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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SLC6A17-DPYD (FusionGDB2 ID:82859)

Fusion Gene Summary for SLC6A17-DPYD

check button Fusion gene summary
Fusion gene informationFusion gene name: SLC6A17-DPYD
Fusion gene ID: 82859
HgeneTgene
Gene symbol

SLC6A17

DPYD

Gene ID

388662

1806

Gene namesolute carrier family 6 member 17dihydropyrimidine dehydrogenase
SynonymsMRT48|NTT4DHP|DHPDHASE|DPD
Cytomap

1p13.3

1p21.3

Type of geneprotein-codingprotein-coding
Descriptionsodium-dependent neutral amino acid transporter SLC6A17orphan sodium- and chloride-dependent neurotransmitter transporter NTT4dihydropyrimidine dehydrogenase [NADP(+)]dihydrothymine dehydrogenasedihydrouracil dehydrogenase
Modification date2020031320200313
UniProtAcc.

Q12882

Ensembl transtripts involved in fusion geneENST00000331565, ENST00000465159, 
ENST00000370192, ENST00000474241, 
ENST00000423006, ENST00000306031, 
Fusion gene scores* DoF score2 X 2 X 2=812 X 12 X 7=1008
# samples 213
** MAII scorelog2(2/8*10)=1.32192809488736log2(13/1008*10)=-2.95491211047146
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SLC6A17 [Title/Abstract] AND DPYD [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSLC6A17(110719361)-DPYD(97564188), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneDPYD

GO:0006210

thymine catabolic process

10410956

TgeneDPYD

GO:0006212

uracil catabolic process

1512248|18075467

TgeneDPYD

GO:0006214

thymidine catabolic process

1512248


check buttonFusion gene breakpoints across SLC6A17 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across DPYD (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SKCMTCGA-EB-A82C-01ASLC6A17chr1

110719361

-DPYDchr1

97564188

-


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Fusion Gene ORF analysis for SLC6A17-DPYD

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000331565ENST00000370192SLC6A17chr1

110719361

-DPYDchr1

97564188

-
5CDS-intronENST00000331565ENST00000474241SLC6A17chr1

110719361

-DPYDchr1

97564188

-
5CDS-intronENST00000331565ENST00000423006SLC6A17chr1

110719361

-DPYDchr1

97564188

-
5CDS-intronENST00000331565ENST00000306031SLC6A17chr1

110719361

-DPYDchr1

97564188

-
intron-3CDSENST00000465159ENST00000370192SLC6A17chr1

110719361

-DPYDchr1

97564188

-
intron-intronENST00000465159ENST00000474241SLC6A17chr1

110719361

-DPYDchr1

97564188

-
intron-intronENST00000465159ENST00000423006SLC6A17chr1

110719361

-DPYDchr1

97564188

-
intron-intronENST00000465159ENST00000306031SLC6A17chr1

110719361

-DPYDchr1

97564188

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000331565SLC6A17chr1110719361-ENST00000370192DPYDchr197564188-303813494431804453

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000331565ENST00000370192SLC6A17chr1110719361-DPYDchr197564188-0.0006230980.99937695

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Fusion Genomic Features for SLC6A17-DPYD


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SLC6A17-DPYD


check button Go to

FGviewer for the breakpoints of chr1:110719361-chr1:97564188

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.DPYD

Q12882

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLC6A17chr1:110719361chr1:97564188ENST00000331565-612117_147288.0728.0Topological domainCytoplasmic
HgeneSLC6A17chr1:110719361chr1:97564188ENST00000331565-612169_222288.0728.0Topological domainExtracellular
HgeneSLC6A17chr1:110719361chr1:97564188ENST00000331565-6121_69288.0728.0Topological domainCytoplasmic
HgeneSLC6A17chr1:110719361chr1:97564188ENST00000331565-612244_253288.0728.0Topological domainCytoplasmic
HgeneSLC6A17chr1:110719361chr1:97564188ENST00000331565-61291_95288.0728.0Topological domainExtracellular
HgeneSLC6A17chr1:110719361chr1:97564188ENST00000331565-612148_168288.0728.0TransmembraneHelical%3B Name%3D3
HgeneSLC6A17chr1:110719361chr1:97564188ENST00000331565-612223_243288.0728.0TransmembraneHelical%3B Name%3D4
HgeneSLC6A17chr1:110719361chr1:97564188ENST00000331565-612254_274288.0728.0TransmembraneHelical%3B Name%3D5
HgeneSLC6A17chr1:110719361chr1:97564188ENST00000331565-61270_90288.0728.0TransmembraneHelical%3B Name%3D1
HgeneSLC6A17chr1:110719361chr1:97564188ENST00000331565-61296_116288.0728.0TransmembraneHelical%3B Name%3D2
TgeneDPYDchr1:110719361chr1:97564188ENST000003701921923944_976874.01026.0Domain4Fe-4S ferredoxin-type 2
TgeneDPYDchr1:110719361chr1:97564188ENST000003701921923978_1007874.01026.0Domain4Fe-4S ferredoxin-type 3

