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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SOD2-CHMP1A (FusionGDB2 ID:84531)

Fusion Gene Summary for SOD2-CHMP1A

check button Fusion gene summary
Fusion gene informationFusion gene name: SOD2-CHMP1A
Fusion gene ID: 84531
HgeneTgene
Gene symbol

SOD2

CHMP1A

Gene ID

100129518

5119

Gene nameSOD2 overlapping transcript 1charged multivesicular body protein 1A
SynonymsSOD2CHMP1|PCH8|PCOLN3|PRSM1|VPS46-1|VPS46A
Cytomap

6q25.3

16q24.3

Type of genencRNAprotein-coding
DescriptionSuperoxide dismutase [Mn], mitochondrialcharged multivesicular body protein 1acharged multivesicular body protein 1/chromatin modifying protein 1chromatin modifying protein 1Aprocollagen (type III) N-endopeptidaseprotease, metallo, 1, 33kDvacuolar protein sorting-associated protein 46-1
Modification date2020031320200313
UniProtAcc.

Q9HD42

Ensembl transtripts involved in fusion geneENST00000546087, ENST00000538183, 
ENST00000367055, ENST00000367054, 
ENST00000444946, ENST00000337404, 
ENST00000452684, ENST00000535372, 
ENST00000397901, ENST00000253475, 
ENST00000535997, ENST00000550102, 
ENST00000547614, 
Fusion gene scores* DoF score11 X 13 X 4=57245 X 11 X 21=10395
# samples 1648
** MAII scorelog2(16/572*10)=-1.83794324189103
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(48/10395*10)=-4.43671154213721
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SOD2 [Title/Abstract] AND CHMP1A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSOD2(160113693)-CHMP1A(89713739), # samples:1
Anticipated loss of major functional domain due to fusion event.SOD2-CHMP1A seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneCHMP1A

GO:0007076

mitotic chromosome condensation

11559747

TgeneCHMP1A

GO:0016192

vesicle-mediated transport

11559748

TgeneCHMP1A

GO:0016458

gene silencing

11559747

TgeneCHMP1A

GO:0045892

negative regulation of transcription, DNA-templated

11559747


check buttonFusion gene breakpoints across SOD2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across CHMP1A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4CESCTCGA-VS-A953-01ASOD2chr6

160113693

-CHMP1Achr16

89713739

-


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Fusion Gene ORF analysis for SOD2-CHMP1A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000546087ENST00000397901SOD2chr6

160113693

-CHMP1Achr16

89713739

-
Frame-shiftENST00000546087ENST00000253475SOD2chr6

160113693

-CHMP1Achr16

89713739

-
Frame-shiftENST00000546087ENST00000535997SOD2chr6

160113693

-CHMP1Achr16

89713739

-
Frame-shiftENST00000546087ENST00000550102SOD2chr6

160113693

-CHMP1Achr16

89713739

-
5CDS-5UTRENST00000546087ENST00000547614SOD2chr6

160113693

-CHMP1Achr16

89713739

-
Frame-shiftENST00000538183ENST00000397901SOD2chr6

160113693

-CHMP1Achr16

89713739

-
In-frameENST00000538183ENST00000253475SOD2chr6

160113693

-CHMP1Achr16

89713739

-
Frame-shiftENST00000538183ENST00000535997SOD2chr6

160113693

-CHMP1Achr16

89713739

-
Frame-shiftENST00000538183ENST00000550102SOD2chr6

160113693

-CHMP1Achr16

89713739

-
5CDS-5UTRENST00000538183ENST00000547614SOD2chr6

160113693

-CHMP1Achr16

89713739

-
In-frameENST00000367055ENST00000397901SOD2chr6

160113693

-CHMP1Achr16

89713739

-
Frame-shiftENST00000367055ENST00000253475SOD2chr6

160113693

-CHMP1Achr16

89713739

-
In-frameENST00000367055ENST00000535997SOD2chr6

160113693

-CHMP1Achr16

89713739

-
In-frameENST00000367055ENST00000550102SOD2chr6

160113693

-CHMP1Achr16

89713739

-
5CDS-5UTRENST00000367055ENST00000547614SOD2chr6

160113693

-CHMP1Achr16

89713739

-
In-frameENST00000367054ENST00000397901SOD2chr6

160113693

-CHMP1Achr16

89713739

-
Frame-shiftENST00000367054ENST00000253475SOD2chr6

160113693

-CHMP1Achr16

89713739

-
In-frameENST00000367054ENST00000535997SOD2chr6

160113693

-CHMP1Achr16

89713739

-
In-frameENST00000367054ENST00000550102SOD2chr6

160113693

-CHMP1Achr16

89713739

-
5CDS-5UTRENST00000367054ENST00000547614SOD2chr6

160113693

-CHMP1Achr16

89713739

-
Frame-shiftENST00000444946ENST00000397901SOD2chr6

160113693

-CHMP1Achr16

89713739

-
In-frameENST00000444946ENST00000253475SOD2chr6

160113693

-CHMP1Achr16

89713739

-
Frame-shiftENST00000444946ENST00000535997SOD2chr6

160113693

-CHMP1Achr16

89713739

-
Frame-shiftENST00000444946ENST00000550102SOD2chr6

160113693

-CHMP1Achr16

89713739

-
5CDS-5UTRENST00000444946ENST00000547614SOD2chr6

160113693

-CHMP1Achr16

89713739

-
Frame-shiftENST00000337404ENST00000397901SOD2chr6

160113693

-CHMP1Achr16

89713739

-
In-frameENST00000337404ENST00000253475SOD2chr6

160113693

-CHMP1Achr16

89713739

-
Frame-shiftENST00000337404ENST00000535997SOD2chr6

160113693

-CHMP1Achr16

89713739

-
Frame-shiftENST00000337404ENST00000550102SOD2chr6

160113693

-CHMP1Achr16

89713739

-
5CDS-5UTRENST00000337404ENST00000547614SOD2chr6

160113693

-CHMP1Achr16

89713739

-
intron-3CDSENST00000452684ENST00000397901SOD2chr6

160113693

-CHMP1Achr16

89713739

-
intron-3CDSENST00000452684ENST00000253475SOD2chr6

160113693

-CHMP1Achr16

89713739

-
intron-3CDSENST00000452684ENST00000535997SOD2chr6

160113693

-CHMP1Achr16

89713739

-
intron-3CDSENST00000452684ENST00000550102SOD2chr6

160113693

-CHMP1Achr16

89713739

-
intron-5UTRENST00000452684ENST00000547614SOD2chr6

160113693

-CHMP1Achr16

89713739

-
intron-3CDSENST00000535372ENST00000397901SOD2chr6

160113693

-CHMP1Achr16

89713739

-
intron-3CDSENST00000535372ENST00000253475SOD2chr6

160113693

-CHMP1Achr16

89713739

-
intron-3CDSENST00000535372ENST00000535997SOD2chr6

160113693

-CHMP1Achr16

89713739

-
intron-3CDSENST00000535372ENST00000550102SOD2chr6

160113693

-CHMP1Achr16

89713739

-
intron-5UTRENST00000535372ENST00000547614SOD2chr6

160113693

-CHMP1Achr16

89713739

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000538183SOD2chr6160113693-ENST00000253475CHMP1Achr1689713739-235438795877260
ENST00000367055SOD2chr6160113693-ENST00000397901CHMP1Achr1689713739-22672931783260
ENST00000367055SOD2chr6160113693-ENST00000535997CHMP1Achr1689713739-22352931783260
ENST00000367055SOD2chr6160113693-ENST00000550102CHMP1Achr1689713739-8092931783260
ENST00000367054SOD2chr6160113693-ENST00000397901CHMP1Achr1689713739-226128761777238
ENST00000367054SOD2chr6160113693-ENST00000535997CHMP1Achr1689713739-222928761777238
ENST00000367054SOD2chr6160113693-ENST00000550102CHMP1Achr1689713739-80328761777238
ENST00000444946SOD2chr6160113693-ENST00000253475CHMP1Achr1689713739-22673008790260
ENST00000337404SOD2chr6160113693-ENST00000253475CHMP1Achr1689713739-230433745827260

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000538183ENST00000253475SOD2chr6160113693-CHMP1Achr1689713739-0.204733220.7952668
ENST00000367055ENST00000397901SOD2chr6160113693-CHMP1Achr1689713739-0.196696420.80330354
ENST00000367055ENST00000535997SOD2chr6160113693-CHMP1Achr1689713739-0.186858730.8131413
ENST00000367055ENST00000550102SOD2chr6160113693-CHMP1Achr1689713739-0.00896510.9910349
ENST00000367054ENST00000397901SOD2chr6160113693-CHMP1Achr1689713739-0.185586540.8144135
ENST00000367054ENST00000535997SOD2chr6160113693-CHMP1Achr1689713739-0.174826730.8251733
ENST00000367054ENST00000550102SOD2chr6160113693-CHMP1Achr1689713739-0.0081613540.99183863
ENST00000444946ENST00000253475SOD2chr6160113693-CHMP1Achr1689713739-0.210094880.7899051
ENST00000337404ENST00000253475SOD2chr6160113693-CHMP1Achr1689713739-0.22316940.77683055

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Fusion Genomic Features for SOD2-CHMP1A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SOD2-CHMP1A


check button Go to

FGviewer for the breakpoints of chr6:160113693-chr16:89713739

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CHMP1A

Q9HD42

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in cytokinesis. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells. May also be involved in chromosome condensation. Targets the Polycomb group (PcG) protein BMI1/PCGF4 to regions of condensed chromatin. May play a role in stable cell cycle progression and in PcG gene silencing. {ECO:0000269|PubMed:11559747, ECO:0000269|PubMed:11559748, ECO:0000269|PubMed:19129479, ECO:0000269|PubMed:23045692}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCHMP1Achr6:160113693chr16:89713739ENST0000039790137102_12484.0197.0Coiled coilOntology_term=ECO:0000255
TgeneCHMP1Achr6:160113693chr16:89713739ENST0000039790137185_19584.0197.0MotifNote=MIT-interacting motif

