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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ST6GAL1-EIF4A2 (FusionGDB2 ID:86375)

Fusion Gene Summary for ST6GAL1-EIF4A2

check button Fusion gene summary
Fusion gene informationFusion gene name: ST6GAL1-EIF4A2
Fusion gene ID: 86375
HgeneTgene
Gene symbol

ST6GAL1

EIF4A2

Gene ID

6480

1974

Gene nameST6 beta-galactoside alpha-2,6-sialyltransferase 1eukaryotic translation initiation factor 4A2
SynonymsSIAT1|ST6GalI|ST6NBM-010|DDX2B|EIF4A|EIF4F|eIF-4A-II|eIF4A-II
Cytomap

3q27.3

3q27.3

Type of geneprotein-codingprotein-coding
Descriptionbeta-galactoside alpha-2,6-sialyltransferase 1B-cell antigen CD75CMP-N-acetylneuraminate beta-galactosamide alpha-2,6-sialyltransferaseCMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1ST6 N-acetylgalactosaminide alpha-2,6-sialyleukaryotic initiation factor 4A-IIATP-dependent RNA helicase eIF4A-2
Modification date2020032920200322
UniProtAcc.

Q14240

Ensembl transtripts involved in fusion geneENST00000169298, ENST00000457772, 
ENST00000448044, ENST00000487031, 
ENST00000323963, ENST00000440191, 
ENST00000356531, 
Fusion gene scores* DoF score10 X 7 X 8=56013 X 14 X 6=1092
# samples 1316
** MAII scorelog2(13/560*10)=-2.10691520391651
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(16/1092*10)=-2.77082904603249
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ST6GAL1 [Title/Abstract] AND EIF4A2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointST6GAL1(186769134)-EIF4A2(186505284), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneST6GAL1

GO:0006054

N-acetylneuraminate metabolic process

23999306

HgeneST6GAL1

GO:0018279

protein N-linked glycosylation via asparagine

23999306

HgeneST6GAL1

GO:0097503

sialylation

23999306

TgeneEIF4A2

GO:1900260

negative regulation of RNA-directed 5'-3' RNA polymerase activity

11922617


check buttonFusion gene breakpoints across ST6GAL1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across EIF4A2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-25-1312-01AST6GAL1chr3

186769134

+EIF4A2chr3

186505284

+


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Fusion Gene ORF analysis for ST6GAL1-EIF4A2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000169298ENST00000323963ST6GAL1chr3

186769134

+EIF4A2chr3

186505284

+
In-frameENST00000169298ENST00000440191ST6GAL1chr3

186769134

+EIF4A2chr3

186505284

+
In-frameENST00000169298ENST00000356531ST6GAL1chr3

186769134

+EIF4A2chr3

186505284

+
In-frameENST00000457772ENST00000323963ST6GAL1chr3

186769134

+EIF4A2chr3

186505284

+
In-frameENST00000457772ENST00000440191ST6GAL1chr3

186769134

+EIF4A2chr3

186505284

+
In-frameENST00000457772ENST00000356531ST6GAL1chr3

186769134

+EIF4A2chr3

186505284

+
In-frameENST00000448044ENST00000323963ST6GAL1chr3

186769134

+EIF4A2chr3

186505284

+
In-frameENST00000448044ENST00000440191ST6GAL1chr3

186769134

+EIF4A2chr3

186505284

+
In-frameENST00000448044ENST00000356531ST6GAL1chr3

186769134

+EIF4A2chr3

186505284

+
intron-3CDSENST00000487031ENST00000323963ST6GAL1chr3

186769134

+EIF4A2chr3

186505284

+
intron-3CDSENST00000487031ENST00000440191ST6GAL1chr3

186769134

+EIF4A2chr3

186505284

+
intron-3CDSENST00000487031ENST00000356531ST6GAL1chr3

186769134

+EIF4A2chr3

186505284

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000169298ST6GAL1chr3186769134+ENST00000323963EIF4A2chr3186505284+232513796261693355
ENST00000169298ST6GAL1chr3186769134+ENST00000440191EIF4A2chr3186505284+232213796261693355
ENST00000169298ST6GAL1chr3186769134+ENST00000356531EIF4A2chr3186505284+231913796261693355
ENST00000457772ST6GAL1chr3186769134+ENST00000323963EIF4A2chr3186505284+16276815971199
ENST00000457772ST6GAL1chr3186769134+ENST00000440191EIF4A2chr3186505284+16246815971199
ENST00000457772ST6GAL1chr3186769134+ENST00000356531EIF4A2chr3186505284+16216815971199
ENST00000448044ST6GAL1chr3186769134+ENST00000323963EIF4A2chr3186505284+198210362831350355
ENST00000448044ST6GAL1chr3186769134+ENST00000440191EIF4A2chr3186505284+197910362831350355
ENST00000448044ST6GAL1chr3186769134+ENST00000356531EIF4A2chr3186505284+197610362831350355

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000169298ENST00000323963ST6GAL1chr3186769134+EIF4A2chr3186505284+0.0009941720.99900585
ENST00000169298ENST00000440191ST6GAL1chr3186769134+EIF4A2chr3186505284+0.000998920.9990011
ENST00000169298ENST00000356531ST6GAL1chr3186769134+EIF4A2chr3186505284+0.0010200950.99897987
ENST00000457772ENST00000323963ST6GAL1chr3186769134+EIF4A2chr3186505284+0.0798552260.92014474
ENST00000457772ENST00000440191ST6GAL1chr3186769134+EIF4A2chr3186505284+0.074803720.92519635
ENST00000457772ENST00000356531ST6GAL1chr3186769134+EIF4A2chr3186505284+0.0754818540.92451817
ENST00000448044ENST00000323963ST6GAL1chr3186769134+EIF4A2chr3186505284+0.000476150.9995239
ENST00000448044ENST00000440191ST6GAL1chr3186769134+EIF4A2chr3186505284+0.0004811480.9995189
ENST00000448044ENST00000356531ST6GAL1chr3186769134+EIF4A2chr3186505284+0.0005002270.9994998

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Fusion Genomic Features for ST6GAL1-EIF4A2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ST6GAL1chr3186769134+EIF4A2chr3186505283+2.11E-050.9999789
ST6GAL1chr3186769134+EIF4A2chr3186505283+2.11E-050.9999789

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ST6GAL1-EIF4A2


check button Go to

FGviewer for the breakpoints of chr3:186769134-chr3:186505284

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.EIF4A2

Q14240

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneST6GAL1chr3:186769134chr3:186505284ENST00000169298+581_9235.0407.0Topological domainNote=Cytoplasmic
HgeneST6GAL1chr3:186769134chr3:186505284ENST00000448044+471_9235.0407.0Topological domainNote=Cytoplasmic
HgeneST6GAL1chr3:186769134chr3:186505284ENST00000169298+5810_26235.0407.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneST6GAL1chr3:186769134chr3:186505284ENST00000448044+4710_26235.0407.0TransmembraneHelical%3B Signal-anchor for type II membrane protein

