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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:SHFM1-PALMD (FusionGDB2 ID:81105) |
Fusion Gene Summary for SHFM1-PALMD |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SHFM1-PALMD | Fusion gene ID: 81105 | Hgene | Tgene | Gene symbol | SHFM1 | PALMD | Gene ID | 7979 | 54873 |
| Gene name | SEM1 26S proteasome complex subunit | palmdelphin | |
| Synonyms | C7orf76|DSS1|ECD|SHFD1|SHFM1|SHSF1|Shfdg1 | C1orf11|PALML | |
| Cytomap | 7q21.3 | 1p21.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | 26S proteasome complex subunit SEM126S proteasome complex subunit DSS1deleted in split hand/split foot protein 1deleted in split-hand/split-foot 1split hand/foot deleted protein 1split hand/foot malformation (ectrodactyly) type 1split hand/foot malf | palmdelphinparalemmin-like proteinparalemnin-like protein | |
| Modification date | 20200322 | 20200313 | |
| UniProtAcc | . | PALMD | |
| Ensembl transtripts involved in fusion gene | ENST00000417009, ENST00000444799, ENST00000413065, ENST00000248566, ENST00000493858, | ENST00000263174, ENST00000605497, | |
| Fusion gene scores | * DoF score | 17 X 9 X 5=765 | 7 X 7 X 6=294 |
| # samples | 18 | 9 | |
| ** MAII score | log2(18/765*10)=-2.08746284125034 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(9/294*10)=-1.70781924850669 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SHFM1 [Title/Abstract] AND PALMD [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | SHFM1(96324109)-PALMD(100152231), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across SHFM1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene breakpoints across PALMD (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | OV | TCGA-09-1661 | SHFM1 | chr7 | 96324109 | - | PALMD | chr1 | 100152231 | + |
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Fusion Gene ORF analysis for SHFM1-PALMD |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000417009 | ENST00000263174 | SHFM1 | chr7 | 96324109 | - | PALMD | chr1 | 100152231 | + |
| In-frame | ENST00000417009 | ENST00000605497 | SHFM1 | chr7 | 96324109 | - | PALMD | chr1 | 100152231 | + |
| In-frame | ENST00000444799 | ENST00000263174 | SHFM1 | chr7 | 96324109 | - | PALMD | chr1 | 100152231 | + |
| In-frame | ENST00000444799 | ENST00000605497 | SHFM1 | chr7 | 96324109 | - | PALMD | chr1 | 100152231 | + |
| In-frame | ENST00000413065 | ENST00000263174 | SHFM1 | chr7 | 96324109 | - | PALMD | chr1 | 100152231 | + |
| In-frame | ENST00000413065 | ENST00000605497 | SHFM1 | chr7 | 96324109 | - | PALMD | chr1 | 100152231 | + |
| In-frame | ENST00000248566 | ENST00000263174 | SHFM1 | chr7 | 96324109 | - | PALMD | chr1 | 100152231 | + |
| In-frame | ENST00000248566 | ENST00000605497 | SHFM1 | chr7 | 96324109 | - | PALMD | chr1 | 100152231 | + |
| intron-3CDS | ENST00000493858 | ENST00000263174 | SHFM1 | chr7 | 96324109 | - | PALMD | chr1 | 100152231 | + |
| intron-3CDS | ENST00000493858 | ENST00000605497 | SHFM1 | chr7 | 96324109 | - | PALMD | chr1 | 100152231 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000417009 | SHFM1 | chr7 | 96324109 | - | ENST00000263174 | PALMD | chr1 | 100152231 | + | 2152 | 268 | 98 | 1672 | 524 |
| ENST00000417009 | SHFM1 | chr7 | 96324109 | - | ENST00000605497 | PALMD | chr1 | 100152231 | + | 1834 | 268 | 98 | 1672 | 524 |
| ENST00000444799 | SHFM1 | chr7 | 96324109 | - | ENST00000263174 | PALMD | chr1 | 100152231 | + | 2149 | 265 | 95 | 1669 | 524 |
| ENST00000444799 | SHFM1 | chr7 | 96324109 | - | ENST00000605497 | PALMD | chr1 | 100152231 | + | 1831 | 265 | 95 | 1669 | 524 |
| ENST00000413065 | SHFM1 | chr7 | 96324109 | - | ENST00000263174 | PALMD | chr1 | 100152231 | + | 2142 | 258 | 88 | 1662 | 524 |