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLC6A17chr1:110719361chr1:97564188ENST00000331565-612275_300288.0728.0Topological domainExtracellular
HgeneSLC6A17chr1:110719361chr1:97564188ENST00000331565-612322_334288.0728.0Topological domainCytoplasmic
HgeneSLC6A17chr1:110719361chr1:97564188ENST00000331565-612356_460288.0728.0Topological domainExtracellular
HgeneSLC6A17chr1:110719361chr1:97564188ENST00000331565-612482_490288.0728.0Topological domainCytoplasmic
HgeneSLC6A17chr1:110719361chr1:97564188ENST00000331565-612512_527288.0728.0Topological domainExtracellular
HgeneSLC6A17chr1:110719361chr1:97564188ENST00000331565-612549_573288.0728.0Topological domainCytoplasmic
HgeneSLC6A17chr1:110719361chr1:97564188ENST00000331565-612595_617288.0728.0Topological domainExtracellular
HgeneSLC6A17chr1:110719361chr1:97564188ENST00000331565-612639_727288.0728.0Topological domainCytoplasmic
HgeneSLC6A17chr1:110719361chr1:97564188ENST00000331565-612301_321288.0728.0TransmembraneHelical%3B Name%3D6
HgeneSLC6A17chr1:110719361chr1:97564188ENST00000331565-612335_355288.0728.0TransmembraneHelical%3B Name%3D7
HgeneSLC6A17chr1:110719361chr1:97564188ENST00000331565-612461_481288.0728.0TransmembraneHelical%3B Name%3D8
HgeneSLC6A17chr1:110719361chr1:97564188ENST00000331565-612491_511288.0728.0TransmembraneHelical%3B Name%3D9
HgeneSLC6A17chr1:110719361chr1:97564188ENST00000331565-612528_548288.0728.0TransmembraneHelical%3B Name%3D10
HgeneSLC6A17chr1:110719361chr1:97564188ENST00000331565-612574_594288.0728.0TransmembraneHelical%3B Name%3D11
HgeneSLC6A17chr1:110719361chr1:97564188ENST00000331565-612618_638288.0728.0TransmembraneHelical%3B Name%3D12
TgeneDPYDchr1:110719361chr1:97564188ENST00000370192192369_100874.01026.0Domain4Fe-4S ferredoxin-type 1
TgeneDPYDchr1:110719361chr1:97564188ENST000003701921923194_198874.01026.0Nucleotide bindingFAD
TgeneDPYDchr1:110719361chr1:97564188ENST000003701921923218_226874.01026.0Nucleotide bindingFAD
TgeneDPYDchr1:110719361chr1:97564188ENST000003701921923340_343874.01026.0Nucleotide bindingNADP
TgeneDPYDchr1:110719361chr1:97564188ENST000003701921923364_365874.01026.0Nucleotide bindingNADP
TgeneDPYDchr1:110719361chr1:97564188ENST000003701921923437_439874.01026.0Nucleotide bindingNADP
TgeneDPYDchr1:110719361chr1:97564188ENST000003701921923480_489874.01026.0Nucleotide bindingFAD
TgeneDPYDchr1:110719361chr1:97564188ENST000003701921923481_487874.01026.0Nucleotide bindingNADP
TgeneDPYDchr1:110719361chr1:97564188ENST000003701921923574_575874.01026.0Nucleotide bindingFMN
TgeneDPYDchr1:110719361chr1:97564188ENST000003701921923793_795874.01026.0Nucleotide bindingFMN
TgeneDPYDchr1:110719361chr1:97564188ENST000003701921923816_817874.01026.0Nucleotide bindingFMN
TgeneDPYDchr1:110719361chr1:97564188ENST000003701921923668_670874.01026.0RegionSubstrate binding
TgeneDPYDchr1:110719361chr1:97564188ENST000003701921923736_737874.01026.0RegionSubstrate binding


