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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:SNHG14-GSN (FusionGDB2 ID:83940)

Fusion Gene Summary for SNHG14-GSN

Fusion gene summary

Fusion gene information	Fusion gene name: SNHG14-GSN
	Fusion gene ID: 83940
		Hgene	Tgene
	Gene symbol	SNHG14	GSN
	Gene ID	104472715	2934
	Gene name	small nucleolar RNA host gene 14	gelsolin
	Synonyms	115HG\|IC-SNURF-SNRPN\|LNCAT\|NCRNA00214\|U-UBE3A-ATS\|UBE3A-AS\|UBE3A-AS1\|UBE3A-ATS\|UBE3AATS	ADF\|AGEL
	Cytomap	15q11.2	9q33.2
	Type of gene	ncRNA	protein-coding
	Description	UBE3A antisense RNA 1 (non-protein coding)UBE3A antisense transcriptlarge noncoding antisense transcriptsmall nucleolar RNA host gene 14 (non-protein coding)	gelsolinactin-depolymerizing factorbrevinepididymis secretory sperm binding protein
	Modification date	20200303	20200329
	UniProtAcc	.	P06396
	Ensembl transtripts involved in fusion gene	ENST00000549804, ENST00000547292, ENST00000424208, ENST00000452731, ENST00000554726, ENST00000551631, ENST00000459433, ENST00000551361, ENST00000553134, ENST00000551938, ENST00000384733, ENST00000551077, ENST00000546682, ENST00000553108, ENST00000384430, ENST00000516123, ENST00000553149, ENST00000441592, ENST00000365306, ENST00000414175, ENST00000456576, ENST00000363358, ENST00000424333, ENST00000450809, ENST00000453082, ENST00000365067, ENST00000390982, ENST00000580438,	ENST00000373823, ENST00000373808, ENST00000436847, ENST00000449733, ENST00000412819, ENST00000394353, ENST00000341272, ENST00000545652, ENST00000373818, ENST00000485767, ENST00000373807, ENST00000373806,
Fusion gene scores	* DoF score	24 X 26 X 4=2496	12 X 14 X 2=336
	# samples	27	14
	** MAII score	log2(27/2496*10)=-3.20858662181142 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(14/336*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: SNHG14 [Title/Abstract] AND GSN [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	SNHG14(25227584)-GSN(124094712), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	GSN	GO:0030041	actin filament polymerization	3020431
Tgene	GSN	GO:0051014	actin filament severing	3020431

Fusion gene breakpoints across SNHG14 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across GSN (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	STAD	TCGA-BR-7722-01A	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+

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Fusion Gene ORF analysis for SNHG14-GSN

