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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SPOP-NBPF1 (FusionGDB2 ID:85358)

Fusion Gene Summary for SPOP-NBPF1

check button Fusion gene summary
Fusion gene informationFusion gene name: SPOP-NBPF1
Fusion gene ID: 85358
HgeneTgene
Gene symbol

SPOP

NBPF1

Gene ID

8405

55672

Gene namespeckle type BTB/POZ proteinNBPF member 1
SynonymsBTBD32|TEF2AB13|AB14|AB23|AD2|NBG|NBPF
Cytomap

17q21.33

1p36.13

Type of geneprotein-codingprotein-coding
Descriptionspeckle-type POZ proteinHIB homolog 1roadkill homolog 1neuroblastoma breakpoint family member 1
Modification date2020032920200313
UniProtAcc.

A0A087WUL8

Ensembl transtripts involved in fusion geneENST00000393328, ENST00000393331, 
ENST00000347630, ENST00000504102, 
ENST00000503676, ENST00000513080, 
ENST00000430580, ENST00000420031, 
ENST00000432949, ENST00000287968, 
ENST00000599908, 
Fusion gene scores* DoF score37 X 22 X 16=130242 X 2 X 2=8
# samples 463
** MAII scorelog2(46/13024*10)=-4.82339493332187
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/8*10)=1.90689059560852
Context

PubMed: SPOP [Title/Abstract] AND NBPF1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSPOP(47688642)-NBPF1(16890681), # samples:2
Anticipated loss of major functional domain due to fusion event.SPOP-NBPF1 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
SPOP-NBPF1 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
SPOP-NBPF1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
SPOP-NBPF1 seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across SPOP (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across NBPF1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LGGTCGA-QH-A6CV-01ASPOPchr17

47688642

-NBPF1chr1

16890681

-
ChimerDB4LGGTCGA-QH-A6CVSPOPchr17

47688641

-NBPF1chr1

16890681

-
ChimerDB4LGGTCGA-QH-A6CVSPOPchr17

47688642

-NBPF1chr1

16890681

-


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Fusion Gene ORF analysis for SPOP-NBPF1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000393328ENST00000430580SPOPchr17

