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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SLC25A13-CD2AP (FusionGDB2 ID:81978)

Fusion Gene Summary for SLC25A13-CD2AP

check button Fusion gene summary
Fusion gene informationFusion gene name: SLC25A13-CD2AP
Fusion gene ID: 81978
HgeneTgene
Gene symbol

SLC25A13

CD2AP

Gene ID

10165

23607

Gene namesolute carrier family 25 member 13CD2 associated protein
SynonymsARALAR2|CITRIN|CTLN2|NICCDCMS
Cytomap

7q21.3

6p12.3

Type of geneprotein-codingprotein-coding
Descriptioncalcium-binding mitochondrial carrier protein Aralar2mitochondrial aspartate glutamate carrier 2solute carrier family 25 (aspartate/glutamate carrier), member 13CD2-associated proteinCas ligand with multiple Src homology 3 (SH3) domainsadapter protein CMScas ligand with multiple SH3 domains
Modification date2020031320200327
UniProtAcc.

Q9Y5K6

Ensembl transtripts involved in fusion geneENST00000265631, ENST00000416240, 
ENST00000542654, ENST00000494085, 
ENST00000359314, ENST00000486693, 
Fusion gene scores* DoF score17 X 13 X 11=243112 X 12 X 8=1152
# samples 1714
** MAII scorelog2(17/2431*10)=-3.83794324189103
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(14/1152*10)=-3.04064198449735
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SLC25A13 [Title/Abstract] AND CD2AP [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCD2AP(47501491)-SLC25A13(95800836), # samples:4
SLC25A13(95813589)-CD2AP(47512342), # samples:3
Anticipated loss of major functional domain due to fusion event.SLC25A13-CD2AP seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
SLC25A13-CD2AP seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSLC25A13

GO:0006754

ATP biosynthetic process

12851387

HgeneSLC25A13

GO:0015810

aspartate transmembrane transport

11566871

HgeneSLC25A13

GO:0015813

L-glutamate transmembrane transport

11566871

HgeneSLC25A13

GO:0043490

malate-aspartate shuttle

11566871

HgeneSLC25A13

GO:0045333

cellular respiration

12851387

HgeneSLC25A13

GO:0051592

response to calcium ion

11566871


check buttonFusion gene breakpoints across SLC25A13 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across CD2AP (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4READTCGA-EI-6510-01ASLC25A13chr7

95813589

-CD2APchr6

47512342

+
ChimerDB4READTCGA-EI-6510SLC25A13chr7

95813589

-CD2APchr6

47512342

+
ChimerDB4READTCGA-EI-6510-01ASLC25A13chr7

95813589

-CD2APchr6

47512342

+


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Fusion Gene ORF analysis for SLC25A13-CD2AP

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000265631ENST00000359314SLC25A13chr7

95813589

-CD2APchr6

47512342

+
5CDS-intronENST00000265631ENST00000486693SLC25A13chr7

95813589

-CD2APchr6

47512342

+
In-frameENST00000416240ENST00000359314SLC25A13chr7

95813589

-CD2APchr6

47512342

+
5CDS-intronENST00000416240ENST00000486693SLC25A13chr7

95813589

-CD2APchr6

47512342

+
Frame-shiftENST00000542654ENST00000359314SLC25A13chr7

95813589

-CD2APchr6

47512342

+
5CDS-intronENST00000542654ENST00000486693SLC25A13chr7

95813589

-CD2APchr6

47512342

+
intron-3CDSENST00000494085ENST00000359314SLC25A13chr7

95813589

-CD2APchr6

47512342

+
intron-intronENST00000494085ENST00000486693SLC25A13chr7

95813589

-CD2APchr6

47512342

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000265631SLC25A13chr795813589-ENST00000359314CD2APchr647512342+595113141372914925
ENST00000416240SLC25A13chr795813589-ENST00000359314CD2APchr647512342+600813711912971926

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000265631ENST00000359314SLC25A13chr795813589-CD2APchr647512342+8.14E-050.9999187
ENST00000416240ENST00000359314SLC25A13chr795813589-CD2APchr647512342+8.86E-050.9999113

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Fusion Genomic Features for SLC25A13-CD2AP


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SLC25A13chr795813588-CD2APchr647512341+8.61E-080.9999999
SLC25A13chr795813588-CD2APchr647512341+8.61E-080.9999999
SLC25A13chr795813588-CD2APchr647512341+8.61E-080.9999999
SLC25A13chr795813588-CD2APchr647512341+8.61E-080.9999999

