|
||||||
|
 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:SLC35A1-FUS (FusionGDB2 ID:82352) |
Fusion Gene Summary for SLC35A1-FUS |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SLC35A1-FUS | Fusion gene ID: 82352 | Hgene | Tgene | Gene symbol | SLC35A1 | FUS | Gene ID | 10559 | 2521 |
| Gene name | solute carrier family 35 member A1 | FUS RNA binding protein | |
| Synonyms | CDG2F|CMPST|CST|hCST | ALS6|ETM4|FUS1|HNRNPP2|POMP75|TLS | |
| Cytomap | 6q15 | 16p11.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | CMP-sialic acid transporterCMP-SA-TrCMP-Sia-Trmutated CMP-sialic acid transporter A1solute carrier family 35 (CMP-sialic acid transporter), member 1solute carrier family 35 (CMP-sialic acid transporter), member A1solute carrier family 35 (UDP-galact | RNA-binding protein FUS75 kDa DNA-pairing proteinfus-like proteinfused in sarcomafusion gene in myxoid liposarcomaheterogeneous nuclear ribonucleoprotein P2oncogene FUSoncogene TLStranslocated in liposarcoma protein | |
| Modification date | 20200313 | 20200329 | |
| UniProtAcc | . | P35637 | |
| Ensembl transtripts involved in fusion gene | ENST00000464978, ENST00000369556, ENST00000544441, ENST00000369552, ENST00000369557, | ENST00000254108, ENST00000380244, ENST00000568685, ENST00000474990, | |
| Fusion gene scores | * DoF score | 4 X 3 X 3=36 | 20 X 13 X 10=2600 |
| # samples | 3 | 22 | |
| ** MAII score | log2(3/36*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(22/2600*10)=-3.56293619439116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SLC35A1 [Title/Abstract] AND FUS [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | SLC35A1(88182737)-FUS(31199646), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | FUS | GO:0006355 | regulation of transcription, DNA-templated | 26124092 |
| Tgene | FUS | GO:0006357 | regulation of transcription by RNA polymerase II | 25453086 |
| Tgene | FUS | GO:0008380 | RNA splicing | 26124092 |
| Tgene | FUS | GO:0043484 | regulation of RNA splicing | 25453086|27731383 |
| Tgene | FUS | GO:0048255 | mRNA stabilization | 27378374 |
| Tgene | FUS | GO:0051260 | protein homooligomerization | 25453086 |
| Tgene | FUS | GO:1905168 | positive regulation of double-strand break repair via homologous recombination | 10567410 |
| Fusion gene breakpoints across SLC35A1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene breakpoints across FUS (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | STAD | TCGA-CD-8527-01A | SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199646 | + |
Top |
Fusion Gene ORF analysis for SLC35A1-FUS |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000464978 | ENST00000254108 | SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199646 | + |
| intron-3CDS | ENST00000464978 | ENST00000380244 | SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199646 | + |
| intron-3CDS | ENST00000464978 | ENST00000568685 | SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199646 | + |
| intron-3UTR | ENST00000464978 | ENST00000474990 | SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199646 | + |
| In-frame | ENST00000369556 | ENST00000254108 | SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199646 | + |
| In-frame | ENST00000369556 | ENST00000380244 | SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199646 | + |
| In-frame | ENST00000369556 | ENST00000568685 | SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199646 | + |
| 5CDS-3UTR | ENST00000369556 | ENST00000474990 | SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199646 | + |
| 5UTR-3CDS | ENST00000544441 | ENST00000254108 | SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199646 | + |
| 5UTR-3CDS | ENST00000544441 | ENST00000380244 | SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199646 | + |
| 5UTR-3CDS | ENST00000544441 | ENST00000568685 | SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199646 | + |
| 5UTR-3UTR | ENST00000544441 | ENST00000474990 | SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199646 | + |