47688642

-NBPF1chr1

16890681

-
5CDS-intronENST00000393328ENST00000420031SPOPchr17

47688642

-NBPF1chr1

16890681

-
5CDS-intronENST00000393328ENST00000432949SPOPchr17

47688642

-NBPF1chr1

16890681

-
5CDS-intronENST00000393328ENST00000287968SPOPchr17

47688642

-NBPF1chr1

16890681

-
5CDS-intronENST00000393328ENST00000599908SPOPchr17

47688642

-NBPF1chr1

16890681

-
Frame-shiftENST00000393331ENST00000430580SPOPchr17

47688642

-NBPF1chr1

16890681

-
5CDS-intronENST00000393331ENST00000420031SPOPchr17

47688642

-NBPF1chr1

16890681

-
5CDS-intronENST00000393331ENST00000432949SPOPchr17

47688642

-NBPF1chr1

16890681

-
5CDS-intronENST00000393331ENST00000287968SPOPchr17

47688642

-NBPF1chr1

16890681

-
5CDS-intronENST00000393331ENST00000599908SPOPchr17

47688642

-NBPF1chr1

16890681

-
Frame-shiftENST00000347630ENST00000430580SPOPchr17

47688642

-NBPF1chr1

16890681

-
5CDS-intronENST00000347630ENST00000420031SPOPchr17

47688642

-NBPF1chr1

16890681

-
5CDS-intronENST00000347630ENST00000432949SPOPchr17

47688642

-NBPF1chr1

16890681

-
5CDS-intronENST00000347630ENST00000287968SPOPchr17

47688642

-NBPF1chr1

16890681

-
5CDS-intronENST00000347630ENST00000599908SPOPchr17

47688642

-NBPF1chr1

16890681

-
Frame-shiftENST00000504102ENST00000430580SPOPchr17

47688642

-NBPF1chr1

16890681

-
5CDS-intronENST00000504102ENST00000420031SPOPchr17

47688642

-NBPF1chr1

16890681

-
5CDS-intronENST00000504102ENST00000432949SPOPchr17

47688642

-NBPF1chr1

16890681

-
5CDS-intronENST00000504102ENST00000287968SPOPchr17

47688642

-NBPF1chr1

16890681

-
5CDS-intronENST00000504102ENST00000599908SPOPchr17

47688642

-NBPF1chr1

16890681

-
In-frameENST00000503676ENST00000430580SPOPchr17

47688642

-NBPF1chr1

16890681

-
5CDS-intronENST00000503676ENST00000420031SPOPchr17

47688642

-NBPF1chr1

16890681

-
5CDS-intronENST00000503676ENST00000432949SPOPchr17

47688642

-NBPF1chr1

16890681

-
5CDS-intronENST00000503676ENST00000287968SPOPchr17

47688642

-NBPF1chr1

16890681

-
5CDS-intronENST00000503676ENST00000599908SPOPchr17

47688642

-NBPF1chr1

16890681

-
intron-3CDSENST00000513080ENST00000430580SPOPchr17

47688642

-NBPF1chr1

16890681

-
intron-intronENST00000513080ENST00000420031SPOPchr17

47688642

-NBPF1chr1

16890681

-
intron-intronENST00000513080ENST00000432949SPOPchr17

47688642

-NBPF1chr1

16890681

-
intron-intronENST00000513080ENST00000287968SPOPchr17

47688642

-NBPF1chr1

16890681

-
intron-intronENST00000513080ENST00000599908SPOPchr17

47688642

-NBPF1chr1

16890681

-
In-frameENST00000393328ENST00000430580SPOPchr17

47688641

-NBPF1chr1

16890681

-
5CDS-intronENST00000393328ENST00000420031SPOPchr17

47688641

-NBPF1chr1

16890681

-
5CDS-intronENST00000393328ENST00000432949SPOPchr17

47688641

-NBPF1chr1

16890681

-
5CDS-intronENST00000393328ENST00000287968SPOPchr17

47688641

-NBPF1chr1

16890681

-
5CDS-intronENST00000393328ENST00000599908SPOPchr17

47688641

-NBPF1chr1

16890681

-
Frame-shiftENST00000393331ENST00000430580SPOPchr17

47688641

-NBPF1chr1

16890681

-
5CDS-intronENST00000393331ENST00000420031SPOPchr17

47688641

-NBPF1chr1

16890681

-
5CDS-intronENST00000393331ENST00000432949SPOPchr17

47688641

-NBPF1chr1

16890681

-
5CDS-intronENST00000393331ENST00000287968SPOPchr17

47688641

-NBPF1chr1

16890681

-
5CDS-intronENST00000393331ENST00000599908SPOPchr17

47688641

-NBPF1chr1

16890681

-
Frame-shiftENST00000347630ENST00000430580SPOPchr17

47688641

-NBPF1chr1

16890681

-
5CDS-intronENST00000347630ENST00000420031SPOPchr17

47688641

-NBPF1chr1

16890681

-
5CDS-intronENST00000347630ENST00000432949SPOPchr17

47688641

-NBPF1chr1

16890681

-
5CDS-intronENST00000347630ENST00000287968SPOPchr17

47688641

-NBPF1chr1

16890681

-
5CDS-intronENST00000347630ENST00000599908SPOPchr17

47688641

-NBPF1chr1

16890681

-
Frame-shiftENST00000504102ENST00000430580SPOPchr17

47688641

-NBPF1chr1

16890681

-
5CDS-intronENST00000504102ENST00000420031SPOPchr17

47688641

-NBPF1chr1

16890681

-
5CDS-intronENST00000504102ENST00000432949SPOPchr17

47688641

-NBPF1chr1

16890681

-
5CDS-intronENST00000504102ENST00000287968SPOPchr17

47688641

-NBPF1chr1

16890681

-
5CDS-intronENST00000504102ENST00000599908SPOPchr17

47688641

-NBPF1chr1

16890681

-
In-frameENST00000503676ENST00000430580SPOPchr17

47688641

-NBPF1chr1

16890681

-
5CDS-intronENST00000503676ENST00000420031SPOPchr17

47688641

-NBPF1chr1

16890681

-
5CDS-intronENST00000503676ENST00000432949SPOPchr17

47688641

-NBPF1chr1

16890681

-
5CDS-intronENST00000503676ENST00000287968SPOPchr17

47688641

-NBPF1chr1

16890681

-
5CDS-intronENST00000503676ENST00000599908SPOPchr17

47688641

-NBPF1chr1

16890681

-
intron-3CDSENST00000513080ENST00000430580SPOPchr17

47688641

-NBPF1chr1

16890681

-
intron-intronENST00000513080ENST00000420031SPOPchr17

47688641

-NBPF1chr1

16890681

-
intron-intronENST00000513080ENST00000432949SPOPchr17

47688641

-NBPF1chr1

16890681

-
intron-intronENST00000513080ENST00000287968SPOPchr17

47688641

-NBPF1chr1

16890681

-
intron-intronENST00000513080ENST00000599908SPOPchr17

47688641

-NBPF1chr1

16890681

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000393328SPOPchr1747688642-ENST00000430580NBPF1chr116890681-289210243601040226
ENST00000503676SPOPchr1747688642-ENST00000430580NBPF1chr116890681-315812906261306226
ENST00000393328SPOPchr1747688641-ENST00000430580NBPF1chr116890681-289210243601040226
ENST00000503676SPOPchr1747688641-ENST00000430580NBPF1chr116890681-315812906261306226

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000393328ENST00000430580SPOPchr1747688642-NBPF1chr116890681-0.0010431560.9989568
ENST00000503676ENST00000430580SPOPchr1747688642-NBPF1chr116890681-0.0009875280.9990125
ENST00000393328ENST00000430580SPOPchr1747688641-NBPF1chr116890681-0.0010431560.9989568
ENST00000503676ENST00000430580SPOPchr1747688641-NBPF1chr116890681-0.0009875280.9990125

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Fusion Genomic Features for SPOP-NBPF1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for SPOP-NBPF1


