847208-ENST00000405164FGGchr4155526218-182414724591502347
ENST00000393088SERPINA1chr1494847208-ENST00000407946FGGchr4155526218-192914724591502347
ENST00000404814SERPINA1chr1494847208-ENST00000404648FGGchr4155526218-1619122851258417
ENST00000404814SERPINA1chr1494847208-ENST00000405164FGGchr4155526218-1580122851258417
ENST00000404814SERPINA1chr1494847208-ENST00000407946FGGchr4155526218-1685122851258417
ENST00000449399SERPINA1chr1494847208-ENST00000404648FGGchr4155526218-16101219261249407
ENST00000449399SERPINA1chr1494847208-ENST00000405164FGGchr4155526218-15711219261249407
ENST00000449399SERPINA1chr1494847208-ENST00000407946FGGchr4155526218-16761219261249407
ENST00000402629SERPINA1chr1494847208-ENST00000336098FGGchr4155526218-144295110981323

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000355814ENST00000336098SERPINA1chr1494847208-FGGchr4155526218-0.0014899470.99851006
ENST00000393087ENST00000336098SERPINA1chr1494847208-FGGchr4155526218-0.0014645310.9985355
ENST00000393088ENST00000404648SERPINA1chr1494847208-FGGchr4155526218-0.0022448860.9977551
ENST00000393088ENST00000405164SERPINA1chr1494847208-FGGchr4155526218-0.0023336810.99766636
ENST00000393088ENST00000407946SERPINA1chr1494847208-FGGchr4155526218-0.0022443930.9977556
ENST00000404814ENST00000404648SERPINA1chr1494847208-FGGchr4155526218-0.0021063030.99789375
ENST00000404814ENST00000405164SERPINA1chr1494847208-FGGchr4155526218-0.0022607010.9977393
ENST00000404814ENST00000407946SERPINA1chr1494847208-FGGchr4155526218-0.0020325740.9979674
ENST00000449399ENST00000404648SERPINA1chr1494847208-FGGchr4155526218-0.0023026480.9976973
ENST00000449399ENST00000405164SERPINA1chr1494847208-FGGchr4155526218-0.0024594860.9975405
ENST00000449399ENST00000407946SERPINA1chr1494847208-FGGchr4155526218-0.0020943350.99790573
ENST00000402629ENST00000336098SERPINA1chr1494847208-FGGchr4155526218-0.0016355120.9983645

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Fusion Genomic Features for SERPINA1-FGG


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SERPINA1-FGG


check button Go to

FGviewer for the breakpoints of chr14:94847208-chr4:155526218

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.FGG

Q96C11

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneFGGchr14:94847208chr4:155526218ENST0000033609879400_422376.3333333333333454.0RegionNote=Gamma-chain polymerization%2C binding amino end of another fibrin alpha chain
TgeneFGGchr14:94847208chr4:155526218ENST0000033609879423_437376.3333333333333454.0RegionNote=Platelet aggregation and Staphylococcus clumping
TgeneFGGchr14:94847208chr4:155526218ENST00000404648710400_422376.3333333333333438.0RegionNote=Gamma-chain polymerization%2C binding amino end of another fibrin alpha chain
TgeneFGGchr14:94847208chr4:155526218ENST00000404648710423_437376.3333333333333438.0RegionNote=Platelet aggregation and Staphylococcus clumping

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSERPINA1chr14:94847208chr4:155526218ENST00000355814-35368_392305.6666666666667419.0RegionNote=RCL
HgeneSERPINA1chr14:94847208chr4:155526218ENST00000393087-35368_392305.6666666666667419.0RegionNote=RCL
HgeneSERPINA1chr14:94847208chr4:155526218ENST00000393088-57368_392305.6666666666667419.0RegionNote=RCL
HgeneSERPINA1chr14:94847208chr4:155526218ENST00000402629-34368_392305.6666666666667360.0RegionNote=RCL
HgeneSERPINA1chr14:94847208chr4:155526218ENST00000404814-46368_392305.6666666666667419.0RegionNote=RCL
HgeneSERPINA1chr14:94847208chr4:155526218ENST00000437397-46368_392305.6666666666667419.0RegionNote=RCL
HgeneSERPINA1chr14:94847208chr4:155526218ENST00000440909-35368_392305.6666666666667419.0RegionNote=RCL
HgeneSERPINA1chr14:94847208chr4:155526218ENST00000448921-57368_392305.6666666666667419.0RegionNote=RCL
HgeneSERPINA1chr14:94847208chr4:155526218ENST00000449399-46368_392305.6666666666667419.0RegionNote=RCL
TgeneFGGchr14:94847208chr4:155526218ENST0000033609879170_416376.3333333333333454.0DomainFibrinogen C-terminal
TgeneFGGchr14:94847208chr4:155526218ENST00000404648710170_416376.3333333333333438.0DomainFibrinogen C-terminal


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Fusion Gene Sequence for SERPINA1-FGG


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000355814_ENST00000336098_TCGA-FV-A23B-01A_SERPINA1_chr14_94847208_-_FGG_chr4_155526218_length(transcript)=1685nt_BP=1194nt
TGGGCAGGAACTGGGCACTGTGCCCAGGGCATGCACTGCCTCCACGCAGCAACCCTCAGAGTCCTGAGCTGAACCAAGAAGGAGGAGGGG
GTCGGGCCTCCGAGGAAGGCCTAGCCGCTGCTGCTGCCAGGAATTCCAGGTTGGAGGGGCGGCAACCTCCTGCCAGCCTTCAGGCCACTC
TCCTGTGCCTGCCAGAAGAGACAGAGCTTGAGGAGAGCTTGAGGAGAGCAGGAAAGGTGGGACATTGCTGCTGCTGCTCACTCAGTTCCA
CAGGACAATGCCGTCTTCTGTCTCGTGGGGCATCCTCCTGCTGGCAGGCCTGTGCTGCCTGGTCCCTGTCTCCCTGGCTGAGGATCCCCA
GGGAGATGCTGCCCAGAAGACAGATACATCCCACCATGATCAGGATCACCCAACCTTCAACAAGATCACCCCCAACCTGGCTGAGTTCGC
CTTCAGCCTATACCGCCAGCTGGCACACCAGTCCAACAGCACCAATATCTTCTTCTCCCCAGTGAGCATCGCTACAGCCTTTGCAATGCT
CTCCCTGGGGACCAAGGCTGACACTCACGATGAAATCCTGGAGGGCCTGAATTTCAACCTCACGGAGATTCCGGAGGCTCAGATCCATGA
AGGCTTCCAGGAACTCCTCCGTACCCTCAACCAGCCAGACAGCCAGCTCCAGCTGACCACCGGCAATGGCCTGTTCCTCAGCGAGGGCCT
GAAGCTAGTGGATAAGTTTTTGGAGGATGTTAAAAAGTTGTACCACTCAGAAGCCTTCACTGTCAACTTCGGGGACACCGAAGAGGCCAA
GAAACAGATCAACGATTACGTGGAGAAGGGTACTCAAGGGAAAATTGTGGATTTGGTCAAGGAGCTTGACAGAGACACAGTTTTTGCTCT
GGTGAATTACATCTTCTTTAAAGGCAAATGGGAGAGACCCTTTGAAGTCAAGGACACCGAGGAAGAGGACTTCCACGTGGACCAGGTGAC
CACCGTGAAGGTGCCTATGATGAAGCGTTTAGGCATGTTTAACATCCAGCACTGTAAGAAGCTGTCCAGCTGGGTGCTGCTGATGAAATA
CCTGGGCAATGCCACCGCCATCTTCTTCCTGCCTGATGAGGGGAAACTACAGCACCTGGAAAATGAACTCACCCACGATATCATCACCAA
GTTCCTGGAAAATGAAGACAGAAGGTGGCACTTACTCAAAAGCATCTACTCCTAATGGTTATGATAATGGCATTATTTGGGCCACTTGGA
AAACCCGGTGGTATTCCATGAAGAAAACCACTATGAAGATAATCCCATTCAACAGACTCACAATTGGAGAAGGACAGCAACACCACCTGG
GGGGAGCCAAACAGGTCAGACCAGAGCACCCTGCGGAAACAGAATATGACTCACTTTACCCTGAGGATGATTTGTAGAAAATTAACTGCT
AACTTCTATTGACCCACAAAGTTTCAGAAATTCTCTGAAAGTTTCTTCCTTTTTTCTCTTACTATATTTATTGATTTCAAGTCTTCTATT
AAGGACATTTAGCCTTCAATGGAAATTAAAACTCATTTAGGACTGTATTTCCAAATTACTGATATCAGAGTTATTTAAAAATTGTTTATT