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCHMP1Achr6:160113693chr16:89713739ENST00000397901375_4784.0197.0Coiled coilOntology_term=ECO:0000255


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Fusion Gene Sequence for SOD2-CHMP1A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000538183_ENST00000253475_TCGA-VS-A953-01A_SOD2_chr6_160113693_-_CHMP1A_chr16_89713739_length(transcript)=2354nt_BP=387nt
CGGGGCGGCGGTGCCCTTGCGGCGCAGCTGGGGTCGCGGCCCTGCTCCCCGCGCTTTCTTAAGGCCCGCGGGCGGCGCAGGAGCGGCACT
CGTGGCTGTGGTGGCTTCGGCAGCGGCTTCAGCAGATCGGCGGCATCAGCGGTAGCACCAGCACTAGCAGCATGTTGAGCCGGGCAGTGT
GCGGCACCAGCAGGCAGCTGGCTCCGGTTTTGGGGTATCTGGGCTCCAGGCAGAAGCACAGCCTCCCCGACCTGCCCTACGACTACGGCG
CCCTGGAACCTCACATCAACGCGCAGATCATGCAGCTGCACCACAGCAAGCACCACGCGGCCTACGTGAACAACCTGAACGTCACCGAGG
AGAAGTACCAGGAGGCGTTGGCCAAGGGTGACCAAGAATATGGCCCAGGTGACCAAAGCCCTGGACAAGGCCCTGAGCACCATGGACCTG
CAGAAGGTCTCCTCAGTGATGGACAGGTTCGAGCAGCAGGTGCAGAACCTGGACGTCCATACATCGGTGATGGAGGACTCCATGAGCTCG
GCCACCACCCTGACCACGCCGCAGGAGCAGGTGGACAGCCTCATCATGCAGATCGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAGCTC
AGCCAGCTGCCCGAGGGCGCCTCTGCCGTGGGCGAGAGCTCTGTGCGCAGCCAGGAGGACCAGCTGTCACGGAGGTTGGCCGCCTTGAGG
AACTAGCCGTGCCCCGCCGGTGTGCACCGCCTCTGCCCCGTGATGTGCTGGAAGGCTCCTGTCCTCTCCCCACCGCGTCTTGCCTTTGTG
CTGACCCCGCGGGGCTGCGGCCGGCAGCCACTCTGCGTCTCTCACCTGCCAGGCCTGCGTGGCCTTAGGGTTGTTCCTGTTCTTTTAGGT
TGGGCGGTGGGTCTGTGTCCTGGTGTTGAGTTTCTGCAAATTTCTGGGGGTGATTTCTGTGACTCTGGGCCCACAGCGGGGAGGCCAAGA
GGGGCCCTGTGGACTTTCACCCAGCACTGTGGGGGCCTTCAGACTCTGGGGCAGCAGACATGCTGCTTCCCATCAGCCAGAGGGGGTCAG
GGCTGCCCTGTTGCCAAACAACTCCCTGAGGCCTCTCCGCACCACCTCAGCGGGCAGGAGGTCCCACCATGTGGACAGACATAGCCCAAG
GAGGCACCACAGGTCTATGTGTGCTGGGGGATGTCAGGTGCCACCCAACGCTGTCCTGGTGGTATTTACAATGACATCCTCCTCCTCCAT
CACTCCAGGGGTGGTGTCTCGGCCGCCCCTACCAGCTGGCTGAGCCCCCTGGCCTCCTGCGCTCCCTCACTTCCCTCAGTTCCCAAAGCT
GCCCAGTCCATGGGGACAGAACCGTCACTCAGATCCACATTCAAGTGTGCCCACCCTGCAGTCTTCATCCTCACTCAGCTGCTGCCTCTG
GAGGTGCCTTTGGCCACATGTGCTGTGCTGTTTGTCTCCTCGACAGGGAGCCTGTCCACCAGCAGGCTGCGGTCCCAGCGGGTGCGTCTG
CAGCTCCTCCCCTTGGGCAGCCTGGTTCTCCCGGAGGACCTTTCCTTGGGGCCCTGCTTCATGACGATGCTGCCTGTGTCACCCTCTACC
ATCTGTAAACAACTGGGTGCCTTCCCCGACCACACCCCAATGCCTTCCCAGCTTGGAAGCCAAGGCAGCTGATGAAGGGAGCTCAGGAGA
GCCGTCTTCAGCTGGGCTGGGGTTGGGGCTGCTGTGAGGAAAACCTGCCATTGTGGCCCTGGAGAGTCACCAGCAGCTCTTGGGAAGGAC
TTGCTGGGAGGCTGAGAGAGGCTTTGGGCACAGCCTGCTGTCTTTTCCATTTCCTAAAGTTTACTTCATTGTCTTGAGGCTTCCAGGTTT
TGTTTTTGTTTTTGCCAAAGTAGAAAAGGCAGGTGGTGGGCGGCTGGCAGGGAGTGCGGGTCCCCGCCCCTCTTCAGTCCTGCCCTCCCC
TCCTCAGTCCTGCCCACCCCGTGCAGCCCATGCTGAGGCTGCAGTGGTGTCGTGGGTGTTACGTGCAGGAACGTGGAGACCCTGACGTGG
GCTCACTGCGTTTGGTTTTCTTTTCAGAACTTGGGAGCCCCCAGGGAGGGGCTAGTGTTGGTAGGTCCTAGACGTGGTTCCCTCCAGCCT
CCCCAAAATCAACCCTGGTGTTGAGAGAACGTCCTTCTGTCCATCGTGGGTAACAGCCTTGGGGAGGGTGCAGAGCTCTGCAGAGCCATG
GGCCAGGTGGGGCTGCCTCAGTCCTGTCCCCTTGGGCACTGAGGAGAGGGGCCCATTCACCTTTCTCCTAGAATGCTGTTGTAAATAAAC

>In-frame_ENST00000538183_ENST00000253475_TCGA-VS-A953-01A_SOD2_chr6_160113693_-_CHMP1A_chr16_89713739_length(amino acids)=260AA_start in transcript=95_stop in transcript=877
MWWLRQRLQQIGGISGSTSTSSMLSRAVCGTSRQLAPVLGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVTEEK
YQEALAKGDQEYGPGDQSPGQGPEHHGPAEGLLSDGQVRAAGAEPGRPYIGDGGLHELGHHPDHAAGAGGQPHHADRRGEWPGGAGPAQP

--------------------------------------------------------------
>In-frame_ENST00000367055_ENST00000397901_TCGA-VS-A953-01A_SOD2_chr6_160113693_-_CHMP1A_chr16_89713739_length(transcript)=2267nt_BP=293nt
GCTGTGGTGGCTTCGGCAGCGGCTTCAGCAGATCGGCGGCATCAGCGGTAGCACCAGCACTAGCAGCATGTTGAGCCGGGCAGTGTGCGG
CACCAGCAGGCAGCTGGCTCCGGTTTTGGGGTATCTGGGCTCCAGGCAGAAGCACAGCCTCCCCGACCTGCCCTACGACTACGGCGCCCT
GGAACCTCACATCAACGCGCAGATCATGCAGCTGCACCACAGCAAGCACCACGCGGCCTACGTGAACAACCTGAACGTCACCGAGGAGAA
GTACCAGGAGGCGTTGGCCAAGGGTGACCAAGAATATGGCCCAGGTGACCAAAGCCCTGGACAAGGCCCTGAGCACCATGGACCTGCAGA
AGGTCTCCTCAGTGATGGACAGGTTCGAGCAGCAGGTGCAGAACCTGGACGTCCATACATCGGTGATGGAGGACTCCATGAGCTCGGCCA
CCACCCTGACCACGCCGCAGGAGCAGGTGGACAGCCTCATCATGCAGATCGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAGCTCAGCC
AGCTGCCCGAGGGCGCCTCTGCCGTGGGCGAGAGCTCTGTGCGCAGCCAGGAGGACCAGCTGTCACGGAGGTTGGCCGCCTTGAGGAACT
AGCCGTGCCCCGCCGGTGTGCACCGCCTCTGCCCCGTGATGTGCTGGAAGGCTCCTGTCCTCTCCCCACCGCGTCTTGCCTTTGTGCTGA
CCCCGCGGGGCTGCGGCCGGCAGCCACTCTGCGTCTCTCACCTGCCAGGCCTGCGTGGCCTTAGGGTTGTTCCTGTTCTTTTAGGTTGGG
CGGTGGGTCTGTGTCCTGGTGTTGAGTTTCTGCAAATTTCTGGGGGTGATTTCTGTGACTCTGGGCCCACAGCGGGGAGGCCAAGAGGGG
CCCTGTGGACTTTCACCCAGCACTGTGGGGGCCTTCAGACTCTGGGGCAGCAGACATGCTGCTTCCCATCAGCCAGAGGGGGTCAGGGCT
GCCCTGTTGCCAAACAACTCCCTGAGGCCTCTCCGCACCACCTCAGCGGGCAGGAGGTCCCACCATGTGGACAGACATAGCCCAAGGAGG
CACCACAGGTCTATGTGTGCTGGGGGATGTCAGGTGCCACCCAACGCTGTCCTGGTGGTATTTACAATGACATCCTCCTCCTCCATCACT
CCAGGGGTGGTGTCTCGGCCGCCCCTACCAGCTGGCTGAGCCCCCTGGCCTCCTGCGCTCCCTCACTTCCCTCAGTTCCCAAAGCTGCCC
AGTCCATGGGGACAGAACCGTCACTCAGATCCACATTCAAGTGTGCCCACCCTGCAGTCTTCATCCTCACTCAGCTGCTGCCTCTGGAGG
TGCCTTTGGCCACATGTGCTGTGCTGTTTGTCTCCTCGACAGGGAGCCTGTCCACCAGCAGGCTGCGGTCCCAGCGGGTGCGTCTGCAGC
TCCTCCCCTTGGGCAGCCTGGTTCTCCCGGAGGACCTTTCCTTGGGGCCCTGCTTCATGACGATGCTGCCTGTGTCACCCTCTACCATCT
GTAAACAACTGGGTGCCTTCCCCGACCACACCCCAATGCCTTCCCAGCTTGGAAGCCAAGGCAGCTGATGAAGGGAGCTCAGGAGAGCCG
TCTTCAGCTGGGCTGGGGTTGGGGCTGCTGTGAGGAAAACCTGCCATTGTGGCCCTGGAGAGTCACCAGCAGCTCTTGGGAAGGACTTGC
TGGGAGGCTGAGAGAGGCTTTGGGCACAGCCTGCTGTCTTTTCCATTTCCTAAAGTTTACTTCATTGTCTTGAGGCTTCCAGGTTTTGTT
TTTGTTTTTGCCAAAGTAGAAAAGGCAGGTGGTGGGCGGCTGGCAGGGAGTGCGGGTCCCCGCCCCTCTTCAGTCCTGCCCTCCCCTCCT
CAGTCCTGCCCACCCCGTGCAGCCCATGCTGAGGCTGCAGTGGTGTCGTGGGTGTTACGTGCAGGAACGTGGAGACCCTGACGTGGGCTC
ACTGCGTTTGGTTTTCTTTTCAGAACTTGGGAGCCCCCAGGGAGGGGCTAGTGTTGGTAGGTCCTAGACGTGGTTCCCTCCAGCCTCCCC
AAAATCAACCCTGGTGTTGAGAGAACGTCCTTCTGTCCATCGTGGGTAACAGCCTTGGGGAGGGTGCAGAGCTCTGCAGAGCCATGGGCC
AGGTGGGGCTGCCTCAGTCCTGTCCCCTTGGGCACTGAGGAGAGGGGCCCATTCACCTTTCTCCTAGAATGCTGTTGTAAATAAACAAAT