check button Go to

FGviewer for the breakpoints of chr17:47688642-chr1:16890681

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.NBPF1

A0A087WUL8

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSPOPchr17:47688641chr1:16890681ENST00000347630-71131_161219.33333333333334375.0DomainMATH
HgeneSPOPchr17:47688641chr1:16890681ENST00000393328-71131_161219.33333333333334375.0DomainMATH
HgeneSPOPchr17:47688641chr1:16890681ENST00000393331-81231_161219.33333333333334375.0DomainMATH
HgeneSPOPchr17:47688641chr1:16890681ENST00000503676-71131_161219.33333333333334375.0DomainMATH
HgeneSPOPchr17:47688641chr1:16890681ENST00000504102-61031_161219.33333333333334375.0DomainMATH
HgeneSPOPchr17:47688642chr1:16890681ENST00000347630-71131_161219.33333333333334375.0DomainMATH
HgeneSPOPchr17:47688642chr1:16890681ENST00000393328-71131_161219.33333333333334375.0DomainMATH
HgeneSPOPchr17:47688642chr1:16890681ENST00000393331-81231_161219.33333333333334375.0DomainMATH
HgeneSPOPchr17:47688642chr1:16890681ENST00000503676-71131_161219.33333333333334375.0DomainMATH
HgeneSPOPchr17:47688642chr1:16890681ENST00000504102-61031_161219.33333333333334375.0DomainMATH
HgeneSPOPchr17:47688641chr1:16890681ENST00000347630-711123_133219.33333333333334375.0RegionNote=Important for binding substrate proteins
HgeneSPOPchr17:47688641chr1:16890681ENST00000347630-711186_217219.33333333333334375.0RegionNote=Important for homodimerization
HgeneSPOPchr17:47688641chr1:16890681ENST00000347630-71171_191219.33333333333334375.0RegionNote=Required for nuclear localization
HgeneSPOPchr17:47688641chr1:16890681ENST00000393328-711123_133219.33333333333334375.0RegionNote=Important for binding substrate proteins
HgeneSPOPchr17:47688641chr1:16890681ENST00000393328-711186_217219.33333333333334375.0RegionNote=Important for homodimerization
HgeneSPOPchr17:47688641chr1:16890681ENST00000393328-71171_191219.33333333333334375.0RegionNote=Required for nuclear localization
HgeneSPOPchr17:47688641chr1:16890681ENST00000393331-812123_133219.33333333333334375.0RegionNote=Important for binding substrate proteins
HgeneSPOPchr17:47688641chr1:16890681ENST00000393331-812186_217219.33333333333334375.0RegionNote=Important for homodimerization
HgeneSPOPchr17:47688641chr1:16890681ENST00000393331-81271_191219.33333333333334375.0RegionNote=Required for nuclear localization
HgeneSPOPchr17:47688641chr1:16890681ENST00000503676-711123_133219.33333333333334375.0RegionNote=Important for binding substrate proteins
HgeneSPOPchr17:47688641chr1:16890681ENST00000503676-711186_217219.33333333333334375.0RegionNote=Important for homodimerization
HgeneSPOPchr17:47688641chr1:16890681ENST00000503676-71171_191219.33333333333334375.0RegionNote=Required for nuclear localization
HgeneSPOPchr17:47688641chr1:16890681ENST00000504102-610123_133219.33333333333334375.0RegionNote=Important for binding substrate proteins
HgeneSPOPchr17:47688641chr1:16890681ENST00000504102-610186_217219.33333333333334375.0RegionNote=Important for homodimerization
HgeneSPOPchr17:47688641chr1:16890681ENST00000504102-61071_191219.33333333333334375.0RegionNote=Required for nuclear localization
HgeneSPOPchr17:47688642chr1:16890681ENST00000347630-711123_133219.33333333333334375.0RegionNote=Important for binding substrate proteins
HgeneSPOPchr17:47688642chr1:16890681ENST00000347630-711186_217219.33333333333334375.0RegionNote=Important for homodimerization
HgeneSPOPchr17:47688642chr1:16890681ENST00000347630-71171_191219.33333333333334375.0RegionNote=Required for nuclear localization
HgeneSPOPchr17:47688642chr1:16890681ENST00000393328-711123_133219.33333333333334375.0RegionNote=Important for binding substrate proteins