>In-frame_ENST00000355814_ENST00000336098_TCGA-FV-A23B-01A_SERPINA1_chr14_94847208_-_FGG_chr4_155526218_length(amino acids)=326AA_start in transcript=244_stop in transcript=1224
MLLLLTQFHRTMPSSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPV
SIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTV
NFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKL

--------------------------------------------------------------
>In-frame_ENST00000393087_ENST00000336098_TCGA-FV-A23B-01A_SERPINA1_chr14_94847208_-_FGG_chr4_155526218_length(transcript)=1673nt_BP=1182nt
AGGTACAATGACTCCTTTCGGTAAGTGCAGTGGAAGCTGTACACTGCCCAGGCAAAGCGTCCGGGCAGCGTAGGCGGGCGACTCAGATCC
CAGCCAGTGGACTTAGCCCCTGTTTGCTCCTCCGATAACTGGGGTGACCTTGGTTAATATTCACCAGCAGCCTCCCCCGTTGCCCCTCTG
GATCCACTGCTTAAATACGGACGAGGACAGGGCCCTGTCTCCTCAGCTTCAGGCACCACCACTGACCTGGGACAGTGAATCGACAATGCC
GTCTTCTGTCTCGTGGGGCATCCTCCTGCTGGCAGGCCTGTGCTGCCTGGTCCCTGTCTCCCTGGCTGAGGATCCCCAGGGAGATGCTGC
CCAGAAGACAGATACATCCCACCATGATCAGGATCACCCAACCTTCAACAAGATCACCCCCAACCTGGCTGAGTTCGCCTTCAGCCTATA
CCGCCAGCTGGCACACCAGTCCAACAGCACCAATATCTTCTTCTCCCCAGTGAGCATCGCTACAGCCTTTGCAATGCTCTCCCTGGGGAC
CAAGGCTGACACTCACGATGAAATCCTGGAGGGCCTGAATTTCAACCTCACGGAGATTCCGGAGGCTCAGATCCATGAAGGCTTCCAGGA
ACTCCTCCGTACCCTCAACCAGCCAGACAGCCAGCTCCAGCTGACCACCGGCAATGGCCTGTTCCTCAGCGAGGGCCTGAAGCTAGTGGA
TAAGTTTTTGGAGGATGTTAAAAAGTTGTACCACTCAGAAGCCTTCACTGTCAACTTCGGGGACACCGAAGAGGCCAAGAAACAGATCAA
CGATTACGTGGAGAAGGGTACTCAAGGGAAAATTGTGGATTTGGTCAAGGAGCTTGACAGAGACACAGTTTTTGCTCTGGTGAATTACAT
CTTCTTTAAAGGCAAATGGGAGAGACCCTTTGAAGTCAAGGACACCGAGGAAGAGGACTTCCACGTGGACCAGGTGACCACCGTGAAGGT
GCCTATGATGAAGCGTTTAGGCATGTTTAACATCCAGCACTGTAAGAAGCTGTCCAGCTGGGTGCTGCTGATGAAATACCTGGGCAATGC
CACCGCCATCTTCTTCCTGCCTGATGAGGGGAAACTACAGCACCTGGAAAATGAACTCACCCACGATATCATCACCAAGTTCCTGGAAAA
TGAAGACAGAAGGTGGCACTTACTCAAAAGCATCTACTCCTAATGGTTATGATAATGGCATTATTTGGGCCACTTGGAAAACCCGGTGGT
ATTCCATGAAGAAAACCACTATGAAGATAATCCCATTCAACAGACTCACAATTGGAGAAGGACAGCAACACCACCTGGGGGGAGCCAAAC
AGGTCAGACCAGAGCACCCTGCGGAAACAGAATATGACTCACTTTACCCTGAGGATGATTTGTAGAAAATTAACTGCTAACTTCTATTGA
CCCACAAAGTTTCAGAAATTCTCTGAAAGTTTCTTCCTTTTTTCTCTTACTATATTTATTGATTTCAAGTCTTCTATTAAGGACATTTAG
CCTTCAATGGAAATTAAAACTCATTTAGGACTGTATTTCCAAATTACTGATATCAGAGTTATTTAAAAATTGTTTATTTGAGGAGATAAC

>In-frame_ENST00000393087_ENST00000336098_TCGA-FV-A23B-01A_SERPINA1_chr14_94847208_-_FGG_chr4_155526218_length(amino acids)=367AA_start in transcript=109_stop in transcript=1212
MFAPPITGVTLVNIHQQPPPLPLWIHCLNTDEDRALSPQLQAPPLTWDSESTMPSSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTS
HHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLN
QPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKW
ERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRRWH

--------------------------------------------------------------
>In-frame_ENST00000393088_ENST00000404648_TCGA-FV-A23B-01A_SERPINA1_chr14_94847208_-_FGG_chr4_155526218_length(transcript)=1863nt_BP=1472nt
GTGGGCAGGAACTGGGCACTGTGCCCAGGGCATGCACTGCCTCCACGCAGCAACCCTCAGAGTCCTGAGCTGAACCAAGAAGGAGGAGGG
GGTCGGGCCTCCGAGGAAGGCCTAGCCGCTGCTGCTGCCAGGAATTCCAGGTTGGAGGGGCGGCAACCTCCTGCCAGCCTTCAGGCCACT
CTCCTGTGCCTGCCAGAAGAGACAGAGCTTGAGGAGAGCTTGAGGAGAGCAGGAAAGGGCGGCAGTAAGTCTTCAGCATCAGGCATTTTG
GGGTGACTCAGTAAATGGTAGATCTTGCTACCAGTGGAACAGCCACTAAGGATTCTGCAGTGAGAGCAGAGGGCCAGCTAAGTGGTACTC
TCCCAGAGACTGTCTGACTCACGCCACCCCCTCCACCTTGGACACAGGACGCTGTGGTTTCTGAGCCAGGTACAATGACTCCTTTCGCAG
CCTCCCCCGTTGCCCCTCTGGATCCACTGCTTAAATACGGACGAGGACAGGGCCCTGTCTCCTCAGCTTCAGGCACCACCACTGACCTGG
GACAGTGAATCGACAATGCCGTCTTCTGTCTCGTGGGGCATCCTCCTGCTGGCAGGCCTGTGCTGCCTGGTCCCTGTCTCCCTGGCTGAG
GATCCCCAGGGAGATGCTGCCCAGAAGACAGATACATCCCACCATGATCAGGATCACCCAACCTTCAACAAGATCACCCCCAACCTGGCT
GAGTTCGCCTTCAGCCTATACCGCCAGCTGGCACACCAGTCCAACAGCACCAATATCTTCTTCTCCCCAGTGAGCATCGCTACAGCCTTT
GCAATGCTCTCCCTGGGGACCAAGGCTGACACTCACGATGAAATCCTGGAGGGCCTGAATTTCAACCTCACGGAGATTCCGGAGGCTCAG
ATCCATGAAGGCTTCCAGGAACTCCTCCGTACCCTCAACCAGCCAGACAGCCAGCTCCAGCTGACCACCGGCAATGGCCTGTTCCTCAGC
GAGGGCCTGAAGCTAGTGGATAAGTTTTTGGAGGATGTTAAAAAGTTGTACCACTCAGAAGCCTTCACTGTCAACTTCGGGGACACCGAA
GAGGCCAAGAAACAGATCAACGATTACGTGGAGAAGGGTACTCAAGGGAAAATTGTGGATTTGGTCAAGGAGCTTGACAGAGACACAGTT
TTTGCTCTGGTGAATTACATCTTCTTTAAAGGCAAATGGGAGAGACCCTTTGAAGTCAAGGACACCGAGGAAGAGGACTTCCACGTGGAC
CAGGTGACCACCGTGAAGGTGCCTATGATGAAGCGTTTAGGCATGTTTAACATCCAGCACTGTAAGAAGCTGTCCAGCTGGGTGCTGCTG
ATGAAATACCTGGGCAATGCCACCGCCATCTTCTTCCTGCCTGATGAGGGGAAACTACAGCACCTGGAAAATGAACTCACCCACGATATC
ATCACCAAGTTCCTGGAAAATGAAGACAGAAGGTGGCACTTACTCAAAAGCATCTACTCCTAATGGTTATGATAATGGCATTATTTGGGC
CACTTGGAAAACCCGGTGGTATTCCATGAAGAAAACCACTATGAAGATAATCCCATTCAACAGACTCACAATTGGAGAAGGACAGCAACA
CCACCTGGGGGGAGCCAAACAGGCTGGAGACGTTTAAAAGACCGTTTCAAAAGAGATTTACTTTTTTAAAGGACTTTATCTGAACAGAGA
GATATAATATTTTTCCTATTGGACAATGGACTTGCAAAGCTTCACTTCATTTTAAGAGCAAAAGACCCCATGTTGAAAACTCCATAACAG

