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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SLC16A1-SENP6 (FusionGDB2 ID:81713)

Fusion Gene Summary for SLC16A1-SENP6

check button Fusion gene summary
Fusion gene informationFusion gene name: SLC16A1-SENP6
Fusion gene ID: 81713
HgeneTgene
Gene symbol

SLC16A1

SENP6

Gene ID

6566

26054

Gene namesolute carrier family 16 member 1SUMO specific peptidase 6
SynonymsHHF7|MCT|MCT1|MCT1DSSP1|SUSP1
Cytomap

1p13.2

6q14.1

Type of geneprotein-codingprotein-coding
Descriptionmonocarboxylate transporter 1MCT 1solute carrier family 16 (monocarboxylate transporter), member 1solute carrier family 16 (monocarboxylic acid transporters), member 1solute carrier family 16, member 1 (monocarboxylic acid transporter 1)sentrin-specific protease 62810017C20RikSUMO-1-specific protease 1SUMO1/sentrin specific peptidase 6SUMO1/sentrin specific protease 6sentrin/SUMO-specific protease SENP6
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000369626, ENST00000538576, 
ENST00000433570, ENST00000478835, 
ENST00000370010, ENST00000370014, 
ENST00000447266, ENST00000541192, 
ENST00000327284, ENST00000436928, 
Fusion gene scores* DoF score10 X 10 X 4=40010 X 15 X 5=750
# samples 1016
** MAII scorelog2(10/400*10)=-2
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(16/750*10)=-2.22881869049588
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SLC16A1 [Title/Abstract] AND SENP6 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSLC16A1(113471714)-SENP6(76331248), # samples:3
Anticipated loss of major functional domain due to fusion event.SLC16A1-SENP6 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
SLC16A1-SENP6 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
SLC16A1-SENP6 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
SLC16A1-SENP6 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
SLC16A1-SENP6 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneSENP6

GO:0070646

protein modification by small protein removal

20212317


check buttonFusion gene breakpoints across SLC16A1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across SENP6 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-44-2668-01ASLC16A1chr1

113471714

-SENP6chr6

76331248

+
ChimerDB4LUADTCGA-44-2668-01ASLC16A1chr1

113471714

-SENP6chr6

76331248

+
ChimerDB4LUADTCGA-44-2668-01ASLC16A1chr1

113471714

-SENP6chr6

76331248

+


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Fusion Gene ORF analysis for SLC16A1-SENP6

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000369626ENST00000370010SLC16A1chr1

113471714

-SENP6chr6

76331248

+
In-frameENST00000369626ENST00000370014SLC16A1chr1

113471714

-SENP6chr6

76331248

+
In-frameENST00000369626ENST00000447266SLC16A1chr1

113471714

-SENP6chr6

76331248

+
5CDS-intronENST00000369626ENST00000541192SLC16A1chr1

113471714

-SENP6chr6

76331248

+
5CDS-intronENST00000369626ENST00000327284SLC16A1chr1

113471714

-SENP6chr6

76331248

+
5CDS-intronENST00000369626ENST00000436928SLC16A1chr1

113471714

-SENP6chr6

76331248

+
In-frameENST00000538576ENST00000370010SLC16A1chr1

113471714

-SENP6chr6

76331248

+
In-frameENST00000538576ENST00000370014SLC16A1chr1

113471714

-SENP6chr6

76331248

+
In-frameENST00000538576ENST00000447266SLC16A1chr1

113471714

-SENP6chr6

76331248

+
5CDS-intronENST00000538576ENST00000541192SLC16A1chr1

113471714

-SENP6chr6

76331248

+
5CDS-intronENST00000538576ENST00000327284SLC16A1chr1

113471714

-SENP6chr6

76331248

+
5CDS-intronENST00000538576ENST00000436928SLC16A1chr1

113471714

-SENP6chr6

76331248

+
Frame-shiftENST00000433570ENST00000370010SLC16A1chr1

113471714

-SENP6chr6

76331248

+
Frame-shiftENST00000433570ENST00000370014SLC16A1chr1

113471714

-SENP6chr6

76331248

+
Frame-shiftENST00000433570ENST00000447266SLC16A1chr1

113471714

-SENP6chr6

76331248

+
5CDS-intronENST00000433570ENST00000541192SLC16A1chr1

113471714

-SENP6chr6

76331248

+
5CDS-intronENST00000433570ENST00000327284SLC16A1chr1

113471714

-SENP6chr6

76331248

+
5CDS-intronENST00000433570ENST00000436928SLC16A1chr1

113471714

-SENP6chr6

76331248

+
intron-3CDSENST00000478835ENST00000370010SLC16A1chr1

113471714

-SENP6chr6

76331248

+
intron-3CDSENST00000478835ENST00000370014SLC16A1chr1

113471714

-SENP6chr6

76331248

+
intron-3CDSENST00000478835ENST00000447266SLC16A1chr1

113471714

-SENP6chr6

76331248

+
intron-intronENST00000478835ENST00000541192SLC16A1chr1

113471714

-SENP6chr6

76331248

+
intron-intronENST00000478835ENST00000327284SLC16A1chr1

113471714

-SENP6chr6

76331248

+
intron-intronENST00000478835ENST00000436928SLC16A1chr1

113471714

-SENP6chr6

76331248

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000369626SLC16A1chr1113471714-ENST00000370010SENP6chr676331248+415658036338451160
ENST00000369626SLC16A1chr1113471714-ENST00000370014SENP6chr676331248+655458036338661167
ENST00000369626SLC16A1chr1113471714-ENST00000447266SENP6chr676331248+655158036338661167
ENST00000538576SLC16A1chr1113471714-ENST00000370010SENP6chr676331248+4625104983243141160
ENST00000538576SLC16A1chr1113471714-ENST00000370014SENP6chr676331248+7023104983243351167
ENST00000538576SLC16A1chr1113471714-ENST00000447266SENP6chr676331248+7020104983243351167

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000369626ENST00000370010SLC16A1chr1113471714-SENP6chr676331248+0.0001398240.99986017
ENST00000369626ENST00000370014SLC16A1chr1113471714-SENP6chr676331248+5.90E-050.999941
ENST00000369626ENST00000447266SLC16A1chr1113471714-SENP6chr676331248+5.95E-050.9999404
ENST00000538576ENST00000370010SLC16A1chr1113471714-SENP6chr676331248+0.0001627980.99983716
ENST00000538576ENST00000370014SLC16A1chr1113471714-SENP6chr676331248+9.71E-050.99990296
ENST00000538576ENST00000447266SLC16A1chr1113471714-SENP6chr676331248+9.53E-050.99990463

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Fusion Genomic Features for SLC16A1-SENP6


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SLC16A1chr1113471713-SENP6chr676331247+1.18E-070.9999999
SLC16A1chr1113471713-SENP6chr676331247+1.18E-070.9999999

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SLC16A1-SENP6


check button Go to

FGviewer for the breakpoints of chr1:113471714-chr6:76331248

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000369626-251_1572.33333333333333501.0Topological domainCytoplasmic
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000369626-2537_5972.33333333333333501.0Topological domainExtracellular
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000538576-251_1572.33333333333333501.0Topological domainCytoplasmic
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000538576-2537_5972.33333333333333501.0Topological domainExtracellular
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000369626-2516_3672.33333333333333501.0TransmembraneHelical
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000538576-2516_3672.33333333333333501.0TransmembraneHelical
TgeneSENP6chr1:113471714chr6:76331248ENST00000370010023666_111217.3333333333333321106.0RegionNote=Protease
TgeneSENP6chr1:113471714chr6:76331248ENST00000447266024666_111217.3333333333333321113.0RegionNote=Protease

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000369626-25108_11172.33333333333333501.0Topological domainExtracellular
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000369626-25133_14372.33333333333333501.0Topological domainCytoplasmic
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000369626-25165_16672.33333333333333501.0Topological domainExtracellular
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000369626-25188_26272.33333333333333501.0Topological domainCytoplasmic
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000369626-25284_29872.33333333333333501.0Topological domainExtracellular
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000369626-25320_32872.33333333333333501.0Topological domainCytoplasmic
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000369626-25350_35372.33333333333333501.0Topological domainExtracellular
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000369626-25375_38972.33333333333333501.0Topological domainCytoplasmic
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000369626-25411_42272.33333333333333501.0Topological domainExtracellular
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000369626-25444_50072.33333333333333501.0Topological domainCytoplasmic
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000369626-2581_8672.33333333333333501.0Topological domainCytoplasmic
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000538576-25108_11172.33333333333333501.0Topological domainExtracellular
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000538576-25133_14372.33333333333333501.0Topological domainCytoplasmic
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000538576-25165_16672.33333333333333501.0Topological domainExtracellular
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000538576-25188_26272.33333333333333501.0Topological domainCytoplasmic
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000538576-25284_29872.33333333333333501.0Topological domainExtracellular
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000538576-25320_32872.33333333333333501.0Topological domainCytoplasmic
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000538576-25350_35372.33333333333333501.0Topological domainExtracellular
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000538576-25375_38972.33333333333333501.0Topological domainCytoplasmic
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000538576-25411_42272.33333333333333501.0Topological domainExtracellular
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000538576-25444_50072.33333333333333501.0Topological domainCytoplasmic
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000538576-2581_8672.33333333333333501.0Topological domainCytoplasmic
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000369626-25112_13272.33333333333333501.0TransmembraneHelical
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000369626-25144_16472.33333333333333501.0TransmembraneHelical
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000369626-25167_18772.33333333333333501.0TransmembraneHelical
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000369626-25263_28372.33333333333333501.0TransmembraneHelical
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000369626-25299_31972.33333333333333501.0TransmembraneHelical
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000369626-25329_34972.33333333333333501.0TransmembraneHelical
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000369626-25354_37472.33333333333333501.0TransmembraneHelical
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000369626-25390_41072.33333333333333501.0TransmembraneHelical
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000369626-25423_44372.33333333333333501.0TransmembraneHelical
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000369626-2560_8072.33333333333333501.0TransmembraneHelical
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000369626-2587_10772.33333333333333501.0TransmembraneHelical
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000538576-25112_13272.33333333333333501.0TransmembraneHelical
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000538576-25144_16472.33333333333333501.0TransmembraneHelical
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000538576-25167_18772.33333333333333501.0TransmembraneHelical
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000538576-25263_28372.33333333333333501.0TransmembraneHelical
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000538576-25299_31972.33333333333333501.0TransmembraneHelical
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000538576-25329_34972.33333333333333501.0TransmembraneHelical
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000538576-25354_37472.33333333333333501.0TransmembraneHelical
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000538576-25390_41072.33333333333333501.0TransmembraneHelical
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000538576-25423_44372.33333333333333501.0TransmembraneHelical
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000538576-2560_8072.33333333333333501.0TransmembraneHelical
HgeneSLC16A1chr1:113471714chr6:76331248ENST00000538576-2587_10772.33333333333333501.0TransmembraneHelical


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Fusion Gene Sequence for SLC16A1-SENP6