| ENST00000413065 | SHFM1 | chr7 | 96324109 | - | ENST00000605497 | PALMD | chr1 | 100152231 | + | 1824 | 258 | 88 | 1662 | 524 |
| ENST00000248566 | SHFM1 | chr7 | 96324109 | - | ENST00000263174 | PALMD | chr1 | 100152231 | + | 2182 | 298 | 128 | 1702 | 524 |
| ENST00000248566 | SHFM1 | chr7 | 96324109 | - | ENST00000605497 | PALMD | chr1 | 100152231 | + | 1864 | 298 | 128 | 1702 | 524 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000417009 | ENST00000263174 | SHFM1 | chr7 | 96324109 | - | PALMD | chr1 | 100152231 | + | 0.000601052 | 0.99939895 |
| ENST00000417009 | ENST00000605497 | SHFM1 | chr7 | 96324109 | - | PALMD | chr1 | 100152231 | + | 0.000836487 | 0.9991635 |
| ENST00000444799 | ENST00000263174 | SHFM1 | chr7 | 96324109 | - | PALMD | chr1 | 100152231 | + | 0.000583752 | 0.99941623 |
| ENST00000444799 | ENST00000605497 | SHFM1 | chr7 | 96324109 | - | PALMD | chr1 | 100152231 | + | 0.000815964 | 0.9991841 |
| ENST00000413065 | ENST00000263174 | SHFM1 | chr7 | 96324109 | - | PALMD | chr1 | 100152231 | + | 0.00058462 | 0.9994154 |
| ENST00000413065 | ENST00000605497 | SHFM1 | chr7 | 96324109 | - | PALMD | chr1 | 100152231 | + | 0.000815189 | 0.9991848 |
| ENST00000248566 | ENST00000263174 | SHFM1 | chr7 | 96324109 | - | PALMD | chr1 | 100152231 | + | 0.000580664 | 0.99941933 |
| ENST00000248566 | ENST00000605497 | SHFM1 | chr7 | 96324109 | - | PALMD | chr1 | 100152231 | + | 0.000797322 | 0.99920267 |
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Fusion Genomic Features for SHFM1-PALMD |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| SHFM1 | chr7 | 96324109 | - | PALMD | chr1 | 100152231 | + | 1.84E-07 | 0.99999976 |
| SHFM1 | chr7 | 96324109 | - | PALMD | chr1 | 100152231 | + | 1.84E-07 | 0.99999976 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for SHFM1-PALMD |
| Go to FGviewer for the breakpoints of chr7:96324109-chr1:100152231 - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | PALMD |
| FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes. | 551 |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SHFM1 | chr7:96324109 | chr1:100152231 | ENST00000248566 | - | 2 | 3 | 14_21 | 56.666666666666664 | 71.0 | Compositional bias | Note=Asp/Glu-rich (highly acidic) |
| Hgene | SHFM1 | chr7:96324109 | chr1:100152231 | ENST00000248566 | - | 2 | 3 | 31_35 | 56.666666666666664 | 71.0 | Compositional bias | Note=Asp/Glu-rich (highly acidic) |
| Hgene | SHFM1 | chr7:96324109 | chr1:100152231 | ENST00000248566 | - | 2 | 3 | 40_51 | 56.666666666666664 | 71.0 | Compositional bias | Note=Asp/Glu-rich (highly acidic) |
| Tgene | PALMD | chr7:96324109 | chr1:100152231 | ENST00000263174 | 2 | 8 | 450_459 | 83.66666666666667 | 552.0 | Compositional bias | Note=Poly-Glu |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | PALMD | chr7:96324109 | chr1:100152231 | ENST00000263174 | 2 | 8 | 12_106 | 83.66666666666667 | 552.0 | Coiled coil | Ontology_term=ECO:0000255 |
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Fusion Gene Sequence for SHFM1-PALMD |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >In-frame_ENST00000417009_ENST00000263174_TCGA-09-1661_SHFM1_chr7_96324109_-_PALMD_chr1_100152231_length(transcript)=2152nt_BP=268nt AGCGTCGGAGGCGGTAGTGACGGTGGCGTTTCCTTGAGGAAGAGTGAGGGTTCCAACTTTTCTGCTTATCTGGGAGGTGTTGGGCGCGGA CAGTCGAGATGTCAGAGAAAAAGCAGCCGGTAGACTTAGGTCTGTTAGAGGAAGACGACGAGTTTGAAGAGTTCCCTGCCGAAGACTGGG CTGGCTTAGATGAAGATGAAGATGCACATGTCTGGGAGGATAATTGGGATGATGACAATGTAGAGGATGACTTCTCTAATCAGTTACGGC TTGAGAAAGAGATCCAAGATCTTGAAAAAGCTGAACTGCAAATCTCAACGAAGGAAGAGGCCATTTTAAAGAAACTAAAGTCAATTGAGC