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneST6GAL1chr3:186769134chr3:186505284ENST00000169298+58322_324235.0407.0RegionSubstrate binding
HgeneST6GAL1chr3:186769134chr3:186505284ENST00000448044+47322_324235.0407.0RegionSubstrate binding
HgeneST6GAL1chr3:186769134chr3:186505284ENST00000169298+5827_406235.0407.0Topological domainLumenal
HgeneST6GAL1chr3:186769134chr3:186505284ENST00000448044+4727_406235.0407.0Topological domainLumenal
TgeneEIF4A2chr3:186769134chr3:186505284ENST00000323963711246_407303.0408.0DomainHelicase C-terminal
TgeneEIF4A2chr3:186769134chr3:186505284ENST0000032396371164_235303.0408.0DomainHelicase ATP-binding
TgeneEIF4A2chr3:186769134chr3:186505284ENST00000440191711246_407304.0409.0DomainHelicase C-terminal
TgeneEIF4A2chr3:186769134chr3:186505284ENST0000044019171164_235304.0409.0DomainHelicase ATP-binding
TgeneEIF4A2chr3:186769134chr3:186505284ENST00000323963711183_186303.0408.0MotifNote=DEAD box
TgeneEIF4A2chr3:186769134chr3:186505284ENST0000032396371133_61303.0408.0MotifNote=Q motif
TgeneEIF4A2chr3:186769134chr3:186505284ENST00000440191711183_186304.0409.0MotifNote=DEAD box
TgeneEIF4A2chr3:186769134chr3:186505284ENST0000044019171133_61304.0409.0MotifNote=Q motif
TgeneEIF4A2chr3:186769134chr3:186505284ENST0000032396371177_84303.0408.0Nucleotide bindingATP
TgeneEIF4A2chr3:186769134chr3:186505284ENST0000044019171177_84304.0409.0Nucleotide bindingATP


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Fusion Gene Sequence for ST6GAL1-EIF4A2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000169298_ENST00000323963_TCGA-25-1312-01A_ST6GAL1_chr3_186769134_+_EIF4A2_chr3_186505284_length(transcript)=2325nt_BP=1379nt
GCATACGGAGGCGACTCGCTTCCTTCCCGCCCCTCCGCCGCGCTCTTCTTCCTTCCTTCTCCAGTCCCTTCCACTGTGCGTCTTCTGTCC
CCCGTTCTTCCCCAGCGGACCCCTCTTTCGAGACTCCCTAGTGGGGTCCCCAGCTCCCGGGCGATCCTGCCCTTGCCGAGCGCGTTTTCT
GGAGTCACCTGGGGGAGGGGAGTCCTGGGCAGGGCCGGGCTGGGGAAGACGCCTGGGGCACTGCCCGGCGTTAACAAAGGGAGCCGATAC
CGACCGGCGTGGGCGCGGAGCGGGCGGCCGCCACCGAGCGTGCTGAGCAACCGCAGCCTCCGCGGCCGAGAGTGCAGCGAGCAAGGGGAG
AGCCAGTTGCGCAGAGCCCTGCAACCAGCAGTCCAGGGAGAAGTGGTGAATGTCATGGAGCCCAGCTGAAATGGACTGGCCCCCTTGAGC
CTGTCCCAAGCCCTGGTGCCAGGTGTCCATCCCCGTGCTGAGATGAGTTTTGATCATCCTGAGAAAAATGGGCCTTGGCCTGCAGACCCA
ATAAACCTTCCCTCCCATGGATAATAGTGCTAATTCCTGAGGACCTGAAGGGCCTGCCGCCCCTGGGGGATTAGCCAGAAGCAGGCTTGT
TTTCCTGCTCAGAACAAAGTGACTTCCCTGAACACATCTTCATTATGATTCACACCAACCTGAAGAAAAAGTTCAGCTGCTGCGTCCTGG
TCTTTCTTCTGTTTGCAGTCATCTGTGTGTGGAAGGAAAAGAAGAAAGGGAGTTACTATGATTCCTTTAAATTGCAAACCAAGGAATTCC
AGGTGTTAAAGAGTCTGGGGAAATTGGCCATGGGGTCTGATTCCCAGTCTGTATCCTCAAGCAGCACCCAGGACCCCCACAGGGGCCGCC
AGACCCTCGGCAGTCTCAGAGGCCTAGCCAAGGCCAAACCAGAGGCCTCCTTCCAGGTGTGGAACAAGGACAGCTCTTCCAAAAACCTTA
TCCCTAGGCTGCAAAAGATCTGGAAGAATTACCTAAGCATGAACAAGTACAAAGTGTCCTACAAGGGGCCAGGACCAGGCATCAAGTTCA
GTGCAGAGGCCCTGCGCTGCCACCTCCGGGACCATGTGAATGTATCCATGGTAGAGGTCACAGATTTTCCCTTCAATACCTCTGAATGGG
AGGGTTATCTGCCCAAGGAGAGCATTAGGACCAAGGCTGGGCCTTGGGGCAGGTGTGCTGTTGTGTCGTCAGCGGGATCTCTGAAGTCCT
CCCAACTAGGCAGAGAAATCGATGATCATGACGCAGTCCTGAGGTTTAATGGGGCACCCACAGCCAACTTCCAACAAGATGTGGGCACAA
AAACTACCATTCGCCTGATGAACTCTCAGCATGGTGACATGGACCAGAAGGAGAGAGATGTTATCATGAGGGAATTCCGGTCAGGGTCAA
GTCGTGTTCTGATCACTACTGACTTGTTGGCTCGCGGGATTGATGTGCAACAAGTGTCTTTGGTTATAAATTATGATCTACCTACCAATC
GTGAAAACTATATTCACAGAATTGGCAGAGGGGGTCGATTTGGGAGGAAAGGTGTGGCTATAAACTTTGTTACTGAAGAAGACAAGAGGA
TTCTTCGTGACATTGAGACTTTCTACAATACTACAGTGGAGGAGATGCCCATGAATGTGGCTGACCTTATTTAATTCCTGGGATGAGAGT
TTTGGATGCAGTGCTCGCTGTTGCTGAATAGGCGATCACAACGTGCATTGTGCTTCTTTCTTTGGGAATATTTGAATCTTGTCTCAATGC
TCATAACGGATCAGAAATACAGATTTTGATAGCAAAGCGACGTTAGTCGTGAGCTCTTGTGAGGAAAGTCATTGGCTTTATCCTCTTTAG
AGTTAGACTGTTGGGGTGGGTATAAAAGATGGGGTCTGTAAAATCTTTCTTTCTTAGAAATTTATTTCCTAGTTCTGTAGAAATGGTTGT
ATTAGATGTTCTCTATCATTTAATAATATACTTGTGGACTAAAAGATATAAGTGCTGTATAAAATCAGCCAATTATGTTAAACTAGCATA
TCTGCCTTTATTGTGTTTGTCATTAGCCTGAGTAGAAAGGCCTTTAAAATTTTTTTAGAAAGCATTTGAATGCATTTTGTTTGGTATTGT
ATTTATTCAATAAAGTATTTAATTAGTGCTAAGTGTGAACTGGACCCTGTTGCTAAGCCCCAGCAAGCAATCCTAGGTAGGGTTTAATCC