HgeneSPOPchr17:47688642chr1:16890681ENST00000393328-711186_217219.33333333333334375.0RegionNote=Important for homodimerization
HgeneSPOPchr17:47688642chr1:16890681ENST00000393328-71171_191219.33333333333334375.0RegionNote=Required for nuclear localization
HgeneSPOPchr17:47688642chr1:16890681ENST00000393331-812123_133219.33333333333334375.0RegionNote=Important for binding substrate proteins
HgeneSPOPchr17:47688642chr1:16890681ENST00000393331-812186_217219.33333333333334375.0RegionNote=Important for homodimerization
HgeneSPOPchr17:47688642chr1:16890681ENST00000393331-81271_191219.33333333333334375.0RegionNote=Required for nuclear localization
HgeneSPOPchr17:47688642chr1:16890681ENST00000503676-711123_133219.33333333333334375.0RegionNote=Important for binding substrate proteins
HgeneSPOPchr17:47688642chr1:16890681ENST00000503676-711186_217219.33333333333334375.0RegionNote=Important for homodimerization
HgeneSPOPchr17:47688642chr1:16890681ENST00000503676-71171_191219.33333333333334375.0RegionNote=Required for nuclear localization
HgeneSPOPchr17:47688642chr1:16890681ENST00000504102-610123_133219.33333333333334375.0RegionNote=Important for binding substrate proteins
HgeneSPOPchr17:47688642chr1:16890681ENST00000504102-610186_217219.33333333333334375.0RegionNote=Important for homodimerization
HgeneSPOPchr17:47688642chr1:16890681ENST00000504102-61071_191219.33333333333334375.0RegionNote=Required for nuclear localization

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSPOPchr17:47688641chr1:16890681ENST00000347630-711173_297219.33333333333334375.0DomainBTB
HgeneSPOPchr17:47688641chr1:16890681ENST00000393328-711173_297219.33333333333334375.0DomainBTB
HgeneSPOPchr17:47688641chr1:16890681ENST00000393331-812173_297219.33333333333334375.0DomainBTB
HgeneSPOPchr17:47688641chr1:16890681ENST00000503676-711173_297219.33333333333334375.0DomainBTB
HgeneSPOPchr17:47688641chr1:16890681ENST00000504102-610173_297219.33333333333334375.0DomainBTB
HgeneSPOPchr17:47688642chr1:16890681ENST00000347630-711173_297219.33333333333334375.0DomainBTB
HgeneSPOPchr17:47688642chr1:16890681ENST00000393328-711173_297219.33333333333334375.0DomainBTB
HgeneSPOPchr17:47688642chr1:16890681ENST00000393331-812173_297219.33333333333334375.0DomainBTB
HgeneSPOPchr17:47688642chr1:16890681ENST00000503676-711173_297219.33333333333334375.0DomainBTB
HgeneSPOPchr17:47688642chr1:16890681ENST00000504102-610173_297219.33333333333334375.0DomainBTB
HgeneSPOPchr17:47688641chr1:16890681ENST00000347630-711297_355219.33333333333334375.0RegionNote=Important for homodimerization
HgeneSPOPchr17:47688641chr1:16890681ENST00000393328-711297_355219.33333333333334375.0RegionNote=Important for homodimerization
HgeneSPOPchr17:47688641chr1:16890681ENST00000393331-812297_355219.33333333333334375.0RegionNote=Important for homodimerization
HgeneSPOPchr17:47688641chr1:16890681ENST00000503676-711297_355219.33333333333334375.0RegionNote=Important for homodimerization
HgeneSPOPchr17:47688641chr1:16890681ENST00000504102-610297_355219.33333333333334375.0RegionNote=Important for homodimerization
HgeneSPOPchr17:47688642chr1:16890681ENST00000347630-711297_355219.33333333333334375.0RegionNote=Important for homodimerization
HgeneSPOPchr17:47688642chr1:16890681ENST00000393328-711297_355219.33333333333334375.0RegionNote=Important for homodimerization
HgeneSPOPchr17:47688642chr1:16890681ENST00000393331-812297_355219.33333333333334375.0RegionNote=Important for homodimerization
HgeneSPOPchr17:47688642chr1:16890681ENST00000503676-711297_355219.33333333333334375.0RegionNote=Important for homodimerization
HgeneSPOPchr17:47688642chr1:16890681ENST00000504102-610297_355219.33333333333334375.0RegionNote=Important for homodimerization


