Home

Download

Statistics

Examples

Help

Contact

	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:STARD10-CPT1A (FusionGDB2 ID:86549)

Fusion Gene Summary for STARD10-CPT1A

Fusion gene summary

Fusion gene information	Fusion gene name: STARD10-CPT1A
	Fusion gene ID: 86549
		Hgene	Tgene
	Gene symbol	STARD10	CPT1A
	Gene ID	10809	1374
	Gene name	StAR related lipid transfer domain containing 10	carnitine palmitoyltransferase 1A
	Synonyms	CGI-52\|NY-CO-28\|PCTP2\|SDCCAG28	CPT1\|CPT1-L\|L-CPT1
	Cytomap	11q13.4	11q13.3
	Type of gene	protein-coding	protein-coding
	Description	START domain-containing protein 10PCTP-LPCTP-like proteinSTART domain containing 10StAR-related lipid transfer (START) domain containing 10antigen NY-CO-28serologically defined colon cancer antigen 28stAR-related lipid transfer protein 10	carnitine O-palmitoyltransferase 1, liver isoformCPT ICPTI-Lcarnitine O-palmitoyltransferase I, liver isoformcarnitine palmitoyltransferase 1A (liver)carnitine palmitoyltransferase I, liver
	Modification date	20200313	20200315
	UniProtAcc	.	P50416
	Ensembl transtripts involved in fusion gene	ENST00000543304, ENST00000334805, ENST00000538536, ENST00000538437, ENST00000545082,	ENST00000540367, ENST00000376618, ENST00000265641, ENST00000539743, ENST00000537756, ENST00000538994,
Fusion gene scores	* DoF score	10 X 7 X 6=420	12 X 9 X 8=864
	# samples	10	15
	** MAII score	log2(10/420*10)=-2.0703893278914 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(15/864*10)=-2.52606881166759 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: STARD10 [Title/Abstract] AND CPT1A [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	STARD10(72492019)-CPT1A(68562379), # samples:1
Anticipated loss of major functional domain due to fusion event.	STARD10-CPT1A seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF. STARD10-CPT1A seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	CPT1A	GO:0001676	long-chain fatty acid metabolic process	11350182
Tgene	CPT1A	GO:0009437	carnitine metabolic process	11350182

Fusion gene breakpoints across STARD10 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across CPT1A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	STAD	TCGA-BR-8362	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-

Top

Fusion Gene ORF analysis for STARD10-CPT1A

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
Frame-shift	ENST00000543304	ENST00000540367	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-
Frame-shift	ENST00000543304	ENST00000376618	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-
Frame-shift	ENST00000543304	ENST00000265641	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-
Frame-shift	ENST00000543304	ENST00000539743	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-
5CDS-intron	ENST00000543304	ENST00000537756	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-
5CDS-intron	ENST00000543304	ENST00000538994	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-
In-frame	ENST00000334805	ENST00000540367	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-
In-frame	ENST00000334805	ENST00000376618	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-
In-frame	ENST00000334805	ENST00000265641	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-
In-frame	ENST00000334805	ENST00000539743	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-
5CDS-intron	ENST00000334805	ENST00000537756	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-
5CDS-intron	ENST00000334805	ENST00000538994	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-
intron-3CDS	ENST00000538536	ENST00000540367	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-
intron-3CDS	ENST00000538536	ENST00000376618	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-
intron-3CDS	ENST00000538536	ENST00000265641	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-
intron-3CDS	ENST00000538536	ENST00000539743	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-
intron-intron	ENST00000538536	ENST00000537756	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-
intron-intron	ENST00000538536	ENST00000538994	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-
5UTR-3CDS	ENST00000538437	ENST00000540367	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-
5UTR-3CDS	ENST00000538437	ENST00000376618	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-
5UTR-3CDS	ENST00000538437	ENST00000265641	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-
5UTR-3CDS	ENST00000538437	ENST00000539743	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-
5UTR-intron	ENST00000538437	ENST00000537756	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-
5UTR-intron	ENST00000538437	ENST00000538994	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-
intron-3CDS	ENST00000545082	ENST00000540367	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-
intron-3CDS	ENST00000545082	ENST00000376618	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-
intron-3CDS	ENST00000545082	ENST00000265641	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-
intron-3CDS	ENST00000545082	ENST00000539743	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-
intron-intron	ENST00000545082	ENST00000537756	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-
intron-intron	ENST00000545082	ENST00000538994	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000334805	STARD10	chr11	72492019	-	ENST00000540367	CPT1A	chr11	68562379	-	2823	1127	776	2626	616
ENST00000334805	STARD10	chr11	72492019	-	ENST00000376618	CPT1A	chr11	68562379	-	2821	1127	776	2626	616
ENST00000334805	STARD10	chr11	72492019	-	ENST00000265641	CPT1A	chr11	68562379	-	5433	1127	776	2677	633
ENST00000334805	STARD10	chr11	72492019	-	ENST00000539743	CPT1A	chr11	68562379	-	2709	1127	776	2677	633

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000334805	ENST00000540367	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-	0.004028572	0.9959714
ENST00000334805	ENST00000376618	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-	0.004096705	0.9959033
ENST00000334805	ENST00000265641	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-	0.002047941	0.99795204
ENST00000334805	ENST00000539743	STARD10	chr11	72492019	-	CPT1A	chr11	68562379	-	0.004178687	0.99582136