>In-frame_ENST00000169298_ENST00000323963_TCGA-25-1312-01A_ST6GAL1_chr3_186769134_+_EIF4A2_chr3_186505284_length(amino acids)=355AA_start in transcript=626_stop in transcript=1693
MFSCSEQSDFPEHIFIMIHTNLKKKFSCCVLVFLLFAVICVWKEKKKGSYYDSFKLQTKEFQVLKSLGKLAMGSDSQSVSSSSTQDPHRG
RQTLGSLRGLAKAKPEASFQVWNKDSSSKNLIPRLQKIWKNYLSMNKYKVSYKGPGPGIKFSAEALRCHLRDHVNVSMVEVTDFPFNTSE
WEGYLPKESIRTKAGPWGRCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQHGDMDQKERDVIMREFRSG

--------------------------------------------------------------
>In-frame_ENST00000169298_ENST00000440191_TCGA-25-1312-01A_ST6GAL1_chr3_186769134_+_EIF4A2_chr3_186505284_length(transcript)=2322nt_BP=1379nt
GCATACGGAGGCGACTCGCTTCCTTCCCGCCCCTCCGCCGCGCTCTTCTTCCTTCCTTCTCCAGTCCCTTCCACTGTGCGTCTTCTGTCC
CCCGTTCTTCCCCAGCGGACCCCTCTTTCGAGACTCCCTAGTGGGGTCCCCAGCTCCCGGGCGATCCTGCCCTTGCCGAGCGCGTTTTCT
GGAGTCACCTGGGGGAGGGGAGTCCTGGGCAGGGCCGGGCTGGGGAAGACGCCTGGGGCACTGCCCGGCGTTAACAAAGGGAGCCGATAC
CGACCGGCGTGGGCGCGGAGCGGGCGGCCGCCACCGAGCGTGCTGAGCAACCGCAGCCTCCGCGGCCGAGAGTGCAGCGAGCAAGGGGAG
AGCCAGTTGCGCAGAGCCCTGCAACCAGCAGTCCAGGGAGAAGTGGTGAATGTCATGGAGCCCAGCTGAAATGGACTGGCCCCCTTGAGC
CTGTCCCAAGCCCTGGTGCCAGGTGTCCATCCCCGTGCTGAGATGAGTTTTGATCATCCTGAGAAAAATGGGCCTTGGCCTGCAGACCCA
ATAAACCTTCCCTCCCATGGATAATAGTGCTAATTCCTGAGGACCTGAAGGGCCTGCCGCCCCTGGGGGATTAGCCAGAAGCAGGCTTGT
TTTCCTGCTCAGAACAAAGTGACTTCCCTGAACACATCTTCATTATGATTCACACCAACCTGAAGAAAAAGTTCAGCTGCTGCGTCCTGG
TCTTTCTTCTGTTTGCAGTCATCTGTGTGTGGAAGGAAAAGAAGAAAGGGAGTTACTATGATTCCTTTAAATTGCAAACCAAGGAATTCC
AGGTGTTAAAGAGTCTGGGGAAATTGGCCATGGGGTCTGATTCCCAGTCTGTATCCTCAAGCAGCACCCAGGACCCCCACAGGGGCCGCC
AGACCCTCGGCAGTCTCAGAGGCCTAGCCAAGGCCAAACCAGAGGCCTCCTTCCAGGTGTGGAACAAGGACAGCTCTTCCAAAAACCTTA
TCCCTAGGCTGCAAAAGATCTGGAAGAATTACCTAAGCATGAACAAGTACAAAGTGTCCTACAAGGGGCCAGGACCAGGCATCAAGTTCA
GTGCAGAGGCCCTGCGCTGCCACCTCCGGGACCATGTGAATGTATCCATGGTAGAGGTCACAGATTTTCCCTTCAATACCTCTGAATGGG
AGGGTTATCTGCCCAAGGAGAGCATTAGGACCAAGGCTGGGCCTTGGGGCAGGTGTGCTGTTGTGTCGTCAGCGGGATCTCTGAAGTCCT
CCCAACTAGGCAGAGAAATCGATGATCATGACGCAGTCCTGAGGTTTAATGGGGCACCCACAGCCAACTTCCAACAAGATGTGGGCACAA
AAACTACCATTCGCCTGATGAACTCTCAGCATGGTGACATGGACCAGAAGGAGAGAGATGTTATCATGAGGGAATTCCGGTCAGGGTCAA
GTCGTGTTCTGATCACTACTGACTTGTTGGCTCGCGGGATTGATGTGCAACAAGTGTCTTTGGTTATAAATTATGATCTACCTACCAATC
GTGAAAACTATATTCACAGAATTGGCAGAGGGGGTCGATTTGGGAGGAAAGGTGTGGCTATAAACTTTGTTACTGAAGAAGACAAGAGGA
TTCTTCGTGACATTGAGACTTTCTACAATACTACAGTGGAGGAGATGCCCATGAATGTGGCTGACCTTATTTAATTCCTGGGATGAGAGT
TTTGGATGCAGTGCTCGCTGTTGCTGAATAGGCGATCACAACGTGCATTGTGCTTCTTTCTTTGGGAATATTTGAATCTTGTCTCAATGC
TCATAACGGATCAGAAATACAGATTTTGATAGCAAAGCGACGTTAGTCGTGAGCTCTTGTGAGGAAAGTCATTGGCTTTATCCTCTTTAG
AGTTAGACTGTTGGGGTGGGTATAAAAGATGGGGTCTGTAAAATCTTTCTTTCTTAGAAATTTATTTCCTAGTTCTGTAGAAATGGTTGT
ATTAGATGTTCTCTATCATTTAATAATATACTTGTGGACTAAAAGATATAAGTGCTGTATAAAATCAGCCAATTATGTTAAACTAGCATA
TCTGCCTTTATTGTGTTTGTCATTAGCCTGAGTAGAAAGGCCTTTAAAATTTTTTTAGAAAGCATTTGAATGCATTTTGTTTGGTATTGT
ATTTATTCAATAAAGTATTTAATTAGTGCTAAGTGTGAACTGGACCCTGTTGCTAAGCCCCAGCAAGCAATCCTAGGTAGGGTTTAATCC

>In-frame_ENST00000169298_ENST00000440191_TCGA-25-1312-01A_ST6GAL1_chr3_186769134_+_EIF4A2_chr3_186505284_length(amino acids)=355AA_start in transcript=626_stop in transcript=1693
MFSCSEQSDFPEHIFIMIHTNLKKKFSCCVLVFLLFAVICVWKEKKKGSYYDSFKLQTKEFQVLKSLGKLAMGSDSQSVSSSSTQDPHRG
RQTLGSLRGLAKAKPEASFQVWNKDSSSKNLIPRLQKIWKNYLSMNKYKVSYKGPGPGIKFSAEALRCHLRDHVNVSMVEVTDFPFNTSE
WEGYLPKESIRTKAGPWGRCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQHGDMDQKERDVIMREFRSG

