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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:SPAG7-DNAH17 (FusionGDB2 ID:84860) |
Fusion Gene Summary for SPAG7-DNAH17 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SPAG7-DNAH17 | Fusion gene ID: 84860 | Hgene | Tgene | Gene symbol | SPAG7 | DNAH17 | Gene ID | 9552 | 8632 |
| Gene name | sperm associated antigen 7 | dynein axonemal heavy chain 17 | |
| Synonyms | ACRP|FSA-1 | DNAHL1|DNEL2|SPGF39 | |
| Cytomap | 17p13.2 | 17q25.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | sperm-associated antigen 7 | dynein heavy chain 17, axonemalaxonemal beta dynein heavy chain 17axonemal dynein heavy chain-like protein 1ciliary dynein heavy chain 17ciliary dynein heavy chain-like protein 1dynein light chain 2, axonemaldynein, axonemal, heavy polypeptide 17 | |
| Modification date | 20200313 | 20200320 | |
| UniProtAcc | . | Q9UFH2 | |
| Ensembl transtripts involved in fusion gene | ENST00000575142, ENST00000206020, ENST00000573366, ENST00000571023, | ENST00000389840, ENST00000585328, ENST00000586052, | |
| Fusion gene scores | * DoF score | 6 X 4 X 6=144 | 15 X 16 X 11=2640 |
| # samples | 6 | 19 | |
| ** MAII score | log2(6/144*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(19/2640*10)=-3.79646660591487 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SPAG7 [Title/Abstract] AND DNAH17 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | SPAG7(4871015)-DNAH17(76471915), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across SPAG7 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene breakpoints across DNAH17 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | HNSC | TCGA-P3-A5QE-01A | SPAG7 | chr17 | 4871015 | - | DNAH17 | chr17 | 76471915 | - |
| ChimerDB4 | HNSC | TCGA-P3-A5QE-01A | SPAG7 | chr17 | 4871015 | - | DNAH17 | chr17 | 76471915 | - |
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Fusion Gene ORF analysis for SPAG7-DNAH17 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000575142 | ENST00000389840 | SPAG7 | chr17 | 4871015 | - | DNAH17 | chr17 | 76471915 | - |
| In-frame | ENST00000575142 | ENST00000585328 | SPAG7 | chr17 | 4871015 | - | DNAH17 | chr17 | 76471915 | - |
| 5CDS-5UTR | ENST00000575142 | ENST00000586052 | SPAG7 | chr17 | 4871015 | - | DNAH17 | chr17 | 76471915 | - |
| In-frame | ENST00000206020 | ENST00000389840 | SPAG7 | chr17 | 4871015 | - | DNAH17 | chr17 | 76471915 | - |
| In-frame | ENST00000206020 | ENST00000585328 | SPAG7 | chr17 | 4871015 | - | DNAH17 | chr17 | 76471915 | - |
| 5CDS-5UTR | ENST00000206020 | ENST00000586052 | SPAG7 | chr17 | 4871015 | - | DNAH17 | chr17 | 76471915 | - |
| intron-3CDS | ENST00000573366 | ENST00000389840 | SPAG7 | chr17 | 4871015 | - | DNAH17 | chr17 | 76471915 | - |
| intron-3CDS | ENST00000573366 | ENST00000585328 | SPAG7 | chr17 | 4871015 | - | DNAH17 | chr17 | 76471915 | - |
| intron-5UTR | ENST00000573366 | ENST00000586052 | SPAG7 | chr17 | 4871015 | - | DNAH17 | chr17 | 76471915 | - |
| 5UTR-3CDS | ENST00000571023 | ENST00000389840 | SPAG7 | chr17 | 4871015 | - | DNAH17 | chr17 | 76471915 | - |
| 5UTR-3CDS | ENST00000571023 | ENST00000585328 | SPAG7 | chr17 | 4871015 | - | DNAH17 | chr17 | 76471915 | - |
| 5UTR-5UTR | ENST00000571023 | ENST00000586052 | SPAG7 | chr17 | 4871015 | - | DNAH17 | chr17 | 76471915 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000575142 | SPAG7 | chr17 | 4871015 | - | ENST00000389840 | DNAH17 | chr17 | 76471915 | - | 5626 | 71 | 164 | 5416 | 1750 |
| ENST00000575142 | SPAG7 | chr17 | 4871015 | - | ENST00000585328 | DNAH17 | chr17 | 76471915 | - | 5515 | 71 | 164 | 5305 | 1713 |
| ENST00000206020 | SPAG7 | chr17 | 4871015 | - | ENST00000389840 | DNAH17 | chr17 | 76471915 | - | 5708 | 153 | 246 | 5498 | 1750 |
| ENST00000206020 | SPAG7 | chr17 | 4871015 | - | ENST00000585328 | DNAH17 | chr17 | 76471915 | - | 5597 | 153 | 246 | 5387 | 1713 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000575142 | ENST00000389840 | SPAG7 | chr17 | 4871015 | - | DNAH17 | chr17 | 76471915 | - | 0.002553187 | 0.9974468 |
| ENST00000575142 | ENST00000585328 | SPAG7 | chr17 | 4871015 | - | DNAH17 | chr17 | 76471915 | - | 0.002834141 | 0.99716586 |
| ENST00000206020 | ENST00000389840 | SPAG7 | chr17 | 4871015 | - | DNAH17 | chr17 | 76471915 | - | 0.0026573 | 0.99734277 |
| ENST00000206020 | ENST00000585328 | SPAG7 | chr17 | 4871015 | - | DNAH17 | chr17 | 76471915 | - | 0.002963275 | 0.9970367 |
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Fusion Genomic Features for SPAG7-DNAH17 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for SPAG7-DNAH17 |