>In-frame_ENST00000367055_ENST00000397901_TCGA-VS-A953-01A_SOD2_chr6_160113693_-_CHMP1A_chr16_89713739_length(amino acids)=260AA_start in transcript=1_stop in transcript=783
LWWLRQRLQQIGGISGSTSTSSMLSRAVCGTSRQLAPVLGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVTEEK
YQEALAKGDQEYGPGDQSPGQGPEHHGPAEGLLSDGQVRAAGAEPGRPYIGDGGLHELGHHPDHAAGAGGQPHHADRRGEWPGGAGPAQP

--------------------------------------------------------------
>In-frame_ENST00000367055_ENST00000535997_TCGA-VS-A953-01A_SOD2_chr6_160113693_-_CHMP1A_chr16_89713739_length(transcript)=2235nt_BP=293nt
GCTGTGGTGGCTTCGGCAGCGGCTTCAGCAGATCGGCGGCATCAGCGGTAGCACCAGCACTAGCAGCATGTTGAGCCGGGCAGTGTGCGG
CACCAGCAGGCAGCTGGCTCCGGTTTTGGGGTATCTGGGCTCCAGGCAGAAGCACAGCCTCCCCGACCTGCCCTACGACTACGGCGCCCT
GGAACCTCACATCAACGCGCAGATCATGCAGCTGCACCACAGCAAGCACCACGCGGCCTACGTGAACAACCTGAACGTCACCGAGGAGAA
GTACCAGGAGGCGTTGGCCAAGGGTGACCAAGAATATGGCCCAGGTGACCAAAGCCCTGGACAAGGCCCTGAGCACCATGGACCTGCAGA
AGGTCTCCTCAGTGATGGACAGGTTCGAGCAGCAGGTGCAGAACCTGGACGTCCATACATCGGTGATGGAGGACTCCATGAGCTCGGCCA
CCACCCTGACCACGCCGCAGGAGCAGGTGGACAGCCTCATCATGCAGATCGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAGCTCAGCC
AGCTGCCCGAGGGCGCCTCTGCCGTGGGCGAGAGCTCTGTGCGCAGCCAGGAGGACCAGCTGTCACGGAGGTTGGCCGCCTTGAGGAACT
AGCCGTGCCCCGCCGGTGTGCACCGCCTCTGCCCCGTGATGTGCTGGAAGGCTCCTGTCCTCTCCCCACCGCGTCTTGCCTTTGTGCTGA
CCCCGCGGGGCTGCGGCCGGCAGCCACTCTGCGTCTCTCACCTGCCAGGCCTGCGTGGCCTTAGGGTTGTTCCTGTTCTTTTAGGTTGGG
CGGTGGGTCTGTGTCCTGGTGTTGAGTTTCTGCAAATTTCTGGGGGTGATTTCTGTGACTCTGGGCCCACAGCGGGGAGGCCAAGAGGGG
CCCTGTGGACTTTCACCCAGCACTGTGGGGGCCTTCAGACTCTGGGGCAGCAGACATGCTGCTTCCCATCAGCCAGAGGGGGTCAGGGCT
GCCCTGTTGCCAAACAACTCCCTGAGGCCTCTCCGCACCACCTCAGCGGGCAGGAGGTCCCACCATGTGGACAGACATAGCCCAAGGAGG
CACCACAGGTCTATGTGTGCTGGGGGATGTCAGGTGCCACCCAACGCTGTCCTGGTGGTATTTACAATGACATCCTCCTCCTCCATCACT
CCAGGGGTGGTGTCTCGGCCGCCCCTACCAGCTGGCTGAGCCCCCTGGCCTCCTGCGCTCCCTCACTTCCCTCAGTTCCCAAAGCTGCCC
AGTCCATGGGGACAGAACCGTCACTCAGATCCACATTCAAGTGTGCCCACCCTGCAGTCTTCATCCTCACTCAGCTGCTGCCTCTGGAGG
TGCCTTTGGCCACATGTGCTGTGCTGTTTGTCTCCTCGACAGGGAGCCTGTCCACCAGCAGGCTGCGGTCCCAGCGGGTGCGTCTGCAGC
TCCTCCCCTTGGGCAGCCTGGTTCTCCCGGAGGACCTTTCCTTGGGGCCCTGCTTCATGACGATGCTGCCTGTGTCACCCTCTACCATCT
GTAAACAACTGGGTGCCTTCCCCGACCACACCCCAATGCCTTCCCAGCTTGGAAGCCAAGGCAGCTGATGAAGGGAGCTCAGGAGAGCCG
TCTTCAGCTGGGCTGGGGTTGGGGCTGCTGTGAGGAAAACCTGCCATTGTGGCCCTGGAGAGTCACCAGCAGCTCTTGGGAAGGACTTGC
TGGGAGGCTGAGAGAGGCTTTGGGCACAGCCTGCTGTCTTTTCCATTTCCTAAAGTTTACTTCATTGTCTTGAGGCTTCCAGGTTTTGTT
TTTGTTTTTGCCAAAGTAGAAAAGGCAGGTGGTGGGCGGCTGGCAGGGAGTGCGGGTCCCCGCCCCTCTTCAGTCCTGCCCTCCCCTCCT
CAGTCCTGCCCACCCCGTGCAGCCCATGCTGAGGCTGCAGTGGTGTCGTGGGTGTTACGTGCAGGAACGTGGAGACCCTGACGTGGGCTC
ACTGCGTTTGGTTTTCTTTTCAGAACTTGGGAGCCCCCAGGGAGGGGCTAGTGTTGGTAGGTCCTAGACGTGGTTCCCTCCAGCCTCCCC
AAAATCAACCCTGGTGTTGAGAGAACGTCCTTCTGTCCATCGTGGGTAACAGCCTTGGGGAGGGTGCAGAGCTCTGCAGAGCCATGGGCC

>In-frame_ENST00000367055_ENST00000535997_TCGA-VS-A953-01A_SOD2_chr6_160113693_-_CHMP1A_chr16_89713739_length(amino acids)=260AA_start in transcript=1_stop in transcript=783
LWWLRQRLQQIGGISGSTSTSSMLSRAVCGTSRQLAPVLGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVTEEK
YQEALAKGDQEYGPGDQSPGQGPEHHGPAEGLLSDGQVRAAGAEPGRPYIGDGGLHELGHHPDHAAGAGGQPHHADRRGEWPGGAGPAQP

--------------------------------------------------------------
>In-frame_ENST00000367055_ENST00000550102_TCGA-VS-A953-01A_SOD2_chr6_160113693_-_CHMP1A_chr16_89713739_length(transcript)=809nt_BP=293nt
GCTGTGGTGGCTTCGGCAGCGGCTTCAGCAGATCGGCGGCATCAGCGGTAGCACCAGCACTAGCAGCATGTTGAGCCGGGCAGTGTGCGG
CACCAGCAGGCAGCTGGCTCCGGTTTTGGGGTATCTGGGCTCCAGGCAGAAGCACAGCCTCCCCGACCTGCCCTACGACTACGGCGCCCT
GGAACCTCACATCAACGCGCAGATCATGCAGCTGCACCACAGCAAGCACCACGCGGCCTACGTGAACAACCTGAACGTCACCGAGGAGAA
GTACCAGGAGGCGTTGGCCAAGGGTGACCAAGAATATGGCCCAGGTGACCAAAGCCCTGGACAAGGCCCTGAGCACCATGGACCTGCAGA
AGGTCTCCTCAGTGATGGACAGGTTCGAGCAGCAGGTGCAGAACCTGGACGTCCATACATCGGTGATGGAGGACTCCATGAGCTCGGCCA
CCACCCTGACCACGCCGCAGGAGCAGGTGGACAGCCTCATCATGCAGATCGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAGCTCAGCC
AGCTGCCCGAGGGCGCCTCTGCCGTGGGCGAGAGCTCTGTGCGCAGCCAGGAGGACCAGCTGTCACGGAGGTTGGCCGCCTTGAGGAACT
AGCCGTGCCCCGCCGGTGTGCACCGCCTCTGCCCCGTGATGTGCTGGAAGGCTCCTGTCCTCTCCCCACCGCGTCTTGCCTTTGTGCTGA