--------------------------------------------------------------
>In-frame_ENST00000169298_ENST00000356531_TCGA-25-1312-01A_ST6GAL1_chr3_186769134_+_EIF4A2_chr3_186505284_length(transcript)=2319nt_BP=1379nt
GCATACGGAGGCGACTCGCTTCCTTCCCGCCCCTCCGCCGCGCTCTTCTTCCTTCCTTCTCCAGTCCCTTCCACTGTGCGTCTTCTGTCC
CCCGTTCTTCCCCAGCGGACCCCTCTTTCGAGACTCCCTAGTGGGGTCCCCAGCTCCCGGGCGATCCTGCCCTTGCCGAGCGCGTTTTCT
GGAGTCACCTGGGGGAGGGGAGTCCTGGGCAGGGCCGGGCTGGGGAAGACGCCTGGGGCACTGCCCGGCGTTAACAAAGGGAGCCGATAC
CGACCGGCGTGGGCGCGGAGCGGGCGGCCGCCACCGAGCGTGCTGAGCAACCGCAGCCTCCGCGGCCGAGAGTGCAGCGAGCAAGGGGAG
AGCCAGTTGCGCAGAGCCCTGCAACCAGCAGTCCAGGGAGAAGTGGTGAATGTCATGGAGCCCAGCTGAAATGGACTGGCCCCCTTGAGC
CTGTCCCAAGCCCTGGTGCCAGGTGTCCATCCCCGTGCTGAGATGAGTTTTGATCATCCTGAGAAAAATGGGCCTTGGCCTGCAGACCCA
ATAAACCTTCCCTCCCATGGATAATAGTGCTAATTCCTGAGGACCTGAAGGGCCTGCCGCCCCTGGGGGATTAGCCAGAAGCAGGCTTGT
TTTCCTGCTCAGAACAAAGTGACTTCCCTGAACACATCTTCATTATGATTCACACCAACCTGAAGAAAAAGTTCAGCTGCTGCGTCCTGG
TCTTTCTTCTGTTTGCAGTCATCTGTGTGTGGAAGGAAAAGAAGAAAGGGAGTTACTATGATTCCTTTAAATTGCAAACCAAGGAATTCC
AGGTGTTAAAGAGTCTGGGGAAATTGGCCATGGGGTCTGATTCCCAGTCTGTATCCTCAAGCAGCACCCAGGACCCCCACAGGGGCCGCC
AGACCCTCGGCAGTCTCAGAGGCCTAGCCAAGGCCAAACCAGAGGCCTCCTTCCAGGTGTGGAACAAGGACAGCTCTTCCAAAAACCTTA
TCCCTAGGCTGCAAAAGATCTGGAAGAATTACCTAAGCATGAACAAGTACAAAGTGTCCTACAAGGGGCCAGGACCAGGCATCAAGTTCA
GTGCAGAGGCCCTGCGCTGCCACCTCCGGGACCATGTGAATGTATCCATGGTAGAGGTCACAGATTTTCCCTTCAATACCTCTGAATGGG
AGGGTTATCTGCCCAAGGAGAGCATTAGGACCAAGGCTGGGCCTTGGGGCAGGTGTGCTGTTGTGTCGTCAGCGGGATCTCTGAAGTCCT
CCCAACTAGGCAGAGAAATCGATGATCATGACGCAGTCCTGAGGTTTAATGGGGCACCCACAGCCAACTTCCAACAAGATGTGGGCACAA
AAACTACCATTCGCCTGATGAACTCTCAGCATGGTGACATGGACCAGAAGGAGAGAGATGTTATCATGAGGGAATTCCGGTCAGGGTCAA
GTCGTGTTCTGATCACTACTGACTTGTTGGCTCGCGGGATTGATGTGCAACAAGTGTCTTTGGTTATAAATTATGATCTACCTACCAATC
GTGAAAACTATATTCACAGAATTGGCAGAGGGGGTCGATTTGGGAGGAAAGGTGTGGCTATAAACTTTGTTACTGAAGAAGACAAGAGGA
TTCTTCGTGACATTGAGACTTTCTACAATACTACAGTGGAGGAGATGCCCATGAATGTGGCTGACCTTATTTAATTCCTGGGATGAGAGT
TTTGGATGCAGTGCTCGCTGTTGCTGAATAGGCGATCACAACGTGCATTGTGCTTCTTTCTTTGGGAATATTTGAATCTTGTCTCAATGC
TCATAACGGATCAGAAATACAGATTTTGATAGCAAAGCGACGTTAGTCGTGAGCTCTTGTGAGGAAAGTCATTGGCTTTATCCTCTTTAG
AGTTAGACTGTTGGGGTGGGTATAAAAGATGGGGTCTGTAAAATCTTTCTTTCTTAGAAATTTATTTCCTAGTTCTGTAGAAATGGTTGT
ATTAGATGTTCTCTATCATTTAATAATATACTTGTGGACTAAAAGATATAAGTGCTGTATAAAATCAGCCAATTATGTTAAACTAGCATA
TCTGCCTTTATTGTGTTTGTCATTAGCCTGAGTAGAAAGGCCTTTAAAATTTTTTTAGAAAGCATTTGAATGCATTTTGTTTGGTATTGT
ATTTATTCAATAAAGTATTTAATTAGTGCTAAGTGTGAACTGGACCCTGTTGCTAAGCCCCAGCAAGCAATCCTAGGTAGGGTTTAATCC

>In-frame_ENST00000169298_ENST00000356531_TCGA-25-1312-01A_ST6GAL1_chr3_186769134_+_EIF4A2_chr3_186505284_length(amino acids)=355AA_start in transcript=626_stop in transcript=1693
MFSCSEQSDFPEHIFIMIHTNLKKKFSCCVLVFLLFAVICVWKEKKKGSYYDSFKLQTKEFQVLKSLGKLAMGSDSQSVSSSSTQDPHRG
RQTLGSLRGLAKAKPEASFQVWNKDSSSKNLIPRLQKIWKNYLSMNKYKVSYKGPGPGIKFSAEALRCHLRDHVNVSMVEVTDFPFNTSE
WEGYLPKESIRTKAGPWGRCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQHGDMDQKERDVIMREFRSG