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SLC25A13-CD2AP


check button Go to

FGviewer for the breakpoints of chr7:95813589-chr6:47512342

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CD2AP

Q9Y5K6

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton (PubMed:10339567). In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation (By similarity). May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell (By similarity). May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis (PubMed:15800069). Plays a role in epithelial cell junctions formation (PubMed:22891260). {ECO:0000250|UniProtKB:F1LRS8, ECO:0000250|UniProtKB:Q9JLQ0, ECO:0000269|PubMed:10339567, ECO:0000269|PubMed:15800069, ECO:0000269|PubMed:22891260}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118100_111392.3333333333333676.0Calcium bindingNote=2
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118171_182392.3333333333333676.0Calcium bindingNote=3
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-111866_77392.3333333333333676.0Calcium binding1
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118100_111393.3333333333333677.0Calcium bindingNote=2
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118171_182393.3333333333333677.0Calcium bindingNote=3
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-111866_77393.3333333333333677.0Calcium binding1
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118125_157392.3333333333333676.0DomainEF-hand 3
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118158_193392.3333333333333676.0DomainEF-hand 4
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-111851_86392.3333333333333676.0DomainEF-hand 1
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-111887_122392.3333333333333676.0DomainEF-hand 2
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118125_157393.3333333333333677.0DomainEF-hand 3
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118158_193393.3333333333333677.0DomainEF-hand 4
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-111851_86393.3333333333333677.0DomainEF-hand 1
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-111887_122393.3333333333333677.0DomainEF-hand 2
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118296_311392.3333333333333676.0RegionLinker loop domain
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-11182_295392.3333333333333676.0RegionN-terminal domain
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118296_311393.3333333333333677.0RegionLinker loop domain
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-11182_295393.3333333333333677.0RegionN-terminal domain
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118332_349392.3333333333333676.0TransmembraneHelical%3B Name%3D1
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118332_349393.3333333333333677.0TransmembraneHelical%3B Name%3D1
TgeneCD2APchr7:95813589chr6:47512342ENST00000359314218577_638106.33333333333333640.0Coiled coilOntology_term=ECO:0000255
TgeneCD2APchr7:95813589chr6:47512342ENST00000359314218336_422106.33333333333333640.0Compositional biasNote=Pro-rich
TgeneCD2APchr7:95813589chr6:47512342ENST00000359314218108_167106.33333333333333640.0DomainSH3 2
TgeneCD2APchr7:95813589chr6:47512342ENST00000359314218269_330106.33333333333333640.0DomainSH3 3
TgeneCD2APchr7:95813589chr6:47512342ENST00000359314218336_352106.33333333333333640.0MotifSH3-binding
TgeneCD2APchr7:95813589chr6:47512342ENST00000359314218378_397106.33333333333333640.0MotifSH3-binding
TgeneCD2APchr7:95813589chr6:47512342ENST00000359314218410_422106.33333333333333640.0MotifSH3-binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118321_612392.3333333333333676.0RegionCarrier domain
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118613_675392.3333333333333676.0RegionC-terminal domain
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118321_612393.3333333333333677.0RegionCarrier domain
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118613_675393.3333333333333677.0RegionC-terminal domain
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118326_418392.3333333333333676.0RepeatSolcar 1
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118426_510392.3333333333333676.0RepeatSolcar 2
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118518_606392.3333333333333676.0RepeatSolcar 3
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118326_418393.3333333333333677.0RepeatSolcar 1
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118426_510393.3333333333333677.0RepeatSolcar 2
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118518_606393.3333333333333677.0RepeatSolcar 3
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118393_412392.3333333333333676.0TransmembraneHelical%3B Name%3D2
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118436_449392.3333333333333676.0TransmembraneHelical%3B Name%3D3
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118485_504392.3333333333333676.0TransmembraneHelical%3B Name%3D4
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118524_541392.3333333333333676.0TransmembraneHelical%3B Name%3D5
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118581_600392.3333333333333676.0TransmembraneHelical%3B Name%3D6
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118393_412393.3333333333333677.0TransmembraneHelical%3B Name%3D2
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118436_449393.3333333333333677.0TransmembraneHelical%3B Name%3D3
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118485_504393.3333333333333677.0TransmembraneHelical%3B Name%3D4
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118524_541393.3333333333333677.0TransmembraneHelical%3B Name%3D5
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118581_600393.3333333333333677.0TransmembraneHelical%3B Name%3D6
TgeneCD2APchr7:95813589chr6:47512342ENST000003593142181_59106.33333333333333640.0DomainSH3 1%3B truncated


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Fusion Gene Sequence for SLC25A13-CD2AP