| In-frame | ENST00000369552 | ENST00000254108 | SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199646 | + |
| In-frame | ENST00000369552 | ENST00000380244 | SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199646 | + |
| In-frame | ENST00000369552 | ENST00000568685 | SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199646 | + |
| 5CDS-3UTR | ENST00000369552 | ENST00000474990 | SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199646 | + |
| In-frame | ENST00000369557 | ENST00000254108 | SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199646 | + |
| In-frame | ENST00000369557 | ENST00000380244 | SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199646 | + |
| In-frame | ENST00000369557 | ENST00000568685 | SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199646 | + |
| 5CDS-3UTR | ENST00000369557 | ENST00000474990 | SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199646 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000369556 | SLC35A1 | chr6 | 88182737 | + | ENST00000254108 | FUS | chr16 | 31199646 | + | 1245 | 95 | 22 | 876 | 284 |
| ENST00000369556 | SLC35A1 | chr6 | 88182737 | + | ENST00000380244 | FUS | chr16 | 31199646 | + | 1041 | 95 | 22 | 876 | 284 |
| ENST00000369556 | SLC35A1 | chr6 | 88182737 | + | ENST00000568685 | FUS | chr16 | 31199646 | + | 1017 | 95 | 22 | 879 | 285 |
| ENST00000369552 | SLC35A1 | chr6 | 88182737 | + | ENST00000254108 | FUS | chr16 | 31199646 | + | 1193 | 43 | 27 | 824 | 265 |
| ENST00000369552 | SLC35A1 | chr6 | 88182737 | + | ENST00000380244 | FUS | chr16 | 31199646 | + | 989 | 43 | 27 | 824 | 265 |
| ENST00000369552 | SLC35A1 | chr6 | 88182737 | + | ENST00000568685 | FUS | chr16 | 31199646 | + | 965 | 43 | 27 | 827 | 266 |
| ENST00000369557 | SLC35A1 | chr6 | 88182737 | + | ENST00000254108 | FUS | chr16 | 31199646 | + | 1166 | 16 | 0 | 797 | 265 |
| ENST00000369557 | SLC35A1 | chr6 | 88182737 | + | ENST00000380244 | FUS | chr16 | 31199646 | + | 962 | 16 | 0 | 797 | 265 |
| ENST00000369557 | SLC35A1 | chr6 | 88182737 | + | ENST00000568685 | FUS | chr16 | 31199646 | + | 938 | 16 | 0 | 800 | 266 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000369556 | ENST00000254108 | SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199646 | + | 0.004675024 | 0.99532497 |
| ENST00000369556 | ENST00000380244 | SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199646 | + | 0.004958341 | 0.99504167 |
| ENST00000369556 | ENST00000568685 | SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199646 | + | 0.003332728 | 0.9966673 |
| ENST00000369552 | ENST00000254108 | SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199646 | + | 0.006158842 | 0.9938412 |
| ENST00000369552 | ENST00000380244 | SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199646 | + | 0.006804985 | 0.99319506 |
| ENST00000369552 | ENST00000568685 | SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199646 | + | 0.00458449 | 0.99541545 |
| ENST00000369557 | ENST00000254108 | SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199646 | + | 0.00719418 | 0.9928059 |
| ENST00000369557 | ENST00000380244 | SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199646 | + | 0.008175451 | 0.99182457 |
| ENST00000369557 | ENST00000568685 | SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199646 | + | 0.005198475 | 0.9948015 |
Top |
Fusion Genomic Features for SLC35A1-FUS |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199645 | + | 1.64E-05 | 0.99998367 |
| SLC35A1 | chr6 | 88182737 | + | FUS | chr16 | 31199645 | + | 1.64E-05 | 0.99998367 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
Top |
Fusion Protein Features for SLC35A1-FUS |
| Go to FGviewer for the breakpoints of chr6:88182737-chr16:31199646 - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. |
 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | FUS |
| FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes. | FUNCTION: DNA/RNA-binding protein that plays a role in various cellular processes such as transcription regulation, RNA splicing, RNA transport, DNA repair and damage response (PubMed:27731383). Binds to nascent pre-mRNAs and acts as a molecular mediator between RNA polymerase II and U1 small nuclear ribonucleoprotein thereby coupling transcription and splicing (PubMed:26124092). Binds also its own pre-mRNA and autoregulates its expression; this autoregulation mechanism is mediated by non-sense-mediated decay (PubMed:24204307). Plays a role in DNA repair mechanisms by promoting D-loop formation and homologous recombination during DNA double-strand break repair (PubMed:10567410). In neuronal cells, plays crucial roles in dendritic spine formation and stability, RNA transport, mRNA stability and synaptic homeostasis (By similarity). {ECO:0000250|UniProtKB:P56959, ECO:0000269|PubMed:10567410, ECO:0000269|PubMed:24204307, ECO:0000269|PubMed:26124092, ECO:0000269|PubMed:27731383}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | FUS | chr6:88182737 | chr16:31199646 | ENST00000254108 | 6 | 15 | 371_526 | 266.3333333333333 | 527.0 | Compositional bias | Note=Arg/Gly-rich | |
| Tgene | FUS | chr6:88182737 | chr16:31199646 | ENST00000380244 | 6 | 15 | 371_526 | 265.3333333333333 | 526.0 | Compositional bias | Note=Arg/Gly-rich | |
| Tgene | FUS | chr6:88182737 | chr16:31199646 | ENST00000254108 | 6 | 15 | 285_371 | 266.3333333333333 | 527.0 | Domain | RRM | |
| Tgene | FUS | chr6:88182737 | chr16:31199646 | ENST00000380244 | 6 | 15 | 285_371 | 265.3333333333333 | 526.0 | Domain | RRM | |
| Tgene | FUS | chr6:88182737 | chr16:31199646 | ENST00000254108 | 6 | 15 | 422_453 | 266.3333333333333 | 527.0 | Zinc finger | RanBP2-type | |
| Tgene | FUS | chr6:88182737 | chr16:31199646 | ENST00000380244 | 6 | 15 | 422_453 | 265.3333333333333 | 526.0 | Zinc finger | RanBP2-type |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369552 | + | 1 | 8 | 101_102 | 5.333333333333333 | 338.0 | Region | CMP-sialic acid binding |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369552 | + | 1 | 8 | 117_124 | 5.333333333333333 | 338.0 | Region | CMP-sialic acid binding |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369552 | + | 1 | 8 | 210_214 | 5.333333333333333 | 338.0 | Region | CMP-sialic acid binding |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369552 | + | 1 | 8 | 316_337 | 5.333333333333333 | 338.0 | Region | Intrinsically disordered |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369556 | + | 1 | 7 | 101_102 | 5.333333333333333 | 279.0 | Region | CMP-sialic acid binding |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369556 | + | 1 | 7 | 117_124 | 5.333333333333333 | 279.0 | Region | CMP-sialic acid binding |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369556 | + | 1 | 7 | 210_214 | 5.333333333333333 | 279.0 | Region | CMP-sialic acid binding |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369556 | + | 1 | 7 | 316_337 | 5.333333333333333 | 279.0 | Region | Intrinsically disordered |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369552 | + | 1 | 8 | 109_114 | 5.333333333333333 | 338.0 | Topological domain | Lumenal |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369552 | + | 1 | 8 | 136_141 | 5.333333333333333 | 338.0 | Topological domain | Cytoplasmic |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369552 | + | 1 | 8 | 161_175 | 5.333333333333333 | 338.0 | Topological domain | Lumenal |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369552 | + | 1 | 8 | 197_209 | 5.333333333333333 | 338.0 | Topological domain | Cytoplasmic |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369552 | + | 1 | 8 | 1_9 | 5.333333333333333 | 338.0 | Topological domain | Cytoplasmic |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369552 | + | 1 | 8 | 229_243 | 5.333333333333333 | 338.0 | Topological domain | Lumenal |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369552 | + | 1 | 8 | 263_269 | 5.333333333333333 | 338.0 | Topological domain | Cytoplasmic |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369552 | + | 1 | 8 | 289_296 | 5.333333333333333 | 338.0 | Topological domain | Lumenal |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369552 | + | 1 | 8 | 31_45 | 5.333333333333333 | 338.0 | Topological domain | Lumenal |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369552 | + | 1 | 8 | 65_87 | 5.333333333333333 | 338.0 | Topological domain | Cytoplasmic |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369556 | + | 1 | 7 | 109_114 | 5.333333333333333 | 279.0 | Topological domain | Lumenal |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369556 | + | 1 | 7 | 136_141 | 5.333333333333333 | 279.0 | Topological domain | Cytoplasmic |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369556 | + | 1 | 7 | 161_175 | 5.333333333333333 | 279.0 | Topological domain | Lumenal |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369556 | + | 1 | 7 | 197_209 | 5.333333333333333 | 279.0 | Topological domain | Cytoplasmic |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369556 | + | 1 | 7 | 1_9 | 5.333333333333333 | 279.0 | Topological domain | Cytoplasmic |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369556 | + | 1 | 7 | 229_243 | 5.333333333333333 | 279.0 | Topological domain | Lumenal |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369556 | + | 1 | 7 | 263_269 | 5.333333333333333 | 279.0 | Topological domain | Cytoplasmic |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369556 | + | 1 | 7 | 289_296 | 5.333333333333333 | 279.0 | Topological domain | Lumenal |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369556 | + | 1 | 7 | 31_45 | 5.333333333333333 | 279.0 | Topological domain | Lumenal |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369556 | + | 1 | 7 | 65_87 | 5.333333333333333 | 279.0 | Topological domain | Cytoplasmic |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369552 | + | 1 | 8 | 10_30 | 5.333333333333333 | 338.0 | Transmembrane | Helical |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369552 | + | 1 | 8 | 115_135 | 5.333333333333333 | 338.0 | Transmembrane | Helical |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369552 | + | 1 | 8 | 142_160 | 5.333333333333333 | 338.0 | Transmembrane | Helical |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369552 | + | 1 | 8 | 176_196 | 5.333333333333333 | 338.0 | Transmembrane | Helical |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369552 | + | 1 | 8 | 210_228 | 5.333333333333333 | 338.0 | Transmembrane | Helical |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369552 | + | 1 | 8 | 244_262 | 5.333333333333333 | 338.0 | Transmembrane | Helical |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369552 | + | 1 | 8 | 270_288 | 5.333333333333333 | 338.0 | Transmembrane | Helical |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369552 | + | 1 | 8 | 297_315 | 5.333333333333333 | 338.0 | Transmembrane | Helical |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369552 | + | 1 | 8 | 46_64 | 5.333333333333333 | 338.0 | Transmembrane | Helical |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369552 | + | 1 | 8 | 88_108 | 5.333333333333333 | 338.0 | Transmembrane | Helical |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369556 | + | 1 | 7 | 10_30 | 5.333333333333333 | 279.0 | Transmembrane | Helical |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369556 | + | 1 | 7 | 115_135 | 5.333333333333333 | 279.0 | Transmembrane | Helical |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369556 | + | 1 | 7 | 142_160 | 5.333333333333333 | 279.0 | Transmembrane | Helical |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369556 | + | 1 | 7 | 176_196 | 5.333333333333333 | 279.0 | Transmembrane | Helical |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369556 | + | 1 | 7 | 210_228 | 5.333333333333333 | 279.0 | Transmembrane | Helical |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369556 | + | 1 | 7 | 244_262 | 5.333333333333333 | 279.0 | Transmembrane | Helical |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369556 | + | 1 | 7 | 270_288 | 5.333333333333333 | 279.0 | Transmembrane | Helical |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369556 | + | 1 | 7 | 297_315 | 5.333333333333333 | 279.0 | Transmembrane | Helical |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369556 | + | 1 | 7 | 46_64 | 5.333333333333333 | 279.0 | Transmembrane | Helical |