GGACAACAGAAGACATTATAAGATCTGTGAAAGTGGAAAGAGAAGAAAGAGCAGAAGAGTCAATTGAGGACATCTATGCTAATATCCCTG ACCTTCCAAAGTCCTACATACCTTCTAGGTTAAGGAAGGAGATAAATGAAGAAAAAGAAGATGATGAACAAAATAGGAAAGCTTTATATG CCATGGAAATTAAAGTTGAAAAAGACTTGAAGACTGGAGAAAGTACAGTTCTGTCTTCAATACCTCTGCCATCAGATGACTTTAAAGGTA CAGGAATAAAAGTTTATGATGATGGGCAAAAGTCAGTGTATGCAGTAAGTTCTAATCACAGTGCAGCATACAATGGCACCGATGGCCTGG CACCAGTTGAAGTAGAGGAACTTCTAAGACAAGCCTCAGAGAGAAACTCTAAATCCCCAACAGAGTATCATGAGCCTGTATATGCCAATC CCTTTTACAGGCCTACAACCCCACAGAGAGAAACGGTGACCCCTGGACCAAACTTTCAAGAAAGGATAAAGATTAAAACTAATGGACTGG GTATTGGTGTAAATGAATCCATACACAATATGGGCAATGGTCTTTCAGAGGAAAGGGGAAACAACTTCAATCACATCAGTCCCATTCCGC CAGTGCCTCATCCCCGATCAGTGATTCAACAAGCAGAAGAGAAGCTTCACACCCCGCAAAAAAGGCTAATGACTCCTTGGGAAGAATCGA ATGTCATGCAGGACAAAGATGCACCCTCTCCAAAGCCAAGGCTGAGCCCCAGAGAGACAATATTTGGGAAATCTGAACACCAGAATTCTT CACCCACTTGTCAGGAGGACGAGGAAGATGTCAGATATAATATCGTTCATTCCCTGCCTCCAGACATAAATGATACAGAACCGGTGACAA TGATTTTCATGGGGTATCAGCAGGCAGAAGACAGTGAAGAAGATAAGAAGTTTCTGACAGGATATGATGGGATCATCCATGCTGAGCTGG TTGTGATTGATGATGAGGAGGAGGAGGATGAAGGAGAAGCAGAGAAACCGTCCTACCACCCCATAGCTCCCCATAGTCAGGTGTACCAGC CAGCCAAACCAACACCACTTCCTAGAAAAAGATCAGAAGCTAGTCCTCATGAAAACACAAATCATAAATCCCCCCACAAAAATTCCATAT CTCTGAAAGAGCAAGAAGAAAGCTTAGGCAGCCCTGTCCACCATTCCCCATTTGATGCTCAGACAACTGGAGATGGGACTGAGGATCCAT CCTTAACAGCTTTAAGGATGAGAATGGCAAAGCTGGGAAAAAAGGTGATCTAAGAGTTGTACCACCTATATAAACATCCTTTGAAGAAGA AACTAAGAAGCATTTGCAAATTTCTCTTCTGGATATTTTGTTTATTTTTTCTGAAGTCCAAAAAATTATCATTACAGTGTACCATATTAA GCCATGTGAATAAGTAGTAGTCATTATTTGTGAAAAATTCCCAAAAAGCTGGGGAAAACAAATGTGTAACTTTTCCAGTTACTTGACACG ATTCAGTGGGGGAAAACCAGCATTTTTTATTCTATTGATACCAAAGCATTTCTAATAAGAGCTTGTTAAATTTAAGAATAAAGTTATTTA AAATATTCTGAGTATAGTATATTAACTGGCATTGTAATTTTGATGATACAAAGATTGAAAGATCATAGGAAAGCATTGCCCTTCATCACA >In-frame_ENST00000417009_ENST00000263174_TCGA-09-1661_SHFM1_chr7_96324109_-_PALMD_chr1_100152231_length(amino acids)=524AA_start in transcript=98_stop in transcript=1672 MSEKKQPVDLGLLEEDDEFEEFPAEDWAGLDEDEDAHVWEDNWDDDNVEDDFSNQLRLEKEIQDLEKAELQISTKEEAILKKLKSIERTT EDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIKVEKDLKTGESTVLSSIPLPSDDFKGTGI KVYDDGQKSVYAVSSNHSAAYNGTDGLAPVEVEELLRQASERNSKSPTEYHEPVYANPFYRPTTPQRETVTPGPNFQERIKIKTNGLGIG VNESIHNMGNGLSEERGNNFNHISPIPPVPHPRSVIQQAEEKLHTPQKRLMTPWEESNVMQDKDAPSPKPRLSPRETIFGKSEHQNSSPT CQEDEEDVRYNIVHSLPPDINDTEPVTMIFMGYQQAEDSEEDKKFLTGYDGIIHAELVVIDDEEEEDEGEAEKPSYHPIAPHSQVYQPAK -------------------------------------------------------------- >In-frame_ENST00000417009_ENST00000605497_TCGA-09-1661_SHFM1_chr7_96324109_-_PALMD_chr1_100152231_length(transcript)=1834nt_BP=268nt AGCGTCGGAGGCGGTAGTGACGGTGGCGTTTCCTTGAGGAAGAGTGAGGGTTCCAACTTTTCTGCTTATCTGGGAGGTGTTGGGCGCGGA CAGTCGAGATGTCAGAGAAAAAGCAGCCGGTAGACTTAGGTCTGTTAGAGGAAGACGACGAGTTTGAAGAGTTCCCTGCCGAAGACTGGG CTGGCTTAGATGAAGATGAAGATGCACATGTCTGGGAGGATAATTGGGATGATGACAATGTAGAGGATGACTTCTCTAATCAGTTACGGC TTGAGAAAGAGATCCAAGATCTTGAAAAAGCTGAACTGCAAATCTCAACGAAGGAAGAGGCCATTTTAAAGAAACTAAAGTCAATTGAGC GGACAACAGAAGACATTATAAGATCTGTGAAAGTGGAAAGAGAAGAAAGAGCAGAAGAGTCAATTGAGGACATCTATGCTAATATCCCTG ACCTTCCAAAGTCCTACATACCTTCTAGGTTAAGGAAGGAGATAAATGAAGAAAAAGAAGATGATGAACAAAATAGGAAAGCTTTATATG CCATGGAAATTAAAGTTGAAAAAGACTTGAAGACTGGAGAAAGTACAGTTCTGTCTTCAATACCTCTGCCATCAGATGACTTTAAAGGTA CAGGAATAAAAGTTTATGATGATGGGCAAAAGTCAGTGTATGCAGTAAGTTCTAATCACAGTGCAGCATACAATGGCACCGATGGCCTGG CACCAGTTGAAGTAGAGGAACTTCTAAGACAAGCCTCAGAGAGAAACTCTAAATCCCCAACAGAGTATCATGAGCCTGTATATGCCAATC CCTTTTACAGGCCTACAACCCCACAGAGAGAAACGGTGACCCCTGGACCAAACTTTCAAGAAAGGATAAAGATTAAAACTAATGGACTGG GTATTGGTGTAAATGAATCCATACACAATATGGGCAATGGTCTTTCAGAGGAAAGGGGAAACAACTTCAATCACATCAGTCCCATTCCGC CAGTGCCTCATCCCCGATCAGTGATTCAACAAGCAGAAGAGAAGCTTCACACCCCGCAAAAAAGGCTAATGACTCCTTGGGAAGAATCGA ATGTCATGCAGGACAAAGATGCACCCTCTCCAAAGCCAAGGCTGAGCCCCAGAGAGACAATATTTGGGAAATCTGAACACCAGAATTCTT