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000265631_ENST00000359314_TCGA-EI-6510-01A_SLC25A13_chr7_95813589_-_CD2AP_chr6_47512342_length(transcript)=5951nt_BP=1314nt
GGCCAGGAACGCACGCTGCCTGGCCGTATCGCCGCCCCCACCGCCGCCGCCGCCGGGACTAGAAGTGAGCCGCCCGGGTCCCAAACGCCA
GCCAGCCAGTCAGTGGGTCCCGCAGTCGCCCGCAACCGGGGCGAATCATGGCGGCCGCCAAGGTGGCTTTAACCAAGAGAGCAGATCCAG
CTGAGCTTAGAACAATATTTTTGAAGTATGCAAGCATTGAGAAAAACGGTGAATTTTTCATGTCCCCCAATGACTTTGTCACTCGATACT
TGAACATTTTTGGAGAAAGCCAGCCTAATCCAAAGACTGTGGAACTTTTAAGTGGAGTGGTGGATCAGACCAAAGATGGATTAATATCTT
TTCAAGAATTTGTTGCCTTTGAATCTGTCCTGTGTGCCCCTGATGCTTTGTTTATGGTAGCCTTTCAGCTGTTTGACAAAGCTGGCAAAG
GAGAAGTAACTTTTGAGGATGTTAAGCAAGTTTTTGGACAGACCACAATTCATCAACATATTCCATTTAACTGGGATTCAGAATTTGTGC
AACTACATTTTGGAAAAGAAAGAAAAAGACACCTGACATATGCGGAATTTACTCAGTTTTTATTGGAAATACAACTGGAGCACGCAAAGC
AAGCCTTTGTGCAACGGGACAATGCTAGGACTGGGAGAGTCACAGCCATCGACTTCCGAGACATCATGGTCACCATCCGCCCCCATGTCT
TGACTCCTTTTGTAGAAGAATGTCTAGTAGCTGCTGCTGGAGGTACCACATCCCATCAAGTTAGTTTCTCCTATTTTAATGGATTTAATT
CGCTCCTTAACAACATGGAACTCATTAGAAAGATCTATAGCACTCTGGCTGGCACCAGGAAAGATGTTGAAGTGACTAAGGAGGAGTTTG
TTCTGGCAGCTCAGAAATTTGGTCAGGTTACACCCATGGAAGTTGACATCTTGTTTCAGTTAGCAGATTTATATGAGCCAAGGGGACGTA
TGACCTTAGCAGACATTGAACGGATTGCTCCTCTGGAAGAGGGAACTCTGCCCTTTAACTTGGCTGAGGCCCAGAGGCAGAAGGCCTCAG
GTGATTCAGCTCGACCAGTTCTTCTACAAGTTGCAGAGTCGGCCTACAGGTTTGGTCTGGGTTCTGTTGCTGGAGCTGTTGGAGCCACTG
CTGTGTATCCTATCGATCTTGTAAAAACTCGAATGCAGAACCAACGATCAACTGGCTCTTTTGTGGGAGAACTCATGTATAAAAACAGCT
TTGACTGTTTTAAGAAAGTGCTACGCTATGAAGGCTTCTTTGGACTGTATAGAGAGACCAAGAAGCGTCAGTGTAAAGTTCTTTTTGAGT
ACATTCCACAAAATGAGGATGAACTGGAGCTGAAAGTGGGAGATATTATTGATATTAATGAAGAGGTAGAAGAAGGCTGGTGGAGTGGAA
CCCTGAATAACAAGTTGGGACTGTTTCCCTCAAATTTTGTGAAAGAATTAGAGGTAACAGATGATGGTGAAACTCATGAAGCCCAGGACG
ATTCAGAAACTGTTTTGGCTGGGCCTACTTCACCTATACCTTCTCTGGGAAATGTGAGTGAAACTGCATCTGGATCAGTTACACAGCCAA
AGAAAATTCGAGGAATTGGATTTGGAGACATTTTTAAAGAAGGCTCTGTGAAACTTCGGACAAGAACATCCAGTAGTGAAACAGAAGAGA
AAAAACCAGAAAAGCCCTTAATCCTACAGTCACTGGGACCCAAAACTCAGAGTGTGGAGATAACAAAAACAGATACCGAAGGTAAAATTA
AAGCTAAAGAATATTGTAGAACATTATTTGCCTATGAAGGTACTAATGAAGATGAACTTACTTTTAAAGAGGGGGAGATAATCCATTTGA
TAAGTAAGGAGACTGGAGAAGCTGGCTGGTGGAGGGGCGAACTTAATGGTAAAGAAGGAGTATTTCCAGACAATTTTGCTGTCCAGATAA
ATGAACTTGATAAAGACTTTCCAAAACCAAAGAAACCACCACCTCCTGCTAAGGCTCCAGCTCCAAAGCCTGAACTGATAGCTGCAGAGA
AGAAATATTTTTCTTTAAAGCCTGAAGAAAAGGATGAAAAATCAACACTGGAACAGAAACCTTCTAAACCAGCAGCTCCACAAGTCCCAC
CCAAGAAACCTACTCCACCTACCAAAGCCAGTAATTTACTGAGATCTTCTGGAACAGTGTACCCAAAGCGACCTGAAAAACCAGTTCCTC
CACCACCTCCTATAGCCAAGATTAATGGGGAAGTTTCTAGCATTTCATCAAAATTTGAAACTGAGCCAGTATCAAAACTAAAGCTAGATT
CTGAACAGCTGCCCCTTAGACCAAAATCAGTAGACTTTGATTCACTTACAGTAAGGACCTCCAAAGAAACAGATGTTGTAAATTTTGATG
ACATAGCTTCCTCAGAAAACTTGCTTCATCTCACTGCAAATAGACCAAAGATGCCTGGAAGAAGGTTGCCGGGCCGTTTCAATGGTGGAC
ATTCTCCAACTCACAGCCCCGAAAAAATCTTGAAGTTACCAAAAGAAGAAGACAGTGCCAACCTGAAGCCATCTGAATTAAAAAAAGATA
CATGCTACTCTCCAAAGCCATCTGTGTACCTTTCAACACCTTCCAGTGCTTCTAAAGCAAATACAACTGCTTTCCTGACTCCATTAGAAA
TCAAAGCTAAAGTGGAAACAGATGATGTGAAAAAAAATTCCCTGGATGAACTTAGAGCCCAGATTATTGAATTGTTGTGCATTGTAGAAG
CACTGAAAAAGGATCACGGGAAAGAACTGGAAAAACTGCGAAAAGATTTGGAAGAAGAGAAGACAATGAGAAGTAATCTAGAGATGGAAA
TAGAGAAGCTGAAAAAAGCTGTCCTGTCTTCTTGAGTGGTGTGGACCTGGTGTTCATAATGTTCCAGGGATTCAGAAGCAACGCTATGAA
CTTCAGCTGACTTGTTACTTAAAAATTGTGAATTCTGTTGTTGTGATAAATATGAGCAAATGAAGTGTAATATCTATAGAAAAGTAGAGT
GAGGGTGAATTTATATATATATTTTGTTTTGCCAATATGAAGAAAAAGAGGCCTTATTTCTTAACTGTGCTGGGATTGCAAACACTTTTT
AAAAAATTGTTTGCTTGAAAATACTACTGAATATAAATAAGAATGTGCACAGTAGTTTTTTTATTGAAACTTGTATTATTTTTAAAGAGA
TCTATACTATAAATATGGTGATATATTTACAAGTAATCTGTTAAGATATACTATTTGAGAGGGACAGATTAGCCTTTTAGTAACTATAGT
CACTACTTTTTCCATAATGCATAAGGGATATAAACTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATATATATAT
ATATATTTTTACTTTTATCCTCTTACCGAAGGTTACACTGTTGTGCCTGTTTGTCTGCAATGCTGTTTATATTTTGGGTGATGAAATAGG
AGTTTCCTAGCTATATAAACCAGATTACTCACCCATGCATATAGTAAGAACTAATGAATAATCAAAATAATTTCATCAACTTTTAGAATA
TTTTATGTTGCTTGCACTATAGGAGTCATAAAAGGAACTTAGTTAAAATATGTTGGATTGTTAAACATTTGGGGAAATATGAACTGTATT
TTAAATTTGTTAGGTCTGAAGAATCTAAAACTGTTAATTTAACCCTTAACTTGTGCCTAGAAACTACAGCACATATAAAATATGTAAACA
CCAGCCTGTTGCTGTACTTTTCTGCTTATTTTACAGCCTCAAATATTTCTCATTATCTTGTCACTTAGTTCTTCATGTTTCTCCTTCTGA
CTTTTAATAATGGTAATAGGAAAACAAAACCCAAAGCTTTTCAGAACTTCAGTGTGAGGTTTCCTATTTTGACAAGTTAACTTGTAAATA
CTCAGGTTTTACGATGTATAATTTACCTAATAGACCAAACTAACTCATGGAGATATTTTGAACTATTATTTAGGTACAAACTTTATAAAG
AATGTTAGTATGTCATAAAATATAACATTACAGCTTATTTAAAACCAAATATAGTTGAACATATTTAAAATACATTTTCACAGAATGGAT
GAATTAGTTGTTTCTTCAGAGTTACTTATGAACAGTTGAATGCTTTAAAATGTTCTGTCTGTAGGTAACATCTAAAACACAAGTGGGTTT
ATTTAAATTTTTAAAATTTGAAATTTTTTATTTGCAAAAAATTGTTTTATGCTTTATTATATCGCAAATGAGTGTCAGATTTTTGAGTAC
CAATGATCATGCTTCCATTTTTTTTAGTTTTAAACCACCAAACCAATATTTTTCCTTTAAATTTTAATCTTATAATATAGAAATCTTATG
TAAATGAAATTTTGTCATGTTTCAAATAAAGAGAACTGAAGTAGAAAATAGAAATGCCAGTAAACAACATAATGTTTAATTTACAACTTA
CATTAGGGGTTTGGGGGAATGCTAATTATATATTGAGAATATACATTAGAACTCTTCAAAATGGGCTCTTCTAATGAGGTCACTACTGAA
CAAAATTGTTCCCTCTTCTGTTAAATAGAATAGGTTTAAATGACTAGTCAAATGAATTATTTTCTTCTTGTTAAATAAATTAAATCTTAC
TTTCTTTTAATGACCAACCTTAGGTAAAACAAAAATATTGTAATCCTAGAAATTATCCTCCAGCTTTCTCACCTGAAAATCTATTGAAGT
GATCCCTGGTCATCCTAATAATGGGATGAGGGAAGTTTCCAGCAGATTTCAGGCTGTTCTTAAAGTTTTTGTTGGTCATTTTCTCAATAG
TACATGAAATCAAGATGCTTATGAGCATGGAAATGTATTTAAAGTTTTTGCTTGTGTCCTCCTCAGTCAGAATAGAAAAGTAACTGAAAT
ACTTTTACCTTTCTGTCCTTGATAAAATAGTAAAGAAAACCAAACAAACCCAGGCCTGATGGGAAAAATGATTCCTTTATTCTAGCAACT
TACTTTCTGTTGGTATGGGAAATGTTATTAATTTCTATTACTAAAGTTCATATCACAAAATGATATTTAATAATAACCTTGGGGTAAATC
ATGAATTTTTTTTCTACGTGTGAGTATAAAAGACAAAAGTTGAACAGCATGGAATCTCATTGCCAAATTATTAGTGAATGTATAGTTCAG
GTATTCTTTGAGACACACAGTATCATTAATTTCTGAATTGTATTTCAGTGTTATTTTTTGTTTGTGACCACTAAGCTTCTGTCTTAATAC
AAAGCTGTTACCTTCTACAGAATTTAAGTCTGAAGATGTAAAGAGAGAACAGGCCTTGTGTAACAGAAGATACTCTTTTTTATGCTCCTT
ACTGTGATCACAGAAAAATTAAAAATCCAAGTGCTCTCTAGATTTGTTGATAAACATTTTATGCTTGCATTTAAACTTGAAATGTATGAG
CAGAATGAGACAATCAGTTAAATCAGAAATGAGAAGTATTATAATGTAAAGGCCTTGTTTTGCTGTAGCAATAAAATGACCAAGTGCAAT
GACTTGATTTAATAAAATCATATTTTAAAAGTTGCTGCTATGAATATTTTTGGCTATAAAATTTTACCCTGACTTGCTTTCAATAACTGT
TACGTAATGCAGTTGATGTTGTAACCTAACATTCCAAAAAAAAAATTGAGAGGGGGAATCTCAAAATAGTATATACTTCACTAACTTGTT
TACAGGTGCTGTATTTAAAAGCATGCTTCTCTCTCAAAAAGAAAAATTAAAGGATTTTATTGCCAGTCGTGTCAGTCTTTATTGGTTATT
TTTTGTTAACTTTAGCATTTGTGTATTTCAGAGTATGATGAAAATTATATTACTTCAATTTCCAAATACAAGAATAAATAGTAAACCAAA