>In-frame_ENST00000393088_ENST00000404648_TCGA-FV-A23B-01A_SERPINA1_chr14_94847208_-_FGG_chr4_155526218_length(amino acids)=347AA_start in transcript=459_stop in transcript=1502
MPLWIHCLNTDEDRALSPQLQAPPLTWDSESTMPSSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFA
FSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGL
KLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVT

--------------------------------------------------------------
>In-frame_ENST00000393088_ENST00000405164_TCGA-FV-A23B-01A_SERPINA1_chr14_94847208_-_FGG_chr4_155526218_length(transcript)=1824nt_BP=1472nt
GTGGGCAGGAACTGGGCACTGTGCCCAGGGCATGCACTGCCTCCACGCAGCAACCCTCAGAGTCCTGAGCTGAACCAAGAAGGAGGAGGG
GGTCGGGCCTCCGAGGAAGGCCTAGCCGCTGCTGCTGCCAGGAATTCCAGGTTGGAGGGGCGGCAACCTCCTGCCAGCCTTCAGGCCACT
CTCCTGTGCCTGCCAGAAGAGACAGAGCTTGAGGAGAGCTTGAGGAGAGCAGGAAAGGGCGGCAGTAAGTCTTCAGCATCAGGCATTTTG
GGGTGACTCAGTAAATGGTAGATCTTGCTACCAGTGGAACAGCCACTAAGGATTCTGCAGTGAGAGCAGAGGGCCAGCTAAGTGGTACTC
TCCCAGAGACTGTCTGACTCACGCCACCCCCTCCACCTTGGACACAGGACGCTGTGGTTTCTGAGCCAGGTACAATGACTCCTTTCGCAG
CCTCCCCCGTTGCCCCTCTGGATCCACTGCTTAAATACGGACGAGGACAGGGCCCTGTCTCCTCAGCTTCAGGCACCACCACTGACCTGG
GACAGTGAATCGACAATGCCGTCTTCTGTCTCGTGGGGCATCCTCCTGCTGGCAGGCCTGTGCTGCCTGGTCCCTGTCTCCCTGGCTGAG
GATCCCCAGGGAGATGCTGCCCAGAAGACAGATACATCCCACCATGATCAGGATCACCCAACCTTCAACAAGATCACCCCCAACCTGGCT
GAGTTCGCCTTCAGCCTATACCGCCAGCTGGCACACCAGTCCAACAGCACCAATATCTTCTTCTCCCCAGTGAGCATCGCTACAGCCTTT
GCAATGCTCTCCCTGGGGACCAAGGCTGACACTCACGATGAAATCCTGGAGGGCCTGAATTTCAACCTCACGGAGATTCCGGAGGCTCAG
ATCCATGAAGGCTTCCAGGAACTCCTCCGTACCCTCAACCAGCCAGACAGCCAGCTCCAGCTGACCACCGGCAATGGCCTGTTCCTCAGC
GAGGGCCTGAAGCTAGTGGATAAGTTTTTGGAGGATGTTAAAAAGTTGTACCACTCAGAAGCCTTCACTGTCAACTTCGGGGACACCGAA
GAGGCCAAGAAACAGATCAACGATTACGTGGAGAAGGGTACTCAAGGGAAAATTGTGGATTTGGTCAAGGAGCTTGACAGAGACACAGTT
TTTGCTCTGGTGAATTACATCTTCTTTAAAGGCAAATGGGAGAGACCCTTTGAAGTCAAGGACACCGAGGAAGAGGACTTCCACGTGGAC
CAGGTGACCACCGTGAAGGTGCCTATGATGAAGCGTTTAGGCATGTTTAACATCCAGCACTGTAAGAAGCTGTCCAGCTGGGTGCTGCTG
ATGAAATACCTGGGCAATGCCACCGCCATCTTCTTCCTGCCTGATGAGGGGAAACTACAGCACCTGGAAAATGAACTCACCCACGATATC
ATCACCAAGTTCCTGGAAAATGAAGACAGAAGGTGGCACTTACTCAAAAGCATCTACTCCTAATGGTTATGATAATGGCATTATTTGGGC
CACTTGGAAAACCCGGTGGTATTCCATGAAGAAAACCACTATGAAGATAATCCCATTCAACAGACTCACAATTGGAGAAGGACAGCAACA
CCACCTGGGGGGAGCCAAACAGGCTGGAGACGTTTAAAAGACCGTTTCAAAAGAGATTTACTTTTTTAAAGGACTTTATCTGAACAGAGA
GATATAATATTTTTCCTATTGGACAATGGACTTGCAAAGCTTCACTTCATTTTAAGAGCAAAAGACCCCATGTTGAAAACTCCATAACAG

>In-frame_ENST00000393088_ENST00000405164_TCGA-FV-A23B-01A_SERPINA1_chr14_94847208_-_FGG_chr4_155526218_length(amino acids)=347AA_start in transcript=459_stop in transcript=1502
MPLWIHCLNTDEDRALSPQLQAPPLTWDSESTMPSSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFA
FSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGL
KLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVT

