FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:SS18-SSX2B (FusionGDB2 ID:86074)

Fusion Gene Summary for SS18-SSX2B

check button Fusion gene summary
Fusion gene informationFusion gene name: SS18-SSX2B
Fusion gene ID: 86074
HgeneTgene
Gene symbol

SS18

SSX2B

Gene ID

6760

727837

Gene nameSS18 subunit of BAF chromatin remodeling complexSSX family member 2B
SynonymsSSXT|SYTCT5.2|CT5.2b|HOM-MEL-40|SSX
Cytomap

18q11.2

Xp11.22

Type of geneprotein-codingprotein-coding
Descriptionprotein SSXTSS18, nBAF chromatin remodeling complex subunitsynovial sarcoma translocated to X chromosome proteinsynovial sarcoma translocation, chromosome 18synovial sarcoma, translocated to X chromosomeprotein SSX2cancer/testis antigen 5.2cancer/testis antigen family 5, member 2bsynovial sarcoma, X breakpoint 2Btumor antigen HOM-MEL-40
Modification date2020032920200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000415083, ENST00000542420, 
ENST00000542743, ENST00000539849, 
ENST00000269137, ENST00000545952, 
ENST00000585241, 		ENST00000375515, 
ENST00000276049, ENST00000288839, 
Fusion gene scores* DoF score24 X 33 X 8=63362 X 3 X 2=12
# samples 383
** MAII scorelog2(38/6336*10)=-4.05950101174866
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/12*10)=1.32192809488736
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: SS18 [Title/Abstract] AND SSX2B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSS18(23612363)-SSX2B(52786929), # samples:2
Anticipated loss of major functional domain due to fusion event.SS18-SSX2B seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSS18

GO:0045944

positive regulation of transcription by RNA polymerase II

15919756


check buttonFusion gene breakpoints across SS18 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across SSX2B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/AAB012575SS18chr18

23612363

-SSX2BchrX

52786929

+
ChiTaRS5.0N/AAB300357SS18chr18

23612363

-SSX2BchrX

52786929

+
ChiTaRS5.0N/AAY138492SS18chr18

23608220

-SSX2BchrX

52786697

+


Top

Fusion Gene ORF analysis for SS18-SSX2B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000415083ENST00000375515SS18chr18