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000369626_ENST00000370010_TCGA-44-2668-01A_SLC16A1_chr1_113471714_-_SENP6_chr6_76331248_length(transcript)=4156nt_BP=580nt
AGAGGGCGCGCGCGGCTGAAAGCGTGTGGAGGCGCGGGCTGCAGTTCGGATGTCTGTGTGGCGGGGAGGGGGCGGCGGCCGGGAGAGACG
ACTCCGCCCCCTGCGCGCATGCTCCGGCCCCGGCGGGTTATAAGGCAGCCTCGCTGGCCCGGCCAGACAAAGTGGTGAGCTGCGACGTGA
CTGGCTAGCTGCGTGGGTACTGGAACAAGCAAACGAGGCAGCGAGCGAAGGACGGGAGCCGGACCCTGGGCCCCGTGGAACTCCAGCCTG
CGCCACCACGTCACGCACACGCTCGGCGCTGCGATCCGCGCATATAACGATATTTGGATTTGACCTGCATTTTGGAATTTATCTACACTT
AAAATGCCACCAGCAGTTGGAGGTCCAGTTGGATACACCCCCCCAGATGGAGGCTGGGGCTGGGCAGTGGTAATTGGAGCTTTCATTTCC
ATCGGCTTCTCTTATGCATTTCCCAAATCAATTACTGTCTTCTTCAAAGAGATTGAAGGTATATTCCATGCCACCACCAGCGAAGTGTCA
TGGATATCCTCCATAATGTTGGCTGTCATGTATGGTGGAGCTTTGGCTAGATCAGAGTCTAAGAGAGATGGAGGTTTTAAAAATAATTGG
AGCTTTGATCATGAAGAAGAAAGTGAAGGAGATACAGATAAAGATGGGACAAATCTGCTCAGTGTGGATGAAGATGAGGATTCTGAAACC
TCAAAAGGAAAAAAGTTAAATCGTCGATCTGAAATTGTTGCTAATAGCTCTGGTGAATTCATCTTGAAGACATATGTAAGACGAAACAAG
TCTGAAAGTTTTAAAACTTTGAAAGGCAACCCAATTGGACTTAACATGTTGAGCAACAATAAGAAATTGAGTGAAAATACGCAAAATACG
TCATTATGTTCTGGAACTGTAGTTCATGGTAGACGTTTTCATCATGCTCATGCACAGATACCAGTAGTAAAAACAGCAGCCCAAAGGAAA
GAATACCCACCTCATGTCCAAAAAGTTGAAATTAATCCTGTAAGGTTAAGTCGGCTCCAAGGTGTTGAACGTATAATGAAGAAAACAGAA
GAGTCCGAATCACAAGTGGAGCCTGAAATTAAGAGGAAAGTACAACAGAAACGACACTGTAGTACCTATCAGCCTACTCCTCCTCTATCT
CCTGCTTCAAAAAAATGTTTAACCCATTTAGAGGATTTGCAAAGAAATTGCAGACAAGCTATTACTTTGAATGAGTCTACTGGACCATTA
TTAAGAACGTCAATTCATCAGAATTCTGGAGGACAGAAGTCACAAAACACAGGATTAACAACCAAGAAGTTTTATGGCAACAATGTGGAA
AAGGTTCCAATTGATATTATTGTGAATTGTGATGACAGTAAACACACTTATTTACAGACTAATGGAAAAGTCATTTTACCTGGGGCAAAA
ATACCCAAAATCACAAACTTGAAAGAAAGGAAAACAAGTTTGTCAGACCTAAATGATCCAATCATTTTGTCCAGTGATGATGATGATGAC
AACGACAGAACTAACAGAAGAGAAAGCATATCTCCTCAGCCTGCTGATTCAGCATGTTCTTCCCCTGCACCATCCACTGGAAAAGTAGAA
GCAGCGCTAAATGAAAATACTTGCAGAGCAGAGCGTGAACTACGAAGCATTCCAGAAGACTCAGAGTTAAATACAGTTACATTGCCAAGA
AAAGCAAGAATGAAAGACCAGTTTGGCAATTCTATTATCAACACACCTCTGAAACGTCGTAAAGTGTTTTCTCAAGAACCTCCAGATGCT
TTAGCTTTAAGCTGCCAAAGTTCCTTTGACAGTGTCATTTTAAACTGTCGAAGTATACGAGTAGGAACACTCTTCCGGCTGTTAATAGAG
CCTGTAATTTTTTGTTTAGATTTTATCAAGATACAGCTAGACGAACCAGACCATGATCCTGTAGAGATTATATTAAATACCTCTGATCTA
ACTAAATGTGAATGGTGTAATGTCCGAAAATTACCTGTAGTGTTTCTTCAAGCAATTCCAGCAGTTTATCAAAAGCTGAGCATCCAACTG
CAAATGAATAAGGAGGATAAAGTTTGGAATGATTGTAAAGGAGTAAATAAATTAACAAATTTAGAAGAACAATATATAATTTTAATTTTT
CAAAATGGCCTTGATCCTCCGGCAAATATGGTATTTGAAAGTATCATTAATGAAATTGGTATAAAGAATAACATCTCCAATTTTTTTGCG
AAAATTCCCTTTGAAGAAGCTAATGGCAGACTTGTTGCCTGTACAAGAACCTATGAAGAGAGCATCAAAGGAAGTTGTGGGCAAAAGGAA
AACAAAATTAAAACTGTATCATTTGAATCTAAAATACAACTTAGAAGCAAACAAGAATTTCAGTTTTTTGATGAAGAAGAAGAAACTGGA
GAAAACCACACCATCTTCATTGGCCCAGTAGAAAAGTTGATAGTATATCCACCACCTCCAGCTAAGGGAGGCATCTCTGTTACCAATGAG
GACCTGCACTGTCTAAATGAAGGAGAATTTTTAAATGATGTTATTATAGACTTTTATTTGAAATACTTGGTGCTTGAAAAACTGAAGAAG
GAAGACGCTGACCGAATTCATATATTCAGTTCTTTTTTCTATAAACGCCTTAATCAGAGAGAGAGGAGAAATCATGAAACAACTAATCTG
TCAATACAGCAAAAACGGCATGGGAGAGTAAAAACATGGACCCGGCACGTAGATATTTTTGAGAAGGATTTTATTTTTGTACCCCTTAAT
GAAGCTGCACACTGGTTTTTGGCTGTTGTTTGTTTCCCCGGTTTGGAAAAACCAAAGTATGAACCTAATCCTCATTACCATGAAAATGCT
GTCATACAGAAATGTTCAACTGTAGAGGACAGTTGTATTTCTTCTTCAGCCAGTGAAATGGAGAGTTGTTCACAAAACTCTTCTGCCAAG
CCTGTAATTAAGAAGATGCTAAACAAAAAACATTGCATAGCTGTAATTGATTCCAATCCTGGGCAGGAAGAAAGTGACCCTCGTTATAAG
AGAAACATATGCAGTGTAAAATACAGTGTGAAAAAAATAAATCATACTGCGAGTGAAAATGAAGAATTCAATAAAGGAGAATCTACATCC
CAGAAAGTTGCTGATAGGACTAAAAGTGAGAATGGCCTACAGAATGAAAGTTTAAGTTCCACACATCATACAGATGGCTTAAGCAAAATC
AGACTAAACTATAGCGATGAATCACCTGAAGCTGGTAAAATGCTTGAAGATGAACTCGTCGACTTCTCAGAAGATCAGGATAACCAGGAT
GATAGCAGTGACGATGGATTCCTCGCTGATGACAACTGCAGTTCAGAAATAGGACAGTGGCATTTAAAGCCTACTATCTGTAAACAACCT
TGTATCCTACTTATGGACTCACTCCGAGGCCCTTCTCGGTCAAATGTTGTCAAAATTTTAAGAGAGTATTTAGAAGTGGAATGGGAAGTT
AAAAAAGGAAGCAAAAGAAGTTTTTCCAAAGATGTTATGAAGGGCTCTAATCCAAAAGTACCACAGCAAAACAACTTCAGTGACTGTGGT
GTATATGTATTGCAGTATGTAGAGAGCTTTTTTGAGAATCCAATTCTCAGTTTTGAACTACCTATGAATTTGGCAAACTGGTTTCCTCCA
CCAAGAATGAGAACAAAAAGAGAAGAAATCCGAAACATAATTCTGAAGCTACAGGAAGATCAGAGCAAAGAGAAAAGAAAGCATAAGGAC
ACTTACTCAACAGAAGCACCTTTAGGCGAAGGAACAGAACAATATGTCAATAGTATCTCAGATTGACCATTTCTGTTACTTGTCATTTCT
ACTTTCAGAAACTAAATGACTTTCAAATTTGGGTATAGACAATAAAGAACTGAAGTGCTCACTACTCAGTGATTTGGAAATTTTGATGCT
TGTATAAATGTCAGATAATTAATTTCCAAAGGCGTATGTATTAAGTAAAAGTCTGTAAATATGTTAATGAGGCCAATTTTTCCAGCATTT
ATAATTATTTTTTTCACTTGTTAGGAAGCTTTTGTTATGTATTTTCTGTTAATAGTACCTAAAATTGCAACTTCTAAACACAAATAAAAA

>In-frame_ENST00000369626_ENST00000370010_TCGA-44-2668-01A_SLC16A1_chr1_113471714_-_SENP6_chr6_76331248_length(amino acids)=1160AA_start in transcript=363_stop in transcript=3845
MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIMLAVMYGGALARSESKRDGGFKNNWS
FDHEEESEGDTDKDGTNLLSVDEDEDSETSKGKKLNRRSEIVANSSGEFILKTYVRRNKSESFKTLKGNPIGLNMLSNNKKLSENTQNTS
LCSGTVVHGRRFHHAHAQIPVVKTAAQRKEYPPHVQKVEINPVRLSRLQGVERIMKKTEESESQVEPEIKRKVQQKRHCSTYQPTPPLSP
ASKKCLTHLEDLQRNCRQAITLNESTGPLLRTSIHQNSGGQKSQNTGLTTKKFYGNNVEKVPIDIIVNCDDSKHTYLQTNGKVILPGAKI
PKITNLKERKTSLSDLNDPIILSSDDDDDNDRTNRRESISPQPADSACSSPAPSTGKVEAALNENTCRAERELRSIPEDSELNTVTLPRK
ARMKDQFGNSIINTPLKRRKVFSQEPPDALALSCQSSFDSVILNCRSIRVGTLFRLLIEPVIFCLDFIKIQLDEPDHDPVEIILNTSDLT
KCEWCNVRKLPVVFLQAIPAVYQKLSIQLQMNKEDKVWNDCKGVNKLTNLEEQYIILIFQNGLDPPANMVFESIINEIGIKNNISNFFAK
IPFEEANGRLVACTRTYEESIKGSCGQKENKIKTVSFESKIQLRSKQEFQFFDEEEETGENHTIFIGPVEKLIVYPPPPAKGGISVTNED
LHCLNEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRNHETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNE
AAHWFLAVVCFPGLEKPKYEPNPHYHENAVIQKCSTVEDSCISSSASEMESCSQNSSAKPVIKKMLNKKHCIAVIDSNPGQEESDPRYKR
NICSVKYSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQNESLSSTHHTDGLSKIRLNYSDESPEAGKMLEDELVDFSEDQDNQDD
SSDDGFLADDNCSSEIGQWHLKPTICKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPKVPQQNNFSDCGV

--------------------------------------------------------------
>In-frame_ENST00000369626_ENST00000370014_TCGA-44-2668-01A_SLC16A1_chr1_113471714_-_SENP6_chr6_76331248_length(transcript)=6554nt_BP=580nt
AGAGGGCGCGCGCGGCTGAAAGCGTGTGGAGGCGCGGGCTGCAGTTCGGATGTCTGTGTGGCGGGGAGGGGGCGGCGGCCGGGAGAGACG
ACTCCGCCCCCTGCGCGCATGCTCCGGCCCCGGCGGGTTATAAGGCAGCCTCGCTGGCCCGGCCAGACAAAGTGGTGAGCTGCGACGTGA
CTGGCTAGCTGCGTGGGTACTGGAACAAGCAAACGAGGCAGCGAGCGAAGGACGGGAGCCGGACCCTGGGCCCCGTGGAACTCCAGCCTG
CGCCACCACGTCACGCACACGCTCGGCGCTGCGATCCGCGCATATAACGATATTTGGATTTGACCTGCATTTTGGAATTTATCTACACTT
AAAATGCCACCAGCAGTTGGAGGTCCAGTTGGATACACCCCCCCAGATGGAGGCTGGGGCTGGGCAGTGGTAATTGGAGCTTTCATTTCC
ATCGGCTTCTCTTATGCATTTCCCAAATCAATTACTGTCTTCTTCAAAGAGATTGAAGGTATATTCCATGCCACCACCAGCGAAGTGTCA
TGGATATCCTCCATAATGTTGGCTGTCATGTATGGTGGAGCTTTGGCTAGATCAGAGTCTAAGAGAGATGGAGGTTTTAAAAATAATTGG
AGCTTTGATCATGAAGAAGAAAGTGAAGGAGATACAGATAAAGATGGGACAAATCTGCTCAGTGTGGATGAAGATGAGGATTCTGAAACC
TCAAAAGGAAAAAAGTTAAATCGTCGATCTGAAATTGTTGCTAATAGCTCTGGTGAATTCATCTTGAAGACATATGTAAGACGAAACAAG
TCTGAAAGTTTTAAAACTTTGAAAGGCAACCCAATTGGACTTAACATGTTGAGCAACAATAAGAAATTGAGTGAAAATACGCAAAATACG
TCATTATGTTCTGGAACTGTAGTTCATGGTAGACGTTTTCATCATGCTCATGCACAGATACCAGTAGTAAAAACAGCAGCCCAAAGGCTT
TTGAGTAATCAGATTCTGAAAGAATACCCACCTCATGTCCAAAAAGTTGAAATTAATCCTGTAAGGTTAAGTCGGCTCCAAGGTGTTGAA
CGTATAATGAAGAAAACAGAAGAGTCCGAATCACAAGTGGAGCCTGAAATTAAGAGGAAAGTACAACAGAAACGACACTGTAGTACCTAT
CAGCCTACTCCTCCTCTATCTCCTGCTTCAAAAAAATGTTTAACCCATTTAGAGGATTTGCAAAGAAATTGCAGACAAGCTATTACTTTG
AATGAGTCTACTGGACCATTATTAAGAACGTCAATTCATCAGAATTCTGGAGGACAGAAGTCACAAAACACAGGATTAACAACCAAGAAG
TTTTATGGCAACAATGTGGAAAAGGTTCCAATTGATATTATTGTGAATTGTGATGACAGTAAACACACTTATTTACAGACTAATGGAAAA
GTCATTTTACCTGGGGCAAAAATACCCAAAATCACAAACTTGAAAGAAAGGAAAACAAGTTTGTCAGACCTAAATGATCCAATCATTTTG
TCCAGTGATGATGATGATGACAACGACAGAACTAACAGAAGAGAAAGCATATCTCCTCAGCCTGCTGATTCAGCATGTTCTTCCCCTGCA
CCATCCACTGGAAAAGTAGAAGCAGCGCTAAATGAAAATACTTGCAGAGCAGAGCGTGAACTACGAAGCATTCCAGAAGACTCAGAGTTA
AATACAGTTACATTGCCAAGAAAAGCAAGAATGAAAGACCAGTTTGGCAATTCTATTATCAACACACCTCTGAAACGTCGTAAAGTGTTT
TCTCAAGAACCTCCAGATGCTTTAGCTTTAAGCTGCCAAAGTTCCTTTGACAGTGTCATTTTAAACTGTCGAAGTATACGAGTAGGAACA
CTCTTCCGGCTGTTAATAGAGCCTGTAATTTTTTGTTTAGATTTTATCAAGATACAGCTAGACGAACCAGACCATGATCCTGTAGAGATT
ATATTAAATACCTCTGATCTAACTAAATGTGAATGGTGTAATGTCCGAAAATTACCTGTAGTGTTTCTTCAAGCAATTCCAGCAGTTTAT
CAAAAGCTGAGCATCCAACTGCAAATGAATAAGGAGGATAAAGTTTGGAATGATTGTAAAGGAGTAAATAAATTAACAAATTTAGAAGAA
CAATATATAATTTTAATTTTTCAAAATGGCCTTGATCCTCCGGCAAATATGGTATTTGAAAGTATCATTAATGAAATTGGTATAAAGAAT
AACATCTCCAATTTTTTTGCGAAAATTCCCTTTGAAGAAGCTAATGGCAGACTTGTTGCCTGTACAAGAACCTATGAAGAGAGCATCAAA
GGAAGTTGTGGGCAAAAGGAAAACAAAATTAAAACTGTATCATTTGAATCTAAAATACAACTTAGAAGCAAACAAGAATTTCAGTTTTTT
GATGAAGAAGAAGAAACTGGAGAAAACCACACCATCTTCATTGGCCCAGTAGAAAAGTTGATAGTATATCCACCACCTCCAGCTAAGGGA
GGCATCTCTGTTACCAATGAGGACCTGCACTGTCTAAATGAAGGAGAATTTTTAAATGATGTTATTATAGACTTTTATTTGAAATACTTG
GTGCTTGAAAAACTGAAGAAGGAAGACGCTGACCGAATTCATATATTCAGTTCTTTTTTCTATAAACGCCTTAATCAGAGAGAGAGGAGA
AATCATGAAACAACTAATCTGTCAATACAGCAAAAACGGCATGGGAGAGTAAAAACATGGACCCGGCACGTAGATATTTTTGAGAAGGAT
TTTATTTTTGTACCCCTTAATGAAGCTGCACACTGGTTTTTGGCTGTTGTTTGTTTCCCCGGTTTGGAAAAACCAAAGTATGAACCTAAT
CCTCATTACCATGAAAATGCTGTCATACAGAAATGTTCAACTGTAGAGGACAGTTGTATTTCTTCTTCAGCCAGTGAAATGGAGAGTTGT
TCACAAAACTCTTCTGCCAAGCCTGTAATTAAGAAGATGCTAAACAAAAAACATTGCATAGCTGTAATTGATTCCAATCCTGGGCAGGAA
GAAAGTGACCCTCGTTATAAGAGAAACATATGCAGTGTAAAATACAGTGTGAAAAAAATAAATCATACTGCGAGTGAAAATGAAGAATTC
AATAAAGGAGAATCTACATCCCAGAAAGTTGCTGATAGGACTAAAAGTGAGAATGGCCTACAGAATGAAAGTTTAAGTTCCACACATCAT
ACAGATGGCTTAAGCAAAATCAGACTAAACTATAGCGATGAATCACCTGAAGCTGGTAAAATGCTTGAAGATGAACTCGTCGACTTCTCA
GAAGATCAGGATAACCAGGATGATAGCAGTGACGATGGATTCCTCGCTGATGACAACTGCAGTTCAGAAATAGGACAGTGGCATTTAAAG
CCTACTATCTGTAAACAACCTTGTATCCTACTTATGGACTCACTCCGAGGCCCTTCTCGGTCAAATGTTGTCAAAATTTTAAGAGAGTAT
TTAGAAGTGGAATGGGAAGTTAAAAAAGGAAGCAAAAGAAGTTTTTCCAAAGATGTTATGAAGGGCTCTAATCCAAAAGTACCACAGCAA
AACAACTTCAGTGACTGTGGTGTATATGTATTGCAGTATGTAGAGAGCTTTTTTGAGAATCCAATTCTCAGTTTTGAACTACCTATGAAT
TTGGCAAACTGGTTTCCTCCACCAAGAATGAGAACAAAAAGAGAAGAAATCCGAAACATAATTCTGAAGCTACAGGAAGATCAGAGCAAA
GAGAAAAGAAAGCATAAGGACACTTACTCAACAGAAGCACCTTTAGGCGAAGGAACAGAACAATATGTCAATAGTATCTCAGATTGACCA
TTTCTGTTACTTGTCATTTCTACTTTCAGAAACTAAATGACTTTCAAATTTGGGTATAGACAATAAAGAACTGAAGTGCTCACTACTCAG
TGATTTGGAAATTTTGATGCTTGTATAAATGTCAGATAATTAATTTCCAAAGGCGTATGTATTAAGTAAAAGTCTGTAAATATGTTAATG
AGGCCAATTTTTCCAGCATTTATAATTATTTTTTTCACTTGTTAGGAAGCTTTTGTTATGTATTTTCTGTTAATAGTACCTAAAATTGCA
ACTTCTAAACACAAATAAAAAGAAAATATTTATAGGAGGAAATGATTAATTTGATATTCTTTAGTGAACTTGTTTAATTCCTCAGTGGGT
GTGACATATTTCATGGGAATATTCAAATATCTATGGTAATATTTTGACCCTTTATATTTGTTCTAAAATAAGTCAAAATGTGAAAATAAT
ATTAAATCTAAGATATTTTGAACTAAGCATCTTTATATGCTTGTGTAACAGGAACAAAGTAACAGCCTTTCAATTCATATACTGCCTTGT
GTTCAGTGAACCCAAGAAATGTAATAAATATTTGTAATTTTACACAAATATTTAAGAGGAAAGAGTATTAAGAGCAATTCAAAAAAAGTA
ACCTTATACTACTAAAAAAAAAATTCTTGCATATATTATCATCAAATGCATTTTTGAAGACATCAAAGACTCAGGTTAAAACTATTTTGG
TAAGTGCAGCTTGAATTTCAAATATCCCGTGTTACCTTTCTCTATTACAGCTTAAAGTATGCTACAATCTGTGTCATATAGTTAATTGAT
AAGCATTTTTAATCTGTGTAAACACAGGAATTTAAATAGGAATTTACTATTTTTTTATAAAGCTTTTGCTATTTTTTCATTGCTCATTTT
GTTCTTATTATTTTGATAAAGTATCAGACTTTTTGCTTGAGTTCTTCAGTGTAAATTATTTTTTACATGTAAAAGTACTGTATTCAACCA
GTTGCATAATACAGCAAAAATCTTTGAATTCCCCTTTAAAATAACTAAAATTTGATGGTTTCCATGACAGATTTATAGCACATATAGGGA
TCTTGCATGTATCTGCAGAAACTTCATTATTTTTCAAATGAAATGGTGTATACTTCTTTCAAATGAACTTTGAGACTTGAAACATATTTT
AGTCATTTTTTGTTAAATATTGAATTTTTAAATACACATATATCAAAAATAGTTGAGAATAAAAAGAAAGCCTAATCATCAGCAATTATT
TTATTTTTAATTTGGCCATCTCTGACATTGCAGTCAATATCTTAGGGTATTTTCTTGAATTTAATAAAGTCCCATGGGTGGGTTCAGGGT
GAATGGGAGTATTAACAACAACCAAAAAATATCTATTGAGACACAGTAGAGTCTCAGTAAGAGAAATATTAAAATGTAAGAAAGGTCACC
ATTAGTGATATCAACTGTAGTTTGTTACTTTGAACTATATTTCTGATTAACTCTTTATAGTAATAACTTAGAGCTGTTAGCTCAGATATC
TTAATTAGCTCATATGAAAAACAAGTTTAATTTTATTATTTACTGAACATGGCAAAATGCTTTTCAATCTATAATAAAACTGGGATAAAA
AATTGAAGTTGTTTTTTTTAAAACCTAATAGCAATAAGCAAAATTGGCATACATAATTTTTTTAATGAACTATATTTTGTCAGAATCTGA
AGGTACTGAAAAACTATTCTAAAATGCCTACTTGTTTTTGCATTAATTTGTAATGCTTACATTTTGCACCCTTAGATAATGTTTGATAAG
ATAAAAATATAATTTATCCCTTGTACCAACTCAAGTCAATCAGATTTTAACATGAAAAATATAGATTAATGTATGTCAGCTTTCTAGAGG
TAGAATACTCAGCTATTTGATGGCATTTTTCCCACCCCATGTGAAATTTTATTTTTGGAAGTTATGCTAGTGACATTGCAATATATATTG
AAATCTTCGGAGGCTGCCAGGTTGAGCTTCAAAACTAGACTTGAGAATCTTTCGTGTATATGCACATTCACTTGATAATTGTGTATTCTA
TGTAGTTTAAAGTGGGATCAAGCCTTTTAAAATGTGTTATTAGTACTTAGAAGTTGTAAAACAGAACTTATAGAGGTTTGTTACTAGACA
CTGAAACTGCATGACAAGTATCTGGTGTCTTAACTAATTAGATAGATCTGTTGTATTGGTTTTCTTGTTGGATAGAATAACAGTTAATCA
TTTTTAGAAGAGTTTTAGATTACTTGCCATAAAATTTGTATGTCTCAGCTCTTGTTGGTTTAGGAGCAGAAGTGGTGTTTAGTCCCTTCC
CGTTAATGTTGCTGTGCTACTTCAGACAGCTGAAAACTTAATGGTATTATTTCAAGTTCACATAACCCTAAAAAAGGTTTTCTTTGTGTA
GTAACTTGTGCTTAAACTTTTAGTCAATTAAATGTAGGAGGTTTTATTTGAAAACATAAAATGATTCTCTAAATTACATCTTGTTTTAAG
CCACCAAAATGAATGCAGTAATTTTTCTTTAAAAAAATGATCTCTGAAAACTGTGAGACAATGTAAAAAGAATAAGTTTTAATTCCCCCA

>In-frame_ENST00000369626_ENST00000370014_TCGA-44-2668-01A_SLC16A1_chr1_113471714_-_SENP6_chr6_76331248_length(amino acids)=1167AA_start in transcript=363_stop in transcript=3866
MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIMLAVMYGGALARSESKRDGGFKNNWS
FDHEEESEGDTDKDGTNLLSVDEDEDSETSKGKKLNRRSEIVANSSGEFILKTYVRRNKSESFKTLKGNPIGLNMLSNNKKLSENTQNTS
LCSGTVVHGRRFHHAHAQIPVVKTAAQRLLSNQILKEYPPHVQKVEINPVRLSRLQGVERIMKKTEESESQVEPEIKRKVQQKRHCSTYQ
PTPPLSPASKKCLTHLEDLQRNCRQAITLNESTGPLLRTSIHQNSGGQKSQNTGLTTKKFYGNNVEKVPIDIIVNCDDSKHTYLQTNGKV
ILPGAKIPKITNLKERKTSLSDLNDPIILSSDDDDDNDRTNRRESISPQPADSACSSPAPSTGKVEAALNENTCRAERELRSIPEDSELN
TVTLPRKARMKDQFGNSIINTPLKRRKVFSQEPPDALALSCQSSFDSVILNCRSIRVGTLFRLLIEPVIFCLDFIKIQLDEPDHDPVEII
LNTSDLTKCEWCNVRKLPVVFLQAIPAVYQKLSIQLQMNKEDKVWNDCKGVNKLTNLEEQYIILIFQNGLDPPANMVFESIINEIGIKNN
ISNFFAKIPFEEANGRLVACTRTYEESIKGSCGQKENKIKTVSFESKIQLRSKQEFQFFDEEEETGENHTIFIGPVEKLIVYPPPPAKGG
ISVTNEDLHCLNEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRNHETTNLSIQQKRHGRVKTWTRHVDIFEKDF
IFVPLNEAAHWFLAVVCFPGLEKPKYEPNPHYHENAVIQKCSTVEDSCISSSASEMESCSQNSSAKPVIKKMLNKKHCIAVIDSNPGQEE
SDPRYKRNICSVKYSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQNESLSSTHHTDGLSKIRLNYSDESPEAGKMLEDELVDFSE
DQDNQDDSSDDGFLADDNCSSEIGQWHLKPTICKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPKVPQQN

--------------------------------------------------------------
>In-frame_ENST00000369626_ENST00000447266_TCGA-44-2668-01A_SLC16A1_chr1_113471714_-_SENP6_chr6_76331248_length(transcript)=6551nt_BP=580nt
AGAGGGCGCGCGCGGCTGAAAGCGTGTGGAGGCGCGGGCTGCAGTTCGGATGTCTGTGTGGCGGGGAGGGGGCGGCGGCCGGGAGAGACG
ACTCCGCCCCCTGCGCGCATGCTCCGGCCCCGGCGGGTTATAAGGCAGCCTCGCTGGCCCGGCCAGACAAAGTGGTGAGCTGCGACGTGA
CTGGCTAGCTGCGTGGGTACTGGAACAAGCAAACGAGGCAGCGAGCGAAGGACGGGAGCCGGACCCTGGGCCCCGTGGAACTCCAGCCTG
CGCCACCACGTCACGCACACGCTCGGCGCTGCGATCCGCGCATATAACGATATTTGGATTTGACCTGCATTTTGGAATTTATCTACACTT
AAAATGCCACCAGCAGTTGGAGGTCCAGTTGGATACACCCCCCCAGATGGAGGCTGGGGCTGGGCAGTGGTAATTGGAGCTTTCATTTCC
ATCGGCTTCTCTTATGCATTTCCCAAATCAATTACTGTCTTCTTCAAAGAGATTGAAGGTATATTCCATGCCACCACCAGCGAAGTGTCA
TGGATATCCTCCATAATGTTGGCTGTCATGTATGGTGGAGCTTTGGCTAGATCAGAGTCTAAGAGAGATGGAGGTTTTAAAAATAATTGG
AGCTTTGATCATGAAGAAGAAAGTGAAGGAGATACAGATAAAGATGGGACAAATCTGCTCAGTGTGGATGAAGATGAGGATTCTGAAACC
TCAAAAGGAAAAAAGTTAAATCGTCGATCTGAAATTGTTGCTAATAGCTCTGGTGAATTCATCTTGAAGACATATGTAAGACGAAACAAG
TCTGAAAGTTTTAAAACTTTGAAAGGCAACCCAATTGGACTTAACATGTTGAGCAACAATAAGAAATTGAGTGAAAATACGCAAAATACG
TCATTATGTTCTGGAACTGTAGTTCATGGTAGACGTTTTCATCATGCTCATGCACAGATACCAGTAGTAAAAACAGCAGCCCAAAGCAGT
CTGGACCGAAAAGAAAGGAAAGAATACCCACCTCATGTCCAAAAAGTTGAAATTAATCCTGTAAGGTTAAGTCGGCTCCAAGGTGTTGAA
CGTATAATGAAGAAAACAGAAGAGTCCGAATCACAAGTGGAGCCTGAAATTAAGAGGAAAGTACAACAGAAACGACACTGTAGTACCTAT
CAGCCTACTCCTCCTCTATCTCCTGCTTCAAAAAAATGTTTAACCCATTTAGAGGATTTGCAAAGAAATTGCAGACAAGCTATTACTTTG
AATGAGTCTACTGGACCATTATTAAGAACGTCAATTCATCAGAATTCTGGAGGACAGAAGTCACAAAACACAGGATTAACAACCAAGAAG
TTTTATGGCAACAATGTGGAAAAGGTTCCAATTGATATTATTGTGAATTGTGATGACAGTAAACACACTTATTTACAGACTAATGGAAAA
GTCATTTTACCTGGGGCAAAAATACCCAAAATCACAAACTTGAAAGAAAGGAAAACAAGTTTGTCAGACCTAAATGATCCAATCATTTTG
TCCAGTGATGATGATGATGACAACGACAGAACTAACAGAAGAGAAAGCATATCTCCTCAGCCTGCTGATTCAGCATGTTCTTCCCCTGCA
CCATCCACTGGAAAAGTAGAAGCAGCGCTAAATGAAAATACTTGCAGAGCAGAGCGTGAACTACGAAGCATTCCAGAAGACTCAGAGTTA
AATACAGTTACATTGCCAAGAAAAGCAAGAATGAAAGACCAGTTTGGCAATTCTATTATCAACACACCTCTGAAACGTCGTAAAGTGTTT
TCTCAAGAACCTCCAGATGCTTTAGCTTTAAGCTGCCAAAGTTCCTTTGACAGTGTCATTTTAAACTGTCGAAGTATACGAGTAGGAACA
CTCTTCCGGCTGTTAATAGAGCCTGTAATTTTTTGTTTAGATTTTATCAAGATACAGCTAGACGAACCAGACCATGATCCTGTAGAGATT
ATATTAAATACCTCTGATCTAACTAAATGTGAATGGTGTAATGTCCGAAAATTACCTGTAGTGTTTCTTCAAGCAATTCCAGCAGTTTAT
CAAAAGCTGAGCATCCAACTGCAAATGAATAAGGAGGATAAAGTTTGGAATGATTGTAAAGGAGTAAATAAATTAACAAATTTAGAAGAA
CAATATATAATTTTAATTTTTCAAAATGGCCTTGATCCTCCGGCAAATATGGTATTTGAAAGTATCATTAATGAAATTGGTATAAAGAAT
AACATCTCCAATTTTTTTGCGAAAATTCCCTTTGAAGAAGCTAATGGCAGACTTGTTGCCTGTACAAGAACCTATGAAGAGAGCATCAAA
GGAAGTTGTGGGCAAAAGGAAAACAAAATTAAAACTGTATCATTTGAATCTAAAATACAACTTAGAAGCAAACAAGAATTTCAGTTTTTT
GATGAAGAAGAAGAAACTGGAGAAAACCACACCATCTTCATTGGCCCAGTAGAAAAGTTGATAGTATATCCACCACCTCCAGCTAAGGGA
GGCATCTCTGTTACCAATGAGGACCTGCACTGTCTAAATGAAGGAGAATTTTTAAATGATGTTATTATAGACTTTTATTTGAAATACTTG
GTGCTTGAAAAACTGAAGAAGGAAGACGCTGACCGAATTCATATATTCAGTTCTTTTTTCTATAAACGCCTTAATCAGAGAGAGAGGAGA
AATCATGAAACAACTAATCTGTCAATACAGCAAAAACGGCATGGGAGAGTAAAAACATGGACCCGGCACGTAGATATTTTTGAGAAGGAT
TTTATTTTTGTACCCCTTAATGAAGCTGCACACTGGTTTTTGGCTGTTGTTTGTTTCCCCGGTTTGGAAAAACCAAAGTATGAACCTAAT
CCTCATTACCATGAAAATGCTGTCATACAGAAATGTTCAACTGTAGAGGACAGTTGTATTTCTTCTTCAGCCAGTGAAATGGAGAGTTGT
TCACAAAACTCTTCTGCCAAGCCTGTAATTAAGAAGATGCTAAACAAAAAACATTGCATAGCTGTAATTGATTCCAATCCTGGGCAGGAA
GAAAGTGACCCTCGTTATAAGAGAAACATATGCAGTGTAAAATACAGTGTGAAAAAAATAAATCATACTGCGAGTGAAAATGAAGAATTC
AATAAAGGAGAATCTACATCCCAGAAAGTTGCTGATAGGACTAAAAGTGAGAATGGCCTACAGAATGAAAGTTTAAGTTCCACACATCAT
ACAGATGGCTTAAGCAAAATCAGACTAAACTATAGCGATGAATCACCTGAAGCTGGTAAAATGCTTGAAGATGAACTCGTCGACTTCTCA
GAAGATCAGGATAACCAGGATGATAGCAGTGACGATGGATTCCTCGCTGATGACAACTGCAGTTCAGAAATAGGACAGTGGCATTTAAAG
CCTACTATCTGTAAACAACCTTGTATCCTACTTATGGACTCACTCCGAGGCCCTTCTCGGTCAAATGTTGTCAAAATTTTAAGAGAGTAT
TTAGAAGTGGAATGGGAAGTTAAAAAAGGAAGCAAAAGAAGTTTTTCCAAAGATGTTATGAAGGGCTCTAATCCAAAAGTACCACAGCAA
AACAACTTCAGTGACTGTGGTGTATATGTATTGCAGTATGTAGAGAGCTTTTTTGAGAATCCAATTCTCAGTTTTGAACTACCTATGAAT
TTGGCAAACTGGTTTCCTCCACCAAGAATGAGAACAAAAAGAGAAGAAATCCGAAACATAATTCTGAAGCTACAGGAAGATCAGAGCAAA
GAGAAAAGAAAGCATAAGGACACTTACTCAACAGAAGCACCTTTAGGCGAAGGAACAGAACAATATGTCAATAGTATCTCAGATTGACCA
TTTCTGTTACTTGTCATTTCTACTTTCAGAAACTAAATGACTTTCAAATTTGGGTATAGACAATAAAGAACTGAAGTGCTCACTACTCAG
TGATTTGGAAATTTTGATGCTTGTATAAATGTCAGATAATTAATTTCCAAAGGCGTATGTATTAAGTAAAAGTCTGTAAATATGTTAATG
AGGCCAATTTTTCCAGCATTTATAATTATTTTTTTCACTTGTTAGGAAGCTTTTGTTATGTATTTTCTGTTAATAGTACCTAAAATTGCA
ACTTCTAAACACAAATAAAAAGAAAATATTTATAGGAGGAAATGATTAATTTGATATTCTTTAGTGAACTTGTTTAATTCCTCAGTGGGT
GTGACATATTTCATGGGAATATTCAAATATCTATGGTAATATTTTGACCCTTTATATTTGTTCTAAAATAAGTCAAAATGTGAAAATAAT
ATTAAATCTAAGATATTTTGAACTAAGCATCTTTATATGCTTGTGTAACAGGAACAAAGTAACAGCCTTTCAATTCATATACTGCCTTGT
GTTCAGTGAACCCAAGAAATGTAATAAATATTTGTAATTTTACACAAATATTTAAGAGGAAAGAGTATTAAGAGCAATTCAAAAAAAGTA
ACCTTATACTACTAAAAAAAAAATTCTTGCATATATTATCATCAAATGCATTTTTGAAGACATCAAAGACTCAGGTTAAAACTATTTTGG
TAAGTGCAGCTTGAATTTCAAATATCCCGTGTTACCTTTCTCTATTACAGCTTAAAGTATGCTACAATCTGTGTCATATAGTTAATTGAT
AAGCATTTTTAATCTGTGTAAACACAGGAATTTAAATAGGAATTTACTATTTTTTTATAAAGCTTTTGCTATTTTTTCATTGCTCATTTT
GTTCTTATTATTTTGATAAAGTATCAGACTTTTTGCTTGAGTTCTTCAGTGTAAATTATTTTTTACATGTAAAAGTACTGTATTCAACCA
GTTGCATAATACAGCAAAAATCTTTGAATTCCCCTTTAAAATAACTAAAATTTGATGGTTTCCATGACAGATTTATAGCACATATAGGGA
TCTTGCATGTATCTGCAGAAACTTCATTATTTTTCAAATGAAATGGTGTATACTTCTTTCAAATGAACTTTGAGACTTGAAACATATTTT
AGTCATTTTTTGTTAAATATTGAATTTTTAAATACACATATATCAAAAATAGTTGAGAATAAAAAGAAAGCCTAATCATCAGCAATTATT
TTATTTTTAATTTGGCCATCTCTGACATTGCAGTCAATATCTTAGGGTATTTTCTTGAATTTAATAAAGTCCCATGGGTGGGTTCAGGGT
GAATGGGAGTATTAACAACAACCAAAAAATATCTATTGAGACACAGTAGAGTCTCAGTAAGAGAAATATTAAAATGTAAGAAAGGTCACC
ATTAGTGATATCAACTGTAGTTTGTTACTTTGAACTATATTTCTGATTAACTCTTTATAGTAATAACTTAGAGCTGTTAGCTCAGATATC
TTAATTAGCTCATATGAAAAACAAGTTTAATTTTATTATTTACTGAACATGGCAAAATGCTTTTCAATCTATAATAAAACTGGGATAAAA
AATTGAAGTTGTTTTTTTTAAAACCTAATAGCAATAAGCAAAATTGGCATACATAATTTTTTTAATGAACTATATTTTGTCAGAATCTGA
AGGTACTGAAAAACTATTCTAAAATGCCTACTTGTTTTTGCATTAATTTGTAATGCTTACATTTTGCACCCTTAGATAATGTTTGATAAG
ATAAAAATATAATTTATCCCTTGTACCAACTCAAGTCAATCAGATTTTAACATGAAAAATATAGATTAATGTATGTCAGCTTTCTAGAGG
TAGAATACTCAGCTATTTGATGGCATTTTTCCCACCCCATGTGAAATTTTATTTTTGGAAGTTATGCTAGTGACATTGCAATATATATTG
AAATCTTCGGAGGCTGCCAGGTTGAGCTTCAAAACTAGACTTGAGAATCTTTCGTGTATATGCACATTCACTTGATAATTGTGTATTCTA
TGTAGTTTAAAGTGGGATCAAGCCTTTTAAAATGTGTTATTAGTACTTAGAAGTTGTAAAACAGAACTTATAGAGGTTTGTTACTAGACA
CTGAAACTGCATGACAAGTATCTGGTGTCTTAACTAATTAGATAGATCTGTTGTATTGGTTTTCTTGTTGGATAGAATAACAGTTAATCA
TTTTTAGAAGAGTTTTAGATTACTTGCCATAAAATTTGTATGTCTCAGCTCTTGTTGGTTTAGGAGCAGAAGTGGTGTTTAGTCCCTTCC
CGTTAATGTTGCTGTGCTACTTCAGACAGCTGAAAACTTAATGGTATTATTTCAAGTTCACATAACCCTAAAAAAGGTTTTCTTTGTGTA
GTAACTTGTGCTTAAACTTTTAGTCAATTAAATGTAGGAGGTTTTATTTGAAAACATAAAATGATTCTCTAAATTACATCTTGTTTTAAG
CCACCAAAATGAATGCAGTAATTTTTCTTTAAAAAAATGATCTCTGAAAACTGTGAGACAATGTAAAAAGAATAAGTTTTAATTCCCCCA