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Fusion Gene Sequence for SPOP-NBPF1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000393328_ENST00000430580_TCGA-QH-A6CV-01A_SPOP_chr17_47688642_-_NBPF1_chr1_16890681_length(transcript)=2892nt_BP=1024nt
GTGCTGACGCCATGACGCCCCGGCTGGTGTGTGTCGGTGTGTATGTGTGTGTGTGAGTGTGCGCGCTCCGAGTGTGTGTGTATTTGTGTA
TCGGCGGTCCCGCAGGTCCCGGATGTTGCGGACAGTATGAGGCAAGCGCAGGGGGACGGGGACCAGCAGCTGTCGCCGCCGCTCTCAGAT
CGAGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGCGATCTCAGCTCACTGCCACCTTTGCCTCCTGGGTTCAAGCGATTCTTCTG
CCTCAGCCTCCCGAGTAGCTGGGATTACAGGGTGAAGAGGGAACAGAAATCTTTGCCCCCTGACTTTGGAAATCTCGTTTAACCTTCAAA
CTGGCGATGTCAAGGGTTCCAAGTCCTCCACCTCCGGCAGAAATGTCGAGTGGCCCCGTAGCTGAGAGTTGGTGCTACACACAGATCAAG
GTAGTGAAATTCTCCTACATGTGGACCATCAATAACTTTAGCTTTTGCCGGGAGGAAATGGGTGAAGTCATTAAAAGTTCTACATTTTCA
TCAGGAGCAAATGATAAACTGAAATGGTGTTTGCGAGTAAACCCCAAAGGGTTAGATGAAGAAAGCAAAGATTACCTGTCACTTTACCTG
TTACTGGTCAGCTGTCCAAAGAGTGAAGTTCGGGCAAAATTCAAATTCTCCATCCTGAATGCCAAGGGAGAAGAAACCAAAGCTATGGAG
AGTCAACGGGCATATAGGTTTGTGCAAGGCAAAGACTGGGGATTCAAGAAATTCATCCGTAGAGATTTTCTTTTGGATGAGGCCAACGGG
CTTCTCCCTGATGACAAGCTTACCCTCTTCTGCGAGGTGAGTGTTGTGCAAGATTCTGTCAACATTTCTGGCCAGAATACCATGAACATG
GTAAAGGTTCCTGAGTGCCGGCTGGCAGATGAGTTAGGAGGACTGTGGGAGAATTCCCGGTTCACAGACTGCTGCTTGTGTGTTGCCGGC
CAGGAATTCCAGGCTCACAAGGCTATCTTAGCAGGCTCAGCGGCATGCTGATGGAAGTGGAAGAGCCTGAAGTCTTGCAGGACTCACTGG
ATAGATGTTATTCGACTCCGTCAATGTACTTTGAACTACCTGACTCATTCCAGCACTACAGAAGTGTGTTTTACTCATTTGAGGAACAGC
ACATCAGCTTCGCCCTTGACGTGGACAATAGGTTTCTTACTTTGATGGGAACAAGTCTCCACCTGGTCTTCCAGATGGGAGTCATATTCC
CACAGTAAGCAGCCCTTACTAAGCCGAGAGATGTCATTCCTGCAGGCAGGACCTATAGGCACGTGAAGATTTGAATGAAACTATAGTTCC
ATTTGGAAGCCCAGACATAGGATGGGTCAGTGGGCATGGCTCTATTCCTATTCTCAGACCATGCCAGTGGCACCCTGTGCTCAGTCTGAA
GACAATGGACCCAAGTTAGGTGTGACACGTTCACATAACTGTGCAGCACATGCCGGGAGTGATCAGTCAGACATTTTAATTTGAACCACT
TATCTCTGGGTAGCTACAAAGTTCCTCAGGGATTTCATTTTGCAGTCATGTCTCTGAGCTTCTATACCTGCTCAAGGTCAGTGTCATCTT
TGTGTTTAGCTCATCCAAAGGTGTTACCCTGGTTTCAATGAACCTAACCTCATTCTTTGTATCTTCAGTGTTGAATTGTTTTAGCTGATC
CATCTTTAACACAGGAGGGATCCTTGGCTGAGGATTGTATTTCAGAACCACCAACTGCTCTTGACAATTGTTAACCCGCTAGGCTCCTTT
GGTTAGAGAAGCCACAGTCCTTCAGCCTCCAATTGGTGTCAGTACTTAGGAAGACCACAGCTAGATGGACAAACAGCATTGGGAGGCCTT
AGCCCTGCTCCTCTCGATTCCATCCTGTAGAGAACAGGAGTCAGGAGCCGCTGGCAGGAGACAGCATGTCACCCAGGACTCTGCCGGTGC
AGAATATGAACAACGCCATGTTCTTGCAGAAAACGCTTAGCCTGAGTTTCATAGGAGGTAATTACCAGACAACTGCAGAATGTAGAACAC
TGAGCAGGACAACTGACCTGTCTCCTTCACATAGTCCATATCACCACAAATCACACAACAAAAAGGAGAAGAGATATTTTGGGTTCAAAA
AAAGTAAAAAGATAATATAGCTGCATTTCTTTAGTTATTTTGAACCCCAAATATTTCCTCATCTTTTTGTTGTTGTCATTGATGGTGGTG
ACATGGACTTGTTTATAGAGGACAGGTCAGCTCTCTGGCTCAATGATCTACATTCTGAAGTTGTCTGAAAATGTCTTCATGATTAAATTC
AGCCTAAACGTTTTGCCGGGAACACTGCAGAGACAATGCTGTGAGTTTCCAACCTTAGCCCATCTGCGGGCAGAGAAGGTCTAGTTTGTC
CATCAGCATTATCATGATATCAGGACTGGTTACTTGGTTAAGGAGGGGTCTAGGAGATCTGTCCCTTTTAGAGACACCTTACTTATAATG
AAGTATTTGGGAGGGTGGTTTTCAAAATTAGAAATGTCCTGTATTCCAATGATCATCCTGTAAACATTTTATCATTTATTAATCATCCCT
GCCTGTGTCTATTATTATATTCATATCTCTACGCTGGAAACTTTCTGCCTCAATGTTTACTGTGCCTTTGTTTTTGCTAGTGTGTGTTGT
TGAAAAAAAAAACATTCTCTGCCTGAGTTTTAATTTTTGTCCAAAGTTATTTTAATCTATACAATTAAAAGCTTTTGCCTATCACTCTGG
ACTGTTGGATTGTTTTTTACATTCAGTGTTATAATCTTTTGTTATGCTGATTGGTTTTGGTGGGTACTGATGTGAATTAATAAAAACATT