--------------------------------------------------------------
>In-frame_ENST00000393088_ENST00000407946_TCGA-FV-A23B-01A_SERPINA1_chr14_94847208_-_FGG_chr4_155526218_length(transcript)=1929nt_BP=1472nt
GTGGGCAGGAACTGGGCACTGTGCCCAGGGCATGCACTGCCTCCACGCAGCAACCCTCAGAGTCCTGAGCTGAACCAAGAAGGAGGAGGG
GGTCGGGCCTCCGAGGAAGGCCTAGCCGCTGCTGCTGCCAGGAATTCCAGGTTGGAGGGGCGGCAACCTCCTGCCAGCCTTCAGGCCACT
CTCCTGTGCCTGCCAGAAGAGACAGAGCTTGAGGAGAGCTTGAGGAGAGCAGGAAAGGGCGGCAGTAAGTCTTCAGCATCAGGCATTTTG
GGGTGACTCAGTAAATGGTAGATCTTGCTACCAGTGGAACAGCCACTAAGGATTCTGCAGTGAGAGCAGAGGGCCAGCTAAGTGGTACTC
TCCCAGAGACTGTCTGACTCACGCCACCCCCTCCACCTTGGACACAGGACGCTGTGGTTTCTGAGCCAGGTACAATGACTCCTTTCGCAG
CCTCCCCCGTTGCCCCTCTGGATCCACTGCTTAAATACGGACGAGGACAGGGCCCTGTCTCCTCAGCTTCAGGCACCACCACTGACCTGG
GACAGTGAATCGACAATGCCGTCTTCTGTCTCGTGGGGCATCCTCCTGCTGGCAGGCCTGTGCTGCCTGGTCCCTGTCTCCCTGGCTGAG
GATCCCCAGGGAGATGCTGCCCAGAAGACAGATACATCCCACCATGATCAGGATCACCCAACCTTCAACAAGATCACCCCCAACCTGGCT
GAGTTCGCCTTCAGCCTATACCGCCAGCTGGCACACCAGTCCAACAGCACCAATATCTTCTTCTCCCCAGTGAGCATCGCTACAGCCTTT
GCAATGCTCTCCCTGGGGACCAAGGCTGACACTCACGATGAAATCCTGGAGGGCCTGAATTTCAACCTCACGGAGATTCCGGAGGCTCAG
ATCCATGAAGGCTTCCAGGAACTCCTCCGTACCCTCAACCAGCCAGACAGCCAGCTCCAGCTGACCACCGGCAATGGCCTGTTCCTCAGC
GAGGGCCTGAAGCTAGTGGATAAGTTTTTGGAGGATGTTAAAAAGTTGTACCACTCAGAAGCCTTCACTGTCAACTTCGGGGACACCGAA
GAGGCCAAGAAACAGATCAACGATTACGTGGAGAAGGGTACTCAAGGGAAAATTGTGGATTTGGTCAAGGAGCTTGACAGAGACACAGTT
TTTGCTCTGGTGAATTACATCTTCTTTAAAGGCAAATGGGAGAGACCCTTTGAAGTCAAGGACACCGAGGAAGAGGACTTCCACGTGGAC
CAGGTGACCACCGTGAAGGTGCCTATGATGAAGCGTTTAGGCATGTTTAACATCCAGCACTGTAAGAAGCTGTCCAGCTGGGTGCTGCTG
ATGAAATACCTGGGCAATGCCACCGCCATCTTCTTCCTGCCTGATGAGGGGAAACTACAGCACCTGGAAAATGAACTCACCCACGATATC
ATCACCAAGTTCCTGGAAAATGAAGACAGAAGGTGGCACTTACTCAAAAGCATCTACTCCTAATGGTTATGATAATGGCATTATTTGGGC
CACTTGGAAAACCCGGTGGTATTCCATGAAGAAAACCACTATGAAGATAATCCCATTCAACAGACTCACAATTGGAGAAGGACAGCAACA
CCACCTGGGGGGAGCCAAACAGGTCAGACCAGAGCACCCTGCGGAAACAGAATATGACTCACTTTACCCTGAGGATGATTTGTAGAAAAT
TAACTGCTAACTTCTATTGACCCACAAAGTTTCAGAAATTCTCTGAAAGTTTCTTCCTTTTTTCTCTTACTATATTTATTGATTTCAAGT
CTTCTATTAAGGACATTTAGCCTTCAATGGAAATTAAAACTCATTTAGGACTGTATTTCCAAATTACTGATATCAGAGTTATTTAAAAAT

>In-frame_ENST00000393088_ENST00000407946_TCGA-FV-A23B-01A_SERPINA1_chr14_94847208_-_FGG_chr4_155526218_length(amino acids)=347AA_start in transcript=459_stop in transcript=1502
MPLWIHCLNTDEDRALSPQLQAPPLTWDSESTMPSSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFA
FSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGL
KLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVT

--------------------------------------------------------------
>In-frame_ENST00000404814_ENST00000404648_TCGA-FV-A23B-01A_SERPINA1_chr14_94847208_-_FGG_chr4_155526218_length(transcript)=1619nt_BP=1228nt
ATGCACTGCCTCCACGCAGCAACCCTCAGAGTCCTGAGCTGAACCAAGAAGGAGGAGGGGGTCGGGCCTCCGAGGAAGGCCTAGCCGCTG
CTGCTGCCAGGAATTCCAGGTTGGAGGGGCGGCAACCTCCTGCCAGCCTTCAGGCCACTCTCCTGTGCCTGCCAGAAGAGACAGAGCTTG
AGGAGAGCTTGAGGAGAGCAGGAAAGCCTCCCCCGTTGCCCCTCTGGATCCACTGCTTAAATACGGACGAGGACAGGGCCCTGTCTCCTC
AGCTTCAGGCACCACCACTGACCTGGGACAGTGAATCGACAATGCCGTCTTCTGTCTCGTGGGGCATCCTCCTGCTGGCAGGCCTGTGCT
GCCTGGTCCCTGTCTCCCTGGCTGAGGATCCCCAGGGAGATGCTGCCCAGAAGACAGATACATCCCACCATGATCAGGATCACCCAACCT
TCAACAAGATCACCCCCAACCTGGCTGAGTTCGCCTTCAGCCTATACCGCCAGCTGGCACACCAGTCCAACAGCACCAATATCTTCTTCT
CCCCAGTGAGCATCGCTACAGCCTTTGCAATGCTCTCCCTGGGGACCAAGGCTGACACTCACGATGAAATCCTGGAGGGCCTGAATTTCA
ACCTCACGGAGATTCCGGAGGCTCAGATCCATGAAGGCTTCCAGGAACTCCTCCGTACCCTCAACCAGCCAGACAGCCAGCTCCAGCTGA
CCACCGGCAATGGCCTGTTCCTCAGCGAGGGCCTGAAGCTAGTGGATAAGTTTTTGGAGGATGTTAAAAAGTTGTACCACTCAGAAGCCT
TCACTGTCAACTTCGGGGACACCGAAGAGGCCAAGAAACAGATCAACGATTACGTGGAGAAGGGTACTCAAGGGAAAATTGTGGATTTGG
TCAAGGAGCTTGACAGAGACACAGTTTTTGCTCTGGTGAATTACATCTTCTTTAAAGGCAAATGGGAGAGACCCTTTGAAGTCAAGGACA
CCGAGGAAGAGGACTTCCACGTGGACCAGGTGACCACCGTGAAGGTGCCTATGATGAAGCGTTTAGGCATGTTTAACATCCAGCACTGTA
AGAAGCTGTCCAGCTGGGTGCTGCTGATGAAATACCTGGGCAATGCCACCGCCATCTTCTTCCTGCCTGATGAGGGGAAACTACAGCACC
TGGAAAATGAACTCACCCACGATATCATCACCAAGTTCCTGGAAAATGAAGACAGAAGGTGGCACTTACTCAAAAGCATCTACTCCTAAT
GGTTATGATAATGGCATTATTTGGGCCACTTGGAAAACCCGGTGGTATTCCATGAAGAAAACCACTATGAAGATAATCCCATTCAACAGA
CTCACAATTGGAGAAGGACAGCAACACCACCTGGGGGGAGCCAAACAGGCTGGAGACGTTTAAAAGACCGTTTCAAAAGAGATTTACTTT
TTTAAAGGACTTTATCTGAACAGAGAGATATAATATTTTTCCTATTGGACAATGGACTTGCAAAGCTTCACTTCATTTTAAGAGCAAAAG