--------------------------------------------------------------
>In-frame_ENST00000457772_ENST00000323963_TCGA-25-1312-01A_ST6GAL1_chr3_186769134_+_EIF4A2_chr3_186505284_length(transcript)=1627nt_BP=681nt
GCTCTTCTTCCTTCCTTCTCCAGTCCCTTCCACTGTGCGTCTTCTGTCCCCCGTTCTTCCCCAGCGGACCCCTCTTTCGAGACTCCCTAG
TGGGGTCCCCAGCTCCCGGGCGATCCTGCCCTTGCCGAGCGCGTTTTCTGGAGTCACCTGGGGGAGGGGAGTCCTGGGCAGGGCCGGGCT
GGGGAAGACGCCTGGGGCACTGCCCGGCGTTAACAAAGGGAGCCGATACCGACCGGCGTGGGCGCGGAGCGGGCGGCCGCCACCGAGCGT
GCTGAGCAACCGCAGCCTCCGCGGCCGAGAGTGCAGCGAGCAAGGGGAGAGCCAGTTGCGCAGAGCCCTGCAACCAGCAGTCCAGGGAGA
AGTGGTGAATGTCATGGAGCCCAGCTGAAATGGACTGGCCCCCTTGAGCCTGTCCCAAGCCCTGGTGCCAGGTGTCCATCCCCGTGCTGA
GATGAGTTTTGATCATCCTGAGAAAAATGGGCCTTGGCCTGCAGACCCAATAAACCTTCCCTCCCATGGATAATAGTGCTAATTCCTGAG
GACCTGAAGGGCCTGCCGCCCCTGGGGGATTAGCCAGAAGCAGATGATCATGACGCAGTCCTGAGGTTTAATGGGGCACCCACAGCCAAC
TTCCAACAAGATGTGGGCACAAAAACTACCATTCGCCTGATGAACTCTCAGCATGGTGACATGGACCAGAAGGAGAGAGATGTTATCATG
AGGGAATTCCGGTCAGGGTCAAGTCGTGTTCTGATCACTACTGACTTGTTGGCTCGCGGGATTGATGTGCAACAAGTGTCTTTGGTTATA
AATTATGATCTACCTACCAATCGTGAAAACTATATTCACAGAATTGGCAGAGGGGGTCGATTTGGGAGGAAAGGTGTGGCTATAAACTTT
GTTACTGAAGAAGACAAGAGGATTCTTCGTGACATTGAGACTTTCTACAATACTACAGTGGAGGAGATGCCCATGAATGTGGCTGACCTT
ATTTAATTCCTGGGATGAGAGTTTTGGATGCAGTGCTCGCTGTTGCTGAATAGGCGATCACAACGTGCATTGTGCTTCTTTCTTTGGGAA
TATTTGAATCTTGTCTCAATGCTCATAACGGATCAGAAATACAGATTTTGATAGCAAAGCGACGTTAGTCGTGAGCTCTTGTGAGGAAAG
TCATTGGCTTTATCCTCTTTAGAGTTAGACTGTTGGGGTGGGTATAAAAGATGGGGTCTGTAAAATCTTTCTTTCTTAGAAATTTATTTC
CTAGTTCTGTAGAAATGGTTGTATTAGATGTTCTCTATCATTTAATAATATACTTGTGGACTAAAAGATATAAGTGCTGTATAAAATCAG
CCAATTATGTTAAACTAGCATATCTGCCTTTATTGTGTTTGTCATTAGCCTGAGTAGAAAGGCCTTTAAAATTTTTTTAGAAAGCATTTG
AATGCATTTTGTTTGGTATTGTATTTATTCAATAAAGTATTTAATTAGTGCTAAGTGTGAACTGGACCCTGTTGCTAAGCCCCAGCAAGC
AATCCTAGGTAGGGTTTAATCCCCAGTAAAATTGCCATATTGCACATGTCTTAATGAAGTTTGAATGTTAAATAAATTGTATATTCACTT

>In-frame_ENST00000457772_ENST00000323963_TCGA-25-1312-01A_ST6GAL1_chr3_186769134_+_EIF4A2_chr3_186505284_length(amino acids)=199AA_start in transcript=597_stop in transcript=1
MRHDHLLLANPPGAAGPSGPQELALLSMGGKVYWVCRPRPIFLRMIKTHLSTGMDTWHQGLGQAQGGQSISAGLHDIHHFSLDCWLQGSA
QLALPLLAALSAAEAAVAQHARWRPPAPRPRRSVSAPFVNAGQCPRRLPQPGPAQDSPPPGDSRKRARQGQDRPGAGDPTRESRKRGPLG

--------------------------------------------------------------
>In-frame_ENST00000457772_ENST00000440191_TCGA-25-1312-01A_ST6GAL1_chr3_186769134_+_EIF4A2_chr3_186505284_length(transcript)=1624nt_BP=681nt
GCTCTTCTTCCTTCCTTCTCCAGTCCCTTCCACTGTGCGTCTTCTGTCCCCCGTTCTTCCCCAGCGGACCCCTCTTTCGAGACTCCCTAG
TGGGGTCCCCAGCTCCCGGGCGATCCTGCCCTTGCCGAGCGCGTTTTCTGGAGTCACCTGGGGGAGGGGAGTCCTGGGCAGGGCCGGGCT
GGGGAAGACGCCTGGGGCACTGCCCGGCGTTAACAAAGGGAGCCGATACCGACCGGCGTGGGCGCGGAGCGGGCGGCCGCCACCGAGCGT
GCTGAGCAACCGCAGCCTCCGCGGCCGAGAGTGCAGCGAGCAAGGGGAGAGCCAGTTGCGCAGAGCCCTGCAACCAGCAGTCCAGGGAGA
AGTGGTGAATGTCATGGAGCCCAGCTGAAATGGACTGGCCCCCTTGAGCCTGTCCCAAGCCCTGGTGCCAGGTGTCCATCCCCGTGCTGA
GATGAGTTTTGATCATCCTGAGAAAAATGGGCCTTGGCCTGCAGACCCAATAAACCTTCCCTCCCATGGATAATAGTGCTAATTCCTGAG
GACCTGAAGGGCCTGCCGCCCCTGGGGGATTAGCCAGAAGCAGATGATCATGACGCAGTCCTGAGGTTTAATGGGGCACCCACAGCCAAC
TTCCAACAAGATGTGGGCACAAAAACTACCATTCGCCTGATGAACTCTCAGCATGGTGACATGGACCAGAAGGAGAGAGATGTTATCATG
AGGGAATTCCGGTCAGGGTCAAGTCGTGTTCTGATCACTACTGACTTGTTGGCTCGCGGGATTGATGTGCAACAAGTGTCTTTGGTTATA
AATTATGATCTACCTACCAATCGTGAAAACTATATTCACAGAATTGGCAGAGGGGGTCGATTTGGGAGGAAAGGTGTGGCTATAAACTTT
GTTACTGAAGAAGACAAGAGGATTCTTCGTGACATTGAGACTTTCTACAATACTACAGTGGAGGAGATGCCCATGAATGTGGCTGACCTT
ATTTAATTCCTGGGATGAGAGTTTTGGATGCAGTGCTCGCTGTTGCTGAATAGGCGATCACAACGTGCATTGTGCTTCTTTCTTTGGGAA
TATTTGAATCTTGTCTCAATGCTCATAACGGATCAGAAATACAGATTTTGATAGCAAAGCGACGTTAGTCGTGAGCTCTTGTGAGGAAAG
TCATTGGCTTTATCCTCTTTAGAGTTAGACTGTTGGGGTGGGTATAAAAGATGGGGTCTGTAAAATCTTTCTTTCTTAGAAATTTATTTC
CTAGTTCTGTAGAAATGGTTGTATTAGATGTTCTCTATCATTTAATAATATACTTGTGGACTAAAAGATATAAGTGCTGTATAAAATCAG
CCAATTATGTTAAACTAGCATATCTGCCTTTATTGTGTTTGTCATTAGCCTGAGTAGAAAGGCCTTTAAAATTTTTTTAGAAAGCATTTG
AATGCATTTTGTTTGGTATTGTATTTATTCAATAAAGTATTTAATTAGTGCTAAGTGTGAACTGGACCCTGTTGCTAAGCCCCAGCAAGC
AATCCTAGGTAGGGTTTAATCCCCAGTAAAATTGCCATATTGCACATGTCTTAATGAAGTTTGAATGTTAAATAAATTGTATATTCACTT