| Go to FGviewer for the breakpoints of chr17:4871015-chr17:76471915 - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | DNAH17 |
| FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes. | FUNCTION: Force generating protein component of the outer dynein arms (ODAs) in the sperm flagellum. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (Probable). Plays a major role in sperm motility, implicated in sperm flagellar assembly and beating (PubMed:31178125). {ECO:0000269|PubMed:31178125, ECO:0000305|PubMed:31178125}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | DNAH17 | chr17:4871015 | chr17:76471915 | ENST00000389840 | 51 | 81 | 3027_3086 | 2704.0 | 4486.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | DNAH17 | chr17:4871015 | chr17:76471915 | ENST00000389840 | 51 | 81 | 3257_3309 | 2704.0 | 4486.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | DNAH17 | chr17:4871015 | chr17:76471915 | ENST00000389840 | 51 | 81 | 2801_2808 | 2704.0 | 4486.0 | Nucleotide binding | ATP | |
| Tgene | DNAH17 | chr17:4871015 | chr17:76471915 | ENST00000389840 | 51 | 81 | 2763_3012 | 2704.0 | 4486.0 | Region | AAA 4 | |
| Tgene | DNAH17 | chr17:4871015 | chr17:76471915 | ENST00000389840 | 51 | 81 | 3027_3313 | 2704.0 | 4486.0 | Region | Stalk | |
| Tgene | DNAH17 | chr17:4871015 | chr17:76471915 | ENST00000389840 | 51 | 81 | 3405_3632 | 2704.0 | 4486.0 | Region | AAA 5 | |
| Tgene | DNAH17 | chr17:4871015 | chr17:76471915 | ENST00000389840 | 51 | 81 | 3842_4068 | 2704.0 | 4486.0 | Region | AAA 6 | |
| Tgene | DNAH17 | chr17:4871015 | chr17:76471915 | ENST00000389840 | 51 | 81 | 4147_4182 | 2704.0 | 4486.0 | Repeat | Note=TPR 3 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SPAG7 | chr17:4871015 | chr17:76471915 | ENST00000206020 | - | 1 | 7 | 46_109 | 28.333333333333332 | 228.0 | Domain | R3H |
| Hgene | SPAG7 | chr17:4871015 | chr17:76471915 | ENST00000206020 | - | 1 | 7 | 122_139 | 28.333333333333332 | 228.0 | Motif | Nuclear localization signal |
| Hgene | SPAG7 | chr17:4871015 | chr17:76471915 | ENST00000206020 | - | 1 | 7 | 35_51 | 28.333333333333332 | 228.0 | Motif | Nuclear localization signal |
| Tgene | DNAH17 | chr17:4871015 | chr17:76471915 | ENST00000389840 | 51 | 81 | 1847_1854 | 2704.0 | 4486.0 | Nucleotide binding | ATP | |
| Tgene | DNAH17 | chr17:4871015 | chr17:76471915 | ENST00000389840 | 51 | 81 | 2128_2135 | 2704.0 | 4486.0 | Nucleotide binding | ATP | |
| Tgene | DNAH17 | chr17:4871015 | chr17:76471915 | ENST00000389840 | 51 | 81 | 2455_2462 | 2704.0 | 4486.0 | Nucleotide binding | ATP | |
| Tgene | DNAH17 | chr17:4871015 | chr17:76471915 | ENST00000389840 | 51 | 81 | 1809_2030 | 2704.0 | 4486.0 | Region | AAA 1 | |
| Tgene | DNAH17 | chr17:4871015 | chr17:76471915 | ENST00000389840 | 51 | 81 | 1_1808 | 2704.0 | 4486.0 | Region | Stem | |
| Tgene | DNAH17 | chr17:4871015 | chr17:76471915 | ENST00000389840 | 51 | 81 | 2090_2311 | 2704.0 | 4486.0 | Region | AAA 2 | |
| Tgene | DNAH17 | chr17:4871015 | chr17:76471915 | ENST00000389840 | 51 | 81 | 2417_2665 | 2704.0 | 4486.0 | Region | AAA 3 | |
| Tgene | DNAH17 | chr17:4871015 | chr17:76471915 | ENST00000389840 | 51 | 81 | 1019_1052 | 2704.0 | 4486.0 | Repeat | Note=TPR 1 | |
| Tgene | DNAH17 | chr17:4871015 | chr17:76471915 | ENST00000389840 | 51 | 81 | 1702_1736 | 2704.0 | 4486.0 | Repeat | Note=TPR 2 |
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Fusion Gene Sequence for SPAG7-DNAH17 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >In-frame_ENST00000575142_ENST00000389840_TCGA-P3-A5QE-01A_SPAG7_chr17_4871015_-_DNAH17_chr17_76471915_length(transcript)=5626nt_BP=71nt GGGCTCCATCCTGAGCTCCATGGAGAAGCCACCCAGCCTCGGTGACCAGGAGACTCGGCGCAAGGCCCGAGGATCTTGGTGATGAACTCT TATTTGCCAAGCCAAATATCTTCTGCCACTTTGCTCAAGGGATTGGCGATCCCAAATATGTTCCTGTAACCGACATGGCTCCTCTGAACA AGCTCCTCGTGGACGTCCTGGACAGCTACAATGAAGTTAATGCAGTCATGAATTTGGTGCTGTTTGAGGACGCCGTGGCTCACATCTGCA GGATTAATCGCATCCTGGAGTCTCCCCGGGGGAATGCCCTGCTGGTGGGGGTGGGCGGCAGTGGCAAACAGAGCCTCTCCCGCCTGGCAG CGTACATCAGCGGGCTTGACGTGTTTCAGATCACCCTCAAGAAGGGCTACGGGATCCCCGACCTCAAGATTGACCTCGCTGCTCAGTACA TAAAGGCTGCCGTGAAGAACGTTCCCTCGGTGTTCCTGATGACAGACTCCCAGGTGGCCGAGGAGCAGTTTCTGGTGCTGATCAATGACC TGCTGGCCTCAGGAGAGATCCCTGGGCTGTTTATGGAGGACGAGGTGGAGAACATCATCTCCTCCATGCGACCCCAAGTCAAGTCCCTTG GCATGAATGACACTCGGGAAACATGTTGGAAGTTCTTCATCGAAAAAGTGCGCAGACAGCTCAAGGTGATCCTGTGTTTCTCCCCTGTGG GCTCCGTGCTGCGGGTACGAGCCAGAAAGTTCCCAGCTGTGGTCAACTGCACGGCCATCGACTGGTTCCACGAGTGGCCGGAAGATGCGC TGGTGTCCGTCAGCGCCCGCTTCCTGGAGGAGACTGAGGGGATTCCGTGGGAAGTCAAGGCCTCCATCAGCTTCTTCATGTCCTACGTGC ACACCACCGTCAACGAGATGTCCAGGGTATACCTGGCTACTGAGAGGCGCTACAACTACACCACACCCAAAACCTTTCTGGAGCAGATCA AACTGTACCAGAACCTGCTGGCCAAGAAGAGAACGGAACTTGTTGCCAAAATCGAGAGGCTGGAGAACGGCCTGATGAAGCTGCAGAGCA