23612363

-SSX2BchrX

52786929

+
In-frameENST00000415083ENST00000276049SS18chr18

23612363

-SSX2BchrX

52786929

+
5CDS-3UTRENST00000415083ENST00000288839SS18chr18

23612363

-SSX2BchrX

52786929

+
Frame-shiftENST00000542420ENST00000375515SS18chr18

23612363

-SSX2BchrX

52786929

+
Frame-shiftENST00000542420ENST00000276049SS18chr18

23612363

-SSX2BchrX

52786929

+
5CDS-3UTRENST00000542420ENST00000288839SS18chr18

23612363

-SSX2BchrX

52786929

+
Frame-shiftENST00000542743ENST00000375515SS18chr18

23612363

-SSX2BchrX

52786929

+
Frame-shiftENST00000542743ENST00000276049SS18chr18

23612363

-SSX2BchrX

52786929

+
5CDS-3UTRENST00000542743ENST00000288839SS18chr18

23612363

-SSX2BchrX

52786929

+
Frame-shiftENST00000539849ENST00000375515SS18chr18

23612363

-SSX2BchrX

52786929

+
Frame-shiftENST00000539849ENST00000276049SS18chr18

23612363

-SSX2BchrX

52786929

+
5CDS-3UTRENST00000539849ENST00000288839SS18chr18

23612363

-SSX2BchrX

52786929

+
In-frameENST00000269137ENST00000375515SS18chr18

23612363

-SSX2BchrX

52786929

+
In-frameENST00000269137ENST00000276049SS18chr18

23612363

-SSX2BchrX

52786929

+
5CDS-3UTRENST00000269137ENST00000288839SS18chr18

23612363

-SSX2BchrX

52786929

+
In-frameENST00000545952ENST00000375515SS18chr18

23612363

-SSX2BchrX

52786929

+
In-frameENST00000545952ENST00000276049SS18chr18

23612363

-SSX2BchrX

52786929

+
5CDS-3UTRENST00000545952ENST00000288839SS18chr18

23612363

-SSX2BchrX

52786929

+
intron-3CDSENST00000585241ENST00000375515SS18chr18

23612363

-SSX2BchrX

52786929

+
intron-3CDSENST00000585241ENST00000276049SS18chr18

23612363

-SSX2BchrX

52786929

+
intron-3UTRENST00000585241ENST00000288839SS18chr18

23612363

-SSX2BchrX

52786929

+
intron-intronENST00000415083ENST00000375515SS18chr18

23608220

-SSX2BchrX

52786697

+
intron-intronENST00000415083ENST00000276049SS18chr18

23608220

-SSX2BchrX

52786697

+
intron-intronENST00000415083ENST00000288839SS18chr18

23608220

-SSX2BchrX

52786697

+
intron-intronENST00000542420ENST00000375515SS18chr18

23608220

-SSX2BchrX

52786697

+
intron-intronENST00000542420ENST00000276049SS18chr18

23608220

-SSX2BchrX

52786697

+
intron-intronENST00000542420ENST00000288839SS18chr18

23608220

-SSX2BchrX

52786697

+
intron-intronENST00000542743ENST00000375515SS18chr18

23608220

-SSX2BchrX

52786697

+
intron-intronENST00000542743ENST00000276049SS18chr18

23608220

-SSX2BchrX

52786697

+
intron-intronENST00000542743ENST00000288839SS18chr18

23608220

-SSX2BchrX

52786697

+
intron-intronENST00000539849ENST00000375515SS18chr18

23608220

-SSX2BchrX

52786697

+
intron-intronENST00000539849ENST00000276049SS18chr18

23608220

-SSX2BchrX

52786697

+
intron-intronENST00000539849ENST00000288839SS18chr18

23608220

-SSX2BchrX

52786697

+
intron-intronENST00000269137ENST00000375515SS18chr18

23608220

-SSX2BchrX

52786697

+
intron-intronENST00000269137ENST00000276049SS18chr18

23608220

-SSX2BchrX

52786697

+
intron-intronENST00000269137ENST00000288839SS18chr18

23608220

-SSX2BchrX

52786697

+
intron-intronENST00000545952ENST00000375515SS18chr18

23608220

-SSX2BchrX

52786697

+
intron-intronENST00000545952ENST00000276049SS18chr18

23608220

-SSX2BchrX

52786697

+
intron-intronENST00000545952ENST00000288839SS18chr18

23608220

-SSX2BchrX

52786697

+
intron-intronENST00000585241ENST00000375515SS18chr18

23608220

-SSX2BchrX

52786697

+
intron-intronENST00000585241ENST00000276049SS18chr18

23608220

-SSX2BchrX

52786697

+
intron-intronENST00000585241ENST00000288839SS18chr18

23608220

-SSX2BchrX

52786697

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000415083SS18chr1823612363-ENST00000375515SSX2BchrX52786929+21541286561522488
ENST00000415083SS18chr1823612363-ENST00000276049SSX2BchrX52786929+23001286561627523
ENST00000269137SS18chr1823612363-ENST00000375515SSX2BchrX52786929+233714691611705514
ENST00000269137SS18chr1823612363-ENST00000276049SSX2BchrX52786929+248314691611810549
ENST00000545952SS18chr1823612363-ENST00000375515SSX2BchrX52786929+215212843031520405
ENST00000545952SS18chr1823612363-ENST00000276049SSX2BchrX52786929+229812843031625440

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000415083ENST00000375515SS18chr1823612363-SSX2BchrX52786929+0.0036182370.99638176
ENST00000415083ENST00000276049SS18chr1823612363-SSX2BchrX52786929+0.0070200010.99298006
ENST00000269137ENST00000375515SS18chr1823612363-SSX2BchrX52786929+0.0037440850.9962559
ENST00000269137ENST00000276049SS18chr1823612363-SSX2BchrX52786929+0.0068135980.99318635
ENST00000545952ENST00000375515SS18chr1823612363-SSX2BchrX52786929+0.0015837850.9984162
ENST00000545952ENST00000276049SS18chr1823612363-SSX2BchrX52786929+0.0031391050.99686086

Top

Fusion Genomic Features for SS18-SSX2B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SS18chr1823612362-SSX2BchrX52786930+2.61E-060.9999974
SS18chr1823612362-SSX2BchrX52786930+2.61E-060.9999974

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for SS18-SSX2B


check button Go to

FGviewer for the breakpoints of chr18:23612363-chrX:52786929

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSS18chr18:23612363chrX:52786929ENST00000269137-91095_99379.0388.0Compositional biasNote=Poly-Pro
HgeneSS18chr18:23612363chrX:52786929ENST00000415083-101195_99410.0419.0Compositional biasNote=Poly-Pro
HgeneSS18chr18:23612363chrX:52786929ENST00000269137-910374_377379.0388.0MotifSH2-binding
HgeneSS18chr18:23612363chrX:52786929ENST00000269137-91050_53379.0388.0MotifSH2-binding
HgeneSS18chr18:23612363chrX:52786929ENST00000415083-1011374_377410.0419.0MotifSH2-binding
HgeneSS18chr18:23612363chrX:52786929ENST00000415083-1011392_401410.0419.0MotifSH3-binding
HgeneSS18chr18:23612363chrX:52786929ENST00000415083-101150_53410.0419.0MotifSH2-binding
HgeneSS18chr18:23612363chrX:52786929ENST00000269137-9102_186379.0388.0RegionNote=Transcriptional activation
HgeneSS18chr18:23612363chrX:52786929ENST00000269137-910344_369379.0388.0RegionNote=2 X 13 AA imperfect tandem repeats
HgeneSS18chr18:23612363chrX:52786929ENST00000415083-10112_186410.0419.0RegionNote=Transcriptional activation
HgeneSS18chr18:23612363chrX:52786929ENST00000415083-1011344_369410.0419.0RegionNote=2 X 13 AA imperfect tandem repeats
HgeneSS18chr18:23612363chrX:52786929ENST00000269137-910344_356379.0388.0RepeatNote=1
HgeneSS18chr18:23612363chrX:52786929ENST00000269137-910357_369379.0388.0RepeatNote=2
HgeneSS18chr18:23612363chrX:52786929ENST00000415083-1011344_356410.0419.0RepeatNote=1
HgeneSS18chr18:23612363chrX:52786929ENST00000415083-1011357_369410.0419.0RepeatNote=2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSS18chr18:23612363chrX:52786929ENST00000269137-910175_418379.0388.0Compositional biasNote=Gln-rich
HgeneSS18chr18:23612363chrX:52786929ENST00000415083-1011175_418410.0419.0Compositional biasNote=Gln-rich
HgeneSS18chr18:23612363chrX:52786929ENST00000269137-910392_401379.0388.0MotifSH3-binding
HgeneSS18chr18:23612363chrX:52786929ENST00000269137-910413_416379.0388.0MotifSH2-binding
HgeneSS18chr18:23612363chrX:52786929ENST00000415083-1011413_416410.0419.0MotifSH2-binding
TgeneSSX2Bchr18:23612363chrX:52786929ENST000002760494920_83110.0416.3333333333333DomainKRAB-related
TgeneSSX2Bchr18:23612363chrX:52786929ENST000003755154820_83110.0372.0DomainKRAB-related