Top

Fusion Genomic Features for STARD10-CPT1A

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for STARD10-CPT1A

Go to
FGviewer for the breakpoints of chr11:72492019-chr11:68562379
.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	CPT1A P50416
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.	FUNCTION: Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion (PubMed:9691089, PubMed:11350182, PubMed:14517221). Plays an important role in hepatic triglyceride metabolism (By similarity). {ECO:0000250\|UniProtKB:P32198, ECO:0000269\|PubMed:11350182, ECO:0000269\|PubMed:14517221, ECO:0000269\|PubMed:9691089}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

CPT1A

chr11:72492019

chr11:68562379

ENST00000265641

555_567

257.0

774.0

Region

Coenzyme A binding

Tgene

CPT1A

chr11:72492019

chr11:68562379

ENST00000376618

555_567

257.0

757.0

Region

Coenzyme A binding

Tgene

CPT1A

chr11:72492019

chr11:68562379

ENST00000539743

555_567

257.0

774.0

Region

Coenzyme A binding

Tgene

CPT1A

chr11:72492019

chr11:68562379

ENST00000540367

555_567

257.0

757.0

Region

Coenzyme A binding

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

STARD10

chr11:72492019

chr11:68562379

ENST00000334805

14_224

69.0

292.0

Domain

START

Hgene

STARD10

chr11:72492019

chr11:68562379

ENST00000543304

14_224

69.0

292.0

Domain

START

Tgene

CPT1A

chr11:72492019

chr11:68562379

ENST00000265641

123_773

257.0

774.0

Topological domain

Cytoplasmic

Tgene

CPT1A

chr11:72492019

chr11:68562379

ENST00000265641

2_47

257.0

774.0

Topological domain

Cytoplasmic

Tgene

CPT1A

chr11:72492019

chr11:68562379

ENST00000265641

74_102

257.0

774.0

Topological domain

Mitochondrial intermembrane

Tgene

CPT1A

chr11:72492019

chr11:68562379

ENST00000376618

123_773

257.0

757.0

Topological domain

Cytoplasmic

Tgene

CPT1A

chr11:72492019

chr11:68562379

ENST00000376618

2_47

257.0

757.0

Topological domain

Cytoplasmic

Tgene

CPT1A

chr11:72492019

chr11:68562379

ENST00000376618

74_102

257.0

757.0

Topological domain

Mitochondrial intermembrane

Tgene

CPT1A

chr11:72492019

chr11:68562379

ENST00000539743

123_773

257.0

774.0

Topological domain

Cytoplasmic

Tgene

CPT1A

chr11:72492019

chr11:68562379

ENST00000539743

2_47

257.0

774.0

Topological domain

Cytoplasmic

Tgene

CPT1A

chr11:72492019

chr11:68562379

ENST00000539743

74_102

257.0

774.0

Topological domain

Mitochondrial intermembrane

Tgene

CPT1A

chr11:72492019

chr11:68562379

ENST00000540367

123_773

257.0

757.0

Topological domain

Cytoplasmic

Tgene

CPT1A

chr11:72492019

chr11:68562379

ENST00000540367

2_47

257.0

757.0

Topological domain

Cytoplasmic

Tgene

CPT1A

chr11:72492019

chr11:68562379

ENST00000540367

74_102

257.0

757.0

Topological domain

Mitochondrial intermembrane

Tgene

CPT1A

chr11:72492019

chr11:68562379

ENST00000265641

103_122

257.0

774.0

Transmembrane

Helical

Tgene

CPT1A

chr11:72492019

chr11:68562379

ENST00000265641

48_73

257.0

774.0

Transmembrane

Helical

Tgene

CPT1A

chr11:72492019

chr11:68562379

ENST00000376618

103_122

257.0

757.0

Transmembrane

Helical

Tgene

CPT1A

chr11:72492019

chr11:68562379

ENST00000376618

48_73

257.0

757.0

Transmembrane

Helical

Tgene

CPT1A

chr11:72492019

chr11:68562379

ENST00000539743

103_122

257.0

774.0

Transmembrane