CGGCTTCCCAGGTGGATGATTTGAAAGCCAAGTTGGCGATTCAGGAGGCTGAGCTCAAGCAGAAGAATGAGAGCGCAGACCAACTGATCC AGGTGGTCGGCATCGAGGCCGAGAAGGTCAGCAAAGAGAAGGCCATTGCTGACCAGGAAGAAGTCAAGGTCGAGGTCATCAATAAGAACG TCACTGAGAAGCAAAAGGCCTGTGAAACAGACCTGGCCAAAGCAGAACCGGCCCTGCTGGCAGCCCAGGAGGCTCTGGACACTCTGAATA AGAACAACCTGACAGAGCTGAAGTCCTTTGGGTCCCCGCCGGATGCTGTGGTCAACGTCACCGCCGCCGTCATGATTCTGACCGCACCTG GGGGCAAGATCCCCAAGGACAAGAGCTGGAAGGCGGCCAAGATCATGATGGGCAAGGTGGACACCTTCCTAGACTCCCTGAAGAAGTTCG ACAAGGAGCACATCCCTGAGGCCTGCCTGAAGGCCTTCAAGCCCTACCAAGGCAACCCGACGTTCGACCCCGAGTTCATCCGCTCCAAGT CCACGGCCGCCGCCGGCCTGTGCTCCTGGTGCATCAACATCGTCCGCTTCTACGAGGTCTACTGCGACGTGGCGCCCAAGAGGCAGGCAC TGGAGGAGGCTAATGCAGAGCTGGCAGAGGCACAAGAGAAGCTGTCCCGGATCAAAAACAAGATTGCCGAACTTAACGCCAACCTGAGCA ACCTAACCTCAGCGTTTGAAAAAGCAACAGCTGAGAAAATCAAGTGTCAGCAAGAGGCCGATGCCACGAACAGGGTGATCTTACTGGCGA ACAGGCTGGTCGGGGGATTAGCATCGGAAAACATCCGCTGGGCTGAGTCTGTGGAGAACTTCAGGAGCCAGGGGGTCACGCTGTGTGGGG ACGTCCTGCTCATCTCTGCCTTCGTGTCCTACGTGGGCTACTTCACCAAGAAATACCGGAATGAGCTGATGGAGAAATTCTGGATCCCTT ACATACATAACTTAAAGGTCCCCATCCCGATCACGAATGGCCTGGATCCCTTGAGCCTGCTGACAGATGACGCGGACGTGGCCACCTGGA ACAACCAGGGCCTCCCCAGCGACCGCATGTCCACCGAGAATGCCACCATCCTGGGCAACACCGAGCGGTGGCCGCTGATCGTGGACGCCC AGCTCCAAGGAATCAAGTGGATCAAAAACAAATACAGGAGTGAACTGAAAGCCATCCGCCTGGGACAGAAGAGCTACCTGGATGTCATCG AGCAGGCCATCTCGGAAGGGGACACCTTGCTCATTGAGAACATCGGCGAAACCGTGGACCCCGTGCTGGACCCTCTACTGGGCAGGAACA CGATTAAAAAGGGAAAGTACATTAAGATCGGTGACAAGGAGGTGGAGTACCACCCCAAGTTCCGCCTGATCCTACACACCAAGTACTTCA ACCCACACTACAAGCCAGAGATGCAGGCTCAGTGCACCCTCATCAACTTCCTGGTCACCAGGGATGGACTCGAGGACCAACTCTTGGCCG CTGTGGTGGCCAAAGAGCGCCCAGATCTGGAACAGCTGAAGGCAAACCTCACCAAGTCTCAAAACGAATTTAAGATTGTTCTGAAAGAGC TGGAAGATTCGCTCCTGGCCCGTCTGTCGGCTGCGTCGGGGAACTTTCTGGGAGACACGGCCTTGGTGGAGAATCTGGAGACCACCAAGC ACACAGCCAGCGAGATCGAGGAGAAGGTGGTGGAGGCAAAAATCACAGAAGTTAAAATCAACGAAGCGAGAGAGAACTACCGCCCGGCTG CGGAGAGGGCATCTCTGCTCTACTTCATACTGAACGATCTCAACAAAATCAACCCCGTCTACCAGTTCTCCCTCAAGGCCTTCAACGTGG TGTTTGAGAAAGCCATCCAGAGGACCACCCCTGCCAACGAGGTGAAGCAGCGGGTGATCAACCTGACGGACGAGATCACCTACTCCGTCT ACATGTACACGGCCCGGGGACTCTTCGAGAGGGACAAACTCATTTTCCTGGCACAAGTTACGTTTCAGGTCCTGTCCATGAAGAAGGAGC TGAACCCAGTGGAGCTGGATTTCCTCCTGCGGTTCCCTTTTAAGGCCGGAGTGGTCTCACCAGTGGACTTCCTCCAGCATCAAGGCTGGG GCGGGATCAAGGCCCTCTCGGAGATGGATGAGTTCAAAAATCTGGACAGTGACATCGAAGGATCTGCCAAGCGCTGGAAAAAGCTGGTGG AGTCGGAAGCCCCCGAGAAGGAGATCTTCCCCAAGGAGTGGAAGAACAAGACGGCCCTGCAGAAGCTGTGCATGGTGCGCTGCCTGCGGC CAGATCGCATGACCTACGCTATCAAGAACTTCGTGGAGGAAAAGATGGGCAGCAAGTTCGTGGAAGGCCGGAGTGTTGAGTTTTCTAAGT CCTACGAGGAGAGCAGCCCCTCCACGTCAATCTTCTTCATCCTCTCCCCGGGGGTTGACCCCTTGAAAGACGTGGAAGCCCTGGGAAAAA AACTAGGGTTTACCATAGACAATGGAAAACTCCATAATGTGTCCCTGGGGCAGGGACAAGAGGTGGTGGCTGAGAACGCCCTGGACGTGG CTGCAGAGAAAGGACACTGGGTCATTCTGCAGGTACGAGGGGGCCAGCACTGCAGGAATATCCACCTGGTGGCCCGGTGGCTGGGAACAC TGGACAAGAAGCTGGAGCACTACAGCACGGGCAGCCATGAGGACTACCGGGTGTTCATCAGCGCGGAGCCTGCCCCCAGCCCCGAGACCC ACATCATCCCCCAGGGCATTCTGGAGAACGCCATCAAGATCACCAACGAGCCCCCCACGGGCATGCACGCCAACTTGCACAAGGCCCTGG ACCTGTTCACCCAGGACACCCTGGAGATGTGCACCAAGGAGATGGAGTTCAAGTGCATGCTCTTCGCCCTGTGCTACTTCCACGCTGTGG TGGCAGAGAGGCGCAAGTTCGGCGCCCAGGGCTGGAACCGGTCGTACCCCTTCAACAACGGGGACCTCACCATCTCCATCAACGTGCTCT ACAACTACCTGGAGGCCAACCCCAAGGTGCCCTGGGACGATCTCCGCTACCTTTTTGGTGAAATCATGTATGGCGGCCACATCACAGATG ACTGGGACCGTCGGCTGTGCAGGACCTACCTGGCTGAATACATCCGGACGGAGATGCTGGAGGGAGACGTCCTGCTGGCCCCCGGCTTTC AGATCCCCCCCAACCTGGACTACAAGGGTTACCACGAATACATCGATGAGAACCTGCCCCCTGAGAGTCCCTATCTGTATGGCCTGCACC CCAACGCAGAGATTGGCTTTCTGACGGTCACCTCAGAGAAGCTGTTCCGCACTGTCCTGGAAATGCAGCCAAAAGAGACGGACTCGGGGG CAGGCACGGGAGTGTCCCGCGAGGAGAAGGCAGGATCTTTGAAACTGCTCCCAAGCGAGAGGAAGGGGGAGGATCTAGAACTGAGGAGGG GGGGCTGTCCGGGGACTGGCTTCCAGGTGAAGGCCGTGCTGGACGACATCCTGGAGAAGATTCCGGAGACTTTCAACATGGCTGAGATCA TGGCAAAGGCAGCGGAAAAGACCCCCTACGTGGTAGTCGCCTTTCAAGAATGTGAAAGAATGAACATCCTGACCAACGAAATGCGCCGTT CGCTCAAGGAGCTGAACCTGGGGCTGAAGGGAGAACTGACCATCACGACCGACGTGGAAGATCTGTCCACGGCTCTCTTCTATGACACCG TGCCTGATACGTGGGTGGCCCGGGCCTACCCCTCCATGATGGGCCTGGCGGCCTGGTACGCAGACCTGCTGCTCCGCATCAGGGAACTCG AGGCCTGGACGACAGACTTTGCCCTGCCCACCACCGTGTGGCTGGCCGGCTTCTTCAACCCCCAGTCGTTCCTCACGGCCATCATGCAGT CCATGGCCAGGAAGAACGAGTGGCCCCTGGACAAGATGTGTCTGTCTGTCGAGGTGACCAAGAAAAACCGAGAGGACATGACCGCTCCTC CGCGAGAGGGCTCCTACGTGTACGGACTCTTCATGGAAGGGGCTCGCTGGGACACCCAGACTGGAGTCATCGCTGAAGCGCGGCTGAAAG AGCTGACCCCGGCCATGCCTGTCATCTTCATCAAGGCCATTCCTGTGGACCGCATGGAGACCAAGAACATCTATGAGTGTCCCGTGTACA AAACACGCATCCGCGGCCCCACCTATGTCTGGACCTTTAACTTGAAGACCAAAGAGAAGGCAGCGAAGTGGATCCTGGCAGCCGTGGCGC TGCTCCTACAGGTTTAGCTCGCTCCTGCCTCACAGCCCACACTCCCTGGGGCTGGACCACAACTCAGCCCTTCACCTGTGCACCTGTGAC TTATTCTTTACAGGAACTGGTGGTGGTTTTTCGTTCTCTTAAATAATCAGGTGCTTTGTAACCAAGCACATCGGAACCAGAGGGTGGAGG >In-frame_ENST00000575142_ENST00000389840_TCGA-P3-A5QE-01A_SPAG7_chr17_4871015_-_DNAH17_chr17_76471915_length(amino acids)=1750AA_start in