Top

Fusion Gene Sequence for SS18-SSX2B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000415083_ENST00000375515_AB012575_SS18_chr18_23612363_-_SSX2B_chrX_52786929_length(transcript)=2154nt_BP=1286nt
AGTTTGCCGTTCACCCGGAGCGCTCGGGACTTGCCGATAGTGGTGACGGCGGCAACATGTCTGTGGCTTTCGCGGCCCCGAGGCAGCGAG
GCAAGGGGGAGATCACTCCCGCTGCGATTCAGAAGATGTTGGATGACAATAACCATCTTATTCAGTGTATAATGGACTCTCAGAATAAAG
GAAAGACCTCAGAGTGTTCTCAGTATCAGCAGATGTTGCACACAAACTTGGTATACCTTGCTACAATAGCAGATTCTAATCAAAATATGC
AGTCTCTTTTACCAGCACCACCCACACAGAATATGCCTATGGGTCCTGGAGGGATGAATCAGAGCGGCCCTCCCCCACCTCCACGCTCTC
ACAACATGCCTTCAGATGGAATGGTAGGTGGGGGTCCTCCTGCACCGCACATGCAGAACCAGATGAACGGCCAGATGCCTGGGCCTAACC
ATATGCCTATGCAGGGACCTGGACCCAATCAACTCAATATGACAAACAGTTCCATGAATATGCCTTCAAGTAGCCATGGATCCATGGGAG
GTTACAACCATTCTGTGCCATCATCACAGAGCATGCCAGTACAGAATCAGATGACAATGAGTCAGGGACAACCAATGGGAAACTATGGTC
CCAGACCAAATATGAGTATGCAGCCAAACCAAGGTCCAATGATGCATCAGCAGCCTCCTTCTCAGCAATACAATATGCCACAGGGAGGCG
GACAGCATTACCAAGGACAGCAGCCACCTATGGGAATGATGGGTCAAGTTAACCAAGGCAATCATATGATGGGTCAGAGACAGATTCCTC
CCTATAGACCTCCTCAACAGGGCCCACCACAGCAGTACTCAGGCCAGGAAGACTATTACGGGGACCAATACAGTCATGGTGGACAAGGTC
CTCCAGAAGGCATGAACCAGCAATATTACCCTGATGGTCATAATGATTACGGTTATCAGCAACCGTCGTATCCTGAACAAGGCTACGATA
GGCCTTATGAGGATTCCTCACAACATTACTACGAAGGAGGAAATTCACAGTATGGCCAACAGCAAGATGCATACCAGGGACCACCTCCAC
AACAGGGATATCCACCCCAGCAGCAGCAGTACCCAGGGCAGCAAGGTTACCCAGGACAGCAGCAGGGCTACGGTCCTTCACAGGGTGGTC
CAGGTCCTCAGTATCCTAACTACCCACAGGGACAAGGTCAGCAGTATGGAGGATATAGACCAACACAGCCTGGACCACCACAGCCACCCC
AGCAGAGGCCTTATGGATATGACCAGATCATGCCCAAGAAGCCAGCAGAGGAAGGAAATGATTCGGAGGAAGTGCCAGAAGCATCTGGCC
CACAAAATGATGGGAAAGAGCTGTGCCCCCCGGGAAAACCAACTACCTCTGAGAAGATTCACGAGAGATCTGGACCCAAAAGGGGGGAAC
ATGCCTGGACCCACAGACTGCGTGAGAGAAAACAGCTGGTGATTTATGAAGAGATCAGCGACCCTGAGGAAGATGACGAGTAACTCCCCT
CAGGGATACGACACATGCCCATGATGAGAAGCAGAACGTGGTGACCTTTCACGAACATGGGCATGGCTGCGGACCCCTCGTCATCAGGTG
CATAGCAAGTGAAAGCAAGTGTTCACAACAGTGAAAAGTTGAGCGTCATTTTTCTTAGTGTGCCAAGAGTTCGATGTTAGCGTTTACGTT
GTATTTTCTTACACTGTGTCATTCTGTTAGATACTAACATTTTCATTGATGAGCAAGACATACTTAATGCATATTTTGGTTTGTGTATCC
ATGCACCTACCTTAGAAAACAAGTATTGTCGGTTACCTCTGCATGGAACAGCATTACCCTCCTCTCTCCCCAGATGTGACTACTGAGGGC
AGTTCTGAGTGTTTAATTTCAGATTTTTTCCTCTGCATTTACACACACACGCACACAAACCACACCACACACACACACACACACACACAC
ACACACACACACACACACACACCAAGTACCAGTATAAGCATCTGCCATCTGCTTTTCCCATTGCCATGCGTCCTGGTCAAGCTCCCCTCA

>In-frame_ENST00000415083_ENST00000375515_AB012575_SS18_chr18_23612363_-_SSX2B_chrX_52786929_length(amino acids)=488AA_start in transcript=56_stop in transcript=1522
MSVAFAAPRQRGKGEITPAAIQKMLDDNNHLIQCIMDSQNKGKTSECSQYQQMLHTNLVYLATIADSNQNMQSLLPAPPTQNMPMGPGGM
NQSGPPPPPRSHNMPSDGMVGGGPPAPHMQNQMNGQMPGPNHMPMQGPGPNQLNMTNSSMNMPSSSHGSMGGYNHSVPSSQSMPVQNQMT
MSQGQPMGNYGPRPNMSMQPNQGPMMHQQPPSQQYNMPQGGGQHYQGQQPPMGMMGQVNQGNHMMGQRQIPPYRPPQQGPPQQYSGQEDY
YGDQYSHGGQGPPEGMNQQYYPDGHNDYGYQQPSYPEQGYDRPYEDSSQHYYEGGNSQYGQQQDAYQGPPPQQGYPPQQQQYPGQQGYPG
QQQGYGPSQGGPGPQYPNYPQGQGQQYGGYRPTQPGPPQPPQQRPYGYDQIMPKKPAEEGNDSEEVPEASGPQNDGKELCPPGKPTTSEK