| Hgene | SLC35A1 | chr6:88182737 | chr16:31199646 | ENST00000369556 | + | 1 | 7 | 88_108 | 5.333333333333333 | 279.0 | Transmembrane | Helical |
| Tgene | FUS | chr6:88182737 | chr16:31199646 | ENST00000254108 | 6 | 15 | 166_267 | 266.3333333333333 | 527.0 | Compositional bias | Note=Gly-rich | |
| Tgene | FUS | chr6:88182737 | chr16:31199646 | ENST00000254108 | 6 | 15 | 1_165 | 266.3333333333333 | 527.0 | Compositional bias | Note=Gln/Gly/Ser/Tyr-rich | |
| Tgene | FUS | chr6:88182737 | chr16:31199646 | ENST00000380244 | 6 | 15 | 166_267 | 265.3333333333333 | 526.0 | Compositional bias | Note=Gly-rich | |
| Tgene | FUS | chr6:88182737 | chr16:31199646 | ENST00000380244 | 6 | 15 | 1_165 | 265.3333333333333 | 526.0 | Compositional bias | Note=Gln/Gly/Ser/Tyr-rich |
Top |
Fusion Gene Sequence for SLC35A1-FUS |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >In-frame_ENST00000369556_ENST00000254108_TCGA-CD-8527-01A_SLC35A1_chr6_88182737_+_FUS_chr16_31199646_length(transcript)=1245nt_BP=95nt ACAAGGGGCGGTCCCCGGTGTCCTGCGCGGGGGCGCGGAGGGGGCGGGCGTCAGTTCCGCGGGGGGCTGTCGGGGAACCATGGCTGCCCC GAGAGGCCCTCGGGACCAAGGATCACGTCATGACTCCGAACAGGATAATTCAGACAACAACACCATCTTTGTGCAAGGCCTGGGTGAGAA TGTTACAATTGAGTCTGTGGCTGATTACTTCAAGCAGATTGGTATTATTAAGACAAACAAGAAAACGGGACAGCCCATGATTAATTTGTA CACAGACAGGGAAACTGGCAAGCTGAAGGGAGAGGCAACGGTCTCTTTTGATGACCCACCTTCAGCTAAAGCAGCTATTGACTGGTTTGA TGGTAAAGAATTCTCCGGAAATCCTATCAAGGTCTCATTTGCTACTCGCCGGGCAGACTTTAATCGGGGTGGTGGCAATGGTCGTGGAGG CCGAGGGCGAGGAGGACCCATGGGCCGTGGAGGCTATGGAGGTGGTGGCAGTGGTGGTGGTGGCCGAGGAGGATTTCCCAGTGGAGGTGG TGGCGGTGGAGGACAGCAGCGAGCTGGTGACTGGAAGTGTCCTAATCCCACCTGTGAGAATATGAACTTCTCTTGGAGGAATGAATGCAA CCAGTGTAAGGCCCCTAAACCAGATGGCCCAGGAGGGGGACCAGGTGGCTCTCACATGGGGGGTAACTACGGGGATGATCGTCGTGGTGG CAGAGGAGGCTATGATCGAGGCGGCTACCGGGGCCGCGGCGGGGACCGTGGAGGCTTCCGAGGGGGCCGGGGTGGTGGGGACAGAGGTGG CTTTGGCCCTGGCAAGATGGATTCCAGGGGTGAGCACAGACAGGATCGCAGGGAGAGGCCGTATTAATTAGCCTGGCTCCCCAGGTTCTG GAACAGCTTTTTGTCCTGTACCCAGTGTTACCCTCGTTATTTTGTAACCTTCCAATTCCTGATCACCCAAGGGTTTTTTTGTGTCGGACT ATGTAATTGTAACTATACCTCTGGTTCCCATTAAAAGTGACCATTTTAGTTAAATTTTGTTCCTCTTCCCCCTTTTCACTTTCCTGGAAG ATCGATGTCCCGATCAGGAAGGTAGAGAGTTTTCCTGTTCAGATTACCCTGCCCAGCAGGAACTGGAATACAGTGTTCGGGGAGAAGGCC >In-frame_ENST00000369556_ENST00000254108_TCGA-CD-8527-01A_SLC35A1_chr6_88182737_+_FUS_chr16_31199646_length(amino acids)=284AA_start in transcript=22_stop in transcript=876 MRGGAEGAGVSSAGGCRGTMAAPRGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGK LKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQR AGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMD -------------------------------------------------------------- >In-frame_ENST00000369556_ENST00000380244_TCGA-CD-8527-01A_SLC35A1_chr6_88182737_+_FUS_chr16_31199646_length(transcript)=1041nt_BP=95nt ACAAGGGGCGGTCCCCGGTGTCCTGCGCGGGGGCGCGGAGGGGGCGGGCGTCAGTTCCGCGGGGGGCTGTCGGGGAACCATGGCTGCCCC GAGAGGCCCTCGGGACCAAGGATCACGTCATGACTCCGAACAGGATAATTCAGACAACAACACCATCTTTGTGCAAGGCCTGGGTGAGAA TGTTACAATTGAGTCTGTGGCTGATTACTTCAAGCAGATTGGTATTATTAAGACAAACAAGAAAACGGGACAGCCCATGATTAATTTGTA CACAGACAGGGAAACTGGCAAGCTGAAGGGAGAGGCAACGGTCTCTTTTGATGACCCACCTTCAGCTAAAGCAGCTATTGACTGGTTTGA TGGTAAAGAATTCTCCGGAAATCCTATCAAGGTCTCATTTGCTACTCGCCGGGCAGACTTTAATCGGGGTGGTGGCAATGGTCGTGGAGG CCGAGGGCGAGGAGGACCCATGGGCCGTGGAGGCTATGGAGGTGGTGGCAGTGGTGGTGGTGGCCGAGGAGGATTTCCCAGTGGAGGTGG TGGCGGTGGAGGACAGCAGCGAGCTGGTGACTGGAAGTGTCCTAATCCCACCTGTGAGAATATGAACTTCTCTTGGAGGAATGAATGCAA CCAGTGTAAGGCCCCTAAACCAGATGGCCCAGGAGGGGGACCAGGTGGCTCTCACATGGGGGGTAACTACGGGGATGATCGTCGTGGTGG CAGAGGAGGCTATGATCGAGGCGGCTACCGGGGCCGCGGCGGGGACCGTGGAGGCTTCCGAGGGGGCCGGGGTGGTGGGGACAGAGGTGG CTTTGGCCCTGGCAAGATGGATTCCAGGGGTGAGCACAGACAGGATCGCAGGGAGAGGCCGTATTAATTAGCCTGGCTCCCCAGGTTCTG GAACAGCTTTTTGTCCTGTACCCAGTGTTACCCTCGTTATTTTGTAACCTTCCAATTCCTGATCACCCAAGGGTTTTTTTGTGTCGGACT >In-frame_ENST00000369556_ENST00000380244_TCGA-CD-8527-01A_SLC35A1_chr6_88182737_+_FUS_chr16_31199646_length(amino acids)=284AA_start in transcript=22_stop in transcript=876 MRGGAEGAGVSSAGGCRGTMAAPRGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGK LKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQR AGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMD -------------------------------------------------------------- >In-frame_ENST00000369556_ENST00000568685_TCGA-CD-8527-01A_SLC35A1_chr6_88182737_+_FUS_chr16_31199646_length(transcript)=1017nt_BP=95nt ACAAGGGGCGGTCCCCGGTGTCCTGCGCGGGGGCGCGGAGGGGGCGGGCGTCAGTTCCGCGGGGGGCTGTCGGGGAACCATGGCTGCCCC GAGAGGCCCTCGGGACCAAGGATCACGTCATGACTCCGCAGAACAGGATAATTCAGACAACAACACCATCTTTGTGCAAGGCCTGGGTGA GAATGTTACAATTGAGTCTGTGGCTGATTACTTCAAGCAGATTGGTATTATTAAGACAAACAAGAAAACGGGACAGCCCATGATTAATTT GTACACAGACAGGGAAACTGGCAAGCTGAAGGGAGAGGCAACGGTCTCTTTTGATGACCCACCTTCAGCTAAAGCAGCTATTGACTGGTT TGATGGTAAAGAATTCTCCGGAAATCCTATCAAGGTCTCATTTGCTACTCGCCGGGCAGACTTTAATCGGGGTGGTGGCAATGGTCGTGG AGGCCGAGGGCGAGGAGGACCCATGGGCCGTGGAGGCTATGGAGGTGGTGGCAGTGGTGGTGGTGGCCGAGGAGGATTTCCCAGTGGAGG TGGTGGCGGTGGAGGACAGCAGCGAGCTGGTGACTGGAAGTGTCCTAATCCCACCTGTGAGAATATGAACTTCTCTTGGAGGAATGAATG CAACCAGTGTAAGGCCCCTAAACCAGATGGCCCAGGAGGGGGACCAGGTGGCTCTCACATGGGGGGTAACTACGGGGATGATCGTCGTGG TGGCAGAGGAGGCTATGATCGAGGCGGCTACCGGGGCCGCGGCGGGGACCGTGGAGGCTTCCGAGGGGGCCGGGGTGGTGGGGACAGAGG TGGCTTTGGCCCTGGCAAGATGGATTCCAGGGGTGAGCACAGACAGGATCGCAGGGAGAGGCCGTATTAATTAGCCTGGCTCCCCAGGTT CTGGAACAGCTTTTTGTCCTGTACCCAGTGTTACCCTCGTTATTTTGTAACCTTCCAATTCCTGATCACCCAAGGGTTTTTTTGTGTCGG >In-frame_ENST00000369556_ENST00000568685_TCGA-CD-8527-01A_SLC35A1_chr6_88182737_+_FUS_chr16_31199646_length(amino acids)=285AA_start in transcript=22_stop in transcript=879 MRGGAEGAGVSSAGGCRGTMAAPRGPRDQGSRHDSAEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETG KLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQ RAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKM -------------------------------------------------------------- >In-frame_ENST00000369552_ENST00000254108_TCGA-CD-8527-01A_SLC35A1_chr6_88182737_+_FUS_chr16_31199646_length(transcript)=1193nt_BP=43nt AGTTCCGCGGGGGGCTGTCGGGGAACCATGGCTGCCCCGAGAGGCCCTCGGGACCAAGGATCACGTCATGACTCCGAACAGGATAATTCA GACAACAACACCATCTTTGTGCAAGGCCTGGGTGAGAATGTTACAATTGAGTCTGTGGCTGATTACTTCAAGCAGATTGGTATTATTAAG ACAAACAAGAAAACGGGACAGCCCATGATTAATTTGTACACAGACAGGGAAACTGGCAAGCTGAAGGGAGAGGCAACGGTCTCTTTTGAT GACCCACCTTCAGCTAAAGCAGCTATTGACTGGTTTGATGGTAAAGAATTCTCCGGAAATCCTATCAAGGTCTCATTTGCTACTCGCCGG GCAGACTTTAATCGGGGTGGTGGCAATGGTCGTGGAGGCCGAGGGCGAGGAGGACCCATGGGCCGTGGAGGCTATGGAGGTGGTGGCAGT GGTGGTGGTGGCCGAGGAGGATTTCCCAGTGGAGGTGGTGGCGGTGGAGGACAGCAGCGAGCTGGTGACTGGAAGTGTCCTAATCCCACC TGTGAGAATATGAACTTCTCTTGGAGGAATGAATGCAACCAGTGTAAGGCCCCTAAACCAGATGGCCCAGGAGGGGGACCAGGTGGCTCT CACATGGGGGGTAACTACGGGGATGATCGTCGTGGTGGCAGAGGAGGCTATGATCGAGGCGGCTACCGGGGCCGCGGCGGGGACCGTGGA GGCTTCCGAGGGGGCCGGGGTGGTGGGGACAGAGGTGGCTTTGGCCCTGGCAAGATGGATTCCAGGGGTGAGCACAGACAGGATCGCAGG GAGAGGCCGTATTAATTAGCCTGGCTCCCCAGGTTCTGGAACAGCTTTTTGTCCTGTACCCAGTGTTACCCTCGTTATTTTGTAACCTTC CAATTCCTGATCACCCAAGGGTTTTTTTGTGTCGGACTATGTAATTGTAACTATACCTCTGGTTCCCATTAAAAGTGACCATTTTAGTTA AATTTTGTTCCTCTTCCCCCTTTTCACTTTCCTGGAAGATCGATGTCCCGATCAGGAAGGTAGAGAGTTTTCCTGTTCAGATTACCCTGC CCAGCAGGAACTGGAATACAGTGTTCGGGGAGAAGGCCAAATGATATCCTTGAGAGCAGAGATTAAACTTTTCTGTCATGGGGAAAGTTG >In-frame_ENST00000369552_ENST00000254108_TCGA-CD-8527-01A_SLC35A1_chr6_88182737_+_FUS_chr16_31199646_length(amino acids)=265AA_start in transcript=27_stop in transcript=824 MAAPRGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAI DWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWR -------------------------------------------------------------- >In-frame_ENST00000369552_ENST00000380244_TCGA-CD-8527-01A_SLC35A1_chr6_88182737_+_FUS_chr16_31199646_length(transcript)=989nt_BP=43nt AGTTCCGCGGGGGGCTGTCGGGGAACCATGGCTGCCCCGAGAGGCCCTCGGGACCAAGGATCACGTCATGACTCCGAACAGGATAATTCA GACAACAACACCATCTTTGTGCAAGGCCTGGGTGAGAATGTTACAATTGAGTCTGTGGCTGATTACTTCAAGCAGATTGGTATTATTAAG ACAAACAAGAAAACGGGACAGCCCATGATTAATTTGTACACAGACAGGGAAACTGGCAAGCTGAAGGGAGAGGCAACGGTCTCTTTTGAT GACCCACCTTCAGCTAAAGCAGCTATTGACTGGTTTGATGGTAAAGAATTCTCCGGAAATCCTATCAAGGTCTCATTTGCTACTCGCCGG GCAGACTTTAATCGGGGTGGTGGCAATGGTCGTGGAGGCCGAGGGCGAGGAGGACCCATGGGCCGTGGAGGCTATGGAGGTGGTGGCAGT