>In-frame_ENST00000457772_ENST00000440191_TCGA-25-1312-01A_ST6GAL1_chr3_186769134_+_EIF4A2_chr3_186505284_length(amino acids)=199AA_start in transcript=597_stop in transcript=1
MRHDHLLLANPPGAAGPSGPQELALLSMGGKVYWVCRPRPIFLRMIKTHLSTGMDTWHQGLGQAQGGQSISAGLHDIHHFSLDCWLQGSA
QLALPLLAALSAAEAAVAQHARWRPPAPRPRRSVSAPFVNAGQCPRRLPQPGPAQDSPPPGDSRKRARQGQDRPGAGDPTRESRKRGPLG

--------------------------------------------------------------
>In-frame_ENST00000457772_ENST00000356531_TCGA-25-1312-01A_ST6GAL1_chr3_186769134_+_EIF4A2_chr3_186505284_length(transcript)=1621nt_BP=681nt
GCTCTTCTTCCTTCCTTCTCCAGTCCCTTCCACTGTGCGTCTTCTGTCCCCCGTTCTTCCCCAGCGGACCCCTCTTTCGAGACTCCCTAG
TGGGGTCCCCAGCTCCCGGGCGATCCTGCCCTTGCCGAGCGCGTTTTCTGGAGTCACCTGGGGGAGGGGAGTCCTGGGCAGGGCCGGGCT
GGGGAAGACGCCTGGGGCACTGCCCGGCGTTAACAAAGGGAGCCGATACCGACCGGCGTGGGCGCGGAGCGGGCGGCCGCCACCGAGCGT
GCTGAGCAACCGCAGCCTCCGCGGCCGAGAGTGCAGCGAGCAAGGGGAGAGCCAGTTGCGCAGAGCCCTGCAACCAGCAGTCCAGGGAGA
AGTGGTGAATGTCATGGAGCCCAGCTGAAATGGACTGGCCCCCTTGAGCCTGTCCCAAGCCCTGGTGCCAGGTGTCCATCCCCGTGCTGA
GATGAGTTTTGATCATCCTGAGAAAAATGGGCCTTGGCCTGCAGACCCAATAAACCTTCCCTCCCATGGATAATAGTGCTAATTCCTGAG
GACCTGAAGGGCCTGCCGCCCCTGGGGGATTAGCCAGAAGCAGATGATCATGACGCAGTCCTGAGGTTTAATGGGGCACCCACAGCCAAC
TTCCAACAAGATGTGGGCACAAAAACTACCATTCGCCTGATGAACTCTCAGCATGGTGACATGGACCAGAAGGAGAGAGATGTTATCATG
AGGGAATTCCGGTCAGGGTCAAGTCGTGTTCTGATCACTACTGACTTGTTGGCTCGCGGGATTGATGTGCAACAAGTGTCTTTGGTTATA
AATTATGATCTACCTACCAATCGTGAAAACTATATTCACAGAATTGGCAGAGGGGGTCGATTTGGGAGGAAAGGTGTGGCTATAAACTTT
GTTACTGAAGAAGACAAGAGGATTCTTCGTGACATTGAGACTTTCTACAATACTACAGTGGAGGAGATGCCCATGAATGTGGCTGACCTT
ATTTAATTCCTGGGATGAGAGTTTTGGATGCAGTGCTCGCTGTTGCTGAATAGGCGATCACAACGTGCATTGTGCTTCTTTCTTTGGGAA
TATTTGAATCTTGTCTCAATGCTCATAACGGATCAGAAATACAGATTTTGATAGCAAAGCGACGTTAGTCGTGAGCTCTTGTGAGGAAAG
TCATTGGCTTTATCCTCTTTAGAGTTAGACTGTTGGGGTGGGTATAAAAGATGGGGTCTGTAAAATCTTTCTTTCTTAGAAATTTATTTC
CTAGTTCTGTAGAAATGGTTGTATTAGATGTTCTCTATCATTTAATAATATACTTGTGGACTAAAAGATATAAGTGCTGTATAAAATCAG
CCAATTATGTTAAACTAGCATATCTGCCTTTATTGTGTTTGTCATTAGCCTGAGTAGAAAGGCCTTTAAAATTTTTTTAGAAAGCATTTG
AATGCATTTTGTTTGGTATTGTATTTATTCAATAAAGTATTTAATTAGTGCTAAGTGTGAACTGGACCCTGTTGCTAAGCCCCAGCAAGC
AATCCTAGGTAGGGTTTAATCCCCAGTAAAATTGCCATATTGCACATGTCTTAATGAAGTTTGAATGTTAAATAAATTGTATATTCACTT

>In-frame_ENST00000457772_ENST00000356531_TCGA-25-1312-01A_ST6GAL1_chr3_186769134_+_EIF4A2_chr3_186505284_length(amino acids)=199AA_start in transcript=597_stop in transcript=1
MRHDHLLLANPPGAAGPSGPQELALLSMGGKVYWVCRPRPIFLRMIKTHLSTGMDTWHQGLGQAQGGQSISAGLHDIHHFSLDCWLQGSA
QLALPLLAALSAAEAAVAQHARWRPPAPRPRRSVSAPFVNAGQCPRRLPQPGPAQDSPPPGDSRKRARQGQDRPGAGDPTRESRKRGPLG

