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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:SMG1-ANO3 (FusionGDB2 ID:83474) |
Fusion Gene Summary for SMG1-ANO3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SMG1-ANO3 | Fusion gene ID: 83474 | Hgene | Tgene | Gene symbol | SMG1 | ANO3 | Gene ID | 23049 | 63982 |
| Gene name | SMG1 nonsense mediated mRNA decay associated PI3K related kinase | anoctamin 3 | |
| Synonyms | 61E3.4|ATX|LIP | C11orf25|DYT23|DYT24|GENX-3947|TMEM16C | |
| Cytomap | 16p12.3 | 11p14.3-p14.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | serine/threonine-protein kinase SMG1PI-3-kinase-related kinase SMG-1SMG1 phosphatidylinositol 3-kinase-related kinaselambda-interacting proteinlambda/iota protein kinase C-interacting proteinsmg-1 homolog, phosphatidylinositol 3-kinase-related kinase | anoctamin-3dystonia 23transmembrane protein 16C (eight membrane-spanning domains) | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | Q9BYT9 | |
| Ensembl transtripts involved in fusion gene | ENST00000389467, ENST00000446231, ENST00000565224, ENST00000567737, | ENST00000537978, ENST00000525139, ENST00000256737, ENST00000531646, ENST00000531568, ENST00000529242, | |
| Fusion gene scores | * DoF score | 28 X 23 X 9=5796 | 11 X 9 X 5=495 |
| # samples | 31 | 12 | |
| ** MAII score | log2(31/5796*10)=-4.22471747428269 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(12/495*10)=-2.04439411935845 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SMG1 [Title/Abstract] AND ANO3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | SMG1(18869492)-ANO3(26669256), # samples:3 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | SMG1 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 11544179 |
| Hgene | SMG1 | GO:0018105 | peptidyl-serine phosphorylation | 11544179|15175154 |
| Hgene | SMG1 | GO:0046777 | protein autophosphorylation | 11331269|11544179 |
| Hgene | SMG1 | GO:0046854 | phosphatidylinositol phosphorylation | 11331269 |
| Hgene | SMG1 | GO:2001020 | regulation of response to DNA damage stimulus | 15175154 |
| Fusion gene breakpoints across SMG1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene breakpoints across ANO3 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | BRCA | TCGA-A2-A0EY-01A | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| ChimerDB4 | BRCA | TCGA-A2-A0EY | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + |
| ChimerDB4 | BRCA | TCGA-A2-A0EY-01A | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| ChimerDB4 | BRCA | TCGA-A2-A0EY-01A | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
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Fusion Gene ORF analysis for SMG1-ANO3 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000389467 | ENST00000537978 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| In-frame | ENST00000389467 | ENST00000525139 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| In-frame | ENST00000389467 | ENST00000256737 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| 5CDS-intron | ENST00000389467 | ENST00000531646 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| 5CDS-intron | ENST00000389467 | ENST00000531568 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| 5CDS-intron | ENST00000389467 | ENST00000529242 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| In-frame | ENST00000446231 | ENST00000537978 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| In-frame | ENST00000446231 | ENST00000525139 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| In-frame | ENST00000446231 | ENST00000256737 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| 5CDS-intron | ENST00000446231 | ENST00000531646 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| 5CDS-intron | ENST00000446231 | ENST00000531568 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| 5CDS-intron | ENST00000446231 | ENST00000529242 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| intron-3CDS | ENST00000565224 | ENST00000537978 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| intron-3CDS | ENST00000565224 | ENST00000525139 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| intron-3CDS | ENST00000565224 | ENST00000256737 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| intron-intron | ENST00000565224 | ENST00000531646 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| intron-intron | ENST00000565224 | ENST00000531568 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| intron-intron | ENST00000565224 | ENST00000529242 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| intron-3CDS | ENST00000567737 | ENST00000537978 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| intron-3CDS | ENST00000567737 | ENST00000525139 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| intron-3CDS | ENST00000567737 | ENST00000256737 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| intron-intron | ENST00000567737 | ENST00000531646 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| intron-intron | ENST00000567737 | ENST00000531568 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| intron-intron | ENST00000567737 | ENST00000529242 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| In-frame | ENST00000389467 | ENST00000537978 | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + |
| In-frame | ENST00000389467 | ENST00000525139 | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + |
| In-frame | ENST00000389467 | ENST00000256737 | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + |
| 5CDS-intron | ENST00000389467 | ENST00000531646 | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + |
| 5CDS-intron | ENST00000389467 | ENST00000531568 | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + |
| 5CDS-intron | ENST00000389467 | ENST00000529242 | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + |
| In-frame | ENST00000446231 | ENST00000537978 | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + |
| In-frame | ENST00000446231 | ENST00000525139 | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + |
| In-frame | ENST00000446231 | ENST00000256737 | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + |
| 5CDS-intron | ENST00000446231 | ENST00000531646 | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + |
| 5CDS-intron | ENST00000446231 | ENST00000531568 | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + |
| 5CDS-intron | ENST00000446231 | ENST00000529242 | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + |
| intron-3CDS | ENST00000565224 | ENST00000537978 | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + |
| intron-3CDS | ENST00000565224 | ENST00000525139 | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + |
| intron-3CDS | ENST00000565224 | ENST00000256737 | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + |
| intron-intron | ENST00000565224 | ENST00000531646 | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + |
| intron-intron | ENST00000565224 | ENST00000531568 | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + |
| intron-intron | ENST00000565224 | ENST00000529242 | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + |
| intron-3CDS | ENST00000567737 | ENST00000537978 | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + |
| intron-3CDS | ENST00000567737 | ENST00000525139 | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + |
| intron-3CDS | ENST00000567737 | ENST00000256737 | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + |
| intron-intron | ENST00000567737 | ENST00000531646 | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + |
| intron-intron | ENST00000567737 | ENST00000531568 | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + |
| intron-intron | ENST00000567737 | ENST00000529242 | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000389467 | SMG1 | chr16 | 18869492 | - | ENST00000537978 | ANO3 | chr11 | 26669256 | + | 5351 | 4597 | 153 | 5114 | 1653 |
| ENST00000389467 | SMG1 | chr16 | 18869492 | - | ENST00000525139 | ANO3 | chr11 | 26669256 | + | 5351 | 4597 | 153 | 5114 | 1653 |
| ENST00000389467 | SMG1 | chr16 | 18869492 | - | ENST00000256737 | ANO3 | chr11 | 26669256 | + | 7959 | 4597 | 153 | 5114 | 1653 |
| ENST00000446231 | SMG1 | chr16 | 18869492 | - | ENST00000537978 | ANO3 | chr11 | 26669256 | + | 5401 | 4647 | 203 | 5164 | 1653 |
| ENST00000446231 | SMG1 | chr16 | 18869492 | - | ENST00000525139 | ANO3 | chr11 | 26669256 | + | 5401 | 4647 | 203 | 5164 | 1653 |
| ENST00000446231 | SMG1 | chr16 | 18869492 | - | ENST00000256737 | ANO3 | chr11 | 26669256 | + | 8009 | 4647 | 203 | 5164 | 1653 |
| ENST00000389467 | SMG1 | chr16 | 18869491 | - | ENST00000537978 | ANO3 | chr11 | 26669255 | + | 5351 | 4597 | 153 | 5114 | 1653 |
| ENST00000389467 | SMG1 | chr16 | 18869491 | - | ENST00000525139 | ANO3 | chr11 | 26669255 | + | 5351 | 4597 | 153 | 5114 | 1653 |
| ENST00000389467 | SMG1 | chr16 | 18869491 | - | ENST00000256737 | ANO3 | chr11 | 26669255 | + | 7959 | 4597 | 153 | 5114 | 1653 |
| ENST00000446231 | SMG1 | chr16 | 18869491 | - | ENST00000537978 | ANO3 | chr11 | 26669255 | + | 5401 | 4647 | 203 | 5164 | 1653 |
| ENST00000446231 | SMG1 | chr16 | 18869491 | - | ENST00000525139 | ANO3 | chr11 | 26669255 | + | 5401 | 4647 | 203 | 5164 | 1653 |
| ENST00000446231 | SMG1 | chr16 | 18869491 | - | ENST00000256737 | ANO3 | chr11 | 26669255 | + | 8009 | 4647 | 203 | 5164 | 1653 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000389467 | ENST00000537978 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + | 0.000609931 | 0.99939 |
| ENST00000389467 | ENST00000525139 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + | 0.000609931 | 0.99939 |
| ENST00000389467 | ENST00000256737 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + | 0.000440958 | 0.999559 |
| ENST00000446231 | ENST00000537978 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + | 0.00066356 | 0.9993364 |
| ENST00000446231 | ENST00000525139 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + | 0.00066356 | 0.9993364 |
| ENST00000446231 | ENST00000256737 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + | 0.000472939 | 0.9995271 |
| ENST00000389467 | ENST00000537978 | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + | 0.000609931 | 0.99939 |
| ENST00000389467 | ENST00000525139 | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + | 0.000609931 | 0.99939 |
| ENST00000389467 | ENST00000256737 | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + | 0.000440958 | 0.999559 |
| ENST00000446231 | ENST00000537978 | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + | 0.00066356 | 0.9993364 |
| ENST00000446231 | ENST00000525139 | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + | 0.00066356 | 0.9993364 |
| ENST00000446231 | ENST00000256737 | SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + | 0.000472939 | 0.9995271 |
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Fusion Genomic Features for SMG1-ANO3 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + | 1.75E-05 | 0.9999825 |
| SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + | 1.75E-05 | 0.9999825 |
| SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + | 1.75E-05 | 0.9999825 |
| SMG1 | chr16 | 18869491 | - | ANO3 | chr11 | 26669255 | + | 1.75E-05 | 0.9999825 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for SMG1-ANO3 |
| Go to FGviewer for the breakpoints of chr16:18869492-chr11:26669256 - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | ANO3 |
| FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes. | FUNCTION: Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylcholine and galactosylceramide (By similarity). Seems to act as potassium channel regulator and may inhibit pain signaling; can facilitate KCNT1/Slack channel activity by promoting its full single-channel conductance at very low sodium concentrations and by increasing its sodium sensitivity (By similarity). Does not exhibit calcium-activated chloride channel (CaCC) activity (PubMed:21984732). {ECO:0000250|UniProtKB:A2AHL1, ECO:0000303|PubMed:21984732}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | ANO3 | chr16:18869491 | chr11:26669255 | ENST00000256737 | 22 | 27 | 832_914 | 809.3333333333334 | 982.0 | Topological domain | Extracellular | |
| Tgene | ANO3 | chr16:18869491 | chr11:26669255 | ENST00000256737 | 22 | 27 | 936_981 | 809.3333333333334 | 982.0 | Topological domain | Cytoplasmic | |
| Tgene | ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | 22 | 27 | 832_914 | 809.3333333333334 | 982.0 | Topological domain | Extracellular | |
| Tgene | ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | 22 | 27 | 936_981 | 809.3333333333334 | 982.0 | Topological domain | Cytoplasmic | |
| Tgene | ANO3 | chr16:18869491 | chr11:26669255 | ENST00000256737 | 22 | 27 | 811_831 | 809.3333333333334 | 982.0 | Transmembrane | Helical | |
| Tgene | ANO3 | chr16:18869491 | chr11:26669255 | ENST00000256737 | 22 | 27 | 915_935 | 809.3333333333334 | 982.0 | Transmembrane | Helical | |
| Tgene | ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | 22 | 27 | 811_831 | 809.3333333333334 | 982.0 | Transmembrane | Helical | |
| Tgene | ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | 22 | 27 | 915_935 | 809.3333333333334 | 982.0 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SMG1 | chr16:18869491 | chr11:26669255 | ENST00000446231 | - | 29 | 63 | 1283_1866 | 1411.3333333333333 | 3662.0 | Domain | FAT |
| Hgene | SMG1 | chr16:18869491 | chr11:26669255 | ENST00000446231 | - | 29 | 63 | 2150_2478 | 1411.3333333333333 | 3662.0 | Domain | PI3K/PI4K |
| Hgene | SMG1 | chr16:18869491 | chr11:26669255 | ENST00000446231 | - | 29 | 63 | 3629_3661 | 1411.3333333333333 | 3662.0 | Domain | FATC |
| Hgene | SMG1 | chr16:18869492 | chr11:26669256 | ENST00000446231 | - | 29 | 63 | 1283_1866 | 1411.3333333333333 | 3662.0 | Domain | FAT |
| Hgene | SMG1 | chr16:18869492 | chr11:26669256 | ENST00000446231 | - | 29 | 63 | 2150_2478 | 1411.3333333333333 | 3662.0 | Domain | PI3K/PI4K |
| Hgene | SMG1 | chr16:18869492 | chr11:26669256 | ENST00000446231 | - | 29 | 63 | 3629_3661 | 1411.3333333333333 | 3662.0 | Domain | FATC |
| Hgene | SMG1 | chr16:18869491 | chr11:26669255 | ENST00000446231 | - | 29 | 63 | 1817_1852 | 1411.3333333333333 | 3662.0 | Repeat | Note=HEAT |
| Hgene | SMG1 | chr16:18869492 | chr11:26669256 | ENST00000446231 | - | 29 | 63 | 1817_1852 | 1411.3333333333333 | 3662.0 | Repeat | Note=HEAT |
| Tgene | ANO3 | chr16:18869491 | chr11:26669255 | ENST00000256737 | 22 | 27 | 1_403 | 809.3333333333334 | 982.0 | Topological domain | Cytoplasmic | |
| Tgene | ANO3 | chr16:18869491 | chr11:26669255 | ENST00000256737 | 22 | 27 | 425_469 | 809.3333333333334 | 982.0 | Topological domain | Extracellular | |
| Tgene | ANO3 | chr16:18869491 | chr11:26669255 | ENST00000256737 | 22 | 27 | 491_550 | 809.3333333333334 | 982.0 | Topological domain | Cytoplasmic | |
| Tgene | ANO3 | chr16:18869491 | chr11:26669255 | ENST00000256737 | 22 | 27 | 572_592 | 809.3333333333334 | 982.0 | Topological domain | Extracellular | |
| Tgene | ANO3 | chr16:18869491 | chr11:26669255 | ENST00000256737 | 22 | 27 | 614_640 | 809.3333333333334 | 982.0 | Topological domain | Cytoplasmic | |