GGTGGTGGTGGCCGAGGAGGATTTCCCAGTGGAGGTGGTGGCGGTGGAGGACAGCAGCGAGCTGGTGACTGGAAGTGTCCTAATCCCACC TGTGAGAATATGAACTTCTCTTGGAGGAATGAATGCAACCAGTGTAAGGCCCCTAAACCAGATGGCCCAGGAGGGGGACCAGGTGGCTCT CACATGGGGGGTAACTACGGGGATGATCGTCGTGGTGGCAGAGGAGGCTATGATCGAGGCGGCTACCGGGGCCGCGGCGGGGACCGTGGA GGCTTCCGAGGGGGCCGGGGTGGTGGGGACAGAGGTGGCTTTGGCCCTGGCAAGATGGATTCCAGGGGTGAGCACAGACAGGATCGCAGG GAGAGGCCGTATTAATTAGCCTGGCTCCCCAGGTTCTGGAACAGCTTTTTGTCCTGTACCCAGTGTTACCCTCGTTATTTTGTAACCTTC >In-frame_ENST00000369552_ENST00000380244_TCGA-CD-8527-01A_SLC35A1_chr6_88182737_+_FUS_chr16_31199646_length(amino acids)=265AA_start in transcript=27_stop in transcript=824 MAAPRGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAI DWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWR -------------------------------------------------------------- >In-frame_ENST00000369552_ENST00000568685_TCGA-CD-8527-01A_SLC35A1_chr6_88182737_+_FUS_chr16_31199646_length(transcript)=965nt_BP=43nt AGTTCCGCGGGGGGCTGTCGGGGAACCATGGCTGCCCCGAGAGGCCCTCGGGACCAAGGATCACGTCATGACTCCGCAGAACAGGATAAT TCAGACAACAACACCATCTTTGTGCAAGGCCTGGGTGAGAATGTTACAATTGAGTCTGTGGCTGATTACTTCAAGCAGATTGGTATTATT AAGACAAACAAGAAAACGGGACAGCCCATGATTAATTTGTACACAGACAGGGAAACTGGCAAGCTGAAGGGAGAGGCAACGGTCTCTTTT GATGACCCACCTTCAGCTAAAGCAGCTATTGACTGGTTTGATGGTAAAGAATTCTCCGGAAATCCTATCAAGGTCTCATTTGCTACTCGC CGGGCAGACTTTAATCGGGGTGGTGGCAATGGTCGTGGAGGCCGAGGGCGAGGAGGACCCATGGGCCGTGGAGGCTATGGAGGTGGTGGC AGTGGTGGTGGTGGCCGAGGAGGATTTCCCAGTGGAGGTGGTGGCGGTGGAGGACAGCAGCGAGCTGGTGACTGGAAGTGTCCTAATCCC ACCTGTGAGAATATGAACTTCTCTTGGAGGAATGAATGCAACCAGTGTAAGGCCCCTAAACCAGATGGCCCAGGAGGGGGACCAGGTGGC TCTCACATGGGGGGTAACTACGGGGATGATCGTCGTGGTGGCAGAGGAGGCTATGATCGAGGCGGCTACCGGGGCCGCGGCGGGGACCGT GGAGGCTTCCGAGGGGGCCGGGGTGGTGGGGACAGAGGTGGCTTTGGCCCTGGCAAGATGGATTCCAGGGGTGAGCACAGACAGGATCGC AGGGAGAGGCCGTATTAATTAGCCTGGCTCCCCAGGTTCTGGAACAGCTTTTTGTCCTGTACCCAGTGTTACCCTCGTTATTTTGTAACC >In-frame_ENST00000369552_ENST00000568685_TCGA-CD-8527-01A_SLC35A1_chr6_88182737_+_FUS_chr16_31199646_length(amino acids)=266AA_start in transcript=27_stop in transcript=827 MAAPRGPRDQGSRHDSAEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAA IDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSW -------------------------------------------------------------- >In-frame_ENST00000369557_ENST00000254108_TCGA-CD-8527-01A_SLC35A1_chr6_88182737_+_FUS_chr16_31199646_length(transcript)=1166nt_BP=16nt ATGGCTGCCCCGAGAGGCCCTCGGGACCAAGGATCACGTCATGACTCCGAACAGGATAATTCAGACAACAACACCATCTTTGTGCAAGGC CTGGGTGAGAATGTTACAATTGAGTCTGTGGCTGATTACTTCAAGCAGATTGGTATTATTAAGACAAACAAGAAAACGGGACAGCCCATG ATTAATTTGTACACAGACAGGGAAACTGGCAAGCTGAAGGGAGAGGCAACGGTCTCTTTTGATGACCCACCTTCAGCTAAAGCAGCTATT GACTGGTTTGATGGTAAAGAATTCTCCGGAAATCCTATCAAGGTCTCATTTGCTACTCGCCGGGCAGACTTTAATCGGGGTGGTGGCAAT GGTCGTGGAGGCCGAGGGCGAGGAGGACCCATGGGCCGTGGAGGCTATGGAGGTGGTGGCAGTGGTGGTGGTGGCCGAGGAGGATTTCCC AGTGGAGGTGGTGGCGGTGGAGGACAGCAGCGAGCTGGTGACTGGAAGTGTCCTAATCCCACCTGTGAGAATATGAACTTCTCTTGGAGG AATGAATGCAACCAGTGTAAGGCCCCTAAACCAGATGGCCCAGGAGGGGGACCAGGTGGCTCTCACATGGGGGGTAACTACGGGGATGAT CGTCGTGGTGGCAGAGGAGGCTATGATCGAGGCGGCTACCGGGGCCGCGGCGGGGACCGTGGAGGCTTCCGAGGGGGCCGGGGTGGTGGG GACAGAGGTGGCTTTGGCCCTGGCAAGATGGATTCCAGGGGTGAGCACAGACAGGATCGCAGGGAGAGGCCGTATTAATTAGCCTGGCTC CCCAGGTTCTGGAACAGCTTTTTGTCCTGTACCCAGTGTTACCCTCGTTATTTTGTAACCTTCCAATTCCTGATCACCCAAGGGTTTTTT TGTGTCGGACTATGTAATTGTAACTATACCTCTGGTTCCCATTAAAAGTGACCATTTTAGTTAAATTTTGTTCCTCTTCCCCCTTTTCAC TTTCCTGGAAGATCGATGTCCCGATCAGGAAGGTAGAGAGTTTTCCTGTTCAGATTACCCTGCCCAGCAGGAACTGGAATACAGTGTTCG >In-frame_ENST00000369557_ENST00000254108_TCGA-CD-8527-01A_SLC35A1_chr6_88182737_+_FUS_chr16_31199646_length(amino acids)=265AA_start in transcript=0_stop in transcript=797 MAAPRGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAI DWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWR -------------------------------------------------------------- >In-frame_ENST00000369557_ENST00000380244_TCGA-CD-8527-01A_SLC35A1_chr6_88182737_+_FUS_chr16_31199646_length(transcript)=962nt_BP=16nt ATGGCTGCCCCGAGAGGCCCTCGGGACCAAGGATCACGTCATGACTCCGAACAGGATAATTCAGACAACAACACCATCTTTGTGCAAGGC CTGGGTGAGAATGTTACAATTGAGTCTGTGGCTGATTACTTCAAGCAGATTGGTATTATTAAGACAAACAAGAAAACGGGACAGCCCATG