>In-frame_ENST00000265631_ENST00000359314_TCGA-EI-6510-01A_SLC25A13_chr7_95813589_-_CD2AP_chr6_47512342_length(amino acids)=925AA_start in transcript=137_stop in transcript=2914
MAAAKVALTKRADPAELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVELLSGVVDQTKDGLISFQEFVAFESVLCAPDA
LFMVAFQLFDKAGKGEVTFEDVKQVFGQTTIHQHIPFNWDSEFVQLHFGKERKRHLTYAEFTQFLLEIQLEHAKQAFVQRDNARTGRVTA
IDFRDIMVTIRPHVLTPFVEECLVAAAGGTTSHQVSFSYFNGFNSLLNNMELIRKIYSTLAGTRKDVEVTKEEFVLAAQKFGQVTPMEVD
ILFQLADLYEPRGRMTLADIERIAPLEEGTLPFNLAEAQRQKASGDSARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQR
STGSFVGELMYKNSFDCFKKVLRYEGFFGLYRETKKRQCKVLFEYIPQNEDELELKVGDIIDINEEVEEGWWSGTLNNKLGLFPSNFVKE
LEVTDDGETHEAQDDSETVLAGPTSPIPSLGNVSETASGSVTQPKKIRGIGFGDIFKEGSVKLRTRTSSSETEEKKPEKPLILQSLGPKT
QSVEITKTDTEGKIKAKEYCRTLFAYEGTNEDELTFKEGEIIHLISKETGEAGWWRGELNGKEGVFPDNFAVQINELDKDFPKPKKPPPP
AKAPAPKPELIAAEKKYFSLKPEEKDEKSTLEQKPSKPAAPQVPPKKPTPPTKASNLLRSSGTVYPKRPEKPVPPPPPIAKINGEVSSIS
SKFETEPVSKLKLDSEQLPLRPKSVDFDSLTVRTSKETDVVNFDDIASSENLLHLTANRPKMPGRRLPGRFNGGHSPTHSPEKILKLPKE
EDSANLKPSELKKDTCYSPKPSVYLSTPSSASKANTTAFLTPLEIKAKVETDDVKKNSLDELRAQIIELLCIVEALKKDHGKELEKLRKD