Helical

Tgene

CPT1A

chr11:72492019

chr11:68562379

ENST00000539743

48_73

257.0

774.0

Transmembrane

Helical

Tgene

CPT1A

chr11:72492019

chr11:68562379

ENST00000540367

103_122

257.0

757.0

Transmembrane

Helical

Tgene

CPT1A

chr11:72492019

chr11:68562379

ENST00000540367

48_73

257.0

757.0

Transmembrane

Helical

Top

Fusion Gene Sequence for STARD10-CPT1A

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>In-frame_ENST00000334805_ENST00000540367_TCGA-BR-8362_STARD10_chr11_72492019_-_CPT1A_chr11_68562379_length(transcript)=2823nt_BP=1127nt
ACGTGGGGGCGCCTGAGCGAAGATAACCGTAATAAATAGTAACCTAACGGTCCAGTCATCGTTCTGTGGTCCTTTCTTTTATGATTCACA
AGGAATGACCCTCTTCATCGCCTCTCCTAATTCAGTCCTCACAACAGTCCTTTTACAAATGGGACAACAGGTTAGAGGAAGTCAGGCAGA
TTTCCAGCATCATAGAGAGTAAAGGACCAGGGAAGGATCAGGATTCAAGGACTGCACCCAGGCTCTGCTTCCAGCTTGCTGTGTGACTTT
GGGTAATTTTGTTCCCTTAGGGAACTGAGCTTTCTCATTTGTAAATGCAAACAGGCTGTTGGGAGGATCAAATGAGATCCAGGGGTGAAA
ACAGCTTAGTTTACTTTCAGGAATTTACCCACGCGGTATATAAAGGCAAAATATTATTATAGTCAGGTGATTGTAGATTGAGGAACCCAT
TTCCTCATTCTGCAAATTGCAAACCTGAGGGCCCAAAGAGGGACAGGGGCTTGCCCCAGGTCTCAGCAGGCTGTGAGCAAGAGCTAAAGC
CTAATCCTCCTGCCTTTGGGCCTGGAGCCCTTCCTTGTACCCCAGGGGTCAGTGTCTTTGTTGGATACAGGCTTAGATTGACTGACTGTA
CCCTGAGAACCTAGGGGAGTCCCTGTTCCCAATTCTTCTCCTACCCCCACCTTGGCCTGATGGAGGAAGACCCTGCTGTGTTGAGATGAG
CACCAGAGCCAAGAAGCTGAGGAGGATCTGGAGAATTCTGGAGGAAGAGGAGAGTGTTGCTGGAGCTGTACAGACCCTGCTTCTCAGGTC
CCAGGAAGGTGGCGTCAGCATCTGCAGCCGCGTCGACGTTGTCGGAGCCTCCGCGGAGGACCCAGGAGAGCCGGACTAGGACCAGGGCCC
TGGGCCTCCCCACACTCCCCATGGAGAAGCTGGCGGCCTCTACAGAGCCCCAAGGGCCTCGGCCGGTCCTGGGCCGTGAGAGTGTCCAGG
TGCCCGATGACCAAGACTTTCGCAGCTTCCGGTCAGAGTGTGAGGCTGAGGTGGGCTGGAACCTGACCTATAGCAGGGCTGGGGTGTCTG
TCTGGGTGCAGGCTGTGGAGATGGATCGGACGCTGCACAAGATCAAGGATCTGCTGTATATCCTTCCAACTCACATTCAGGCAGCAAGAG
CCGGCAACGCCATCCATGCCATCCTGCTTTACAGGCGCAAACTGGACCGGGAGGAAATCAAACCAATTCGTCTTTTGGGATCCACGATTC
CACTCTGCTCCGCTCAGTGGGAGCGGATGTTTAATACTTCCCGGATCCCAGGAGAGGAGACAGACACCATCCAGCACATGAGAGACAGCA
AGCACATCGTCGTGTACCATCGAGGACGCTACTTCAAGGTCTGGCTCTACCATGATGGGCGGCTGCTGAAGCCCCGGGAGATGGAGCAGC
AGATGCAGAGGATCCTGGACAATACCTCGGAGCCTCAGCCCGGGGAGGCCAGGCTGGCAGCCCTCACCGCAGGAGACAGAGTTCCCTGGG
CCAGGTGTCGTCAGGCCTATTTTGGACGTGGGAAAAATAAGCAGTCTCTTGATGCTGTGGAGAAAGCAGCGTTCTTTGTGACGTTAGATG
AAACTGAAGAAGGATACAGAAGTGAAGACCCGGATACGTCAATGGACAGCTACGCCAAATCTCTACTACACGGCCGATGTTACGACAGGT
GGTTTGACAAGTCGTTCACGTTTGTTGTCTTCAAAAACGGGAAGATGGGCCTCAACGCTGAACACTCCTGGGCAGATGCGCCGATCGTGG
CCCACCTTTGGGAGTACGTCATGTCCATTGACAGCCTCCAGCTGGGCTATGCGGAGGATGGGCACTGCAAAGGCGACATCAATCCGAACA
TTCCGTACCCCACCAGGCTGCAGTGGGACATCCCGGGGGAATGTCAAGAGGTTATAGAGACCTCCCTGAACACCGCAAATCTTCTGGCAA
ACGACGTGGATTTCCATTCCTTCCCATTCGTAGCCTTTGGTAAAGGAATCATCAAGAAATGTCGCACGAGCCCAGACGCCTTTGTGCAGC
TGGCCCTCCAGCTGGCGCACTACAAGGACATGGGCAAGTTTTGCCTCACATACGAGGCCTCCATGACCCGGCTCTTCCGAGAGGGGAGGA
CGGAGACCGTGCGCTCCTGCACCACTGAGTCATGCGACTTCGTGCGGGCCATGGTGGACCCGGCCCAGACGGTGGAACAGAGGCTGAAGT
TGTTCAAGTTGGCGTCTGAGAAGCATCAGCATATGTATCGCCTCGCCATGACCGGCTCTGGGATCGATCGTCACCTCTTCTGCCTTTACG
TGGTGTCTAAATATCTCGCTGTGGAGTCCCCTTTCCTTAAGGAAGTTTTATCTGAGCCTTGGAGATTATCAACAAGCCAGACCCCTCAGC
AGCAAGTGGAGCTGTTTGACTTGGAGAATAACCCAGAGTACGTGTCCAGCGGAGGGGGCTTTGGACCGGTTGCTGATGACGGCTATGGTG
TGTCGTACATCCTTGTGGGAGAGAACCTCATCAATTTCCACATTTCTTCCAAGTTCTCTTGCCCTGAGACGGGGATTATAAGTCAAGGAC
CAAGTTCAGATACTTGAGACAAAGTGGAAAGTCTCAGCATATGGAAACAAGGCCTTGGAGGAGACCATGGACATCACCAAGTTCATGTGC
TGGGCTGGAAAGAAAAGCCTGTTGATTTTCACTTGCTGTGCATTTATTCATCCATTCCATTGCCTCAATGCTGAGAACAGTGCCTGACAC