>In-frame_ENST00000367055_ENST00000550102_TCGA-VS-A953-01A_SOD2_chr6_160113693_-_CHMP1A_chr16_89713739_length(amino acids)=260AA_start in transcript=1_stop in transcript=783
LWWLRQRLQQIGGISGSTSTSSMLSRAVCGTSRQLAPVLGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVTEEK
YQEALAKGDQEYGPGDQSPGQGPEHHGPAEGLLSDGQVRAAGAEPGRPYIGDGGLHELGHHPDHAAGAGGQPHHADRRGEWPGGAGPAQP

--------------------------------------------------------------
>In-frame_ENST00000367054_ENST00000397901_TCGA-VS-A953-01A_SOD2_chr6_160113693_-_CHMP1A_chr16_89713739_length(transcript)=2261nt_BP=287nt
GTGGCTTCGGCAGCGGCTTCAGCAGATCGGCGGCATCAGCGGTAGCACCAGCACTAGCAGCATGTTGAGCCGGGCAGTGTGCGGCACCAG
CAGGCAGCTGGCTCCGGTTTTGGGGTATCTGGGCTCCAGGCAGAAGCACAGCCTCCCCGACCTGCCCTACGACTACGGCGCCCTGGAACC
TCACATCAACGCGCAGATCATGCAGCTGCACCACAGCAAGCACCACGCGGCCTACGTGAACAACCTGAACGTCACCGAGGAGAAGTACCA
GGAGGCGTTGGCCAAGGGTGACCAAGAATATGGCCCAGGTGACCAAAGCCCTGGACAAGGCCCTGAGCACCATGGACCTGCAGAAGGTCT
CCTCAGTGATGGACAGGTTCGAGCAGCAGGTGCAGAACCTGGACGTCCATACATCGGTGATGGAGGACTCCATGAGCTCGGCCACCACCC
TGACCACGCCGCAGGAGCAGGTGGACAGCCTCATCATGCAGATCGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAGCTCAGCCAGCTGC
CCGAGGGCGCCTCTGCCGTGGGCGAGAGCTCTGTGCGCAGCCAGGAGGACCAGCTGTCACGGAGGTTGGCCGCCTTGAGGAACTAGCCGT
GCCCCGCCGGTGTGCACCGCCTCTGCCCCGTGATGTGCTGGAAGGCTCCTGTCCTCTCCCCACCGCGTCTTGCCTTTGTGCTGACCCCGC
GGGGCTGCGGCCGGCAGCCACTCTGCGTCTCTCACCTGCCAGGCCTGCGTGGCCTTAGGGTTGTTCCTGTTCTTTTAGGTTGGGCGGTGG
GTCTGTGTCCTGGTGTTGAGTTTCTGCAAATTTCTGGGGGTGATTTCTGTGACTCTGGGCCCACAGCGGGGAGGCCAAGAGGGGCCCTGT
GGACTTTCACCCAGCACTGTGGGGGCCTTCAGACTCTGGGGCAGCAGACATGCTGCTTCCCATCAGCCAGAGGGGGTCAGGGCTGCCCTG
TTGCCAAACAACTCCCTGAGGCCTCTCCGCACCACCTCAGCGGGCAGGAGGTCCCACCATGTGGACAGACATAGCCCAAGGAGGCACCAC
AGGTCTATGTGTGCTGGGGGATGTCAGGTGCCACCCAACGCTGTCCTGGTGGTATTTACAATGACATCCTCCTCCTCCATCACTCCAGGG
GTGGTGTCTCGGCCGCCCCTACCAGCTGGCTGAGCCCCCTGGCCTCCTGCGCTCCCTCACTTCCCTCAGTTCCCAAAGCTGCCCAGTCCA
TGGGGACAGAACCGTCACTCAGATCCACATTCAAGTGTGCCCACCCTGCAGTCTTCATCCTCACTCAGCTGCTGCCTCTGGAGGTGCCTT
TGGCCACATGTGCTGTGCTGTTTGTCTCCTCGACAGGGAGCCTGTCCACCAGCAGGCTGCGGTCCCAGCGGGTGCGTCTGCAGCTCCTCC
CCTTGGGCAGCCTGGTTCTCCCGGAGGACCTTTCCTTGGGGCCCTGCTTCATGACGATGCTGCCTGTGTCACCCTCTACCATCTGTAAAC
AACTGGGTGCCTTCCCCGACCACACCCCAATGCCTTCCCAGCTTGGAAGCCAAGGCAGCTGATGAAGGGAGCTCAGGAGAGCCGTCTTCA
GCTGGGCTGGGGTTGGGGCTGCTGTGAGGAAAACCTGCCATTGTGGCCCTGGAGAGTCACCAGCAGCTCTTGGGAAGGACTTGCTGGGAG
GCTGAGAGAGGCTTTGGGCACAGCCTGCTGTCTTTTCCATTTCCTAAAGTTTACTTCATTGTCTTGAGGCTTCCAGGTTTTGTTTTTGTT
TTTGCCAAAGTAGAAAAGGCAGGTGGTGGGCGGCTGGCAGGGAGTGCGGGTCCCCGCCCCTCTTCAGTCCTGCCCTCCCCTCCTCAGTCC
TGCCCACCCCGTGCAGCCCATGCTGAGGCTGCAGTGGTGTCGTGGGTGTTACGTGCAGGAACGTGGAGACCCTGACGTGGGCTCACTGCG
TTTGGTTTTCTTTTCAGAACTTGGGAGCCCCCAGGGAGGGGCTAGTGTTGGTAGGTCCTAGACGTGGTTCCCTCCAGCCTCCCCAAAATC
AACCCTGGTGTTGAGAGAACGTCCTTCTGTCCATCGTGGGTAACAGCCTTGGGGAGGGTGCAGAGCTCTGCAGAGCCATGGGCCAGGTGG
GGCTGCCTCAGTCCTGTCCCCTTGGGCACTGAGGAGAGGGGCCCATTCACCTTTCTCCTAGAATGCTGTTGTAAATAAACAAATGGATCC

>In-frame_ENST00000367054_ENST00000397901_TCGA-VS-A953-01A_SOD2_chr6_160113693_-_CHMP1A_chr16_89713739_length(amino acids)=238AA_start in transcript=61_stop in transcript=777
MLSRAVCGTSRQLAPVLGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVTEEKYQEALAKGDQEYGPGDQSPGQG
PEHHGPAEGLLSDGQVRAAGAEPGRPYIGDGGLHELGHHPDHAAGAGGQPHHADRRGEWPGGAGPAQPAARGRLCRGRELCAQPGGPAVT

--------------------------------------------------------------
>In-frame_ENST00000367054_ENST00000535997_TCGA-VS-A953-01A_SOD2_chr6_160113693_-_CHMP1A_chr16_89713739_length(transcript)=2229nt_BP=287nt
GTGGCTTCGGCAGCGGCTTCAGCAGATCGGCGGCATCAGCGGTAGCACCAGCACTAGCAGCATGTTGAGCCGGGCAGTGTGCGGCACCAG
CAGGCAGCTGGCTCCGGTTTTGGGGTATCTGGGCTCCAGGCAGAAGCACAGCCTCCCCGACCTGCCCTACGACTACGGCGCCCTGGAACC
TCACATCAACGCGCAGATCATGCAGCTGCACCACAGCAAGCACCACGCGGCCTACGTGAACAACCTGAACGTCACCGAGGAGAAGTACCA
GGAGGCGTTGGCCAAGGGTGACCAAGAATATGGCCCAGGTGACCAAAGCCCTGGACAAGGCCCTGAGCACCATGGACCTGCAGAAGGTCT
CCTCAGTGATGGACAGGTTCGAGCAGCAGGTGCAGAACCTGGACGTCCATACATCGGTGATGGAGGACTCCATGAGCTCGGCCACCACCC
TGACCACGCCGCAGGAGCAGGTGGACAGCCTCATCATGCAGATCGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAGCTCAGCCAGCTGC
CCGAGGGCGCCTCTGCCGTGGGCGAGAGCTCTGTGCGCAGCCAGGAGGACCAGCTGTCACGGAGGTTGGCCGCCTTGAGGAACTAGCCGT
GCCCCGCCGGTGTGCACCGCCTCTGCCCCGTGATGTGCTGGAAGGCTCCTGTCCTCTCCCCACCGCGTCTTGCCTTTGTGCTGACCCCGC
GGGGCTGCGGCCGGCAGCCACTCTGCGTCTCTCACCTGCCAGGCCTGCGTGGCCTTAGGGTTGTTCCTGTTCTTTTAGGTTGGGCGGTGG
GTCTGTGTCCTGGTGTTGAGTTTCTGCAAATTTCTGGGGGTGATTTCTGTGACTCTGGGCCCACAGCGGGGAGGCCAAGAGGGGCCCTGT
GGACTTTCACCCAGCACTGTGGGGGCCTTCAGACTCTGGGGCAGCAGACATGCTGCTTCCCATCAGCCAGAGGGGGTCAGGGCTGCCCTG
TTGCCAAACAACTCCCTGAGGCCTCTCCGCACCACCTCAGCGGGCAGGAGGTCCCACCATGTGGACAGACATAGCCCAAGGAGGCACCAC
AGGTCTATGTGTGCTGGGGGATGTCAGGTGCCACCCAACGCTGTCCTGGTGGTATTTACAATGACATCCTCCTCCTCCATCACTCCAGGG
GTGGTGTCTCGGCCGCCCCTACCAGCTGGCTGAGCCCCCTGGCCTCCTGCGCTCCCTCACTTCCCTCAGTTCCCAAAGCTGCCCAGTCCA
TGGGGACAGAACCGTCACTCAGATCCACATTCAAGTGTGCCCACCCTGCAGTCTTCATCCTCACTCAGCTGCTGCCTCTGGAGGTGCCTT
TGGCCACATGTGCTGTGCTGTTTGTCTCCTCGACAGGGAGCCTGTCCACCAGCAGGCTGCGGTCCCAGCGGGTGCGTCTGCAGCTCCTCC
CCTTGGGCAGCCTGGTTCTCCCGGAGGACCTTTCCTTGGGGCCCTGCTTCATGACGATGCTGCCTGTGTCACCCTCTACCATCTGTAAAC
AACTGGGTGCCTTCCCCGACCACACCCCAATGCCTTCCCAGCTTGGAAGCCAAGGCAGCTGATGAAGGGAGCTCAGGAGAGCCGTCTTCA
GCTGGGCTGGGGTTGGGGCTGCTGTGAGGAAAACCTGCCATTGTGGCCCTGGAGAGTCACCAGCAGCTCTTGGGAAGGACTTGCTGGGAG
GCTGAGAGAGGCTTTGGGCACAGCCTGCTGTCTTTTCCATTTCCTAAAGTTTACTTCATTGTCTTGAGGCTTCCAGGTTTTGTTTTTGTT
TTTGCCAAAGTAGAAAAGGCAGGTGGTGGGCGGCTGGCAGGGAGTGCGGGTCCCCGCCCCTCTTCAGTCCTGCCCTCCCCTCCTCAGTCC
TGCCCACCCCGTGCAGCCCATGCTGAGGCTGCAGTGGTGTCGTGGGTGTTACGTGCAGGAACGTGGAGACCCTGACGTGGGCTCACTGCG
TTTGGTTTTCTTTTCAGAACTTGGGAGCCCCCAGGGAGGGGCTAGTGTTGGTAGGTCCTAGACGTGGTTCCCTCCAGCCTCCCCAAAATC
AACCCTGGTGTTGAGAGAACGTCCTTCTGTCCATCGTGGGTAACAGCCTTGGGGAGGGTGCAGAGCTCTGCAGAGCCATGGGCCAGGTGG