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
intron-3CDS	ENST00000549804	ENST00000373823	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000549804	ENST00000373808	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000549804	ENST00000436847	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000549804	ENST00000449733	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000549804	ENST00000412819	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000549804	ENST00000394353	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000549804	ENST00000341272	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000549804	ENST00000545652	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000549804	ENST00000373818	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000549804	ENST00000485767	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000549804	ENST00000373807	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000549804	ENST00000373806	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000547292	ENST00000373823	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000547292	ENST00000373808	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000547292	ENST00000436847	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000547292	ENST00000449733	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000547292	ENST00000412819	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000547292	ENST00000394353	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000547292	ENST00000341272	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000547292	ENST00000545652	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000547292	ENST00000373818	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000547292	ENST00000485767	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000547292	ENST00000373807	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000547292	ENST00000373806	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000424208	ENST00000373823	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000424208	ENST00000373808	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000424208	ENST00000436847	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000424208	ENST00000449733	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000424208	ENST00000412819	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000424208	ENST00000394353	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000424208	ENST00000341272	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000424208	ENST00000545652	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000424208	ENST00000373818	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000424208	ENST00000485767	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000424208	ENST00000373807	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000424208	ENST00000373806	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000452731	ENST00000373823	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000452731	ENST00000373808	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000452731	ENST00000436847	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000452731	ENST00000449733	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000452731	ENST00000412819	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000452731	ENST00000394353	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000452731	ENST00000341272	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000452731	ENST00000545652	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000452731	ENST00000373818	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000452731	ENST00000485767	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000452731	ENST00000373807	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000452731	ENST00000373806	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000554726	ENST00000373823	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000554726	ENST00000373808	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000554726	ENST00000436847	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000554726	ENST00000449733	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000554726	ENST00000412819	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000554726	ENST00000394353	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000554726	ENST00000341272	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000554726	ENST00000545652	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000554726	ENST00000373818	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000554726	ENST00000485767	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000554726	ENST00000373807	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000554726	ENST00000373806	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
3UTR-3CDS	ENST00000551631	ENST00000373823	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
3UTR-3CDS	ENST00000551631	ENST00000373808	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
3UTR-3CDS	ENST00000551631	ENST00000436847	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
3UTR-3CDS	ENST00000551631	ENST00000449733	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
3UTR-3CDS	ENST00000551631	ENST00000412819	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
3UTR-3CDS	ENST00000551631	ENST00000394353	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
3UTR-3CDS	ENST00000551631	ENST00000341272	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
3UTR-3CDS	ENST00000551631	ENST00000545652	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
3UTR-3CDS	ENST00000551631	ENST00000373818	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
3UTR-intron	ENST00000551631	ENST00000485767	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
3UTR-intron	ENST00000551631	ENST00000373807	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
3UTR-intron	ENST00000551631	ENST00000373806	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000459433	ENST00000373823	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000459433	ENST00000373808	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000459433	ENST00000436847	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000459433	ENST00000449733	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000459433	ENST00000412819	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000459433	ENST00000394353	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000459433	ENST00000341272	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000459433	ENST00000545652	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000459433	ENST00000373818	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000459433	ENST00000485767	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000459433	ENST00000373807	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000459433	ENST00000373806	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
3UTR-3CDS	ENST00000551361	ENST00000373823	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
3UTR-3CDS	ENST00000551361	ENST00000373808	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
3UTR-3CDS	ENST00000551361	ENST00000436847	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
3UTR-3CDS	ENST00000551361	ENST00000449733	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
3UTR-3CDS	ENST00000551361	ENST00000412819	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
3UTR-3CDS	ENST00000551361	ENST00000394353	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
3UTR-3CDS	ENST00000551361	ENST00000341272	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
3UTR-3CDS	ENST00000551361	ENST00000545652	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
3UTR-3CDS	ENST00000551361	ENST00000373818	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
3UTR-intron	ENST00000551361	ENST00000485767	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
3UTR-intron	ENST00000551361	ENST00000373807	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
3UTR-intron	ENST00000551361	ENST00000373806	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000553134	ENST00000373823	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000553134	ENST00000373808	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000553134	ENST00000436847	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000553134	ENST00000449733	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000553134	ENST00000412819	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000553134	ENST00000394353	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000553134	ENST00000341272	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000553134	ENST00000545652	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000553134	ENST00000373818	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000553134	ENST00000485767	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000553134	ENST00000373807	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000553134	ENST00000373806	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000551938	ENST00000373823	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000551938	ENST00000373808	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000551938	ENST00000436847	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000551938	ENST00000449733	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000551938	ENST00000412819	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000551938	ENST00000394353	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000551938	ENST00000341272	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000551938	ENST00000545652	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000551938	ENST00000373818	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000551938	ENST00000485767	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000551938	ENST00000373807	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000551938	ENST00000373806	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000384733	ENST00000373823	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000384733	ENST00000373808	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000384733	ENST00000436847	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000384733	ENST00000449733	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000384733	ENST00000412819	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000384733	ENST00000394353	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000384733	ENST00000341272	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000384733	ENST00000545652	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000384733	ENST00000373818	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000384733	ENST00000485767	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000384733	ENST00000373807	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000384733	ENST00000373806	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000551077	ENST00000373823	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000551077	ENST00000373808	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000551077	ENST00000436847	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000551077	ENST00000449733	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000551077	ENST00000412819	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000551077	ENST00000394353	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000551077	ENST00000341272	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000551077	ENST00000545652	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000551077	ENST00000373818	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000551077	ENST00000485767	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000551077	ENST00000373807	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000551077	ENST00000373806	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000546682	ENST00000373823	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000546682	ENST00000373808	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000546682	ENST00000436847	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000546682	ENST00000449733	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000546682	ENST00000412819	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000546682	ENST00000394353	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000546682	ENST00000341272	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000546682	ENST00000545652	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000546682	ENST00000373818	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000546682	ENST00000485767	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000546682	ENST00000373807	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000546682	ENST00000373806	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000553108	ENST00000373823	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000553108	ENST00000373808	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000553108	ENST00000436847	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000553108	ENST00000449733	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000553108	ENST00000412819	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000553108	ENST00000394353	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000553108	ENST00000341272	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000553108	ENST00000545652	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000553108	ENST00000373818	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000553108	ENST00000485767	