>In-frame_ENST00000404814_ENST00000404648_TCGA-FV-A23B-01A_SERPINA1_chr14_94847208_-_FGG_chr4_155526218_length(amino acids)=417AA_start in transcript=5_stop in transcript=1258
MPPRSNPQSPELNQEGGGGRASEEGLAAAAARNSRLEGRQPPASLQATLLCLPEETELEESLRRAGKPPPLPLWIHCLNTDEDRALSPQL
QAPPLTWDSESTMPSSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSP
VSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFT
VNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKK

--------------------------------------------------------------
>In-frame_ENST00000404814_ENST00000405164_TCGA-FV-A23B-01A_SERPINA1_chr14_94847208_-_FGG_chr4_155526218_length(transcript)=1580nt_BP=1228nt
ATGCACTGCCTCCACGCAGCAACCCTCAGAGTCCTGAGCTGAACCAAGAAGGAGGAGGGGGTCGGGCCTCCGAGGAAGGCCTAGCCGCTG
CTGCTGCCAGGAATTCCAGGTTGGAGGGGCGGCAACCTCCTGCCAGCCTTCAGGCCACTCTCCTGTGCCTGCCAGAAGAGACAGAGCTTG
AGGAGAGCTTGAGGAGAGCAGGAAAGCCTCCCCCGTTGCCCCTCTGGATCCACTGCTTAAATACGGACGAGGACAGGGCCCTGTCTCCTC
AGCTTCAGGCACCACCACTGACCTGGGACAGTGAATCGACAATGCCGTCTTCTGTCTCGTGGGGCATCCTCCTGCTGGCAGGCCTGTGCT
GCCTGGTCCCTGTCTCCCTGGCTGAGGATCCCCAGGGAGATGCTGCCCAGAAGACAGATACATCCCACCATGATCAGGATCACCCAACCT
TCAACAAGATCACCCCCAACCTGGCTGAGTTCGCCTTCAGCCTATACCGCCAGCTGGCACACCAGTCCAACAGCACCAATATCTTCTTCT
CCCCAGTGAGCATCGCTACAGCCTTTGCAATGCTCTCCCTGGGGACCAAGGCTGACACTCACGATGAAATCCTGGAGGGCCTGAATTTCA
ACCTCACGGAGATTCCGGAGGCTCAGATCCATGAAGGCTTCCAGGAACTCCTCCGTACCCTCAACCAGCCAGACAGCCAGCTCCAGCTGA
CCACCGGCAATGGCCTGTTCCTCAGCGAGGGCCTGAAGCTAGTGGATAAGTTTTTGGAGGATGTTAAAAAGTTGTACCACTCAGAAGCCT
TCACTGTCAACTTCGGGGACACCGAAGAGGCCAAGAAACAGATCAACGATTACGTGGAGAAGGGTACTCAAGGGAAAATTGTGGATTTGG
TCAAGGAGCTTGACAGAGACACAGTTTTTGCTCTGGTGAATTACATCTTCTTTAAAGGCAAATGGGAGAGACCCTTTGAAGTCAAGGACA
CCGAGGAAGAGGACTTCCACGTGGACCAGGTGACCACCGTGAAGGTGCCTATGATGAAGCGTTTAGGCATGTTTAACATCCAGCACTGTA
AGAAGCTGTCCAGCTGGGTGCTGCTGATGAAATACCTGGGCAATGCCACCGCCATCTTCTTCCTGCCTGATGAGGGGAAACTACAGCACC
TGGAAAATGAACTCACCCACGATATCATCACCAAGTTCCTGGAAAATGAAGACAGAAGGTGGCACTTACTCAAAAGCATCTACTCCTAAT
GGTTATGATAATGGCATTATTTGGGCCACTTGGAAAACCCGGTGGTATTCCATGAAGAAAACCACTATGAAGATAATCCCATTCAACAGA
CTCACAATTGGAGAAGGACAGCAACACCACCTGGGGGGAGCCAAACAGGCTGGAGACGTTTAAAAGACCGTTTCAAAAGAGATTTACTTT
TTTAAAGGACTTTATCTGAACAGAGAGATATAATATTTTTCCTATTGGACAATGGACTTGCAAAGCTTCACTTCATTTTAAGAGCAAAAG

>In-frame_ENST00000404814_ENST00000405164_TCGA-FV-A23B-01A_SERPINA1_chr14_94847208_-_FGG_chr4_155526218_length(amino acids)=417AA_start in transcript=5_stop in transcript=1258
MPPRSNPQSPELNQEGGGGRASEEGLAAAAARNSRLEGRQPPASLQATLLCLPEETELEESLRRAGKPPPLPLWIHCLNTDEDRALSPQL
QAPPLTWDSESTMPSSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSP
VSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFT
VNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKK

--------------------------------------------------------------
>In-frame_ENST00000404814_ENST00000407946_TCGA-FV-A23B-01A_SERPINA1_chr14_94847208_-_FGG_chr4_155526218_length(transcript)=1685nt_BP=1228nt
ATGCACTGCCTCCACGCAGCAACCCTCAGAGTCCTGAGCTGAACCAAGAAGGAGGAGGGGGTCGGGCCTCCGAGGAAGGCCTAGCCGCTG
CTGCTGCCAGGAATTCCAGGTTGGAGGGGCGGCAACCTCCTGCCAGCCTTCAGGCCACTCTCCTGTGCCTGCCAGAAGAGACAGAGCTTG
AGGAGAGCTTGAGGAGAGCAGGAAAGCCTCCCCCGTTGCCCCTCTGGATCCACTGCTTAAATACGGACGAGGACAGGGCCCTGTCTCCTC
AGCTTCAGGCACCACCACTGACCTGGGACAGTGAATCGACAATGCCGTCTTCTGTCTCGTGGGGCATCCTCCTGCTGGCAGGCCTGTGCT
GCCTGGTCCCTGTCTCCCTGGCTGAGGATCCCCAGGGAGATGCTGCCCAGAAGACAGATACATCCCACCATGATCAGGATCACCCAACCT
TCAACAAGATCACCCCCAACCTGGCTGAGTTCGCCTTCAGCCTATACCGCCAGCTGGCACACCAGTCCAACAGCACCAATATCTTCTTCT
CCCCAGTGAGCATCGCTACAGCCTTTGCAATGCTCTCCCTGGGGACCAAGGCTGACACTCACGATGAAATCCTGGAGGGCCTGAATTTCA
ACCTCACGGAGATTCCGGAGGCTCAGATCCATGAAGGCTTCCAGGAACTCCTCCGTACCCTCAACCAGCCAGACAGCCAGCTCCAGCTGA
CCACCGGCAATGGCCTGTTCCTCAGCGAGGGCCTGAAGCTAGTGGATAAGTTTTTGGAGGATGTTAAAAAGTTGTACCACTCAGAAGCCT
TCACTGTCAACTTCGGGGACACCGAAGAGGCCAAGAAACAGATCAACGATTACGTGGAGAAGGGTACTCAAGGGAAAATTGTGGATTTGG
TCAAGGAGCTTGACAGAGACACAGTTTTTGCTCTGGTGAATTACATCTTCTTTAAAGGCAAATGGGAGAGACCCTTTGAAGTCAAGGACA
CCGAGGAAGAGGACTTCCACGTGGACCAGGTGACCACCGTGAAGGTGCCTATGATGAAGCGTTTAGGCATGTTTAACATCCAGCACTGTA
AGAAGCTGTCCAGCTGGGTGCTGCTGATGAAATACCTGGGCAATGCCACCGCCATCTTCTTCCTGCCTGATGAGGGGAAACTACAGCACC
TGGAAAATGAACTCACCCACGATATCATCACCAAGTTCCTGGAAAATGAAGACAGAAGGTGGCACTTACTCAAAAGCATCTACTCCTAAT
GGTTATGATAATGGCATTATTTGGGCCACTTGGAAAACCCGGTGGTATTCCATGAAGAAAACCACTATGAAGATAATCCCATTCAACAGA
CTCACAATTGGAGAAGGACAGCAACACCACCTGGGGGGAGCCAAACAGGTCAGACCAGAGCACCCTGCGGAAACAGAATATGACTCACTT
TACCCTGAGGATGATTTGTAGAAAATTAACTGCTAACTTCTATTGACCCACAAAGTTTCAGAAATTCTCTGAAAGTTTCTTCCTTTTTTC
TCTTACTATATTTATTGATTTCAAGTCTTCTATTAAGGACATTTAGCCTTCAATGGAAATTAAAACTCATTTAGGACTGTATTTCCAAAT