| Tgene | ANO3 | chr16:18869491 | chr11:26669255 | ENST00000256737 | 22 | 27 | 662_761 | 809.3333333333334 | 982.0 | Topological domain | Extracellular | |
| Tgene | ANO3 | chr16:18869491 | chr11:26669255 | ENST00000256737 | 22 | 27 | 783_810 | 809.3333333333334 | 982.0 | Topological domain | Cytoplasmic | |
| Tgene | ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | 22 | 27 | 1_403 | 809.3333333333334 | 982.0 | Topological domain | Cytoplasmic | |
| Tgene | ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | 22 | 27 | 425_469 | 809.3333333333334 | 982.0 | Topological domain | Extracellular | |
| Tgene | ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | 22 | 27 | 491_550 | 809.3333333333334 | 982.0 | Topological domain | Cytoplasmic | |
| Tgene | ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | 22 | 27 | 572_592 | 809.3333333333334 | 982.0 | Topological domain | Extracellular | |
| Tgene | ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | 22 | 27 | 614_640 | 809.3333333333334 | 982.0 | Topological domain | Cytoplasmic | |
| Tgene | ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | 22 | 27 | 662_761 | 809.3333333333334 | 982.0 | Topological domain | Extracellular | |
| Tgene | ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | 22 | 27 | 783_810 | 809.3333333333334 | 982.0 | Topological domain | Cytoplasmic | |
| Tgene | ANO3 | chr16:18869491 | chr11:26669255 | ENST00000256737 | 22 | 27 | 404_424 | 809.3333333333334 | 982.0 | Transmembrane | Helical | |
| Tgene | ANO3 | chr16:18869491 | chr11:26669255 | ENST00000256737 | 22 | 27 | 470_490 | 809.3333333333334 | 982.0 | Transmembrane | Helical | |
| Tgene | ANO3 | chr16:18869491 | chr11:26669255 | ENST00000256737 | 22 | 27 | 551_571 | 809.3333333333334 | 982.0 | Transmembrane | Helical | |
| Tgene | ANO3 | chr16:18869491 | chr11:26669255 | ENST00000256737 | 22 | 27 | 593_613 | 809.3333333333334 | 982.0 | Transmembrane | Helical | |
| Tgene | ANO3 | chr16:18869491 | chr11:26669255 | ENST00000256737 | 22 | 27 | 641_661 | 809.3333333333334 | 982.0 | Transmembrane | Helical | |
| Tgene | ANO3 | chr16:18869491 | chr11:26669255 | ENST00000256737 | 22 | 27 | 762_782 | 809.3333333333334 | 982.0 | Transmembrane | Helical | |
| Tgene | ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | 22 | 27 | 404_424 | 809.3333333333334 | 982.0 | Transmembrane | Helical | |
| Tgene | ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | 22 | 27 | 470_490 | 809.3333333333334 | 982.0 | Transmembrane | Helical | |
| Tgene | ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | 22 | 27 | 551_571 | 809.3333333333334 | 982.0 | Transmembrane | Helical | |
| Tgene | ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | 22 | 27 | 593_613 | 809.3333333333334 | 982.0 | Transmembrane | Helical | |
| Tgene | ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | 22 | 27 | 641_661 | 809.3333333333334 | 982.0 | Transmembrane | Helical | |
| Tgene | ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | 22 | 27 | 762_782 | 809.3333333333334 | 982.0 | Transmembrane | Helical |
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Fusion Gene Sequence for SMG1-ANO3 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >In-frame_ENST00000389467_ENST00000537978_TCGA-A2-A0EY-01A_SMG1_chr16_18869492_-_ANO3_chr11_26669256_length(transcript)=5351nt_BP=4597nt GCCGTGTGAGCGTGAGGAGCTGCCGCCACCGCCTGCTCCTCGTCGTCCTCGTCCTCCGGGGCCCCGGCGACGTGGGCCGCGCACGGCCCT GGAAAAGACGTCGCCTCCCCTTCATCCGCCTCTCTCTCACCGCGCCGCTCCCGCCTCCTCGTCCTGCGCTGCGGGCTCAGGCGGAACCCG GAACGGCCGTCCTCTTCCCCCGCCCTCCGCCGCCTCCTCCTTCTCCTCCTCCTCCTCCTCCTCCTCCTTCTCGGCTTCCTCCTCAGCCCC GGGCCGGAGCGGGGTGTCGGCGGCGGCCGGTTCGGGCGGCGACTCGCGCTTCTTTGGGCGGCGGCGCTTGGCCATGTCGTGTCGGGGAAG GTAATGAGCCGCAGAGCCCCGGGGTCTCGGCTGAGCAGCGGCGGCGGCGGCGGCGGCACCAAGTATCCGCGGAGCTGGAATGACTGGCAA CCCAGAACTGATAGTGCATCAGCCGACCCAGATAATTTAAAATATTCTTCATCCAGAGATAGAGGTGGTTCTTCCTCTTATGGACTGCAA CCTTCAAATTCAGCTGTGGTGTCTCGGCAAAGGCACGATGATACCAGAGTCCACGCTGACATACAGAATGACGAAAAGGGTGGCTACAGT GTCAATGGAGGATCTGGGGAAAATACTTATGGTCGGAAGTCGTTGGGGCAAGAGCTGAGGGTTAACAATGTGACCAGCCCTGAGTTCACC AGTGTTCAGCATGGCAGTCGTGCTTTAGCCACCAAAGACATGAGGAAATCACAGGAGAGATCGATGTCTTATTCTGATGAGTCTCGACTG TCGAATCTTCTTCGGAGGATCACCCGGGAAGACGACAGAGACCGAAGATTGGCTACTGTAAAGCAGTTGAAAGAATTTATTCAGCAACCA GAAAATAAGCTGGTACTAGTTAAACAATTGGATAATATCTTGGCTGCTGTACATGACGTGCTTAATGAAAGTAGCAAATTGCTTCAGGAG TTGAGACAGGAGGGAGCTTGCTGTCTTGGCCTTCTTTGTGCTTCTCTGAGCTATGAGGCTGAGAAGATCTTCAAGTGGATTTTTAGCAAA TTTAGCTCATCTGCAAAAGATGAAGTTAAACTCCTCTACTTATGTGCCACCTACAAAGCACTAGAGACTGTAGGAGAAAAGAAAGCCTTT TCATCTGTAATGCAGCTTGTAATGACCAGCCTGCAGTCTATTCTTGAAAATGTGGATACACCAGAATTGCTTTGTAAATGTGTTAAGTGC ATTCTTTTGGTGGCTCGATGTTACCCTCATATTTTCAGCACTAATTTTAGGGATACAGTTGATATATTAGTTGGATGGCATATAGATCAT ACTCAGAAACCTTCGCTCACGCAGCAGGTATCTGGGTGGTTGCAGAGTTTGGAGCCATTTTGGGTAGCTGATCTTGCATTTTCTACTACT CTTCTTGGTCAGTTTCTGGAAGACATGGAAGCATATGCTGAGGACCTCAGCCATGTGGCCTCTGGGGAATCAGTGGATGAAGATGTCCCT CCTCCATCAGTGTCATTACCAAAGCTGGCTGCACTTCTCCGGGTATTTAGTACTGTGGTGAGGAGCATTGGGGAACGCTTCAGCCCAATT CGGGGTCCTCCAATTACTGAGGCATATGTAACAGATGTTCTGTACAGAGTAATGAGATGTGTGACGGCTGCAAACCAGGTGTTTTTTTCT GAGGCTGTGTTGACAGCTGCTAATGAGTGTGTTGGTGTTTTGCTCGGCAGCTTGGATCCTAGCATGACTATACATTGTGACATGGTCATT ACATATGGATTAGACCAACTGGAGAATTGCCAGACTTGTGGTACCGATTATATCATCTCAGTCTTGAATTTACTCACGCTGATTGTTGAA CAGATAAATACGAAACTGCCATCATCATTTGTAGAAAAACTGTTTATACCATCATCTAAACTACTATTCTTGCGTTATCATAAAGAAAAA GAGGTTGTTGCTGTAGCCCATGCTGTTTATCAAGCAGTGCTCAGCTTGAAGAATATTCCTGTTTTGGAGACTGCCTATAAGTTAATATTG GGAGAAATGACTTGTGCCCTAAACAACCTCCTACACAGTCTACAACTTCCTGAGGCCTGTTCTGAAATAAAACATGAGGCTTTTAAGAAT CATGTGTTCAATGTAGACAATGCAAAATTTGTAGTTATATTTGACCTCAGTGCCCTGACTACAATTGGAAATGCCAAAAACTCACTAATA GGGATGTGGGCGCTATCTCCAACTGTCTTTGCACTTCTGAGTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCC ATTCAGTATGCTGTGCTCTACACATTGTATTCTCATTGTACCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCT TTGTTTGATGGAGCTGTGATTAGCACTGTAACTACGGCTACAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAG AAAGATAACCTTAACCAGGACACGAGGAAACTGTTAATGACTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCA CCTTTATTCTCTCTTCCGTCTTTCCATAAATTTTGCAAAGGCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCA TGCAGCAGTCTACATGCTCTGTCCTCTTCCTTGCCAGATGATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGT GGAACTCGTATTCGACAAGCATTTGGAAAACTGTTGAAATCAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAA GAAATTTCTTTAGCATTAAGAAGTCACATGAGTAAAGCACCAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATT TTGTATGGGAACTCTCATAGAACAGGGAAGGACAATTGGTTGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCA ACAATTCCACGCAATCTCCTGAAGACAGATGCTGTCCTTTGGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTG AGAACCCCACTGGGCAGAGCTCAAGACACCTTCCAGACAATTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAG GATGTTAGTCAGTGGACAACTGCAGACAATGATGAAGGCCATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAAT CTGGAGAAATTAATGTATAATGCATACGAGGGATGTGCTAATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAAT CGCCAAACTTGTCAGGACTGGCTAACGCGGATTCGACTCTCCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGA CATGGCTTTGACTTGCTTACAGAGATGAAAACAACCAGCCTATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCA TTATGTGAACTTCATTGTCCTGAAGCTATACAGGGAATTGCTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCA GTGGCTCAACAGGCTGAAGGGAGGTTTGAAAAGGCCTCTGTGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATC TCCAGCTTTGACAAATCGGTGCTCACCTTAGCCAATGCTGGGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAA ACTGTGCTGTCCAAACCGACTGACTCTTCCCCTGAGGTTATAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGAT TGGGCTGCTGTGCAGGAATGGCAGAACGCTATCCATGACTTGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAAC TATATAAAATCATTAAGCAGCTTTGAGTCTGGAAAATTTGTTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTA CTTGCTGGAGGATCAAAAGAAAAAATAGACATGAAAAAACTGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATT GAAGTTCAATTGTTAAGAAGTTCTGTTTGTTTGGCAACTGCTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAAT GTGGTAAAGTACTTGAAGCAAACATCCCGCATCGCTATTGGACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTA AGTACCTTGCAGCTGTATTGCTCATCTGCTTTGGAGAACACAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGT GAAGCTTTACGTTCATGTAAACAGCATGACGTGAGGCCATGGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAA ATTAAAGGTATCTGGCTTGGAATTCTCGAAGGAATCGGTATATTGGCTGTGATCACCAATGCATTTGTAATTGCTATTACTTCTGATTAC ATCCCACGTTTTGTTTATGAATACAAATATGGCCCCTGTGCAAATCATGTAGAACCAAGTGAAAATTGCTTGAAGGGATATGTCAACAAT AGCCTATCCTTCTTTGACCTGAGTGAGCTTGGTATGGGAAAATCTGGTTATTGCAGGTACAGAGACTACAGAGGCCCGCCCTGGAGTTCC AAACCCTATGAGTTTACTTTACAATACTGGCATATCCTTGCTGCTAGATTGGCCTTCATTATTGTGTTTGAGCACCTTGTTTTTGGGATT AAGTCATTCATCGCATACCTGATTCCAGACGTACCAAAGGGTCTACATGACCGAATACGACGAGAGAAGTACTTAGTTCAAGAAATGATG TATGAGGCTGAACTGGAACATTTGCAACAACAACGGAGAAAAAGTGGTCAGCCTGTTCACCATGAATGGCCTTAGTTGACACCTGTTACC CATTAGGGGTGATAACATTAATGGGAAGAAATGATGGCAACTTTGAATGCTAGGTGAAATCTAGGAGGAAGGCATACTTGGCAAACCACA TGTATAATATGCTACTTGGAAATGTATCACAGCCATCTCTGGGATTTGAAATATCCAGACTTGTAGGGAAGAAAACAATGACTTGACGAC >In-frame_ENST00000389467_ENST00000537978_TCGA-A2-A0EY-01A_SMG1_chr16_18869492_-_ANO3_chr11_26669256_length(amino acids)=1653AA_start in transcript=153_stop in transcript=5114 MRCGLRRNPERPSSSPALRRLLLLLLLLLLLLLGFLLSPGPERGVGGGRFGRRLALLWAAALGHVVSGKVMSRRAPGSRLSSGGGGGGTK YPRSWNDWQPRTDSASADPDNLKYSSSRDRGGSSSYGLQPSNSAVVSRQRHDDTRVHADIQNDEKGGYSVNGGSGENTYGRKSLGQELRV NNVTSPEFTSVQHGSRALATKDMRKSQERSMSYSDESRLSNLLRRITREDDRDRRLATVKQLKEFIQQPENKLVLVKQLDNILAAVHDVL NESSKLLQELRQEGACCLGLLCASLSYEAEKIFKWIFSKFSSSAKDEVKLLYLCATYKALETVGEKKAFSSVMQLVMTSLQSILENVDTP ELLCKCVKCILLVARCYPHIFSTNFRDTVDILVGWHIDHTQKPSLTQQVSGWLQSLEPFWVADLAFSTTLLGQFLEDMEAYAEDLSHVAS GESVDEDVPPPSVSLPKLAALLRVFSTVVRSIGERFSPIRGPPITEAYVTDVLYRVMRCVTAANQVFFSEAVLTAANECVGVLLGSLDPS MTIHCDMVITYGLDQLENCQTCGTDYIISVLNLLTLIVEQINTKLPSSFVEKLFIPSSKLLFLRYHKEKEVVAVAHAVYQAVLSLKNIPV LETAYKLILGEMTCALNNLLHSLQLPEACSEIKHEAFKNHVFNVDNAKFVVIFDLSALTTIGNAKNSLIGMWALSPTVFALLSKNLMIVH SDLAVHFPAIQYAVLYTLYSHCTRHDHFISSSLSSSSPSLFDGAVISTVTTATKKHFSIILNLLGILLKKDNLNQDTRKLLMTWALEAAV LMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNICLQACSSLHALSSSLPDDLLQRCVDVCRVQLVHSGTRIRQAFGKLLKSIPLDVVL SNNNHTEIQEISLALRSHMSKAPSNTFHPQDFSDVISFILYGNSHRTGKDNWLERLFYSCQRLDKRDQSTIPRNLLKTDAVLWQWAIWEA AQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTADNDEGHGNNQLRLVLLLQYLENLEKLMYNAYEGCANALTSPPK VIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLTEMKTTSLSQGNELEVTIMMVVEALCELHCPEAIQGIAVWSSSIV GKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVDCCISSFDKSVLTLANAGRNSASPKHSLNGESRKTVLSKPTDSSPEVINYLGNKA CECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLKADFNYIKSLSSFESGKFVECTEQLELLPGENINLLAGGSKEKIDMKKLLPNMLSP DPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQSITENVVKYLKQTSRIAIGPLRLSTLTVSQSLPVLSTLQLYCSSALENTVSNRLST EDCLIPLFSEALRSCKQHDVRPWMQALRYTMYQNQLLEKIKGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSE NCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRR -------------------------------------------------------------- >In-frame_ENST00000389467_ENST00000525139_TCGA-A2-A0EY-01A_SMG1_chr16_18869492_-_ANO3_chr11_26669256_length(transcript)=5351nt_BP=4597nt GCCGTGTGAGCGTGAGGAGCTGCCGCCACCGCCTGCTCCTCGTCGTCCTCGTCCTCCGGGGCCCCGGCGACGTGGGCCGCGCACGGCCCT GGAAAAGACGTCGCCTCCCCTTCATCCGCCTCTCTCTCACCGCGCCGCTCCCGCCTCCTCGTCCTGCGCTGCGGGCTCAGGCGGAACCCG GAACGGCCGTCCTCTTCCCCCGCCCTCCGCCGCCTCCTCCTTCTCCTCCTCCTCCTCCTCCTCCTCCTTCTCGGCTTCCTCCTCAGCCCC GGGCCGGAGCGGGGTGTCGGCGGCGGCCGGTTCGGGCGGCGACTCGCGCTTCTTTGGGCGGCGGCGCTTGGCCATGTCGTGTCGGGGAAG GTAATGAGCCGCAGAGCCCCGGGGTCTCGGCTGAGCAGCGGCGGCGGCGGCGGCGGCACCAAGTATCCGCGGAGCTGGAATGACTGGCAA CCCAGAACTGATAGTGCATCAGCCGACCCAGATAATTTAAAATATTCTTCATCCAGAGATAGAGGTGGTTCTTCCTCTTATGGACTGCAA CCTTCAAATTCAGCTGTGGTGTCTCGGCAAAGGCACGATGATACCAGAGTCCACGCTGACATACAGAATGACGAAAAGGGTGGCTACAGT GTCAATGGAGGATCTGGGGAAAATACTTATGGTCGGAAGTCGTTGGGGCAAGAGCTGAGGGTTAACAATGTGACCAGCCCTGAGTTCACC AGTGTTCAGCATGGCAGTCGTGCTTTAGCCACCAAAGACATGAGGAAATCACAGGAGAGATCGATGTCTTATTCTGATGAGTCTCGACTG TCGAATCTTCTTCGGAGGATCACCCGGGAAGACGACAGAGACCGAAGATTGGCTACTGTAAAGCAGTTGAAAGAATTTATTCAGCAACCA GAAAATAAGCTGGTACTAGTTAAACAATTGGATAATATCTTGGCTGCTGTACATGACGTGCTTAATGAAAGTAGCAAATTGCTTCAGGAG TTGAGACAGGAGGGAGCTTGCTGTCTTGGCCTTCTTTGTGCTTCTCTGAGCTATGAGGCTGAGAAGATCTTCAAGTGGATTTTTAGCAAA TTTAGCTCATCTGCAAAAGATGAAGTTAAACTCCTCTACTTATGTGCCACCTACAAAGCACTAGAGACTGTAGGAGAAAAGAAAGCCTTT TCATCTGTAATGCAGCTTGTAATGACCAGCCTGCAGTCTATTCTTGAAAATGTGGATACACCAGAATTGCTTTGTAAATGTGTTAAGTGC ATTCTTTTGGTGGCTCGATGTTACCCTCATATTTTCAGCACTAATTTTAGGGATACAGTTGATATATTAGTTGGATGGCATATAGATCAT ACTCAGAAACCTTCGCTCACGCAGCAGGTATCTGGGTGGTTGCAGAGTTTGGAGCCATTTTGGGTAGCTGATCTTGCATTTTCTACTACT CTTCTTGGTCAGTTTCTGGAAGACATGGAAGCATATGCTGAGGACCTCAGCCATGTGGCCTCTGGGGAATCAGTGGATGAAGATGTCCCT CCTCCATCAGTGTCATTACCAAAGCTGGCTGCACTTCTCCGGGTATTTAGTACTGTGGTGAGGAGCATTGGGGAACGCTTCAGCCCAATT CGGGGTCCTCCAATTACTGAGGCATATGTAACAGATGTTCTGTACAGAGTAATGAGATGTGTGACGGCTGCAAACCAGGTGTTTTTTTCT GAGGCTGTGTTGACAGCTGCTAATGAGTGTGTTGGTGTTTTGCTCGGCAGCTTGGATCCTAGCATGACTATACATTGTGACATGGTCATT ACATATGGATTAGACCAACTGGAGAATTGCCAGACTTGTGGTACCGATTATATCATCTCAGTCTTGAATTTACTCACGCTGATTGTTGAA CAGATAAATACGAAACTGCCATCATCATTTGTAGAAAAACTGTTTATACCATCATCTAAACTACTATTCTTGCGTTATCATAAAGAAAAA GAGGTTGTTGCTGTAGCCCATGCTGTTTATCAAGCAGTGCTCAGCTTGAAGAATATTCCTGTTTTGGAGACTGCCTATAAGTTAATATTG GGAGAAATGACTTGTGCCCTAAACAACCTCCTACACAGTCTACAACTTCCTGAGGCCTGTTCTGAAATAAAACATGAGGCTTTTAAGAAT CATGTGTTCAATGTAGACAATGCAAAATTTGTAGTTATATTTGACCTCAGTGCCCTGACTACAATTGGAAATGCCAAAAACTCACTAATA GGGATGTGGGCGCTATCTCCAACTGTCTTTGCACTTCTGAGTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCC ATTCAGTATGCTGTGCTCTACACATTGTATTCTCATTGTACCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCT TTGTTTGATGGAGCTGTGATTAGCACTGTAACTACGGCTACAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAG AAAGATAACCTTAACCAGGACACGAGGAAACTGTTAATGACTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCA CCTTTATTCTCTCTTCCGTCTTTCCATAAATTTTGCAAAGGCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCA TGCAGCAGTCTACATGCTCTGTCCTCTTCCTTGCCAGATGATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGT GGAACTCGTATTCGACAAGCATTTGGAAAACTGTTGAAATCAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAA GAAATTTCTTTAGCATTAAGAAGTCACATGAGTAAAGCACCAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATT TTGTATGGGAACTCTCATAGAACAGGGAAGGACAATTGGTTGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCA ACAATTCCACGCAATCTCCTGAAGACAGATGCTGTCCTTTGGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTG AGAACCCCACTGGGCAGAGCTCAAGACACCTTCCAGACAATTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAG GATGTTAGTCAGTGGACAACTGCAGACAATGATGAAGGCCATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAAT CTGGAGAAATTAATGTATAATGCATACGAGGGATGTGCTAATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAAT CGCCAAACTTGTCAGGACTGGCTAACGCGGATTCGACTCTCCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGA CATGGCTTTGACTTGCTTACAGAGATGAAAACAACCAGCCTATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCA TTATGTGAACTTCATTGTCCTGAAGCTATACAGGGAATTGCTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCA GTGGCTCAACAGGCTGAAGGGAGGTTTGAAAAGGCCTCTGTGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATC TCCAGCTTTGACAAATCGGTGCTCACCTTAGCCAATGCTGGGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAA ACTGTGCTGTCCAAACCGACTGACTCTTCCCCTGAGGTTATAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGAT TGGGCTGCTGTGCAGGAATGGCAGAACGCTATCCATGACTTGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAAC TATATAAAATCATTAAGCAGCTTTGAGTCTGGAAAATTTGTTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTA CTTGCTGGAGGATCAAAAGAAAAAATAGACATGAAAAAACTGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATT GAAGTTCAATTGTTAAGAAGTTCTGTTTGTTTGGCAACTGCTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAAT GTGGTAAAGTACTTGAAGCAAACATCCCGCATCGCTATTGGACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTA AGTACCTTGCAGCTGTATTGCTCATCTGCTTTGGAGAACACAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGT GAAGCTTTACGTTCATGTAAACAGCATGACGTGAGGCCATGGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAA ATTAAAGGTATCTGGCTTGGAATTCTCGAAGGAATCGGTATATTGGCTGTGATCACCAATGCATTTGTAATTGCTATTACTTCTGATTAC ATCCCACGTTTTGTTTATGAATACAAATATGGCCCCTGTGCAAATCATGTAGAACCAAGTGAAAATTGCTTGAAGGGATATGTCAACAAT AGCCTATCCTTCTTTGACCTGAGTGAGCTTGGTATGGGAAAATCTGGTTATTGCAGGTACAGAGACTACAGAGGCCCGCCCTGGAGTTCC AAACCCTATGAGTTTACTTTACAATACTGGCATATCCTTGCTGCTAGATTGGCCTTCATTATTGTGTTTGAGCACCTTGTTTTTGGGATT AAGTCATTCATCGCATACCTGATTCCAGACGTACCAAAGGGTCTACATGACCGAATACGACGAGAGAAGTACTTAGTTCAAGAAATGATG TATGAGGCTGAACTGGAACATTTGCAACAACAACGGAGAAAAAGTGGTCAGCCTGTTCACCATGAATGGCCTTAGTTGACACCTGTTACC CATTAGGGGTGATAACATTAATGGGAAGAAATGATGGCAACTTTGAATGCTAGGTGAAATCTAGGAGGAAGGCATACTTGGCAAACCACA TGTATAATATGCTACTTGGAAATGTATCACAGCCATCTCTGGGATTTGAAATATCCAGACTTGTAGGGAAGAAAACAATGACTTGACGAC >In-frame_ENST00000389467_ENST00000525139_TCGA-A2-A0EY-01A_SMG1_chr16_18869492_-_ANO3_chr11_26669256_length(amino acids)=1653AA_start in transcript=153_stop in transcript=5114 MRCGLRRNPERPSSSPALRRLLLLLLLLLLLLLGFLLSPGPERGVGGGRFGRRLALLWAAALGHVVSGKVMSRRAPGSRLSSGGGGGGTK YPRSWNDWQPRTDSASADPDNLKYSSSRDRGGSSSYGLQPSNSAVVSRQRHDDTRVHADIQNDEKGGYSVNGGSGENTYGRKSLGQELRV NNVTSPEFTSVQHGSRALATKDMRKSQERSMSYSDESRLSNLLRRITREDDRDRRLATVKQLKEFIQQPENKLVLVKQLDNILAAVHDVL NESSKLLQELRQEGACCLGLLCASLSYEAEKIFKWIFSKFSSSAKDEVKLLYLCATYKALETVGEKKAFSSVMQLVMTSLQSILENVDTP ELLCKCVKCILLVARCYPHIFSTNFRDTVDILVGWHIDHTQKPSLTQQVSGWLQSLEPFWVADLAFSTTLLGQFLEDMEAYAEDLSHVAS GESVDEDVPPPSVSLPKLAALLRVFSTVVRSIGERFSPIRGPPITEAYVTDVLYRVMRCVTAANQVFFSEAVLTAANECVGVLLGSLDPS MTIHCDMVITYGLDQLENCQTCGTDYIISVLNLLTLIVEQINTKLPSSFVEKLFIPSSKLLFLRYHKEKEVVAVAHAVYQAVLSLKNIPV LETAYKLILGEMTCALNNLLHSLQLPEACSEIKHEAFKNHVFNVDNAKFVVIFDLSALTTIGNAKNSLIGMWALSPTVFALLSKNLMIVH SDLAVHFPAIQYAVLYTLYSHCTRHDHFISSSLSSSSPSLFDGAVISTVTTATKKHFSIILNLLGILLKKDNLNQDTRKLLMTWALEAAV LMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNICLQACSSLHALSSSLPDDLLQRCVDVCRVQLVHSGTRIRQAFGKLLKSIPLDVVL SNNNHTEIQEISLALRSHMSKAPSNTFHPQDFSDVISFILYGNSHRTGKDNWLERLFYSCQRLDKRDQSTIPRNLLKTDAVLWQWAIWEA AQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTADNDEGHGNNQLRLVLLLQYLENLEKLMYNAYEGCANALTSPPK VIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLTEMKTTSLSQGNELEVTIMMVVEALCELHCPEAIQGIAVWSSSIV GKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVDCCISSFDKSVLTLANAGRNSASPKHSLNGESRKTVLSKPTDSSPEVINYLGNKA CECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLKADFNYIKSLSSFESGKFVECTEQLELLPGENINLLAGGSKEKIDMKKLLPNMLSP DPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQSITENVVKYLKQTSRIAIGPLRLSTLTVSQSLPVLSTLQLYCSSALENTVSNRLST EDCLIPLFSEALRSCKQHDVRPWMQALRYTMYQNQLLEKIKGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSE NCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRR -------------------------------------------------------------- >In-frame_ENST00000389467_ENST00000256737_TCGA-A2-A0EY-01A_SMG1_chr16_18869492_-_ANO3_chr11_26669256_length(transcript)=7959nt_BP=4597nt GCCGTGTGAGCGTGAGGAGCTGCCGCCACCGCCTGCTCCTCGTCGTCCTCGTCCTCCGGGGCCCCGGCGACGTGGGCCGCGCACGGCCCT GGAAAAGACGTCGCCTCCCCTTCATCCGCCTCTCTCTCACCGCGCCGCTCCCGCCTCCTCGTCCTGCGCTGCGGGCTCAGGCGGAACCCG GAACGGCCGTCCTCTTCCCCCGCCCTCCGCCGCCTCCTCCTTCTCCTCCTCCTCCTCCTCCTCCTCCTTCTCGGCTTCCTCCTCAGCCCC GGGCCGGAGCGGGGTGTCGGCGGCGGCCGGTTCGGGCGGCGACTCGCGCTTCTTTGGGCGGCGGCGCTTGGCCATGTCGTGTCGGGGAAG GTAATGAGCCGCAGAGCCCCGGGGTCTCGGCTGAGCAGCGGCGGCGGCGGCGGCGGCACCAAGTATCCGCGGAGCTGGAATGACTGGCAA CCCAGAACTGATAGTGCATCAGCCGACCCAGATAATTTAAAATATTCTTCATCCAGAGATAGAGGTGGTTCTTCCTCTTATGGACTGCAA CCTTCAAATTCAGCTGTGGTGTCTCGGCAAAGGCACGATGATACCAGAGTCCACGCTGACATACAGAATGACGAAAAGGGTGGCTACAGT GTCAATGGAGGATCTGGGGAAAATACTTATGGTCGGAAGTCGTTGGGGCAAGAGCTGAGGGTTAACAATGTGACCAGCCCTGAGTTCACC AGTGTTCAGCATGGCAGTCGTGCTTTAGCCACCAAAGACATGAGGAAATCACAGGAGAGATCGATGTCTTATTCTGATGAGTCTCGACTG TCGAATCTTCTTCGGAGGATCACCCGGGAAGACGACAGAGACCGAAGATTGGCTACTGTAAAGCAGTTGAAAGAATTTATTCAGCAACCA GAAAATAAGCTGGTACTAGTTAAACAATTGGATAATATCTTGGCTGCTGTACATGACGTGCTTAATGAAAGTAGCAAATTGCTTCAGGAG TTGAGACAGGAGGGAGCTTGCTGTCTTGGCCTTCTTTGTGCTTCTCTGAGCTATGAGGCTGAGAAGATCTTCAAGTGGATTTTTAGCAAA TTTAGCTCATCTGCAAAAGATGAAGTTAAACTCCTCTACTTATGTGCCACCTACAAAGCACTAGAGACTGTAGGAGAAAAGAAAGCCTTT TCATCTGTAATGCAGCTTGTAATGACCAGCCTGCAGTCTATTCTTGAAAATGTGGATACACCAGAATTGCTTTGTAAATGTGTTAAGTGC ATTCTTTTGGTGGCTCGATGTTACCCTCATATTTTCAGCACTAATTTTAGGGATACAGTTGATATATTAGTTGGATGGCATATAGATCAT ACTCAGAAACCTTCGCTCACGCAGCAGGTATCTGGGTGGTTGCAGAGTTTGGAGCCATTTTGGGTAGCTGATCTTGCATTTTCTACTACT CTTCTTGGTCAGTTTCTGGAAGACATGGAAGCATATGCTGAGGACCTCAGCCATGTGGCCTCTGGGGAATCAGTGGATGAAGATGTCCCT CCTCCATCAGTGTCATTACCAAAGCTGGCTGCACTTCTCCGGGTATTTAGTACTGTGGTGAGGAGCATTGGGGAACGCTTCAGCCCAATT CGGGGTCCTCCAATTACTGAGGCATATGTAACAGATGTTCTGTACAGAGTAATGAGATGTGTGACGGCTGCAAACCAGGTGTTTTTTTCT GAGGCTGTGTTGACAGCTGCTAATGAGTGTGTTGGTGTTTTGCTCGGCAGCTTGGATCCTAGCATGACTATACATTGTGACATGGTCATT ACATATGGATTAGACCAACTGGAGAATTGCCAGACTTGTGGTACCGATTATATCATCTCAGTCTTGAATTTACTCACGCTGATTGTTGAA CAGATAAATACGAAACTGCCATCATCATTTGTAGAAAAACTGTTTATACCATCATCTAAACTACTATTCTTGCGTTATCATAAAGAAAAA GAGGTTGTTGCTGTAGCCCATGCTGTTTATCAAGCAGTGCTCAGCTTGAAGAATATTCCTGTTTTGGAGACTGCCTATAAGTTAATATTG GGAGAAATGACTTGTGCCCTAAACAACCTCCTACACAGTCTACAACTTCCTGAGGCCTGTTCTGAAATAAAACATGAGGCTTTTAAGAAT CATGTGTTCAATGTAGACAATGCAAAATTTGTAGTTATATTTGACCTCAGTGCCCTGACTACAATTGGAAATGCCAAAAACTCACTAATA GGGATGTGGGCGCTATCTCCAACTGTCTTTGCACTTCTGAGTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCC ATTCAGTATGCTGTGCTCTACACATTGTATTCTCATTGTACCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCT TTGTTTGATGGAGCTGTGATTAGCACTGTAACTACGGCTACAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAG AAAGATAACCTTAACCAGGACACGAGGAAACTGTTAATGACTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCA CCTTTATTCTCTCTTCCGTCTTTCCATAAATTTTGCAAAGGCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCA TGCAGCAGTCTACATGCTCTGTCCTCTTCCTTGCCAGATGATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGT GGAACTCGTATTCGACAAGCATTTGGAAAACTGTTGAAATCAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAA GAAATTTCTTTAGCATTAAGAAGTCACATGAGTAAAGCACCAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATT TTGTATGGGAACTCTCATAGAACAGGGAAGGACAATTGGTTGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCA ACAATTCCACGCAATCTCCTGAAGACAGATGCTGTCCTTTGGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTG AGAACCCCACTGGGCAGAGCTCAAGACACCTTCCAGACAATTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAG GATGTTAGTCAGTGGACAACTGCAGACAATGATGAAGGCCATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAAT CTGGAGAAATTAATGTATAATGCATACGAGGGATGTGCTAATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAAT CGCCAAACTTGTCAGGACTGGCTAACGCGGATTCGACTCTCCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGA CATGGCTTTGACTTGCTTACAGAGATGAAAACAACCAGCCTATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCA TTATGTGAACTTCATTGTCCTGAAGCTATACAGGGAATTGCTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCA GTGGCTCAACAGGCTGAAGGGAGGTTTGAAAAGGCCTCTGTGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATC TCCAGCTTTGACAAATCGGTGCTCACCTTAGCCAATGCTGGGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAA ACTGTGCTGTCCAAACCGACTGACTCTTCCCCTGAGGTTATAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGAT TGGGCTGCTGTGCAGGAATGGCAGAACGCTATCCATGACTTGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAAC TATATAAAATCATTAAGCAGCTTTGAGTCTGGAAAATTTGTTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTA CTTGCTGGAGGATCAAAAGAAAAAATAGACATGAAAAAACTGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATT GAAGTTCAATTGTTAAGAAGTTCTGTTTGTTTGGCAACTGCTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAAT GTGGTAAAGTACTTGAAGCAAACATCCCGCATCGCTATTGGACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTA AGTACCTTGCAGCTGTATTGCTCATCTGCTTTGGAGAACACAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGT GAAGCTTTACGTTCATGTAAACAGCATGACGTGAGGCCATGGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAA ATTAAAGGTATCTGGCTTGGAATTCTCGAAGGAATCGGTATATTGGCTGTGATCACCAATGCATTTGTAATTGCTATTACTTCTGATTAC ATCCCACGTTTTGTTTATGAATACAAATATGGCCCCTGTGCAAATCATGTAGAACCAAGTGAAAATTGCTTGAAGGGATATGTCAACAAT AGCCTATCCTTCTTTGACCTGAGTGAGCTTGGTATGGGAAAATCTGGTTATTGCAGGTACAGAGACTACAGAGGCCCGCCCTGGAGTTCC AAACCCTATGAGTTTACTTTACAATACTGGCATATCCTTGCTGCTAGATTGGCCTTCATTATTGTGTTTGAGCACCTTGTTTTTGGGATT AAGTCATTCATCGCATACCTGATTCCAGACGTACCAAAGGGTCTACATGACCGAATACGACGAGAGAAGTACTTAGTTCAAGAAATGATG TATGAGGCTGAACTGGAACATTTGCAACAACAACGGAGAAAAAGTGGTCAGCCTGTTCACCATGAATGGCCTTAGTTGACACCTGTTACC CATTAGGGGTGATAACATTAATGGGAAGAAATGATGGCAACTTTGAATGCTAGGTGAAATCTAGGAGGAAGGCATACTTGGCAAACCACA TGTATAATATGCTACTTGGAAATGTATCACAGCCATCTCTGGGATTTGAAATATCCAGACTTGTAGGGAAGAAAACAATGACTTGACGAC CTTAAAAAGGGTTAGATTGACATTGCAGGAAGCCAGGATGTAATTCTCAGAACCAGTCTCAGGGAGATATATGCTTGGAGAACTCTGCCT TCCATCAACTGCAGTGTAATGGGAAAGAGGGTGGTGAGGTTTTGAAAGACAGATTTCCATGTAAATGTGCACAAGCCAGGCATGGCTTAA AATATCATGCAGTCTTCACTCACATACTAATTTGACTTTGGAAAGTATGGTTGAGTTCAGATACTTATAAGAAATGACTTAAACAAATCC TTGCCTTGGCTGCCAGAACTCTACATCCCTTCAGTTTACAGGTTGGTAGGAATTGCCCATGTCTCTTGCTGAGATTATGGATCTGTGCCA CAGGGGATTTATGCTGCTTTACATTGACTATGCAGTTGAAGAGTTGCACATCACCTTTAGTAGTCAAACCAAAAATCTAAGATTCCAAAA AGAACAGCATTCATTGAAATAATATTCCATTGCATTGGCTACTTCAAGTCTCTTTTACCCCTGGCAGAGCCAGTTGCAGTGCAATTTTTT GTACTAAATGCCAATAAAGCCACATACTTATAAACTATGAATGGCTATTCTTATATAGTTTAGAACACAACTAATCCATACTTTATTGTG GAAGGCTGTTTTATAGTTTATTTAATTTTTTCTCTATGATTTATTACAACTCTCACGGAATATTAACTTGAAATGCTGTAAATACGTTGG TTTTCCTTGTCCCTTTGCACCTTGACAGTACGTAGTATACATTGTGGTTTATGCAGCTCTGACACCAGTTTTTGCTATTGTAATATGTTT ATTCGGGAAAACTGAGGCCAGATGCTCTGCAACACTTACGCTTTTTCAACAATGTGCACTCTTACTCATGAACTAATGAAAATAATGCAT GAATATAAATCTATATTATTTGCTAAAAAAAGAAAAAACATTTGTGTTTTAGTTTCTTTTTTCATGACTGAAGGGAGTTTTATGTTATTA TTTCTTCCATAGTTTTGTTTTGGTTTATTTTTAACAACGCTCTAGAAACAAAGTCAAATTAATCACAAAAGACATAATTTTGCTTTGTTG TGGAATTTCTATTTCAACGTCAACTCTGTATCTATGAGTATGTCTGTTCCACAGACAGATGAGGCAGGAGTGATGGGGCACTCAAGAAAG TTCAGAGGAGGCATAAGCTATGGAGGTTGGAAAGGAAGAAAGAGAAGAGCTGAAGTAAATGTATGGTAGAAATTAAGACGTTTCTTTGCA AAACAAGGAAATCACACATATGCACACATACATATTTATGGTTACTATGATTGTTATTATTTGTCCAATCAAGCAAAGCACCATTATTTC TAACATATAAAAGACCAGATCAAACACAATGGAAATAAAGCTACTACATATATATGCCAGTATTTCTCTAGTAAGATTATGTTTCTCTTA CTAGAAAACTATTTTCTAAATATTAACACTGAAAATGTTTTGTTAGCTTTTCCTTCTTTCTCTCCAGAAGAAACATGGATAGATGATAGC TGTTTCATTGTTTGTTTTTGTCAAGCATATTCACTTTCCTCCTTGTCCTCTGATTCTGAGCAAAGGGCCTCAGACTCTGAACTTCCCTCA AGTGCCGTTGTTATGTGAAACTCTTCCATTCAGATTCCAGAGAGGTTCTCATGCTCCCCCCCCTCCTTATTTGTAGCAATCGTAGCAACT AATTCCACTAAGTACAAGGGAGTTTTTTACACTCCTCCATTTTTATAGCATCTGCATTTCTTTTTCTTTGTTAGGTACATGTATACACCT GCCTGAGTATAAATACTCTCTCTACCTAATAATAACATCAACCAACATCTTTTCCAAATTAGGGCCACAGAACAGCAACATTTGTCTGAC AGTAGTATAAAGAATAATGATAGCTCTATCCTTAAGAAGTATTTCCTTTCCTTTTTATATAGTCCCGTTAGGGTTTAAAACCATATTGAT CAACTAGAAAGAAAAATATGAAAAGAGAAAAATATTTTAATTTAAAAATTGTAATACATTGATTTATAAAATGCCTTCTCTGATACTTTT GAAACAGATGTGAAAAACAGAAAAAGAAAAAATTGTCTGAAATGTTTATTTTGCAAAACAGTGCAATAGAATCTAGTTATGCCTTCATCA CTGTTGACAGTAAATACTGACAGCCCCTTGCAGTGTGTTAGTTTTAGATCACTCTGTTTTAGTTGAGAGAAATGTTTTATATCATGGTTT TTATATGAATACAAATTATTTCTCAAAGATTTATAGCACACACTATTCTCAGGAATTCTGTATTACATGAATGCTGCTTATATATTTTCA TATTCTAACTTGTCTTTTCAAGCAAATAACTAATATATATGTGCATGCAGTCTGCCTTGACAAGTTGTTCCAAGCTGAAGAGCTTTCACT GTACAATGTGTGGAAAATCACCATAGATCATGGCTGAAATAGTTTGTAATTGTCTGAGTCTGTGCACGTACTTTTAGATAAAATGCTGCT GAGTGACTGCATGATGAGATACAACTTCTGAATGCTGCACATTCTTCCAAAATGATCCTTAGCACAATCTATTGTATGATGGAATGAATA >In-frame_ENST00000389467_ENST00000256737_TCGA-A2-A0EY-01A_SMG1_chr16_18869492_-_ANO3_chr11_26669256_length(amino acids)=1653AA_start in transcript=153_stop in transcript=5114 MRCGLRRNPERPSSSPALRRLLLLLLLLLLLLLGFLLSPGPERGVGGGRFGRRLALLWAAALGHVVSGKVMSRRAPGSRLSSGGGGGGTK YPRSWNDWQPRTDSASADPDNLKYSSSRDRGGSSSYGLQPSNSAVVSRQRHDDTRVHADIQNDEKGGYSVNGGSGENTYGRKSLGQELRV NNVTSPEFTSVQHGSRALATKDMRKSQERSMSYSDESRLSNLLRRITREDDRDRRLATVKQLKEFIQQPENKLVLVKQLDNILAAVHDVL NESSKLLQELRQEGACCLGLLCASLSYEAEKIFKWIFSKFSSSAKDEVKLLYLCATYKALETVGEKKAFSSVMQLVMTSLQSILENVDTP ELLCKCVKCILLVARCYPHIFSTNFRDTVDILVGWHIDHTQKPSLTQQVSGWLQSLEPFWVADLAFSTTLLGQFLEDMEAYAEDLSHVAS GESVDEDVPPPSVSLPKLAALLRVFSTVVRSIGERFSPIRGPPITEAYVTDVLYRVMRCVTAANQVFFSEAVLTAANECVGVLLGSLDPS MTIHCDMVITYGLDQLENCQTCGTDYIISVLNLLTLIVEQINTKLPSSFVEKLFIPSSKLLFLRYHKEKEVVAVAHAVYQAVLSLKNIPV LETAYKLILGEMTCALNNLLHSLQLPEACSEIKHEAFKNHVFNVDNAKFVVIFDLSALTTIGNAKNSLIGMWALSPTVFALLSKNLMIVH SDLAVHFPAIQYAVLYTLYSHCTRHDHFISSSLSSSSPSLFDGAVISTVTTATKKHFSIILNLLGILLKKDNLNQDTRKLLMTWALEAAV LMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNICLQACSSLHALSSSLPDDLLQRCVDVCRVQLVHSGTRIRQAFGKLLKSIPLDVVL SNNNHTEIQEISLALRSHMSKAPSNTFHPQDFSDVISFILYGNSHRTGKDNWLERLFYSCQRLDKRDQSTIPRNLLKTDAVLWQWAIWEA AQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTADNDEGHGNNQLRLVLLLQYLENLEKLMYNAYEGCANALTSPPK VIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLTEMKTTSLSQGNELEVTIMMVVEALCELHCPEAIQGIAVWSSSIV GKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVDCCISSFDKSVLTLANAGRNSASPKHSLNGESRKTVLSKPTDSSPEVINYLGNKA CECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLKADFNYIKSLSSFESGKFVECTEQLELLPGENINLLAGGSKEKIDMKKLLPNMLSP DPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQSITENVVKYLKQTSRIAIGPLRLSTLTVSQSLPVLSTLQLYCSSALENTVSNRLST EDCLIPLFSEALRSCKQHDVRPWMQALRYTMYQNQLLEKIKGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSE NCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRR -------------------------------------------------------------- >In-frame_ENST00000446231_ENST00000537978_TCGA-A2-A0EY-01A_SMG1_chr16_18869492_-_ANO3_chr11_26669256_length(transcript)=5401nt_BP=4647nt GTGCGACAGCGGCGGCGCGGCGGGCGGAGCCGGGAGGCGGGGAAGCAGTGGCCGTGTGAGCGTGAGGAGCTGCCGCCACCGCCTGCTCCT CGTCGTCCTCGTCCTCCGGGGCCCCGGCGACGTGGGCCGCGCACGGCCCTGGAAAAGACGTCGCCTCCCCTTCATCCGCCTCTCTCTCAC CGCGCCGCTCCCGCCTCCTCGTCCTGCGCTGCGGGCTCAGGCGGAACCCGGAACGGCCGTCCTCTTCCCCCGCCCTCCGCCGCCTCCTCC TTCTCCTCCTCCTCCTCCTCCTCCTCCTTCTCGGCTTCCTCCTCAGCCCCGGGCCGGAGCGGGGTGTCGGCGGCGGCCGGTTCGGGCGGC GACTCGCGCTTCTTTGGGCGGCGGCGCTTGGCCATGTCGTGTCGGGGAAGGTAATGAGCCGCAGAGCCCCGGGGTCTCGGCTGAGCAGCG GCGGCGGCGGCGGCGGCACCAAGTATCCGCGGAGCTGGAATGACTGGCAACCCAGAACTGATAGTGCATCAGCCGACCCAGATAATTTAA AATATTCTTCATCCAGAGATAGAGGTGGTTCTTCCTCTTATGGACTGCAACCTTCAAATTCAGCTGTGGTGTCTCGGCAAAGGCACGATG ATACCAGAGTCCACGCTGACATACAGAATGACGAAAAGGGTGGCTACAGTGTCAATGGAGGATCTGGGGAAAATACTTATGGTCGGAAGT CGTTGGGGCAAGAGCTGAGGGTTAACAATGTGACCAGCCCTGAGTTCACCAGTGTTCAGCATGGCAGTCGTGCTTTAGCCACCAAAGACA TGAGGAAATCACAGGAGAGATCGATGTCTTATTCTGATGAGTCTCGACTGTCGAATCTTCTTCGGAGGATCACCCGGGAAGACGACAGAG ACCGAAGATTGGCTACTGTAAAGCAGTTGAAAGAATTTATTCAGCAACCAGAAAATAAGCTGGTACTAGTTAAACAATTGGATAATATCT TGGCTGCTGTACATGACGTGCTTAATGAAAGTAGCAAATTGCTTCAGGAGTTGAGACAGGAGGGAGCTTGCTGTCTTGGCCTTCTTTGTG CTTCTCTGAGCTATGAGGCTGAGAAGATCTTCAAGTGGATTTTTAGCAAATTTAGCTCATCTGCAAAAGATGAAGTTAAACTCCTCTACT TATGTGCCACCTACAAAGCACTAGAGACTGTAGGAGAAAAGAAAGCCTTTTCATCTGTAATGCAGCTTGTAATGACCAGCCTGCAGTCTA TTCTTGAAAATGTGGATACACCAGAATTGCTTTGTAAATGTGTTAAGTGCATTCTTTTGGTGGCTCGATGTTACCCTCATATTTTCAGCA CTAATTTTAGGGATACAGTTGATATATTAGTTGGATGGCATATAGATCATACTCAGAAACCTTCGCTCACGCAGCAGGTATCTGGGTGGT TGCAGAGTTTGGAGCCATTTTGGGTAGCTGATCTTGCATTTTCTACTACTCTTCTTGGTCAGTTTCTGGAAGACATGGAAGCATATGCTG AGGACCTCAGCCATGTGGCCTCTGGGGAATCAGTGGATGAAGATGTCCCTCCTCCATCAGTGTCATTACCAAAGCTGGCTGCACTTCTCC