transcript=164_stop in transcript=5416 MAPLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKID LAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVIL CFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPWEVKASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKT FLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVE VINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLD SLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAEL NANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELME KFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQKS YLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLE DQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARE NYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVL SMKKELNPVELDFLLRFPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCM VRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAE NALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKLEHYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHAN LHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYG GHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPK ETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECERMNILT NEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFL TAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIY -------------------------------------------------------------- >In-frame_ENST00000575142_ENST00000585328_TCGA-P3-A5QE-01A_SPAG7_chr17_4871015_-_DNAH17_chr17_76471915_length(transcript)=5515nt_BP=71nt GGGCTCCATCCTGAGCTCCATGGAGAAGCCACCCAGCCTCGGTGACCAGGAGACTCGGCGCAAGGCCCGAGGATCTTGGTGATGAACTCT TATTTGCCAAGCCAAATATCTTCTGCCACTTTGCTCAAGGGATTGGCGATCCCAAATATGTTCCTGTAACCGACATGGCTCCTCTGAACA AGCTCCTCGTGGACGTCCTGGACAGCTACAATGAAGTTAATGCAGTCATGAATTTGGTGCTGTTTGAGGACGCCGTGGCTCACATCTGCA GGATTAATCGCATCCTGGAGTCTCCCCGGGGGAATGCCCTGCTGGTGGGGGTGGGCGGCAGTGGCAAACAGAGCCTCTCCCGCCTGGCAG CGTACATCAGCGGGCTTGACGTGTTTCAGATCACCCTCAAGAAGGGCTACGGGATCCCCGACCTCAAGATTGACCTCGCTGCTCAGTACA TAAAGGCTGCCGTGAAGAACGTTCCCTCGGTGTTCCTGATGACAGACTCCCAGGTGGCCGAGGAGCAGTTTCTGGTGCTGATCAATGACC TGCTGGCCTCAGGAGAGATCCCTGGGCTGTTTATGGAGGACGAGGTGGAGAACATCATCTCCTCCATGCGACCCCAAGTCAAGTCCCTTG GCATGAATGACACTCGGGAAACATGTTGGAAGTTCTTCATCGAAAAAGTGCGCAGACAGCTCAAGGTGATCCTGTGTTTCTCCCCTGTGG GCTCCGTGCTGCGGGTACGAGCCAGAAAGTTCCCAGCTGTGGTCAACTGCACGGCCATCGACTGGTTCCACGAGTGGCCGGAAGATGCGC TGGTGTCCGTCAGCGCCCGCTTCCTGGAGGAGACTGAGGGGATTCCGTGGGAAGTCAAGGCCTCCATCAGCTTCTTCATGTCCTACGTGC ACACCACCGTCAACGAGATGTCCAGGGTATACCTGGCTACTGAGAGGCGCTACAACTACACCACACCCAAAACCTTTCTGGAGCAGATCA AACTGTACCAGAACCTGCTGGCCAAGAAGAGAACGGAACTTGTTGCCAAAATCGAGAGGCTGGAGAACGGCCTGATGAAGCTGCAGAGCA CGGCTTCCCAGGTGGATGATTTGAAAGCCAAGTTGGCGATTCAGGAGGCTGAGCTCAAGCAGAAGAATGAGAGCGCAGACCAACTGATCC AGGTGGTCGGCATCGAGGCCGAGAAGGTCAGCAAAGAGAAGGCCATTGCTGACCAGGAAGAAGTCAAGGTCGAGGTCATCAATAAGAACG TCACTGAGAAGCAAAAGGCCTGTGAAACAGACCTGGCCAAAGCAGAACCGGCCCTGCTGGCAGCCCAGGAGGCTCTGGACACTCTGAATA AGAACAACCTGACAGAGCTGAAGTCCTTTGGGTCCCCGCCGGATGCTGTGGTCAACGTCACCGCCGCCGTCATGATTCTGACCGCACCTG GGGGCAAGATCCCCAAGGACAAGAGCTGGAAGGCGGCCAAGATCATGATGGGCAAGGTGGACACCTTCCTAGACTCCCTGAAGAAGTTCG ACAAGGAGCACATCCCTGAGGCCTGCCTGAAGGCCTTCAAGCCCTACCAAGGCAACCCGACGTTCGACCCCGAGTTCATCCGCTCCAAGT CCACGGCCGCCGCCGGCCTGTGCTCCTGGTGCATCAACATCGTCCGCTTCTACGAGGTCTACTGCGACGTGGCGCCCAAGAGGCAGGCAC TGGAGGAGGCTAATGCAGAGCTGGCAGAGGCACAAGAGAAGCTGTCCCGGATCAAAAACAAGATTGCCGAACTTAACGCCAACCTGAGCA ACCTAACCTCAGCGTTTGAAAAAGCAACAGCTGAGAAAATCAAGTGTCAGCAAGAGGCCGATGCCACGAACAGGGTGATCTTACTGGCGA ACAGGCTGGTCGGGGGATTAGCATCGGAAAACATCCGCTGGGCTGAGTCTGTGGAGAACTTCAGGAGCCAGGGGGTCACGCTGTGTGGGG ACGTCCTGCTCATCTCTGCCTTCGTGTCCTACGTGGGCTACTTCACCAAGAAATACCGGAATGAGCTGATGGAGAAATTCTGGATCCCTT ACATACATAACTTAAAGGTCCCCATCCCGATCACGAATGGCCTGGATCCCTTGAGCCTGCTGACAGATGACGCGGACGTGGCCACCTGGA ACAACCAGGGCCTCCCCAGCGACCGCATGTCCACCGAGAATGCCACCATCCTGGGCAACACCGAGCGGTGGCCGCTGATCGTGGACGCCC AGCTCCAAGGAATCAAGTGGATCAAAAACAAATACAGGAGTGAACTGAAAGCCATCCGCCTGGGACAGAAGAGCTACCTGGATGTCATCG AGCAGGCCATCTCGGAAGGGGACACCTTGCTCATTGAGAACATCGGCGAAACCGTGGACCCCGTGCTGGACCCTCTACTGGGCAGGAACA CGATTAAAAAGGGAAAGTACATTAAGATCGGTGACAAGGAGGTGGAGTACCACCCCAAGTTCCGCCTGATCCTACACACCAAGTACTTCA ACCCACACTACAAGCCAGAGATGCAGGCTCAGTGCACCCTCATCAACTTCCTGGTCACCAGGGATGGACTCGAGGACCAACTCTTGGCCG CTGTGGTGGCCAAAGAGCGCCCAGATCTGGAACAGCTGAAGGCAAACCTCACCAAGTCTCAAAACGAATTTAAGATTGTTCTGAAAGAGC TGGAAGATTCGCTCCTGGCCCGTCTGTCGGCTGCGTCGGGGAACTTTCTGGGAGACACGGCCTTGGTGGAGAATCTGGAGACCACCAAGC ACACAGCCAGCGAGATCGAGGAGAAGGTGGTGGAGGCAAAAATCACAGAAGTTAAAATCAACGAAGCGAGAGAGAACTACCGCCCGGCTG CGGAGAGGGCATCTCTGCTCTACTTCATACTGAACGATCTCAACAAAATCAACCCCGTCTACCAGTTCTCCCTCAAGGCCTTCAACGTGG TGTTTGAGAAAGCCATCCAGAGGACCACCCCTGCCAACGAGGTGAAGCAGCGGGTGATCAACCTGACGGACGAGATCACCTACTCCGTCT ACATGTACACGGCCCGGGGACTCTTCGAGAGGGACAAACTCATTTTCCTGGCACAAGTTACGTTTCAGGTCCTGTCCATGAAGAAGGAGC