ATTAATTTGTACACAGACAGGGAAACTGGCAAGCTGAAGGGAGAGGCAACGGTCTCTTTTGATGACCCACCTTCAGCTAAAGCAGCTATT GACTGGTTTGATGGTAAAGAATTCTCCGGAAATCCTATCAAGGTCTCATTTGCTACTCGCCGGGCAGACTTTAATCGGGGTGGTGGCAAT GGTCGTGGAGGCCGAGGGCGAGGAGGACCCATGGGCCGTGGAGGCTATGGAGGTGGTGGCAGTGGTGGTGGTGGCCGAGGAGGATTTCCC AGTGGAGGTGGTGGCGGTGGAGGACAGCAGCGAGCTGGTGACTGGAAGTGTCCTAATCCCACCTGTGAGAATATGAACTTCTCTTGGAGG AATGAATGCAACCAGTGTAAGGCCCCTAAACCAGATGGCCCAGGAGGGGGACCAGGTGGCTCTCACATGGGGGGTAACTACGGGGATGAT CGTCGTGGTGGCAGAGGAGGCTATGATCGAGGCGGCTACCGGGGCCGCGGCGGGGACCGTGGAGGCTTCCGAGGGGGCCGGGGTGGTGGG GACAGAGGTGGCTTTGGCCCTGGCAAGATGGATTCCAGGGGTGAGCACAGACAGGATCGCAGGGAGAGGCCGTATTAATTAGCCTGGCTC CCCAGGTTCTGGAACAGCTTTTTGTCCTGTACCCAGTGTTACCCTCGTTATTTTGTAACCTTCCAATTCCTGATCACCCAAGGGTTTTTT >In-frame_ENST00000369557_ENST00000380244_TCGA-CD-8527-01A_SLC35A1_chr6_88182737_+_FUS_chr16_31199646_length(amino acids)=265AA_start in transcript=0_stop in transcript=797 MAAPRGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAI DWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWR -------------------------------------------------------------- >In-frame_ENST00000369557_ENST00000568685_TCGA-CD-8527-01A_SLC35A1_chr6_88182737_+_FUS_chr16_31199646_length(transcript)=938nt_BP=16nt ATGGCTGCCCCGAGAGGCCCTCGGGACCAAGGATCACGTCATGACTCCGCAGAACAGGATAATTCAGACAACAACACCATCTTTGTGCAA GGCCTGGGTGAGAATGTTACAATTGAGTCTGTGGCTGATTACTTCAAGCAGATTGGTATTATTAAGACAAACAAGAAAACGGGACAGCCC ATGATTAATTTGTACACAGACAGGGAAACTGGCAAGCTGAAGGGAGAGGCAACGGTCTCTTTTGATGACCCACCTTCAGCTAAAGCAGCT ATTGACTGGTTTGATGGTAAAGAATTCTCCGGAAATCCTATCAAGGTCTCATTTGCTACTCGCCGGGCAGACTTTAATCGGGGTGGTGGC AATGGTCGTGGAGGCCGAGGGCGAGGAGGACCCATGGGCCGTGGAGGCTATGGAGGTGGTGGCAGTGGTGGTGGTGGCCGAGGAGGATTT CCCAGTGGAGGTGGTGGCGGTGGAGGACAGCAGCGAGCTGGTGACTGGAAGTGTCCTAATCCCACCTGTGAGAATATGAACTTCTCTTGG AGGAATGAATGCAACCAGTGTAAGGCCCCTAAACCAGATGGCCCAGGAGGGGGACCAGGTGGCTCTCACATGGGGGGTAACTACGGGGAT GATCGTCGTGGTGGCAGAGGAGGCTATGATCGAGGCGGCTACCGGGGCCGCGGCGGGGACCGTGGAGGCTTCCGAGGGGGCCGGGGTGGT GGGGACAGAGGTGGCTTTGGCCCTGGCAAGATGGATTCCAGGGGTGAGCACAGACAGGATCGCAGGGAGAGGCCGTATTAATTAGCCTGG CTCCCCAGGTTCTGGAACAGCTTTTTGTCCTGTACCCAGTGTTACCCTCGTTATTTTGTAACCTTCCAATTCCTGATCACCCAAGGGTTT >In-frame_ENST00000369557_ENST00000568685_TCGA-CD-8527-01A_SLC35A1_chr6_88182737_+_FUS_chr16_31199646_length(amino acids)=266AA_start in transcript=0_stop in transcript=800 MAAPRGPRDQGSRHDSAEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAA IDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSW -------------------------------------------------------------- |
Top |
Fusion Gene PPI Analysis for SLC35A1-FUS |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
Related Drugs for SLC35A1-FUS |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
Related Diseases for SLC35A1-FUS |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | SLC35A1 | C1970344 | Congenital Disorder Of Glycosylation, Type IIF | 3 | CTD_human;GENOMICS_ENGLAND |
| Hgene | SLC35A1 | C0019080 | Hemorrhage | 1 | GENOMICS_ENGLAND |
| Hgene | SLC35A1 | C0036572 | Seizures | 1 | GENOMICS_ENGLAND |
| Hgene | SLC35A1 | C2751260 | Macrothrombocytopenia | 1 | GENOMICS_ENGLAND |
| Hgene | SLC35A1 | C4317224 | Congenital disorder of glycosylation type 1q | 1 | GENOMICS_ENGLAND |
| Tgene | FUS | C1842675 | AMYOTROPHIC LATERAL SCLEROSIS 6 (disorder) | 5 | UNIPROT |
| Tgene | FUS | C3468114 | Juvenile amyotrophic lateral sclerosis | 5 | ORPHANET |
| Tgene | FUS | C0002736 | Amyotrophic Lateral Sclerosis | 2 | CTD_human;ORPHANET |
| Tgene | FUS | C0206634 | Liposarcoma, Myxoid | 2 | CTD_human;ORPHANET |
| Tgene | FUS | C0393554 | Amyotrophic Lateral Sclerosis With Dementia | 1 | CTD_human |
| Tgene | FUS | C0497327 | Dementia | 1 | GENOMICS_ENGLAND |
| Tgene | FUS | C0543859 | Amyotrophic Lateral Sclerosis, Guam Form | 1 | CTD_human |
| Tgene | FUS | C3539195 | TREMOR, HEREDITARY ESSENTIAL, 4 | 1 | CTD_human;UNIPROT |
| Tgene | FUS | C3888102 | Frontotemporal Dementia With Motor Neuron Disease | 1 | ORPHANET |
Copyright 2021-Present -The University of Texas Health Science Center at Houston (UTHealth)
Web File Viewing | Emergency Information |Campus Carry|Site Policies