--------------------------------------------------------------
>In-frame_ENST00000416240_ENST00000359314_TCGA-EI-6510-01A_SLC25A13_chr7_95813589_-_CD2AP_chr6_47512342_length(transcript)=6008nt_BP=1371nt
AATGGGCGGGCAGCATCCACATGACCCGCGCCGGCGGGAGGGCGTGGGGAGGCAGGCCAGGAACGCACGCTGCCTGGCCGTATCGCCGCC
CCCACCGCCGCCGCCGCCGGGACTAGAAGTGAGCCGCCCGGGTCCCAAACGCCAGCCAGCCAGTCAGTGGGTCCCGCAGTCGCCCGCAAC
CGGGGCGAATCATGGCGGCCGCCAAGGTGGCTTTAACCAAGAGAGCAGATCCAGCTGAGCTTAGAACAATATTTTTGAAGTATGCAAGCA
TTGAGAAAAACGGTGAATTTTTCATGTCCCCCAATGACTTTGTCACTCGATACTTGAACATTTTTGGAGAAAGCCAGCCTAATCCAAAGA
CTGTGGAACTTTTAAGTGGAGTGGTGGATCAGACCAAAGATGGATTAATATCTTTTCAAGAATTTGTTGCCTTTGAATCTGTCCTGTGTG
CCCCTGATGCTTTGTTTATGGTAGCCTTTCAGCTGTTTGACAAAGCTGGCAAAGGAGAAGTAACTTTTGAGGATGTTAAGCAAGTTTTTG
GACAGACCACAATTCATCAACATATTCCATTTAACTGGGATTCAGAATTTGTGCAACTACATTTTGGAAAAGAAAGAAAAAGACACCTGA
CATATGCGGAATTTACTCAGTTTTTATTGGAAATACAACTGGAGCACGCAAAGCAAGCCTTTGTGCAACGGGACAATGCTAGGACTGGGA
GAGTCACAGCCATCGACTTCCGAGACATCATGGTCACCATCCGCCCCCATGTCTTGACTCCTTTTGTAGAAGAATGTCTAGTAGCTGCTG
CTGGAGGTACCACATCCCATCAAGTTAGTTTCTCCTATTTTAATGGATTTAATTCGCTCCTTAACAACATGGAACTCATTAGAAAGATCT
ATAGCACTCTGGCTGGCACCAGGAAAGATGTTGAAGTGACTAAGGAGGAGTTTGTTCTGGCAGCTCAGAAATTTGGTCAGGTTACACCCA
TGGAAGTTGACATCTTGTTTCAGTTAGCAGATTTATATGAGCCAAGGGGACGTATGACCTTAGCAGACATTGAACGGATTGCTCCTCTGG
AAGAGGGAACTCTGCCCTTTAACTTGGCTGAGGCCCAGAGGCAGCAGAAGGCCTCAGGTGATTCAGCTCGACCAGTTCTTCTACAAGTTG
CAGAGTCGGCCTACAGGTTTGGTCTGGGTTCTGTTGCTGGAGCTGTTGGAGCCACTGCTGTGTATCCTATCGATCTTGTAAAAACTCGAA
TGCAGAACCAACGATCAACTGGCTCTTTTGTGGGAGAACTCATGTATAAAAACAGCTTTGACTGTTTTAAGAAAGTGCTACGCTATGAAG
GCTTCTTTGGACTGTATAGAGAGACCAAGAAGCGTCAGTGTAAAGTTCTTTTTGAGTACATTCCACAAAATGAGGATGAACTGGAGCTGA
AAGTGGGAGATATTATTGATATTAATGAAGAGGTAGAAGAAGGCTGGTGGAGTGGAACCCTGAATAACAAGTTGGGACTGTTTCCCTCAA
ATTTTGTGAAAGAATTAGAGGTAACAGATGATGGTGAAACTCATGAAGCCCAGGACGATTCAGAAACTGTTTTGGCTGGGCCTACTTCAC
CTATACCTTCTCTGGGAAATGTGAGTGAAACTGCATCTGGATCAGTTACACAGCCAAAGAAAATTCGAGGAATTGGATTTGGAGACATTT
TTAAAGAAGGCTCTGTGAAACTTCGGACAAGAACATCCAGTAGTGAAACAGAAGAGAAAAAACCAGAAAAGCCCTTAATCCTACAGTCAC
TGGGACCCAAAACTCAGAGTGTGGAGATAACAAAAACAGATACCGAAGGTAAAATTAAAGCTAAAGAATATTGTAGAACATTATTTGCCT
ATGAAGGTACTAATGAAGATGAACTTACTTTTAAAGAGGGGGAGATAATCCATTTGATAAGTAAGGAGACTGGAGAAGCTGGCTGGTGGA
GGGGCGAACTTAATGGTAAAGAAGGAGTATTTCCAGACAATTTTGCTGTCCAGATAAATGAACTTGATAAAGACTTTCCAAAACCAAAGA
AACCACCACCTCCTGCTAAGGCTCCAGCTCCAAAGCCTGAACTGATAGCTGCAGAGAAGAAATATTTTTCTTTAAAGCCTGAAGAAAAGG
ATGAAAAATCAACACTGGAACAGAAACCTTCTAAACCAGCAGCTCCACAAGTCCCACCCAAGAAACCTACTCCACCTACCAAAGCCAGTA
ATTTACTGAGATCTTCTGGAACAGTGTACCCAAAGCGACCTGAAAAACCAGTTCCTCCACCACCTCCTATAGCCAAGATTAATGGGGAAG
TTTCTAGCATTTCATCAAAATTTGAAACTGAGCCAGTATCAAAACTAAAGCTAGATTCTGAACAGCTGCCCCTTAGACCAAAATCAGTAG
ACTTTGATTCACTTACAGTAAGGACCTCCAAAGAAACAGATGTTGTAAATTTTGATGACATAGCTTCCTCAGAAAACTTGCTTCATCTCA
CTGCAAATAGACCAAAGATGCCTGGAAGAAGGTTGCCGGGCCGTTTCAATGGTGGACATTCTCCAACTCACAGCCCCGAAAAAATCTTGA
AGTTACCAAAAGAAGAAGACAGTGCCAACCTGAAGCCATCTGAATTAAAAAAAGATACATGCTACTCTCCAAAGCCATCTGTGTACCTTT
CAACACCTTCCAGTGCTTCTAAAGCAAATACAACTGCTTTCCTGACTCCATTAGAAATCAAAGCTAAAGTGGAAACAGATGATGTGAAAA
AAAATTCCCTGGATGAACTTAGAGCCCAGATTATTGAATTGTTGTGCATTGTAGAAGCACTGAAAAAGGATCACGGGAAAGAACTGGAAA