CACCCACTTGTCAGGAGGACGAGGAAGATGTCAGATATAATATCGTTCATTCCCTGCCTCCAGACATAAATGATACAGAACCGGTGACAA TGATTTTCATGGGGTATCAGCAGGCAGAAGACAGTGAAGAAGATAAGAAGTTTCTGACAGGATATGATGGGATCATCCATGCTGAGCTGG TTGTGATTGATGATGAGGAGGAGGAGGATGAAGGAGAAGCAGAGAAACCGTCCTACCACCCCATAGCTCCCCATAGTCAGGTGTACCAGC CAGCCAAACCAACACCACTTCCTAGAAAAAGATCAGAAGCTAGTCCTCATGAAAACACAAATCATAAATCCCCCCACAAAAATTCCATAT CTCTGAAAGAGCAAGAAGAAAGCTTAGGCAGCCCTGTCCACCATTCCCCATTTGATGCTCAGACAACTGGAGATGGGACTGAGGATCCAT CCTTAACAGGTAATAAAAATGACAAGGCATGCCACTGCTGTTCAGTCATGTGACCAGCTTCTCTTGTGCTAATGCAGTCTTGCTTTCAGG CTTCTCTGACCACCTCATAAACTAATACGCACTGAGATTTTTTTATTAATGCTGATAGAGATTATTATCACCACAGTAAAGTGATTAAGT >In-frame_ENST00000417009_ENST00000605497_TCGA-09-1661_SHFM1_chr7_96324109_-_PALMD_chr1_100152231_length(amino acids)=524AA_start in transcript=98_stop in transcript=1672 MSEKKQPVDLGLLEEDDEFEEFPAEDWAGLDEDEDAHVWEDNWDDDNVEDDFSNQLRLEKEIQDLEKAELQISTKEEAILKKLKSIERTT EDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIKVEKDLKTGESTVLSSIPLPSDDFKGTGI KVYDDGQKSVYAVSSNHSAAYNGTDGLAPVEVEELLRQASERNSKSPTEYHEPVYANPFYRPTTPQRETVTPGPNFQERIKIKTNGLGIG VNESIHNMGNGLSEERGNNFNHISPIPPVPHPRSVIQQAEEKLHTPQKRLMTPWEESNVMQDKDAPSPKPRLSPRETIFGKSEHQNSSPT CQEDEEDVRYNIVHSLPPDINDTEPVTMIFMGYQQAEDSEEDKKFLTGYDGIIHAELVVIDDEEEEDEGEAEKPSYHPIAPHSQVYQPAK -------------------------------------------------------------- >In-frame_ENST00000444799_ENST00000263174_TCGA-09-1661_SHFM1_chr7_96324109_-_PALMD_chr1_100152231_length(transcript)=2149nt_BP=265nt GTCGGAGGCGGTAGTGACGGTGGCGTTTCCTTGAGGAAGAGTGAGGGTTCCAACTTTTCTGCTTATCTGGGAGGTGTTGGGCGCGGACAG TCGAGATGTCAGAGAAAAAGCAGCCGGTAGACTTAGGTCTGTTAGAGGAAGACGACGAGTTTGAAGAGTTCCCTGCCGAAGACTGGGCTG GCTTAGATGAAGATGAAGATGCACATGTCTGGGAGGATAATTGGGATGATGACAATGTAGAGGATGACTTCTCTAATCAGTTACGGCTTG AGAAAGAGATCCAAGATCTTGAAAAAGCTGAACTGCAAATCTCAACGAAGGAAGAGGCCATTTTAAAGAAACTAAAGTCAATTGAGCGGA CAACAGAAGACATTATAAGATCTGTGAAAGTGGAAAGAGAAGAAAGAGCAGAAGAGTCAATTGAGGACATCTATGCTAATATCCCTGACC TTCCAAAGTCCTACATACCTTCTAGGTTAAGGAAGGAGATAAATGAAGAAAAAGAAGATGATGAACAAAATAGGAAAGCTTTATATGCCA TGGAAATTAAAGTTGAAAAAGACTTGAAGACTGGAGAAAGTACAGTTCTGTCTTCAATACCTCTGCCATCAGATGACTTTAAAGGTACAG GAATAAAAGTTTATGATGATGGGCAAAAGTCAGTGTATGCAGTAAGTTCTAATCACAGTGCAGCATACAATGGCACCGATGGCCTGGCAC CAGTTGAAGTAGAGGAACTTCTAAGACAAGCCTCAGAGAGAAACTCTAAATCCCCAACAGAGTATCATGAGCCTGTATATGCCAATCCCT TTTACAGGCCTACAACCCCACAGAGAGAAACGGTGACCCCTGGACCAAACTTTCAAGAAAGGATAAAGATTAAAACTAATGGACTGGGTA TTGGTGTAAATGAATCCATACACAATATGGGCAATGGTCTTTCAGAGGAAAGGGGAAACAACTTCAATCACATCAGTCCCATTCCGCCAG TGCCTCATCCCCGATCAGTGATTCAACAAGCAGAAGAGAAGCTTCACACCCCGCAAAAAAGGCTAATGACTCCTTGGGAAGAATCGAATG TCATGCAGGACAAAGATGCACCCTCTCCAAAGCCAAGGCTGAGCCCCAGAGAGACAATATTTGGGAAATCTGAACACCAGAATTCTTCAC CCACTTGTCAGGAGGACGAGGAAGATGTCAGATATAATATCGTTCATTCCCTGCCTCCAGACATAAATGATACAGAACCGGTGACAATGA TTTTCATGGGGTATCAGCAGGCAGAAGACAGTGAAGAAGATAAGAAGTTTCTGACAGGATATGATGGGATCATCCATGCTGAGCTGGTTG TGATTGATGATGAGGAGGAGGAGGATGAAGGAGAAGCAGAGAAACCGTCCTACCACCCCATAGCTCCCCATAGTCAGGTGTACCAGCCAG CCAAACCAACACCACTTCCTAGAAAAAGATCAGAAGCTAGTCCTCATGAAAACACAAATCATAAATCCCCCCACAAAAATTCCATATCTC TGAAAGAGCAAGAAGAAAGCTTAGGCAGCCCTGTCCACCATTCCCCATTTGATGCTCAGACAACTGGAGATGGGACTGAGGATCCATCCT TAACAGCTTTAAGGATGAGAATGGCAAAGCTGGGAAAAAAGGTGATCTAAGAGTTGTACCACCTATATAAACATCCTTTGAAGAAGAAAC TAAGAAGCATTTGCAAATTTCTCTTCTGGATATTTTGTTTATTTTTTCTGAAGTCCAAAAAATTATCATTACAGTGTACCATATTAAGCC ATGTGAATAAGTAGTAGTCATTATTTGTGAAAAATTCCCAAAAAGCTGGGGAAAACAAATGTGTAACTTTTCCAGTTACTTGACACGATT CAGTGGGGGAAAACCAGCATTTTTTATTCTATTGATACCAAAGCATTTCTAATAAGAGCTTGTTAAATTTAAGAATAAAGTTATTTAAAA TATTCTGAGTATAGTATATTAACTGGCATTGTAATTTTGATGATACAAAGATTGAAAGATCATAGGAAAGCATTGCCCTTCATCACAGAA >In-frame_ENST00000444799_ENST00000263174_TCGA-09-1661_SHFM1_chr7_96324109_-_PALMD_chr1_100152231_length(amino