--------------------------------------------------------------
>In-frame_ENST00000415083_ENST00000276049_AB012575_SS18_chr18_23612363_-_SSX2B_chrX_52786929_length(transcript)=2300nt_BP=1286nt
AGTTTGCCGTTCACCCGGAGCGCTCGGGACTTGCCGATAGTGGTGACGGCGGCAACATGTCTGTGGCTTTCGCGGCCCCGAGGCAGCGAG
GCAAGGGGGAGATCACTCCCGCTGCGATTCAGAAGATGTTGGATGACAATAACCATCTTATTCAGTGTATAATGGACTCTCAGAATAAAG
GAAAGACCTCAGAGTGTTCTCAGTATCAGCAGATGTTGCACACAAACTTGGTATACCTTGCTACAATAGCAGATTCTAATCAAAATATGC
AGTCTCTTTTACCAGCACCACCCACACAGAATATGCCTATGGGTCCTGGAGGGATGAATCAGAGCGGCCCTCCCCCACCTCCACGCTCTC
ACAACATGCCTTCAGATGGAATGGTAGGTGGGGGTCCTCCTGCACCGCACATGCAGAACCAGATGAACGGCCAGATGCCTGGGCCTAACC
ATATGCCTATGCAGGGACCTGGACCCAATCAACTCAATATGACAAACAGTTCCATGAATATGCCTTCAAGTAGCCATGGATCCATGGGAG
GTTACAACCATTCTGTGCCATCATCACAGAGCATGCCAGTACAGAATCAGATGACAATGAGTCAGGGACAACCAATGGGAAACTATGGTC
CCAGACCAAATATGAGTATGCAGCCAAACCAAGGTCCAATGATGCATCAGCAGCCTCCTTCTCAGCAATACAATATGCCACAGGGAGGCG
GACAGCATTACCAAGGACAGCAGCCACCTATGGGAATGATGGGTCAAGTTAACCAAGGCAATCATATGATGGGTCAGAGACAGATTCCTC
CCTATAGACCTCCTCAACAGGGCCCACCACAGCAGTACTCAGGCCAGGAAGACTATTACGGGGACCAATACAGTCATGGTGGACAAGGTC
CTCCAGAAGGCATGAACCAGCAATATTACCCTGATGGTCATAATGATTACGGTTATCAGCAACCGTCGTATCCTGAACAAGGCTACGATA
GGCCTTATGAGGATTCCTCACAACATTACTACGAAGGAGGAAATTCACAGTATGGCCAACAGCAAGATGCATACCAGGGACCACCTCCAC
AACAGGGATATCCACCCCAGCAGCAGCAGTACCCAGGGCAGCAAGGTTACCCAGGACAGCAGCAGGGCTACGGTCCTTCACAGGGTGGTC
CAGGTCCTCAGTATCCTAACTACCCACAGGGACAAGGTCAGCAGTATGGAGGATATAGACCAACACAGCCTGGACCACCACAGCCACCCC
AGCAGAGGCCTTATGGATATGACCAGATCATGCCCAAGAAGCCAGCAGAGGAAGGAAATGATTCGGAGGAAGTGCCAGAAGCATCTGGCC
CACAAAATGATGGGAAAGAGCTGTGCCCCCCGGGAAAACCAACTACCTCTGAGAAGATTCACGAGAGATCTGGAAATAGGGAGGCCCAAG
AAAAGGAAGAGAGACGCGGAACAGCTCATCGGTGGAGCAGTCAGAACACACACAACATTGGTCGATTCAGTTTGTCAACTTCTATGGGTG
CAGTTCATGGTACCCCCAAAACAATTACACACAACAGGGACCCAAAAGGGGGGAACATGCCTGGACCCACAGACTGCGTGAGAGAAAACA
GCTGGTGATTTATGAAGAGATCAGCGACCCTGAGGAAGATGACGAGTAACTCCCCTCAGGGATACGACACATGCCCATGATGAGAAGCAG
AACGTGGTGACCTTTCACGAACATGGGCATGGCTGCGGACCCCTCGTCATCAGGTGCATAGCAAGTGAAAGCAAGTGTTCACAACAGTGA
AAAGTTGAGCGTCATTTTTCTTAGTGTGCCAAGAGTTCGATGTTAGCGTTTACGTTGTATTTTCTTACACTGTGTCATTCTGTTAGATAC
TAACATTTTCATTGATGAGCAAGACATACTTAATGCATATTTTGGTTTGTGTATCCATGCACCTACCTTAGAAAACAAGTATTGTCGGTT
ACCTCTGCATGGAACAGCATTACCCTCCTCTCTCCCCAGATGTGACTACTGAGGGCAGTTCTGAGTGTTTAATTTCAGATTTTTTCCTCT
GCATTTACACACACACGCACACAAACCACACCACACACACACACACACACACACACACACACACACACACACACACACCAAGTACCAGTA
TAAGCATCTGCCATCTGCTTTTCCCATTGCCATGCGTCCTGGTCAAGCTCCCCTCACTCTGTTTCCTGGTCAGCATGTACTCCCCTCATC

>In-frame_ENST00000415083_ENST00000276049_AB012575_SS18_chr18_23612363_-_SSX2B_chrX_52786929_length(amino acids)=523AA_start in transcript=56_stop in transcript=1627
MSVAFAAPRQRGKGEITPAAIQKMLDDNNHLIQCIMDSQNKGKTSECSQYQQMLHTNLVYLATIADSNQNMQSLLPAPPTQNMPMGPGGM
NQSGPPPPPRSHNMPSDGMVGGGPPAPHMQNQMNGQMPGPNHMPMQGPGPNQLNMTNSSMNMPSSSHGSMGGYNHSVPSSQSMPVQNQMT
MSQGQPMGNYGPRPNMSMQPNQGPMMHQQPPSQQYNMPQGGGQHYQGQQPPMGMMGQVNQGNHMMGQRQIPPYRPPQQGPPQQYSGQEDY
YGDQYSHGGQGPPEGMNQQYYPDGHNDYGYQQPSYPEQGYDRPYEDSSQHYYEGGNSQYGQQQDAYQGPPPQQGYPPQQQQYPGQQGYPG
QQQGYGPSQGGPGPQYPNYPQGQGQQYGGYRPTQPGPPQPPQQRPYGYDQIMPKKPAEEGNDSEEVPEASGPQNDGKELCPPGKPTTSEK