>In-frame_ENST00000369626_ENST00000447266_TCGA-44-2668-01A_SLC16A1_chr1_113471714_-_SENP6_chr6_76331248_length(amino acids)=1167AA_start in transcript=363_stop in transcript=3866
MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIMLAVMYGGALARSESKRDGGFKNNWS
FDHEEESEGDTDKDGTNLLSVDEDEDSETSKGKKLNRRSEIVANSSGEFILKTYVRRNKSESFKTLKGNPIGLNMLSNNKKLSENTQNTS
LCSGTVVHGRRFHHAHAQIPVVKTAAQSSLDRKERKEYPPHVQKVEINPVRLSRLQGVERIMKKTEESESQVEPEIKRKVQQKRHCSTYQ
PTPPLSPASKKCLTHLEDLQRNCRQAITLNESTGPLLRTSIHQNSGGQKSQNTGLTTKKFYGNNVEKVPIDIIVNCDDSKHTYLQTNGKV
ILPGAKIPKITNLKERKTSLSDLNDPIILSSDDDDDNDRTNRRESISPQPADSACSSPAPSTGKVEAALNENTCRAERELRSIPEDSELN
TVTLPRKARMKDQFGNSIINTPLKRRKVFSQEPPDALALSCQSSFDSVILNCRSIRVGTLFRLLIEPVIFCLDFIKIQLDEPDHDPVEII
LNTSDLTKCEWCNVRKLPVVFLQAIPAVYQKLSIQLQMNKEDKVWNDCKGVNKLTNLEEQYIILIFQNGLDPPANMVFESIINEIGIKNN
ISNFFAKIPFEEANGRLVACTRTYEESIKGSCGQKENKIKTVSFESKIQLRSKQEFQFFDEEEETGENHTIFIGPVEKLIVYPPPPAKGG
ISVTNEDLHCLNEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRNHETTNLSIQQKRHGRVKTWTRHVDIFEKDF
IFVPLNEAAHWFLAVVCFPGLEKPKYEPNPHYHENAVIQKCSTVEDSCISSSASEMESCSQNSSAKPVIKKMLNKKHCIAVIDSNPGQEE
SDPRYKRNICSVKYSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQNESLSSTHHTDGLSKIRLNYSDESPEAGKMLEDELVDFSE
DQDNQDDSSDDGFLADDNCSSEIGQWHLKPTICKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPKVPQQN

--------------------------------------------------------------
>In-frame_ENST00000538576_ENST00000370010_TCGA-44-2668-01A_SLC16A1_chr1_113471714_-_SENP6_chr6_76331248_length(transcript)=4625nt_BP=1049nt
GCTCGGCGCTGCGATCCGCGCATATAACGGTTAGTTGGGTAACAGCCGGCGGCACGCGGCGCGGACCCCACGGTGCCCTCGCTGCCCTGG
TGGGGTCGGAGGGGACCTCCGGGGTTGGGAGACTTTGTCTCCGGCGGAGGGAGGCGGCCCAGCAGAGGGCATCGTGGTCACAGGCAGCCG
CGTGGCCTCGGACTGCAGTGCTGGTGAAGGAGACCTTGAGGCGCTGGGGTCAGCGCCTCTCTTAGCCGAGCCGCGGGCCCCGTGCTAAGA
TGCCGGTCCCAGGCCTGGCCGAGGAGTTGGGTCGTGGTGCCCGGTGACGGTGGGGAAGTCCCTTCCCCCCTAAGTCTTCAATAGGCTCCT
CGAGAGATGCTTTGATCTGGAAAAGGGATAACATGAGGCTGCTGCATGTGGTACCTCCAGACTCTCCTGGCCGCTTCTGCCCCAAGGGAA
GGGACTCGGGGCAGAAGTTATTTATGATTCGTGACATTGTCCGCCCCAACCTTCTTGGCCCGCCGATCCTTGCCCCACCTGGTGACTTGC
GAGAGTGGTGCGGAGAGCCGCATTCCCCACAGCCAAGGCGTGACTGCAGGGTTCGAGTAGACTTTGCGGAGGGGACGGGGCAGCCCGCAG
ACTCCTGGGAGTGGTGCTGACGGGGGCTCTTTGTCATTCAACCTGTGGCTGCCAGCGTCCGCCGCAGCGCCCTTCTACTCATGGACTTAA
GGCGGCCCTGTTGAGAGAAATCTGGAGGATAGCGTTACACTTGGTCCGATGCAAGTTTTTTGTTCCAAATATTTGGATTTGACCTGCATT
TTGGAATTTATCTACACTTAAAATGCCACCAGCAGTTGGAGGTCCAGTTGGATACACCCCCCCAGATGGAGGCTGGGGCTGGGCAGTGGT
AATTGGAGCTTTCATTTCCATCGGCTTCTCTTATGCATTTCCCAAATCAATTACTGTCTTCTTCAAAGAGATTGAAGGTATATTCCATGC
CACCACCAGCGAAGTGTCATGGATATCCTCCATAATGTTGGCTGTCATGTATGGTGGAGCTTTGGCTAGATCAGAGTCTAAGAGAGATGG
AGGTTTTAAAAATAATTGGAGCTTTGATCATGAAGAAGAAAGTGAAGGAGATACAGATAAAGATGGGACAAATCTGCTCAGTGTGGATGA
AGATGAGGATTCTGAAACCTCAAAAGGAAAAAAGTTAAATCGTCGATCTGAAATTGTTGCTAATAGCTCTGGTGAATTCATCTTGAAGAC
ATATGTAAGACGAAACAAGTCTGAAAGTTTTAAAACTTTGAAAGGCAACCCAATTGGACTTAACATGTTGAGCAACAATAAGAAATTGAG
TGAAAATACGCAAAATACGTCATTATGTTCTGGAACTGTAGTTCATGGTAGACGTTTTCATCATGCTCATGCACAGATACCAGTAGTAAA
AACAGCAGCCCAAAGGAAAGAATACCCACCTCATGTCCAAAAAGTTGAAATTAATCCTGTAAGGTTAAGTCGGCTCCAAGGTGTTGAACG
TATAATGAAGAAAACAGAAGAGTCCGAATCACAAGTGGAGCCTGAAATTAAGAGGAAAGTACAACAGAAACGACACTGTAGTACCTATCA
GCCTACTCCTCCTCTATCTCCTGCTTCAAAAAAATGTTTAACCCATTTAGAGGATTTGCAAAGAAATTGCAGACAAGCTATTACTTTGAA
TGAGTCTACTGGACCATTATTAAGAACGTCAATTCATCAGAATTCTGGAGGACAGAAGTCACAAAACACAGGATTAACAACCAAGAAGTT
TTATGGCAACAATGTGGAAAAGGTTCCAATTGATATTATTGTGAATTGTGATGACAGTAAACACACTTATTTACAGACTAATGGAAAAGT
CATTTTACCTGGGGCAAAAATACCCAAAATCACAAACTTGAAAGAAAGGAAAACAAGTTTGTCAGACCTAAATGATCCAATCATTTTGTC
CAGTGATGATGATGATGACAACGACAGAACTAACAGAAGAGAAAGCATATCTCCTCAGCCTGCTGATTCAGCATGTTCTTCCCCTGCACC
ATCCACTGGAAAAGTAGAAGCAGCGCTAAATGAAAATACTTGCAGAGCAGAGCGTGAACTACGAAGCATTCCAGAAGACTCAGAGTTAAA
TACAGTTACATTGCCAAGAAAAGCAAGAATGAAAGACCAGTTTGGCAATTCTATTATCAACACACCTCTGAAACGTCGTAAAGTGTTTTC
TCAAGAACCTCCAGATGCTTTAGCTTTAAGCTGCCAAAGTTCCTTTGACAGTGTCATTTTAAACTGTCGAAGTATACGAGTAGGAACACT
CTTCCGGCTGTTAATAGAGCCTGTAATTTTTTGTTTAGATTTTATCAAGATACAGCTAGACGAACCAGACCATGATCCTGTAGAGATTAT
ATTAAATACCTCTGATCTAACTAAATGTGAATGGTGTAATGTCCGAAAATTACCTGTAGTGTTTCTTCAAGCAATTCCAGCAGTTTATCA
AAAGCTGAGCATCCAACTGCAAATGAATAAGGAGGATAAAGTTTGGAATGATTGTAAAGGAGTAAATAAATTAACAAATTTAGAAGAACA
ATATATAATTTTAATTTTTCAAAATGGCCTTGATCCTCCGGCAAATATGGTATTTGAAAGTATCATTAATGAAATTGGTATAAAGAATAA
CATCTCCAATTTTTTTGCGAAAATTCCCTTTGAAGAAGCTAATGGCAGACTTGTTGCCTGTACAAGAACCTATGAAGAGAGCATCAAAGG
AAGTTGTGGGCAAAAGGAAAACAAAATTAAAACTGTATCATTTGAATCTAAAATACAACTTAGAAGCAAACAAGAATTTCAGTTTTTTGA
TGAAGAAGAAGAAACTGGAGAAAACCACACCATCTTCATTGGCCCAGTAGAAAAGTTGATAGTATATCCACCACCTCCAGCTAAGGGAGG
CATCTCTGTTACCAATGAGGACCTGCACTGTCTAAATGAAGGAGAATTTTTAAATGATGTTATTATAGACTTTTATTTGAAATACTTGGT
GCTTGAAAAACTGAAGAAGGAAGACGCTGACCGAATTCATATATTCAGTTCTTTTTTCTATAAACGCCTTAATCAGAGAGAGAGGAGAAA
TCATGAAACAACTAATCTGTCAATACAGCAAAAACGGCATGGGAGAGTAAAAACATGGACCCGGCACGTAGATATTTTTGAGAAGGATTT
TATTTTTGTACCCCTTAATGAAGCTGCACACTGGTTTTTGGCTGTTGTTTGTTTCCCCGGTTTGGAAAAACCAAAGTATGAACCTAATCC
TCATTACCATGAAAATGCTGTCATACAGAAATGTTCAACTGTAGAGGACAGTTGTATTTCTTCTTCAGCCAGTGAAATGGAGAGTTGTTC
ACAAAACTCTTCTGCCAAGCCTGTAATTAAGAAGATGCTAAACAAAAAACATTGCATAGCTGTAATTGATTCCAATCCTGGGCAGGAAGA
AAGTGACCCTCGTTATAAGAGAAACATATGCAGTGTAAAATACAGTGTGAAAAAAATAAATCATACTGCGAGTGAAAATGAAGAATTCAA
TAAAGGAGAATCTACATCCCAGAAAGTTGCTGATAGGACTAAAAGTGAGAATGGCCTACAGAATGAAAGTTTAAGTTCCACACATCATAC
AGATGGCTTAAGCAAAATCAGACTAAACTATAGCGATGAATCACCTGAAGCTGGTAAAATGCTTGAAGATGAACTCGTCGACTTCTCAGA
AGATCAGGATAACCAGGATGATAGCAGTGACGATGGATTCCTCGCTGATGACAACTGCAGTTCAGAAATAGGACAGTGGCATTTAAAGCC
TACTATCTGTAAACAACCTTGTATCCTACTTATGGACTCACTCCGAGGCCCTTCTCGGTCAAATGTTGTCAAAATTTTAAGAGAGTATTT
AGAAGTGGAATGGGAAGTTAAAAAAGGAAGCAAAAGAAGTTTTTCCAAAGATGTTATGAAGGGCTCTAATCCAAAAGTACCACAGCAAAA
CAACTTCAGTGACTGTGGTGTATATGTATTGCAGTATGTAGAGAGCTTTTTTGAGAATCCAATTCTCAGTTTTGAACTACCTATGAATTT
GGCAAACTGGTTTCCTCCACCAAGAATGAGAACAAAAAGAGAAGAAATCCGAAACATAATTCTGAAGCTACAGGAAGATCAGAGCAAAGA
GAAAAGAAAGCATAAGGACACTTACTCAACAGAAGCACCTTTAGGCGAAGGAACAGAACAATATGTCAATAGTATCTCAGATTGACCATT
TCTGTTACTTGTCATTTCTACTTTCAGAAACTAAATGACTTTCAAATTTGGGTATAGACAATAAAGAACTGAAGTGCTCACTACTCAGTG
ATTTGGAAATTTTGATGCTTGTATAAATGTCAGATAATTAATTTCCAAAGGCGTATGTATTAAGTAAAAGTCTGTAAATATGTTAATGAG
GCCAATTTTTCCAGCATTTATAATTATTTTTTTCACTTGTTAGGAAGCTTTTGTTATGTATTTTCTGTTAATAGTACCTAAAATTGCAAC