acids)=524AA_start in transcript=95_stop in transcript=1669 MSEKKQPVDLGLLEEDDEFEEFPAEDWAGLDEDEDAHVWEDNWDDDNVEDDFSNQLRLEKEIQDLEKAELQISTKEEAILKKLKSIERTT EDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIKVEKDLKTGESTVLSSIPLPSDDFKGTGI KVYDDGQKSVYAVSSNHSAAYNGTDGLAPVEVEELLRQASERNSKSPTEYHEPVYANPFYRPTTPQRETVTPGPNFQERIKIKTNGLGIG VNESIHNMGNGLSEERGNNFNHISPIPPVPHPRSVIQQAEEKLHTPQKRLMTPWEESNVMQDKDAPSPKPRLSPRETIFGKSEHQNSSPT CQEDEEDVRYNIVHSLPPDINDTEPVTMIFMGYQQAEDSEEDKKFLTGYDGIIHAELVVIDDEEEEDEGEAEKPSYHPIAPHSQVYQPAK -------------------------------------------------------------- >In-frame_ENST00000444799_ENST00000605497_TCGA-09-1661_SHFM1_chr7_96324109_-_PALMD_chr1_100152231_length(transcript)=1831nt_BP=265nt GTCGGAGGCGGTAGTGACGGTGGCGTTTCCTTGAGGAAGAGTGAGGGTTCCAACTTTTCTGCTTATCTGGGAGGTGTTGGGCGCGGACAG TCGAGATGTCAGAGAAAAAGCAGCCGGTAGACTTAGGTCTGTTAGAGGAAGACGACGAGTTTGAAGAGTTCCCTGCCGAAGACTGGGCTG GCTTAGATGAAGATGAAGATGCACATGTCTGGGAGGATAATTGGGATGATGACAATGTAGAGGATGACTTCTCTAATCAGTTACGGCTTG AGAAAGAGATCCAAGATCTTGAAAAAGCTGAACTGCAAATCTCAACGAAGGAAGAGGCCATTTTAAAGAAACTAAAGTCAATTGAGCGGA CAACAGAAGACATTATAAGATCTGTGAAAGTGGAAAGAGAAGAAAGAGCAGAAGAGTCAATTGAGGACATCTATGCTAATATCCCTGACC TTCCAAAGTCCTACATACCTTCTAGGTTAAGGAAGGAGATAAATGAAGAAAAAGAAGATGATGAACAAAATAGGAAAGCTTTATATGCCA TGGAAATTAAAGTTGAAAAAGACTTGAAGACTGGAGAAAGTACAGTTCTGTCTTCAATACCTCTGCCATCAGATGACTTTAAAGGTACAG GAATAAAAGTTTATGATGATGGGCAAAAGTCAGTGTATGCAGTAAGTTCTAATCACAGTGCAGCATACAATGGCACCGATGGCCTGGCAC CAGTTGAAGTAGAGGAACTTCTAAGACAAGCCTCAGAGAGAAACTCTAAATCCCCAACAGAGTATCATGAGCCTGTATATGCCAATCCCT TTTACAGGCCTACAACCCCACAGAGAGAAACGGTGACCCCTGGACCAAACTTTCAAGAAAGGATAAAGATTAAAACTAATGGACTGGGTA TTGGTGTAAATGAATCCATACACAATATGGGCAATGGTCTTTCAGAGGAAAGGGGAAACAACTTCAATCACATCAGTCCCATTCCGCCAG TGCCTCATCCCCGATCAGTGATTCAACAAGCAGAAGAGAAGCTTCACACCCCGCAAAAAAGGCTAATGACTCCTTGGGAAGAATCGAATG TCATGCAGGACAAAGATGCACCCTCTCCAAAGCCAAGGCTGAGCCCCAGAGAGACAATATTTGGGAAATCTGAACACCAGAATTCTTCAC CCACTTGTCAGGAGGACGAGGAAGATGTCAGATATAATATCGTTCATTCCCTGCCTCCAGACATAAATGATACAGAACCGGTGACAATGA TTTTCATGGGGTATCAGCAGGCAGAAGACAGTGAAGAAGATAAGAAGTTTCTGACAGGATATGATGGGATCATCCATGCTGAGCTGGTTG TGATTGATGATGAGGAGGAGGAGGATGAAGGAGAAGCAGAGAAACCGTCCTACCACCCCATAGCTCCCCATAGTCAGGTGTACCAGCCAG CCAAACCAACACCACTTCCTAGAAAAAGATCAGAAGCTAGTCCTCATGAAAACACAAATCATAAATCCCCCCACAAAAATTCCATATCTC TGAAAGAGCAAGAAGAAAGCTTAGGCAGCCCTGTCCACCATTCCCCATTTGATGCTCAGACAACTGGAGATGGGACTGAGGATCCATCCT TAACAGGTAATAAAAATGACAAGGCATGCCACTGCTGTTCAGTCATGTGACCAGCTTCTCTTGTGCTAATGCAGTCTTGCTTTCAGGCTT CTCTGACCACCTCATAAACTAATACGCACTGAGATTTTTTTATTAATGCTGATAGAGATTATTATCACCACAGTAAAGTGATTAAGTCAC >In-frame_ENST00000444799_ENST00000605497_TCGA-09-1661_SHFM1_chr7_96324109_-_PALMD_chr1_100152231_length(amino acids)=524AA_start in transcript=95_stop in transcript=1669 MSEKKQPVDLGLLEEDDEFEEFPAEDWAGLDEDEDAHVWEDNWDDDNVEDDFSNQLRLEKEIQDLEKAELQISTKEEAILKKLKSIERTT EDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIKVEKDLKTGESTVLSSIPLPSDDFKGTGI KVYDDGQKSVYAVSSNHSAAYNGTDGLAPVEVEELLRQASERNSKSPTEYHEPVYANPFYRPTTPQRETVTPGPNFQERIKIKTNGLGIG VNESIHNMGNGLSEERGNNFNHISPIPPVPHPRSVIQQAEEKLHTPQKRLMTPWEESNVMQDKDAPSPKPRLSPRETIFGKSEHQNSSPT CQEDEEDVRYNIVHSLPPDINDTEPVTMIFMGYQQAEDSEEDKKFLTGYDGIIHAELVVIDDEEEEDEGEAEKPSYHPIAPHSQVYQPAK -------------------------------------------------------------- >In-frame_ENST00000413065_ENST00000263174_TCGA-09-1661_SHFM1_chr7_96324109_-_PALMD_chr1_100152231_length(transcript)=2142nt_BP=258nt GCGGTAGTGACGGTGGCGTTTCCTTGAGGAAGAGTGAGGGTTCCAACTTTTCTGCTTATCTGGGAGGTGTTGGGCGCGGACAGTCGAGAT GTCAGAGAAAAAGCAGCCGGTAGACTTAGGTCTGTTAGAGGAAGACGACGAGTTTGAAGAGTTCCCTGCCGAAGACTGGGCTGGCTTAGA TGAAGATGAAGATGCACATGTCTGGGAGGATAATTGGGATGATGACAATGTAGAGGATGACTTCTCTAATCAGTTACGGCTTGAGAAAGA GATCCAAGATCTTGAAAAAGCTGAACTGCAAATCTCAACGAAGGAAGAGGCCATTTTAAAGAAACTAAAGTCAATTGAGCGGACAACAGA