--------------------------------------------------------------
>In-frame_ENST00000269137_ENST00000375515_AB012575_SS18_chr18_23612363_-_SSX2B_chrX_52786929_length(transcript)=2337nt_BP=1469nt
TTTCCTGAATCGCTGAAGCGGAGGGAGGACTAGGGCGCGACTCTACCATTAGCGCAAAGGGCCAGGGGGTGCCCATAAGGAGAGCTCGGG
GGATGCAGGGACGGTCAAGAAAGTTCGGCCAGGGCTAGGGGTCCCCCAGAGTGCGCAGAAGCGAGACATCCCTGGCCAGAGTGCCTCCTT
CAGGCCTGCCCCGCCGCCCGTCCGCTTGGCCCCGGAGCATCCCCCCTCCCCGCATTCCCGAGGTGGTTCAGCCCGAGAGGCCGGCGTCTC
TCCCCCAGTTTGCCGTTCACCCGGAGCGCTCGGGACTTGCCGATAGTGGTGACGGCGGCAACATGTCTGTGGCTTTCGCGGCCCCGAGGC
AGCGAGGCAAGGGGGAGATCACTCCCGCTGCGATTCAGAAGATGTTGGATGACAATAACCATCTTATTCAGTGTATAATGGACTCTCAGA
ATAAAGGAAAGACCTCAGAGTGTTCTCAGTATCAGCAGATGTTGCACACAAACTTGGTATACCTTGCTACAATAGCAGATTCTAATCAAA
ATATGCAGTCTCTTTTACCAGCACCACCCACACAGAATATGCCTATGGGTCCTGGAGGGATGAATCAGAGCGGCCCTCCCCCACCTCCAC
GCTCTCACAACATGCCTTCAGATGGAATGGTAGGTGGGGGTCCTCCTGCACCGCACATGCAGAACCAGATGAACGGCCAGATGCCTGGGC
CTAACCATATGCCTATGCAGGGACCTGGACCCAATCAACTCAATATGACAAACAGTTCCATGAATATGCCTTCAAGTAGCCATGGATCCA
TGGGAGGTTACAACCATTCTGTGCCATCATCACAGAGCATGCCAGTACAGAATCAGATGACAATGAGTCAGGGACAACCAATGGGAAACT
ATGGTCCCAGACCAAATATGAGTATGCAGCCAAACCAAGGTCCAATGATGCATCAGCAGCCTCCTTCTCAGCAATACAATATGCCACAGG
GAGGCGGACAGCATTACCAAGGACAGCAGCCACCTATGGGAATGATGGGTCAAGTTAACCAAGGCAATCATATGATGGGTCAGAGACAGA
TTCCTCCCTATAGACCTCCTCAACAGGGCCCACCACAGCAGTACTCAGGCCAGGAAGACTATTACGGGGACCAATACAGTCATGGTGGAC
AAGGTCCTCCAGAAGGCATGAACCAGCAATATTACCCTGATGGAAATTCACAGTATGGCCAACAGCAAGATGCATACCAGGGACCACCTC
CACAACAGGGATATCCACCCCAGCAGCAGCAGTACCCAGGGCAGCAAGGTTACCCAGGACAGCAGCAGGGCTACGGTCCTTCACAGGGTG
GTCCAGGTCCTCAGTATCCTAACTACCCACAGGGACAAGGTCAGCAGTATGGAGGATATAGACCAACACAGCCTGGACCACCACAGCCAC
CCCAGCAGAGGCCTTATGGATATGACCAGATCATGCCCAAGAAGCCAGCAGAGGAAGGAAATGATTCGGAGGAAGTGCCAGAAGCATCTG
GCCCACAAAATGATGGGAAAGAGCTGTGCCCCCCGGGAAAACCAACTACCTCTGAGAAGATTCACGAGAGATCTGGACCCAAAAGGGGGG
AACATGCCTGGACCCACAGACTGCGTGAGAGAAAACAGCTGGTGATTTATGAAGAGATCAGCGACCCTGAGGAAGATGACGAGTAACTCC
CCTCAGGGATACGACACATGCCCATGATGAGAAGCAGAACGTGGTGACCTTTCACGAACATGGGCATGGCTGCGGACCCCTCGTCATCAG
GTGCATAGCAAGTGAAAGCAAGTGTTCACAACAGTGAAAAGTTGAGCGTCATTTTTCTTAGTGTGCCAAGAGTTCGATGTTAGCGTTTAC
GTTGTATTTTCTTACACTGTGTCATTCTGTTAGATACTAACATTTTCATTGATGAGCAAGACATACTTAATGCATATTTTGGTTTGTGTA
TCCATGCACCTACCTTAGAAAACAAGTATTGTCGGTTACCTCTGCATGGAACAGCATTACCCTCCTCTCTCCCCAGATGTGACTACTGAG
GGCAGTTCTGAGTGTTTAATTTCAGATTTTTTCCTCTGCATTTACACACACACGCACACAAACCACACCACACACACACACACACACACA
CACACACACACACACACACACACACCAAGTACCAGTATAAGCATCTGCCATCTGCTTTTCCCATTGCCATGCGTCCTGGTCAAGCTCCCC

>In-frame_ENST00000269137_ENST00000375515_AB012575_SS18_chr18_23612363_-_SSX2B_chrX_52786929_length(amino acids)=514AA_start in transcript=161_stop in transcript=1705
MARVPPSGLPRRPSAWPRSIPPPRIPEVVQPERPASLPQFAVHPERSGLADSGDGGNMSVAFAAPRQRGKGEITPAAIQKMLDDNNHLIQ
CIMDSQNKGKTSECSQYQQMLHTNLVYLATIADSNQNMQSLLPAPPTQNMPMGPGGMNQSGPPPPPRSHNMPSDGMVGGGPPAPHMQNQM
NGQMPGPNHMPMQGPGPNQLNMTNSSMNMPSSSHGSMGGYNHSVPSSQSMPVQNQMTMSQGQPMGNYGPRPNMSMQPNQGPMMHQQPPSQ
QYNMPQGGGQHYQGQQPPMGMMGQVNQGNHMMGQRQIPPYRPPQQGPPQQYSGQEDYYGDQYSHGGQGPPEGMNQQYYPDGNSQYGQQQD
AYQGPPPQQGYPPQQQQYPGQQGYPGQQQGYGPSQGGPGPQYPNYPQGQGQQYGGYRPTQPGPPQPPQQRPYGYDQIMPKKPAEEGNDSE