>In-frame_ENST00000538576_ENST00000370010_TCGA-44-2668-01A_SLC16A1_chr1_113471714_-_SENP6_chr6_76331248_length(amino acids)=1160AA_start in transcript=832_stop in transcript=4314
MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIMLAVMYGGALARSESKRDGGFKNNWS
FDHEEESEGDTDKDGTNLLSVDEDEDSETSKGKKLNRRSEIVANSSGEFILKTYVRRNKSESFKTLKGNPIGLNMLSNNKKLSENTQNTS
LCSGTVVHGRRFHHAHAQIPVVKTAAQRKEYPPHVQKVEINPVRLSRLQGVERIMKKTEESESQVEPEIKRKVQQKRHCSTYQPTPPLSP
ASKKCLTHLEDLQRNCRQAITLNESTGPLLRTSIHQNSGGQKSQNTGLTTKKFYGNNVEKVPIDIIVNCDDSKHTYLQTNGKVILPGAKI
PKITNLKERKTSLSDLNDPIILSSDDDDDNDRTNRRESISPQPADSACSSPAPSTGKVEAALNENTCRAERELRSIPEDSELNTVTLPRK
ARMKDQFGNSIINTPLKRRKVFSQEPPDALALSCQSSFDSVILNCRSIRVGTLFRLLIEPVIFCLDFIKIQLDEPDHDPVEIILNTSDLT
KCEWCNVRKLPVVFLQAIPAVYQKLSIQLQMNKEDKVWNDCKGVNKLTNLEEQYIILIFQNGLDPPANMVFESIINEIGIKNNISNFFAK
IPFEEANGRLVACTRTYEESIKGSCGQKENKIKTVSFESKIQLRSKQEFQFFDEEEETGENHTIFIGPVEKLIVYPPPPAKGGISVTNED
LHCLNEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRNHETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNE
AAHWFLAVVCFPGLEKPKYEPNPHYHENAVIQKCSTVEDSCISSSASEMESCSQNSSAKPVIKKMLNKKHCIAVIDSNPGQEESDPRYKR
NICSVKYSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQNESLSSTHHTDGLSKIRLNYSDESPEAGKMLEDELVDFSEDQDNQDD
SSDDGFLADDNCSSEIGQWHLKPTICKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPKVPQQNNFSDCGV

--------------------------------------------------------------
>In-frame_ENST00000538576_ENST00000370014_TCGA-44-2668-01A_SLC16A1_chr1_113471714_-_SENP6_chr6_76331248_length(transcript)=7023nt_BP=1049nt
GCTCGGCGCTGCGATCCGCGCATATAACGGTTAGTTGGGTAACAGCCGGCGGCACGCGGCGCGGACCCCACGGTGCCCTCGCTGCCCTGG
TGGGGTCGGAGGGGACCTCCGGGGTTGGGAGACTTTGTCTCCGGCGGAGGGAGGCGGCCCAGCAGAGGGCATCGTGGTCACAGGCAGCCG
CGTGGCCTCGGACTGCAGTGCTGGTGAAGGAGACCTTGAGGCGCTGGGGTCAGCGCCTCTCTTAGCCGAGCCGCGGGCCCCGTGCTAAGA
TGCCGGTCCCAGGCCTGGCCGAGGAGTTGGGTCGTGGTGCCCGGTGACGGTGGGGAAGTCCCTTCCCCCCTAAGTCTTCAATAGGCTCCT
CGAGAGATGCTTTGATCTGGAAAAGGGATAACATGAGGCTGCTGCATGTGGTACCTCCAGACTCTCCTGGCCGCTTCTGCCCCAAGGGAA
GGGACTCGGGGCAGAAGTTATTTATGATTCGTGACATTGTCCGCCCCAACCTTCTTGGCCCGCCGATCCTTGCCCCACCTGGTGACTTGC
GAGAGTGGTGCGGAGAGCCGCATTCCCCACAGCCAAGGCGTGACTGCAGGGTTCGAGTAGACTTTGCGGAGGGGACGGGGCAGCCCGCAG
ACTCCTGGGAGTGGTGCTGACGGGGGCTCTTTGTCATTCAACCTGTGGCTGCCAGCGTCCGCCGCAGCGCCCTTCTACTCATGGACTTAA
GGCGGCCCTGTTGAGAGAAATCTGGAGGATAGCGTTACACTTGGTCCGATGCAAGTTTTTTGTTCCAAATATTTGGATTTGACCTGCATT
TTGGAATTTATCTACACTTAAAATGCCACCAGCAGTTGGAGGTCCAGTTGGATACACCCCCCCAGATGGAGGCTGGGGCTGGGCAGTGGT
AATTGGAGCTTTCATTTCCATCGGCTTCTCTTATGCATTTCCCAAATCAATTACTGTCTTCTTCAAAGAGATTGAAGGTATATTCCATGC
CACCACCAGCGAAGTGTCATGGATATCCTCCATAATGTTGGCTGTCATGTATGGTGGAGCTTTGGCTAGATCAGAGTCTAAGAGAGATGG
AGGTTTTAAAAATAATTGGAGCTTTGATCATGAAGAAGAAAGTGAAGGAGATACAGATAAAGATGGGACAAATCTGCTCAGTGTGGATGA
AGATGAGGATTCTGAAACCTCAAAAGGAAAAAAGTTAAATCGTCGATCTGAAATTGTTGCTAATAGCTCTGGTGAATTCATCTTGAAGAC
ATATGTAAGACGAAACAAGTCTGAAAGTTTTAAAACTTTGAAAGGCAACCCAATTGGACTTAACATGTTGAGCAACAATAAGAAATTGAG
TGAAAATACGCAAAATACGTCATTATGTTCTGGAACTGTAGTTCATGGTAGACGTTTTCATCATGCTCATGCACAGATACCAGTAGTAAA
AACAGCAGCCCAAAGGCTTTTGAGTAATCAGATTCTGAAAGAATACCCACCTCATGTCCAAAAAGTTGAAATTAATCCTGTAAGGTTAAG
TCGGCTCCAAGGTGTTGAACGTATAATGAAGAAAACAGAAGAGTCCGAATCACAAGTGGAGCCTGAAATTAAGAGGAAAGTACAACAGAA
ACGACACTGTAGTACCTATCAGCCTACTCCTCCTCTATCTCCTGCTTCAAAAAAATGTTTAACCCATTTAGAGGATTTGCAAAGAAATTG
CAGACAAGCTATTACTTTGAATGAGTCTACTGGACCATTATTAAGAACGTCAATTCATCAGAATTCTGGAGGACAGAAGTCACAAAACAC
AGGATTAACAACCAAGAAGTTTTATGGCAACAATGTGGAAAAGGTTCCAATTGATATTATTGTGAATTGTGATGACAGTAAACACACTTA
TTTACAGACTAATGGAAAAGTCATTTTACCTGGGGCAAAAATACCCAAAATCACAAACTTGAAAGAAAGGAAAACAAGTTTGTCAGACCT
AAATGATCCAATCATTTTGTCCAGTGATGATGATGATGACAACGACAGAACTAACAGAAGAGAAAGCATATCTCCTCAGCCTGCTGATTC
AGCATGTTCTTCCCCTGCACCATCCACTGGAAAAGTAGAAGCAGCGCTAAATGAAAATACTTGCAGAGCAGAGCGTGAACTACGAAGCAT
TCCAGAAGACTCAGAGTTAAATACAGTTACATTGCCAAGAAAAGCAAGAATGAAAGACCAGTTTGGCAATTCTATTATCAACACACCTCT
GAAACGTCGTAAAGTGTTTTCTCAAGAACCTCCAGATGCTTTAGCTTTAAGCTGCCAAAGTTCCTTTGACAGTGTCATTTTAAACTGTCG
AAGTATACGAGTAGGAACACTCTTCCGGCTGTTAATAGAGCCTGTAATTTTTTGTTTAGATTTTATCAAGATACAGCTAGACGAACCAGA
CCATGATCCTGTAGAGATTATATTAAATACCTCTGATCTAACTAAATGTGAATGGTGTAATGTCCGAAAATTACCTGTAGTGTTTCTTCA
AGCAATTCCAGCAGTTTATCAAAAGCTGAGCATCCAACTGCAAATGAATAAGGAGGATAAAGTTTGGAATGATTGTAAAGGAGTAAATAA
ATTAACAAATTTAGAAGAACAATATATAATTTTAATTTTTCAAAATGGCCTTGATCCTCCGGCAAATATGGTATTTGAAAGTATCATTAA
TGAAATTGGTATAAAGAATAACATCTCCAATTTTTTTGCGAAAATTCCCTTTGAAGAAGCTAATGGCAGACTTGTTGCCTGTACAAGAAC
CTATGAAGAGAGCATCAAAGGAAGTTGTGGGCAAAAGGAAAACAAAATTAAAACTGTATCATTTGAATCTAAAATACAACTTAGAAGCAA
ACAAGAATTTCAGTTTTTTGATGAAGAAGAAGAAACTGGAGAAAACCACACCATCTTCATTGGCCCAGTAGAAAAGTTGATAGTATATCC
ACCACCTCCAGCTAAGGGAGGCATCTCTGTTACCAATGAGGACCTGCACTGTCTAAATGAAGGAGAATTTTTAAATGATGTTATTATAGA
CTTTTATTTGAAATACTTGGTGCTTGAAAAACTGAAGAAGGAAGACGCTGACCGAATTCATATATTCAGTTCTTTTTTCTATAAACGCCT
TAATCAGAGAGAGAGGAGAAATCATGAAACAACTAATCTGTCAATACAGCAAAAACGGCATGGGAGAGTAAAAACATGGACCCGGCACGT
AGATATTTTTGAGAAGGATTTTATTTTTGTACCCCTTAATGAAGCTGCACACTGGTTTTTGGCTGTTGTTTGTTTCCCCGGTTTGGAAAA
ACCAAAGTATGAACCTAATCCTCATTACCATGAAAATGCTGTCATACAGAAATGTTCAACTGTAGAGGACAGTTGTATTTCTTCTTCAGC
CAGTGAAATGGAGAGTTGTTCACAAAACTCTTCTGCCAAGCCTGTAATTAAGAAGATGCTAAACAAAAAACATTGCATAGCTGTAATTGA
TTCCAATCCTGGGCAGGAAGAAAGTGACCCTCGTTATAAGAGAAACATATGCAGTGTAAAATACAGTGTGAAAAAAATAAATCATACTGC
GAGTGAAAATGAAGAATTCAATAAAGGAGAATCTACATCCCAGAAAGTTGCTGATAGGACTAAAAGTGAGAATGGCCTACAGAATGAAAG
TTTAAGTTCCACACATCATACAGATGGCTTAAGCAAAATCAGACTAAACTATAGCGATGAATCACCTGAAGCTGGTAAAATGCTTGAAGA
TGAACTCGTCGACTTCTCAGAAGATCAGGATAACCAGGATGATAGCAGTGACGATGGATTCCTCGCTGATGACAACTGCAGTTCAGAAAT
AGGACAGTGGCATTTAAAGCCTACTATCTGTAAACAACCTTGTATCCTACTTATGGACTCACTCCGAGGCCCTTCTCGGTCAAATGTTGT
CAAAATTTTAAGAGAGTATTTAGAAGTGGAATGGGAAGTTAAAAAAGGAAGCAAAAGAAGTTTTTCCAAAGATGTTATGAAGGGCTCTAA
TCCAAAAGTACCACAGCAAAACAACTTCAGTGACTGTGGTGTATATGTATTGCAGTATGTAGAGAGCTTTTTTGAGAATCCAATTCTCAG
TTTTGAACTACCTATGAATTTGGCAAACTGGTTTCCTCCACCAAGAATGAGAACAAAAAGAGAAGAAATCCGAAACATAATTCTGAAGCT
ACAGGAAGATCAGAGCAAAGAGAAAAGAAAGCATAAGGACACTTACTCAACAGAAGCACCTTTAGGCGAAGGAACAGAACAATATGTCAA
TAGTATCTCAGATTGACCATTTCTGTTACTTGTCATTTCTACTTTCAGAAACTAAATGACTTTCAAATTTGGGTATAGACAATAAAGAAC
TGAAGTGCTCACTACTCAGTGATTTGGAAATTTTGATGCTTGTATAAATGTCAGATAATTAATTTCCAAAGGCGTATGTATTAAGTAAAA
GTCTGTAAATATGTTAATGAGGCCAATTTTTCCAGCATTTATAATTATTTTTTTCACTTGTTAGGAAGCTTTTGTTATGTATTTTCTGTT
AATAGTACCTAAAATTGCAACTTCTAAACACAAATAAAAAGAAAATATTTATAGGAGGAAATGATTAATTTGATATTCTTTAGTGAACTT
GTTTAATTCCTCAGTGGGTGTGACATATTTCATGGGAATATTCAAATATCTATGGTAATATTTTGACCCTTTATATTTGTTCTAAAATAA
GTCAAAATGTGAAAATAATATTAAATCTAAGATATTTTGAACTAAGCATCTTTATATGCTTGTGTAACAGGAACAAAGTAACAGCCTTTC
AATTCATATACTGCCTTGTGTTCAGTGAACCCAAGAAATGTAATAAATATTTGTAATTTTACACAAATATTTAAGAGGAAAGAGTATTAA
GAGCAATTCAAAAAAAGTAACCTTATACTACTAAAAAAAAAATTCTTGCATATATTATCATCAAATGCATTTTTGAAGACATCAAAGACT
CAGGTTAAAACTATTTTGGTAAGTGCAGCTTGAATTTCAAATATCCCGTGTTACCTTTCTCTATTACAGCTTAAAGTATGCTACAATCTG
TGTCATATAGTTAATTGATAAGCATTTTTAATCTGTGTAAACACAGGAATTTAAATAGGAATTTACTATTTTTTTATAAAGCTTTTGCTA
TTTTTTCATTGCTCATTTTGTTCTTATTATTTTGATAAAGTATCAGACTTTTTGCTTGAGTTCTTCAGTGTAAATTATTTTTTACATGTA
AAAGTACTGTATTCAACCAGTTGCATAATACAGCAAAAATCTTTGAATTCCCCTTTAAAATAACTAAAATTTGATGGTTTCCATGACAGA
TTTATAGCACATATAGGGATCTTGCATGTATCTGCAGAAACTTCATTATTTTTCAAATGAAATGGTGTATACTTCTTTCAAATGAACTTT
GAGACTTGAAACATATTTTAGTCATTTTTTGTTAAATATTGAATTTTTAAATACACATATATCAAAAATAGTTGAGAATAAAAAGAAAGC
CTAATCATCAGCAATTATTTTATTTTTAATTTGGCCATCTCTGACATTGCAGTCAATATCTTAGGGTATTTTCTTGAATTTAATAAAGTC
CCATGGGTGGGTTCAGGGTGAATGGGAGTATTAACAACAACCAAAAAATATCTATTGAGACACAGTAGAGTCTCAGTAAGAGAAATATTA
AAATGTAAGAAAGGTCACCATTAGTGATATCAACTGTAGTTTGTTACTTTGAACTATATTTCTGATTAACTCTTTATAGTAATAACTTAG
AGCTGTTAGCTCAGATATCTTAATTAGCTCATATGAAAAACAAGTTTAATTTTATTATTTACTGAACATGGCAAAATGCTTTTCAATCTA
TAATAAAACTGGGATAAAAAATTGAAGTTGTTTTTTTTAAAACCTAATAGCAATAAGCAAAATTGGCATACATAATTTTTTTAATGAACT
ATATTTTGTCAGAATCTGAAGGTACTGAAAAACTATTCTAAAATGCCTACTTGTTTTTGCATTAATTTGTAATGCTTACATTTTGCACCC
TTAGATAATGTTTGATAAGATAAAAATATAATTTATCCCTTGTACCAACTCAAGTCAATCAGATTTTAACATGAAAAATATAGATTAATG
TATGTCAGCTTTCTAGAGGTAGAATACTCAGCTATTTGATGGCATTTTTCCCACCCCATGTGAAATTTTATTTTTGGAAGTTATGCTAGT
GACATTGCAATATATATTGAAATCTTCGGAGGCTGCCAGGTTGAGCTTCAAAACTAGACTTGAGAATCTTTCGTGTATATGCACATTCAC
TTGATAATTGTGTATTCTATGTAGTTTAAAGTGGGATCAAGCCTTTTAAAATGTGTTATTAGTACTTAGAAGTTGTAAAACAGAACTTAT
AGAGGTTTGTTACTAGACACTGAAACTGCATGACAAGTATCTGGTGTCTTAACTAATTAGATAGATCTGTTGTATTGGTTTTCTTGTTGG
ATAGAATAACAGTTAATCATTTTTAGAAGAGTTTTAGATTACTTGCCATAAAATTTGTATGTCTCAGCTCTTGTTGGTTTAGGAGCAGAA
GTGGTGTTTAGTCCCTTCCCGTTAATGTTGCTGTGCTACTTCAGACAGCTGAAAACTTAATGGTATTATTTCAAGTTCACATAACCCTAA
AAAAGGTTTTCTTTGTGTAGTAACTTGTGCTTAAACTTTTAGTCAATTAAATGTAGGAGGTTTTATTTGAAAACATAAAATGATTCTCTA
AATTACATCTTGTTTTAAGCCACCAAAATGAATGCAGTAATTTTTCTTTAAAAAAATGATCTCTGAAAACTGTGAGACAATGTAAAAAGA
ATAAGTTTTAATTCCCCCAAAATCAAAAATTGTACTTAAAATCTCAGACAATTCACTGAACAGGAATAATAAAGAACATATTTTAATATA