>In-frame_ENST00000334805_ENST00000540367_TCGA-BR-8362_STARD10_chr11_72492019_-_CPT1A_chr11_68562379_length(amino acids)=616AA_start in transcript=776_stop in transcript=2626
MLELYRPCFSGPRKVASASAAASTLSEPPRRTQESRTRTRALGLPTLPMEKLAASTEPQGPRPVLGRESVQVPDDQDFRSFRSECEAEVG
WNLTYSRAGVSVWVQAVEMDRTLHKIKDLLYILPTHIQAARAGNAIHAILLYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGE
ETDTIQHMRDSKHIVVYHRGRYFKVWLYHDGRLLKPREMEQQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDA
VEKAAFFVTLDETEEGYRSEDPDTSMDSYAKSLLHGRCYDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQLGYAE
DGHCKGDINPNIPYPTRLQWDIPGECQEVIETSLNTANLLANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKDMGKFCLTYE
ASMTRLFREGRTETVRSCTTESCDFVRAMVDPAQTVEQRLKLFKLASEKHQHMYRLAMTGSGIDRHLFCLYVVSKYLAVESPFLKEVLSE

--------------------------------------------------------------
>In-frame_ENST00000334805_ENST00000376618_TCGA-BR-8362_STARD10_chr11_72492019_-_CPT1A_chr11_68562379_length(transcript)=2821nt_BP=1127nt
ACGTGGGGGCGCCTGAGCGAAGATAACCGTAATAAATAGTAACCTAACGGTCCAGTCATCGTTCTGTGGTCCTTTCTTTTATGATTCACA
AGGAATGACCCTCTTCATCGCCTCTCCTAATTCAGTCCTCACAACAGTCCTTTTACAAATGGGACAACAGGTTAGAGGAAGTCAGGCAGA
TTTCCAGCATCATAGAGAGTAAAGGACCAGGGAAGGATCAGGATTCAAGGACTGCACCCAGGCTCTGCTTCCAGCTTGCTGTGTGACTTT
GGGTAATTTTGTTCCCTTAGGGAACTGAGCTTTCTCATTTGTAAATGCAAACAGGCTGTTGGGAGGATCAAATGAGATCCAGGGGTGAAA
ACAGCTTAGTTTACTTTCAGGAATTTACCCACGCGGTATATAAAGGCAAAATATTATTATAGTCAGGTGATTGTAGATTGAGGAACCCAT
TTCCTCATTCTGCAAATTGCAAACCTGAGGGCCCAAAGAGGGACAGGGGCTTGCCCCAGGTCTCAGCAGGCTGTGAGCAAGAGCTAAAGC
CTAATCCTCCTGCCTTTGGGCCTGGAGCCCTTCCTTGTACCCCAGGGGTCAGTGTCTTTGTTGGATACAGGCTTAGATTGACTGACTGTA
CCCTGAGAACCTAGGGGAGTCCCTGTTCCCAATTCTTCTCCTACCCCCACCTTGGCCTGATGGAGGAAGACCCTGCTGTGTTGAGATGAG
CACCAGAGCCAAGAAGCTGAGGAGGATCTGGAGAATTCTGGAGGAAGAGGAGAGTGTTGCTGGAGCTGTACAGACCCTGCTTCTCAGGTC
CCAGGAAGGTGGCGTCAGCATCTGCAGCCGCGTCGACGTTGTCGGAGCCTCCGCGGAGGACCCAGGAGAGCCGGACTAGGACCAGGGCCC
TGGGCCTCCCCACACTCCCCATGGAGAAGCTGGCGGCCTCTACAGAGCCCCAAGGGCCTCGGCCGGTCCTGGGCCGTGAGAGTGTCCAGG
TGCCCGATGACCAAGACTTTCGCAGCTTCCGGTCAGAGTGTGAGGCTGAGGTGGGCTGGAACCTGACCTATAGCAGGGCTGGGGTGTCTG
TCTGGGTGCAGGCTGTGGAGATGGATCGGACGCTGCACAAGATCAAGGATCTGCTGTATATCCTTCCAACTCACATTCAGGCAGCAAGAG
CCGGCAACGCCATCCATGCCATCCTGCTTTACAGGCGCAAACTGGACCGGGAGGAAATCAAACCAATTCGTCTTTTGGGATCCACGATTC
CACTCTGCTCCGCTCAGTGGGAGCGGATGTTTAATACTTCCCGGATCCCAGGAGAGGAGACAGACACCATCCAGCACATGAGAGACAGCA
AGCACATCGTCGTGTACCATCGAGGACGCTACTTCAAGGTCTGGCTCTACCATGATGGGCGGCTGCTGAAGCCCCGGGAGATGGAGCAGC
AGATGCAGAGGATCCTGGACAATACCTCGGAGCCTCAGCCCGGGGAGGCCAGGCTGGCAGCCCTCACCGCAGGAGACAGAGTTCCCTGGG
CCAGGTGTCGTCAGGCCTATTTTGGACGTGGGAAAAATAAGCAGTCTCTTGATGCTGTGGAGAAAGCAGCGTTCTTTGTGACGTTAGATG
AAACTGAAGAAGGATACAGAAGTGAAGACCCGGATACGTCAATGGACAGCTACGCCAAATCTCTACTACACGGCCGATGTTACGACAGGT
GGTTTGACAAGTCGTTCACGTTTGTTGTCTTCAAAAACGGGAAGATGGGCCTCAACGCTGAACACTCCTGGGCAGATGCGCCGATCGTGG
CCCACCTTTGGGAGTACGTCATGTCCATTGACAGCCTCCAGCTGGGCTATGCGGAGGATGGGCACTGCAAAGGCGACATCAATCCGAACA
TTCCGTACCCCACCAGGCTGCAGTGGGACATCCCGGGGGAATGTCAAGAGGTTATAGAGACCTCCCTGAACACCGCAAATCTTCTGGCAA
ACGACGTGGATTTCCATTCCTTCCCATTCGTAGCCTTTGGTAAAGGAATCATCAAGAAATGTCGCACGAGCCCAGACGCCTTTGTGCAGC
TGGCCCTCCAGCTGGCGCACTACAAGGACATGGGCAAGTTTTGCCTCACATACGAGGCCTCCATGACCCGGCTCTTCCGAGAGGGGAGGA
CGGAGACCGTGCGCTCCTGCACCACTGAGTCATGCGACTTCGTGCGGGCCATGGTGGACCCGGCCCAGACGGTGGAACAGAGGCTGAAGT
TGTTCAAGTTGGCGTCTGAGAAGCATCAGCATATGTATCGCCTCGCCATGACCGGCTCTGGGATCGATCGTCACCTCTTCTGCCTTTACG
TGGTGTCTAAATATCTCGCTGTGGAGTCCCCTTTCCTTAAGGAAGTTTTATCTGAGCCTTGGAGATTATCAACAAGCCAGACCCCTCAGC
AGCAAGTGGAGCTGTTTGACTTGGAGAATAACCCAGAGTACGTGTCCAGCGGAGGGGGCTTTGGACCGGTTGCTGATGACGGCTATGGTG
TGTCGTACATCCTTGTGGGAGAGAACCTCATCAATTTCCACATTTCTTCCAAGTTCTCTTGCCCTGAGACGGGGATTATAAGTCAAGGAC
CAAGTTCAGATACTTGAGACAAAGTGGAAAGTCTCAGCATATGGAAACAAGGCCTTGGAGGAGACCATGGACATCACCAAGTTCATGTGC
TGGGCTGGAAAGAAAAGCCTGTTGATTTTCACTTGCTGTGCATTTATTCATCCATTCCATTGCCTCAATGCTGAGAACAGTGCCTGACAC