--------------------------------------------------------------
>In-frame_ENST00000269137_ENST00000276049_AB012575_SS18_chr18_23612363_-_SSX2B_chrX_52786929_length(transcript)=2483nt_BP=1469nt
TTTCCTGAATCGCTGAAGCGGAGGGAGGACTAGGGCGCGACTCTACCATTAGCGCAAAGGGCCAGGGGGTGCCCATAAGGAGAGCTCGGG
GGATGCAGGGACGGTCAAGAAAGTTCGGCCAGGGCTAGGGGTCCCCCAGAGTGCGCAGAAGCGAGACATCCCTGGCCAGAGTGCCTCCTT
CAGGCCTGCCCCGCCGCCCGTCCGCTTGGCCCCGGAGCATCCCCCCTCCCCGCATTCCCGAGGTGGTTCAGCCCGAGAGGCCGGCGTCTC
TCCCCCAGTTTGCCGTTCACCCGGAGCGCTCGGGACTTGCCGATAGTGGTGACGGCGGCAACATGTCTGTGGCTTTCGCGGCCCCGAGGC
AGCGAGGCAAGGGGGAGATCACTCCCGCTGCGATTCAGAAGATGTTGGATGACAATAACCATCTTATTCAGTGTATAATGGACTCTCAGA
ATAAAGGAAAGACCTCAGAGTGTTCTCAGTATCAGCAGATGTTGCACACAAACTTGGTATACCTTGCTACAATAGCAGATTCTAATCAAA
ATATGCAGTCTCTTTTACCAGCACCACCCACACAGAATATGCCTATGGGTCCTGGAGGGATGAATCAGAGCGGCCCTCCCCCACCTCCAC
GCTCTCACAACATGCCTTCAGATGGAATGGTAGGTGGGGGTCCTCCTGCACCGCACATGCAGAACCAGATGAACGGCCAGATGCCTGGGC
CTAACCATATGCCTATGCAGGGACCTGGACCCAATCAACTCAATATGACAAACAGTTCCATGAATATGCCTTCAAGTAGCCATGGATCCA
TGGGAGGTTACAACCATTCTGTGCCATCATCACAGAGCATGCCAGTACAGAATCAGATGACAATGAGTCAGGGACAACCAATGGGAAACT
ATGGTCCCAGACCAAATATGAGTATGCAGCCAAACCAAGGTCCAATGATGCATCAGCAGCCTCCTTCTCAGCAATACAATATGCCACAGG
GAGGCGGACAGCATTACCAAGGACAGCAGCCACCTATGGGAATGATGGGTCAAGTTAACCAAGGCAATCATATGATGGGTCAGAGACAGA
TTCCTCCCTATAGACCTCCTCAACAGGGCCCACCACAGCAGTACTCAGGCCAGGAAGACTATTACGGGGACCAATACAGTCATGGTGGAC
AAGGTCCTCCAGAAGGCATGAACCAGCAATATTACCCTGATGGAAATTCACAGTATGGCCAACAGCAAGATGCATACCAGGGACCACCTC
CACAACAGGGATATCCACCCCAGCAGCAGCAGTACCCAGGGCAGCAAGGTTACCCAGGACAGCAGCAGGGCTACGGTCCTTCACAGGGTG
GTCCAGGTCCTCAGTATCCTAACTACCCACAGGGACAAGGTCAGCAGTATGGAGGATATAGACCAACACAGCCTGGACCACCACAGCCAC
CCCAGCAGAGGCCTTATGGATATGACCAGATCATGCCCAAGAAGCCAGCAGAGGAAGGAAATGATTCGGAGGAAGTGCCAGAAGCATCTG
GCCCACAAAATGATGGGAAAGAGCTGTGCCCCCCGGGAAAACCAACTACCTCTGAGAAGATTCACGAGAGATCTGGAAATAGGGAGGCCC
AAGAAAAGGAAGAGAGACGCGGAACAGCTCATCGGTGGAGCAGTCAGAACACACACAACATTGGTCGATTCAGTTTGTCAACTTCTATGG
GTGCAGTTCATGGTACCCCCAAAACAATTACACACAACAGGGACCCAAAAGGGGGGAACATGCCTGGACCCACAGACTGCGTGAGAGAAA
ACAGCTGGTGATTTATGAAGAGATCAGCGACCCTGAGGAAGATGACGAGTAACTCCCCTCAGGGATACGACACATGCCCATGATGAGAAG
CAGAACGTGGTGACCTTTCACGAACATGGGCATGGCTGCGGACCCCTCGTCATCAGGTGCATAGCAAGTGAAAGCAAGTGTTCACAACAG
TGAAAAGTTGAGCGTCATTTTTCTTAGTGTGCCAAGAGTTCGATGTTAGCGTTTACGTTGTATTTTCTTACACTGTGTCATTCTGTTAGA
TACTAACATTTTCATTGATGAGCAAGACATACTTAATGCATATTTTGGTTTGTGTATCCATGCACCTACCTTAGAAAACAAGTATTGTCG
GTTACCTCTGCATGGAACAGCATTACCCTCCTCTCTCCCCAGATGTGACTACTGAGGGCAGTTCTGAGTGTTTAATTTCAGATTTTTTCC
TCTGCATTTACACACACACGCACACAAACCACACCACACACACACACACACACACACACACACACACACACACACACACACCAAGTACCA
GTATAAGCATCTGCCATCTGCTTTTCCCATTGCCATGCGTCCTGGTCAAGCTCCCCTCACTCTGTTTCCTGGTCAGCATGTACTCCCCTC

>In-frame_ENST00000269137_ENST00000276049_AB012575_SS18_chr18_23612363_-_SSX2B_chrX_52786929_length(amino acids)=549AA_start in transcript=161_stop in transcript=1810
MARVPPSGLPRRPSAWPRSIPPPRIPEVVQPERPASLPQFAVHPERSGLADSGDGGNMSVAFAAPRQRGKGEITPAAIQKMLDDNNHLIQ
CIMDSQNKGKTSECSQYQQMLHTNLVYLATIADSNQNMQSLLPAPPTQNMPMGPGGMNQSGPPPPPRSHNMPSDGMVGGGPPAPHMQNQM
NGQMPGPNHMPMQGPGPNQLNMTNSSMNMPSSSHGSMGGYNHSVPSSQSMPVQNQMTMSQGQPMGNYGPRPNMSMQPNQGPMMHQQPPSQ
QYNMPQGGGQHYQGQQPPMGMMGQVNQGNHMMGQRQIPPYRPPQQGPPQQYSGQEDYYGDQYSHGGQGPPEGMNQQYYPDGNSQYGQQQD
AYQGPPPQQGYPPQQQQYPGQQGYPGQQQGYGPSQGGPGPQYPNYPQGQGQQYGGYRPTQPGPPQPPQQRPYGYDQIMPKKPAEEGNDSE
EVPEASGPQNDGKELCPPGKPTTSEKIHERSGNREAQEKEERRGTAHRWSSQNTHNIGRFSLSTSMGAVHGTPKTITHNRDPKGGNMPGP