--------------------------------------------------------------
>In-frame_ENST00000448044_ENST00000323963_TCGA-25-1312-01A_ST6GAL1_chr3_186769134_+_EIF4A2_chr3_186505284_length(transcript)=1982nt_BP=1036nt
AACTTTCTGATAGCTTAATAGGAGGAGGTTCCTGTAGGGCGGCACAACCAGGGAGGGCGTGGAAGCTCTGCATCCCTTCTCCCATACCTT
GCTCTACACATCTCTTCATCTGTATCCTCTGCAGCATCCTTGATGATAAACCAGTAAATATGAGTTTTGATCATCCTGAGAAAAATGGGC
CTTGGCCTGCAGACCCAATAAACCTTCCCTCCCATGGATAATAGTGCTAATTCCTGAGGACCTGAAGGGCCTGCCGCCCCTGGGGGATTA
GCCAGAAGCAGGCTTGTTTTCCTGCTCAGAACAAAGTGACTTCCCTGAACACATCTTCATTATGATTCACACCAACCTGAAGAAAAAGTT
CAGCTGCTGCGTCCTGGTCTTTCTTCTGTTTGCAGTCATCTGTGTGTGGAAGGAAAAGAAGAAAGGGAGTTACTATGATTCCTTTAAATT
GCAAACCAAGGAATTCCAGGTGTTAAAGAGTCTGGGGAAATTGGCCATGGGGTCTGATTCCCAGTCTGTATCCTCAAGCAGCACCCAGGA
CCCCCACAGGGGCCGCCAGACCCTCGGCAGTCTCAGAGGCCTAGCCAAGGCCAAACCAGAGGCCTCCTTCCAGGTGTGGAACAAGGACAG
CTCTTCCAAAAACCTTATCCCTAGGCTGCAAAAGATCTGGAAGAATTACCTAAGCATGAACAAGTACAAAGTGTCCTACAAGGGGCCAGG
ACCAGGCATCAAGTTCAGTGCAGAGGCCCTGCGCTGCCACCTCCGGGACCATGTGAATGTATCCATGGTAGAGGTCACAGATTTTCCCTT
CAATACCTCTGAATGGGAGGGTTATCTGCCCAAGGAGAGCATTAGGACCAAGGCTGGGCCTTGGGGCAGGTGTGCTGTTGTGTCGTCAGC
GGGATCTCTGAAGTCCTCCCAACTAGGCAGAGAAATCGATGATCATGACGCAGTCCTGAGGTTTAATGGGGCACCCACAGCCAACTTCCA
ACAAGATGTGGGCACAAAAACTACCATTCGCCTGATGAACTCTCAGCATGGTGACATGGACCAGAAGGAGAGAGATGTTATCATGAGGGA
ATTCCGGTCAGGGTCAAGTCGTGTTCTGATCACTACTGACTTGTTGGCTCGCGGGATTGATGTGCAACAAGTGTCTTTGGTTATAAATTA
TGATCTACCTACCAATCGTGAAAACTATATTCACAGAATTGGCAGAGGGGGTCGATTTGGGAGGAAAGGTGTGGCTATAAACTTTGTTAC
TGAAGAAGACAAGAGGATTCTTCGTGACATTGAGACTTTCTACAATACTACAGTGGAGGAGATGCCCATGAATGTGGCTGACCTTATTTA
ATTCCTGGGATGAGAGTTTTGGATGCAGTGCTCGCTGTTGCTGAATAGGCGATCACAACGTGCATTGTGCTTCTTTCTTTGGGAATATTT
GAATCTTGTCTCAATGCTCATAACGGATCAGAAATACAGATTTTGATAGCAAAGCGACGTTAGTCGTGAGCTCTTGTGAGGAAAGTCATT
GGCTTTATCCTCTTTAGAGTTAGACTGTTGGGGTGGGTATAAAAGATGGGGTCTGTAAAATCTTTCTTTCTTAGAAATTTATTTCCTAGT
TCTGTAGAAATGGTTGTATTAGATGTTCTCTATCATTTAATAATATACTTGTGGACTAAAAGATATAAGTGCTGTATAAAATCAGCCAAT
TATGTTAAACTAGCATATCTGCCTTTATTGTGTTTGTCATTAGCCTGAGTAGAAAGGCCTTTAAAATTTTTTTAGAAAGCATTTGAATGC
ATTTTGTTTGGTATTGTATTTATTCAATAAAGTATTTAATTAGTGCTAAGTGTGAACTGGACCCTGTTGCTAAGCCCCAGCAAGCAATCC
TAGGTAGGGTTTAATCCCCAGTAAAATTGCCATATTGCACATGTCTTAATGAAGTTTGAATGTTAAATAAATTGTATATTCACTTTAAAG

>In-frame_ENST00000448044_ENST00000323963_TCGA-25-1312-01A_ST6GAL1_chr3_186769134_+_EIF4A2_chr3_186505284_length(amino acids)=355AA_start in transcript=283_stop in transcript=1350
MFSCSEQSDFPEHIFIMIHTNLKKKFSCCVLVFLLFAVICVWKEKKKGSYYDSFKLQTKEFQVLKSLGKLAMGSDSQSVSSSSTQDPHRG
RQTLGSLRGLAKAKPEASFQVWNKDSSSKNLIPRLQKIWKNYLSMNKYKVSYKGPGPGIKFSAEALRCHLRDHVNVSMVEVTDFPFNTSE
WEGYLPKESIRTKAGPWGRCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQHGDMDQKERDVIMREFRSG

--------------------------------------------------------------
>In-frame_ENST00000448044_ENST00000440191_TCGA-25-1312-01A_ST6GAL1_chr3_186769134_+_EIF4A2_chr3_186505284_length(transcript)=1979nt_BP=1036nt
AACTTTCTGATAGCTTAATAGGAGGAGGTTCCTGTAGGGCGGCACAACCAGGGAGGGCGTGGAAGCTCTGCATCCCTTCTCCCATACCTT
GCTCTACACATCTCTTCATCTGTATCCTCTGCAGCATCCTTGATGATAAACCAGTAAATATGAGTTTTGATCATCCTGAGAAAAATGGGC
CTTGGCCTGCAGACCCAATAAACCTTCCCTCCCATGGATAATAGTGCTAATTCCTGAGGACCTGAAGGGCCTGCCGCCCCTGGGGGATTA
GCCAGAAGCAGGCTTGTTTTCCTGCTCAGAACAAAGTGACTTCCCTGAACACATCTTCATTATGATTCACACCAACCTGAAGAAAAAGTT
CAGCTGCTGCGTCCTGGTCTTTCTTCTGTTTGCAGTCATCTGTGTGTGGAAGGAAAAGAAGAAAGGGAGTTACTATGATTCCTTTAAATT
GCAAACCAAGGAATTCCAGGTGTTAAAGAGTCTGGGGAAATTGGCCATGGGGTCTGATTCCCAGTCTGTATCCTCAAGCAGCACCCAGGA
CCCCCACAGGGGCCGCCAGACCCTCGGCAGTCTCAGAGGCCTAGCCAAGGCCAAACCAGAGGCCTCCTTCCAGGTGTGGAACAAGGACAG
CTCTTCCAAAAACCTTATCCCTAGGCTGCAAAAGATCTGGAAGAATTACCTAAGCATGAACAAGTACAAAGTGTCCTACAAGGGGCCAGG
ACCAGGCATCAAGTTCAGTGCAGAGGCCCTGCGCTGCCACCTCCGGGACCATGTGAATGTATCCATGGTAGAGGTCACAGATTTTCCCTT
CAATACCTCTGAATGGGAGGGTTATCTGCCCAAGGAGAGCATTAGGACCAAGGCTGGGCCTTGGGGCAGGTGTGCTGTTGTGTCGTCAGC
GGGATCTCTGAAGTCCTCCCAACTAGGCAGAGAAATCGATGATCATGACGCAGTCCTGAGGTTTAATGGGGCACCCACAGCCAACTTCCA
ACAAGATGTGGGCACAAAAACTACCATTCGCCTGATGAACTCTCAGCATGGTGACATGGACCAGAAGGAGAGAGATGTTATCATGAGGGA
ATTCCGGTCAGGGTCAAGTCGTGTTCTGATCACTACTGACTTGTTGGCTCGCGGGATTGATGTGCAACAAGTGTCTTTGGTTATAAATTA
TGATCTACCTACCAATCGTGAAAACTATATTCACAGAATTGGCAGAGGGGGTCGATTTGGGAGGAAAGGTGTGGCTATAAACTTTGTTAC
TGAAGAAGACAAGAGGATTCTTCGTGACATTGAGACTTTCTACAATACTACAGTGGAGGAGATGCCCATGAATGTGGCTGACCTTATTTA
ATTCCTGGGATGAGAGTTTTGGATGCAGTGCTCGCTGTTGCTGAATAGGCGATCACAACGTGCATTGTGCTTCTTTCTTTGGGAATATTT
GAATCTTGTCTCAATGCTCATAACGGATCAGAAATACAGATTTTGATAGCAAAGCGACGTTAGTCGTGAGCTCTTGTGAGGAAAGTCATT
GGCTTTATCCTCTTTAGAGTTAGACTGTTGGGGTGGGTATAAAAGATGGGGTCTGTAAAATCTTTCTTTCTTAGAAATTTATTTCCTAGT
TCTGTAGAAATGGTTGTATTAGATGTTCTCTATCATTTAATAATATACTTGTGGACTAAAAGATATAAGTGCTGTATAAAATCAGCCAAT
TATGTTAAACTAGCATATCTGCCTTTATTGTGTTTGTCATTAGCCTGAGTAGAAAGGCCTTTAAAATTTTTTTAGAAAGCATTTGAATGC
ATTTTGTTTGGTATTGTATTTATTCAATAAAGTATTTAATTAGTGCTAAGTGTGAACTGGACCCTGTTGCTAAGCCCCAGCAAGCAATCC