TGAACCCAGTGGAGCTGGATTTCCTCCTGCGGTTCCCTTTTAAGGCCGGAGTGGTCTCACCAGTGGACTTCCTCCAGCATCAAGGCTGGG GCGGGATCAAGGCCCTCTCGGAGATGGATGAGTTCAAAAATCTGGACAGTGACATCGAAGGATCTGCCAAGCGCTGGAAAAAGCTGGTGG AGTCGGAAGCCCCCGAGAAGGAGATCTTCCCCAAGGAGTGGAAGAACAAGACGGCCCTGCAGAAGCTGTGCATGGTGCGCTGCCTGCGGC CAGATCGCATGACCTACGCTATCAAGAACTTCGTGGAGGAAAAGATGGGCAGCAAGTTCGTGGAAGGCCGGAGTGTTGAGTTTTCTAAGT CCTACGAGGAGAGCAGCCCCTCCACGTCAATCTTCTTCATCCTCTCCCCGGGGGTTGACCCCTTGAAAGACGTGGAAGCCCTGGGAAAAA AACTAGGGTTTACCATAGACAATGGAAAACTCCATAATGTGTCCCTGGGGCAGGGACAAGAGGTGGTGGCTGAGAACGCCCTGGACGTGG CTGCAGAGAAAGGACACTGGGTCATTCTGCAGAATATCCACCTGGTGGCCCGGTGGCTGGGAACACTGGACAAGAAGCTGGAGCACTACA GCACGGGCAGCCATGAGGACTACCGGGTGTTCATCAGCGCGGAGCCTGCCCCCAGCCCCGAGACCCACATCATCCCCCAGGGCATTCTGG AGAACGCCATCAAGATCACCAACGAGCCCCCCACGGGCATGCACGCCAACTTGCACAAGGCCCTGGACCTGTTCACCCAGGACACCCTGG AGATGTGCACCAAGGAGATGGAGTTCAAGTGCATGCTCTTCGCCCTGTGCTACTTCCACGCTGTGGTGGCAGAGAGGCGCAAGTTCGGCG CCCAGGGCTGGAACCGGTCGTACCCCTTCAACAACGGGGACCTCACCATCTCCATCAACGTGCTCTACAACTACCTGGAGGCCAACCCCA AGGTGCCCTGGGACGATCTCCGCTACCTTTTTGGTGAAATCATGTATGGCGGCCACATCACAGATGACTGGGACCGTCGGCTGTGCAGGA CCTACCTGGCTGAATACATCCGGACGGAGATGCTGGAGGGAGACGTCCTGCTGGCCCCCGGCTTTCAGATCCCCCCCAACCTGGACTACA AGGGTTACCACGAATACATCGATGAGAACCTGCCCCCTGAGAGTCCCTATCTGTATGGCCTGCACCCCAACGCAGAGATTGGCTTTCTGA CGGTCACCTCAGAGAAGCTGTTCCGCACTGTCCTGGAAATGCAGCCAAAAGAGACGGACTCGGGGGCAGGCACGGGAGTGTCCCGCGAGG AGAAGGTGAAGGCCGTGCTGGACGACATCCTGGAGAAGATTCCGGAGACTTTCAACATGGCTGAGATCATGGCAAAGGCAGCGGAAAAGA CCCCCTACGTGGTAGTCGCCTTTCAAGAATGTGAAAGAATGAACATCCTGACCAACGAAATGCGCCGTTCGCTCAAGGAGCTGAACCTGG GGCTGAAGGGAGAACTGACCATCACGACCGACGTGGAAGATCTGTCCACGGCTCTCTTCTATGACACCGTGCCTGATACGTGGGTGGCCC GGGCCTACCCCTCCATGATGGGCCTGGCGGCCTGGTACGCAGACCTGCTGCTCCGCATCAGGGAACTCGAGGCCTGGACGACAGACTTTG CCCTGCCCACCACCGTGTGGCTGGCCGGCTTCTTCAACCCCCAGTCGTTCCTCACGGCCATCATGCAGTCCATGGCCAGGAAGAACGAGT GGCCCCTGGACAAGATGTGTCTGTCTGTCGAGGTGACCAAGAAAAACCGAGAGGACATGACCGCTCCTCCGCGAGAGGGCTCCTACGTGT ACGGACTCTTCATGGAAGGGGCTCGCTGGGACACCCAGACTGGAGTCATCGCTGAAGCGCGGCTGAAAGAGCTGACCCCGGCCATGCCTG TCATCTTCATCAAGGCCATTCCTGTGGACCGCATGGAGACCAAGAACATCTATGAGTGTCCCGTGTACAAAACACGCATCCGCGGCCCCA CCTATGTCTGGACCTTTAACTTGAAGACCAAAGAGAAGGCAGCGAAGTGGATCCTGGCAGCCGTGGCGCTGCTCCTACAGGTTTAGCTCG CTCCTGCCTCACAGCCCACACTCCCTGGGGCTGGACCACAACTCAGCCCTTCACCTGTGCACCTGTGACTTATTCTTTACAGGAACTGGT GGTGGTTTTTCGTTCTCTTAAATAATCAGGTGCTTTGTAACCAAGCACATCGGAACCAGAGGGTGGAGGTTGGTGTGGAAGAGGTGGGGC >In-frame_ENST00000575142_ENST00000585328_TCGA-P3-A5QE-01A_SPAG7_chr17_4871015_-_DNAH17_chr17_76471915_length(amino acids)=1713AA_start in transcript=164_stop in transcript=5305 MAPLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKID LAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVIL CFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPWEVKASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKT FLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVE VINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLD SLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAEL NANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELME KFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQKS YLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLE DQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARE NYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVL SMKKELNPVELDFLLRFPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCM VRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAE NALDVAAEKGHWVILQNIHLVARWLGTLDKKLEHYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLF TQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWD RRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGT GVSREEKVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVP DTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPR EGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKWILAAVALL -------------------------------------------------------------- >In-frame_ENST00000206020_ENST00000389840_TCGA-P3-A5QE-01A_SPAG7_chr17_4871015_-_DNAH17_chr17_76471915_length(transcript)=5708nt_BP=153nt GTTTCCGGCCTTAAAGGCATTCCGCCCTTCCCTTTAAGACGCACCGCCCCCTCTCAGTCACTCCCAAGATGGCGGACCTACTGGGCTCCA TCCTGAGCTCCATGGAGAAGCCACCCAGCCTCGGTGACCAGGAGACTCGGCGCAAGGCCCGAGGATCTTGGTGATGAACTCTTATTTGCC AAGCCAAATATCTTCTGCCACTTTGCTCAAGGGATTGGCGATCCCAAATATGTTCCTGTAACCGACATGGCTCCTCTGAACAAGCTCCTC GTGGACGTCCTGGACAGCTACAATGAAGTTAATGCAGTCATGAATTTGGTGCTGTTTGAGGACGCCGTGGCTCACATCTGCAGGATTAAT CGCATCCTGGAGTCTCCCCGGGGGAATGCCCTGCTGGTGGGGGTGGGCGGCAGTGGCAAACAGAGCCTCTCCCGCCTGGCAGCGTACATC AGCGGGCTTGACGTGTTTCAGATCACCCTCAAGAAGGGCTACGGGATCCCCGACCTCAAGATTGACCTCGCTGCTCAGTACATAAAGGCT GCCGTGAAGAACGTTCCCTCGGTGTTCCTGATGACAGACTCCCAGGTGGCCGAGGAGCAGTTTCTGGTGCTGATCAATGACCTGCTGGCC TCAGGAGAGATCCCTGGGCTGTTTATGGAGGACGAGGTGGAGAACATCATCTCCTCCATGCGACCCCAAGTCAAGTCCCTTGGCATGAAT