>In-frame_ENST00000367054_ENST00000535997_TCGA-VS-A953-01A_SOD2_chr6_160113693_-_CHMP1A_chr16_89713739_length(amino acids)=238AA_start in transcript=61_stop in transcript=777
MLSRAVCGTSRQLAPVLGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVTEEKYQEALAKGDQEYGPGDQSPGQG
PEHHGPAEGLLSDGQVRAAGAEPGRPYIGDGGLHELGHHPDHAAGAGGQPHHADRRGEWPGGAGPAQPAARGRLCRGRELCAQPGGPAVT

--------------------------------------------------------------
>In-frame_ENST00000367054_ENST00000550102_TCGA-VS-A953-01A_SOD2_chr6_160113693_-_CHMP1A_chr16_89713739_length(transcript)=803nt_BP=287nt
GTGGCTTCGGCAGCGGCTTCAGCAGATCGGCGGCATCAGCGGTAGCACCAGCACTAGCAGCATGTTGAGCCGGGCAGTGTGCGGCACCAG
CAGGCAGCTGGCTCCGGTTTTGGGGTATCTGGGCTCCAGGCAGAAGCACAGCCTCCCCGACCTGCCCTACGACTACGGCGCCCTGGAACC
TCACATCAACGCGCAGATCATGCAGCTGCACCACAGCAAGCACCACGCGGCCTACGTGAACAACCTGAACGTCACCGAGGAGAAGTACCA
GGAGGCGTTGGCCAAGGGTGACCAAGAATATGGCCCAGGTGACCAAAGCCCTGGACAAGGCCCTGAGCACCATGGACCTGCAGAAGGTCT
CCTCAGTGATGGACAGGTTCGAGCAGCAGGTGCAGAACCTGGACGTCCATACATCGGTGATGGAGGACTCCATGAGCTCGGCCACCACCC
TGACCACGCCGCAGGAGCAGGTGGACAGCCTCATCATGCAGATCGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAGCTCAGCCAGCTGC
CCGAGGGCGCCTCTGCCGTGGGCGAGAGCTCTGTGCGCAGCCAGGAGGACCAGCTGTCACGGAGGTTGGCCGCCTTGAGGAACTAGCCGT
GCCCCGCCGGTGTGCACCGCCTCTGCCCCGTGATGTGCTGGAAGGCTCCTGTCCTCTCCCCACCGCGTCTTGCCTTTGTGCTGACCCCGC

>In-frame_ENST00000367054_ENST00000550102_TCGA-VS-A953-01A_SOD2_chr6_160113693_-_CHMP1A_chr16_89713739_length(amino acids)=238AA_start in transcript=61_stop in transcript=777
MLSRAVCGTSRQLAPVLGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVTEEKYQEALAKGDQEYGPGDQSPGQG
PEHHGPAEGLLSDGQVRAAGAEPGRPYIGDGGLHELGHHPDHAAGAGGQPHHADRRGEWPGGAGPAQPAARGRLCRGRELCAQPGGPAVT

--------------------------------------------------------------
>In-frame_ENST00000444946_ENST00000253475_TCGA-VS-A953-01A_SOD2_chr6_160113693_-_CHMP1A_chr16_89713739_length(transcript)=2267nt_BP=300nt
ACTCGTGGCTGTGGTGGCTTCGGCAGCGGCTTCAGCAGATCGGCGGCATCAGCGGTAGCACCAGCACTAGCAGCATGTTGAGCCGGGCAG
TGTGCGGCACCAGCAGGCAGCTGGCTCCGGTTTTGGGGTATCTGGGCTCCAGGCAGAAGCACAGCCTCCCCGACCTGCCCTACGACTACG
GCGCCCTGGAACCTCACATCAACGCGCAGATCATGCAGCTGCACCACAGCAAGCACCACGCGGCCTACGTGAACAACCTGAACGTCACCG
AGGAGAAGTACCAGGAGGCGTTGGCCAAGGGTGACCAAGAATATGGCCCAGGTGACCAAAGCCCTGGACAAGGCCCTGAGCACCATGGAC
CTGCAGAAGGTCTCCTCAGTGATGGACAGGTTCGAGCAGCAGGTGCAGAACCTGGACGTCCATACATCGGTGATGGAGGACTCCATGAGC
TCGGCCACCACCCTGACCACGCCGCAGGAGCAGGTGGACAGCCTCATCATGCAGATCGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAG
CTCAGCCAGCTGCCCGAGGGCGCCTCTGCCGTGGGCGAGAGCTCTGTGCGCAGCCAGGAGGACCAGCTGTCACGGAGGTTGGCCGCCTTG
AGGAACTAGCCGTGCCCCGCCGGTGTGCACCGCCTCTGCCCCGTGATGTGCTGGAAGGCTCCTGTCCTCTCCCCACCGCGTCTTGCCTTT
GTGCTGACCCCGCGGGGCTGCGGCCGGCAGCCACTCTGCGTCTCTCACCTGCCAGGCCTGCGTGGCCTTAGGGTTGTTCCTGTTCTTTTA
GGTTGGGCGGTGGGTCTGTGTCCTGGTGTTGAGTTTCTGCAAATTTCTGGGGGTGATTTCTGTGACTCTGGGCCCACAGCGGGGAGGCCA
AGAGGGGCCCTGTGGACTTTCACCCAGCACTGTGGGGGCCTTCAGACTCTGGGGCAGCAGACATGCTGCTTCCCATCAGCCAGAGGGGGT
CAGGGCTGCCCTGTTGCCAAACAACTCCCTGAGGCCTCTCCGCACCACCTCAGCGGGCAGGAGGTCCCACCATGTGGACAGACATAGCCC
AAGGAGGCACCACAGGTCTATGTGTGCTGGGGGATGTCAGGTGCCACCCAACGCTGTCCTGGTGGTATTTACAATGACATCCTCCTCCTC
CATCACTCCAGGGGTGGTGTCTCGGCCGCCCCTACCAGCTGGCTGAGCCCCCTGGCCTCCTGCGCTCCCTCACTTCCCTCAGTTCCCAAA
GCTGCCCAGTCCATGGGGACAGAACCGTCACTCAGATCCACATTCAAGTGTGCCCACCCTGCAGTCTTCATCCTCACTCAGCTGCTGCCT
CTGGAGGTGCCTTTGGCCACATGTGCTGTGCTGTTTGTCTCCTCGACAGGGAGCCTGTCCACCAGCAGGCTGCGGTCCCAGCGGGTGCGT
CTGCAGCTCCTCCCCTTGGGCAGCCTGGTTCTCCCGGAGGACCTTTCCTTGGGGCCCTGCTTCATGACGATGCTGCCTGTGTCACCCTCT
ACCATCTGTAAACAACTGGGTGCCTTCCCCGACCACACCCCAATGCCTTCCCAGCTTGGAAGCCAAGGCAGCTGATGAAGGGAGCTCAGG
AGAGCCGTCTTCAGCTGGGCTGGGGTTGGGGCTGCTGTGAGGAAAACCTGCCATTGTGGCCCTGGAGAGTCACCAGCAGCTCTTGGGAAG
GACTTGCTGGGAGGCTGAGAGAGGCTTTGGGCACAGCCTGCTGTCTTTTCCATTTCCTAAAGTTTACTTCATTGTCTTGAGGCTTCCAGG
TTTTGTTTTTGTTTTTGCCAAAGTAGAAAAGGCAGGTGGTGGGCGGCTGGCAGGGAGTGCGGGTCCCCGCCCCTCTTCAGTCCTGCCCTC
CCCTCCTCAGTCCTGCCCACCCCGTGCAGCCCATGCTGAGGCTGCAGTGGTGTCGTGGGTGTTACGTGCAGGAACGTGGAGACCCTGACG
TGGGCTCACTGCGTTTGGTTTTCTTTTCAGAACTTGGGAGCCCCCAGGGAGGGGCTAGTGTTGGTAGGTCCTAGACGTGGTTCCCTCCAG
CCTCCCCAAAATCAACCCTGGTGTTGAGAGAACGTCCTTCTGTCCATCGTGGGTAACAGCCTTGGGGAGGGTGCAGAGCTCTGCAGAGCC
ATGGGCCAGGTGGGGCTGCCTCAGTCCTGTCCCCTTGGGCACTGAGGAGAGGGGCCCATTCACCTTTCTCCTAGAATGCTGTTGTAAATA