>In-frame_ENST00000448044_ENST00000440191_TCGA-25-1312-01A_ST6GAL1_chr3_186769134_+_EIF4A2_chr3_186505284_length(amino acids)=355AA_start in transcript=283_stop in transcript=1350
MFSCSEQSDFPEHIFIMIHTNLKKKFSCCVLVFLLFAVICVWKEKKKGSYYDSFKLQTKEFQVLKSLGKLAMGSDSQSVSSSSTQDPHRG
RQTLGSLRGLAKAKPEASFQVWNKDSSSKNLIPRLQKIWKNYLSMNKYKVSYKGPGPGIKFSAEALRCHLRDHVNVSMVEVTDFPFNTSE
WEGYLPKESIRTKAGPWGRCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQHGDMDQKERDVIMREFRSG

--------------------------------------------------------------
>In-frame_ENST00000448044_ENST00000356531_TCGA-25-1312-01A_ST6GAL1_chr3_186769134_+_EIF4A2_chr3_186505284_length(transcript)=1976nt_BP=1036nt
AACTTTCTGATAGCTTAATAGGAGGAGGTTCCTGTAGGGCGGCACAACCAGGGAGGGCGTGGAAGCTCTGCATCCCTTCTCCCATACCTT
GCTCTACACATCTCTTCATCTGTATCCTCTGCAGCATCCTTGATGATAAACCAGTAAATATGAGTTTTGATCATCCTGAGAAAAATGGGC
CTTGGCCTGCAGACCCAATAAACCTTCCCTCCCATGGATAATAGTGCTAATTCCTGAGGACCTGAAGGGCCTGCCGCCCCTGGGGGATTA
GCCAGAAGCAGGCTTGTTTTCCTGCTCAGAACAAAGTGACTTCCCTGAACACATCTTCATTATGATTCACACCAACCTGAAGAAAAAGTT
CAGCTGCTGCGTCCTGGTCTTTCTTCTGTTTGCAGTCATCTGTGTGTGGAAGGAAAAGAAGAAAGGGAGTTACTATGATTCCTTTAAATT
GCAAACCAAGGAATTCCAGGTGTTAAAGAGTCTGGGGAAATTGGCCATGGGGTCTGATTCCCAGTCTGTATCCTCAAGCAGCACCCAGGA
CCCCCACAGGGGCCGCCAGACCCTCGGCAGTCTCAGAGGCCTAGCCAAGGCCAAACCAGAGGCCTCCTTCCAGGTGTGGAACAAGGACAG
CTCTTCCAAAAACCTTATCCCTAGGCTGCAAAAGATCTGGAAGAATTACCTAAGCATGAACAAGTACAAAGTGTCCTACAAGGGGCCAGG
ACCAGGCATCAAGTTCAGTGCAGAGGCCCTGCGCTGCCACCTCCGGGACCATGTGAATGTATCCATGGTAGAGGTCACAGATTTTCCCTT
CAATACCTCTGAATGGGAGGGTTATCTGCCCAAGGAGAGCATTAGGACCAAGGCTGGGCCTTGGGGCAGGTGTGCTGTTGTGTCGTCAGC
GGGATCTCTGAAGTCCTCCCAACTAGGCAGAGAAATCGATGATCATGACGCAGTCCTGAGGTTTAATGGGGCACCCACAGCCAACTTCCA
ACAAGATGTGGGCACAAAAACTACCATTCGCCTGATGAACTCTCAGCATGGTGACATGGACCAGAAGGAGAGAGATGTTATCATGAGGGA
ATTCCGGTCAGGGTCAAGTCGTGTTCTGATCACTACTGACTTGTTGGCTCGCGGGATTGATGTGCAACAAGTGTCTTTGGTTATAAATTA
TGATCTACCTACCAATCGTGAAAACTATATTCACAGAATTGGCAGAGGGGGTCGATTTGGGAGGAAAGGTGTGGCTATAAACTTTGTTAC
TGAAGAAGACAAGAGGATTCTTCGTGACATTGAGACTTTCTACAATACTACAGTGGAGGAGATGCCCATGAATGTGGCTGACCTTATTTA
ATTCCTGGGATGAGAGTTTTGGATGCAGTGCTCGCTGTTGCTGAATAGGCGATCACAACGTGCATTGTGCTTCTTTCTTTGGGAATATTT
GAATCTTGTCTCAATGCTCATAACGGATCAGAAATACAGATTTTGATAGCAAAGCGACGTTAGTCGTGAGCTCTTGTGAGGAAAGTCATT
GGCTTTATCCTCTTTAGAGTTAGACTGTTGGGGTGGGTATAAAAGATGGGGTCTGTAAAATCTTTCTTTCTTAGAAATTTATTTCCTAGT
TCTGTAGAAATGGTTGTATTAGATGTTCTCTATCATTTAATAATATACTTGTGGACTAAAAGATATAAGTGCTGTATAAAATCAGCCAAT
TATGTTAAACTAGCATATCTGCCTTTATTGTGTTTGTCATTAGCCTGAGTAGAAAGGCCTTTAAAATTTTTTTAGAAAGCATTTGAATGC
ATTTTGTTTGGTATTGTATTTATTCAATAAAGTATTTAATTAGTGCTAAGTGTGAACTGGACCCTGTTGCTAAGCCCCAGCAAGCAATCC

>In-frame_ENST00000448044_ENST00000356531_TCGA-25-1312-01A_ST6GAL1_chr3_186769134_+_EIF4A2_chr3_186505284_length(amino acids)=355AA_start in transcript=283_stop in transcript=1350
MFSCSEQSDFPEHIFIMIHTNLKKKFSCCVLVFLLFAVICVWKEKKKGSYYDSFKLQTKEFQVLKSLGKLAMGSDSQSVSSSSTQDPHRG
RQTLGSLRGLAKAKPEASFQVWNKDSSSKNLIPRLQKIWKNYLSMNKYKVSYKGPGPGIKFSAEALRCHLRDHVNVSMVEVTDFPFNTSE
WEGYLPKESIRTKAGPWGRCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQHGDMDQKERDVIMREFRSG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ST6GAL1-EIF4A2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ST6GAL1-EIF4A2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ST6GAL1-EIF4A2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneST6GAL1C0001969Alcoholic Intoxication1PSYGENET
HgeneST6GAL1C0011860Diabetes Mellitus, Non-Insulin-Dependent1CTD_human
HgeneST6GAL1C0162820Dermatitis, Allergic Contact1CTD_human
HgeneST6GAL1C0337677Moderate drinker1PSYGENET
TgeneEIF4A2C0001969Alcoholic Intoxication1PSYGENET
TgeneEIF4A2C0027627Neoplasm Metastasis1CTD_human
TgeneEIF4A2C0394996Acute alcoholic intoxication1PSYGENET