AACTGCGAAAAGATTTGGAAGAAGAGAAGACAATGAGAAGTAATCTAGAGATGGAAATAGAGAAGCTGAAAAAAGCTGTCCTGTCTTCTT
GAGTGGTGTGGACCTGGTGTTCATAATGTTCCAGGGATTCAGAAGCAACGCTATGAACTTCAGCTGACTTGTTACTTAAAAATTGTGAAT
TCTGTTGTTGTGATAAATATGAGCAAATGAAGTGTAATATCTATAGAAAAGTAGAGTGAGGGTGAATTTATATATATATTTTGTTTTGCC
AATATGAAGAAAAAGAGGCCTTATTTCTTAACTGTGCTGGGATTGCAAACACTTTTTAAAAAATTGTTTGCTTGAAAATACTACTGAATA
TAAATAAGAATGTGCACAGTAGTTTTTTTATTGAAACTTGTATTATTTTTAAAGAGATCTATACTATAAATATGGTGATATATTTACAAG
TAATCTGTTAAGATATACTATTTGAGAGGGACAGATTAGCCTTTTAGTAACTATAGTCACTACTTTTTCCATAATGCATAAGGGATATAA
ACTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATATATATATATATATTTTTACTTTTATCCTCTTACCGAAGGT
TACACTGTTGTGCCTGTTTGTCTGCAATGCTGTTTATATTTTGGGTGATGAAATAGGAGTTTCCTAGCTATATAAACCAGATTACTCACC
CATGCATATAGTAAGAACTAATGAATAATCAAAATAATTTCATCAACTTTTAGAATATTTTATGTTGCTTGCACTATAGGAGTCATAAAA
GGAACTTAGTTAAAATATGTTGGATTGTTAAACATTTGGGGAAATATGAACTGTATTTTAAATTTGTTAGGTCTGAAGAATCTAAAACTG
TTAATTTAACCCTTAACTTGTGCCTAGAAACTACAGCACATATAAAATATGTAAACACCAGCCTGTTGCTGTACTTTTCTGCTTATTTTA
CAGCCTCAAATATTTCTCATTATCTTGTCACTTAGTTCTTCATGTTTCTCCTTCTGACTTTTAATAATGGTAATAGGAAAACAAAACCCA
AAGCTTTTCAGAACTTCAGTGTGAGGTTTCCTATTTTGACAAGTTAACTTGTAAATACTCAGGTTTTACGATGTATAATTTACCTAATAG
ACCAAACTAACTCATGGAGATATTTTGAACTATTATTTAGGTACAAACTTTATAAAGAATGTTAGTATGTCATAAAATATAACATTACAG
CTTATTTAAAACCAAATATAGTTGAACATATTTAAAATACATTTTCACAGAATGGATGAATTAGTTGTTTCTTCAGAGTTACTTATGAAC
AGTTGAATGCTTTAAAATGTTCTGTCTGTAGGTAACATCTAAAACACAAGTGGGTTTATTTAAATTTTTAAAATTTGAAATTTTTTATTT
GCAAAAAATTGTTTTATGCTTTATTATATCGCAAATGAGTGTCAGATTTTTGAGTACCAATGATCATGCTTCCATTTTTTTTAGTTTTAA
ACCACCAAACCAATATTTTTCCTTTAAATTTTAATCTTATAATATAGAAATCTTATGTAAATGAAATTTTGTCATGTTTCAAATAAAGAG
AACTGAAGTAGAAAATAGAAATGCCAGTAAACAACATAATGTTTAATTTACAACTTACATTAGGGGTTTGGGGGAATGCTAATTATATAT
TGAGAATATACATTAGAACTCTTCAAAATGGGCTCTTCTAATGAGGTCACTACTGAACAAAATTGTTCCCTCTTCTGTTAAATAGAATAG
GTTTAAATGACTAGTCAAATGAATTATTTTCTTCTTGTTAAATAAATTAAATCTTACTTTCTTTTAATGACCAACCTTAGGTAAAACAAA
AATATTGTAATCCTAGAAATTATCCTCCAGCTTTCTCACCTGAAAATCTATTGAAGTGATCCCTGGTCATCCTAATAATGGGATGAGGGA
AGTTTCCAGCAGATTTCAGGCTGTTCTTAAAGTTTTTGTTGGTCATTTTCTCAATAGTACATGAAATCAAGATGCTTATGAGCATGGAAA
TGTATTTAAAGTTTTTGCTTGTGTCCTCCTCAGTCAGAATAGAAAAGTAACTGAAATACTTTTACCTTTCTGTCCTTGATAAAATAGTAA
AGAAAACCAAACAAACCCAGGCCTGATGGGAAAAATGATTCCTTTATTCTAGCAACTTACTTTCTGTTGGTATGGGAAATGTTATTAATT
TCTATTACTAAAGTTCATATCACAAAATGATATTTAATAATAACCTTGGGGTAAATCATGAATTTTTTTTCTACGTGTGAGTATAAAAGA
CAAAAGTTGAACAGCATGGAATCTCATTGCCAAATTATTAGTGAATGTATAGTTCAGGTATTCTTTGAGACACACAGTATCATTAATTTC
TGAATTGTATTTCAGTGTTATTTTTTGTTTGTGACCACTAAGCTTCTGTCTTAATACAAAGCTGTTACCTTCTACAGAATTTAAGTCTGA
AGATGTAAAGAGAGAACAGGCCTTGTGTAACAGAAGATACTCTTTTTTATGCTCCTTACTGTGATCACAGAAAAATTAAAAATCCAAGTG
CTCTCTAGATTTGTTGATAAACATTTTATGCTTGCATTTAAACTTGAAATGTATGAGCAGAATGAGACAATCAGTTAAATCAGAAATGAG
AAGTATTATAATGTAAAGGCCTTGTTTTGCTGTAGCAATAAAATGACCAAGTGCAATGACTTGATTTAATAAAATCATATTTTAAAAGTT
GCTGCTATGAATATTTTTGGCTATAAAATTTTACCCTGACTTGCTTTCAATAACTGTTACGTAATGCAGTTGATGTTGTAACCTAACATT
CCAAAAAAAAAATTGAGAGGGGGAATCTCAAAATAGTATATACTTCACTAACTTGTTTACAGGTGCTGTATTTAAAAGCATGCTTCTCTC
TCAAAAAGAAAAATTAAAGGATTTTATTGCCAGTCGTGTCAGTCTTTATTGGTTATTTTTTGTTAACTTTAGCATTTGTGTATTTCAGAG