>In-frame_ENST00000444946_ENST00000253475_TCGA-VS-A953-01A_SOD2_chr6_160113693_-_CHMP1A_chr16_89713739_length(amino acids)=260AA_start in transcript=8_stop in transcript=790
MWWLRQRLQQIGGISGSTSTSSMLSRAVCGTSRQLAPVLGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVTEEK
YQEALAKGDQEYGPGDQSPGQGPEHHGPAEGLLSDGQVRAAGAEPGRPYIGDGGLHELGHHPDHAAGAGGQPHHADRRGEWPGGAGPAQP

--------------------------------------------------------------
>In-frame_ENST00000337404_ENST00000253475_TCGA-VS-A953-01A_SOD2_chr6_160113693_-_CHMP1A_chr16_89713739_length(transcript)=2304nt_BP=337nt
GCGCTTTCTTAAGGCCCGCGGGCGGCGCAGGAGCGGCACTCGTGGCTGTGGTGGCTTCGGCAGCGGCTTCAGCAGATCGGCGGCATCAGC
GGTAGCACCAGCACTAGCAGCATGTTGAGCCGGGCAGTGTGCGGCACCAGCAGGCAGCTGGCTCCGGTTTTGGGGTATCTGGGCTCCAGG
CAGAAGCACAGCCTCCCCGACCTGCCCTACGACTACGGCGCCCTGGAACCTCACATCAACGCGCAGATCATGCAGCTGCACCACAGCAAG
CACCACGCGGCCTACGTGAACAACCTGAACGTCACCGAGGAGAAGTACCAGGAGGCGTTGGCCAAGGGTGACCAAGAATATGGCCCAGGT
GACCAAAGCCCTGGACAAGGCCCTGAGCACCATGGACCTGCAGAAGGTCTCCTCAGTGATGGACAGGTTCGAGCAGCAGGTGCAGAACCT
GGACGTCCATACATCGGTGATGGAGGACTCCATGAGCTCGGCCACCACCCTGACCACGCCGCAGGAGCAGGTGGACAGCCTCATCATGCA
GATCGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAGCTCAGCCAGCTGCCCGAGGGCGCCTCTGCCGTGGGCGAGAGCTCTGTGCGCAG
CCAGGAGGACCAGCTGTCACGGAGGTTGGCCGCCTTGAGGAACTAGCCGTGCCCCGCCGGTGTGCACCGCCTCTGCCCCGTGATGTGCTG
GAAGGCTCCTGTCCTCTCCCCACCGCGTCTTGCCTTTGTGCTGACCCCGCGGGGCTGCGGCCGGCAGCCACTCTGCGTCTCTCACCTGCC
AGGCCTGCGTGGCCTTAGGGTTGTTCCTGTTCTTTTAGGTTGGGCGGTGGGTCTGTGTCCTGGTGTTGAGTTTCTGCAAATTTCTGGGGG
TGATTTCTGTGACTCTGGGCCCACAGCGGGGAGGCCAAGAGGGGCCCTGTGGACTTTCACCCAGCACTGTGGGGGCCTTCAGACTCTGGG
GCAGCAGACATGCTGCTTCCCATCAGCCAGAGGGGGTCAGGGCTGCCCTGTTGCCAAACAACTCCCTGAGGCCTCTCCGCACCACCTCAG
CGGGCAGGAGGTCCCACCATGTGGACAGACATAGCCCAAGGAGGCACCACAGGTCTATGTGTGCTGGGGGATGTCAGGTGCCACCCAACG
CTGTCCTGGTGGTATTTACAATGACATCCTCCTCCTCCATCACTCCAGGGGTGGTGTCTCGGCCGCCCCTACCAGCTGGCTGAGCCCCCT
GGCCTCCTGCGCTCCCTCACTTCCCTCAGTTCCCAAAGCTGCCCAGTCCATGGGGACAGAACCGTCACTCAGATCCACATTCAAGTGTGC
CCACCCTGCAGTCTTCATCCTCACTCAGCTGCTGCCTCTGGAGGTGCCTTTGGCCACATGTGCTGTGCTGTTTGTCTCCTCGACAGGGAG
CCTGTCCACCAGCAGGCTGCGGTCCCAGCGGGTGCGTCTGCAGCTCCTCCCCTTGGGCAGCCTGGTTCTCCCGGAGGACCTTTCCTTGGG
GCCCTGCTTCATGACGATGCTGCCTGTGTCACCCTCTACCATCTGTAAACAACTGGGTGCCTTCCCCGACCACACCCCAATGCCTTCCCA
GCTTGGAAGCCAAGGCAGCTGATGAAGGGAGCTCAGGAGAGCCGTCTTCAGCTGGGCTGGGGTTGGGGCTGCTGTGAGGAAAACCTGCCA
TTGTGGCCCTGGAGAGTCACCAGCAGCTCTTGGGAAGGACTTGCTGGGAGGCTGAGAGAGGCTTTGGGCACAGCCTGCTGTCTTTTCCAT
TTCCTAAAGTTTACTTCATTGTCTTGAGGCTTCCAGGTTTTGTTTTTGTTTTTGCCAAAGTAGAAAAGGCAGGTGGTGGGCGGCTGGCAG
GGAGTGCGGGTCCCCGCCCCTCTTCAGTCCTGCCCTCCCCTCCTCAGTCCTGCCCACCCCGTGCAGCCCATGCTGAGGCTGCAGTGGTGT
CGTGGGTGTTACGTGCAGGAACGTGGAGACCCTGACGTGGGCTCACTGCGTTTGGTTTTCTTTTCAGAACTTGGGAGCCCCCAGGGAGGG
GCTAGTGTTGGTAGGTCCTAGACGTGGTTCCCTCCAGCCTCCCCAAAATCAACCCTGGTGTTGAGAGAACGTCCTTCTGTCCATCGTGGG
TAACAGCCTTGGGGAGGGTGCAGAGCTCTGCAGAGCCATGGGCCAGGTGGGGCTGCCTCAGTCCTGTCCCCTTGGGCACTGAGGAGAGGG

>In-frame_ENST00000337404_ENST00000253475_TCGA-VS-A953-01A_SOD2_chr6_160113693_-_CHMP1A_chr16_89713739_length(amino acids)=260AA_start in transcript=45_stop in transcript=827
MWWLRQRLQQIGGISGSTSTSSMLSRAVCGTSRQLAPVLGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVTEEK
YQEALAKGDQEYGPGDQSPGQGPEHHGPAEGLLSDGQVRAAGAEPGRPYIGDGGLHELGHHPDHAAGAGGQPHHADRRGEWPGGAGPAQP