GGGTATTTAGTACTGTGGTGAGGAGCATTGGGGAACGCTTCAGCCCAATTCGGGGTCCTCCAATTACTGAGGCATATGTAACAGATGTTC TGTACAGAGTAATGAGATGTGTGACGGCTGCAAACCAGGTGTTTTTTTCTGAGGCTGTGTTGACAGCTGCTAATGAGTGTGTTGGTGTTT TGCTCGGCAGCTTGGATCCTAGCATGACTATACATTGTGACATGGTCATTACATATGGATTAGACCAACTGGAGAATTGCCAGACTTGTG GTACCGATTATATCATCTCAGTCTTGAATTTACTCACGCTGATTGTTGAACAGATAAATACGAAACTGCCATCATCATTTGTAGAAAAAC TGTTTATACCATCATCTAAACTACTATTCTTGCGTTATCATAAAGAAAAAGAGGTTGTTGCTGTAGCCCATGCTGTTTATCAAGCAGTGC TCAGCTTGAAGAATATTCCTGTTTTGGAGACTGCCTATAAGTTAATATTGGGAGAAATGACTTGTGCCCTAAACAACCTCCTACACAGTC TACAACTTCCTGAGGCCTGTTCTGAAATAAAACATGAGGCTTTTAAGAATCATGTGTTCAATGTAGACAATGCAAAATTTGTAGTTATAT TTGACCTCAGTGCCCTGACTACAATTGGAAATGCCAAAAACTCACTAATAGGGATGTGGGCGCTATCTCCAACTGTCTTTGCACTTCTGA GTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCCATTCAGTATGCTGTGCTCTACACATTGTATTCTCATTGTA CCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCTTTGTTTGATGGAGCTGTGATTAGCACTGTAACTACGGCTA CAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAGAAAGATAACCTTAACCAGGACACGAGGAAACTGTTAATGA CTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCACCTTTATTCTCTCTTCCGTCTTTCCATAAATTTTGCAAAG GCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCATGCAGCAGTCTACATGCTCTGTCCTCTTCCTTGCCAGATG ATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGTGGAACTCGTATTCGACAAGCATTTGGAAAACTGTTGAAAT CAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAAGAAATTTCTTTAGCATTAAGAAGTCACATGAGTAAAGCAC CAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATTTTGTATGGGAACTCTCATAGAACAGGGAAGGACAATTGGT TGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCAACAATTCCACGCAATCTCCTGAAGACAGATGCTGTCCTTT GGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTGAGAACCCCACTGGGCAGAGCTCAAGACACCTTCCAGACAA TTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAGGATGTTAGTCAGTGGACAACTGCAGACAATGATGAAGGCC ATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAATCTGGAGAAATTAATGTATAATGCATACGAGGGATGTGCTA ATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAATCGCCAAACTTGTCAGGACTGGCTAACGCGGATTCGACTCT CCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGACATGGCTTTGACTTGCTTACAGAGATGAAAACAACCAGCC TATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCATTATGTGAACTTCATTGTCCTGAAGCTATACAGGGAATTG CTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCAGTGGCTCAACAGGCTGAAGGGAGGTTTGAAAAGGCCTCTG TGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATCTCCAGCTTTGACAAATCGGTGCTCACCTTAGCCAATGCTG GGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAAACTGTGCTGTCCAAACCGACTGACTCTTCCCCTGAGGTTA TAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGATTGGGCTGCTGTGCAGGAATGGCAGAACGCTATCCATGACT TGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAACTATATAAAATCATTAAGCAGCTTTGAGTCTGGAAAATTTG TTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTACTTGCTGGAGGATCAAAAGAAAAAATAGACATGAAAAAAC TGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATTGAAGTTCAATTGTTAAGAAGTTCTGTTTGTTTGGCAACTG CTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAATGTGGTAAAGTACTTGAAGCAAACATCCCGCATCGCTATTG GACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTAAGTACCTTGCAGCTGTATTGCTCATCTGCTTTGGAGAACA CAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGTGAAGCTTTACGTTCATGTAAACAGCATGACGTGAGGCCAT GGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAAATTAAAGGTATCTGGCTTGGAATTCTCGAAGGAATCGGTA TATTGGCTGTGATCACCAATGCATTTGTAATTGCTATTACTTCTGATTACATCCCACGTTTTGTTTATGAATACAAATATGGCCCCTGTG CAAATCATGTAGAACCAAGTGAAAATTGCTTGAAGGGATATGTCAACAATAGCCTATCCTTCTTTGACCTGAGTGAGCTTGGTATGGGAA AATCTGGTTATTGCAGGTACAGAGACTACAGAGGCCCGCCCTGGAGTTCCAAACCCTATGAGTTTACTTTACAATACTGGCATATCCTTG CTGCTAGATTGGCCTTCATTATTGTGTTTGAGCACCTTGTTTTTGGGATTAAGTCATTCATCGCATACCTGATTCCAGACGTACCAAAGG GTCTACATGACCGAATACGACGAGAGAAGTACTTAGTTCAAGAAATGATGTATGAGGCTGAACTGGAACATTTGCAACAACAACGGAGAA AAAGTGGTCAGCCTGTTCACCATGAATGGCCTTAGTTGACACCTGTTACCCATTAGGGGTGATAACATTAATGGGAAGAAATGATGGCAA CTTTGAATGCTAGGTGAAATCTAGGAGGAAGGCATACTTGGCAAACCACATGTATAATATGCTACTTGGAAATGTATCACAGCCATCTCT GGGATTTGAAATATCCAGACTTGTAGGGAAGAAAACAATGACTTGACGACCTTAAAAAGGGTTAGATTGACATTGCAGGAAGCCAGGATG >In-frame_ENST00000446231_ENST00000537978_TCGA-A2-A0EY-01A_SMG1_chr16_18869492_-_ANO3_chr11_26669256_length(amino acids)=1653AA_start in transcript=203_stop in transcript=5164 MRCGLRRNPERPSSSPALRRLLLLLLLLLLLLLGFLLSPGPERGVGGGRFGRRLALLWAAALGHVVSGKVMSRRAPGSRLSSGGGGGGTK YPRSWNDWQPRTDSASADPDNLKYSSSRDRGGSSSYGLQPSNSAVVSRQRHDDTRVHADIQNDEKGGYSVNGGSGENTYGRKSLGQELRV NNVTSPEFTSVQHGSRALATKDMRKSQERSMSYSDESRLSNLLRRITREDDRDRRLATVKQLKEFIQQPENKLVLVKQLDNILAAVHDVL NESSKLLQELRQEGACCLGLLCASLSYEAEKIFKWIFSKFSSSAKDEVKLLYLCATYKALETVGEKKAFSSVMQLVMTSLQSILENVDTP ELLCKCVKCILLVARCYPHIFSTNFRDTVDILVGWHIDHTQKPSLTQQVSGWLQSLEPFWVADLAFSTTLLGQFLEDMEAYAEDLSHVAS GESVDEDVPPPSVSLPKLAALLRVFSTVVRSIGERFSPIRGPPITEAYVTDVLYRVMRCVTAANQVFFSEAVLTAANECVGVLLGSLDPS MTIHCDMVITYGLDQLENCQTCGTDYIISVLNLLTLIVEQINTKLPSSFVEKLFIPSSKLLFLRYHKEKEVVAVAHAVYQAVLSLKNIPV LETAYKLILGEMTCALNNLLHSLQLPEACSEIKHEAFKNHVFNVDNAKFVVIFDLSALTTIGNAKNSLIGMWALSPTVFALLSKNLMIVH SDLAVHFPAIQYAVLYTLYSHCTRHDHFISSSLSSSSPSLFDGAVISTVTTATKKHFSIILNLLGILLKKDNLNQDTRKLLMTWALEAAV LMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNICLQACSSLHALSSSLPDDLLQRCVDVCRVQLVHSGTRIRQAFGKLLKSIPLDVVL SNNNHTEIQEISLALRSHMSKAPSNTFHPQDFSDVISFILYGNSHRTGKDNWLERLFYSCQRLDKRDQSTIPRNLLKTDAVLWQWAIWEA AQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTADNDEGHGNNQLRLVLLLQYLENLEKLMYNAYEGCANALTSPPK VIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLTEMKTTSLSQGNELEVTIMMVVEALCELHCPEAIQGIAVWSSSIV GKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVDCCISSFDKSVLTLANAGRNSASPKHSLNGESRKTVLSKPTDSSPEVINYLGNKA CECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLKADFNYIKSLSSFESGKFVECTEQLELLPGENINLLAGGSKEKIDMKKLLPNMLSP DPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQSITENVVKYLKQTSRIAIGPLRLSTLTVSQSLPVLSTLQLYCSSALENTVSNRLST EDCLIPLFSEALRSCKQHDVRPWMQALRYTMYQNQLLEKIKGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSE NCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRR -------------------------------------------------------------- >In-frame_ENST00000446231_ENST00000525139_TCGA-A2-A0EY-01A_SMG1_chr16_18869492_-_ANO3_chr11_26669256_length(transcript)=5401nt_BP=4647nt GTGCGACAGCGGCGGCGCGGCGGGCGGAGCCGGGAGGCGGGGAAGCAGTGGCCGTGTGAGCGTGAGGAGCTGCCGCCACCGCCTGCTCCT CGTCGTCCTCGTCCTCCGGGGCCCCGGCGACGTGGGCCGCGCACGGCCCTGGAAAAGACGTCGCCTCCCCTTCATCCGCCTCTCTCTCAC CGCGCCGCTCCCGCCTCCTCGTCCTGCGCTGCGGGCTCAGGCGGAACCCGGAACGGCCGTCCTCTTCCCCCGCCCTCCGCCGCCTCCTCC TTCTCCTCCTCCTCCTCCTCCTCCTCCTTCTCGGCTTCCTCCTCAGCCCCGGGCCGGAGCGGGGTGTCGGCGGCGGCCGGTTCGGGCGGC GACTCGCGCTTCTTTGGGCGGCGGCGCTTGGCCATGTCGTGTCGGGGAAGGTAATGAGCCGCAGAGCCCCGGGGTCTCGGCTGAGCAGCG GCGGCGGCGGCGGCGGCACCAAGTATCCGCGGAGCTGGAATGACTGGCAACCCAGAACTGATAGTGCATCAGCCGACCCAGATAATTTAA AATATTCTTCATCCAGAGATAGAGGTGGTTCTTCCTCTTATGGACTGCAACCTTCAAATTCAGCTGTGGTGTCTCGGCAAAGGCACGATG ATACCAGAGTCCACGCTGACATACAGAATGACGAAAAGGGTGGCTACAGTGTCAATGGAGGATCTGGGGAAAATACTTATGGTCGGAAGT CGTTGGGGCAAGAGCTGAGGGTTAACAATGTGACCAGCCCTGAGTTCACCAGTGTTCAGCATGGCAGTCGTGCTTTAGCCACCAAAGACA TGAGGAAATCACAGGAGAGATCGATGTCTTATTCTGATGAGTCTCGACTGTCGAATCTTCTTCGGAGGATCACCCGGGAAGACGACAGAG ACCGAAGATTGGCTACTGTAAAGCAGTTGAAAGAATTTATTCAGCAACCAGAAAATAAGCTGGTACTAGTTAAACAATTGGATAATATCT TGGCTGCTGTACATGACGTGCTTAATGAAAGTAGCAAATTGCTTCAGGAGTTGAGACAGGAGGGAGCTTGCTGTCTTGGCCTTCTTTGTG CTTCTCTGAGCTATGAGGCTGAGAAGATCTTCAAGTGGATTTTTAGCAAATTTAGCTCATCTGCAAAAGATGAAGTTAAACTCCTCTACT TATGTGCCACCTACAAAGCACTAGAGACTGTAGGAGAAAAGAAAGCCTTTTCATCTGTAATGCAGCTTGTAATGACCAGCCTGCAGTCTA TTCTTGAAAATGTGGATACACCAGAATTGCTTTGTAAATGTGTTAAGTGCATTCTTTTGGTGGCTCGATGTTACCCTCATATTTTCAGCA CTAATTTTAGGGATACAGTTGATATATTAGTTGGATGGCATATAGATCATACTCAGAAACCTTCGCTCACGCAGCAGGTATCTGGGTGGT TGCAGAGTTTGGAGCCATTTTGGGTAGCTGATCTTGCATTTTCTACTACTCTTCTTGGTCAGTTTCTGGAAGACATGGAAGCATATGCTG AGGACCTCAGCCATGTGGCCTCTGGGGAATCAGTGGATGAAGATGTCCCTCCTCCATCAGTGTCATTACCAAAGCTGGCTGCACTTCTCC GGGTATTTAGTACTGTGGTGAGGAGCATTGGGGAACGCTTCAGCCCAATTCGGGGTCCTCCAATTACTGAGGCATATGTAACAGATGTTC TGTACAGAGTAATGAGATGTGTGACGGCTGCAAACCAGGTGTTTTTTTCTGAGGCTGTGTTGACAGCTGCTAATGAGTGTGTTGGTGTTT TGCTCGGCAGCTTGGATCCTAGCATGACTATACATTGTGACATGGTCATTACATATGGATTAGACCAACTGGAGAATTGCCAGACTTGTG GTACCGATTATATCATCTCAGTCTTGAATTTACTCACGCTGATTGTTGAACAGATAAATACGAAACTGCCATCATCATTTGTAGAAAAAC TGTTTATACCATCATCTAAACTACTATTCTTGCGTTATCATAAAGAAAAAGAGGTTGTTGCTGTAGCCCATGCTGTTTATCAAGCAGTGC TCAGCTTGAAGAATATTCCTGTTTTGGAGACTGCCTATAAGTTAATATTGGGAGAAATGACTTGTGCCCTAAACAACCTCCTACACAGTC TACAACTTCCTGAGGCCTGTTCTGAAATAAAACATGAGGCTTTTAAGAATCATGTGTTCAATGTAGACAATGCAAAATTTGTAGTTATAT TTGACCTCAGTGCCCTGACTACAATTGGAAATGCCAAAAACTCACTAATAGGGATGTGGGCGCTATCTCCAACTGTCTTTGCACTTCTGA GTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCCATTCAGTATGCTGTGCTCTACACATTGTATTCTCATTGTA CCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCTTTGTTTGATGGAGCTGTGATTAGCACTGTAACTACGGCTA CAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAGAAAGATAACCTTAACCAGGACACGAGGAAACTGTTAATGA CTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCACCTTTATTCTCTCTTCCGTCTTTCCATAAATTTTGCAAAG GCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCATGCAGCAGTCTACATGCTCTGTCCTCTTCCTTGCCAGATG ATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGTGGAACTCGTATTCGACAAGCATTTGGAAAACTGTTGAAAT CAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAAGAAATTTCTTTAGCATTAAGAAGTCACATGAGTAAAGCAC CAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATTTTGTATGGGAACTCTCATAGAACAGGGAAGGACAATTGGT TGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCAACAATTCCACGCAATCTCCTGAAGACAGATGCTGTCCTTT GGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTGAGAACCCCACTGGGCAGAGCTCAAGACACCTTCCAGACAA TTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAGGATGTTAGTCAGTGGACAACTGCAGACAATGATGAAGGCC ATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAATCTGGAGAAATTAATGTATAATGCATACGAGGGATGTGCTA ATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAATCGCCAAACTTGTCAGGACTGGCTAACGCGGATTCGACTCT CCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGACATGGCTTTGACTTGCTTACAGAGATGAAAACAACCAGCC TATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCATTATGTGAACTTCATTGTCCTGAAGCTATACAGGGAATTG CTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCAGTGGCTCAACAGGCTGAAGGGAGGTTTGAAAAGGCCTCTG TGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATCTCCAGCTTTGACAAATCGGTGCTCACCTTAGCCAATGCTG GGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAAACTGTGCTGTCCAAACCGACTGACTCTTCCCCTGAGGTTA TAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGATTGGGCTGCTGTGCAGGAATGGCAGAACGCTATCCATGACT TGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAACTATATAAAATCATTAAGCAGCTTTGAGTCTGGAAAATTTG TTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTACTTGCTGGAGGATCAAAAGAAAAAATAGACATGAAAAAAC TGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATTGAAGTTCAATTGTTAAGAAGTTCTGTTTGTTTGGCAACTG CTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAATGTGGTAAAGTACTTGAAGCAAACATCCCGCATCGCTATTG GACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTAAGTACCTTGCAGCTGTATTGCTCATCTGCTTTGGAGAACA CAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGTGAAGCTTTACGTTCATGTAAACAGCATGACGTGAGGCCAT GGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAAATTAAAGGTATCTGGCTTGGAATTCTCGAAGGAATCGGTA TATTGGCTGTGATCACCAATGCATTTGTAATTGCTATTACTTCTGATTACATCCCACGTTTTGTTTATGAATACAAATATGGCCCCTGTG CAAATCATGTAGAACCAAGTGAAAATTGCTTGAAGGGATATGTCAACAATAGCCTATCCTTCTTTGACCTGAGTGAGCTTGGTATGGGAA AATCTGGTTATTGCAGGTACAGAGACTACAGAGGCCCGCCCTGGAGTTCCAAACCCTATGAGTTTACTTTACAATACTGGCATATCCTTG CTGCTAGATTGGCCTTCATTATTGTGTTTGAGCACCTTGTTTTTGGGATTAAGTCATTCATCGCATACCTGATTCCAGACGTACCAAAGG GTCTACATGACCGAATACGACGAGAGAAGTACTTAGTTCAAGAAATGATGTATGAGGCTGAACTGGAACATTTGCAACAACAACGGAGAA AAAGTGGTCAGCCTGTTCACCATGAATGGCCTTAGTTGACACCTGTTACCCATTAGGGGTGATAACATTAATGGGAAGAAATGATGGCAA CTTTGAATGCTAGGTGAAATCTAGGAGGAAGGCATACTTGGCAAACCACATGTATAATATGCTACTTGGAAATGTATCACAGCCATCTCT GGGATTTGAAATATCCAGACTTGTAGGGAAGAAAACAATGACTTGACGACCTTAAAAAGGGTTAGATTGACATTGCAGGAAGCCAGGATG >In-frame_ENST00000446231_ENST00000525139_TCGA-A2-A0EY-01A_SMG1_chr16_18869492_-_ANO3_chr11_26669256_length(amino acids)=1653AA_start in transcript=203_stop in transcript=5164 MRCGLRRNPERPSSSPALRRLLLLLLLLLLLLLGFLLSPGPERGVGGGRFGRRLALLWAAALGHVVSGKVMSRRAPGSRLSSGGGGGGTK YPRSWNDWQPRTDSASADPDNLKYSSSRDRGGSSSYGLQPSNSAVVSRQRHDDTRVHADIQNDEKGGYSVNGGSGENTYGRKSLGQELRV NNVTSPEFTSVQHGSRALATKDMRKSQERSMSYSDESRLSNLLRRITREDDRDRRLATVKQLKEFIQQPENKLVLVKQLDNILAAVHDVL NESSKLLQELRQEGACCLGLLCASLSYEAEKIFKWIFSKFSSSAKDEVKLLYLCATYKALETVGEKKAFSSVMQLVMTSLQSILENVDTP ELLCKCVKCILLVARCYPHIFSTNFRDTVDILVGWHIDHTQKPSLTQQVSGWLQSLEPFWVADLAFSTTLLGQFLEDMEAYAEDLSHVAS GESVDEDVPPPSVSLPKLAALLRVFSTVVRSIGERFSPIRGPPITEAYVTDVLYRVMRCVTAANQVFFSEAVLTAANECVGVLLGSLDPS MTIHCDMVITYGLDQLENCQTCGTDYIISVLNLLTLIVEQINTKLPSSFVEKLFIPSSKLLFLRYHKEKEVVAVAHAVYQAVLSLKNIPV LETAYKLILGEMTCALNNLLHSLQLPEACSEIKHEAFKNHVFNVDNAKFVVIFDLSALTTIGNAKNSLIGMWALSPTVFALLSKNLMIVH SDLAVHFPAIQYAVLYTLYSHCTRHDHFISSSLSSSSPSLFDGAVISTVTTATKKHFSIILNLLGILLKKDNLNQDTRKLLMTWALEAAV LMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNICLQACSSLHALSSSLPDDLLQRCVDVCRVQLVHSGTRIRQAFGKLLKSIPLDVVL SNNNHTEIQEISLALRSHMSKAPSNTFHPQDFSDVISFILYGNSHRTGKDNWLERLFYSCQRLDKRDQSTIPRNLLKTDAVLWQWAIWEA AQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTADNDEGHGNNQLRLVLLLQYLENLEKLMYNAYEGCANALTSPPK VIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLTEMKTTSLSQGNELEVTIMMVVEALCELHCPEAIQGIAVWSSSIV GKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVDCCISSFDKSVLTLANAGRNSASPKHSLNGESRKTVLSKPTDSSPEVINYLGNKA CECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLKADFNYIKSLSSFESGKFVECTEQLELLPGENINLLAGGSKEKIDMKKLLPNMLSP DPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQSITENVVKYLKQTSRIAIGPLRLSTLTVSQSLPVLSTLQLYCSSALENTVSNRLST EDCLIPLFSEALRSCKQHDVRPWMQALRYTMYQNQLLEKIKGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSE NCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRR -------------------------------------------------------------- >In-frame_ENST00000446231_ENST00000256737_TCGA-A2-A0EY-01A_SMG1_chr16_18869492_-_ANO3_chr11_26669256_length(transcript)=8009nt_BP=4647nt GTGCGACAGCGGCGGCGCGGCGGGCGGAGCCGGGAGGCGGGGAAGCAGTGGCCGTGTGAGCGTGAGGAGCTGCCGCCACCGCCTGCTCCT CGTCGTCCTCGTCCTCCGGGGCCCCGGCGACGTGGGCCGCGCACGGCCCTGGAAAAGACGTCGCCTCCCCTTCATCCGCCTCTCTCTCAC CGCGCCGCTCCCGCCTCCTCGTCCTGCGCTGCGGGCTCAGGCGGAACCCGGAACGGCCGTCCTCTTCCCCCGCCCTCCGCCGCCTCCTCC TTCTCCTCCTCCTCCTCCTCCTCCTCCTTCTCGGCTTCCTCCTCAGCCCCGGGCCGGAGCGGGGTGTCGGCGGCGGCCGGTTCGGGCGGC GACTCGCGCTTCTTTGGGCGGCGGCGCTTGGCCATGTCGTGTCGGGGAAGGTAATGAGCCGCAGAGCCCCGGGGTCTCGGCTGAGCAGCG GCGGCGGCGGCGGCGGCACCAAGTATCCGCGGAGCTGGAATGACTGGCAACCCAGAACTGATAGTGCATCAGCCGACCCAGATAATTTAA AATATTCTTCATCCAGAGATAGAGGTGGTTCTTCCTCTTATGGACTGCAACCTTCAAATTCAGCTGTGGTGTCTCGGCAAAGGCACGATG ATACCAGAGTCCACGCTGACATACAGAATGACGAAAAGGGTGGCTACAGTGTCAATGGAGGATCTGGGGAAAATACTTATGGTCGGAAGT CGTTGGGGCAAGAGCTGAGGGTTAACAATGTGACCAGCCCTGAGTTCACCAGTGTTCAGCATGGCAGTCGTGCTTTAGCCACCAAAGACA TGAGGAAATCACAGGAGAGATCGATGTCTTATTCTGATGAGTCTCGACTGTCGAATCTTCTTCGGAGGATCACCCGGGAAGACGACAGAG ACCGAAGATTGGCTACTGTAAAGCAGTTGAAAGAATTTATTCAGCAACCAGAAAATAAGCTGGTACTAGTTAAACAATTGGATAATATCT TGGCTGCTGTACATGACGTGCTTAATGAAAGTAGCAAATTGCTTCAGGAGTTGAGACAGGAGGGAGCTTGCTGTCTTGGCCTTCTTTGTG CTTCTCTGAGCTATGAGGCTGAGAAGATCTTCAAGTGGATTTTTAGCAAATTTAGCTCATCTGCAAAAGATGAAGTTAAACTCCTCTACT TATGTGCCACCTACAAAGCACTAGAGACTGTAGGAGAAAAGAAAGCCTTTTCATCTGTAATGCAGCTTGTAATGACCAGCCTGCAGTCTA TTCTTGAAAATGTGGATACACCAGAATTGCTTTGTAAATGTGTTAAGTGCATTCTTTTGGTGGCTCGATGTTACCCTCATATTTTCAGCA