>In-frame_ENST00000416240_ENST00000359314_TCGA-EI-6510-01A_SLC25A13_chr7_95813589_-_CD2AP_chr6_47512342_length(amino acids)=926AA_start in transcript=191_stop in transcript=2971
MAAAKVALTKRADPAELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVELLSGVVDQTKDGLISFQEFVAFESVLCAPDA
LFMVAFQLFDKAGKGEVTFEDVKQVFGQTTIHQHIPFNWDSEFVQLHFGKERKRHLTYAEFTQFLLEIQLEHAKQAFVQRDNARTGRVTA
IDFRDIMVTIRPHVLTPFVEECLVAAAGGTTSHQVSFSYFNGFNSLLNNMELIRKIYSTLAGTRKDVEVTKEEFVLAAQKFGQVTPMEVD
ILFQLADLYEPRGRMTLADIERIAPLEEGTLPFNLAEAQRQQKASGDSARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQ
RSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRETKKRQCKVLFEYIPQNEDELELKVGDIIDINEEVEEGWWSGTLNNKLGLFPSNFVK
ELEVTDDGETHEAQDDSETVLAGPTSPIPSLGNVSETASGSVTQPKKIRGIGFGDIFKEGSVKLRTRTSSSETEEKKPEKPLILQSLGPK
TQSVEITKTDTEGKIKAKEYCRTLFAYEGTNEDELTFKEGEIIHLISKETGEAGWWRGELNGKEGVFPDNFAVQINELDKDFPKPKKPPP
PAKAPAPKPELIAAEKKYFSLKPEEKDEKSTLEQKPSKPAAPQVPPKKPTPPTKASNLLRSSGTVYPKRPEKPVPPPPPIAKINGEVSSI
SSKFETEPVSKLKLDSEQLPLRPKSVDFDSLTVRTSKETDVVNFDDIASSENLLHLTANRPKMPGRRLPGRFNGGHSPTHSPEKILKLPK
EEDSANLKPSELKKDTCYSPKPSVYLSTPSSASKANTTAFLTPLEIKAKVETDDVKKNSLDELRAQIIELLCIVEALKKDHGKELEKLRK