>In-frame_ENST00000334805_ENST00000376618_TCGA-BR-8362_STARD10_chr11_72492019_-_CPT1A_chr11_68562379_length(amino acids)=616AA_start in transcript=776_stop in transcript=2626
MLELYRPCFSGPRKVASASAAASTLSEPPRRTQESRTRTRALGLPTLPMEKLAASTEPQGPRPVLGRESVQVPDDQDFRSFRSECEAEVG
WNLTYSRAGVSVWVQAVEMDRTLHKIKDLLYILPTHIQAARAGNAIHAILLYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGE
ETDTIQHMRDSKHIVVYHRGRYFKVWLYHDGRLLKPREMEQQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDA
VEKAAFFVTLDETEEGYRSEDPDTSMDSYAKSLLHGRCYDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQLGYAE
DGHCKGDINPNIPYPTRLQWDIPGECQEVIETSLNTANLLANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKDMGKFCLTYE
ASMTRLFREGRTETVRSCTTESCDFVRAMVDPAQTVEQRLKLFKLASEKHQHMYRLAMTGSGIDRHLFCLYVVSKYLAVESPFLKEVLSE

--------------------------------------------------------------
>In-frame_ENST00000334805_ENST00000265641_TCGA-BR-8362_STARD10_chr11_72492019_-_CPT1A_chr11_68562379_length(transcript)=5433nt_BP=1127nt
ACGTGGGGGCGCCTGAGCGAAGATAACCGTAATAAATAGTAACCTAACGGTCCAGTCATCGTTCTGTGGTCCTTTCTTTTATGATTCACA
AGGAATGACCCTCTTCATCGCCTCTCCTAATTCAGTCCTCACAACAGTCCTTTTACAAATGGGACAACAGGTTAGAGGAAGTCAGGCAGA
TTTCCAGCATCATAGAGAGTAAAGGACCAGGGAAGGATCAGGATTCAAGGACTGCACCCAGGCTCTGCTTCCAGCTTGCTGTGTGACTTT
GGGTAATTTTGTTCCCTTAGGGAACTGAGCTTTCTCATTTGTAAATGCAAACAGGCTGTTGGGAGGATCAAATGAGATCCAGGGGTGAAA
ACAGCTTAGTTTACTTTCAGGAATTTACCCACGCGGTATATAAAGGCAAAATATTATTATAGTCAGGTGATTGTAGATTGAGGAACCCAT
TTCCTCATTCTGCAAATTGCAAACCTGAGGGCCCAAAGAGGGACAGGGGCTTGCCCCAGGTCTCAGCAGGCTGTGAGCAAGAGCTAAAGC
CTAATCCTCCTGCCTTTGGGCCTGGAGCCCTTCCTTGTACCCCAGGGGTCAGTGTCTTTGTTGGATACAGGCTTAGATTGACTGACTGTA
CCCTGAGAACCTAGGGGAGTCCCTGTTCCCAATTCTTCTCCTACCCCCACCTTGGCCTGATGGAGGAAGACCCTGCTGTGTTGAGATGAG
CACCAGAGCCAAGAAGCTGAGGAGGATCTGGAGAATTCTGGAGGAAGAGGAGAGTGTTGCTGGAGCTGTACAGACCCTGCTTCTCAGGTC
CCAGGAAGGTGGCGTCAGCATCTGCAGCCGCGTCGACGTTGTCGGAGCCTCCGCGGAGGACCCAGGAGAGCCGGACTAGGACCAGGGCCC
TGGGCCTCCCCACACTCCCCATGGAGAAGCTGGCGGCCTCTACAGAGCCCCAAGGGCCTCGGCCGGTCCTGGGCCGTGAGAGTGTCCAGG
TGCCCGATGACCAAGACTTTCGCAGCTTCCGGTCAGAGTGTGAGGCTGAGGTGGGCTGGAACCTGACCTATAGCAGGGCTGGGGTGTCTG
TCTGGGTGCAGGCTGTGGAGATGGATCGGACGCTGCACAAGATCAAGGATCTGCTGTATATCCTTCCAACTCACATTCAGGCAGCAAGAG
CCGGCAACGCCATCCATGCCATCCTGCTTTACAGGCGCAAACTGGACCGGGAGGAAATCAAACCAATTCGTCTTTTGGGATCCACGATTC
CACTCTGCTCCGCTCAGTGGGAGCGGATGTTTAATACTTCCCGGATCCCAGGAGAGGAGACAGACACCATCCAGCACATGAGAGACAGCA
AGCACATCGTCGTGTACCATCGAGGACGCTACTTCAAGGTCTGGCTCTACCATGATGGGCGGCTGCTGAAGCCCCGGGAGATGGAGCAGC
AGATGCAGAGGATCCTGGACAATACCTCGGAGCCTCAGCCCGGGGAGGCCAGGCTGGCAGCCCTCACCGCAGGAGACAGAGTTCCCTGGG
CCAGGTGTCGTCAGGCCTATTTTGGACGTGGGAAAAATAAGCAGTCTCTTGATGCTGTGGAGAAAGCAGCGTTCTTTGTGACGTTAGATG
AAACTGAAGAAGGATACAGAAGTGAAGACCCGGATACGTCAATGGACAGCTACGCCAAATCTCTACTACACGGCCGATGTTACGACAGGT
GGTTTGACAAGTCGTTCACGTTTGTTGTCTTCAAAAACGGGAAGATGGGCCTCAACGCTGAACACTCCTGGGCAGATGCGCCGATCGTGG
CCCACCTTTGGGAGTACGTCATGTCCATTGACAGCCTCCAGCTGGGCTATGCGGAGGATGGGCACTGCAAAGGCGACATCAATCCGAACA
TTCCGTACCCCACCAGGCTGCAGTGGGACATCCCGGGGGAATGTCAAGAGGTTATAGAGACCTCCCTGAACACCGCAAATCTTCTGGCAA
ACGACGTGGATTTCCATTCCTTCCCATTCGTAGCCTTTGGTAAAGGAATCATCAAGAAATGTCGCACGAGCCCAGACGCCTTTGTGCAGC
TGGCCCTCCAGCTGGCGCACTACAAGGACATGGGCAAGTTTTGCCTCACATACGAGGCCTCCATGACCCGGCTCTTCCGAGAGGGGAGGA
CGGAGACCGTGCGCTCCTGCACCACTGAGTCATGCGACTTCGTGCGGGCCATGGTGGACCCGGCCCAGACGGTGGAACAGAGGCTGAAGT