>In-frame_ENST00000538576_ENST00000370014_TCGA-44-2668-01A_SLC16A1_chr1_113471714_-_SENP6_chr6_76331248_length(amino acids)=1167AA_start in transcript=832_stop in transcript=4335
MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIMLAVMYGGALARSESKRDGGFKNNWS
FDHEEESEGDTDKDGTNLLSVDEDEDSETSKGKKLNRRSEIVANSSGEFILKTYVRRNKSESFKTLKGNPIGLNMLSNNKKLSENTQNTS
LCSGTVVHGRRFHHAHAQIPVVKTAAQRLLSNQILKEYPPHVQKVEINPVRLSRLQGVERIMKKTEESESQVEPEIKRKVQQKRHCSTYQ
PTPPLSPASKKCLTHLEDLQRNCRQAITLNESTGPLLRTSIHQNSGGQKSQNTGLTTKKFYGNNVEKVPIDIIVNCDDSKHTYLQTNGKV
ILPGAKIPKITNLKERKTSLSDLNDPIILSSDDDDDNDRTNRRESISPQPADSACSSPAPSTGKVEAALNENTCRAERELRSIPEDSELN
TVTLPRKARMKDQFGNSIINTPLKRRKVFSQEPPDALALSCQSSFDSVILNCRSIRVGTLFRLLIEPVIFCLDFIKIQLDEPDHDPVEII
LNTSDLTKCEWCNVRKLPVVFLQAIPAVYQKLSIQLQMNKEDKVWNDCKGVNKLTNLEEQYIILIFQNGLDPPANMVFESIINEIGIKNN
ISNFFAKIPFEEANGRLVACTRTYEESIKGSCGQKENKIKTVSFESKIQLRSKQEFQFFDEEEETGENHTIFIGPVEKLIVYPPPPAKGG
ISVTNEDLHCLNEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRNHETTNLSIQQKRHGRVKTWTRHVDIFEKDF
IFVPLNEAAHWFLAVVCFPGLEKPKYEPNPHYHENAVIQKCSTVEDSCISSSASEMESCSQNSSAKPVIKKMLNKKHCIAVIDSNPGQEE
SDPRYKRNICSVKYSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQNESLSSTHHTDGLSKIRLNYSDESPEAGKMLEDELVDFSE
DQDNQDDSSDDGFLADDNCSSEIGQWHLKPTICKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPKVPQQN

--------------------------------------------------------------
>In-frame_ENST00000538576_ENST00000447266_TCGA-44-2668-01A_SLC16A1_chr1_113471714_-_SENP6_chr6_76331248_length(transcript)=7020nt_BP=1049nt
GCTCGGCGCTGCGATCCGCGCATATAACGGTTAGTTGGGTAACAGCCGGCGGCACGCGGCGCGGACCCCACGGTGCCCTCGCTGCCCTGG
TGGGGTCGGAGGGGACCTCCGGGGTTGGGAGACTTTGTCTCCGGCGGAGGGAGGCGGCCCAGCAGAGGGCATCGTGGTCACAGGCAGCCG
CGTGGCCTCGGACTGCAGTGCTGGTGAAGGAGACCTTGAGGCGCTGGGGTCAGCGCCTCTCTTAGCCGAGCCGCGGGCCCCGTGCTAAGA
TGCCGGTCCCAGGCCTGGCCGAGGAGTTGGGTCGTGGTGCCCGGTGACGGTGGGGAAGTCCCTTCCCCCCTAAGTCTTCAATAGGCTCCT
CGAGAGATGCTTTGATCTGGAAAAGGGATAACATGAGGCTGCTGCATGTGGTACCTCCAGACTCTCCTGGCCGCTTCTGCCCCAAGGGAA
GGGACTCGGGGCAGAAGTTATTTATGATTCGTGACATTGTCCGCCCCAACCTTCTTGGCCCGCCGATCCTTGCCCCACCTGGTGACTTGC
GAGAGTGGTGCGGAGAGCCGCATTCCCCACAGCCAAGGCGTGACTGCAGGGTTCGAGTAGACTTTGCGGAGGGGACGGGGCAGCCCGCAG
ACTCCTGGGAGTGGTGCTGACGGGGGCTCTTTGTCATTCAACCTGTGGCTGCCAGCGTCCGCCGCAGCGCCCTTCTACTCATGGACTTAA
GGCGGCCCTGTTGAGAGAAATCTGGAGGATAGCGTTACACTTGGTCCGATGCAAGTTTTTTGTTCCAAATATTTGGATTTGACCTGCATT
TTGGAATTTATCTACACTTAAAATGCCACCAGCAGTTGGAGGTCCAGTTGGATACACCCCCCCAGATGGAGGCTGGGGCTGGGCAGTGGT
AATTGGAGCTTTCATTTCCATCGGCTTCTCTTATGCATTTCCCAAATCAATTACTGTCTTCTTCAAAGAGATTGAAGGTATATTCCATGC
CACCACCAGCGAAGTGTCATGGATATCCTCCATAATGTTGGCTGTCATGTATGGTGGAGCTTTGGCTAGATCAGAGTCTAAGAGAGATGG
AGGTTTTAAAAATAATTGGAGCTTTGATCATGAAGAAGAAAGTGAAGGAGATACAGATAAAGATGGGACAAATCTGCTCAGTGTGGATGA
AGATGAGGATTCTGAAACCTCAAAAGGAAAAAAGTTAAATCGTCGATCTGAAATTGTTGCTAATAGCTCTGGTGAATTCATCTTGAAGAC
ATATGTAAGACGAAACAAGTCTGAAAGTTTTAAAACTTTGAAAGGCAACCCAATTGGACTTAACATGTTGAGCAACAATAAGAAATTGAG
TGAAAATACGCAAAATACGTCATTATGTTCTGGAACTGTAGTTCATGGTAGACGTTTTCATCATGCTCATGCACAGATACCAGTAGTAAA
AACAGCAGCCCAAAGCAGTCTGGACCGAAAAGAAAGGAAAGAATACCCACCTCATGTCCAAAAAGTTGAAATTAATCCTGTAAGGTTAAG
TCGGCTCCAAGGTGTTGAACGTATAATGAAGAAAACAGAAGAGTCCGAATCACAAGTGGAGCCTGAAATTAAGAGGAAAGTACAACAGAA
ACGACACTGTAGTACCTATCAGCCTACTCCTCCTCTATCTCCTGCTTCAAAAAAATGTTTAACCCATTTAGAGGATTTGCAAAGAAATTG
CAGACAAGCTATTACTTTGAATGAGTCTACTGGACCATTATTAAGAACGTCAATTCATCAGAATTCTGGAGGACAGAAGTCACAAAACAC
AGGATTAACAACCAAGAAGTTTTATGGCAACAATGTGGAAAAGGTTCCAATTGATATTATTGTGAATTGTGATGACAGTAAACACACTTA
TTTACAGACTAATGGAAAAGTCATTTTACCTGGGGCAAAAATACCCAAAATCACAAACTTGAAAGAAAGGAAAACAAGTTTGTCAGACCT
AAATGATCCAATCATTTTGTCCAGTGATGATGATGATGACAACGACAGAACTAACAGAAGAGAAAGCATATCTCCTCAGCCTGCTGATTC
AGCATGTTCTTCCCCTGCACCATCCACTGGAAAAGTAGAAGCAGCGCTAAATGAAAATACTTGCAGAGCAGAGCGTGAACTACGAAGCAT
TCCAGAAGACTCAGAGTTAAATACAGTTACATTGCCAAGAAAAGCAAGAATGAAAGACCAGTTTGGCAATTCTATTATCAACACACCTCT
GAAACGTCGTAAAGTGTTTTCTCAAGAACCTCCAGATGCTTTAGCTTTAAGCTGCCAAAGTTCCTTTGACAGTGTCATTTTAAACTGTCG
AAGTATACGAGTAGGAACACTCTTCCGGCTGTTAATAGAGCCTGTAATTTTTTGTTTAGATTTTATCAAGATACAGCTAGACGAACCAGA
CCATGATCCTGTAGAGATTATATTAAATACCTCTGATCTAACTAAATGTGAATGGTGTAATGTCCGAAAATTACCTGTAGTGTTTCTTCA
AGCAATTCCAGCAGTTTATCAAAAGCTGAGCATCCAACTGCAAATGAATAAGGAGGATAAAGTTTGGAATGATTGTAAAGGAGTAAATAA
ATTAACAAATTTAGAAGAACAATATATAATTTTAATTTTTCAAAATGGCCTTGATCCTCCGGCAAATATGGTATTTGAAAGTATCATTAA
TGAAATTGGTATAAAGAATAACATCTCCAATTTTTTTGCGAAAATTCCCTTTGAAGAAGCTAATGGCAGACTTGTTGCCTGTACAAGAAC
CTATGAAGAGAGCATCAAAGGAAGTTGTGGGCAAAAGGAAAACAAAATTAAAACTGTATCATTTGAATCTAAAATACAACTTAGAAGCAA
ACAAGAATTTCAGTTTTTTGATGAAGAAGAAGAAACTGGAGAAAACCACACCATCTTCATTGGCCCAGTAGAAAAGTTGATAGTATATCC
ACCACCTCCAGCTAAGGGAGGCATCTCTGTTACCAATGAGGACCTGCACTGTCTAAATGAAGGAGAATTTTTAAATGATGTTATTATAGA
CTTTTATTTGAAATACTTGGTGCTTGAAAAACTGAAGAAGGAAGACGCTGACCGAATTCATATATTCAGTTCTTTTTTCTATAAACGCCT
TAATCAGAGAGAGAGGAGAAATCATGAAACAACTAATCTGTCAATACAGCAAAAACGGCATGGGAGAGTAAAAACATGGACCCGGCACGT
AGATATTTTTGAGAAGGATTTTATTTTTGTACCCCTTAATGAAGCTGCACACTGGTTTTTGGCTGTTGTTTGTTTCCCCGGTTTGGAAAA
ACCAAAGTATGAACCTAATCCTCATTACCATGAAAATGCTGTCATACAGAAATGTTCAACTGTAGAGGACAGTTGTATTTCTTCTTCAGC
CAGTGAAATGGAGAGTTGTTCACAAAACTCTTCTGCCAAGCCTGTAATTAAGAAGATGCTAAACAAAAAACATTGCATAGCTGTAATTGA
TTCCAATCCTGGGCAGGAAGAAAGTGACCCTCGTTATAAGAGAAACATATGCAGTGTAAAATACAGTGTGAAAAAAATAAATCATACTGC
GAGTGAAAATGAAGAATTCAATAAAGGAGAATCTACATCCCAGAAAGTTGCTGATAGGACTAAAAGTGAGAATGGCCTACAGAATGAAAG
TTTAAGTTCCACACATCATACAGATGGCTTAAGCAAAATCAGACTAAACTATAGCGATGAATCACCTGAAGCTGGTAAAATGCTTGAAGA
TGAACTCGTCGACTTCTCAGAAGATCAGGATAACCAGGATGATAGCAGTGACGATGGATTCCTCGCTGATGACAACTGCAGTTCAGAAAT
AGGACAGTGGCATTTAAAGCCTACTATCTGTAAACAACCTTGTATCCTACTTATGGACTCACTCCGAGGCCCTTCTCGGTCAAATGTTGT
CAAAATTTTAAGAGAGTATTTAGAAGTGGAATGGGAAGTTAAAAAAGGAAGCAAAAGAAGTTTTTCCAAAGATGTTATGAAGGGCTCTAA
TCCAAAAGTACCACAGCAAAACAACTTCAGTGACTGTGGTGTATATGTATTGCAGTATGTAGAGAGCTTTTTTGAGAATCCAATTCTCAG
TTTTGAACTACCTATGAATTTGGCAAACTGGTTTCCTCCACCAAGAATGAGAACAAAAAGAGAAGAAATCCGAAACATAATTCTGAAGCT
ACAGGAAGATCAGAGCAAAGAGAAAAGAAAGCATAAGGACACTTACTCAACAGAAGCACCTTTAGGCGAAGGAACAGAACAATATGTCAA
TAGTATCTCAGATTGACCATTTCTGTTACTTGTCATTTCTACTTTCAGAAACTAAATGACTTTCAAATTTGGGTATAGACAATAAAGAAC
TGAAGTGCTCACTACTCAGTGATTTGGAAATTTTGATGCTTGTATAAATGTCAGATAATTAATTTCCAAAGGCGTATGTATTAAGTAAAA
GTCTGTAAATATGTTAATGAGGCCAATTTTTCCAGCATTTATAATTATTTTTTTCACTTGTTAGGAAGCTTTTGTTATGTATTTTCTGTT
AATAGTACCTAAAATTGCAACTTCTAAACACAAATAAAAAGAAAATATTTATAGGAGGAAATGATTAATTTGATATTCTTTAGTGAACTT
GTTTAATTCCTCAGTGGGTGTGACATATTTCATGGGAATATTCAAATATCTATGGTAATATTTTGACCCTTTATATTTGTTCTAAAATAA
GTCAAAATGTGAAAATAATATTAAATCTAAGATATTTTGAACTAAGCATCTTTATATGCTTGTGTAACAGGAACAAAGTAACAGCCTTTC
AATTCATATACTGCCTTGTGTTCAGTGAACCCAAGAAATGTAATAAATATTTGTAATTTTACACAAATATTTAAGAGGAAAGAGTATTAA
GAGCAATTCAAAAAAAGTAACCTTATACTACTAAAAAAAAAATTCTTGCATATATTATCATCAAATGCATTTTTGAAGACATCAAAGACT
CAGGTTAAAACTATTTTGGTAAGTGCAGCTTGAATTTCAAATATCCCGTGTTACCTTTCTCTATTACAGCTTAAAGTATGCTACAATCTG
TGTCATATAGTTAATTGATAAGCATTTTTAATCTGTGTAAACACAGGAATTTAAATAGGAATTTACTATTTTTTTATAAAGCTTTTGCTA
TTTTTTCATTGCTCATTTTGTTCTTATTATTTTGATAAAGTATCAGACTTTTTGCTTGAGTTCTTCAGTGTAAATTATTTTTTACATGTA
AAAGTACTGTATTCAACCAGTTGCATAATACAGCAAAAATCTTTGAATTCCCCTTTAAAATAACTAAAATTTGATGGTTTCCATGACAGA
TTTATAGCACATATAGGGATCTTGCATGTATCTGCAGAAACTTCATTATTTTTCAAATGAAATGGTGTATACTTCTTTCAAATGAACTTT
GAGACTTGAAACATATTTTAGTCATTTTTTGTTAAATATTGAATTTTTAAATACACATATATCAAAAATAGTTGAGAATAAAAAGAAAGC
CTAATCATCAGCAATTATTTTATTTTTAATTTGGCCATCTCTGACATTGCAGTCAATATCTTAGGGTATTTTCTTGAATTTAATAAAGTC
CCATGGGTGGGTTCAGGGTGAATGGGAGTATTAACAACAACCAAAAAATATCTATTGAGACACAGTAGAGTCTCAGTAAGAGAAATATTA
AAATGTAAGAAAGGTCACCATTAGTGATATCAACTGTAGTTTGTTACTTTGAACTATATTTCTGATTAACTCTTTATAGTAATAACTTAG
AGCTGTTAGCTCAGATATCTTAATTAGCTCATATGAAAAACAAGTTTAATTTTATTATTTACTGAACATGGCAAAATGCTTTTCAATCTA
TAATAAAACTGGGATAAAAAATTGAAGTTGTTTTTTTTAAAACCTAATAGCAATAAGCAAAATTGGCATACATAATTTTTTTAATGAACT
ATATTTTGTCAGAATCTGAAGGTACTGAAAAACTATTCTAAAATGCCTACTTGTTTTTGCATTAATTTGTAATGCTTACATTTTGCACCC
TTAGATAATGTTTGATAAGATAAAAATATAATTTATCCCTTGTACCAACTCAAGTCAATCAGATTTTAACATGAAAAATATAGATTAATG
TATGTCAGCTTTCTAGAGGTAGAATACTCAGCTATTTGATGGCATTTTTCCCACCCCATGTGAAATTTTATTTTTGGAAGTTATGCTAGT
GACATTGCAATATATATTGAAATCTTCGGAGGCTGCCAGGTTGAGCTTCAAAACTAGACTTGAGAATCTTTCGTGTATATGCACATTCAC
TTGATAATTGTGTATTCTATGTAGTTTAAAGTGGGATCAAGCCTTTTAAAATGTGTTATTAGTACTTAGAAGTTGTAAAACAGAACTTAT
AGAGGTTTGTTACTAGACACTGAAACTGCATGACAAGTATCTGGTGTCTTAACTAATTAGATAGATCTGTTGTATTGGTTTTCTTGTTGG
ATAGAATAACAGTTAATCATTTTTAGAAGAGTTTTAGATTACTTGCCATAAAATTTGTATGTCTCAGCTCTTGTTGGTTTAGGAGCAGAA
GTGGTGTTTAGTCCCTTCCCGTTAATGTTGCTGTGCTACTTCAGACAGCTGAAAACTTAATGGTATTATTTCAAGTTCACATAACCCTAA
AAAAGGTTTTCTTTGTGTAGTAACTTGTGCTTAAACTTTTAGTCAATTAAATGTAGGAGGTTTTATTTGAAAACATAAAATGATTCTCTA
AATTACATCTTGTTTTAAGCCACCAAAATGAATGCAGTAATTTTTCTTTAAAAAAATGATCTCTGAAAACTGTGAGACAATGTAAAAAGA
ATAAGTTTTAATTCCCCCAAAATCAAAAATTGTACTTAAAATCTCAGACAATTCACTGAACAGGAATAATAAAGAACATATTTTAATATA

>In-frame_ENST00000538576_ENST00000447266_TCGA-44-2668-01A_SLC16A1_chr1_113471714_-_SENP6_chr6_76331248_length(amino acids)=1167AA_start in transcript=832_stop in transcript=4335
MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIMLAVMYGGALARSESKRDGGFKNNWS
FDHEEESEGDTDKDGTNLLSVDEDEDSETSKGKKLNRRSEIVANSSGEFILKTYVRRNKSESFKTLKGNPIGLNMLSNNKKLSENTQNTS
LCSGTVVHGRRFHHAHAQIPVVKTAAQSSLDRKERKEYPPHVQKVEINPVRLSRLQGVERIMKKTEESESQVEPEIKRKVQQKRHCSTYQ
PTPPLSPASKKCLTHLEDLQRNCRQAITLNESTGPLLRTSIHQNSGGQKSQNTGLTTKKFYGNNVEKVPIDIIVNCDDSKHTYLQTNGKV
ILPGAKIPKITNLKERKTSLSDLNDPIILSSDDDDDNDRTNRRESISPQPADSACSSPAPSTGKVEAALNENTCRAERELRSIPEDSELN
TVTLPRKARMKDQFGNSIINTPLKRRKVFSQEPPDALALSCQSSFDSVILNCRSIRVGTLFRLLIEPVIFCLDFIKIQLDEPDHDPVEII
LNTSDLTKCEWCNVRKLPVVFLQAIPAVYQKLSIQLQMNKEDKVWNDCKGVNKLTNLEEQYIILIFQNGLDPPANMVFESIINEIGIKNN
ISNFFAKIPFEEANGRLVACTRTYEESIKGSCGQKENKIKTVSFESKIQLRSKQEFQFFDEEEETGENHTIFIGPVEKLIVYPPPPAKGG
ISVTNEDLHCLNEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRNHETTNLSIQQKRHGRVKTWTRHVDIFEKDF
IFVPLNEAAHWFLAVVCFPGLEKPKYEPNPHYHENAVIQKCSTVEDSCISSSASEMESCSQNSSAKPVIKKMLNKKHCIAVIDSNPGQEE
SDPRYKRNICSVKYSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQNESLSSTHHTDGLSKIRLNYSDESPEAGKMLEDELVDFSE
DQDNQDDSSDDGFLADDNCSSEIGQWHLKPTICKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPKVPQQN

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SLC16A1-SENP6


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SLC16A1-SENP6


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SLC16A1-SENP6


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneSLC16A1C1855577Erythrocyte Lactate Transporter Defect2CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
HgeneSLC16A1C0007102Malignant tumor of colon1CTD_human
HgeneSLC16A1C0007621Neoplastic Cell Transformation1CTD_human
HgeneSLC16A1C0009375Colonic Neoplasms1CTD_human
HgeneSLC16A1C1864902Hyperinsulinemic hypoglycemia, familial, 71CTD_human;GENOMICS_ENGLAND;ORPHANET
HgeneSLC16A1C4015186MONOCARBOXYLATE TRANSPORTER 1 DEFICIENCY1CTD_human;ORPHANET;UNIPROT
TgeneSENP6C0033578Prostatic Neoplasms1CTD_human
TgeneSENP6C0376358Malignant neoplasm of prostate1CTD_human