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Fusion Gene Sequence for SLC6A17-DPYD


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000331565_ENST00000370192_TCGA-EB-A82C-01A_SLC6A17_chr1_110719361_-_DPYD_chr1_97564188_length(transcript)=3038nt_BP=1349nt
AGGGTGGCCTTTCGGAAAGCGAGGGAACAGTGCGCGCAGCGCTCCGCCCAGCTCCGTTCTGCTCCGCAGAGCCGGCGCTGCCAGGGCGCA
GGGAGGGCGGCACTCGGCCCCAGTCTTCGCAATCCCGCGCGCTCTCTCCGCCGTGGGACCTGGGTCCCCGCGCCGCTCCCCTGAGCCCCG
AGCGCGCGGCGGGCGGGAGCCAGGTTGGGACTGGTGGTGAGGCAGGGAGTGAGGAGCGAGCGGAGTCGCGTGCGCCGGCGCGCAGCTCCG
GGTCGCCCCAGCCCCAGCCGGGGGCCTGTGGCCCGGGGGAGGAGCTGTGCGTCCGCGACCCGTCGGGGATCGCAGCTGCTCGGCCGGAGT
GCACGGGCCGAGTCTGCGCGACTACCCACGCGTGACAGGTCCCTGAATGAGAAGGAGCTGACAGCAGCTGAATTCCATCTTCTCTGTGTG
CTGGGGAGCAGGGCTACACGGCCCAGGTGGCATCAATGCCGAAGAACAGCAAAGTGACCCAGCGTGAGCACAGCAGTGAGCATGTCACTG
AGTCCGTGGCCGACCTGCTGGCCCTCGAGGAGCCTGTGGACTATAAGCAGAGTGTACTGAATGTGGCTGGTGAGGCAGGCGGCAAGCAGA
AGGCGGTGGAGGAGGAGCTGGATGCAGAGGACCGGCCGGCCTGGAACAGTAAGCTGCAGTACATCCTGGCCCAGATTGGCTTCTCTGTGG
GCCTCGGCAACATCTGGAGGTTCCCCTACCTGTGCCAGAAAAATGGAGGAGGTGCTTACCTGGTGCCCTACCTGGTGCTGCTGATCATCA
TCGGGATCCCCCTCTTCTTCCTGGAGCTGGCTGTGGGTCAGAGGATCCGCCGCGGCAGCATCGGTGTGTGGCACTATATATGTCCCCGCC
TGGGGGGCATCGGCTTCTCCAGCTGCATAGTCTGTCTCTTTGTGGGGCTGTATTATAATGTGATCATCGGGTGGAGCATCTTCTATTTCT
TCAAGTCCTTCCAGTACCCGCTGCCCTGGAGTGAATGTCCTGTCGTCAGGAATGGGAGCGTGGCAGTGGTGGAGGCAGAGTGTGAAAAGA
GCTCAGCCACTACCTACTTCTGGTACCGAGAGGCCTTGGACATCTCTGACTCCATCTCGGAGAGTGGGGGCCTCAACTGGAAGATGACCC
TGTGCCTCCTCGTGGCCTGGAGCATCGTGGGGATGGCTGTCGTTAAGGGCATCCAGTCCTCGGGGAAGGTGATGTATTTCAGCTCCCTCT
TCCCCTACGTGGTGCTGGCCTGCTTCCTGGTCCGGGGGCTGTTGCTGCGAGGGGCAGTTGATGGCATCCTACACATGTTCACTCCCAAGA
AACTGCCAAGTTTTGGACCTTATCTGGAACAGCGCAAGAAAATCATAGCAGAAAACAAGATTAGACTGAAAGAACAAAATGTAGCTTTTT
CACCACTTAAGAGAAACTGTTTTATCCCCAAAAGGCCTATTCCTACCATCAAGGATGTAATAGGAAAAGCACTGCAGTACCTTGGAACAT
TTGGTGAATTGAGCAACGTAGAGCAAGTTGTGGCTATGATTGATGAAGAAATGTGTATCAACTGTGGTAAATGCTACATGACCTGTAATG
ATTCTGGCTACCAGGCTATACAGTTTGATCCAGAAACCCACCTGCCCACCATAACCGACACTTGTACAGGCTGTACTCTGTGTCTCAGTG
TTTGCCCTATTGTCGACTGCATCAAAATGGTTTCCAGGACAACACCTTATGAACCAAAGAGAGGCGTACCCTTATCTGTGAATCCGGTGT
GTTAAGGTGATTTGTGAAACAGTTGCTGTGAACTTTCATGTCACCTACATATGCTGATCTTTTAAAATCATGATCCTTGTGTTCAGCTCT
TTCCAAATTAAAACAAATATACATTTTCTAAATAAAAATATGTAATTTCAAAATACATTTGTAAGTGTAAAAAATGTCTCATGTCAATGA
CCATTCAATTAGTGGTCATAAAATAGAATAATTCTTTTCTGAGGATAGTAGTTAAATAACTGTGTGGCAGTTAATTGGATGTTCACTGCC
AGTTGTCTTATGTGAAAAATTAACTTTTTTGTGGCAATTAGTGTGACAGTTTCCAAATTGCCCTATGCTGTGCTCCATATTTGATTTCTA
ATTGTAAGTGAAATTAAGCATTTTGAAACAAAGTACTCTTTAACATACAAGAAAATGTATCCAAGGAAACATTTTATCATTAAAAATTAC
CTTTAATTTTAATGCTGTTTCTAAGAAAATGTAGTTAGCTCCATAAAGTACAAATGAAGAAAGTCAAAAAATTATTTGCTATGGCAGGAT
AAGAAAGCCTAAAATTGAGTTTGTAGAACTTTATTAAGTAAAATCCCCTTCGCTGAAATTGCTTATTTTTGGTGTTGGATAGAGGATAGG
GAGAATATTTACTAACTAAATACCATTCACTACTCATGCGTGAGATGGGTGTACAAACTCATCCTCTTTTAATGGCATTTCTCTTTAAAC
TATGTTCCTAACAAAATGAGATGATAGGATAGATCCTGGTTACCACTCTTTTGCTGTGCACATACGGGCTCTGACTGGTTTTAATAGTCA
CCTTCATGATTATAGCAACTAATGTTTGAACAAAGCTCAAAGTATGCAATGCTTCATTATTCAAGAATGAAAAATATAATGTTGATAATA
TATATTAAGTGTGCCAAATCAGTTTGACTACTCTCTGTTTTAGTGTTTATGTTTAAAAGAAATATATTTTTTGTTATTATTAGATAATAT
TTTTGTATTTCTCTATTTTCATAATCAGTAAATAGTGTCATATAAACTCATTTATCTCCTCTTCATGGCATCTTCAATATGAATCTATAA
GTAGTAAATCAGAAAGTAACAATCTATGGCTTATTTCTATGACAAATTCAAGAGCTAGAAAAATAAAATGTTTCATTATGCACTTTTAGA