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SOD2-CHMP1A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SOD2-CHMP1A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SOD2-CHMP1A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneSOD2C0033578Prostatic Neoplasms8CTD_human
HgeneSOD2C0376358Malignant neoplasm of prostate8CTD_human
HgeneSOD2C0235874Disease Exacerbation7CTD_human
HgeneSOD2C0006826Malignant Neoplasms6CTD_human
HgeneSOD2C0027626Neoplasm Invasiveness6CTD_human
HgeneSOD2C0027651Neoplasms6CTD_human
HgeneSOD2C0035126Reperfusion Injury6CTD_human
HgeneSOD2C0086692Benign Neoplasm6CTD_human
HgeneSOD2C0007621Neoplastic Cell Transformation5CTD_human
HgeneSOD2C0018801Heart failure5CTD_human
HgeneSOD2C0018802Congestive heart failure5CTD_human
HgeneSOD2C0023212Left-Sided Heart Failure5CTD_human
HgeneSOD2C0235527Heart Failure, Right-Sided5CTD_human
HgeneSOD2C1959583Myocardial Failure5CTD_human
HgeneSOD2C1961112Heart Decompensation5CTD_human
HgeneSOD2C0006142Malignant neoplasm of breast4CTD_human
HgeneSOD2C0007114Malignant neoplasm of skin4CTD_human
HgeneSOD2C0024623Malignant neoplasm of stomach4CTD_human
HgeneSOD2C0025500Mesothelioma4CTD_human
HgeneSOD2C0027627Neoplasm Metastasis4CTD_human
HgeneSOD2C0036341Schizophrenia4PSYGENET
HgeneSOD2C0037286Skin Neoplasms4CTD_human
HgeneSOD2C0038356Stomach Neoplasms4CTD_human
HgeneSOD2C0678222Breast Carcinoma4CTD_human
HgeneSOD2C1257931Mammary Neoplasms, Human4CTD_human
HgeneSOD2C1458155Mammary Neoplasms4CTD_human
HgeneSOD2C1708349Hereditary Diffuse Gastric Cancer4CTD_human
HgeneSOD2C2239176Liver carcinoma4CTD_human
HgeneSOD2C4704874Mammary Carcinoma, Human4CTD_human
HgeneSOD2C0003873Rheumatoid Arthritis3CTD_human
HgeneSOD2C0007786Brain Ischemia3CTD_human
HgeneSOD2C0020538Hypertensive disease3CTD_human
HgeneSOD2C0024232Lymphatic Metastasis3CTD_human
HgeneSOD2C0028754Obesity3CTD_human
HgeneSOD2C0029408Degenerative polyarthritis3CTD_human
HgeneSOD2C0030567Parkinson Disease3CTD_human
HgeneSOD2C0086743Osteoarthrosis Deformans3CTD_human
HgeneSOD2C0270715Degenerative Diseases, Central Nervous System3CTD_human
HgeneSOD2C0524851Neurodegenerative Disorders3CTD_human
HgeneSOD2C0751733Degenerative Diseases, Spinal Cord3CTD_human
HgeneSOD2C0917798Cerebral Ischemia3CTD_human
HgeneSOD2C0002152Alloxan Diabetes2CTD_human
HgeneSOD2C0002896Sideroblastic anemia2CTD_human
HgeneSOD2C0003129Anoxemia2CTD_human
HgeneSOD2C0003130Anoxia2CTD_human
HgeneSOD2C0004153Atherosclerosis2CTD_human
HgeneSOD2C0005586Bipolar Disorder2PSYGENET
HgeneSOD2C0005684Malignant neoplasm of urinary bladder2CTD_human
HgeneSOD2C0005695Bladder Neoplasm2CTD_human
HgeneSOD2C0007097Carcinoma2CTD_human
HgeneSOD2C0007131Non-Small Cell Lung Carcinoma2CTD_human
HgeneSOD2C0007137Squamous cell carcinoma2CTD_human
HgeneSOD2C0007193Cardiomyopathy, Dilated2CTD_human
HgeneSOD2C0009402Colorectal Carcinoma2CTD_human
HgeneSOD2C0009404Colorectal Neoplasms2CTD_human
HgeneSOD2C0011853Diabetes Mellitus, Experimental2CTD_human
HgeneSOD2C0014859Esophageal Neoplasms2CTD_human
HgeneSOD2C0022116Ischemia2CTD_human
HgeneSOD2C0022658Kidney Diseases2CTD_human
HgeneSOD2C0026640Mouth Neoplasms2CTD_human
HgeneSOD2C0027540Necrosis2CTD_human
HgeneSOD2C0032927Precancerous Conditions2CTD_human
HgeneSOD2C0034535Radiation Syndrome2CTD_human
HgeneSOD2C0038433Streptozotocin Diabetes2CTD_human
HgeneSOD2C0042164Uveitis2CTD_human
HgeneSOD2C0085207Gestational Diabetes2CTD_human
HgeneSOD2C0153381Malignant neoplasm of mouth2CTD_human
HgeneSOD2C0162674Chronic progressive external ophthalmoplegia2CTD_human
HgeneSOD2C0205696Anaplastic carcinoma2CTD_human
HgeneSOD2C0205697Carcinoma, Spindle-Cell2CTD_human
HgeneSOD2C0205698Undifferentiated carcinoma2CTD_human
HgeneSOD2C0205699Carcinomatosis2CTD_human
HgeneSOD2C0242184Hypoxia2CTD_human
HgeneSOD2C0279626Squamous cell carcinoma of esophagus2CTD_human
HgeneSOD2C0282313Condition, Preneoplastic2CTD_human
HgeneSOD2C0546837Malignant neoplasm of esophagus2CTD_human
HgeneSOD2C0700292Hypoxemia2CTD_human
HgeneSOD2C0919267ovarian neoplasm2CTD_human
HgeneSOD2C1140680Malignant neoplasm of ovary2CTD_human
HgeneSOD2C1449563Cardiomyopathy, Familial Idiopathic2CTD_human
HgeneSOD2C1510432Radiation Sickness2CTD_human
HgeneSOD2C1563937Atherogenesis2CTD_human
HgeneSOD2C0001418Adenocarcinoma1CTD_human
HgeneSOD2C0001787Osteoporosis, Age-Related1CTD_human
HgeneSOD2C0001925Albuminuria1CTD_human
HgeneSOD2C0001969Alcoholic Intoxication1PSYGENET
HgeneSOD2C0002390Extrinsic allergic alveolitis1CTD_human
HgeneSOD2C0002395Alzheimer's Disease1CTD_human
HgeneSOD2C0002736Amyotrophic Lateral Sclerosis1CTD_human
HgeneSOD2C0002871Anemia1CTD_human
HgeneSOD2C0003493Aortic Diseases1CTD_human
HgeneSOD2C0004045Asphyxia Neonatorum1CTD_human
HgeneSOD2C0004364Autoimmune Diseases1CTD_human
HgeneSOD2C0006118Brain Neoplasms1CTD_human
HgeneSOD2C0007102Malignant tumor of colon1CTD_human
HgeneSOD2C0007134Renal Cell Carcinoma1CTD_human
HgeneSOD2C0007682CNS disorder1CTD_human
HgeneSOD2C0007787Transient Ischemic Attack1CTD_human
HgeneSOD2C0009375Colonic Neoplasms1CTD_human
HgeneSOD2C0011265Presenile dementia1CTD_human
HgeneSOD2C0011570Mental Depression1PSYGENET
HgeneSOD2C0011574Involutional Depression1CTD_human
HgeneSOD2C0011581Depressive disorder1PSYGENET
HgeneSOD2C0011860Diabetes Mellitus, Non-Insulin-Dependent1CTD_human
HgeneSOD2C0011881Diabetic Nephropathy1CTD_human
HgeneSOD2C0014866Esophageal Stenosis1CTD_human
HgeneSOD2C0014868Esophagitis1CTD_human
HgeneSOD2C0015695Fatty Liver1CTD_human
HgeneSOD2C0015967Fever1CTD_human
HgeneSOD2C0016059Fibrosis1CTD_human
HgeneSOD2C0017667Nodular glomerulosclerosis1CTD_human
HgeneSOD2C0018200Granuloma, Respiratory Tract1CTD_human
HgeneSOD2C0018800Cardiomegaly1CTD_human
HgeneSOD2C0019193Hepatitis, Toxic1CTD_human
HgeneSOD2C0020542Pulmonary Hypertension1CTD_human
HgeneSOD2C0020550Hyperthyroidism1CTD_human
HgeneSOD2C0020615Hypoglycemia1CTD_human
HgeneSOD2C0021364Male infertility1CTD_human
HgeneSOD2C0021367Mammary Ductal Carcinoma1CTD_human
HgeneSOD2C0021655Insulin Resistance1CTD_human
HgeneSOD2C0022333Jacksonian Seizure1CTD_human
HgeneSOD2C0022665Kidney Neoplasm1CTD_human
HgeneSOD2C0022672Acute Kidney Tubular Necrosis1CTD_human
HgeneSOD2C0023891Liver Cirrhosis, Alcoholic1CTD_human
HgeneSOD2C0024115Lung diseases1CTD_human
HgeneSOD2C0024668Mammary Neoplasms, Experimental1CTD_human
HgeneSOD2C0024796Marfan Syndrome1CTD_human
HgeneSOD2C0025312Meningomyelocele1CTD_human
HgeneSOD2C0026764Multiple Myeloma1CTD_human
HgeneSOD2C0027051Myocardial Infarction1CTD_human
HgeneSOD2C0027726Nephrotic Syndrome1CTD_human
HgeneSOD2C0027746Nerve Degeneration1CTD_human
HgeneSOD2C0029456Osteoporosis1CTD_human
HgeneSOD2C0029459Osteoporosis, Senile1CTD_human
HgeneSOD2C0030246Pustulosis of Palms and Soles1CTD_human
HgeneSOD2C0030297Pancreatic Neoplasm1CTD_human
HgeneSOD2C0030354Papilloma1CTD_human
HgeneSOD2C0032580Adenomatous Polyposis Coli1CTD_human
HgeneSOD2C0033141Cardiomyopathies, Primary1CTD_human
HgeneSOD2C0033860Psoriasis1CTD_human
HgeneSOD2C0033937Psychoses, Drug1CTD_human
HgeneSOD2C0033941Psychoses, Substance-Induced1CTD_human
HgeneSOD2C0035222Respiratory Distress Syndrome, Adult1CTD_human
HgeneSOD2C0036202Sarcoidosis1CTD_human
HgeneSOD2C0036529Myocardial Diseases, Secondary1CTD_human
HgeneSOD2C0036572Seizures1CTD_human
HgeneSOD2C0036980Shock, Cardiogenic1CTD_human
HgeneSOD2C0037268Skin Abnormalities1CTD_human
HgeneSOD2C0037274Dermatologic disorders1CTD_human
HgeneSOD2C0040411Tongue Neoplasms1CTD_human