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000553108	ENST00000373807	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000553108	ENST00000373806	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000384430	ENST00000373823	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000384430	ENST00000373808	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000384430	ENST00000436847	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000384430	ENST00000449733	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000384430	ENST00000412819	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000384430	ENST00000394353	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000384430	ENST00000341272	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000384430	ENST00000545652	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000384430	ENST00000373818	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000384430	ENST00000485767	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000384430	ENST00000373807	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000384430	ENST00000373806	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000516123	ENST00000373823	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000516123	ENST00000373808	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000516123	ENST00000436847	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000516123	ENST00000449733	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000516123	ENST00000412819	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000516123	ENST00000394353	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000516123	ENST00000341272	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000516123	ENST00000545652	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000516123	ENST00000373818	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000516123	ENST00000485767	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000516123	ENST00000373807	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000516123	ENST00000373806	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000553149	ENST00000373823	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000553149	ENST00000373808	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000553149	ENST00000436847	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000553149	ENST00000449733	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000553149	ENST00000412819	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000553149	ENST00000394353	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000553149	ENST00000341272	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000553149	ENST00000545652	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000553149	ENST00000373818	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000553149	ENST00000485767	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000553149	ENST00000373807	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000553149	ENST00000373806	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000441592	ENST00000373823	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000441592	ENST00000373808	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000441592	ENST00000436847	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000441592	ENST00000449733	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000441592	ENST00000412819	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000441592	ENST00000394353	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000441592	ENST00000341272	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000441592	ENST00000545652	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000441592	ENST00000373818	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000441592	ENST00000485767	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000441592	ENST00000373807	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000441592	ENST00000373806	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000365306	ENST00000373823	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000365306	ENST00000373808	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000365306	ENST00000436847	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000365306	ENST00000449733	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000365306	ENST00000412819	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000365306	ENST00000394353	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000365306	ENST00000341272	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000365306	ENST00000545652	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000365306	ENST00000373818	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000365306	ENST00000485767	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000365306	ENST00000373807	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000365306	ENST00000373806	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000414175	ENST00000373823	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000414175	ENST00000373808	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000414175	ENST00000436847	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000414175	ENST00000449733	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000414175	ENST00000412819	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000414175	ENST00000394353	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000414175	ENST00000341272	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000414175	ENST00000545652	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000414175	ENST00000373818	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000414175	ENST00000485767	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000414175	ENST00000373807	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000414175	ENST00000373806	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000456576	ENST00000373823	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000456576	ENST00000373808	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000456576	ENST00000436847	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000456576	ENST00000449733	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000456576	ENST00000412819	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000456576	ENST00000394353	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000456576	ENST00000341272	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000456576	ENST00000545652	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000456576	ENST00000373818	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000456576	ENST00000485767	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000456576	ENST00000373807	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000456576	ENST00000373806	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000363358	ENST00000373823	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000363358	ENST00000373808	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000363358	ENST00000436847	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000363358	ENST00000449733	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000363358	ENST00000412819	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000363358	ENST00000394353	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000363358	ENST00000341272	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000363358	ENST00000545652	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000363358	ENST00000373818	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000363358	ENST00000485767	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000363358	ENST00000373807	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000363358	ENST00000373806	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000424333	ENST00000373823	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000424333	ENST00000373808	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000424333	ENST00000436847	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000424333	ENST00000449733	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000424333	ENST00000412819	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000424333	ENST00000394353	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000424333	ENST00000341272	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000424333	ENST00000545652	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000424333	ENST00000373818	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000424333	ENST00000485767	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000424333	ENST00000373807	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000424333	ENST00000373806	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000450809	ENST00000373823	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000450809	ENST00000373808	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000450809	ENST00000436847	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000450809	ENST00000449733	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000450809	ENST00000412819	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000450809	ENST00000394353	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000450809	ENST00000341272	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000450809	ENST00000545652	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000450809	ENST00000373818	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000450809	ENST00000485767	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000450809	ENST00000373807	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000450809	ENST00000373806	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000453082	ENST00000373823	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000453082	ENST00000373808	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000453082	ENST00000436847	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000453082	ENST00000449733	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000453082	ENST00000412819	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000453082	ENST00000394353	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000453082	ENST00000341272	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000453082	ENST00000545652	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000453082	ENST00000373818	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000453082	ENST00000485767	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000453082	ENST00000373807	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000453082	ENST00000373806	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000365067	ENST00000373823	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000365067	ENST00000373808	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000365067	ENST00000436847	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000365067	ENST00000449733	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000365067	ENST00000412819	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000365067	ENST00000394353	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000365067	ENST00000341272	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000365067	ENST00000545652	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000365067	ENST00000373818	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000365067	ENST00000485767	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000365067	ENST00000373807	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000365067	ENST00000373806	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000390982	ENST00000373823	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000390982	ENST00000373808	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000390982	ENST00000436847	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000390982	ENST00000449733	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000390982	ENST00000412819	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000390982	ENST00000394353	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000390982	ENST00000341272	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000390982	ENST00000545652	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000390982	ENST00000373818	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000390982	ENST00000485767	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000390982	ENST00000373807	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000390982	ENST00000373806	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000580438	ENST00000373823	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000580438	ENST00000373808	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000580438	ENST00000436847	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000580438	ENST00000449733	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000580438	ENST00000412819	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000580438	ENST00000394353	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000580438	ENST00000341272	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000580438	ENST00000545652	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-3CDS	ENST00000580438	ENST00000373818	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000580438	ENST00000485767	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000580438	ENST00000373807	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+
intron-intron	ENST00000580438	ENST00000373806	SNHG14	chr15	25227584	+	GSN	chr9	124094712	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