CTAATTTTAGGGATACAGTTGATATATTAGTTGGATGGCATATAGATCATACTCAGAAACCTTCGCTCACGCAGCAGGTATCTGGGTGGT TGCAGAGTTTGGAGCCATTTTGGGTAGCTGATCTTGCATTTTCTACTACTCTTCTTGGTCAGTTTCTGGAAGACATGGAAGCATATGCTG AGGACCTCAGCCATGTGGCCTCTGGGGAATCAGTGGATGAAGATGTCCCTCCTCCATCAGTGTCATTACCAAAGCTGGCTGCACTTCTCC GGGTATTTAGTACTGTGGTGAGGAGCATTGGGGAACGCTTCAGCCCAATTCGGGGTCCTCCAATTACTGAGGCATATGTAACAGATGTTC TGTACAGAGTAATGAGATGTGTGACGGCTGCAAACCAGGTGTTTTTTTCTGAGGCTGTGTTGACAGCTGCTAATGAGTGTGTTGGTGTTT TGCTCGGCAGCTTGGATCCTAGCATGACTATACATTGTGACATGGTCATTACATATGGATTAGACCAACTGGAGAATTGCCAGACTTGTG GTACCGATTATATCATCTCAGTCTTGAATTTACTCACGCTGATTGTTGAACAGATAAATACGAAACTGCCATCATCATTTGTAGAAAAAC TGTTTATACCATCATCTAAACTACTATTCTTGCGTTATCATAAAGAAAAAGAGGTTGTTGCTGTAGCCCATGCTGTTTATCAAGCAGTGC TCAGCTTGAAGAATATTCCTGTTTTGGAGACTGCCTATAAGTTAATATTGGGAGAAATGACTTGTGCCCTAAACAACCTCCTACACAGTC TACAACTTCCTGAGGCCTGTTCTGAAATAAAACATGAGGCTTTTAAGAATCATGTGTTCAATGTAGACAATGCAAAATTTGTAGTTATAT TTGACCTCAGTGCCCTGACTACAATTGGAAATGCCAAAAACTCACTAATAGGGATGTGGGCGCTATCTCCAACTGTCTTTGCACTTCTGA GTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCCATTCAGTATGCTGTGCTCTACACATTGTATTCTCATTGTA CCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCTTTGTTTGATGGAGCTGTGATTAGCACTGTAACTACGGCTA CAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAGAAAGATAACCTTAACCAGGACACGAGGAAACTGTTAATGA CTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCACCTTTATTCTCTCTTCCGTCTTTCCATAAATTTTGCAAAG GCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCATGCAGCAGTCTACATGCTCTGTCCTCTTCCTTGCCAGATG ATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGTGGAACTCGTATTCGACAAGCATTTGGAAAACTGTTGAAAT CAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAAGAAATTTCTTTAGCATTAAGAAGTCACATGAGTAAAGCAC CAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATTTTGTATGGGAACTCTCATAGAACAGGGAAGGACAATTGGT TGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCAACAATTCCACGCAATCTCCTGAAGACAGATGCTGTCCTTT GGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTGAGAACCCCACTGGGCAGAGCTCAAGACACCTTCCAGACAA TTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAGGATGTTAGTCAGTGGACAACTGCAGACAATGATGAAGGCC ATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAATCTGGAGAAATTAATGTATAATGCATACGAGGGATGTGCTA ATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAATCGCCAAACTTGTCAGGACTGGCTAACGCGGATTCGACTCT CCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGACATGGCTTTGACTTGCTTACAGAGATGAAAACAACCAGCC TATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCATTATGTGAACTTCATTGTCCTGAAGCTATACAGGGAATTG CTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCAGTGGCTCAACAGGCTGAAGGGAGGTTTGAAAAGGCCTCTG TGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATCTCCAGCTTTGACAAATCGGTGCTCACCTTAGCCAATGCTG GGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAAACTGTGCTGTCCAAACCGACTGACTCTTCCCCTGAGGTTA TAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGATTGGGCTGCTGTGCAGGAATGGCAGAACGCTATCCATGACT TGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAACTATATAAAATCATTAAGCAGCTTTGAGTCTGGAAAATTTG TTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTACTTGCTGGAGGATCAAAAGAAAAAATAGACATGAAAAAAC TGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATTGAAGTTCAATTGTTAAGAAGTTCTGTTTGTTTGGCAACTG CTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAATGTGGTAAAGTACTTGAAGCAAACATCCCGCATCGCTATTG GACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTAAGTACCTTGCAGCTGTATTGCTCATCTGCTTTGGAGAACA CAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGTGAAGCTTTACGTTCATGTAAACAGCATGACGTGAGGCCAT GGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAAATTAAAGGTATCTGGCTTGGAATTCTCGAAGGAATCGGTA TATTGGCTGTGATCACCAATGCATTTGTAATTGCTATTACTTCTGATTACATCCCACGTTTTGTTTATGAATACAAATATGGCCCCTGTG CAAATCATGTAGAACCAAGTGAAAATTGCTTGAAGGGATATGTCAACAATAGCCTATCCTTCTTTGACCTGAGTGAGCTTGGTATGGGAA AATCTGGTTATTGCAGGTACAGAGACTACAGAGGCCCGCCCTGGAGTTCCAAACCCTATGAGTTTACTTTACAATACTGGCATATCCTTG CTGCTAGATTGGCCTTCATTATTGTGTTTGAGCACCTTGTTTTTGGGATTAAGTCATTCATCGCATACCTGATTCCAGACGTACCAAAGG GTCTACATGACCGAATACGACGAGAGAAGTACTTAGTTCAAGAAATGATGTATGAGGCTGAACTGGAACATTTGCAACAACAACGGAGAA AAAGTGGTCAGCCTGTTCACCATGAATGGCCTTAGTTGACACCTGTTACCCATTAGGGGTGATAACATTAATGGGAAGAAATGATGGCAA CTTTGAATGCTAGGTGAAATCTAGGAGGAAGGCATACTTGGCAAACCACATGTATAATATGCTACTTGGAAATGTATCACAGCCATCTCT GGGATTTGAAATATCCAGACTTGTAGGGAAGAAAACAATGACTTGACGACCTTAAAAAGGGTTAGATTGACATTGCAGGAAGCCAGGATG TAATTCTCAGAACCAGTCTCAGGGAGATATATGCTTGGAGAACTCTGCCTTCCATCAACTGCAGTGTAATGGGAAAGAGGGTGGTGAGGT TTTGAAAGACAGATTTCCATGTAAATGTGCACAAGCCAGGCATGGCTTAAAATATCATGCAGTCTTCACTCACATACTAATTTGACTTTG GAAAGTATGGTTGAGTTCAGATACTTATAAGAAATGACTTAAACAAATCCTTGCCTTGGCTGCCAGAACTCTACATCCCTTCAGTTTACA GGTTGGTAGGAATTGCCCATGTCTCTTGCTGAGATTATGGATCTGTGCCACAGGGGATTTATGCTGCTTTACATTGACTATGCAGTTGAA GAGTTGCACATCACCTTTAGTAGTCAAACCAAAAATCTAAGATTCCAAAAAGAACAGCATTCATTGAAATAATATTCCATTGCATTGGCT ACTTCAAGTCTCTTTTACCCCTGGCAGAGCCAGTTGCAGTGCAATTTTTTGTACTAAATGCCAATAAAGCCACATACTTATAAACTATGA ATGGCTATTCTTATATAGTTTAGAACACAACTAATCCATACTTTATTGTGGAAGGCTGTTTTATAGTTTATTTAATTTTTTCTCTATGAT TTATTACAACTCTCACGGAATATTAACTTGAAATGCTGTAAATACGTTGGTTTTCCTTGTCCCTTTGCACCTTGACAGTACGTAGTATAC ATTGTGGTTTATGCAGCTCTGACACCAGTTTTTGCTATTGTAATATGTTTATTCGGGAAAACTGAGGCCAGATGCTCTGCAACACTTACG CTTTTTCAACAATGTGCACTCTTACTCATGAACTAATGAAAATAATGCATGAATATAAATCTATATTATTTGCTAAAAAAAGAAAAAACA TTTGTGTTTTAGTTTCTTTTTTCATGACTGAAGGGAGTTTTATGTTATTATTTCTTCCATAGTTTTGTTTTGGTTTATTTTTAACAACGC TCTAGAAACAAAGTCAAATTAATCACAAAAGACATAATTTTGCTTTGTTGTGGAATTTCTATTTCAACGTCAACTCTGTATCTATGAGTA TGTCTGTTCCACAGACAGATGAGGCAGGAGTGATGGGGCACTCAAGAAAGTTCAGAGGAGGCATAAGCTATGGAGGTTGGAAAGGAAGAA AGAGAAGAGCTGAAGTAAATGTATGGTAGAAATTAAGACGTTTCTTTGCAAAACAAGGAAATCACACATATGCACACATACATATTTATG GTTACTATGATTGTTATTATTTGTCCAATCAAGCAAAGCACCATTATTTCTAACATATAAAAGACCAGATCAAACACAATGGAAATAAAG CTACTACATATATATGCCAGTATTTCTCTAGTAAGATTATGTTTCTCTTACTAGAAAACTATTTTCTAAATATTAACACTGAAAATGTTT TGTTAGCTTTTCCTTCTTTCTCTCCAGAAGAAACATGGATAGATGATAGCTGTTTCATTGTTTGTTTTTGTCAAGCATATTCACTTTCCT CCTTGTCCTCTGATTCTGAGCAAAGGGCCTCAGACTCTGAACTTCCCTCAAGTGCCGTTGTTATGTGAAACTCTTCCATTCAGATTCCAG AGAGGTTCTCATGCTCCCCCCCCTCCTTATTTGTAGCAATCGTAGCAACTAATTCCACTAAGTACAAGGGAGTTTTTTACACTCCTCCAT TTTTATAGCATCTGCATTTCTTTTTCTTTGTTAGGTACATGTATACACCTGCCTGAGTATAAATACTCTCTCTACCTAATAATAACATCA ACCAACATCTTTTCCAAATTAGGGCCACAGAACAGCAACATTTGTCTGACAGTAGTATAAAGAATAATGATAGCTCTATCCTTAAGAAGT ATTTCCTTTCCTTTTTATATAGTCCCGTTAGGGTTTAAAACCATATTGATCAACTAGAAAGAAAAATATGAAAAGAGAAAAATATTTTAA TTTAAAAATTGTAATACATTGATTTATAAAATGCCTTCTCTGATACTTTTGAAACAGATGTGAAAAACAGAAAAAGAAAAAATTGTCTGA AATGTTTATTTTGCAAAACAGTGCAATAGAATCTAGTTATGCCTTCATCACTGTTGACAGTAAATACTGACAGCCCCTTGCAGTGTGTTA GTTTTAGATCACTCTGTTTTAGTTGAGAGAAATGTTTTATATCATGGTTTTTATATGAATACAAATTATTTCTCAAAGATTTATAGCACA CACTATTCTCAGGAATTCTGTATTACATGAATGCTGCTTATATATTTTCATATTCTAACTTGTCTTTTCAAGCAAATAACTAATATATAT GTGCATGCAGTCTGCCTTGACAAGTTGTTCCAAGCTGAAGAGCTTTCACTGTACAATGTGTGGAAAATCACCATAGATCATGGCTGAAAT AGTTTGTAATTGTCTGAGTCTGTGCACGTACTTTTAGATAAAATGCTGCTGAGTGACTGCATGATGAGATACAACTTCTGAATGCTGCAC >In-frame_ENST00000446231_ENST00000256737_TCGA-A2-A0EY-01A_SMG1_chr16_18869492_-_ANO3_chr11_26669256_length(amino acids)=1653AA_start in transcript=203_stop in transcript=5164 MRCGLRRNPERPSSSPALRRLLLLLLLLLLLLLGFLLSPGPERGVGGGRFGRRLALLWAAALGHVVSGKVMSRRAPGSRLSSGGGGGGTK YPRSWNDWQPRTDSASADPDNLKYSSSRDRGGSSSYGLQPSNSAVVSRQRHDDTRVHADIQNDEKGGYSVNGGSGENTYGRKSLGQELRV NNVTSPEFTSVQHGSRALATKDMRKSQERSMSYSDESRLSNLLRRITREDDRDRRLATVKQLKEFIQQPENKLVLVKQLDNILAAVHDVL NESSKLLQELRQEGACCLGLLCASLSYEAEKIFKWIFSKFSSSAKDEVKLLYLCATYKALETVGEKKAFSSVMQLVMTSLQSILENVDTP ELLCKCVKCILLVARCYPHIFSTNFRDTVDILVGWHIDHTQKPSLTQQVSGWLQSLEPFWVADLAFSTTLLGQFLEDMEAYAEDLSHVAS GESVDEDVPPPSVSLPKLAALLRVFSTVVRSIGERFSPIRGPPITEAYVTDVLYRVMRCVTAANQVFFSEAVLTAANECVGVLLGSLDPS MTIHCDMVITYGLDQLENCQTCGTDYIISVLNLLTLIVEQINTKLPSSFVEKLFIPSSKLLFLRYHKEKEVVAVAHAVYQAVLSLKNIPV LETAYKLILGEMTCALNNLLHSLQLPEACSEIKHEAFKNHVFNVDNAKFVVIFDLSALTTIGNAKNSLIGMWALSPTVFALLSKNLMIVH SDLAVHFPAIQYAVLYTLYSHCTRHDHFISSSLSSSSPSLFDGAVISTVTTATKKHFSIILNLLGILLKKDNLNQDTRKLLMTWALEAAV LMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNICLQACSSLHALSSSLPDDLLQRCVDVCRVQLVHSGTRIRQAFGKLLKSIPLDVVL SNNNHTEIQEISLALRSHMSKAPSNTFHPQDFSDVISFILYGNSHRTGKDNWLERLFYSCQRLDKRDQSTIPRNLLKTDAVLWQWAIWEA AQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTADNDEGHGNNQLRLVLLLQYLENLEKLMYNAYEGCANALTSPPK VIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLTEMKTTSLSQGNELEVTIMMVVEALCELHCPEAIQGIAVWSSSIV GKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVDCCISSFDKSVLTLANAGRNSASPKHSLNGESRKTVLSKPTDSSPEVINYLGNKA CECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLKADFNYIKSLSSFESGKFVECTEQLELLPGENINLLAGGSKEKIDMKKLLPNMLSP DPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQSITENVVKYLKQTSRIAIGPLRLSTLTVSQSLPVLSTLQLYCSSALENTVSNRLST EDCLIPLFSEALRSCKQHDVRPWMQALRYTMYQNQLLEKIKGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSE NCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRR -------------------------------------------------------------- >In-frame_ENST00000389467_ENST00000537978_TCGA-A2-A0EY_SMG1_chr16_18869491_-_ANO3_chr11_26669255_length(transcript)=5351nt_BP=4597nt GCCGTGTGAGCGTGAGGAGCTGCCGCCACCGCCTGCTCCTCGTCGTCCTCGTCCTCCGGGGCCCCGGCGACGTGGGCCGCGCACGGCCCT GGAAAAGACGTCGCCTCCCCTTCATCCGCCTCTCTCTCACCGCGCCGCTCCCGCCTCCTCGTCCTGCGCTGCGGGCTCAGGCGGAACCCG GAACGGCCGTCCTCTTCCCCCGCCCTCCGCCGCCTCCTCCTTCTCCTCCTCCTCCTCCTCCTCCTCCTTCTCGGCTTCCTCCTCAGCCCC GGGCCGGAGCGGGGTGTCGGCGGCGGCCGGTTCGGGCGGCGACTCGCGCTTCTTTGGGCGGCGGCGCTTGGCCATGTCGTGTCGGGGAAG GTAATGAGCCGCAGAGCCCCGGGGTCTCGGCTGAGCAGCGGCGGCGGCGGCGGCGGCACCAAGTATCCGCGGAGCTGGAATGACTGGCAA CCCAGAACTGATAGTGCATCAGCCGACCCAGATAATTTAAAATATTCTTCATCCAGAGATAGAGGTGGTTCTTCCTCTTATGGACTGCAA CCTTCAAATTCAGCTGTGGTGTCTCGGCAAAGGCACGATGATACCAGAGTCCACGCTGACATACAGAATGACGAAAAGGGTGGCTACAGT GTCAATGGAGGATCTGGGGAAAATACTTATGGTCGGAAGTCGTTGGGGCAAGAGCTGAGGGTTAACAATGTGACCAGCCCTGAGTTCACC AGTGTTCAGCATGGCAGTCGTGCTTTAGCCACCAAAGACATGAGGAAATCACAGGAGAGATCGATGTCTTATTCTGATGAGTCTCGACTG TCGAATCTTCTTCGGAGGATCACCCGGGAAGACGACAGAGACCGAAGATTGGCTACTGTAAAGCAGTTGAAAGAATTTATTCAGCAACCA GAAAATAAGCTGGTACTAGTTAAACAATTGGATAATATCTTGGCTGCTGTACATGACGTGCTTAATGAAAGTAGCAAATTGCTTCAGGAG TTGAGACAGGAGGGAGCTTGCTGTCTTGGCCTTCTTTGTGCTTCTCTGAGCTATGAGGCTGAGAAGATCTTCAAGTGGATTTTTAGCAAA TTTAGCTCATCTGCAAAAGATGAAGTTAAACTCCTCTACTTATGTGCCACCTACAAAGCACTAGAGACTGTAGGAGAAAAGAAAGCCTTT TCATCTGTAATGCAGCTTGTAATGACCAGCCTGCAGTCTATTCTTGAAAATGTGGATACACCAGAATTGCTTTGTAAATGTGTTAAGTGC ATTCTTTTGGTGGCTCGATGTTACCCTCATATTTTCAGCACTAATTTTAGGGATACAGTTGATATATTAGTTGGATGGCATATAGATCAT ACTCAGAAACCTTCGCTCACGCAGCAGGTATCTGGGTGGTTGCAGAGTTTGGAGCCATTTTGGGTAGCTGATCTTGCATTTTCTACTACT CTTCTTGGTCAGTTTCTGGAAGACATGGAAGCATATGCTGAGGACCTCAGCCATGTGGCCTCTGGGGAATCAGTGGATGAAGATGTCCCT CCTCCATCAGTGTCATTACCAAAGCTGGCTGCACTTCTCCGGGTATTTAGTACTGTGGTGAGGAGCATTGGGGAACGCTTCAGCCCAATT CGGGGTCCTCCAATTACTGAGGCATATGTAACAGATGTTCTGTACAGAGTAATGAGATGTGTGACGGCTGCAAACCAGGTGTTTTTTTCT GAGGCTGTGTTGACAGCTGCTAATGAGTGTGTTGGTGTTTTGCTCGGCAGCTTGGATCCTAGCATGACTATACATTGTGACATGGTCATT ACATATGGATTAGACCAACTGGAGAATTGCCAGACTTGTGGTACCGATTATATCATCTCAGTCTTGAATTTACTCACGCTGATTGTTGAA CAGATAAATACGAAACTGCCATCATCATTTGTAGAAAAACTGTTTATACCATCATCTAAACTACTATTCTTGCGTTATCATAAAGAAAAA GAGGTTGTTGCTGTAGCCCATGCTGTTTATCAAGCAGTGCTCAGCTTGAAGAATATTCCTGTTTTGGAGACTGCCTATAAGTTAATATTG GGAGAAATGACTTGTGCCCTAAACAACCTCCTACACAGTCTACAACTTCCTGAGGCCTGTTCTGAAATAAAACATGAGGCTTTTAAGAAT CATGTGTTCAATGTAGACAATGCAAAATTTGTAGTTATATTTGACCTCAGTGCCCTGACTACAATTGGAAATGCCAAAAACTCACTAATA GGGATGTGGGCGCTATCTCCAACTGTCTTTGCACTTCTGAGTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCC ATTCAGTATGCTGTGCTCTACACATTGTATTCTCATTGTACCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCT TTGTTTGATGGAGCTGTGATTAGCACTGTAACTACGGCTACAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAG AAAGATAACCTTAACCAGGACACGAGGAAACTGTTAATGACTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCA CCTTTATTCTCTCTTCCGTCTTTCCATAAATTTTGCAAAGGCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCA TGCAGCAGTCTACATGCTCTGTCCTCTTCCTTGCCAGATGATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGT GGAACTCGTATTCGACAAGCATTTGGAAAACTGTTGAAATCAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAA GAAATTTCTTTAGCATTAAGAAGTCACATGAGTAAAGCACCAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATT TTGTATGGGAACTCTCATAGAACAGGGAAGGACAATTGGTTGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCA ACAATTCCACGCAATCTCCTGAAGACAGATGCTGTCCTTTGGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTG AGAACCCCACTGGGCAGAGCTCAAGACACCTTCCAGACAATTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAG GATGTTAGTCAGTGGACAACTGCAGACAATGATGAAGGCCATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAAT CTGGAGAAATTAATGTATAATGCATACGAGGGATGTGCTAATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAAT CGCCAAACTTGTCAGGACTGGCTAACGCGGATTCGACTCTCCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGA CATGGCTTTGACTTGCTTACAGAGATGAAAACAACCAGCCTATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCA TTATGTGAACTTCATTGTCCTGAAGCTATACAGGGAATTGCTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCA GTGGCTCAACAGGCTGAAGGGAGGTTTGAAAAGGCCTCTGTGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATC TCCAGCTTTGACAAATCGGTGCTCACCTTAGCCAATGCTGGGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAA ACTGTGCTGTCCAAACCGACTGACTCTTCCCCTGAGGTTATAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGAT TGGGCTGCTGTGCAGGAATGGCAGAACGCTATCCATGACTTGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAAC TATATAAAATCATTAAGCAGCTTTGAGTCTGGAAAATTTGTTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTA CTTGCTGGAGGATCAAAAGAAAAAATAGACATGAAAAAACTGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATT GAAGTTCAATTGTTAAGAAGTTCTGTTTGTTTGGCAACTGCTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAAT GTGGTAAAGTACTTGAAGCAAACATCCCGCATCGCTATTGGACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTA AGTACCTTGCAGCTGTATTGCTCATCTGCTTTGGAGAACACAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGT GAAGCTTTACGTTCATGTAAACAGCATGACGTGAGGCCATGGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAA ATTAAAGGTATCTGGCTTGGAATTCTCGAAGGAATCGGTATATTGGCTGTGATCACCAATGCATTTGTAATTGCTATTACTTCTGATTAC ATCCCACGTTTTGTTTATGAATACAAATATGGCCCCTGTGCAAATCATGTAGAACCAAGTGAAAATTGCTTGAAGGGATATGTCAACAAT AGCCTATCCTTCTTTGACCTGAGTGAGCTTGGTATGGGAAAATCTGGTTATTGCAGGTACAGAGACTACAGAGGCCCGCCCTGGAGTTCC AAACCCTATGAGTTTACTTTACAATACTGGCATATCCTTGCTGCTAGATTGGCCTTCATTATTGTGTTTGAGCACCTTGTTTTTGGGATT AAGTCATTCATCGCATACCTGATTCCAGACGTACCAAAGGGTCTACATGACCGAATACGACGAGAGAAGTACTTAGTTCAAGAAATGATG TATGAGGCTGAACTGGAACATTTGCAACAACAACGGAGAAAAAGTGGTCAGCCTGTTCACCATGAATGGCCTTAGTTGACACCTGTTACC CATTAGGGGTGATAACATTAATGGGAAGAAATGATGGCAACTTTGAATGCTAGGTGAAATCTAGGAGGAAGGCATACTTGGCAAACCACA TGTATAATATGCTACTTGGAAATGTATCACAGCCATCTCTGGGATTTGAAATATCCAGACTTGTAGGGAAGAAAACAATGACTTGACGAC >In-frame_ENST00000389467_ENST00000537978_TCGA-A2-A0EY_SMG1_chr16_18869491_-_ANO3_chr11_26669255_length(amino acids)=1653AA_start in transcript=153_stop in transcript=5114 MRCGLRRNPERPSSSPALRRLLLLLLLLLLLLLGFLLSPGPERGVGGGRFGRRLALLWAAALGHVVSGKVMSRRAPGSRLSSGGGGGGTK YPRSWNDWQPRTDSASADPDNLKYSSSRDRGGSSSYGLQPSNSAVVSRQRHDDTRVHADIQNDEKGGYSVNGGSGENTYGRKSLGQELRV NNVTSPEFTSVQHGSRALATKDMRKSQERSMSYSDESRLSNLLRRITREDDRDRRLATVKQLKEFIQQPENKLVLVKQLDNILAAVHDVL NESSKLLQELRQEGACCLGLLCASLSYEAEKIFKWIFSKFSSSAKDEVKLLYLCATYKALETVGEKKAFSSVMQLVMTSLQSILENVDTP ELLCKCVKCILLVARCYPHIFSTNFRDTVDILVGWHIDHTQKPSLTQQVSGWLQSLEPFWVADLAFSTTLLGQFLEDMEAYAEDLSHVAS GESVDEDVPPPSVSLPKLAALLRVFSTVVRSIGERFSPIRGPPITEAYVTDVLYRVMRCVTAANQVFFSEAVLTAANECVGVLLGSLDPS