>In-frame_ENST00000331565_ENST00000370192_TCGA-EB-A82C-01A_SLC6A17_chr1_110719361_-_DPYD_chr1_97564188_length(amino acids)=453AA_start in transcript=443_stop in transcript=1804
MCAGEQGYTAQVASMPKNSKVTQREHSSEHVTESVADLLALEEPVDYKQSVLNVAGEAGGKQKAVEEELDAEDRPAWNSKLQYILAQIGF
SVGLGNIWRFPYLCQKNGGGAYLVPYLVLLIIIGIPLFFLELAVGQRIRRGSIGVWHYICPRLGGIGFSSCIVCLFVGLYYNVIIGWSIF
YFFKSFQYPLPWSECPVVRNGSVAVVEAECEKSSATTYFWYREALDISDSISESGGLNWKMTLCLLVAWSIVGMAVVKGIQSSGKVMYFS
SLFPYVVLACFLVRGLLLRGAVDGILHMFTPKKLPSFGPYLEQRKKIIAENKIRLKEQNVAFSPLKRNCFIPKRPIPTIKDVIGKALQYL
GTFGELSNVEQVVAMIDEEMCINCGKCYMTCNDSGYQAIQFDPETHLPTITDTCTGCTLCLSVCPIVDCIKMVSRTTPYEPKRGVPLSVN