Seq length
(transcript)

BP loci
(transcript)

Predicted start
(transcript)

Predicted stop
(transcript)

Seq length
(amino acids)

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

No-coding score

Coding score

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Fusion Genomic Features for SNHG14-GSN

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
SNHG14	chr15	25227584	+	GSN	chr9	124094711	+	0.000122758	0.9998772
SNHG14	chr15	25227584	+	GSN	chr9	124094711	+	0.000122758	0.9998772

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SNHG14-GSN

Go to
FGviewer for the breakpoints of :-:
.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	GSN P06396
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.	FUNCTION: Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis. {ECO:0000269\|PubMed:20393563}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

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Fusion Gene Sequence for SNHG14-GSN

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for SNHG14-GSN

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for SNHG14-GSN

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner	Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
Tgene	GSN	P06396	DB01593	Zinc		Small molecule	Approved\|Investigational
Tgene	GSN	P06396	DB09130	Copper		Small molecule	Approved\|Investigational
Tgene	GSN	P06396	DB14487	Zinc acetate		Small molecule	Approved\|Investigational

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Related Diseases for SNHG14-GSN

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Tgene	GSN	C1622345	Meretoja syndrome	6	CTD_human;GENOMICS_ENGLAND;UNIPROT
Tgene	GSN	C0936273	Familial Amyloid Polyneuropathy, Type IV	3	ORPHANET
Tgene	GSN	C0001787	Osteoporosis, Age-Related	1	CTD_human
Tgene	GSN	C0002726	Amyloidosis	1	GENOMICS_ENGLAND
Tgene	GSN	C0018800	Cardiomegaly	1	CTD_human
Tgene	GSN	C0019193	Hepatitis, Toxic	1	CTD_human
Tgene	GSN	C0023893	Liver Cirrhosis, Experimental	1	CTD_human
Tgene	GSN	C0025500	Mesothelioma	1	CTD_human
Tgene	GSN	C0029456	Osteoporosis	1	CTD_human
Tgene	GSN	C0029459	Osteoporosis, Senile	1	CTD_human
Tgene	GSN	C0030524	Paratuberculosis	1	CTD_human
Tgene	GSN	C0036341	Schizophrenia	1	PSYGENET
Tgene	GSN	C0043094	Weight Gain	1	CTD_human
Tgene	GSN	C0268389	Amyloidosis, familial visceral	1	GENOMICS_ENGLAND
Tgene	GSN	C0751406	Post-Traumatic Osteoporosis	1	CTD_human
Tgene	GSN	C0860207	Drug-Induced Liver Disease	1	CTD_human
Tgene	GSN	C0948089	Acute Coronary Syndrome	1	CTD_human
Tgene	GSN	C1262760	Hepatitis, Drug-Induced	1	CTD_human
Tgene	GSN	C1383860	Cardiac Hypertrophy	1	CTD_human
Tgene	GSN	C3658290	Drug-Induced Acute Liver Injury	1	CTD_human
Tgene	GSN	C4277682	Chemical and Drug Induced Liver Injury	1	CTD_human
Tgene	GSN	C4279912	Chemically-Induced Liver Toxicity	1	CTD_human