HgeneSOD2C0041408Turner Syndrome1CTD_human
HgeneSOD2C0042373Vascular Diseases1CTD_human
HgeneSOD2C0079744Diffuse Large B-Cell Lymphoma1CTD_human
HgeneSOD2C0086664Myelocele1CTD_human
HgeneSOD2C0149958Complex partial seizures1CTD_human
HgeneSOD2C0151526Premature Birth1CTD_human
HgeneSOD2C0151744Myocardial Ischemia1CTD_human
HgeneSOD2C0152013Adenocarcinoma of lung (disorder)1CTD_human
HgeneSOD2C0153349Malignant neoplasm of tongue1CTD_human
HgeneSOD2C0153633Malignant neoplasm of brain1CTD_human
HgeneSOD2C0162309Adrenoleukodystrophy1CTD_human
HgeneSOD2C0162671MELAS Syndrome1CTD_human
HgeneSOD2C0162871Aortic Aneurysm, Abdominal1CTD_human
HgeneSOD2C0205641Adenocarcinoma, Basal Cell1CTD_human
HgeneSOD2C0205642Adenocarcinoma, Oxyphilic1CTD_human
HgeneSOD2C0205643Carcinoma, Cribriform1CTD_human
HgeneSOD2C0205644Carcinoma, Granular Cell1CTD_human
HgeneSOD2C0205645Adenocarcinoma, Tubular1CTD_human
HgeneSOD2C0205874Papilloma, Squamous Cell1CTD_human
HgeneSOD2C0205875Papillomatosis1CTD_human
HgeneSOD2C0206061Pneumonia, Interstitial1CTD_human
HgeneSOD2C0206062Lung Diseases, Interstitial1CTD_human
HgeneSOD2C0206160Reticulocytosis1CTD_human
HgeneSOD2C0234533Generalized seizures1CTD_human
HgeneSOD2C0234535Clonic Seizures1CTD_human
HgeneSOD2C0235974Pancreatic carcinoma1CTD_human
HgeneSOD2C0238281Middle Cerebral Artery Syndrome1CTD_human
HgeneSOD2C0238461Anaplastic thyroid carcinoma1CTD_human
HgeneSOD2C0242526Gonadal Dysgenesis, 45,X1CTD_human
HgeneSOD2C0242698Ventricular Dysfunction, Left1CTD_human
HgeneSOD2C0242992Multiple Chemical Sensitivity1CTD_human
HgeneSOD2C0268255Farber Lipogranulomatosis1CTD_human
HgeneSOD2C0268583Methylmalonic acidemia1CTD_human
HgeneSOD2C0270824Visual seizure1CTD_human
HgeneSOD2C0270844Tonic Seizures1CTD_human
HgeneSOD2C0270846Epileptic drop attack1CTD_human
HgeneSOD2C0271708Fasting Hypoglycemia1CTD_human
HgeneSOD2C0271710Reactive hypoglycemia1CTD_human
HgeneSOD2C0274861Arsenic Poisoning, Inorganic1CTD_human
HgeneSOD2C0274862Nervous System, Organic Arsenic Poisoning1CTD_human
HgeneSOD2C0276496Familial Alzheimer Disease (FAD)1CTD_human
HgeneSOD2C0279702Conventional (Clear Cell) Renal Cell Carcinoma1CTD_human
HgeneSOD2C0311375Arsenic Poisoning1CTD_human
HgeneSOD2C0345967Malignant mesothelioma1CTD_human
HgeneSOD2C0346647Malignant neoplasm of pancreas1CTD_human
HgeneSOD2C0376618Endotoxemia1CTD_human
HgeneSOD2C0393554Amyotrophic Lateral Sclerosis With Dementia1CTD_human
HgeneSOD2C0422850Seizures, Somatosensory1CTD_human
HgeneSOD2C0422852Seizures, Auditory1CTD_human
HgeneSOD2C0422853Olfactory seizure1CTD_human
HgeneSOD2C0422854Gustatory seizure1CTD_human
HgeneSOD2C0422855Vertiginous seizure1CTD_human
HgeneSOD2C0472381Posterior Circulation Transient Ischemic Attack1CTD_human
HgeneSOD2C0494463Alzheimer Disease, Late Onset1CTD_human
HgeneSOD2C0494475Tonic - clonic seizures1CTD_human
HgeneSOD2C0496899Benign neoplasm of brain, unspecified1CTD_human
HgeneSOD2C0520459Necrotizing Enterocolitis1CTD_human
HgeneSOD2C0543859Amyotrophic Lateral Sclerosis, Guam Form1CTD_human
HgeneSOD2C0546126Acute Confusional Senile Dementia1CTD_human
HgeneSOD2C0740376Middle Cerebral Artery Thrombosis1CTD_human
HgeneSOD2C0740391Middle Cerebral Artery Occlusion1CTD_human
HgeneSOD2C0740392Infarction, Middle Cerebral Artery1CTD_human
HgeneSOD2C0740457Malignant neoplasm of kidney1CTD_human
HgeneSOD2C0750900Alzheimer's Disease, Focal Onset1CTD_human
HgeneSOD2C0750901Alzheimer Disease, Early Onset1CTD_human
HgeneSOD2C0750974Brain Tumor, Primary1CTD_human
HgeneSOD2C0750977Recurrent Brain Neoplasm1CTD_human
HgeneSOD2C0750979Primary malignant neoplasm of brain1CTD_human
HgeneSOD2C0751019Carotid Circulation Transient Ischemic Attack1CTD_human
HgeneSOD2C0751020Transient Ischemic Attack, Vertebrobasilar Circulation1CTD_human
HgeneSOD2C0751021Crescendo Transient Ischemic Attacks1CTD_human
HgeneSOD2C0751022Brain Stem Ischemia, Transient1CTD_human
HgeneSOD2C0751056Non-epileptic convulsion1CTD_human
HgeneSOD2C0751110Single Seizure1CTD_human
HgeneSOD2C0751123Atonic Absence Seizures1CTD_human
HgeneSOD2C0751316Acquired Meningomyelocele1CTD_human
HgeneSOD2C0751406Post-Traumatic Osteoporosis1CTD_human
HgeneSOD2C0751494Convulsive Seizures1CTD_human
HgeneSOD2C0751495Seizures, Focal1CTD_human
HgeneSOD2C0751496Seizures, Sensory1CTD_human
HgeneSOD2C0751651Mitochondrial Diseases1CTD_human
HgeneSOD2C0751845Middle Cerebral Artery Embolus1CTD_human
HgeneSOD2C0751846Left Middle Cerebral Artery Infarction1CTD_human
HgeneSOD2C0751847Embolic Infarction, Middle Cerebral Artery1CTD_human
HgeneSOD2C0751848Thrombotic Infarction, Middle Cerebral Artery1CTD_human
HgeneSOD2C0751849Right Middle Cerebral Artery Infarction1CTD_human
HgeneSOD2C0751851Arsenic Encephalopathy1CTD_human
HgeneSOD2C0751852Arsenic Induced Polyneuropathy1CTD_human
HgeneSOD2C0752347Lewy Body Disease1CTD_human
HgeneSOD2C0848676Subfertility, Male1CTD_human
HgeneSOD2C0860207Drug-Induced Liver Disease1CTD_human
HgeneSOD2C0878544Cardiomyopathies1CTD_human
HgeneSOD2C0917731Male sterility1CTD_human
HgeneSOD2C0917805Transient Cerebral Ischemia1CTD_human
HgeneSOD2C0920563Insulin Sensitivity1CTD_human
HgeneSOD2C0948089Acute Coronary Syndrome1CTD_human
HgeneSOD2C0949855Electron Transport Chain Deficiencies, Mitochondrial1CTD_human
HgeneSOD2C0949856Oxidative Phosphorylation Deficiencies1CTD_human
HgeneSOD2C0949857Mitochondrial Respiratory Chain Deficiencies1CTD_human
HgeneSOD2C1134719Invasive Ductal Breast Carcinoma1CTD_human
HgeneSOD2C1168401Squamous cell carcinoma of the head and neck1CTD_human
HgeneSOD2C1262760Hepatitis, Drug-Induced1CTD_human
HgeneSOD2C1266042Chromophobe Renal Cell Carcinoma1CTD_human
HgeneSOD2C1266043Sarcomatoid Renal Cell Carcinoma1CTD_human
HgeneSOD2C1266044Collecting Duct Carcinoma of the Kidney1CTD_human
HgeneSOD2C1269683Major Depressive Disorder1CTD_human
HgeneSOD2C1306837Papillary Renal Cell Carcinoma1CTD_human
HgeneSOD2C1383860Cardiac Hypertrophy1CTD_human
HgeneSOD2C1527168Bonnevie-Ullrich Syndrome1CTD_human
HgeneSOD2C1527231Adrenomyeloneuropathy1CTD_human
HgeneSOD2C1527335Transient Ischemic Attack, Anterior Circulation1CTD_human
HgeneSOD2C1527390Neoplasms, Intracranial1CTD_human
HgeneSOD2C1571983Involutional paraphrenia1CTD_human
HgeneSOD2C1571984Psychosis, Involutional1CTD_human
HgeneSOD2C1623038Cirrhosis1CTD_human
HgeneSOD2C1855119Methylmalonic aciduria1CTD_human
HgeneSOD2C1859317Cataract and cardiomyopathy1CTD_human
HgeneSOD2C2711227Steatohepatitis1CTD_human
HgeneSOD2C2713442Polyposis, Adenomatous Intestinal1CTD_human
HgeneSOD2C2713443Familial Intestinal Polyposis1CTD_human
HgeneSOD2C2931822Nasopharyngeal carcinoma1CTD_human
HgeneSOD2C3495874Nonepileptic Seizures1CTD_human
HgeneSOD2C3658290Drug-Induced Acute Liver Injury1CTD_human
HgeneSOD2C3714618Primary Hyperthyroidism1CTD_human
HgeneSOD2C4048158Convulsions1CTD_human
HgeneSOD2C4277682Chemical and Drug Induced Liver Injury1CTD_human
HgeneSOD2C4279912Chemically-Induced Liver Toxicity1CTD_human
HgeneSOD2C4316903Absence Seizures1CTD_human
HgeneSOD2C4317109Epileptic Seizures1CTD_human
HgeneSOD2C4317123Myoclonic Seizures1CTD_human
HgeneSOD2C4505436Generalized Absence Seizures1CTD_human
HgeneSOD2C4551650Esophageal Stricture1CTD_human
HgeneSOD2C4721453Peripheral Nervous System Diseases1CTD_human
HgeneSOD2C4721845Marfan Syndrome, Type I1CTD_human
TgeneCHMP1AC0266468Congenital pontocerebellar hypoplasia1GENOMICS_ENGLAND
TgeneCHMP1AC3554209Congenital pontocerebellar hypoplasia type 81CTD_human;GENOMICS_ENGLAND;ORPHANET