>In-frame_ENST00000393328_ENST00000430580_TCGA-QH-A6CV-01A_SPOP_chr17_47688642_-_NBPF1_chr1_16890681_length(amino acids)=226AA_start in transcript=360_stop in transcript=1040
MAMSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYL
LLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNM

--------------------------------------------------------------
>In-frame_ENST00000503676_ENST00000430580_TCGA-QH-A6CV-01A_SPOP_chr17_47688642_-_NBPF1_chr1_16890681_length(transcript)=3158nt_BP=1290nt
ATATAGCTTAAAGCATTTAACTGGAAAGGACCTTGGAAATCCTTTTAAAGGAGGATGGGGGTGGAAATGCACAGGTTGCTTCTCTCTCTC
TCTCTCTTTTTTTTTTTTTTTGAGACGGTCACCCAGGCTGTAGTGCAGTGGCGTGATCTCGGCTCACTGTGGCCTCCACCTCCCAAGTAG
CTGGGATTACAGGCTTGCGCCATCATGCAGGGCTAATTTTTGTATTTTTAGTAGAGACGAGGTTTCATCATGTTGGCCAGGCTGGTCTGG
AACTCCTGACCTCAAGTGATCTGCCCACCTTGGCCTCCCAAAGTGCTGGGATTAAAGGCATGAGCCACCACGCCTGGCCTAGGTTGTTCC
TCTACTGTGAATCTTGAGGTTATGGTTTCCACTAGACTATAGTGCTCAACTATAGTGGCCTATTTTAAGTGGCCTTATAATTCCTAACCA
AAGTGACTTGTGAAACAGAGGACCCTGGATAAATTTAAATGTTATAAAGATGATAAAATGTACAGAGATTTCCTGTTAGACAAGACAAAT
TAGAGTTTTCCTACTGACTTAACTTGGGTGAAGAGGGAACAGAAATCTTTGCCCCCTGACTTTGGAAATCTCGTTTAACCTTCAAACTGG
CGATGTCAAGGGTTCCAAGTCCTCCACCTCCGGCAGAAATGTCGAGTGGCCCCGTAGCTGAGAGTTGGTGCTACACACAGATCAAGGTAG
TGAAATTCTCCTACATGTGGACCATCAATAACTTTAGCTTTTGCCGGGAGGAAATGGGTGAAGTCATTAAAAGTTCTACATTTTCATCAG
GAGCAAATGATAAACTGAAATGGTGTTTGCGAGTAAACCCCAAAGGGTTAGATGAAGAAAGCAAAGATTACCTGTCACTTTACCTGTTAC
TGGTCAGCTGTCCAAAGAGTGAAGTTCGGGCAAAATTCAAATTCTCCATCCTGAATGCCAAGGGAGAAGAAACCAAAGCTATGGAGAGTC
AACGGGCATATAGGTTTGTGCAAGGCAAAGACTGGGGATTCAAGAAATTCATCCGTAGAGATTTTCTTTTGGATGAGGCCAACGGGCTTC
TCCCTGATGACAAGCTTACCCTCTTCTGCGAGGTGAGTGTTGTGCAAGATTCTGTCAACATTTCTGGCCAGAATACCATGAACATGGTAA
AGGTTCCTGAGTGCCGGCTGGCAGATGAGTTAGGAGGACTGTGGGAGAATTCCCGGTTCACAGACTGCTGCTTGTGTGTTGCCGGCCAGG
AATTCCAGGCTCACAAGGCTATCTTAGCAGGCTCAGCGGCATGCTGATGGAAGTGGAAGAGCCTGAAGTCTTGCAGGACTCACTGGATAG
ATGTTATTCGACTCCGTCAATGTACTTTGAACTACCTGACTCATTCCAGCACTACAGAAGTGTGTTTTACTCATTTGAGGAACAGCACAT
CAGCTTCGCCCTTGACGTGGACAATAGGTTTCTTACTTTGATGGGAACAAGTCTCCACCTGGTCTTCCAGATGGGAGTCATATTCCCACA
GTAAGCAGCCCTTACTAAGCCGAGAGATGTCATTCCTGCAGGCAGGACCTATAGGCACGTGAAGATTTGAATGAAACTATAGTTCCATTT
GGAAGCCCAGACATAGGATGGGTCAGTGGGCATGGCTCTATTCCTATTCTCAGACCATGCCAGTGGCACCCTGTGCTCAGTCTGAAGACA
ATGGACCCAAGTTAGGTGTGACACGTTCACATAACTGTGCAGCACATGCCGGGAGTGATCAGTCAGACATTTTAATTTGAACCACTTATC
TCTGGGTAGCTACAAAGTTCCTCAGGGATTTCATTTTGCAGTCATGTCTCTGAGCTTCTATACCTGCTCAAGGTCAGTGTCATCTTTGTG
TTTAGCTCATCCAAAGGTGTTACCCTGGTTTCAATGAACCTAACCTCATTCTTTGTATCTTCAGTGTTGAATTGTTTTAGCTGATCCATC
TTTAACACAGGAGGGATCCTTGGCTGAGGATTGTATTTCAGAACCACCAACTGCTCTTGACAATTGTTAACCCGCTAGGCTCCTTTGGTT
AGAGAAGCCACAGTCCTTCAGCCTCCAATTGGTGTCAGTACTTAGGAAGACCACAGCTAGATGGACAAACAGCATTGGGAGGCCTTAGCC
CTGCTCCTCTCGATTCCATCCTGTAGAGAACAGGAGTCAGGAGCCGCTGGCAGGAGACAGCATGTCACCCAGGACTCTGCCGGTGCAGAA
TATGAACAACGCCATGTTCTTGCAGAAAACGCTTAGCCTGAGTTTCATAGGAGGTAATTACCAGACAACTGCAGAATGTAGAACACTGAG
CAGGACAACTGACCTGTCTCCTTCACATAGTCCATATCACCACAAATCACACAACAAAAAGGAGAAGAGATATTTTGGGTTCAAAAAAAG
TAAAAAGATAATATAGCTGCATTTCTTTAGTTATTTTGAACCCCAAATATTTCCTCATCTTTTTGTTGTTGTCATTGATGGTGGTGACAT
GGACTTGTTTATAGAGGACAGGTCAGCTCTCTGGCTCAATGATCTACATTCTGAAGTTGTCTGAAAATGTCTTCATGATTAAATTCAGCC
TAAACGTTTTGCCGGGAACACTGCAGAGACAATGCTGTGAGTTTCCAACCTTAGCCCATCTGCGGGCAGAGAAGGTCTAGTTTGTCCATC
AGCATTATCATGATATCAGGACTGGTTACTTGGTTAAGGAGGGGTCTAGGAGATCTGTCCCTTTTAGAGACACCTTACTTATAATGAAGT
ATTTGGGAGGGTGGTTTTCAAAATTAGAAATGTCCTGTATTCCAATGATCATCCTGTAAACATTTTATCATTTATTAATCATCCCTGCCT
GTGTCTATTATTATATTCATATCTCTACGCTGGAAACTTTCTGCCTCAATGTTTACTGTGCCTTTGTTTTTGCTAGTGTGTGTTGTTGAA
AAAAAAAACATTCTCTGCCTGAGTTTTAATTTTTGTCCAAAGTTATTTTAATCTATACAATTAAAAGCTTTTGCCTATCACTCTGGACTG
TTGGATTGTTTTTTACATTCAGTGTTATAATCTTTTGTTATGCTGATTGGTTTTGGTGGGTACTGATGTGAATTAATAAAAACATTTCCA