--------------------------------------------------------------
>In-frame_ENST00000545952_ENST00000375515_AB012575_SS18_chr18_23612363_-_SSX2B_chrX_52786929_length(transcript)=2152nt_BP=1284nt
ACTTGCCGATAGTGGTGACGGCGGCAACATGTCTGTGGCTTTCGCGGCCCCGAGGCAGCGAGGCAAGGGGGAGATCACTCCCGCTGCGAT
TCAGAAGATGTTGGATGACAATAACCATCTTATTCAGTGTATAATGGACTCTCAGAATAAAGGAAAGACCTCAGAGTGTTCTCAGGTCAT
GAATAAACCACATCTGTTAGTATGGTTTGGTCAGTGGTCCTCAGAAAATCTCATGTCGTGCAACCATACTAATACTCAAGCAAAGGAAAA
CTTGAAGGCCTAGACTGAAACAGGTATCAGCAGATGTTGCACACAAACTTGGTATACCTTGCTACAATAGCAGATTCTAATCAAAATATG
CAGTCTCTTTTACCAGCACCACCCACACAGAATATGCCTATGGGTCCTGGAGGGATGAATCAGAGCGGCCCTCCCCCACCTCCACGCTCT
CACAACATGCCTTCAGATGGAATGGTAGGTGGGGGTCCTCCTGCACCGCACATGCAGAACCAGATGAACGGCCAGATGCCTGGGCCTAAC
CATATGCCTATGCAGGGACCTGGACCCAATCAACTCAATATGACAAACAGTTCCATGAATATGCCTTCAAGTAGCCATGGATCCATGGGA
GGTTACAACCATTCTGTGCCATCATCACAGAGCATGCCAGTACAGAATCAGATGACAATGAGTCAGGGACAACCAATGGGAAACTATGGT
CCCAGACCAAATATGAGTATGCAGCCAAACCAAGGTCCAATGATGCATCAGCAGCCTCCTTCTCAGCAATACAATATGCCACAGGGAGGC
GGACAGCATTACCAAGGACAGCAGCCACCTATGGGAATGATGGGTCAAGTTAACCAAGGCAATCATATGATGGGTCAGAGACAGATTCCT
CCCTATAGACCTCCTCAACAGGGCCCACCACAGCAGTACTCAGGCCAGGAAGACTATTACGGGGACCAATACAGTCATGGTGGACAAGGT
CCTCCAGAAGGCATGAACCAGCAATATTACCCTGATGGAAATTCACAGTATGGCCAACAGCAAGATGCATACCAGGGACCACCTCCACAA
CAGGGATATCCACCCCAGCAGCAGCAGTACCCAGGGCAGCAAGGTTACCCAGGACAGCAGCAGGGCTACGGTCCTTCACAGGGTGGTCCA
GGTCCTCAGTATCCTAACTACCCACAGGGACAAGGTCAGCAGTATGGAGGATATAGACCAACACAGCCTGGACCACCACAGCCACCCCAG
CAGAGGCCTTATGGATATGACCAGATCATGCCCAAGAAGCCAGCAGAGGAAGGAAATGATTCGGAGGAAGTGCCAGAAGCATCTGGCCCA
CAAAATGATGGGAAAGAGCTGTGCCCCCCGGGAAAACCAACTACCTCTGAGAAGATTCACGAGAGATCTGGACCCAAAAGGGGGGAACAT
GCCTGGACCCACAGACTGCGTGAGAGAAAACAGCTGGTGATTTATGAAGAGATCAGCGACCCTGAGGAAGATGACGAGTAACTCCCCTCA
GGGATACGACACATGCCCATGATGAGAAGCAGAACGTGGTGACCTTTCACGAACATGGGCATGGCTGCGGACCCCTCGTCATCAGGTGCA
TAGCAAGTGAAAGCAAGTGTTCACAACAGTGAAAAGTTGAGCGTCATTTTTCTTAGTGTGCCAAGAGTTCGATGTTAGCGTTTACGTTGT
ATTTTCTTACACTGTGTCATTCTGTTAGATACTAACATTTTCATTGATGAGCAAGACATACTTAATGCATATTTTGGTTTGTGTATCCAT
GCACCTACCTTAGAAAACAAGTATTGTCGGTTACCTCTGCATGGAACAGCATTACCCTCCTCTCTCCCCAGATGTGACTACTGAGGGCAG
TTCTGAGTGTTTAATTTCAGATTTTTTCCTCTGCATTTACACACACACGCACACAAACCACACCACACACACACACACACACACACACAC
ACACACACACACACACACACCAAGTACCAGTATAAGCATCTGCCATCTGCTTTTCCCATTGCCATGCGTCCTGGTCAAGCTCCCCTCACT

>In-frame_ENST00000545952_ENST00000375515_AB012575_SS18_chr18_23612363_-_SSX2B_chrX_52786929_length(amino acids)=405AA_start in transcript=303_stop in transcript=1520
MLHTNLVYLATIADSNQNMQSLLPAPPTQNMPMGPGGMNQSGPPPPPRSHNMPSDGMVGGGPPAPHMQNQMNGQMPGPNHMPMQGPGPNQ
LNMTNSSMNMPSSSHGSMGGYNHSVPSSQSMPVQNQMTMSQGQPMGNYGPRPNMSMQPNQGPMMHQQPPSQQYNMPQGGGQHYQGQQPPM
GMMGQVNQGNHMMGQRQIPPYRPPQQGPPQQYSGQEDYYGDQYSHGGQGPPEGMNQQYYPDGNSQYGQQQDAYQGPPPQQGYPPQQQQYP
GQQGYPGQQQGYGPSQGGPGPQYPNYPQGQGQQYGGYRPTQPGPPQPPQQRPYGYDQIMPKKPAEEGNDSEEVPEASGPQNDGKELCPPG