>In-frame_ENST00000404814_ENST00000407946_TCGA-FV-A23B-01A_SERPINA1_chr14_94847208_-_FGG_chr4_155526218_length(amino acids)=417AA_start in transcript=5_stop in transcript=1258
MPPRSNPQSPELNQEGGGGRASEEGLAAAAARNSRLEGRQPPASLQATLLCLPEETELEESLRRAGKPPPLPLWIHCLNTDEDRALSPQL
QAPPLTWDSESTMPSSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSP
VSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFT
VNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKK

--------------------------------------------------------------
>In-frame_ENST00000449399_ENST00000404648_TCGA-FV-A23B-01A_SERPINA1_chr14_94847208_-_FGG_chr4_155526218_length(transcript)=1610nt_BP=1219nt
CACGCAGCAACCCTCAGAGTCCTGAGCTGAACCAAGAAGGAGGAGGGGGTCGGGCCTCCGAGGAAGGCCTAGCCGCTGCTGCTGCCAGGA
ATTCCAGGTTGGAGGGGCGGCAACCTCCTGCCAGCCTTCAGGCCACTCTCCTGTGCCTGCCAGAAGAGACAGAGCTTGAGGAGAGCTTGA
GGAGAGCAGGAAAGCAGCCTCCCCCGTTGCCCCTCTGGATCCACTGCTTAAATACGGACGAGGACAGGGCCCTGTCTCCTCAGCTTCAGG
CACCACCACTGACCTGGGACAGTGAATCGACAATGCCGTCTTCTGTCTCGTGGGGCATCCTCCTGCTGGCAGGCCTGTGCTGCCTGGTCC
CTGTCTCCCTGGCTGAGGATCCCCAGGGAGATGCTGCCCAGAAGACAGATACATCCCACCATGATCAGGATCACCCAACCTTCAACAAGA
TCACCCCCAACCTGGCTGAGTTCGCCTTCAGCCTATACCGCCAGCTGGCACACCAGTCCAACAGCACCAATATCTTCTTCTCCCCAGTGA
GCATCGCTACAGCCTTTGCAATGCTCTCCCTGGGGACCAAGGCTGACACTCACGATGAAATCCTGGAGGGCCTGAATTTCAACCTCACGG
AGATTCCGGAGGCTCAGATCCATGAAGGCTTCCAGGAACTCCTCCGTACCCTCAACCAGCCAGACAGCCAGCTCCAGCTGACCACCGGCA
ATGGCCTGTTCCTCAGCGAGGGCCTGAAGCTAGTGGATAAGTTTTTGGAGGATGTTAAAAAGTTGTACCACTCAGAAGCCTTCACTGTCA
ACTTCGGGGACACCGAAGAGGCCAAGAAACAGATCAACGATTACGTGGAGAAGGGTACTCAAGGGAAAATTGTGGATTTGGTCAAGGAGC
TTGACAGAGACACAGTTTTTGCTCTGGTGAATTACATCTTCTTTAAAGGCAAATGGGAGAGACCCTTTGAAGTCAAGGACACCGAGGAAG
AGGACTTCCACGTGGACCAGGTGACCACCGTGAAGGTGCCTATGATGAAGCGTTTAGGCATGTTTAACATCCAGCACTGTAAGAAGCTGT
CCAGCTGGGTGCTGCTGATGAAATACCTGGGCAATGCCACCGCCATCTTCTTCCTGCCTGATGAGGGGAAACTACAGCACCTGGAAAATG
AACTCACCCACGATATCATCACCAAGTTCCTGGAAAATGAAGACAGAAGGTGGCACTTACTCAAAAGCATCTACTCCTAATGGTTATGAT
AATGGCATTATTTGGGCCACTTGGAAAACCCGGTGGTATTCCATGAAGAAAACCACTATGAAGATAATCCCATTCAACAGACTCACAATT
GGAGAAGGACAGCAACACCACCTGGGGGGAGCCAAACAGGCTGGAGACGTTTAAAAGACCGTTTCAAAAGAGATTTACTTTTTTAAAGGA
CTTTATCTGAACAGAGAGATATAATATTTTTCCTATTGGACAATGGACTTGCAAAGCTTCACTTCATTTTAAGAGCAAAAGACCCCATGT

>In-frame_ENST00000449399_ENST00000404648_TCGA-FV-A23B-01A_SERPINA1_chr14_94847208_-_FGG_chr4_155526218_length(amino acids)=407AA_start in transcript=26_stop in transcript=1249
MNQEGGGGRASEEGLAAAAARNSRLEGRQPPASLQATLLCLPEETELEESLRRAGKQPPPLPLWIHCLNTDEDRALSPQLQAPPLTWDSE
STMPSSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAML
SLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAK
KQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKY

--------------------------------------------------------------
>In-frame_ENST00000449399_ENST00000405164_TCGA-FV-A23B-01A_SERPINA1_chr14_94847208_-_FGG_chr4_155526218_length(transcript)=1571nt_BP=1219nt
CACGCAGCAACCCTCAGAGTCCTGAGCTGAACCAAGAAGGAGGAGGGGGTCGGGCCTCCGAGGAAGGCCTAGCCGCTGCTGCTGCCAGGA
ATTCCAGGTTGGAGGGGCGGCAACCTCCTGCCAGCCTTCAGGCCACTCTCCTGTGCCTGCCAGAAGAGACAGAGCTTGAGGAGAGCTTGA
GGAGAGCAGGAAAGCAGCCTCCCCCGTTGCCCCTCTGGATCCACTGCTTAAATACGGACGAGGACAGGGCCCTGTCTCCTCAGCTTCAGG
CACCACCACTGACCTGGGACAGTGAATCGACAATGCCGTCTTCTGTCTCGTGGGGCATCCTCCTGCTGGCAGGCCTGTGCTGCCTGGTCC
CTGTCTCCCTGGCTGAGGATCCCCAGGGAGATGCTGCCCAGAAGACAGATACATCCCACCATGATCAGGATCACCCAACCTTCAACAAGA
TCACCCCCAACCTGGCTGAGTTCGCCTTCAGCCTATACCGCCAGCTGGCACACCAGTCCAACAGCACCAATATCTTCTTCTCCCCAGTGA
GCATCGCTACAGCCTTTGCAATGCTCTCCCTGGGGACCAAGGCTGACACTCACGATGAAATCCTGGAGGGCCTGAATTTCAACCTCACGG
AGATTCCGGAGGCTCAGATCCATGAAGGCTTCCAGGAACTCCTCCGTACCCTCAACCAGCCAGACAGCCAGCTCCAGCTGACCACCGGCA
ATGGCCTGTTCCTCAGCGAGGGCCTGAAGCTAGTGGATAAGTTTTTGGAGGATGTTAAAAAGTTGTACCACTCAGAAGCCTTCACTGTCA
ACTTCGGGGACACCGAAGAGGCCAAGAAACAGATCAACGATTACGTGGAGAAGGGTACTCAAGGGAAAATTGTGGATTTGGTCAAGGAGC
TTGACAGAGACACAGTTTTTGCTCTGGTGAATTACATCTTCTTTAAAGGCAAATGGGAGAGACCCTTTGAAGTCAAGGACACCGAGGAAG
AGGACTTCCACGTGGACCAGGTGACCACCGTGAAGGTGCCTATGATGAAGCGTTTAGGCATGTTTAACATCCAGCACTGTAAGAAGCTGT
CCAGCTGGGTGCTGCTGATGAAATACCTGGGCAATGCCACCGCCATCTTCTTCCTGCCTGATGAGGGGAAACTACAGCACCTGGAAAATG
AACTCACCCACGATATCATCACCAAGTTCCTGGAAAATGAAGACAGAAGGTGGCACTTACTCAAAAGCATCTACTCCTAATGGTTATGAT
AATGGCATTATTTGGGCCACTTGGAAAACCCGGTGGTATTCCATGAAGAAAACCACTATGAAGATAATCCCATTCAACAGACTCACAATT
GGAGAAGGACAGCAACACCACCTGGGGGGAGCCAAACAGGCTGGAGACGTTTAAAAGACCGTTTCAAAAGAGATTTACTTTTTTAAAGGA
CTTTATCTGAACAGAGAGATATAATATTTTTCCTATTGGACAATGGACTTGCAAAGCTTCACTTCATTTTAAGAGCAAAAGACCCCATGT