>In-frame_ENST00000503676_ENST00000430580_TCGA-QH-A6CV-01A_SPOP_chr17_47688642_-_NBPF1_chr1_16890681_length(amino acids)=226AA_start in transcript=626_stop in transcript=1306
MAMSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYL
LLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNM

--------------------------------------------------------------
>In-frame_ENST00000393328_ENST00000430580_TCGA-QH-A6CV_SPOP_chr17_47688641_-_NBPF1_chr1_16890681_length(transcript)=2892nt_BP=1024nt
GTGCTGACGCCATGACGCCCCGGCTGGTGTGTGTCGGTGTGTATGTGTGTGTGTGAGTGTGCGCGCTCCGAGTGTGTGTGTATTTGTGTA
TCGGCGGTCCCGCAGGTCCCGGATGTTGCGGACAGTATGAGGCAAGCGCAGGGGGACGGGGACCAGCAGCTGTCGCCGCCGCTCTCAGAT
CGAGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGCGATCTCAGCTCACTGCCACCTTTGCCTCCTGGGTTCAAGCGATTCTTCTG
CCTCAGCCTCCCGAGTAGCTGGGATTACAGGGTGAAGAGGGAACAGAAATCTTTGCCCCCTGACTTTGGAAATCTCGTTTAACCTTCAAA
CTGGCGATGTCAAGGGTTCCAAGTCCTCCACCTCCGGCAGAAATGTCGAGTGGCCCCGTAGCTGAGAGTTGGTGCTACACACAGATCAAG
GTAGTGAAATTCTCCTACATGTGGACCATCAATAACTTTAGCTTTTGCCGGGAGGAAATGGGTGAAGTCATTAAAAGTTCTACATTTTCA
TCAGGAGCAAATGATAAACTGAAATGGTGTTTGCGAGTAAACCCCAAAGGGTTAGATGAAGAAAGCAAAGATTACCTGTCACTTTACCTG
TTACTGGTCAGCTGTCCAAAGAGTGAAGTTCGGGCAAAATTCAAATTCTCCATCCTGAATGCCAAGGGAGAAGAAACCAAAGCTATGGAG
AGTCAACGGGCATATAGGTTTGTGCAAGGCAAAGACTGGGGATTCAAGAAATTCATCCGTAGAGATTTTCTTTTGGATGAGGCCAACGGG
CTTCTCCCTGATGACAAGCTTACCCTCTTCTGCGAGGTGAGTGTTGTGCAAGATTCTGTCAACATTTCTGGCCAGAATACCATGAACATG
GTAAAGGTTCCTGAGTGCCGGCTGGCAGATGAGTTAGGAGGACTGTGGGAGAATTCCCGGTTCACAGACTGCTGCTTGTGTGTTGCCGGC
CAGGAATTCCAGGCTCACAAGGCTATCTTAGCAGGCTCAGCGGCATGCTGATGGAAGTGGAAGAGCCTGAAGTCTTGCAGGACTCACTGG
ATAGATGTTATTCGACTCCGTCAATGTACTTTGAACTACCTGACTCATTCCAGCACTACAGAAGTGTGTTTTACTCATTTGAGGAACAGC
ACATCAGCTTCGCCCTTGACGTGGACAATAGGTTTCTTACTTTGATGGGAACAAGTCTCCACCTGGTCTTCCAGATGGGAGTCATATTCC
CACAGTAAGCAGCCCTTACTAAGCCGAGAGATGTCATTCCTGCAGGCAGGACCTATAGGCACGTGAAGATTTGAATGAAACTATAGTTCC
ATTTGGAAGCCCAGACATAGGATGGGTCAGTGGGCATGGCTCTATTCCTATTCTCAGACCATGCCAGTGGCACCCTGTGCTCAGTCTGAA
GACAATGGACCCAAGTTAGGTGTGACACGTTCACATAACTGTGCAGCACATGCCGGGAGTGATCAGTCAGACATTTTAATTTGAACCACT
TATCTCTGGGTAGCTACAAAGTTCCTCAGGGATTTCATTTTGCAGTCATGTCTCTGAGCTTCTATACCTGCTCAAGGTCAGTGTCATCTT
TGTGTTTAGCTCATCCAAAGGTGTTACCCTGGTTTCAATGAACCTAACCTCATTCTTTGTATCTTCAGTGTTGAATTGTTTTAGCTGATC
CATCTTTAACACAGGAGGGATCCTTGGCTGAGGATTGTATTTCAGAACCACCAACTGCTCTTGACAATTGTTAACCCGCTAGGCTCCTTT
GGTTAGAGAAGCCACAGTCCTTCAGCCTCCAATTGGTGTCAGTACTTAGGAAGACCACAGCTAGATGGACAAACAGCATTGGGAGGCCTT
AGCCCTGCTCCTCTCGATTCCATCCTGTAGAGAACAGGAGTCAGGAGCCGCTGGCAGGAGACAGCATGTCACCCAGGACTCTGCCGGTGC
AGAATATGAACAACGCCATGTTCTTGCAGAAAACGCTTAGCCTGAGTTTCATAGGAGGTAATTACCAGACAACTGCAGAATGTAGAACAC
TGAGCAGGACAACTGACCTGTCTCCTTCACATAGTCCATATCACCACAAATCACACAACAAAAAGGAGAAGAGATATTTTGGGTTCAAAA
AAAGTAAAAAGATAATATAGCTGCATTTCTTTAGTTATTTTGAACCCCAAATATTTCCTCATCTTTTTGTTGTTGTCATTGATGGTGGTG
ACATGGACTTGTTTATAGAGGACAGGTCAGCTCTCTGGCTCAATGATCTACATTCTGAAGTTGTCTGAAAATGTCTTCATGATTAAATTC
AGCCTAAACGTTTTGCCGGGAACACTGCAGAGACAATGCTGTGAGTTTCCAACCTTAGCCCATCTGCGGGCAGAGAAGGTCTAGTTTGTC
CATCAGCATTATCATGATATCAGGACTGGTTACTTGGTTAAGGAGGGGTCTAGGAGATCTGTCCCTTTTAGAGACACCTTACTTATAATG
AAGTATTTGGGAGGGTGGTTTTCAAAATTAGAAATGTCCTGTATTCCAATGATCATCCTGTAAACATTTTATCATTTATTAATCATCCCT
GCCTGTGTCTATTATTATATTCATATCTCTACGCTGGAAACTTTCTGCCTCAATGTTTACTGTGCCTTTGTTTTTGCTAGTGTGTGTTGT
TGAAAAAAAAAACATTCTCTGCCTGAGTTTTAATTTTTGTCCAAAGTTATTTTAATCTATACAATTAAAAGCTTTTGCCTATCACTCTGG
ACTGTTGGATTGTTTTTTACATTCAGTGTTATAATCTTTTGTTATGCTGATTGGTTTTGGTGGGTACTGATGTGAATTAATAAAAACATT

>In-frame_ENST00000393328_ENST00000430580_TCGA-QH-A6CV_SPOP_chr17_47688641_-_NBPF1_chr1_16890681_length(amino acids)=226AA_start in transcript=360_stop in transcript=1040
MAMSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYL
LLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNM

--------------------------------------------------------------
>In-frame_ENST00000503676_ENST00000430580_TCGA-QH-A6CV_SPOP_chr17_47688641_-_NBPF1_chr1_16890681_length(transcript)=3158nt_BP=1290nt
ATATAGCTTAAAGCATTTAACTGGAAAGGACCTTGGAAATCCTTTTAAAGGAGGATGGGGGTGGAAATGCACAGGTTGCTTCTCTCTCTC
TCTCTCTTTTTTTTTTTTTTTGAGACGGTCACCCAGGCTGTAGTGCAGTGGCGTGATCTCGGCTCACTGTGGCCTCCACCTCCCAAGTAG
CTGGGATTACAGGCTTGCGCCATCATGCAGGGCTAATTTTTGTATTTTTAGTAGAGACGAGGTTTCATCATGTTGGCCAGGCTGGTCTGG
AACTCCTGACCTCAAGTGATCTGCCCACCTTGGCCTCCCAAAGTGCTGGGATTAAAGGCATGAGCCACCACGCCTGGCCTAGGTTGTTCC
TCTACTGTGAATCTTGAGGTTATGGTTTCCACTAGACTATAGTGCTCAACTATAGTGGCCTATTTTAAGTGGCCTTATAATTCCTAACCA
AAGTGACTTGTGAAACAGAGGACCCTGGATAAATTTAAATGTTATAAAGATGATAAAATGTACAGAGATTTCCTGTTAGACAAGACAAAT
TAGAGTTTTCCTACTGACTTAACTTGGGTGAAGAGGGAACAGAAATCTTTGCCCCCTGACTTTGGAAATCTCGTTTAACCTTCAAACTGG
CGATGTCAAGGGTTCCAAGTCCTCCACCTCCGGCAGAAATGTCGAGTGGCCCCGTAGCTGAGAGTTGGTGCTACACACAGATCAAGGTAG
TGAAATTCTCCTACATGTGGACCATCAATAACTTTAGCTTTTGCCGGGAGGAAATGGGTGAAGTCATTAAAAGTTCTACATTTTCATCAG
GAGCAAATGATAAACTGAAATGGTGTTTGCGAGTAAACCCCAAAGGGTTAGATGAAGAAAGCAAAGATTACCTGTCACTTTACCTGTTAC
TGGTCAGCTGTCCAAAGAGTGAAGTTCGGGCAAAATTCAAATTCTCCATCCTGAATGCCAAGGGAGAAGAAACCAAAGCTATGGAGAGTC
AACGGGCATATAGGTTTGTGCAAGGCAAAGACTGGGGATTCAAGAAATTCATCCGTAGAGATTTTCTTTTGGATGAGGCCAACGGGCTTC
TCCCTGATGACAAGCTTACCCTCTTCTGCGAGGTGAGTGTTGTGCAAGATTCTGTCAACATTTCTGGCCAGAATACCATGAACATGGTAA
AGGTTCCTGAGTGCCGGCTGGCAGATGAGTTAGGAGGACTGTGGGAGAATTCCCGGTTCACAGACTGCTGCTTGTGTGTTGCCGGCCAGG
AATTCCAGGCTCACAAGGCTATCTTAGCAGGCTCAGCGGCATGCTGATGGAAGTGGAAGAGCCTGAAGTCTTGCAGGACTCACTGGATAG
ATGTTATTCGACTCCGTCAATGTACTTTGAACTACCTGACTCATTCCAGCACTACAGAAGTGTGTTTTACTCATTTGAGGAACAGCACAT
CAGCTTCGCCCTTGACGTGGACAATAGGTTTCTTACTTTGATGGGAACAAGTCTCCACCTGGTCTTCCAGATGGGAGTCATATTCCCACA
GTAAGCAGCCCTTACTAAGCCGAGAGATGTCATTCCTGCAGGCAGGACCTATAGGCACGTGAAGATTTGAATGAAACTATAGTTCCATTT
GGAAGCCCAGACATAGGATGGGTCAGTGGGCATGGCTCTATTCCTATTCTCAGACCATGCCAGTGGCACCCTGTGCTCAGTCTGAAGACA
ATGGACCCAAGTTAGGTGTGACACGTTCACATAACTGTGCAGCACATGCCGGGAGTGATCAGTCAGACATTTTAATTTGAACCACTTATC
TCTGGGTAGCTACAAAGTTCCTCAGGGATTTCATTTTGCAGTCATGTCTCTGAGCTTCTATACCTGCTCAAGGTCAGTGTCATCTTTGTG
TTTAGCTCATCCAAAGGTGTTACCCTGGTTTCAATGAACCTAACCTCATTCTTTGTATCTTCAGTGTTGAATTGTTTTAGCTGATCCATC
TTTAACACAGGAGGGATCCTTGGCTGAGGATTGTATTTCAGAACCACCAACTGCTCTTGACAATTGTTAACCCGCTAGGCTCCTTTGGTT
AGAGAAGCCACAGTCCTTCAGCCTCCAATTGGTGTCAGTACTTAGGAAGACCACAGCTAGATGGACAAACAGCATTGGGAGGCCTTAGCC
CTGCTCCTCTCGATTCCATCCTGTAGAGAACAGGAGTCAGGAGCCGCTGGCAGGAGACAGCATGTCACCCAGGACTCTGCCGGTGCAGAA
TATGAACAACGCCATGTTCTTGCAGAAAACGCTTAGCCTGAGTTTCATAGGAGGTAATTACCAGACAACTGCAGAATGTAGAACACTGAG
CAGGACAACTGACCTGTCTCCTTCACATAGTCCATATCACCACAAATCACACAACAAAAAGGAGAAGAGATATTTTGGGTTCAAAAAAAG
TAAAAAGATAATATAGCTGCATTTCTTTAGTTATTTTGAACCCCAAATATTTCCTCATCTTTTTGTTGTTGTCATTGATGGTGGTGACAT
GGACTTGTTTATAGAGGACAGGTCAGCTCTCTGGCTCAATGATCTACATTCTGAAGTTGTCTGAAAATGTCTTCATGATTAAATTCAGCC
TAAACGTTTTGCCGGGAACACTGCAGAGACAATGCTGTGAGTTTCCAACCTTAGCCCATCTGCGGGCAGAGAAGGTCTAGTTTGTCCATC
AGCATTATCATGATATCAGGACTGGTTACTTGGTTAAGGAGGGGTCTAGGAGATCTGTCCCTTTTAGAGACACCTTACTTATAATGAAGT
ATTTGGGAGGGTGGTTTTCAAAATTAGAAATGTCCTGTATTCCAATGATCATCCTGTAAACATTTTATCATTTATTAATCATCCCTGCCT
GTGTCTATTATTATATTCATATCTCTACGCTGGAAACTTTCTGCCTCAATGTTTACTGTGCCTTTGTTTTTGCTAGTGTGTGTTGTTGAA
AAAAAAAACATTCTCTGCCTGAGTTTTAATTTTTGTCCAAAGTTATTTTAATCTATACAATTAAAAGCTTTTGCCTATCACTCTGGACTG
TTGGATTGTTTTTTACATTCAGTGTTATAATCTTTTGTTATGCTGATTGGTTTTGGTGGGTACTGATGTGAATTAATAAAAACATTTCCA

>In-frame_ENST00000503676_ENST00000430580_TCGA-QH-A6CV_SPOP_chr17_47688641_-_NBPF1_chr1_16890681_length(amino acids)=226AA_start in transcript=626_stop in transcript=1306
MAMSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYL
LLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNM

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SPOP-NBPF1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SPOP-NBPF1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SPOP-NBPF1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneSPOPC0033578Prostatic Neoplasms3CTD_human
HgeneSPOPC0376358Malignant neoplasm of prostate3CTD_human;GENOMICS_ENGLAND
HgeneSPOPC0014170Endometrial Neoplasms1CTD_human
HgeneSPOPC0476089Endometrial Carcinoma1CGI;CTD_human
HgeneSPOPC1176475Ductal Carcinoma1CTD_human