MTIHCDMVITYGLDQLENCQTCGTDYIISVLNLLTLIVEQINTKLPSSFVEKLFIPSSKLLFLRYHKEKEVVAVAHAVYQAVLSLKNIPV LETAYKLILGEMTCALNNLLHSLQLPEACSEIKHEAFKNHVFNVDNAKFVVIFDLSALTTIGNAKNSLIGMWALSPTVFALLSKNLMIVH SDLAVHFPAIQYAVLYTLYSHCTRHDHFISSSLSSSSPSLFDGAVISTVTTATKKHFSIILNLLGILLKKDNLNQDTRKLLMTWALEAAV LMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNICLQACSSLHALSSSLPDDLLQRCVDVCRVQLVHSGTRIRQAFGKLLKSIPLDVVL SNNNHTEIQEISLALRSHMSKAPSNTFHPQDFSDVISFILYGNSHRTGKDNWLERLFYSCQRLDKRDQSTIPRNLLKTDAVLWQWAIWEA AQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTADNDEGHGNNQLRLVLLLQYLENLEKLMYNAYEGCANALTSPPK VIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLTEMKTTSLSQGNELEVTIMMVVEALCELHCPEAIQGIAVWSSSIV GKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVDCCISSFDKSVLTLANAGRNSASPKHSLNGESRKTVLSKPTDSSPEVINYLGNKA CECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLKADFNYIKSLSSFESGKFVECTEQLELLPGENINLLAGGSKEKIDMKKLLPNMLSP DPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQSITENVVKYLKQTSRIAIGPLRLSTLTVSQSLPVLSTLQLYCSSALENTVSNRLST EDCLIPLFSEALRSCKQHDVRPWMQALRYTMYQNQLLEKIKGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSE NCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRR -------------------------------------------------------------- >In-frame_ENST00000389467_ENST00000525139_TCGA-A2-A0EY_SMG1_chr16_18869491_-_ANO3_chr11_26669255_length(transcript)=5351nt_BP=4597nt GCCGTGTGAGCGTGAGGAGCTGCCGCCACCGCCTGCTCCTCGTCGTCCTCGTCCTCCGGGGCCCCGGCGACGTGGGCCGCGCACGGCCCT GGAAAAGACGTCGCCTCCCCTTCATCCGCCTCTCTCTCACCGCGCCGCTCCCGCCTCCTCGTCCTGCGCTGCGGGCTCAGGCGGAACCCG GAACGGCCGTCCTCTTCCCCCGCCCTCCGCCGCCTCCTCCTTCTCCTCCTCCTCCTCCTCCTCCTCCTTCTCGGCTTCCTCCTCAGCCCC GGGCCGGAGCGGGGTGTCGGCGGCGGCCGGTTCGGGCGGCGACTCGCGCTTCTTTGGGCGGCGGCGCTTGGCCATGTCGTGTCGGGGAAG GTAATGAGCCGCAGAGCCCCGGGGTCTCGGCTGAGCAGCGGCGGCGGCGGCGGCGGCACCAAGTATCCGCGGAGCTGGAATGACTGGCAA CCCAGAACTGATAGTGCATCAGCCGACCCAGATAATTTAAAATATTCTTCATCCAGAGATAGAGGTGGTTCTTCCTCTTATGGACTGCAA CCTTCAAATTCAGCTGTGGTGTCTCGGCAAAGGCACGATGATACCAGAGTCCACGCTGACATACAGAATGACGAAAAGGGTGGCTACAGT GTCAATGGAGGATCTGGGGAAAATACTTATGGTCGGAAGTCGTTGGGGCAAGAGCTGAGGGTTAACAATGTGACCAGCCCTGAGTTCACC AGTGTTCAGCATGGCAGTCGTGCTTTAGCCACCAAAGACATGAGGAAATCACAGGAGAGATCGATGTCTTATTCTGATGAGTCTCGACTG TCGAATCTTCTTCGGAGGATCACCCGGGAAGACGACAGAGACCGAAGATTGGCTACTGTAAAGCAGTTGAAAGAATTTATTCAGCAACCA GAAAATAAGCTGGTACTAGTTAAACAATTGGATAATATCTTGGCTGCTGTACATGACGTGCTTAATGAAAGTAGCAAATTGCTTCAGGAG TTGAGACAGGAGGGAGCTTGCTGTCTTGGCCTTCTTTGTGCTTCTCTGAGCTATGAGGCTGAGAAGATCTTCAAGTGGATTTTTAGCAAA TTTAGCTCATCTGCAAAAGATGAAGTTAAACTCCTCTACTTATGTGCCACCTACAAAGCACTAGAGACTGTAGGAGAAAAGAAAGCCTTT TCATCTGTAATGCAGCTTGTAATGACCAGCCTGCAGTCTATTCTTGAAAATGTGGATACACCAGAATTGCTTTGTAAATGTGTTAAGTGC ATTCTTTTGGTGGCTCGATGTTACCCTCATATTTTCAGCACTAATTTTAGGGATACAGTTGATATATTAGTTGGATGGCATATAGATCAT ACTCAGAAACCTTCGCTCACGCAGCAGGTATCTGGGTGGTTGCAGAGTTTGGAGCCATTTTGGGTAGCTGATCTTGCATTTTCTACTACT CTTCTTGGTCAGTTTCTGGAAGACATGGAAGCATATGCTGAGGACCTCAGCCATGTGGCCTCTGGGGAATCAGTGGATGAAGATGTCCCT CCTCCATCAGTGTCATTACCAAAGCTGGCTGCACTTCTCCGGGTATTTAGTACTGTGGTGAGGAGCATTGGGGAACGCTTCAGCCCAATT CGGGGTCCTCCAATTACTGAGGCATATGTAACAGATGTTCTGTACAGAGTAATGAGATGTGTGACGGCTGCAAACCAGGTGTTTTTTTCT GAGGCTGTGTTGACAGCTGCTAATGAGTGTGTTGGTGTTTTGCTCGGCAGCTTGGATCCTAGCATGACTATACATTGTGACATGGTCATT ACATATGGATTAGACCAACTGGAGAATTGCCAGACTTGTGGTACCGATTATATCATCTCAGTCTTGAATTTACTCACGCTGATTGTTGAA CAGATAAATACGAAACTGCCATCATCATTTGTAGAAAAACTGTTTATACCATCATCTAAACTACTATTCTTGCGTTATCATAAAGAAAAA GAGGTTGTTGCTGTAGCCCATGCTGTTTATCAAGCAGTGCTCAGCTTGAAGAATATTCCTGTTTTGGAGACTGCCTATAAGTTAATATTG GGAGAAATGACTTGTGCCCTAAACAACCTCCTACACAGTCTACAACTTCCTGAGGCCTGTTCTGAAATAAAACATGAGGCTTTTAAGAAT CATGTGTTCAATGTAGACAATGCAAAATTTGTAGTTATATTTGACCTCAGTGCCCTGACTACAATTGGAAATGCCAAAAACTCACTAATA GGGATGTGGGCGCTATCTCCAACTGTCTTTGCACTTCTGAGTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCC ATTCAGTATGCTGTGCTCTACACATTGTATTCTCATTGTACCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCT TTGTTTGATGGAGCTGTGATTAGCACTGTAACTACGGCTACAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAG AAAGATAACCTTAACCAGGACACGAGGAAACTGTTAATGACTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCA CCTTTATTCTCTCTTCCGTCTTTCCATAAATTTTGCAAAGGCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCA TGCAGCAGTCTACATGCTCTGTCCTCTTCCTTGCCAGATGATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGT GGAACTCGTATTCGACAAGCATTTGGAAAACTGTTGAAATCAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAA GAAATTTCTTTAGCATTAAGAAGTCACATGAGTAAAGCACCAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATT TTGTATGGGAACTCTCATAGAACAGGGAAGGACAATTGGTTGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCA ACAATTCCACGCAATCTCCTGAAGACAGATGCTGTCCTTTGGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTG AGAACCCCACTGGGCAGAGCTCAAGACACCTTCCAGACAATTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAG GATGTTAGTCAGTGGACAACTGCAGACAATGATGAAGGCCATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAAT CTGGAGAAATTAATGTATAATGCATACGAGGGATGTGCTAATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAAT CGCCAAACTTGTCAGGACTGGCTAACGCGGATTCGACTCTCCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGA CATGGCTTTGACTTGCTTACAGAGATGAAAACAACCAGCCTATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCA TTATGTGAACTTCATTGTCCTGAAGCTATACAGGGAATTGCTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCA GTGGCTCAACAGGCTGAAGGGAGGTTTGAAAAGGCCTCTGTGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATC TCCAGCTTTGACAAATCGGTGCTCACCTTAGCCAATGCTGGGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAA ACTGTGCTGTCCAAACCGACTGACTCTTCCCCTGAGGTTATAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGAT TGGGCTGCTGTGCAGGAATGGCAGAACGCTATCCATGACTTGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAAC TATATAAAATCATTAAGCAGCTTTGAGTCTGGAAAATTTGTTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTA CTTGCTGGAGGATCAAAAGAAAAAATAGACATGAAAAAACTGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATT GAAGTTCAATTGTTAAGAAGTTCTGTTTGTTTGGCAACTGCTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAAT GTGGTAAAGTACTTGAAGCAAACATCCCGCATCGCTATTGGACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTA AGTACCTTGCAGCTGTATTGCTCATCTGCTTTGGAGAACACAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGT GAAGCTTTACGTTCATGTAAACAGCATGACGTGAGGCCATGGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAA ATTAAAGGTATCTGGCTTGGAATTCTCGAAGGAATCGGTATATTGGCTGTGATCACCAATGCATTTGTAATTGCTATTACTTCTGATTAC ATCCCACGTTTTGTTTATGAATACAAATATGGCCCCTGTGCAAATCATGTAGAACCAAGTGAAAATTGCTTGAAGGGATATGTCAACAAT AGCCTATCCTTCTTTGACCTGAGTGAGCTTGGTATGGGAAAATCTGGTTATTGCAGGTACAGAGACTACAGAGGCCCGCCCTGGAGTTCC AAACCCTATGAGTTTACTTTACAATACTGGCATATCCTTGCTGCTAGATTGGCCTTCATTATTGTGTTTGAGCACCTTGTTTTTGGGATT AAGTCATTCATCGCATACCTGATTCCAGACGTACCAAAGGGTCTACATGACCGAATACGACGAGAGAAGTACTTAGTTCAAGAAATGATG TATGAGGCTGAACTGGAACATTTGCAACAACAACGGAGAAAAAGTGGTCAGCCTGTTCACCATGAATGGCCTTAGTTGACACCTGTTACC CATTAGGGGTGATAACATTAATGGGAAGAAATGATGGCAACTTTGAATGCTAGGTGAAATCTAGGAGGAAGGCATACTTGGCAAACCACA TGTATAATATGCTACTTGGAAATGTATCACAGCCATCTCTGGGATTTGAAATATCCAGACTTGTAGGGAAGAAAACAATGACTTGACGAC >In-frame_ENST00000389467_ENST00000525139_TCGA-A2-A0EY_SMG1_chr16_18869491_-_ANO3_chr11_26669255_length(amino acids)=1653AA_start in transcript=153_stop in transcript=5114 MRCGLRRNPERPSSSPALRRLLLLLLLLLLLLLGFLLSPGPERGVGGGRFGRRLALLWAAALGHVVSGKVMSRRAPGSRLSSGGGGGGTK YPRSWNDWQPRTDSASADPDNLKYSSSRDRGGSSSYGLQPSNSAVVSRQRHDDTRVHADIQNDEKGGYSVNGGSGENTYGRKSLGQELRV NNVTSPEFTSVQHGSRALATKDMRKSQERSMSYSDESRLSNLLRRITREDDRDRRLATVKQLKEFIQQPENKLVLVKQLDNILAAVHDVL NESSKLLQELRQEGACCLGLLCASLSYEAEKIFKWIFSKFSSSAKDEVKLLYLCATYKALETVGEKKAFSSVMQLVMTSLQSILENVDTP ELLCKCVKCILLVARCYPHIFSTNFRDTVDILVGWHIDHTQKPSLTQQVSGWLQSLEPFWVADLAFSTTLLGQFLEDMEAYAEDLSHVAS GESVDEDVPPPSVSLPKLAALLRVFSTVVRSIGERFSPIRGPPITEAYVTDVLYRVMRCVTAANQVFFSEAVLTAANECVGVLLGSLDPS MTIHCDMVITYGLDQLENCQTCGTDYIISVLNLLTLIVEQINTKLPSSFVEKLFIPSSKLLFLRYHKEKEVVAVAHAVYQAVLSLKNIPV LETAYKLILGEMTCALNNLLHSLQLPEACSEIKHEAFKNHVFNVDNAKFVVIFDLSALTTIGNAKNSLIGMWALSPTVFALLSKNLMIVH SDLAVHFPAIQYAVLYTLYSHCTRHDHFISSSLSSSSPSLFDGAVISTVTTATKKHFSIILNLLGILLKKDNLNQDTRKLLMTWALEAAV LMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNICLQACSSLHALSSSLPDDLLQRCVDVCRVQLVHSGTRIRQAFGKLLKSIPLDVVL SNNNHTEIQEISLALRSHMSKAPSNTFHPQDFSDVISFILYGNSHRTGKDNWLERLFYSCQRLDKRDQSTIPRNLLKTDAVLWQWAIWEA AQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTADNDEGHGNNQLRLVLLLQYLENLEKLMYNAYEGCANALTSPPK VIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLTEMKTTSLSQGNELEVTIMMVVEALCELHCPEAIQGIAVWSSSIV GKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVDCCISSFDKSVLTLANAGRNSASPKHSLNGESRKTVLSKPTDSSPEVINYLGNKA CECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLKADFNYIKSLSSFESGKFVECTEQLELLPGENINLLAGGSKEKIDMKKLLPNMLSP DPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQSITENVVKYLKQTSRIAIGPLRLSTLTVSQSLPVLSTLQLYCSSALENTVSNRLST EDCLIPLFSEALRSCKQHDVRPWMQALRYTMYQNQLLEKIKGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSE NCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRR -------------------------------------------------------------- >In-frame_ENST00000389467_ENST00000256737_TCGA-A2-A0EY_SMG1_chr16_18869491_-_ANO3_chr11_26669255_length(transcript)=7959nt_BP=4597nt GCCGTGTGAGCGTGAGGAGCTGCCGCCACCGCCTGCTCCTCGTCGTCCTCGTCCTCCGGGGCCCCGGCGACGTGGGCCGCGCACGGCCCT GGAAAAGACGTCGCCTCCCCTTCATCCGCCTCTCTCTCACCGCGCCGCTCCCGCCTCCTCGTCCTGCGCTGCGGGCTCAGGCGGAACCCG GAACGGCCGTCCTCTTCCCCCGCCCTCCGCCGCCTCCTCCTTCTCCTCCTCCTCCTCCTCCTCCTCCTTCTCGGCTTCCTCCTCAGCCCC GGGCCGGAGCGGGGTGTCGGCGGCGGCCGGTTCGGGCGGCGACTCGCGCTTCTTTGGGCGGCGGCGCTTGGCCATGTCGTGTCGGGGAAG GTAATGAGCCGCAGAGCCCCGGGGTCTCGGCTGAGCAGCGGCGGCGGCGGCGGCGGCACCAAGTATCCGCGGAGCTGGAATGACTGGCAA CCCAGAACTGATAGTGCATCAGCCGACCCAGATAATTTAAAATATTCTTCATCCAGAGATAGAGGTGGTTCTTCCTCTTATGGACTGCAA CCTTCAAATTCAGCTGTGGTGTCTCGGCAAAGGCACGATGATACCAGAGTCCACGCTGACATACAGAATGACGAAAAGGGTGGCTACAGT GTCAATGGAGGATCTGGGGAAAATACTTATGGTCGGAAGTCGTTGGGGCAAGAGCTGAGGGTTAACAATGTGACCAGCCCTGAGTTCACC AGTGTTCAGCATGGCAGTCGTGCTTTAGCCACCAAAGACATGAGGAAATCACAGGAGAGATCGATGTCTTATTCTGATGAGTCTCGACTG TCGAATCTTCTTCGGAGGATCACCCGGGAAGACGACAGAGACCGAAGATTGGCTACTGTAAAGCAGTTGAAAGAATTTATTCAGCAACCA GAAAATAAGCTGGTACTAGTTAAACAATTGGATAATATCTTGGCTGCTGTACATGACGTGCTTAATGAAAGTAGCAAATTGCTTCAGGAG TTGAGACAGGAGGGAGCTTGCTGTCTTGGCCTTCTTTGTGCTTCTCTGAGCTATGAGGCTGAGAAGATCTTCAAGTGGATTTTTAGCAAA TTTAGCTCATCTGCAAAAGATGAAGTTAAACTCCTCTACTTATGTGCCACCTACAAAGCACTAGAGACTGTAGGAGAAAAGAAAGCCTTT TCATCTGTAATGCAGCTTGTAATGACCAGCCTGCAGTCTATTCTTGAAAATGTGGATACACCAGAATTGCTTTGTAAATGTGTTAAGTGC ATTCTTTTGGTGGCTCGATGTTACCCTCATATTTTCAGCACTAATTTTAGGGATACAGTTGATATATTAGTTGGATGGCATATAGATCAT ACTCAGAAACCTTCGCTCACGCAGCAGGTATCTGGGTGGTTGCAGAGTTTGGAGCCATTTTGGGTAGCTGATCTTGCATTTTCTACTACT CTTCTTGGTCAGTTTCTGGAAGACATGGAAGCATATGCTGAGGACCTCAGCCATGTGGCCTCTGGGGAATCAGTGGATGAAGATGTCCCT CCTCCATCAGTGTCATTACCAAAGCTGGCTGCACTTCTCCGGGTATTTAGTACTGTGGTGAGGAGCATTGGGGAACGCTTCAGCCCAATT CGGGGTCCTCCAATTACTGAGGCATATGTAACAGATGTTCTGTACAGAGTAATGAGATGTGTGACGGCTGCAAACCAGGTGTTTTTTTCT GAGGCTGTGTTGACAGCTGCTAATGAGTGTGTTGGTGTTTTGCTCGGCAGCTTGGATCCTAGCATGACTATACATTGTGACATGGTCATT ACATATGGATTAGACCAACTGGAGAATTGCCAGACTTGTGGTACCGATTATATCATCTCAGTCTTGAATTTACTCACGCTGATTGTTGAA CAGATAAATACGAAACTGCCATCATCATTTGTAGAAAAACTGTTTATACCATCATCTAAACTACTATTCTTGCGTTATCATAAAGAAAAA GAGGTTGTTGCTGTAGCCCATGCTGTTTATCAAGCAGTGCTCAGCTTGAAGAATATTCCTGTTTTGGAGACTGCCTATAAGTTAATATTG GGAGAAATGACTTGTGCCCTAAACAACCTCCTACACAGTCTACAACTTCCTGAGGCCTGTTCTGAAATAAAACATGAGGCTTTTAAGAAT CATGTGTTCAATGTAGACAATGCAAAATTTGTAGTTATATTTGACCTCAGTGCCCTGACTACAATTGGAAATGCCAAAAACTCACTAATA GGGATGTGGGCGCTATCTCCAACTGTCTTTGCACTTCTGAGTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCC ATTCAGTATGCTGTGCTCTACACATTGTATTCTCATTGTACCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCT TTGTTTGATGGAGCTGTGATTAGCACTGTAACTACGGCTACAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAG AAAGATAACCTTAACCAGGACACGAGGAAACTGTTAATGACTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCA CCTTTATTCTCTCTTCCGTCTTTCCATAAATTTTGCAAAGGCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCA TGCAGCAGTCTACATGCTCTGTCCTCTTCCTTGCCAGATGATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGT GGAACTCGTATTCGACAAGCATTTGGAAAACTGTTGAAATCAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAA GAAATTTCTTTAGCATTAAGAAGTCACATGAGTAAAGCACCAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATT TTGTATGGGAACTCTCATAGAACAGGGAAGGACAATTGGTTGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCA ACAATTCCACGCAATCTCCTGAAGACAGATGCTGTCCTTTGGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTG AGAACCCCACTGGGCAGAGCTCAAGACACCTTCCAGACAATTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAG GATGTTAGTCAGTGGACAACTGCAGACAATGATGAAGGCCATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAAT CTGGAGAAATTAATGTATAATGCATACGAGGGATGTGCTAATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAAT CGCCAAACTTGTCAGGACTGGCTAACGCGGATTCGACTCTCCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGA CATGGCTTTGACTTGCTTACAGAGATGAAAACAACCAGCCTATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCA TTATGTGAACTTCATTGTCCTGAAGCTATACAGGGAATTGCTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCA GTGGCTCAACAGGCTGAAGGGAGGTTTGAAAAGGCCTCTGTGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATC TCCAGCTTTGACAAATCGGTGCTCACCTTAGCCAATGCTGGGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAA ACTGTGCTGTCCAAACCGACTGACTCTTCCCCTGAGGTTATAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGAT TGGGCTGCTGTGCAGGAATGGCAGAACGCTATCCATGACTTGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAAC TATATAAAATCATTAAGCAGCTTTGAGTCTGGAAAATTTGTTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTA CTTGCTGGAGGATCAAAAGAAAAAATAGACATGAAAAAACTGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATT GAAGTTCAATTGTTAAGAAGTTCTGTTTGTTTGGCAACTGCTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAAT GTGGTAAAGTACTTGAAGCAAACATCCCGCATCGCTATTGGACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTA AGTACCTTGCAGCTGTATTGCTCATCTGCTTTGGAGAACACAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGT GAAGCTTTACGTTCATGTAAACAGCATGACGTGAGGCCATGGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAA ATTAAAGGTATCTGGCTTGGAATTCTCGAAGGAATCGGTATATTGGCTGTGATCACCAATGCATTTGTAATTGCTATTACTTCTGATTAC ATCCCACGTTTTGTTTATGAATACAAATATGGCCCCTGTGCAAATCATGTAGAACCAAGTGAAAATTGCTTGAAGGGATATGTCAACAAT AGCCTATCCTTCTTTGACCTGAGTGAGCTTGGTATGGGAAAATCTGGTTATTGCAGGTACAGAGACTACAGAGGCCCGCCCTGGAGTTCC AAACCCTATGAGTTTACTTTACAATACTGGCATATCCTTGCTGCTAGATTGGCCTTCATTATTGTGTTTGAGCACCTTGTTTTTGGGATT AAGTCATTCATCGCATACCTGATTCCAGACGTACCAAAGGGTCTACATGACCGAATACGACGAGAGAAGTACTTAGTTCAAGAAATGATG TATGAGGCTGAACTGGAACATTTGCAACAACAACGGAGAAAAAGTGGTCAGCCTGTTCACCATGAATGGCCTTAGTTGACACCTGTTACC CATTAGGGGTGATAACATTAATGGGAAGAAATGATGGCAACTTTGAATGCTAGGTGAAATCTAGGAGGAAGGCATACTTGGCAAACCACA TGTATAATATGCTACTTGGAAATGTATCACAGCCATCTCTGGGATTTGAAATATCCAGACTTGTAGGGAAGAAAACAATGACTTGACGAC CTTAAAAAGGGTTAGATTGACATTGCAGGAAGCCAGGATGTAATTCTCAGAACCAGTCTCAGGGAGATATATGCTTGGAGAACTCTGCCT TCCATCAACTGCAGTGTAATGGGAAAGAGGGTGGTGAGGTTTTGAAAGACAGATTTCCATGTAAATGTGCACAAGCCAGGCATGGCTTAA AATATCATGCAGTCTTCACTCACATACTAATTTGACTTTGGAAAGTATGGTTGAGTTCAGATACTTATAAGAAATGACTTAAACAAATCC TTGCCTTGGCTGCCAGAACTCTACATCCCTTCAGTTTACAGGTTGGTAGGAATTGCCCATGTCTCTTGCTGAGATTATGGATCTGTGCCA CAGGGGATTTATGCTGCTTTACATTGACTATGCAGTTGAAGAGTTGCACATCACCTTTAGTAGTCAAACCAAAAATCTAAGATTCCAAAA AGAACAGCATTCATTGAAATAATATTCCATTGCATTGGCTACTTCAAGTCTCTTTTACCCCTGGCAGAGCCAGTTGCAGTGCAATTTTTT GTACTAAATGCCAATAAAGCCACATACTTATAAACTATGAATGGCTATTCTTATATAGTTTAGAACACAACTAATCCATACTTTATTGTG GAAGGCTGTTTTATAGTTTATTTAATTTTTTCTCTATGATTTATTACAACTCTCACGGAATATTAACTTGAAATGCTGTAAATACGTTGG