AGACATTATAAGATCTGTGAAAGTGGAAAGAGAAGAAAGAGCAGAAGAGTCAATTGAGGACATCTATGCTAATATCCCTGACCTTCCAAA GTCCTACATACCTTCTAGGTTAAGGAAGGAGATAAATGAAGAAAAAGAAGATGATGAACAAAATAGGAAAGCTTTATATGCCATGGAAAT TAAAGTTGAAAAAGACTTGAAGACTGGAGAAAGTACAGTTCTGTCTTCAATACCTCTGCCATCAGATGACTTTAAAGGTACAGGAATAAA AGTTTATGATGATGGGCAAAAGTCAGTGTATGCAGTAAGTTCTAATCACAGTGCAGCATACAATGGCACCGATGGCCTGGCACCAGTTGA AGTAGAGGAACTTCTAAGACAAGCCTCAGAGAGAAACTCTAAATCCCCAACAGAGTATCATGAGCCTGTATATGCCAATCCCTTTTACAG GCCTACAACCCCACAGAGAGAAACGGTGACCCCTGGACCAAACTTTCAAGAAAGGATAAAGATTAAAACTAATGGACTGGGTATTGGTGT AAATGAATCCATACACAATATGGGCAATGGTCTTTCAGAGGAAAGGGGAAACAACTTCAATCACATCAGTCCCATTCCGCCAGTGCCTCA TCCCCGATCAGTGATTCAACAAGCAGAAGAGAAGCTTCACACCCCGCAAAAAAGGCTAATGACTCCTTGGGAAGAATCGAATGTCATGCA GGACAAAGATGCACCCTCTCCAAAGCCAAGGCTGAGCCCCAGAGAGACAATATTTGGGAAATCTGAACACCAGAATTCTTCACCCACTTG TCAGGAGGACGAGGAAGATGTCAGATATAATATCGTTCATTCCCTGCCTCCAGACATAAATGATACAGAACCGGTGACAATGATTTTCAT GGGGTATCAGCAGGCAGAAGACAGTGAAGAAGATAAGAAGTTTCTGACAGGATATGATGGGATCATCCATGCTGAGCTGGTTGTGATTGA TGATGAGGAGGAGGAGGATGAAGGAGAAGCAGAGAAACCGTCCTACCACCCCATAGCTCCCCATAGTCAGGTGTACCAGCCAGCCAAACC AACACCACTTCCTAGAAAAAGATCAGAAGCTAGTCCTCATGAAAACACAAATCATAAATCCCCCCACAAAAATTCCATATCTCTGAAAGA GCAAGAAGAAAGCTTAGGCAGCCCTGTCCACCATTCCCCATTTGATGCTCAGACAACTGGAGATGGGACTGAGGATCCATCCTTAACAGC TTTAAGGATGAGAATGGCAAAGCTGGGAAAAAAGGTGATCTAAGAGTTGTACCACCTATATAAACATCCTTTGAAGAAGAAACTAAGAAG CATTTGCAAATTTCTCTTCTGGATATTTTGTTTATTTTTTCTGAAGTCCAAAAAATTATCATTACAGTGTACCATATTAAGCCATGTGAA TAAGTAGTAGTCATTATTTGTGAAAAATTCCCAAAAAGCTGGGGAAAACAAATGTGTAACTTTTCCAGTTACTTGACACGATTCAGTGGG GGAAAACCAGCATTTTTTATTCTATTGATACCAAAGCATTTCTAATAAGAGCTTGTTAAATTTAAGAATAAAGTTATTTAAAATATTCTG AGTATAGTATATTAACTGGCATTGTAATTTTGATGATACAAAGATTGAAAGATCATAGGAAAGCATTGCCCTTCATCACAGAAGTATTCA >In-frame_ENST00000413065_ENST00000263174_TCGA-09-1661_SHFM1_chr7_96324109_-_PALMD_chr1_100152231_length(amino acids)=524AA_start in transcript=88_stop in transcript=1662 MSEKKQPVDLGLLEEDDEFEEFPAEDWAGLDEDEDAHVWEDNWDDDNVEDDFSNQLRLEKEIQDLEKAELQISTKEEAILKKLKSIERTT EDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIKVEKDLKTGESTVLSSIPLPSDDFKGTGI KVYDDGQKSVYAVSSNHSAAYNGTDGLAPVEVEELLRQASERNSKSPTEYHEPVYANPFYRPTTPQRETVTPGPNFQERIKIKTNGLGIG VNESIHNMGNGLSEERGNNFNHISPIPPVPHPRSVIQQAEEKLHTPQKRLMTPWEESNVMQDKDAPSPKPRLSPRETIFGKSEHQNSSPT CQEDEEDVRYNIVHSLPPDINDTEPVTMIFMGYQQAEDSEEDKKFLTGYDGIIHAELVVIDDEEEEDEGEAEKPSYHPIAPHSQVYQPAK -------------------------------------------------------------- >In-frame_ENST00000413065_ENST00000605497_TCGA-09-1661_SHFM1_chr7_96324109_-_PALMD_chr1_100152231_length(transcript)=1824nt_BP=258nt GCGGTAGTGACGGTGGCGTTTCCTTGAGGAAGAGTGAGGGTTCCAACTTTTCTGCTTATCTGGGAGGTGTTGGGCGCGGACAGTCGAGAT GTCAGAGAAAAAGCAGCCGGTAGACTTAGGTCTGTTAGAGGAAGACGACGAGTTTGAAGAGTTCCCTGCCGAAGACTGGGCTGGCTTAGA TGAAGATGAAGATGCACATGTCTGGGAGGATAATTGGGATGATGACAATGTAGAGGATGACTTCTCTAATCAGTTACGGCTTGAGAAAGA GATCCAAGATCTTGAAAAAGCTGAACTGCAAATCTCAACGAAGGAAGAGGCCATTTTAAAGAAACTAAAGTCAATTGAGCGGACAACAGA AGACATTATAAGATCTGTGAAAGTGGAAAGAGAAGAAAGAGCAGAAGAGTCAATTGAGGACATCTATGCTAATATCCCTGACCTTCCAAA GTCCTACATACCTTCTAGGTTAAGGAAGGAGATAAATGAAGAAAAAGAAGATGATGAACAAAATAGGAAAGCTTTATATGCCATGGAAAT TAAAGTTGAAAAAGACTTGAAGACTGGAGAAAGTACAGTTCTGTCTTCAATACCTCTGCCATCAGATGACTTTAAAGGTACAGGAATAAA AGTTTATGATGATGGGCAAAAGTCAGTGTATGCAGTAAGTTCTAATCACAGTGCAGCATACAATGGCACCGATGGCCTGGCACCAGTTGA AGTAGAGGAACTTCTAAGACAAGCCTCAGAGAGAAACTCTAAATCCCCAACAGAGTATCATGAGCCTGTATATGCCAATCCCTTTTACAG GCCTACAACCCCACAGAGAGAAACGGTGACCCCTGGACCAAACTTTCAAGAAAGGATAAAGATTAAAACTAATGGACTGGGTATTGGTGT AAATGAATCCATACACAATATGGGCAATGGTCTTTCAGAGGAAAGGGGAAACAACTTCAATCACATCAGTCCCATTCCGCCAGTGCCTCA TCCCCGATCAGTGATTCAACAAGCAGAAGAGAAGCTTCACACCCCGCAAAAAAGGCTAATGACTCCTTGGGAAGAATCGAATGTCATGCA