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SLC25A13-CD2AP


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneCD2APchr7:95813589chr6:47512342ENST000003593142181_175106.33333333333333640.0ANLN and localization to the midbody


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SLC25A13-CD2AP


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SLC25A13-CD2AP


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneSLC25A13C1853942CITRULLINEMIA, TYPE II, NEONATAL-ONSET3CTD_human;GENOMICS_ENGLAND;UNIPROT
HgeneSLC25A13C1863844Adult-onset citrullinemia type 23CTD_human;GENOMICS_ENGLAND
HgeneSLC25A13C0023893Liver Cirrhosis, Experimental1CTD_human
TgeneCD2APC0002395Alzheimer's Disease3CTD_human
TgeneCD2APC0011265Presenile dementia3CTD_human
TgeneCD2APC0276496Familial Alzheimer Disease (FAD)3CTD_human
TgeneCD2APC0494463Alzheimer Disease, Late Onset3CTD_human
TgeneCD2APC0546126Acute Confusional Senile Dementia3CTD_human
TgeneCD2APC0750900Alzheimer's Disease, Focal Onset3CTD_human
TgeneCD2APC0750901Alzheimer Disease, Early Onset3CTD_human
TgeneCD2APC1842982FOCAL SEGMENTAL GLOMERULOSCLEROSIS 3, SUSCEPTIBILITY TO2GENOMICS_ENGLAND
TgeneCD2APC1868672NEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE1ORPHANET