TTTTCCTTGTCCCTTTGCACCTTGACAGTACGTAGTATACATTGTGGTTTATGCAGCTCTGACACCAGTTTTTGCTATTGTAATATGTTT ATTCGGGAAAACTGAGGCCAGATGCTCTGCAACACTTACGCTTTTTCAACAATGTGCACTCTTACTCATGAACTAATGAAAATAATGCAT GAATATAAATCTATATTATTTGCTAAAAAAAGAAAAAACATTTGTGTTTTAGTTTCTTTTTTCATGACTGAAGGGAGTTTTATGTTATTA TTTCTTCCATAGTTTTGTTTTGGTTTATTTTTAACAACGCTCTAGAAACAAAGTCAAATTAATCACAAAAGACATAATTTTGCTTTGTTG TGGAATTTCTATTTCAACGTCAACTCTGTATCTATGAGTATGTCTGTTCCACAGACAGATGAGGCAGGAGTGATGGGGCACTCAAGAAAG TTCAGAGGAGGCATAAGCTATGGAGGTTGGAAAGGAAGAAAGAGAAGAGCTGAAGTAAATGTATGGTAGAAATTAAGACGTTTCTTTGCA AAACAAGGAAATCACACATATGCACACATACATATTTATGGTTACTATGATTGTTATTATTTGTCCAATCAAGCAAAGCACCATTATTTC TAACATATAAAAGACCAGATCAAACACAATGGAAATAAAGCTACTACATATATATGCCAGTATTTCTCTAGTAAGATTATGTTTCTCTTA CTAGAAAACTATTTTCTAAATATTAACACTGAAAATGTTTTGTTAGCTTTTCCTTCTTTCTCTCCAGAAGAAACATGGATAGATGATAGC TGTTTCATTGTTTGTTTTTGTCAAGCATATTCACTTTCCTCCTTGTCCTCTGATTCTGAGCAAAGGGCCTCAGACTCTGAACTTCCCTCA AGTGCCGTTGTTATGTGAAACTCTTCCATTCAGATTCCAGAGAGGTTCTCATGCTCCCCCCCCTCCTTATTTGTAGCAATCGTAGCAACT AATTCCACTAAGTACAAGGGAGTTTTTTACACTCCTCCATTTTTATAGCATCTGCATTTCTTTTTCTTTGTTAGGTACATGTATACACCT GCCTGAGTATAAATACTCTCTCTACCTAATAATAACATCAACCAACATCTTTTCCAAATTAGGGCCACAGAACAGCAACATTTGTCTGAC AGTAGTATAAAGAATAATGATAGCTCTATCCTTAAGAAGTATTTCCTTTCCTTTTTATATAGTCCCGTTAGGGTTTAAAACCATATTGAT CAACTAGAAAGAAAAATATGAAAAGAGAAAAATATTTTAATTTAAAAATTGTAATACATTGATTTATAAAATGCCTTCTCTGATACTTTT GAAACAGATGTGAAAAACAGAAAAAGAAAAAATTGTCTGAAATGTTTATTTTGCAAAACAGTGCAATAGAATCTAGTTATGCCTTCATCA CTGTTGACAGTAAATACTGACAGCCCCTTGCAGTGTGTTAGTTTTAGATCACTCTGTTTTAGTTGAGAGAAATGTTTTATATCATGGTTT TTATATGAATACAAATTATTTCTCAAAGATTTATAGCACACACTATTCTCAGGAATTCTGTATTACATGAATGCTGCTTATATATTTTCA TATTCTAACTTGTCTTTTCAAGCAAATAACTAATATATATGTGCATGCAGTCTGCCTTGACAAGTTGTTCCAAGCTGAAGAGCTTTCACT GTACAATGTGTGGAAAATCACCATAGATCATGGCTGAAATAGTTTGTAATTGTCTGAGTCTGTGCACGTACTTTTAGATAAAATGCTGCT GAGTGACTGCATGATGAGATACAACTTCTGAATGCTGCACATTCTTCCAAAATGATCCTTAGCACAATCTATTGTATGATGGAATGAATA >In-frame_ENST00000389467_ENST00000256737_TCGA-A2-A0EY_SMG1_chr16_18869491_-_ANO3_chr11_26669255_length(amino acids)=1653AA_start in transcript=153_stop in transcript=5114 MRCGLRRNPERPSSSPALRRLLLLLLLLLLLLLGFLLSPGPERGVGGGRFGRRLALLWAAALGHVVSGKVMSRRAPGSRLSSGGGGGGTK YPRSWNDWQPRTDSASADPDNLKYSSSRDRGGSSSYGLQPSNSAVVSRQRHDDTRVHADIQNDEKGGYSVNGGSGENTYGRKSLGQELRV NNVTSPEFTSVQHGSRALATKDMRKSQERSMSYSDESRLSNLLRRITREDDRDRRLATVKQLKEFIQQPENKLVLVKQLDNILAAVHDVL NESSKLLQELRQEGACCLGLLCASLSYEAEKIFKWIFSKFSSSAKDEVKLLYLCATYKALETVGEKKAFSSVMQLVMTSLQSILENVDTP ELLCKCVKCILLVARCYPHIFSTNFRDTVDILVGWHIDHTQKPSLTQQVSGWLQSLEPFWVADLAFSTTLLGQFLEDMEAYAEDLSHVAS GESVDEDVPPPSVSLPKLAALLRVFSTVVRSIGERFSPIRGPPITEAYVTDVLYRVMRCVTAANQVFFSEAVLTAANECVGVLLGSLDPS MTIHCDMVITYGLDQLENCQTCGTDYIISVLNLLTLIVEQINTKLPSSFVEKLFIPSSKLLFLRYHKEKEVVAVAHAVYQAVLSLKNIPV LETAYKLILGEMTCALNNLLHSLQLPEACSEIKHEAFKNHVFNVDNAKFVVIFDLSALTTIGNAKNSLIGMWALSPTVFALLSKNLMIVH SDLAVHFPAIQYAVLYTLYSHCTRHDHFISSSLSSSSPSLFDGAVISTVTTATKKHFSIILNLLGILLKKDNLNQDTRKLLMTWALEAAV LMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNICLQACSSLHALSSSLPDDLLQRCVDVCRVQLVHSGTRIRQAFGKLLKSIPLDVVL SNNNHTEIQEISLALRSHMSKAPSNTFHPQDFSDVISFILYGNSHRTGKDNWLERLFYSCQRLDKRDQSTIPRNLLKTDAVLWQWAIWEA AQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTADNDEGHGNNQLRLVLLLQYLENLEKLMYNAYEGCANALTSPPK VIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLTEMKTTSLSQGNELEVTIMMVVEALCELHCPEAIQGIAVWSSSIV GKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVDCCISSFDKSVLTLANAGRNSASPKHSLNGESRKTVLSKPTDSSPEVINYLGNKA CECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLKADFNYIKSLSSFESGKFVECTEQLELLPGENINLLAGGSKEKIDMKKLLPNMLSP DPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQSITENVVKYLKQTSRIAIGPLRLSTLTVSQSLPVLSTLQLYCSSALENTVSNRLST EDCLIPLFSEALRSCKQHDVRPWMQALRYTMYQNQLLEKIKGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSE NCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRR -------------------------------------------------------------- >In-frame_ENST00000446231_ENST00000537978_TCGA-A2-A0EY_SMG1_chr16_18869491_-_ANO3_chr11_26669255_length(transcript)=5401nt_BP=4647nt GTGCGACAGCGGCGGCGCGGCGGGCGGAGCCGGGAGGCGGGGAAGCAGTGGCCGTGTGAGCGTGAGGAGCTGCCGCCACCGCCTGCTCCT CGTCGTCCTCGTCCTCCGGGGCCCCGGCGACGTGGGCCGCGCACGGCCCTGGAAAAGACGTCGCCTCCCCTTCATCCGCCTCTCTCTCAC CGCGCCGCTCCCGCCTCCTCGTCCTGCGCTGCGGGCTCAGGCGGAACCCGGAACGGCCGTCCTCTTCCCCCGCCCTCCGCCGCCTCCTCC TTCTCCTCCTCCTCCTCCTCCTCCTCCTTCTCGGCTTCCTCCTCAGCCCCGGGCCGGAGCGGGGTGTCGGCGGCGGCCGGTTCGGGCGGC GACTCGCGCTTCTTTGGGCGGCGGCGCTTGGCCATGTCGTGTCGGGGAAGGTAATGAGCCGCAGAGCCCCGGGGTCTCGGCTGAGCAGCG GCGGCGGCGGCGGCGGCACCAAGTATCCGCGGAGCTGGAATGACTGGCAACCCAGAACTGATAGTGCATCAGCCGACCCAGATAATTTAA AATATTCTTCATCCAGAGATAGAGGTGGTTCTTCCTCTTATGGACTGCAACCTTCAAATTCAGCTGTGGTGTCTCGGCAAAGGCACGATG ATACCAGAGTCCACGCTGACATACAGAATGACGAAAAGGGTGGCTACAGTGTCAATGGAGGATCTGGGGAAAATACTTATGGTCGGAAGT CGTTGGGGCAAGAGCTGAGGGTTAACAATGTGACCAGCCCTGAGTTCACCAGTGTTCAGCATGGCAGTCGTGCTTTAGCCACCAAAGACA TGAGGAAATCACAGGAGAGATCGATGTCTTATTCTGATGAGTCTCGACTGTCGAATCTTCTTCGGAGGATCACCCGGGAAGACGACAGAG ACCGAAGATTGGCTACTGTAAAGCAGTTGAAAGAATTTATTCAGCAACCAGAAAATAAGCTGGTACTAGTTAAACAATTGGATAATATCT TGGCTGCTGTACATGACGTGCTTAATGAAAGTAGCAAATTGCTTCAGGAGTTGAGACAGGAGGGAGCTTGCTGTCTTGGCCTTCTTTGTG CTTCTCTGAGCTATGAGGCTGAGAAGATCTTCAAGTGGATTTTTAGCAAATTTAGCTCATCTGCAAAAGATGAAGTTAAACTCCTCTACT TATGTGCCACCTACAAAGCACTAGAGACTGTAGGAGAAAAGAAAGCCTTTTCATCTGTAATGCAGCTTGTAATGACCAGCCTGCAGTCTA TTCTTGAAAATGTGGATACACCAGAATTGCTTTGTAAATGTGTTAAGTGCATTCTTTTGGTGGCTCGATGTTACCCTCATATTTTCAGCA CTAATTTTAGGGATACAGTTGATATATTAGTTGGATGGCATATAGATCATACTCAGAAACCTTCGCTCACGCAGCAGGTATCTGGGTGGT TGCAGAGTTTGGAGCCATTTTGGGTAGCTGATCTTGCATTTTCTACTACTCTTCTTGGTCAGTTTCTGGAAGACATGGAAGCATATGCTG AGGACCTCAGCCATGTGGCCTCTGGGGAATCAGTGGATGAAGATGTCCCTCCTCCATCAGTGTCATTACCAAAGCTGGCTGCACTTCTCC GGGTATTTAGTACTGTGGTGAGGAGCATTGGGGAACGCTTCAGCCCAATTCGGGGTCCTCCAATTACTGAGGCATATGTAACAGATGTTC TGTACAGAGTAATGAGATGTGTGACGGCTGCAAACCAGGTGTTTTTTTCTGAGGCTGTGTTGACAGCTGCTAATGAGTGTGTTGGTGTTT TGCTCGGCAGCTTGGATCCTAGCATGACTATACATTGTGACATGGTCATTACATATGGATTAGACCAACTGGAGAATTGCCAGACTTGTG GTACCGATTATATCATCTCAGTCTTGAATTTACTCACGCTGATTGTTGAACAGATAAATACGAAACTGCCATCATCATTTGTAGAAAAAC TGTTTATACCATCATCTAAACTACTATTCTTGCGTTATCATAAAGAAAAAGAGGTTGTTGCTGTAGCCCATGCTGTTTATCAAGCAGTGC TCAGCTTGAAGAATATTCCTGTTTTGGAGACTGCCTATAAGTTAATATTGGGAGAAATGACTTGTGCCCTAAACAACCTCCTACACAGTC TACAACTTCCTGAGGCCTGTTCTGAAATAAAACATGAGGCTTTTAAGAATCATGTGTTCAATGTAGACAATGCAAAATTTGTAGTTATAT TTGACCTCAGTGCCCTGACTACAATTGGAAATGCCAAAAACTCACTAATAGGGATGTGGGCGCTATCTCCAACTGTCTTTGCACTTCTGA GTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCCATTCAGTATGCTGTGCTCTACACATTGTATTCTCATTGTA CCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCTTTGTTTGATGGAGCTGTGATTAGCACTGTAACTACGGCTA CAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAGAAAGATAACCTTAACCAGGACACGAGGAAACTGTTAATGA CTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCACCTTTATTCTCTCTTCCGTCTTTCCATAAATTTTGCAAAG GCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCATGCAGCAGTCTACATGCTCTGTCCTCTTCCTTGCCAGATG ATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGTGGAACTCGTATTCGACAAGCATTTGGAAAACTGTTGAAAT CAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAAGAAATTTCTTTAGCATTAAGAAGTCACATGAGTAAAGCAC CAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATTTTGTATGGGAACTCTCATAGAACAGGGAAGGACAATTGGT TGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCAACAATTCCACGCAATCTCCTGAAGACAGATGCTGTCCTTT GGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTGAGAACCCCACTGGGCAGAGCTCAAGACACCTTCCAGACAA TTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAGGATGTTAGTCAGTGGACAACTGCAGACAATGATGAAGGCC ATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAATCTGGAGAAATTAATGTATAATGCATACGAGGGATGTGCTA ATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAATCGCCAAACTTGTCAGGACTGGCTAACGCGGATTCGACTCT CCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGACATGGCTTTGACTTGCTTACAGAGATGAAAACAACCAGCC TATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCATTATGTGAACTTCATTGTCCTGAAGCTATACAGGGAATTG CTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCAGTGGCTCAACAGGCTGAAGGGAGGTTTGAAAAGGCCTCTG TGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATCTCCAGCTTTGACAAATCGGTGCTCACCTTAGCCAATGCTG GGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAAACTGTGCTGTCCAAACCGACTGACTCTTCCCCTGAGGTTA TAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGATTGGGCTGCTGTGCAGGAATGGCAGAACGCTATCCATGACT TGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAACTATATAAAATCATTAAGCAGCTTTGAGTCTGGAAAATTTG TTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTACTTGCTGGAGGATCAAAAGAAAAAATAGACATGAAAAAAC TGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATTGAAGTTCAATTGTTAAGAAGTTCTGTTTGTTTGGCAACTG CTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAATGTGGTAAAGTACTTGAAGCAAACATCCCGCATCGCTATTG GACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTAAGTACCTTGCAGCTGTATTGCTCATCTGCTTTGGAGAACA CAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGTGAAGCTTTACGTTCATGTAAACAGCATGACGTGAGGCCAT GGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAAATTAAAGGTATCTGGCTTGGAATTCTCGAAGGAATCGGTA TATTGGCTGTGATCACCAATGCATTTGTAATTGCTATTACTTCTGATTACATCCCACGTTTTGTTTATGAATACAAATATGGCCCCTGTG CAAATCATGTAGAACCAAGTGAAAATTGCTTGAAGGGATATGTCAACAATAGCCTATCCTTCTTTGACCTGAGTGAGCTTGGTATGGGAA AATCTGGTTATTGCAGGTACAGAGACTACAGAGGCCCGCCCTGGAGTTCCAAACCCTATGAGTTTACTTTACAATACTGGCATATCCTTG CTGCTAGATTGGCCTTCATTATTGTGTTTGAGCACCTTGTTTTTGGGATTAAGTCATTCATCGCATACCTGATTCCAGACGTACCAAAGG GTCTACATGACCGAATACGACGAGAGAAGTACTTAGTTCAAGAAATGATGTATGAGGCTGAACTGGAACATTTGCAACAACAACGGAGAA AAAGTGGTCAGCCTGTTCACCATGAATGGCCTTAGTTGACACCTGTTACCCATTAGGGGTGATAACATTAATGGGAAGAAATGATGGCAA CTTTGAATGCTAGGTGAAATCTAGGAGGAAGGCATACTTGGCAAACCACATGTATAATATGCTACTTGGAAATGTATCACAGCCATCTCT GGGATTTGAAATATCCAGACTTGTAGGGAAGAAAACAATGACTTGACGACCTTAAAAAGGGTTAGATTGACATTGCAGGAAGCCAGGATG >In-frame_ENST00000446231_ENST00000537978_TCGA-A2-A0EY_SMG1_chr16_18869491_-_ANO3_chr11_26669255_length(amino acids)=1653AA_start in transcript=203_stop in transcript=5164 MRCGLRRNPERPSSSPALRRLLLLLLLLLLLLLGFLLSPGPERGVGGGRFGRRLALLWAAALGHVVSGKVMSRRAPGSRLSSGGGGGGTK YPRSWNDWQPRTDSASADPDNLKYSSSRDRGGSSSYGLQPSNSAVVSRQRHDDTRVHADIQNDEKGGYSVNGGSGENTYGRKSLGQELRV NNVTSPEFTSVQHGSRALATKDMRKSQERSMSYSDESRLSNLLRRITREDDRDRRLATVKQLKEFIQQPENKLVLVKQLDNILAAVHDVL NESSKLLQELRQEGACCLGLLCASLSYEAEKIFKWIFSKFSSSAKDEVKLLYLCATYKALETVGEKKAFSSVMQLVMTSLQSILENVDTP ELLCKCVKCILLVARCYPHIFSTNFRDTVDILVGWHIDHTQKPSLTQQVSGWLQSLEPFWVADLAFSTTLLGQFLEDMEAYAEDLSHVAS GESVDEDVPPPSVSLPKLAALLRVFSTVVRSIGERFSPIRGPPITEAYVTDVLYRVMRCVTAANQVFFSEAVLTAANECVGVLLGSLDPS MTIHCDMVITYGLDQLENCQTCGTDYIISVLNLLTLIVEQINTKLPSSFVEKLFIPSSKLLFLRYHKEKEVVAVAHAVYQAVLSLKNIPV LETAYKLILGEMTCALNNLLHSLQLPEACSEIKHEAFKNHVFNVDNAKFVVIFDLSALTTIGNAKNSLIGMWALSPTVFALLSKNLMIVH SDLAVHFPAIQYAVLYTLYSHCTRHDHFISSSLSSSSPSLFDGAVISTVTTATKKHFSIILNLLGILLKKDNLNQDTRKLLMTWALEAAV LMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNICLQACSSLHALSSSLPDDLLQRCVDVCRVQLVHSGTRIRQAFGKLLKSIPLDVVL SNNNHTEIQEISLALRSHMSKAPSNTFHPQDFSDVISFILYGNSHRTGKDNWLERLFYSCQRLDKRDQSTIPRNLLKTDAVLWQWAIWEA AQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTADNDEGHGNNQLRLVLLLQYLENLEKLMYNAYEGCANALTSPPK VIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLTEMKTTSLSQGNELEVTIMMVVEALCELHCPEAIQGIAVWSSSIV GKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVDCCISSFDKSVLTLANAGRNSASPKHSLNGESRKTVLSKPTDSSPEVINYLGNKA CECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLKADFNYIKSLSSFESGKFVECTEQLELLPGENINLLAGGSKEKIDMKKLLPNMLSP DPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQSITENVVKYLKQTSRIAIGPLRLSTLTVSQSLPVLSTLQLYCSSALENTVSNRLST EDCLIPLFSEALRSCKQHDVRPWMQALRYTMYQNQLLEKIKGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSE NCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRR -------------------------------------------------------------- >In-frame_ENST00000446231_ENST00000525139_TCGA-A2-A0EY_SMG1_chr16_18869491_-_ANO3_chr11_26669255_length(transcript)=5401nt_BP=4647nt GTGCGACAGCGGCGGCGCGGCGGGCGGAGCCGGGAGGCGGGGAAGCAGTGGCCGTGTGAGCGTGAGGAGCTGCCGCCACCGCCTGCTCCT CGTCGTCCTCGTCCTCCGGGGCCCCGGCGACGTGGGCCGCGCACGGCCCTGGAAAAGACGTCGCCTCCCCTTCATCCGCCTCTCTCTCAC CGCGCCGCTCCCGCCTCCTCGTCCTGCGCTGCGGGCTCAGGCGGAACCCGGAACGGCCGTCCTCTTCCCCCGCCCTCCGCCGCCTCCTCC TTCTCCTCCTCCTCCTCCTCCTCCTCCTTCTCGGCTTCCTCCTCAGCCCCGGGCCGGAGCGGGGTGTCGGCGGCGGCCGGTTCGGGCGGC GACTCGCGCTTCTTTGGGCGGCGGCGCTTGGCCATGTCGTGTCGGGGAAGGTAATGAGCCGCAGAGCCCCGGGGTCTCGGCTGAGCAGCG GCGGCGGCGGCGGCGGCACCAAGTATCCGCGGAGCTGGAATGACTGGCAACCCAGAACTGATAGTGCATCAGCCGACCCAGATAATTTAA AATATTCTTCATCCAGAGATAGAGGTGGTTCTTCCTCTTATGGACTGCAACCTTCAAATTCAGCTGTGGTGTCTCGGCAAAGGCACGATG ATACCAGAGTCCACGCTGACATACAGAATGACGAAAAGGGTGGCTACAGTGTCAATGGAGGATCTGGGGAAAATACTTATGGTCGGAAGT CGTTGGGGCAAGAGCTGAGGGTTAACAATGTGACCAGCCCTGAGTTCACCAGTGTTCAGCATGGCAGTCGTGCTTTAGCCACCAAAGACA TGAGGAAATCACAGGAGAGATCGATGTCTTATTCTGATGAGTCTCGACTGTCGAATCTTCTTCGGAGGATCACCCGGGAAGACGACAGAG ACCGAAGATTGGCTACTGTAAAGCAGTTGAAAGAATTTATTCAGCAACCAGAAAATAAGCTGGTACTAGTTAAACAATTGGATAATATCT TGGCTGCTGTACATGACGTGCTTAATGAAAGTAGCAAATTGCTTCAGGAGTTGAGACAGGAGGGAGCTTGCTGTCTTGGCCTTCTTTGTG CTTCTCTGAGCTATGAGGCTGAGAAGATCTTCAAGTGGATTTTTAGCAAATTTAGCTCATCTGCAAAAGATGAAGTTAAACTCCTCTACT TATGTGCCACCTACAAAGCACTAGAGACTGTAGGAGAAAAGAAAGCCTTTTCATCTGTAATGCAGCTTGTAATGACCAGCCTGCAGTCTA TTCTTGAAAATGTGGATACACCAGAATTGCTTTGTAAATGTGTTAAGTGCATTCTTTTGGTGGCTCGATGTTACCCTCATATTTTCAGCA CTAATTTTAGGGATACAGTTGATATATTAGTTGGATGGCATATAGATCATACTCAGAAACCTTCGCTCACGCAGCAGGTATCTGGGTGGT TGCAGAGTTTGGAGCCATTTTGGGTAGCTGATCTTGCATTTTCTACTACTCTTCTTGGTCAGTTTCTGGAAGACATGGAAGCATATGCTG AGGACCTCAGCCATGTGGCCTCTGGGGAATCAGTGGATGAAGATGTCCCTCCTCCATCAGTGTCATTACCAAAGCTGGCTGCACTTCTCC GGGTATTTAGTACTGTGGTGAGGAGCATTGGGGAACGCTTCAGCCCAATTCGGGGTCCTCCAATTACTGAGGCATATGTAACAGATGTTC TGTACAGAGTAATGAGATGTGTGACGGCTGCAAACCAGGTGTTTTTTTCTGAGGCTGTGTTGACAGCTGCTAATGAGTGTGTTGGTGTTT TGCTCGGCAGCTTGGATCCTAGCATGACTATACATTGTGACATGGTCATTACATATGGATTAGACCAACTGGAGAATTGCCAGACTTGTG GTACCGATTATATCATCTCAGTCTTGAATTTACTCACGCTGATTGTTGAACAGATAAATACGAAACTGCCATCATCATTTGTAGAAAAAC TGTTTATACCATCATCTAAACTACTATTCTTGCGTTATCATAAAGAAAAAGAGGTTGTTGCTGTAGCCCATGCTGTTTATCAAGCAGTGC TCAGCTTGAAGAATATTCCTGTTTTGGAGACTGCCTATAAGTTAATATTGGGAGAAATGACTTGTGCCCTAAACAACCTCCTACACAGTC TACAACTTCCTGAGGCCTGTTCTGAAATAAAACATGAGGCTTTTAAGAATCATGTGTTCAATGTAGACAATGCAAAATTTGTAGTTATAT TTGACCTCAGTGCCCTGACTACAATTGGAAATGCCAAAAACTCACTAATAGGGATGTGGGCGCTATCTCCAACTGTCTTTGCACTTCTGA GTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCCATTCAGTATGCTGTGCTCTACACATTGTATTCTCATTGTA CCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCTTTGTTTGATGGAGCTGTGATTAGCACTGTAACTACGGCTA CAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAGAAAGATAACCTTAACCAGGACACGAGGAAACTGTTAATGA CTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCACCTTTATTCTCTCTTCCGTCTTTCCATAAATTTTGCAAAG GCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCATGCAGCAGTCTACATGCTCTGTCCTCTTCCTTGCCAGATG ATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGTGGAACTCGTATTCGACAAGCATTTGGAAAACTGTTGAAAT CAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAAGAAATTTCTTTAGCATTAAGAAGTCACATGAGTAAAGCAC CAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATTTTGTATGGGAACTCTCATAGAACAGGGAAGGACAATTGGT TGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCAACAATTCCACGCAATCTCCTGAAGACAGATGCTGTCCTTT GGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTGAGAACCCCACTGGGCAGAGCTCAAGACACCTTCCAGACAA TTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAGGATGTTAGTCAGTGGACAACTGCAGACAATGATGAAGGCC ATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAATCTGGAGAAATTAATGTATAATGCATACGAGGGATGTGCTA ATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAATCGCCAAACTTGTCAGGACTGGCTAACGCGGATTCGACTCT CCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGACATGGCTTTGACTTGCTTACAGAGATGAAAACAACCAGCC TATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCATTATGTGAACTTCATTGTCCTGAAGCTATACAGGGAATTG CTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCAGTGGCTCAACAGGCTGAAGGGAGGTTTGAAAAGGCCTCTG TGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATCTCCAGCTTTGACAAATCGGTGCTCACCTTAGCCAATGCTG GGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAAACTGTGCTGTCCAAACCGACTGACTCTTCCCCTGAGGTTA TAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGATTGGGCTGCTGTGCAGGAATGGCAGAACGCTATCCATGACT TGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAACTATATAAAATCATTAAGCAGCTTTGAGTCTGGAAAATTTG TTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTACTTGCTGGAGGATCAAAAGAAAAAATAGACATGAAAAAAC TGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATTGAAGTTCAATTGTTAAGAAGTTCTGTTTGTTTGGCAACTG CTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAATGTGGTAAAGTACTTGAAGCAAACATCCCGCATCGCTATTG GACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTAAGTACCTTGCAGCTGTATTGCTCATCTGCTTTGGAGAACA CAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGTGAAGCTTTACGTTCATGTAAACAGCATGACGTGAGGCCAT GGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAAATTAAAGGTATCTGGCTTGGAATTCTCGAAGGAATCGGTA TATTGGCTGTGATCACCAATGCATTTGTAATTGCTATTACTTCTGATTACATCCCACGTTTTGTTTATGAATACAAATATGGCCCCTGTG CAAATCATGTAGAACCAAGTGAAAATTGCTTGAAGGGATATGTCAACAATAGCCTATCCTTCTTTGACCTGAGTGAGCTTGGTATGGGAA AATCTGGTTATTGCAGGTACAGAGACTACAGAGGCCCGCCCTGGAGTTCCAAACCCTATGAGTTTACTTTACAATACTGGCATATCCTTG CTGCTAGATTGGCCTTCATTATTGTGTTTGAGCACCTTGTTTTTGGGATTAAGTCATTCATCGCATACCTGATTCCAGACGTACCAAAGG GTCTACATGACCGAATACGACGAGAGAAGTACTTAGTTCAAGAAATGATGTATGAGGCTGAACTGGAACATTTGCAACAACAACGGAGAA AAAGTGGTCAGCCTGTTCACCATGAATGGCCTTAGTTGACACCTGTTACCCATTAGGGGTGATAACATTAATGGGAAGAAATGATGGCAA CTTTGAATGCTAGGTGAAATCTAGGAGGAAGGCATACTTGGCAAACCACATGTATAATATGCTACTTGGAAATGTATCACAGCCATCTCT GGGATTTGAAATATCCAGACTTGTAGGGAAGAAAACAATGACTTGACGACCTTAAAAAGGGTTAGATTGACATTGCAGGAAGCCAGGATG >In-frame_ENST00000446231_ENST00000525139_TCGA-A2-A0EY_SMG1_chr16_18869491_-_ANO3_chr11_26669255_length(amino acids)=1653AA_start in transcript=203_stop in transcript=5164 MRCGLRRNPERPSSSPALRRLLLLLLLLLLLLLGFLLSPGPERGVGGGRFGRRLALLWAAALGHVVSGKVMSRRAPGSRLSSGGGGGGTK YPRSWNDWQPRTDSASADPDNLKYSSSRDRGGSSSYGLQPSNSAVVSRQRHDDTRVHADIQNDEKGGYSVNGGSGENTYGRKSLGQELRV NNVTSPEFTSVQHGSRALATKDMRKSQERSMSYSDESRLSNLLRRITREDDRDRRLATVKQLKEFIQQPENKLVLVKQLDNILAAVHDVL NESSKLLQELRQEGACCLGLLCASLSYEAEKIFKWIFSKFSSSAKDEVKLLYLCATYKALETVGEKKAFSSVMQLVMTSLQSILENVDTP ELLCKCVKCILLVARCYPHIFSTNFRDTVDILVGWHIDHTQKPSLTQQVSGWLQSLEPFWVADLAFSTTLLGQFLEDMEAYAEDLSHVAS GESVDEDVPPPSVSLPKLAALLRVFSTVVRSIGERFSPIRGPPITEAYVTDVLYRVMRCVTAANQVFFSEAVLTAANECVGVLLGSLDPS MTIHCDMVITYGLDQLENCQTCGTDYIISVLNLLTLIVEQINTKLPSSFVEKLFIPSSKLLFLRYHKEKEVVAVAHAVYQAVLSLKNIPV LETAYKLILGEMTCALNNLLHSLQLPEACSEIKHEAFKNHVFNVDNAKFVVIFDLSALTTIGNAKNSLIGMWALSPTVFALLSKNLMIVH SDLAVHFPAIQYAVLYTLYSHCTRHDHFISSSLSSSSPSLFDGAVISTVTTATKKHFSIILNLLGILLKKDNLNQDTRKLLMTWALEAAV LMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNICLQACSSLHALSSSLPDDLLQRCVDVCRVQLVHSGTRIRQAFGKLLKSIPLDVVL SNNNHTEIQEISLALRSHMSKAPSNTFHPQDFSDVISFILYGNSHRTGKDNWLERLFYSCQRLDKRDQSTIPRNLLKTDAVLWQWAIWEA AQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTADNDEGHGNNQLRLVLLLQYLENLEKLMYNAYEGCANALTSPPK VIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLTEMKTTSLSQGNELEVTIMMVVEALCELHCPEAIQGIAVWSSSIV GKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVDCCISSFDKSVLTLANAGRNSASPKHSLNGESRKTVLSKPTDSSPEVINYLGNKA CECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLKADFNYIKSLSSFESGKFVECTEQLELLPGENINLLAGGSKEKIDMKKLLPNMLSP DPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQSITENVVKYLKQTSRIAIGPLRLSTLTVSQSLPVLSTLQLYCSSALENTVSNRLST EDCLIPLFSEALRSCKQHDVRPWMQALRYTMYQNQLLEKIKGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSE NCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRR -------------------------------------------------------------- >In-frame_ENST00000446231_ENST00000256737_TCGA-A2-A0EY_SMG1_chr16_18869491_-_ANO3_chr11_26669255_length(transcript)=8009nt_BP=4647nt GTGCGACAGCGGCGGCGCGGCGGGCGGAGCCGGGAGGCGGGGAAGCAGTGGCCGTGTGAGCGTGAGGAGCTGCCGCCACCGCCTGCTCCT CGTCGTCCTCGTCCTCCGGGGCCCCGGCGACGTGGGCCGCGCACGGCCCTGGAAAAGACGTCGCCTCCCCTTCATCCGCCTCTCTCTCAC CGCGCCGCTCCCGCCTCCTCGTCCTGCGCTGCGGGCTCAGGCGGAACCCGGAACGGCCGTCCTCTTCCCCCGCCCTCCGCCGCCTCCTCC TTCTCCTCCTCCTCCTCCTCCTCCTCCTTCTCGGCTTCCTCCTCAGCCCCGGGCCGGAGCGGGGTGTCGGCGGCGGCCGGTTCGGGCGGC GACTCGCGCTTCTTTGGGCGGCGGCGCTTGGCCATGTCGTGTCGGGGAAGGTAATGAGCCGCAGAGCCCCGGGGTCTCGGCTGAGCAGCG GCGGCGGCGGCGGCGGCACCAAGTATCCGCGGAGCTGGAATGACTGGCAACCCAGAACTGATAGTGCATCAGCCGACCCAGATAATTTAA AATATTCTTCATCCAGAGATAGAGGTGGTTCTTCCTCTTATGGACTGCAACCTTCAAATTCAGCTGTGGTGTCTCGGCAAAGGCACGATG ATACCAGAGTCCACGCTGACATACAGAATGACGAAAAGGGTGGCTACAGTGTCAATGGAGGATCTGGGGAAAATACTTATGGTCGGAAGT CGTTGGGGCAAGAGCTGAGGGTTAACAATGTGACCAGCCCTGAGTTCACCAGTGTTCAGCATGGCAGTCGTGCTTTAGCCACCAAAGACA TGAGGAAATCACAGGAGAGATCGATGTCTTATTCTGATGAGTCTCGACTGTCGAATCTTCTTCGGAGGATCACCCGGGAAGACGACAGAG ACCGAAGATTGGCTACTGTAAAGCAGTTGAAAGAATTTATTCAGCAACCAGAAAATAAGCTGGTACTAGTTAAACAATTGGATAATATCT TGGCTGCTGTACATGACGTGCTTAATGAAAGTAGCAAATTGCTTCAGGAGTTGAGACAGGAGGGAGCTTGCTGTCTTGGCCTTCTTTGTG CTTCTCTGAGCTATGAGGCTGAGAAGATCTTCAAGTGGATTTTTAGCAAATTTAGCTCATCTGCAAAAGATGAAGTTAAACTCCTCTACT TATGTGCCACCTACAAAGCACTAGAGACTGTAGGAGAAAAGAAAGCCTTTTCATCTGTAATGCAGCTTGTAATGACCAGCCTGCAGTCTA TTCTTGAAAATGTGGATACACCAGAATTGCTTTGTAAATGTGTTAAGTGCATTCTTTTGGTGGCTCGATGTTACCCTCATATTTTCAGCA CTAATTTTAGGGATACAGTTGATATATTAGTTGGATGGCATATAGATCATACTCAGAAACCTTCGCTCACGCAGCAGGTATCTGGGTGGT TGCAGAGTTTGGAGCCATTTTGGGTAGCTGATCTTGCATTTTCTACTACTCTTCTTGGTCAGTTTCTGGAAGACATGGAAGCATATGCTG AGGACCTCAGCCATGTGGCCTCTGGGGAATCAGTGGATGAAGATGTCCCTCCTCCATCAGTGTCATTACCAAAGCTGGCTGCACTTCTCC GGGTATTTAGTACTGTGGTGAGGAGCATTGGGGAACGCTTCAGCCCAATTCGGGGTCCTCCAATTACTGAGGCATATGTAACAGATGTTC TGTACAGAGTAATGAGATGTGTGACGGCTGCAAACCAGGTGTTTTTTTCTGAGGCTGTGTTGACAGCTGCTAATGAGTGTGTTGGTGTTT TGCTCGGCAGCTTGGATCCTAGCATGACTATACATTGTGACATGGTCATTACATATGGATTAGACCAACTGGAGAATTGCCAGACTTGTG GTACCGATTATATCATCTCAGTCTTGAATTTACTCACGCTGATTGTTGAACAGATAAATACGAAACTGCCATCATCATTTGTAGAAAAAC TGTTTATACCATCATCTAAACTACTATTCTTGCGTTATCATAAAGAAAAAGAGGTTGTTGCTGTAGCCCATGCTGTTTATCAAGCAGTGC TCAGCTTGAAGAATATTCCTGTTTTGGAGACTGCCTATAAGTTAATATTGGGAGAAATGACTTGTGCCCTAAACAACCTCCTACACAGTC TACAACTTCCTGAGGCCTGTTCTGAAATAAAACATGAGGCTTTTAAGAATCATGTGTTCAATGTAGACAATGCAAAATTTGTAGTTATAT TTGACCTCAGTGCCCTGACTACAATTGGAAATGCCAAAAACTCACTAATAGGGATGTGGGCGCTATCTCCAACTGTCTTTGCACTTCTGA GTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCCATTCAGTATGCTGTGCTCTACACATTGTATTCTCATTGTA CCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCTTTGTTTGATGGAGCTGTGATTAGCACTGTAACTACGGCTA CAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAGAAAGATAACCTTAACCAGGACACGAGGAAACTGTTAATGA CTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCACCTTTATTCTCTCTTCCGTCTTTCCATAAATTTTGCAAAG GCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCATGCAGCAGTCTACATGCTCTGTCCTCTTCCTTGCCAGATG ATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGTGGAACTCGTATTCGACAAGCATTTGGAAAACTGTTGAAAT CAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAAGAAATTTCTTTAGCATTAAGAAGTCACATGAGTAAAGCAC CAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATTTTGTATGGGAACTCTCATAGAACAGGGAAGGACAATTGGT TGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCAACAATTCCACGCAATCTCCTGAAGACAGATGCTGTCCTTT GGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTGAGAACCCCACTGGGCAGAGCTCAAGACACCTTCCAGACAA TTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAGGATGTTAGTCAGTGGACAACTGCAGACAATGATGAAGGCC ATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAATCTGGAGAAATTAATGTATAATGCATACGAGGGATGTGCTA ATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAATCGCCAAACTTGTCAGGACTGGCTAACGCGGATTCGACTCT CCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGACATGGCTTTGACTTGCTTACAGAGATGAAAACAACCAGCC TATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCATTATGTGAACTTCATTGTCCTGAAGCTATACAGGGAATTG CTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCAGTGGCTCAACAGGCTGAAGGGAGGTTTGAAAAGGCCTCTG TGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATCTCCAGCTTTGACAAATCGGTGCTCACCTTAGCCAATGCTG GGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAAACTGTGCTGTCCAAACCGACTGACTCTTCCCCTGAGGTTA TAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGATTGGGCTGCTGTGCAGGAATGGCAGAACGCTATCCATGACT TGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAACTATATAAAATCATTAAGCAGCTTTGAGTCTGGAAAATTTG TTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTACTTGCTGGAGGATCAAAAGAAAAAATAGACATGAAAAAAC TGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATTGAAGTTCAATTGTTAAGAAGTTCTGTTTGTTTGGCAACTG CTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAATGTGGTAAAGTACTTGAAGCAAACATCCCGCATCGCTATTG GACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTAAGTACCTTGCAGCTGTATTGCTCATCTGCTTTGGAGAACA CAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGTGAAGCTTTACGTTCATGTAAACAGCATGACGTGAGGCCAT GGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAAATTAAAGGTATCTGGCTTGGAATTCTCGAAGGAATCGGTA TATTGGCTGTGATCACCAATGCATTTGTAATTGCTATTACTTCTGATTACATCCCACGTTTTGTTTATGAATACAAATATGGCCCCTGTG CAAATCATGTAGAACCAAGTGAAAATTGCTTGAAGGGATATGTCAACAATAGCCTATCCTTCTTTGACCTGAGTGAGCTTGGTATGGGAA AATCTGGTTATTGCAGGTACAGAGACTACAGAGGCCCGCCCTGGAGTTCCAAACCCTATGAGTTTACTTTACAATACTGGCATATCCTTG CTGCTAGATTGGCCTTCATTATTGTGTTTGAGCACCTTGTTTTTGGGATTAAGTCATTCATCGCATACCTGATTCCAGACGTACCAAAGG GTCTACATGACCGAATACGACGAGAGAAGTACTTAGTTCAAGAAATGATGTATGAGGCTGAACTGGAACATTTGCAACAACAACGGAGAA AAAGTGGTCAGCCTGTTCACCATGAATGGCCTTAGTTGACACCTGTTACCCATTAGGGGTGATAACATTAATGGGAAGAAATGATGGCAA CTTTGAATGCTAGGTGAAATCTAGGAGGAAGGCATACTTGGCAAACCACATGTATAATATGCTACTTGGAAATGTATCACAGCCATCTCT GGGATTTGAAATATCCAGACTTGTAGGGAAGAAAACAATGACTTGACGACCTTAAAAAGGGTTAGATTGACATTGCAGGAAGCCAGGATG TAATTCTCAGAACCAGTCTCAGGGAGATATATGCTTGGAGAACTCTGCCTTCCATCAACTGCAGTGTAATGGGAAAGAGGGTGGTGAGGT TTTGAAAGACAGATTTCCATGTAAATGTGCACAAGCCAGGCATGGCTTAAAATATCATGCAGTCTTCACTCACATACTAATTTGACTTTG GAAAGTATGGTTGAGTTCAGATACTTATAAGAAATGACTTAAACAAATCCTTGCCTTGGCTGCCAGAACTCTACATCCCTTCAGTTTACA GGTTGGTAGGAATTGCCCATGTCTCTTGCTGAGATTATGGATCTGTGCCACAGGGGATTTATGCTGCTTTACATTGACTATGCAGTTGAA GAGTTGCACATCACCTTTAGTAGTCAAACCAAAAATCTAAGATTCCAAAAAGAACAGCATTCATTGAAATAATATTCCATTGCATTGGCT ACTTCAAGTCTCTTTTACCCCTGGCAGAGCCAGTTGCAGTGCAATTTTTTGTACTAAATGCCAATAAAGCCACATACTTATAAACTATGA ATGGCTATTCTTATATAGTTTAGAACACAACTAATCCATACTTTATTGTGGAAGGCTGTTTTATAGTTTATTTAATTTTTTCTCTATGAT TTATTACAACTCTCACGGAATATTAACTTGAAATGCTGTAAATACGTTGGTTTTCCTTGTCCCTTTGCACCTTGACAGTACGTAGTATAC ATTGTGGTTTATGCAGCTCTGACACCAGTTTTTGCTATTGTAATATGTTTATTCGGGAAAACTGAGGCCAGATGCTCTGCAACACTTACG CTTTTTCAACAATGTGCACTCTTACTCATGAACTAATGAAAATAATGCATGAATATAAATCTATATTATTTGCTAAAAAAAGAAAAAACA TTTGTGTTTTAGTTTCTTTTTTCATGACTGAAGGGAGTTTTATGTTATTATTTCTTCCATAGTTTTGTTTTGGTTTATTTTTAACAACGC TCTAGAAACAAAGTCAAATTAATCACAAAAGACATAATTTTGCTTTGTTGTGGAATTTCTATTTCAACGTCAACTCTGTATCTATGAGTA TGTCTGTTCCACAGACAGATGAGGCAGGAGTGATGGGGCACTCAAGAAAGTTCAGAGGAGGCATAAGCTATGGAGGTTGGAAAGGAAGAA AGAGAAGAGCTGAAGTAAATGTATGGTAGAAATTAAGACGTTTCTTTGCAAAACAAGGAAATCACACATATGCACACATACATATTTATG GTTACTATGATTGTTATTATTTGTCCAATCAAGCAAAGCACCATTATTTCTAACATATAAAAGACCAGATCAAACACAATGGAAATAAAG CTACTACATATATATGCCAGTATTTCTCTAGTAAGATTATGTTTCTCTTACTAGAAAACTATTTTCTAAATATTAACACTGAAAATGTTT TGTTAGCTTTTCCTTCTTTCTCTCCAGAAGAAACATGGATAGATGATAGCTGTTTCATTGTTTGTTTTTGTCAAGCATATTCACTTTCCT CCTTGTCCTCTGATTCTGAGCAAAGGGCCTCAGACTCTGAACTTCCCTCAAGTGCCGTTGTTATGTGAAACTCTTCCATTCAGATTCCAG AGAGGTTCTCATGCTCCCCCCCCTCCTTATTTGTAGCAATCGTAGCAACTAATTCCACTAAGTACAAGGGAGTTTTTTACACTCCTCCAT TTTTATAGCATCTGCATTTCTTTTTCTTTGTTAGGTACATGTATACACCTGCCTGAGTATAAATACTCTCTCTACCTAATAATAACATCA ACCAACATCTTTTCCAAATTAGGGCCACAGAACAGCAACATTTGTCTGACAGTAGTATAAAGAATAATGATAGCTCTATCCTTAAGAAGT ATTTCCTTTCCTTTTTATATAGTCCCGTTAGGGTTTAAAACCATATTGATCAACTAGAAAGAAAAATATGAAAAGAGAAAAATATTTTAA TTTAAAAATTGTAATACATTGATTTATAAAATGCCTTCTCTGATACTTTTGAAACAGATGTGAAAAACAGAAAAAGAAAAAATTGTCTGA AATGTTTATTTTGCAAAACAGTGCAATAGAATCTAGTTATGCCTTCATCACTGTTGACAGTAAATACTGACAGCCCCTTGCAGTGTGTTA GTTTTAGATCACTCTGTTTTAGTTGAGAGAAATGTTTTATATCATGGTTTTTATATGAATACAAATTATTTCTCAAAGATTTATAGCACA CACTATTCTCAGGAATTCTGTATTACATGAATGCTGCTTATATATTTTCATATTCTAACTTGTCTTTTCAAGCAAATAACTAATATATAT GTGCATGCAGTCTGCCTTGACAAGTTGTTCCAAGCTGAAGAGCTTTCACTGTACAATGTGTGGAAAATCACCATAGATCATGGCTGAAAT AGTTTGTAATTGTCTGAGTCTGTGCACGTACTTTTAGATAAAATGCTGCTGAGTGACTGCATGATGAGATACAACTTCTGAATGCTGCAC >In-frame_ENST00000446231_ENST00000256737_TCGA-A2-A0EY_SMG1_chr16_18869491_-_ANO3_chr11_26669255_length(amino acids)=1653AA_start in transcript=203_stop in transcript=5164 MRCGLRRNPERPSSSPALRRLLLLLLLLLLLLLGFLLSPGPERGVGGGRFGRRLALLWAAALGHVVSGKVMSRRAPGSRLSSGGGGGGTK YPRSWNDWQPRTDSASADPDNLKYSSSRDRGGSSSYGLQPSNSAVVSRQRHDDTRVHADIQNDEKGGYSVNGGSGENTYGRKSLGQELRV NNVTSPEFTSVQHGSRALATKDMRKSQERSMSYSDESRLSNLLRRITREDDRDRRLATVKQLKEFIQQPENKLVLVKQLDNILAAVHDVL NESSKLLQELRQEGACCLGLLCASLSYEAEKIFKWIFSKFSSSAKDEVKLLYLCATYKALETVGEKKAFSSVMQLVMTSLQSILENVDTP ELLCKCVKCILLVARCYPHIFSTNFRDTVDILVGWHIDHTQKPSLTQQVSGWLQSLEPFWVADLAFSTTLLGQFLEDMEAYAEDLSHVAS GESVDEDVPPPSVSLPKLAALLRVFSTVVRSIGERFSPIRGPPITEAYVTDVLYRVMRCVTAANQVFFSEAVLTAANECVGVLLGSLDPS MTIHCDMVITYGLDQLENCQTCGTDYIISVLNLLTLIVEQINTKLPSSFVEKLFIPSSKLLFLRYHKEKEVVAVAHAVYQAVLSLKNIPV LETAYKLILGEMTCALNNLLHSLQLPEACSEIKHEAFKNHVFNVDNAKFVVIFDLSALTTIGNAKNSLIGMWALSPTVFALLSKNLMIVH SDLAVHFPAIQYAVLYTLYSHCTRHDHFISSSLSSSSPSLFDGAVISTVTTATKKHFSIILNLLGILLKKDNLNQDTRKLLMTWALEAAV LMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNICLQACSSLHALSSSLPDDLLQRCVDVCRVQLVHSGTRIRQAFGKLLKSIPLDVVL SNNNHTEIQEISLALRSHMSKAPSNTFHPQDFSDVISFILYGNSHRTGKDNWLERLFYSCQRLDKRDQSTIPRNLLKTDAVLWQWAIWEA AQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTADNDEGHGNNQLRLVLLLQYLENLEKLMYNAYEGCANALTSPPK VIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLTEMKTTSLSQGNELEVTIMMVVEALCELHCPEAIQGIAVWSSSIV GKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVDCCISSFDKSVLTLANAGRNSASPKHSLNGESRKTVLSKPTDSSPEVINYLGNKA CECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLKADFNYIKSLSSFESGKFVECTEQLELLPGENINLLAGGSKEKIDMKKLLPNMLSP DPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQSITENVVKYLKQTSRIAIGPLRLSTLTVSQSLPVLSTLQLYCSSALENTVSNRLST EDCLIPLFSEALRSCKQHDVRPWMQALRYTMYQNQLLEKIKGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSE NCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRR -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for SMG1-ANO3 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | SMG1 | chr16:18869491 | chr11:26669255 | ENST00000446231 | - | 29 | 63 | 1_1977 | 1411.3333333333333 | 3662.0 | SMG8 and SMG9 |
| Hgene | SMG1 | chr16:18869492 | chr11:26669256 | ENST00000446231 | - | 29 | 63 | 1_1977 | 1411.3333333333333 | 3662.0 | SMG8 and SMG9 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for SMG1-ANO3 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for SMG1-ANO3 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | ANO3 | C3554374 | DYSTONIA 24 | 3 | GENOMICS_ENGLAND;ORPHANET;UNIPROT |
| Tgene | ANO3 | C0009952 | Febrile Convulsions | 1 | CTD_human |
| Tgene | ANO3 | C0149886 | Seizure, Febrile, Simple | 1 | CTD_human |
| Tgene | ANO3 | C0751057 | Seizure, Febrile, Complex | 1 | CTD_human |
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