TGTTCAAGTTGGCGTCTGAGAAGCATCAGCATATGTATCGCCTCGCCATGACCGGCTCTGGGATCGATCGTCACCTCTTCTGCCTTTACG
TGGTGTCTAAATATCTCGCTGTGGAGTCCCCTTTCCTTAAGGAAGTTTTATCTGAGCCTTGGAGATTATCAACAAGCCAGACCCCTCAGC
AGCAAGTGGAGCTGTTTGACTTGGAGAATAACCCAGAGTACGTGTCCAGCGGAGGGGGCTTTGGACCGGTTGCTGATGACGGCTATGGTG
TGTCGTACATCCTTGTGGGAGAGAACCTCATCAATTTCCACATTTCTTCCAAGTTCTCTTGCCCTGAGACGGATTCTCATCGCTTTGGAA
GGCACCTGAAAGAAGCAATGACTGACATCATCACTTTGTTTGGTCTCAGTTCTAATTCCAAAAAGTAATTCCACTGGAGCTGCTGGGAAG
GAAAACGAGCTCTTCTGATGCAAACCAAATGAAAAATAGGCATTAATCCTGACCTTAGCTCGGGATGAAACACTGCTCTTAAAAAAACTC
AGTTTTCCTTCCAGAAAATGTGGGTGTTTTTTTTTCCTAGAACAGTATCTCTCCCCTGTGAAGCATAACCCCACTACTTCCAGACTTGCC
CTCCCTTGGGGGACATCTGATAAAGTCTCCCCTGATGTCTCCGCATCGGCTTGGATTTATTAAGGGATGCAAATCTTGTTGAGTTAATGA
AGGAATTAGTAGGGTTGTGGCTTCACACACAGTGGAATGGAAATGGTGTGCTTTCTCAGTGGCAACCGAAGGCCTAGTGCTTAAGGGCAT
TTAGCATCATCCAAGCAGGGTAAACTTTTGTTTTGTTAAAAGAAAAATGTGTTATTCAAGTTGGTGTCCCCAGTTGTAGCTAACACATCT
GGAATGCACTAACCAAAATGCTGTGCTTTGGAGACCTGCTTTTGTCACCGTGGGTAACCGTTCCCGTCTGGTCCAGTAGCCTGTGTTTGC
CTCTCCACATTTGAAGCAAGCAGGATGCAAGGTCTTCAGTTTTACTGACCTTGTATGTCTTCAAGTCTTCACAACCCAGTGCCTTAAAAA
TGAAAGGCCCTAAATGTAAGGGAGATGGAGAGAAAGATTTATTTTGTAGAGTCTTTGGGTGGAATTGTGGGTATACTGTTCCCTTCACAA
TTGACTGAGTATGGATAACCGTACATAAGCATTTGCTACACCCCACCAGCCCCCTCCCCCTCAGAAACACCAGTTCCTTCCCAAGGGCAG
CTGTGCCAGACTCCCCTCCCGGGACTGCCTTCTTGTCATCATAAGCAACAAAAGAAATAACAGGCACATGTCATAAAAGGGGAGCAAGGG
CCGTGATGGTCAGATAATTCACTCAAGAATAAAACATGACACGTGCCTCAGGAGGATCTCTTTCCCAAAGTGACAGCAAGGAGGGCAGGG
CATCGGCCACCAAGCGGGGACTAGCAAGTGAGGAAGGGGAGGGCAGCCCACCGTGGTGAGGAGAGAGTGGCTCCACGACCCCAAGGGATG
GCCTTCTCCTCCCACCCGGTGAGGGGAAAGACTCACCAGAGGGTGATGGAGACAGTATGCCGGCTCACCTTGGTGACCAGCCAAGATGTC
TCAAGTGACAGTGCTAGGTGTTCACCCAGCCTGTCCTTCAGATAGGAGTGCCTTCACGAAAGCGTCTCATGGACCACAAAGCAATTATGC
ACTGAGTCATCTTCAGTATTTAATGCAAAAATGAAGCATCATGGAATGAAATTCCCACTGTCTGTCATGACAAGCTTAGCTGTCCATTGT
TTTAAATTGTGTATTTATTTTTTTGACCACTTGGTTCTAGTTGGGCCTGACTCCTTCAGAGTGCTGCACCCCGATAGTACAACAGCGATG
GCTGAACTGTTGGAGTCGATGGAAGGTGCTTGCCGGAGAACACGTGCCTTTTTTTTTTTTTTTTTTTTTGAGATGGAGTTTCACTCTTGT
TGCCCAGGCTGGAGTGCAGTGGTGCAATCTCGGCTCACTGCAGCATCTGCCTTGCAGGTTCAAGCGATTCTCCTGTCTCAGCCTCCCAAG
TAGCTGGGATTACACGCCCAACACCATGCCCTGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCATCATATTGGTCAGGCTGGTCTC
GAACTCCTGACCTCAGGTGATCCACCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCATGCGCGGCCCACATGCATG
TTTTATGTATGTATACTTCATGATGTAAAAATCCCACCTTTATGGGCCAAAGATTTTTTTTCTCCTGAAAGCAAGAAAAAATGAAAACAA
AAGACAAAAAAAAAAAAAAAAGCGTCCAGGCGCGGTGGCTCATGCGTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGCGGATCACGAG
GTCAGGAGATGGAGACCATCCTGGCTAACACGGTGAAACCCCGTCTCTACTAAAAATTCAAAAAATGAGCCGGGCGTGGTGGCGGGCGCC
TGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAGGCGGAGCTTGCAGTGAGCCGAGATCGCTCCACTGCA
CTCCAGCCTGGGCGACAGAGCGAGACTCCGTCTAAAAAAAAAAGCAAAAACAAACCAACAACAAAAGCCCCTGACTGTCCGTCAAGCAGG
CAGCGGGGATGTAGCTCTCTCTGCCCTGGGCAAGAATAGCACTTCCCGTTAAAAGCCAGCAGCCGGCGTCAGTCCCTATCAGAGCCAGCT
AGATCATGCACTGTTGACCACTGAGCAATCTGTGTTACACTAGAGTTCACAGGGCATTTTGAGTGTAGACGTGAGTGCTTAAACATATTT
GGGTTTCTCTCTCAGGTTTTAAATGTTTCAAATGTAATTGTTGCTCATCAGTGCAGTTATCAATGCAATTTTATATTCCTTGAGGGGAGA
AAGAGGGGTCTTATTGTACATGTCCAAGGGGGGTGATAAGAGTATTATCTGTTTAATTTAATTGGAACAAACCATTGTCTTAACGCAGCC
ATGGTTTGAATTTGTTATCTTGGGCTGACCGGTGCATGTAAATACAGTATGCTCTTTGGATGTAAATCTTAGAAATGCAGTGTGAATGTA