GACACTCGGGAAACATGTTGGAAGTTCTTCATCGAAAAAGTGCGCAGACAGCTCAAGGTGATCCTGTGTTTCTCCCCTGTGGGCTCCGTG CTGCGGGTACGAGCCAGAAAGTTCCCAGCTGTGGTCAACTGCACGGCCATCGACTGGTTCCACGAGTGGCCGGAAGATGCGCTGGTGTCC GTCAGCGCCCGCTTCCTGGAGGAGACTGAGGGGATTCCGTGGGAAGTCAAGGCCTCCATCAGCTTCTTCATGTCCTACGTGCACACCACC GTCAACGAGATGTCCAGGGTATACCTGGCTACTGAGAGGCGCTACAACTACACCACACCCAAAACCTTTCTGGAGCAGATCAAACTGTAC CAGAACCTGCTGGCCAAGAAGAGAACGGAACTTGTTGCCAAAATCGAGAGGCTGGAGAACGGCCTGATGAAGCTGCAGAGCACGGCTTCC CAGGTGGATGATTTGAAAGCCAAGTTGGCGATTCAGGAGGCTGAGCTCAAGCAGAAGAATGAGAGCGCAGACCAACTGATCCAGGTGGTC GGCATCGAGGCCGAGAAGGTCAGCAAAGAGAAGGCCATTGCTGACCAGGAAGAAGTCAAGGTCGAGGTCATCAATAAGAACGTCACTGAG AAGCAAAAGGCCTGTGAAACAGACCTGGCCAAAGCAGAACCGGCCCTGCTGGCAGCCCAGGAGGCTCTGGACACTCTGAATAAGAACAAC CTGACAGAGCTGAAGTCCTTTGGGTCCCCGCCGGATGCTGTGGTCAACGTCACCGCCGCCGTCATGATTCTGACCGCACCTGGGGGCAAG ATCCCCAAGGACAAGAGCTGGAAGGCGGCCAAGATCATGATGGGCAAGGTGGACACCTTCCTAGACTCCCTGAAGAAGTTCGACAAGGAG CACATCCCTGAGGCCTGCCTGAAGGCCTTCAAGCCCTACCAAGGCAACCCGACGTTCGACCCCGAGTTCATCCGCTCCAAGTCCACGGCC GCCGCCGGCCTGTGCTCCTGGTGCATCAACATCGTCCGCTTCTACGAGGTCTACTGCGACGTGGCGCCCAAGAGGCAGGCACTGGAGGAG GCTAATGCAGAGCTGGCAGAGGCACAAGAGAAGCTGTCCCGGATCAAAAACAAGATTGCCGAACTTAACGCCAACCTGAGCAACCTAACC TCAGCGTTTGAAAAAGCAACAGCTGAGAAAATCAAGTGTCAGCAAGAGGCCGATGCCACGAACAGGGTGATCTTACTGGCGAACAGGCTG GTCGGGGGATTAGCATCGGAAAACATCCGCTGGGCTGAGTCTGTGGAGAACTTCAGGAGCCAGGGGGTCACGCTGTGTGGGGACGTCCTG CTCATCTCTGCCTTCGTGTCCTACGTGGGCTACTTCACCAAGAAATACCGGAATGAGCTGATGGAGAAATTCTGGATCCCTTACATACAT AACTTAAAGGTCCCCATCCCGATCACGAATGGCCTGGATCCCTTGAGCCTGCTGACAGATGACGCGGACGTGGCCACCTGGAACAACCAG GGCCTCCCCAGCGACCGCATGTCCACCGAGAATGCCACCATCCTGGGCAACACCGAGCGGTGGCCGCTGATCGTGGACGCCCAGCTCCAA GGAATCAAGTGGATCAAAAACAAATACAGGAGTGAACTGAAAGCCATCCGCCTGGGACAGAAGAGCTACCTGGATGTCATCGAGCAGGCC ATCTCGGAAGGGGACACCTTGCTCATTGAGAACATCGGCGAAACCGTGGACCCCGTGCTGGACCCTCTACTGGGCAGGAACACGATTAAA AAGGGAAAGTACATTAAGATCGGTGACAAGGAGGTGGAGTACCACCCCAAGTTCCGCCTGATCCTACACACCAAGTACTTCAACCCACAC TACAAGCCAGAGATGCAGGCTCAGTGCACCCTCATCAACTTCCTGGTCACCAGGGATGGACTCGAGGACCAACTCTTGGCCGCTGTGGTG GCCAAAGAGCGCCCAGATCTGGAACAGCTGAAGGCAAACCTCACCAAGTCTCAAAACGAATTTAAGATTGTTCTGAAAGAGCTGGAAGAT TCGCTCCTGGCCCGTCTGTCGGCTGCGTCGGGGAACTTTCTGGGAGACACGGCCTTGGTGGAGAATCTGGAGACCACCAAGCACACAGCC AGCGAGATCGAGGAGAAGGTGGTGGAGGCAAAAATCACAGAAGTTAAAATCAACGAAGCGAGAGAGAACTACCGCCCGGCTGCGGAGAGG GCATCTCTGCTCTACTTCATACTGAACGATCTCAACAAAATCAACCCCGTCTACCAGTTCTCCCTCAAGGCCTTCAACGTGGTGTTTGAG AAAGCCATCCAGAGGACCACCCCTGCCAACGAGGTGAAGCAGCGGGTGATCAACCTGACGGACGAGATCACCTACTCCGTCTACATGTAC ACGGCCCGGGGACTCTTCGAGAGGGACAAACTCATTTTCCTGGCACAAGTTACGTTTCAGGTCCTGTCCATGAAGAAGGAGCTGAACCCA GTGGAGCTGGATTTCCTCCTGCGGTTCCCTTTTAAGGCCGGAGTGGTCTCACCAGTGGACTTCCTCCAGCATCAAGGCTGGGGCGGGATC AAGGCCCTCTCGGAGATGGATGAGTTCAAAAATCTGGACAGTGACATCGAAGGATCTGCCAAGCGCTGGAAAAAGCTGGTGGAGTCGGAA GCCCCCGAGAAGGAGATCTTCCCCAAGGAGTGGAAGAACAAGACGGCCCTGCAGAAGCTGTGCATGGTGCGCTGCCTGCGGCCAGATCGC ATGACCTACGCTATCAAGAACTTCGTGGAGGAAAAGATGGGCAGCAAGTTCGTGGAAGGCCGGAGTGTTGAGTTTTCTAAGTCCTACGAG GAGAGCAGCCCCTCCACGTCAATCTTCTTCATCCTCTCCCCGGGGGTTGACCCCTTGAAAGACGTGGAAGCCCTGGGAAAAAAACTAGGG TTTACCATAGACAATGGAAAACTCCATAATGTGTCCCTGGGGCAGGGACAAGAGGTGGTGGCTGAGAACGCCCTGGACGTGGCTGCAGAG AAAGGACACTGGGTCATTCTGCAGGTACGAGGGGGCCAGCACTGCAGGAATATCCACCTGGTGGCCCGGTGGCTGGGAACACTGGACAAG AAGCTGGAGCACTACAGCACGGGCAGCCATGAGGACTACCGGGTGTTCATCAGCGCGGAGCCTGCCCCCAGCCCCGAGACCCACATCATC CCCCAGGGCATTCTGGAGAACGCCATCAAGATCACCAACGAGCCCCCCACGGGCATGCACGCCAACTTGCACAAGGCCCTGGACCTGTTC ACCCAGGACACCCTGGAGATGTGCACCAAGGAGATGGAGTTCAAGTGCATGCTCTTCGCCCTGTGCTACTTCCACGCTGTGGTGGCAGAG AGGCGCAAGTTCGGCGCCCAGGGCTGGAACCGGTCGTACCCCTTCAACAACGGGGACCTCACCATCTCCATCAACGTGCTCTACAACTAC CTGGAGGCCAACCCCAAGGTGCCCTGGGACGATCTCCGCTACCTTTTTGGTGAAATCATGTATGGCGGCCACATCACAGATGACTGGGAC CGTCGGCTGTGCAGGACCTACCTGGCTGAATACATCCGGACGGAGATGCTGGAGGGAGACGTCCTGCTGGCCCCCGGCTTTCAGATCCCC CCCAACCTGGACTACAAGGGTTACCACGAATACATCGATGAGAACCTGCCCCCTGAGAGTCCCTATCTGTATGGCCTGCACCCCAACGCA GAGATTGGCTTTCTGACGGTCACCTCAGAGAAGCTGTTCCGCACTGTCCTGGAAATGCAGCCAAAAGAGACGGACTCGGGGGCAGGCACG GGAGTGTCCCGCGAGGAGAAGGCAGGATCTTTGAAACTGCTCCCAAGCGAGAGGAAGGGGGAGGATCTAGAACTGAGGAGGGGGGGCTGT CCGGGGACTGGCTTCCAGGTGAAGGCCGTGCTGGACGACATCCTGGAGAAGATTCCGGAGACTTTCAACATGGCTGAGATCATGGCAAAG GCAGCGGAAAAGACCCCCTACGTGGTAGTCGCCTTTCAAGAATGTGAAAGAATGAACATCCTGACCAACGAAATGCGCCGTTCGCTCAAG GAGCTGAACCTGGGGCTGAAGGGAGAACTGACCATCACGACCGACGTGGAAGATCTGTCCACGGCTCTCTTCTATGACACCGTGCCTGAT ACGTGGGTGGCCCGGGCCTACCCCTCCATGATGGGCCTGGCGGCCTGGTACGCAGACCTGCTGCTCCGCATCAGGGAACTCGAGGCCTGG ACGACAGACTTTGCCCTGCCCACCACCGTGTGGCTGGCCGGCTTCTTCAACCCCCAGTCGTTCCTCACGGCCATCATGCAGTCCATGGCC AGGAAGAACGAGTGGCCCCTGGACAAGATGTGTCTGTCTGTCGAGGTGACCAAGAAAAACCGAGAGGACATGACCGCTCCTCCGCGAGAG GGCTCCTACGTGTACGGACTCTTCATGGAAGGGGCTCGCTGGGACACCCAGACTGGAGTCATCGCTGAAGCGCGGCTGAAAGAGCTGACC