>In-frame_ENST00000449399_ENST00000405164_TCGA-FV-A23B-01A_SERPINA1_chr14_94847208_-_FGG_chr4_155526218_length(amino acids)=407AA_start in transcript=26_stop in transcript=1249
MNQEGGGGRASEEGLAAAAARNSRLEGRQPPASLQATLLCLPEETELEESLRRAGKQPPPLPLWIHCLNTDEDRALSPQLQAPPLTWDSE
STMPSSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAML
SLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAK
KQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKY

--------------------------------------------------------------
>In-frame_ENST00000449399_ENST00000407946_TCGA-FV-A23B-01A_SERPINA1_chr14_94847208_-_FGG_chr4_155526218_length(transcript)=1676nt_BP=1219nt
CACGCAGCAACCCTCAGAGTCCTGAGCTGAACCAAGAAGGAGGAGGGGGTCGGGCCTCCGAGGAAGGCCTAGCCGCTGCTGCTGCCAGGA
ATTCCAGGTTGGAGGGGCGGCAACCTCCTGCCAGCCTTCAGGCCACTCTCCTGTGCCTGCCAGAAGAGACAGAGCTTGAGGAGAGCTTGA
GGAGAGCAGGAAAGCAGCCTCCCCCGTTGCCCCTCTGGATCCACTGCTTAAATACGGACGAGGACAGGGCCCTGTCTCCTCAGCTTCAGG
CACCACCACTGACCTGGGACAGTGAATCGACAATGCCGTCTTCTGTCTCGTGGGGCATCCTCCTGCTGGCAGGCCTGTGCTGCCTGGTCC
CTGTCTCCCTGGCTGAGGATCCCCAGGGAGATGCTGCCCAGAAGACAGATACATCCCACCATGATCAGGATCACCCAACCTTCAACAAGA
TCACCCCCAACCTGGCTGAGTTCGCCTTCAGCCTATACCGCCAGCTGGCACACCAGTCCAACAGCACCAATATCTTCTTCTCCCCAGTGA
GCATCGCTACAGCCTTTGCAATGCTCTCCCTGGGGACCAAGGCTGACACTCACGATGAAATCCTGGAGGGCCTGAATTTCAACCTCACGG
AGATTCCGGAGGCTCAGATCCATGAAGGCTTCCAGGAACTCCTCCGTACCCTCAACCAGCCAGACAGCCAGCTCCAGCTGACCACCGGCA
ATGGCCTGTTCCTCAGCGAGGGCCTGAAGCTAGTGGATAAGTTTTTGGAGGATGTTAAAAAGTTGTACCACTCAGAAGCCTTCACTGTCA
ACTTCGGGGACACCGAAGAGGCCAAGAAACAGATCAACGATTACGTGGAGAAGGGTACTCAAGGGAAAATTGTGGATTTGGTCAAGGAGC
TTGACAGAGACACAGTTTTTGCTCTGGTGAATTACATCTTCTTTAAAGGCAAATGGGAGAGACCCTTTGAAGTCAAGGACACCGAGGAAG
AGGACTTCCACGTGGACCAGGTGACCACCGTGAAGGTGCCTATGATGAAGCGTTTAGGCATGTTTAACATCCAGCACTGTAAGAAGCTGT
CCAGCTGGGTGCTGCTGATGAAATACCTGGGCAATGCCACCGCCATCTTCTTCCTGCCTGATGAGGGGAAACTACAGCACCTGGAAAATG
AACTCACCCACGATATCATCACCAAGTTCCTGGAAAATGAAGACAGAAGGTGGCACTTACTCAAAAGCATCTACTCCTAATGGTTATGAT
AATGGCATTATTTGGGCCACTTGGAAAACCCGGTGGTATTCCATGAAGAAAACCACTATGAAGATAATCCCATTCAACAGACTCACAATT
GGAGAAGGACAGCAACACCACCTGGGGGGAGCCAAACAGGTCAGACCAGAGCACCCTGCGGAAACAGAATATGACTCACTTTACCCTGAG
GATGATTTGTAGAAAATTAACTGCTAACTTCTATTGACCCACAAAGTTTCAGAAATTCTCTGAAAGTTTCTTCCTTTTTTCTCTTACTAT
ATTTATTGATTTCAAGTCTTCTATTAAGGACATTTAGCCTTCAATGGAAATTAAAACTCATTTAGGACTGTATTTCCAAATTACTGATAT

>In-frame_ENST00000449399_ENST00000407946_TCGA-FV-A23B-01A_SERPINA1_chr14_94847208_-_FGG_chr4_155526218_length(amino acids)=407AA_start in transcript=26_stop in transcript=1249
MNQEGGGGRASEEGLAAAAARNSRLEGRQPPASLQATLLCLPEETELEESLRRAGKQPPPLPLWIHCLNTDEDRALSPQLQAPPLTWDSE
STMPSSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAML
SLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAK
KQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKY

--------------------------------------------------------------
>In-frame_ENST00000402629_ENST00000336098_TCGA-FV-A23B-01A_SERPINA1_chr14_94847208_-_FGG_chr4_155526218_length(transcript)=1442nt_BP=951nt
GGCACCACCACTGACCTGGGACAGTGAATCGACAATGCCGTCTTCTGTCTCGTGGGGCATCCTCCTGCTGGCAGGCCTGTGCTGCCTGGT
CCCTGTCTCCCTGGCTGAGGATCCCCAGGGAGATGCTGCCCAGAAGACAGATACATCCCACCATGATCAGGATCACCCAACCTTCAACAA
GATCACCCCCAACCTGGCTGAGTTCGCCTTCAGCCTATACCGCCAGCTGGCACACCAGTCCAACAGCACCAATATCTTCTTCTCCCCAGT
GAGCATCGCTACAGCCTTTGCAATGCTCTCCCTGGGGACCAAGGCTGACACTCACGATGAAATCCTGGAGGGCCTGAATTTCAACCTCAC
GGAGATTCCGGAGGCTCAGATCCATGAAGGCTTCCAGGAACTCCTCCGTACCCTCAACCAGCCAGACAGCCAGCTCCAGCTGACCACCGG
CAATGGCCTGTTCCTCAGCGAGGGCCTGAAGCTAGTGGATAAGTTTTTGGAGGATGTTAAAAAGTTGTACCACTCAGAAGCCTTCACTGT
CAACTTCGGGGACACCGAAGAGGCCAAGAAACAGATCAACGATTACGTGGAGAAGGGTACTCAAGGGAAAATTGTGGATTTGGTCAAGGA
GCTTGACAGAGACACAGTTTTTGCTCTGGTGAATTACATCTTCTTTAAAGGCAAATGGGAGAGACCCTTTGAAGTCAAGGACACCGAGGA
AGAGGACTTCCACGTGGACCAGGTGACCACCGTGAAGGTGCCTATGATGAAGCGTTTAGGCATGTTTAACATCCAGCACTGTAAGAAGCT
GTCCAGCTGGGTGCTGCTGATGAAATACCTGGGCAATGCCACCGCCATCTTCTTCCTGCCTGATGAGGGGAAACTACAGCACCTGGAAAA
TGAACTCACCCACGATATCATCACCAAGTTCCTGGAAAATGAAGACAGAAGGTGGCACTTACTCAAAAGCATCTACTCCTAATGGTTATG
ATAATGGCATTATTTGGGCCACTTGGAAAACCCGGTGGTATTCCATGAAGAAAACCACTATGAAGATAATCCCATTCAACAGACTCACAA
TTGGAGAAGGACAGCAACACCACCTGGGGGGAGCCAAACAGGTCAGACCAGAGCACCCTGCGGAAACAGAATATGACTCACTTTACCCTG
AGGATGATTTGTAGAAAATTAACTGCTAACTTCTATTGACCCACAAAGTTTCAGAAATTCTCTGAAAGTTTCTTCCTTTTTTCTCTTACT
ATATTTATTGATTTCAAGTCTTCTATTAAGGACATTTAGCCTTCAATGGAAATTAAAACTCATTTAGGACTGTATTTCCAAATTACTGAT
ATCAGAGTTATTTAAAAATTGTTTATTTGAGGAGATAACATTTCAACTTTGTTCCTAAATATATAATAATAAAATGATTGACTTTATTTG

>In-frame_ENST00000402629_ENST00000336098_TCGA-FV-A23B-01A_SERPINA1_chr14_94847208_-_FGG_chr4_155526218_length(amino acids)=323AA_start in transcript=10_stop in transcript=981
MTWDSESTMPSSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIA
TAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFG
DTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSW

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SERPINA1-FGG


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SERPINA1-FGG


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SERPINA1-FGG


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneSERPINA1C0023895Liver diseases6CTD_human
HgeneSERPINA1C0086565Liver Dysfunction6CTD_human
HgeneSERPINA1C0221757alpha 1-Antitrypsin Deficiency6CTD_human;GENOMICS_ENGLAND
HgeneSERPINA1C0023890Liver Cirrhosis3CTD_human
HgeneSERPINA1C0239946Fibrosis, Liver3CTD_human
HgeneSERPINA1C0005586Bipolar Disorder2CTD_human;PSYGENET
HgeneSERPINA1C0024117Chronic Obstructive Airway Disease2CTD_human
HgeneSERPINA1C0030328Panniculitis, Nodular Nonsuppurative2CTD_human
HgeneSERPINA1C0525045Mood Disorders2PSYGENET
HgeneSERPINA1C1527303Chronic Airflow Obstruction2CTD_human
HgeneSERPINA1C2239176Liver carcinoma2CTD_human
HgeneSERPINA1C0001418Adenocarcinoma1CTD_human
HgeneSERPINA1C0003469Anxiety Disorders1CTD_human
HgeneSERPINA1C0003850Arteriosclerosis1CTD_human
HgeneSERPINA1C0003949Asbestosis1CTD_human
HgeneSERPINA1C0005587Depression, Bipolar1CTD_human
HgeneSERPINA1C0006267Bronchiectasis1CTD_human
HgeneSERPINA1C0008370Cholestasis1CTD_human
HgeneSERPINA1C0013221Drug toxicity1CTD_human
HgeneSERPINA1C0013990Pathological accumulation of air in tissues1CTD_human
HgeneSERPINA1C0019080Hemorrhage1CTD_human
HgeneSERPINA1C0019693HIV Infections1CTD_human
HgeneSERPINA1C0020615Hypoglycemia1CTD_human
HgeneSERPINA1C0022660Kidney Failure, Acute1CTD_human
HgeneSERPINA1C0024115Lung diseases1CTD_human;GENOMICS_ENGLAND
HgeneSERPINA1C0024121Lung Neoplasms1CTD_human
HgeneSERPINA1C0024623Malignant neoplasm of stomach1CTD_human
HgeneSERPINA1C0024713Manic Disorder1CTD_human
HgeneSERPINA1C0027627Neoplasm Metastasis1CTD_human
HgeneSERPINA1C0034067Pulmonary Emphysema1CTD_human
HgeneSERPINA1C0034069Pulmonary Fibrosis1CTD_human
HgeneSERPINA1C0038356Stomach Neoplasms1CTD_human
HgeneSERPINA1C0039841Thiamine Deficiency1CTD_human
HgeneSERPINA1C0041755Adverse reaction to drug1CTD_human
HgeneSERPINA1C0042384Vasculitis1CTD_human
HgeneSERPINA1C0205641Adenocarcinoma, Basal Cell1CTD_human
HgeneSERPINA1C0205642Adenocarcinoma, Oxyphilic1CTD_human
HgeneSERPINA1C0205643Carcinoma, Cribriform1CTD_human
HgeneSERPINA1C0205644Carcinoma, Granular Cell1CTD_human
HgeneSERPINA1C0205645Adenocarcinoma, Tubular1CTD_human
HgeneSERPINA1C0221227Centriacinar Emphysema1CTD_human
HgeneSERPINA1C0242379Malignant neoplasm of lung1CTD_human
HgeneSERPINA1C0264393Panacinar Emphysema1CTD_human
HgeneSERPINA1C0270715Degenerative Diseases, Central Nervous System1CTD_human
HgeneSERPINA1C0271708Fasting Hypoglycemia1CTD_human
HgeneSERPINA1C0271710Reactive hypoglycemia1CTD_human
HgeneSERPINA1C0338831Manic1CTD_human
HgeneSERPINA1C0376280Anxiety States, Neurotic1CTD_human
HgeneSERPINA1C0524851Neurodegenerative Disorders1CTD_human
HgeneSERPINA1C0751733Degenerative Diseases, Spinal Cord1CTD_human
HgeneSERPINA1C1279420Anxiety neurosis (finding)1CTD_human
HgeneSERPINA1C1565662Acute Kidney Insufficiency1CTD_human
HgeneSERPINA1C1708349Hereditary Diffuse Gastric Cancer1CTD_human
HgeneSERPINA1C2350878Focal Emphysema1CTD_human
HgeneSERPINA1C2609414Acute kidney injury1CTD_human
HgeneSERPINA1C2930617Pulmonary Fibrosis - from Asbestos Exposure1CTD_human
HgeneSERPINA1C2930967Gastro-enteropancreatic neuroendocrine tumor1CTD_human
HgeneSERPINA1C4505456HIV Coinfection1CTD_human
HgeneSERPINA1C4721507Alveolitis, Fibrosing1CTD_human
TgeneFGGC0272350Dysfibrinogenemia, Congenital6CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneFGGC2584774Congenital hypofibrinogenemia5CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneFGGC0022548Keloid1CTD_human
TgeneFGGC0024623Malignant neoplasm of stomach1CTD_human
TgeneFGGC0038356Stomach Neoplasms1CTD_human
TgeneFGGC1708349Hereditary Diffuse Gastric Cancer1CTD_human