>In-frame_ENST00000334805_ENST00000265641_TCGA-BR-8362_STARD10_chr11_72492019_-_CPT1A_chr11_68562379_length(amino acids)=633AA_start in transcript=776_stop in transcript=2677
MLELYRPCFSGPRKVASASAAASTLSEPPRRTQESRTRTRALGLPTLPMEKLAASTEPQGPRPVLGRESVQVPDDQDFRSFRSECEAEVG
WNLTYSRAGVSVWVQAVEMDRTLHKIKDLLYILPTHIQAARAGNAIHAILLYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGE
ETDTIQHMRDSKHIVVYHRGRYFKVWLYHDGRLLKPREMEQQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDA
VEKAAFFVTLDETEEGYRSEDPDTSMDSYAKSLLHGRCYDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQLGYAE
DGHCKGDINPNIPYPTRLQWDIPGECQEVIETSLNTANLLANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKDMGKFCLTYE
ASMTRLFREGRTETVRSCTTESCDFVRAMVDPAQTVEQRLKLFKLASEKHQHMYRLAMTGSGIDRHLFCLYVVSKYLAVESPFLKEVLSE
PWRLSTSQTPQQQVELFDLENNPEYVSSGGGFGPVADDGYGVSYILVGENLINFHISSKFSCPETDSHRFGRHLKEAMTDIITLFGLSSN