GGACAAAGATGCACCCTCTCCAAAGCCAAGGCTGAGCCCCAGAGAGACAATATTTGGGAAATCTGAACACCAGAATTCTTCACCCACTTG TCAGGAGGACGAGGAAGATGTCAGATATAATATCGTTCATTCCCTGCCTCCAGACATAAATGATACAGAACCGGTGACAATGATTTTCAT GGGGTATCAGCAGGCAGAAGACAGTGAAGAAGATAAGAAGTTTCTGACAGGATATGATGGGATCATCCATGCTGAGCTGGTTGTGATTGA TGATGAGGAGGAGGAGGATGAAGGAGAAGCAGAGAAACCGTCCTACCACCCCATAGCTCCCCATAGTCAGGTGTACCAGCCAGCCAAACC AACACCACTTCCTAGAAAAAGATCAGAAGCTAGTCCTCATGAAAACACAAATCATAAATCCCCCCACAAAAATTCCATATCTCTGAAAGA GCAAGAAGAAAGCTTAGGCAGCCCTGTCCACCATTCCCCATTTGATGCTCAGACAACTGGAGATGGGACTGAGGATCCATCCTTAACAGG TAATAAAAATGACAAGGCATGCCACTGCTGTTCAGTCATGTGACCAGCTTCTCTTGTGCTAATGCAGTCTTGCTTTCAGGCTTCTCTGAC CACCTCATAAACTAATACGCACTGAGATTTTTTTATTAATGCTGATAGAGATTATTATCACCACAGTAAAGTGATTAAGTCACTTCAAAA >In-frame_ENST00000413065_ENST00000605497_TCGA-09-1661_SHFM1_chr7_96324109_-_PALMD_chr1_100152231_length(amino acids)=524AA_start in transcript=88_stop in transcript=1662 MSEKKQPVDLGLLEEDDEFEEFPAEDWAGLDEDEDAHVWEDNWDDDNVEDDFSNQLRLEKEIQDLEKAELQISTKEEAILKKLKSIERTT EDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIKVEKDLKTGESTVLSSIPLPSDDFKGTGI KVYDDGQKSVYAVSSNHSAAYNGTDGLAPVEVEELLRQASERNSKSPTEYHEPVYANPFYRPTTPQRETVTPGPNFQERIKIKTNGLGIG VNESIHNMGNGLSEERGNNFNHISPIPPVPHPRSVIQQAEEKLHTPQKRLMTPWEESNVMQDKDAPSPKPRLSPRETIFGKSEHQNSSPT CQEDEEDVRYNIVHSLPPDINDTEPVTMIFMGYQQAEDSEEDKKFLTGYDGIIHAELVVIDDEEEEDEGEAEKPSYHPIAPHSQVYQPAK -------------------------------------------------------------- >In-frame_ENST00000248566_ENST00000263174_TCGA-09-1661_SHFM1_chr7_96324109_-_PALMD_chr1_100152231_length(transcript)=2182nt_BP=298nt ATTCTTTCCCCAAGTCTCTATGGTAGCGTCAGCGTCGGAGGCGGTAGTGACGGTGGCGTTTCCTTGAGGAAGAGTGAGGGTTCCAACTTT TCTGCTTATCTGGGAGGTGTTGGGCGCGGACAGTCGAGATGTCAGAGAAAAAGCAGCCGGTAGACTTAGGTCTGTTAGAGGAAGACGACG AGTTTGAAGAGTTCCCTGCCGAAGACTGGGCTGGCTTAGATGAAGATGAAGATGCACATGTCTGGGAGGATAATTGGGATGATGACAATG TAGAGGATGACTTCTCTAATCAGTTACGGCTTGAGAAAGAGATCCAAGATCTTGAAAAAGCTGAACTGCAAATCTCAACGAAGGAAGAGG CCATTTTAAAGAAACTAAAGTCAATTGAGCGGACAACAGAAGACATTATAAGATCTGTGAAAGTGGAAAGAGAAGAAAGAGCAGAAGAGT CAATTGAGGACATCTATGCTAATATCCCTGACCTTCCAAAGTCCTACATACCTTCTAGGTTAAGGAAGGAGATAAATGAAGAAAAAGAAG ATGATGAACAAAATAGGAAAGCTTTATATGCCATGGAAATTAAAGTTGAAAAAGACTTGAAGACTGGAGAAAGTACAGTTCTGTCTTCAA TACCTCTGCCATCAGATGACTTTAAAGGTACAGGAATAAAAGTTTATGATGATGGGCAAAAGTCAGTGTATGCAGTAAGTTCTAATCACA GTGCAGCATACAATGGCACCGATGGCCTGGCACCAGTTGAAGTAGAGGAACTTCTAAGACAAGCCTCAGAGAGAAACTCTAAATCCCCAA CAGAGTATCATGAGCCTGTATATGCCAATCCCTTTTACAGGCCTACAACCCCACAGAGAGAAACGGTGACCCCTGGACCAAACTTTCAAG AAAGGATAAAGATTAAAACTAATGGACTGGGTATTGGTGTAAATGAATCCATACACAATATGGGCAATGGTCTTTCAGAGGAAAGGGGAA ACAACTTCAATCACATCAGTCCCATTCCGCCAGTGCCTCATCCCCGATCAGTGATTCAACAAGCAGAAGAGAAGCTTCACACCCCGCAAA AAAGGCTAATGACTCCTTGGGAAGAATCGAATGTCATGCAGGACAAAGATGCACCCTCTCCAAAGCCAAGGCTGAGCCCCAGAGAGACAA TATTTGGGAAATCTGAACACCAGAATTCTTCACCCACTTGTCAGGAGGACGAGGAAGATGTCAGATATAATATCGTTCATTCCCTGCCTC CAGACATAAATGATACAGAACCGGTGACAATGATTTTCATGGGGTATCAGCAGGCAGAAGACAGTGAAGAAGATAAGAAGTTTCTGACAG GATATGATGGGATCATCCATGCTGAGCTGGTTGTGATTGATGATGAGGAGGAGGAGGATGAAGGAGAAGCAGAGAAACCGTCCTACCACC CCATAGCTCCCCATAGTCAGGTGTACCAGCCAGCCAAACCAACACCACTTCCTAGAAAAAGATCAGAAGCTAGTCCTCATGAAAACACAA ATCATAAATCCCCCCACAAAAATTCCATATCTCTGAAAGAGCAAGAAGAAAGCTTAGGCAGCCCTGTCCACCATTCCCCATTTGATGCTC AGACAACTGGAGATGGGACTGAGGATCCATCCTTAACAGCTTTAAGGATGAGAATGGCAAAGCTGGGAAAAAAGGTGATCTAAGAGTTGT ACCACCTATATAAACATCCTTTGAAGAAGAAACTAAGAAGCATTTGCAAATTTCTCTTCTGGATATTTTGTTTATTTTTTCTGAAGTCCA AAAAATTATCATTACAGTGTACCATATTAAGCCATGTGAATAAGTAGTAGTCATTATTTGTGAAAAATTCCCAAAAAGCTGGGGAAAACA AATGTGTAACTTTTCCAGTTACTTGACACGATTCAGTGGGGGAAAACCAGCATTTTTTATTCTATTGATACCAAAGCATTTCTAATAAGA GCTTGTTAAATTTAAGAATAAAGTTATTTAAAATATTCTGAGTATAGTATATTAACTGGCATTGTAATTTTGATGATACAAAGATTGAAA GATCATAGGAAAGCATTGCCCTTCATCACAGAAGTATTCAACTCTGACAAATAAATATGTCATCCTGAATTAATAATGCCTTAATAAAAG >In-frame_ENST00000248566_ENST00000263174_TCGA-09-1661_SHFM1_chr7_96324109_-_PALMD_chr1_100152231_length(amino acids)=524AA_start in transcript=128_stop in transcript=1702 MSEKKQPVDLGLLEEDDEFEEFPAEDWAGLDEDEDAHVWEDNWDDDNVEDDFSNQLRLEKEIQDLEKAELQISTKEEAILKKLKSIERTT EDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIKVEKDLKTGESTVLSSIPLPSDDFKGTGI KVYDDGQKSVYAVSSNHSAAYNGTDGLAPVEVEELLRQASERNSKSPTEYHEPVYANPFYRPTTPQRETVTPGPNFQERIKIKTNGLGIG VNESIHNMGNGLSEERGNNFNHISPIPPVPHPRSVIQQAEEKLHTPQKRLMTPWEESNVMQDKDAPSPKPRLSPRETIFGKSEHQNSSPT CQEDEEDVRYNIVHSLPPDINDTEPVTMIFMGYQQAEDSEEDKKFLTGYDGIIHAELVVIDDEEEEDEGEAEKPSYHPIAPHSQVYQPAK -------------------------------------------------------------- >In-frame_ENST00000248566_ENST00000605497_TCGA-09-1661_SHFM1_chr7_96324109_-_PALMD_chr1_100152231_length(transcript)=1864nt_BP=298nt ATTCTTTCCCCAAGTCTCTATGGTAGCGTCAGCGTCGGAGGCGGTAGTGACGGTGGCGTTTCCTTGAGGAAGAGTGAGGGTTCCAACTTT TCTGCTTATCTGGGAGGTGTTGGGCGCGGACAGTCGAGATGTCAGAGAAAAAGCAGCCGGTAGACTTAGGTCTGTTAGAGGAAGACGACG AGTTTGAAGAGTTCCCTGCCGAAGACTGGGCTGGCTTAGATGAAGATGAAGATGCACATGTCTGGGAGGATAATTGGGATGATGACAATG TAGAGGATGACTTCTCTAATCAGTTACGGCTTGAGAAAGAGATCCAAGATCTTGAAAAAGCTGAACTGCAAATCTCAACGAAGGAAGAGG CCATTTTAAAGAAACTAAAGTCAATTGAGCGGACAACAGAAGACATTATAAGATCTGTGAAAGTGGAAAGAGAAGAAAGAGCAGAAGAGT CAATTGAGGACATCTATGCTAATATCCCTGACCTTCCAAAGTCCTACATACCTTCTAGGTTAAGGAAGGAGATAAATGAAGAAAAAGAAG ATGATGAACAAAATAGGAAAGCTTTATATGCCATGGAAATTAAAGTTGAAAAAGACTTGAAGACTGGAGAAAGTACAGTTCTGTCTTCAA TACCTCTGCCATCAGATGACTTTAAAGGTACAGGAATAAAAGTTTATGATGATGGGCAAAAGTCAGTGTATGCAGTAAGTTCTAATCACA GTGCAGCATACAATGGCACCGATGGCCTGGCACCAGTTGAAGTAGAGGAACTTCTAAGACAAGCCTCAGAGAGAAACTCTAAATCCCCAA CAGAGTATCATGAGCCTGTATATGCCAATCCCTTTTACAGGCCTACAACCCCACAGAGAGAAACGGTGACCCCTGGACCAAACTTTCAAG AAAGGATAAAGATTAAAACTAATGGACTGGGTATTGGTGTAAATGAATCCATACACAATATGGGCAATGGTCTTTCAGAGGAAAGGGGAA ACAACTTCAATCACATCAGTCCCATTCCGCCAGTGCCTCATCCCCGATCAGTGATTCAACAAGCAGAAGAGAAGCTTCACACCCCGCAAA AAAGGCTAATGACTCCTTGGGAAGAATCGAATGTCATGCAGGACAAAGATGCACCCTCTCCAAAGCCAAGGCTGAGCCCCAGAGAGACAA TATTTGGGAAATCTGAACACCAGAATTCTTCACCCACTTGTCAGGAGGACGAGGAAGATGTCAGATATAATATCGTTCATTCCCTGCCTC CAGACATAAATGATACAGAACCGGTGACAATGATTTTCATGGGGTATCAGCAGGCAGAAGACAGTGAAGAAGATAAGAAGTTTCTGACAG GATATGATGGGATCATCCATGCTGAGCTGGTTGTGATTGATGATGAGGAGGAGGAGGATGAAGGAGAAGCAGAGAAACCGTCCTACCACC CCATAGCTCCCCATAGTCAGGTGTACCAGCCAGCCAAACCAACACCACTTCCTAGAAAAAGATCAGAAGCTAGTCCTCATGAAAACACAA ATCATAAATCCCCCCACAAAAATTCCATATCTCTGAAAGAGCAAGAAGAAAGCTTAGGCAGCCCTGTCCACCATTCCCCATTTGATGCTC AGACAACTGGAGATGGGACTGAGGATCCATCCTTAACAGGTAATAAAAATGACAAGGCATGCCACTGCTGTTCAGTCATGTGACCAGCTT CTCTTGTGCTAATGCAGTCTTGCTTTCAGGCTTCTCTGACCACCTCATAAACTAATACGCACTGAGATTTTTTTATTAATGCTGATAGAG >In-frame_ENST00000248566_ENST00000605497_TCGA-09-1661_SHFM1_chr7_96324109_-_PALMD_chr1_100152231_length(amino acids)=524AA_start in transcript=128_stop in transcript=1702 MSEKKQPVDLGLLEEDDEFEEFPAEDWAGLDEDEDAHVWEDNWDDDNVEDDFSNQLRLEKEIQDLEKAELQISTKEEAILKKLKSIERTT EDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIKVEKDLKTGESTVLSSIPLPSDDFKGTGI KVYDDGQKSVYAVSSNHSAAYNGTDGLAPVEVEELLRQASERNSKSPTEYHEPVYANPFYRPTTPQRETVTPGPNFQERIKIKTNGLGIG VNESIHNMGNGLSEERGNNFNHISPIPPVPHPRSVIQQAEEKLHTPQKRLMTPWEESNVMQDKDAPSPKPRLSPRETIFGKSEHQNSSPT CQEDEEDVRYNIVHSLPPDINDTEPVTMIFMGYQQAEDSEEDKKFLTGYDGIIHAELVVIDDEEEEDEGEAEKPSYHPIAPHSQVYQPAK -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for SHFM1-PALMD |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for SHFM1-PALMD |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for SHFM1-PALMD |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | PALMD | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
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