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Fusion Gene PPI Analysis for SLC6A17-DPYD


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SLC6A17-DPYD


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
TgeneDPYDQ12882DB03147Flavin adenine dinucleotideSmall moleculeApproved
TgeneDPYDQ12882DB09257GimeracilInhibitorSmall moleculeApproved
TgeneDPYDQ12882DB03247Flavin mononucleotideSmall moleculeApproved|Investigational
TgeneDPYDQ12882DB09327Tegafur-uracilAntagonistSmall moleculeApproved|Investigational

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Related Diseases for SLC6A17-DPYD


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneSLC6A17C4225395MENTAL RETARDATION, AUTOSOMAL RECESSIVE 481CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneDPYDC1959620Dihydropyrimidine Dehydrogenase Deficiency7CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneDPYDC0009402Colorectal Carcinoma5CTD_human
TgeneDPYDC0009404Colorectal Neoplasms5CTD_human
TgeneDPYDC0024623Malignant neoplasm of stomach3CTD_human
TgeneDPYDC0038356Stomach Neoplasms3CTD_human
TgeneDPYDC1708349Hereditary Diffuse Gastric Cancer3CTD_human
TgeneDPYDC0030297Pancreatic Neoplasm2CTD_human
TgeneDPYDC0034139Purine-Pyrimidine Metabolism, Inborn Errors2CTD_human
TgeneDPYDC0036341Schizophrenia2CTD_human
TgeneDPYDC0346647Malignant neoplasm of pancreas2CTD_human
TgeneDPYDC1510586Autism Spectrum Disorders2CTD_human
TgeneDPYDC3495551Dihydropyrimidinuria2CTD_human
TgeneDPYDC43045781p21.3 microdeletion syndrome2ORPHANET
TgeneDPYDC0004352Autistic Disorder1CTD_human
TgeneDPYDC0006142Malignant neoplasm of breast1CTD_human
TgeneDPYDC0007102Malignant tumor of colon1CTD_human
TgeneDPYDC0009375Colonic Neoplasms1CTD_human
TgeneDPYDC0018671Head and Neck Neoplasms1CTD_human
TgeneDPYDC0018675Head Neoplasms1CTD_human
TgeneDPYDC0023012Language Delay1CTD_human
TgeneDPYDC0023014Language Development Disorders1CTD_human
TgeneDPYDC0024121Lung Neoplasms1CTD_human
TgeneDPYDC0027533Neck Neoplasms1CTD_human
TgeneDPYDC0027627Neoplasm Metastasis1CTD_human
TgeneDPYDC0027765nervous system disorder1CTD_human
TgeneDPYDC0027947Neutropenia1CTD_human
TgeneDPYDC0028754Obesity1CTD_human
TgeneDPYDC0241210Speech Delay1CTD_human
TgeneDPYDC0242379Malignant neoplasm of lung1CTD_human
TgeneDPYDC0270612Leukoencephalopathy1CTD_human
TgeneDPYDC0278996Malignant Head and Neck Neoplasm1CTD_human
TgeneDPYDC0454655Semantic-Pragmatic Disorder1CTD_human
TgeneDPYDC0678222Breast Carcinoma1CTD_human
TgeneDPYDC0746787Cancer of Neck1CTD_human
TgeneDPYDC0751177Cancer of Head1CTD_human
TgeneDPYDC0751257Auditory Processing Disorder, Central1CTD_human
TgeneDPYDC0887900Upper Aerodigestive Tract Neoplasms1CTD_human
TgeneDPYDC1257931Mammary Neoplasms, Human1CTD_human
TgeneDPYDC1458155Mammary Neoplasms1CTD_human
TgeneDPYDC1858991Childhood Ataxia with Central Nervous System Hypomyelinization1CTD_human
TgeneDPYDC2239176Liver carcinoma1CTD_human
TgeneDPYDC4704874Mammary Carcinoma, Human1CTD_human
TgeneDPYDC4721453Peripheral Nervous System Diseases1CTD_human