--------------------------------------------------------------
>In-frame_ENST00000545952_ENST00000276049_AB012575_SS18_chr18_23612363_-_SSX2B_chrX_52786929_length(transcript)=2298nt_BP=1284nt
ACTTGCCGATAGTGGTGACGGCGGCAACATGTCTGTGGCTTTCGCGGCCCCGAGGCAGCGAGGCAAGGGGGAGATCACTCCCGCTGCGAT
TCAGAAGATGTTGGATGACAATAACCATCTTATTCAGTGTATAATGGACTCTCAGAATAAAGGAAAGACCTCAGAGTGTTCTCAGGTCAT
GAATAAACCACATCTGTTAGTATGGTTTGGTCAGTGGTCCTCAGAAAATCTCATGTCGTGCAACCATACTAATACTCAAGCAAAGGAAAA
CTTGAAGGCCTAGACTGAAACAGGTATCAGCAGATGTTGCACACAAACTTGGTATACCTTGCTACAATAGCAGATTCTAATCAAAATATG
CAGTCTCTTTTACCAGCACCACCCACACAGAATATGCCTATGGGTCCTGGAGGGATGAATCAGAGCGGCCCTCCCCCACCTCCACGCTCT
CACAACATGCCTTCAGATGGAATGGTAGGTGGGGGTCCTCCTGCACCGCACATGCAGAACCAGATGAACGGCCAGATGCCTGGGCCTAAC
CATATGCCTATGCAGGGACCTGGACCCAATCAACTCAATATGACAAACAGTTCCATGAATATGCCTTCAAGTAGCCATGGATCCATGGGA
GGTTACAACCATTCTGTGCCATCATCACAGAGCATGCCAGTACAGAATCAGATGACAATGAGTCAGGGACAACCAATGGGAAACTATGGT
CCCAGACCAAATATGAGTATGCAGCCAAACCAAGGTCCAATGATGCATCAGCAGCCTCCTTCTCAGCAATACAATATGCCACAGGGAGGC
GGACAGCATTACCAAGGACAGCAGCCACCTATGGGAATGATGGGTCAAGTTAACCAAGGCAATCATATGATGGGTCAGAGACAGATTCCT
CCCTATAGACCTCCTCAACAGGGCCCACCACAGCAGTACTCAGGCCAGGAAGACTATTACGGGGACCAATACAGTCATGGTGGACAAGGT
CCTCCAGAAGGCATGAACCAGCAATATTACCCTGATGGAAATTCACAGTATGGCCAACAGCAAGATGCATACCAGGGACCACCTCCACAA
CAGGGATATCCACCCCAGCAGCAGCAGTACCCAGGGCAGCAAGGTTACCCAGGACAGCAGCAGGGCTACGGTCCTTCACAGGGTGGTCCA
GGTCCTCAGTATCCTAACTACCCACAGGGACAAGGTCAGCAGTATGGAGGATATAGACCAACACAGCCTGGACCACCACAGCCACCCCAG
CAGAGGCCTTATGGATATGACCAGATCATGCCCAAGAAGCCAGCAGAGGAAGGAAATGATTCGGAGGAAGTGCCAGAAGCATCTGGCCCA
CAAAATGATGGGAAAGAGCTGTGCCCCCCGGGAAAACCAACTACCTCTGAGAAGATTCACGAGAGATCTGGAAATAGGGAGGCCCAAGAA
AAGGAAGAGAGACGCGGAACAGCTCATCGGTGGAGCAGTCAGAACACACACAACATTGGTCGATTCAGTTTGTCAACTTCTATGGGTGCA
GTTCATGGTACCCCCAAAACAATTACACACAACAGGGACCCAAAAGGGGGGAACATGCCTGGACCCACAGACTGCGTGAGAGAAAACAGC
TGGTGATTTATGAAGAGATCAGCGACCCTGAGGAAGATGACGAGTAACTCCCCTCAGGGATACGACACATGCCCATGATGAGAAGCAGAA
CGTGGTGACCTTTCACGAACATGGGCATGGCTGCGGACCCCTCGTCATCAGGTGCATAGCAAGTGAAAGCAAGTGTTCACAACAGTGAAA
AGTTGAGCGTCATTTTTCTTAGTGTGCCAAGAGTTCGATGTTAGCGTTTACGTTGTATTTTCTTACACTGTGTCATTCTGTTAGATACTA
ACATTTTCATTGATGAGCAAGACATACTTAATGCATATTTTGGTTTGTGTATCCATGCACCTACCTTAGAAAACAAGTATTGTCGGTTAC
CTCTGCATGGAACAGCATTACCCTCCTCTCTCCCCAGATGTGACTACTGAGGGCAGTTCTGAGTGTTTAATTTCAGATTTTTTCCTCTGC
ATTTACACACACACGCACACAAACCACACCACACACACACACACACACACACACACACACACACACACACACACACCAAGTACCAGTATA
AGCATCTGCCATCTGCTTTTCCCATTGCCATGCGTCCTGGTCAAGCTCCCCTCACTCTGTTTCCTGGTCAGCATGTACTCCCCTCATCCG

>In-frame_ENST00000545952_ENST00000276049_AB012575_SS18_chr18_23612363_-_SSX2B_chrX_52786929_length(amino acids)=440AA_start in transcript=303_stop in transcript=1625
MLHTNLVYLATIADSNQNMQSLLPAPPTQNMPMGPGGMNQSGPPPPPRSHNMPSDGMVGGGPPAPHMQNQMNGQMPGPNHMPMQGPGPNQ
LNMTNSSMNMPSSSHGSMGGYNHSVPSSQSMPVQNQMTMSQGQPMGNYGPRPNMSMQPNQGPMMHQQPPSQQYNMPQGGGQHYQGQQPPM
GMMGQVNQGNHMMGQRQIPPYRPPQQGPPQQYSGQEDYYGDQYSHGGQGPPEGMNQQYYPDGNSQYGQQQDAYQGPPPQQGYPPQQQQYP
GQQGYPGQQQGYGPSQGGPGPQYPNYPQGQGQQYGGYRPTQPGPPQPPQQRPYGYDQIMPKKPAEEGNDSEEVPEASGPQNDGKELCPPG

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for SS18-SSX2B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneSSX2Bchr18:23612363chrX:52786929ENST000002760494925_80110.0416.3333333333333RAB3IP
TgeneSSX2Bchr18:23612363chrX:52786929ENST000003755154825_80110.0372.0RAB3IP
TgeneSSX2Bchr18:23612363chrX:52786929ENST00000276049491_80110.0416.3333333333333SSX2IP
TgeneSSX2Bchr18:23612363chrX:52786929ENST00000375515481_80110.0372.0SSX2IP


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for SS18-SSX2B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for SS18-SSX2B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneSS18C0039101synovial sarcoma2CTD_human;ORPHANET