CCGGCCATGCCTGTCATCTTCATCAAGGCCATTCCTGTGGACCGCATGGAGACCAAGAACATCTATGAGTGTCCCGTGTACAAAACACGC ATCCGCGGCCCCACCTATGTCTGGACCTTTAACTTGAAGACCAAAGAGAAGGCAGCGAAGTGGATCCTGGCAGCCGTGGCGCTGCTCCTA CAGGTTTAGCTCGCTCCTGCCTCACAGCCCACACTCCCTGGGGCTGGACCACAACTCAGCCCTTCACCTGTGCACCTGTGACTTATTCTT TACAGGAACTGGTGGTGGTTTTTCGTTCTCTTAAATAATCAGGTGCTTTGTAACCAAGCACATCGGAACCAGAGGGTGGAGGTTGGTGTG >In-frame_ENST00000206020_ENST00000389840_TCGA-P3-A5QE-01A_SPAG7_chr17_4871015_-_DNAH17_chr17_76471915_length(amino acids)=1750AA_start in transcript=246_stop in transcript=5498 MAPLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKID LAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVIL CFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPWEVKASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKT FLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVE VINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLD SLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAEL NANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELME KFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQKS YLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLE DQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARE NYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVL SMKKELNPVELDFLLRFPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCM VRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAE NALDVAAEKGHWVILQVRGGQHCRNIHLVARWLGTLDKKLEHYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHAN LHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYG GHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPK ETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECERMNILT NEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFL TAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIY -------------------------------------------------------------- >In-frame_ENST00000206020_ENST00000585328_TCGA-P3-A5QE-01A_SPAG7_chr17_4871015_-_DNAH17_chr17_76471915_length(transcript)=5597nt_BP=153nt GTTTCCGGCCTTAAAGGCATTCCGCCCTTCCCTTTAAGACGCACCGCCCCCTCTCAGTCACTCCCAAGATGGCGGACCTACTGGGCTCCA TCCTGAGCTCCATGGAGAAGCCACCCAGCCTCGGTGACCAGGAGACTCGGCGCAAGGCCCGAGGATCTTGGTGATGAACTCTTATTTGCC AAGCCAAATATCTTCTGCCACTTTGCTCAAGGGATTGGCGATCCCAAATATGTTCCTGTAACCGACATGGCTCCTCTGAACAAGCTCCTC GTGGACGTCCTGGACAGCTACAATGAAGTTAATGCAGTCATGAATTTGGTGCTGTTTGAGGACGCCGTGGCTCACATCTGCAGGATTAAT CGCATCCTGGAGTCTCCCCGGGGGAATGCCCTGCTGGTGGGGGTGGGCGGCAGTGGCAAACAGAGCCTCTCCCGCCTGGCAGCGTACATC AGCGGGCTTGACGTGTTTCAGATCACCCTCAAGAAGGGCTACGGGATCCCCGACCTCAAGATTGACCTCGCTGCTCAGTACATAAAGGCT GCCGTGAAGAACGTTCCCTCGGTGTTCCTGATGACAGACTCCCAGGTGGCCGAGGAGCAGTTTCTGGTGCTGATCAATGACCTGCTGGCC TCAGGAGAGATCCCTGGGCTGTTTATGGAGGACGAGGTGGAGAACATCATCTCCTCCATGCGACCCCAAGTCAAGTCCCTTGGCATGAAT GACACTCGGGAAACATGTTGGAAGTTCTTCATCGAAAAAGTGCGCAGACAGCTCAAGGTGATCCTGTGTTTCTCCCCTGTGGGCTCCGTG CTGCGGGTACGAGCCAGAAAGTTCCCAGCTGTGGTCAACTGCACGGCCATCGACTGGTTCCACGAGTGGCCGGAAGATGCGCTGGTGTCC GTCAGCGCCCGCTTCCTGGAGGAGACTGAGGGGATTCCGTGGGAAGTCAAGGCCTCCATCAGCTTCTTCATGTCCTACGTGCACACCACC GTCAACGAGATGTCCAGGGTATACCTGGCTACTGAGAGGCGCTACAACTACACCACACCCAAAACCTTTCTGGAGCAGATCAAACTGTAC CAGAACCTGCTGGCCAAGAAGAGAACGGAACTTGTTGCCAAAATCGAGAGGCTGGAGAACGGCCTGATGAAGCTGCAGAGCACGGCTTCC CAGGTGGATGATTTGAAAGCCAAGTTGGCGATTCAGGAGGCTGAGCTCAAGCAGAAGAATGAGAGCGCAGACCAACTGATCCAGGTGGTC GGCATCGAGGCCGAGAAGGTCAGCAAAGAGAAGGCCATTGCTGACCAGGAAGAAGTCAAGGTCGAGGTCATCAATAAGAACGTCACTGAG AAGCAAAAGGCCTGTGAAACAGACCTGGCCAAAGCAGAACCGGCCCTGCTGGCAGCCCAGGAGGCTCTGGACACTCTGAATAAGAACAAC CTGACAGAGCTGAAGTCCTTTGGGTCCCCGCCGGATGCTGTGGTCAACGTCACCGCCGCCGTCATGATTCTGACCGCACCTGGGGGCAAG ATCCCCAAGGACAAGAGCTGGAAGGCGGCCAAGATCATGATGGGCAAGGTGGACACCTTCCTAGACTCCCTGAAGAAGTTCGACAAGGAG CACATCCCTGAGGCCTGCCTGAAGGCCTTCAAGCCCTACCAAGGCAACCCGACGTTCGACCCCGAGTTCATCCGCTCCAAGTCCACGGCC GCCGCCGGCCTGTGCTCCTGGTGCATCAACATCGTCCGCTTCTACGAGGTCTACTGCGACGTGGCGCCCAAGAGGCAGGCACTGGAGGAG GCTAATGCAGAGCTGGCAGAGGCACAAGAGAAGCTGTCCCGGATCAAAAACAAGATTGCCGAACTTAACGCCAACCTGAGCAACCTAACC TCAGCGTTTGAAAAAGCAACAGCTGAGAAAATCAAGTGTCAGCAAGAGGCCGATGCCACGAACAGGGTGATCTTACTGGCGAACAGGCTG GTCGGGGGATTAGCATCGGAAAACATCCGCTGGGCTGAGTCTGTGGAGAACTTCAGGAGCCAGGGGGTCACGCTGTGTGGGGACGTCCTG CTCATCTCTGCCTTCGTGTCCTACGTGGGCTACTTCACCAAGAAATACCGGAATGAGCTGATGGAGAAATTCTGGATCCCTTACATACAT AACTTAAAGGTCCCCATCCCGATCACGAATGGCCTGGATCCCTTGAGCCTGCTGACAGATGACGCGGACGTGGCCACCTGGAACAACCAG GGCCTCCCCAGCGACCGCATGTCCACCGAGAATGCCACCATCCTGGGCAACACCGAGCGGTGGCCGCTGATCGTGGACGCCCAGCTCCAA GGAATCAAGTGGATCAAAAACAAATACAGGAGTGAACTGAAAGCCATCCGCCTGGGACAGAAGAGCTACCTGGATGTCATCGAGCAGGCC ATCTCGGAAGGGGACACCTTGCTCATTGAGAACATCGGCGAAACCGTGGACCCCGTGCTGGACCCTCTACTGGGCAGGAACACGATTAAA AAGGGAAAGTACATTAAGATCGGTGACAAGGAGGTGGAGTACCACCCCAAGTTCCGCCTGATCCTACACACCAAGTACTTCAACCCACAC TACAAGCCAGAGATGCAGGCTCAGTGCACCCTCATCAACTTCCTGGTCACCAGGGATGGACTCGAGGACCAACTCTTGGCCGCTGTGGTG GCCAAAGAGCGCCCAGATCTGGAACAGCTGAAGGCAAACCTCACCAAGTCTCAAAACGAATTTAAGATTGTTCTGAAAGAGCTGGAAGAT TCGCTCCTGGCCCGTCTGTCGGCTGCGTCGGGGAACTTTCTGGGAGACACGGCCTTGGTGGAGAATCTGGAGACCACCAAGCACACAGCC AGCGAGATCGAGGAGAAGGTGGTGGAGGCAAAAATCACAGAAGTTAAAATCAACGAAGCGAGAGAGAACTACCGCCCGGCTGCGGAGAGG GCATCTCTGCTCTACTTCATACTGAACGATCTCAACAAAATCAACCCCGTCTACCAGTTCTCCCTCAAGGCCTTCAACGTGGTGTTTGAG AAAGCCATCCAGAGGACCACCCCTGCCAACGAGGTGAAGCAGCGGGTGATCAACCTGACGGACGAGATCACCTACTCCGTCTACATGTAC ACGGCCCGGGGACTCTTCGAGAGGGACAAACTCATTTTCCTGGCACAAGTTACGTTTCAGGTCCTGTCCATGAAGAAGGAGCTGAACCCA GTGGAGCTGGATTTCCTCCTGCGGTTCCCTTTTAAGGCCGGAGTGGTCTCACCAGTGGACTTCCTCCAGCATCAAGGCTGGGGCGGGATC AAGGCCCTCTCGGAGATGGATGAGTTCAAAAATCTGGACAGTGACATCGAAGGATCTGCCAAGCGCTGGAAAAAGCTGGTGGAGTCGGAA GCCCCCGAGAAGGAGATCTTCCCCAAGGAGTGGAAGAACAAGACGGCCCTGCAGAAGCTGTGCATGGTGCGCTGCCTGCGGCCAGATCGC ATGACCTACGCTATCAAGAACTTCGTGGAGGAAAAGATGGGCAGCAAGTTCGTGGAAGGCCGGAGTGTTGAGTTTTCTAAGTCCTACGAG GAGAGCAGCCCCTCCACGTCAATCTTCTTCATCCTCTCCCCGGGGGTTGACCCCTTGAAAGACGTGGAAGCCCTGGGAAAAAAACTAGGG TTTACCATAGACAATGGAAAACTCCATAATGTGTCCCTGGGGCAGGGACAAGAGGTGGTGGCTGAGAACGCCCTGGACGTGGCTGCAGAG AAAGGACACTGGGTCATTCTGCAGAATATCCACCTGGTGGCCCGGTGGCTGGGAACACTGGACAAGAAGCTGGAGCACTACAGCACGGGC AGCCATGAGGACTACCGGGTGTTCATCAGCGCGGAGCCTGCCCCCAGCCCCGAGACCCACATCATCCCCCAGGGCATTCTGGAGAACGCC ATCAAGATCACCAACGAGCCCCCCACGGGCATGCACGCCAACTTGCACAAGGCCCTGGACCTGTTCACCCAGGACACCCTGGAGATGTGC ACCAAGGAGATGGAGTTCAAGTGCATGCTCTTCGCCCTGTGCTACTTCCACGCTGTGGTGGCAGAGAGGCGCAAGTTCGGCGCCCAGGGC TGGAACCGGTCGTACCCCTTCAACAACGGGGACCTCACCATCTCCATCAACGTGCTCTACAACTACCTGGAGGCCAACCCCAAGGTGCCC TGGGACGATCTCCGCTACCTTTTTGGTGAAATCATGTATGGCGGCCACATCACAGATGACTGGGACCGTCGGCTGTGCAGGACCTACCTG GCTGAATACATCCGGACGGAGATGCTGGAGGGAGACGTCCTGCTGGCCCCCGGCTTTCAGATCCCCCCCAACCTGGACTACAAGGGTTAC CACGAATACATCGATGAGAACCTGCCCCCTGAGAGTCCCTATCTGTATGGCCTGCACCCCAACGCAGAGATTGGCTTTCTGACGGTCACC TCAGAGAAGCTGTTCCGCACTGTCCTGGAAATGCAGCCAAAAGAGACGGACTCGGGGGCAGGCACGGGAGTGTCCCGCGAGGAGAAGGTG AAGGCCGTGCTGGACGACATCCTGGAGAAGATTCCGGAGACTTTCAACATGGCTGAGATCATGGCAAAGGCAGCGGAAAAGACCCCCTAC GTGGTAGTCGCCTTTCAAGAATGTGAAAGAATGAACATCCTGACCAACGAAATGCGCCGTTCGCTCAAGGAGCTGAACCTGGGGCTGAAG GGAGAACTGACCATCACGACCGACGTGGAAGATCTGTCCACGGCTCTCTTCTATGACACCGTGCCTGATACGTGGGTGGCCCGGGCCTAC CCCTCCATGATGGGCCTGGCGGCCTGGTACGCAGACCTGCTGCTCCGCATCAGGGAACTCGAGGCCTGGACGACAGACTTTGCCCTGCCC ACCACCGTGTGGCTGGCCGGCTTCTTCAACCCCCAGTCGTTCCTCACGGCCATCATGCAGTCCATGGCCAGGAAGAACGAGTGGCCCCTG GACAAGATGTGTCTGTCTGTCGAGGTGACCAAGAAAAACCGAGAGGACATGACCGCTCCTCCGCGAGAGGGCTCCTACGTGTACGGACTC TTCATGGAAGGGGCTCGCTGGGACACCCAGACTGGAGTCATCGCTGAAGCGCGGCTGAAAGAGCTGACCCCGGCCATGCCTGTCATCTTC ATCAAGGCCATTCCTGTGGACCGCATGGAGACCAAGAACATCTATGAGTGTCCCGTGTACAAAACACGCATCCGCGGCCCCACCTATGTC TGGACCTTTAACTTGAAGACCAAAGAGAAGGCAGCGAAGTGGATCCTGGCAGCCGTGGCGCTGCTCCTACAGGTTTAGCTCGCTCCTGCC TCACAGCCCACACTCCCTGGGGCTGGACCACAACTCAGCCCTTCACCTGTGCACCTGTGACTTATTCTTTACAGGAACTGGTGGTGGTTT TTCGTTCTCTTAAATAATCAGGTGCTTTGTAACCAAGCACATCGGAACCAGAGGGTGGAGGTTGGTGTGGAAGAGGTGGGGCAGATTAAA >In-frame_ENST00000206020_ENST00000585328_TCGA-P3-A5QE-01A_SPAG7_chr17_4871015_-_DNAH17_chr17_76471915_length(amino acids)=1713AA_start in transcript=246_stop in transcript=5387 MAPLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKID LAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVIL CFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPWEVKASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKT FLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVE VINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLD SLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAEL NANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELME KFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQKS YLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLE DQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARE NYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVL SMKKELNPVELDFLLRFPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCM VRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAE NALDVAAEKGHWVILQNIHLVARWLGTLDKKLEHYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLF TQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWD RRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGT GVSREEKVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVP DTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPR EGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKWILAAVALL -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for SPAG7-DNAH17 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for SPAG7-DNAH17 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for SPAG7-DNAH17 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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