--------------------------------------------------------------
>In-frame_ENST00000334805_ENST00000539743_TCGA-BR-8362_STARD10_chr11_72492019_-_CPT1A_chr11_68562379_length(transcript)=2709nt_BP=1127nt
ACGTGGGGGCGCCTGAGCGAAGATAACCGTAATAAATAGTAACCTAACGGTCCAGTCATCGTTCTGTGGTCCTTTCTTTTATGATTCACA
AGGAATGACCCTCTTCATCGCCTCTCCTAATTCAGTCCTCACAACAGTCCTTTTACAAATGGGACAACAGGTTAGAGGAAGTCAGGCAGA
TTTCCAGCATCATAGAGAGTAAAGGACCAGGGAAGGATCAGGATTCAAGGACTGCACCCAGGCTCTGCTTCCAGCTTGCTGTGTGACTTT
GGGTAATTTTGTTCCCTTAGGGAACTGAGCTTTCTCATTTGTAAATGCAAACAGGCTGTTGGGAGGATCAAATGAGATCCAGGGGTGAAA
ACAGCTTAGTTTACTTTCAGGAATTTACCCACGCGGTATATAAAGGCAAAATATTATTATAGTCAGGTGATTGTAGATTGAGGAACCCAT
TTCCTCATTCTGCAAATTGCAAACCTGAGGGCCCAAAGAGGGACAGGGGCTTGCCCCAGGTCTCAGCAGGCTGTGAGCAAGAGCTAAAGC
CTAATCCTCCTGCCTTTGGGCCTGGAGCCCTTCCTTGTACCCCAGGGGTCAGTGTCTTTGTTGGATACAGGCTTAGATTGACTGACTGTA
CCCTGAGAACCTAGGGGAGTCCCTGTTCCCAATTCTTCTCCTACCCCCACCTTGGCCTGATGGAGGAAGACCCTGCTGTGTTGAGATGAG
CACCAGAGCCAAGAAGCTGAGGAGGATCTGGAGAATTCTGGAGGAAGAGGAGAGTGTTGCTGGAGCTGTACAGACCCTGCTTCTCAGGTC
CCAGGAAGGTGGCGTCAGCATCTGCAGCCGCGTCGACGTTGTCGGAGCCTCCGCGGAGGACCCAGGAGAGCCGGACTAGGACCAGGGCCC
TGGGCCTCCCCACACTCCCCATGGAGAAGCTGGCGGCCTCTACAGAGCCCCAAGGGCCTCGGCCGGTCCTGGGCCGTGAGAGTGTCCAGG
TGCCCGATGACCAAGACTTTCGCAGCTTCCGGTCAGAGTGTGAGGCTGAGGTGGGCTGGAACCTGACCTATAGCAGGGCTGGGGTGTCTG
TCTGGGTGCAGGCTGTGGAGATGGATCGGACGCTGCACAAGATCAAGGATCTGCTGTATATCCTTCCAACTCACATTCAGGCAGCAAGAG
CCGGCAACGCCATCCATGCCATCCTGCTTTACAGGCGCAAACTGGACCGGGAGGAAATCAAACCAATTCGTCTTTTGGGATCCACGATTC
CACTCTGCTCCGCTCAGTGGGAGCGGATGTTTAATACTTCCCGGATCCCAGGAGAGGAGACAGACACCATCCAGCACATGAGAGACAGCA
AGCACATCGTCGTGTACCATCGAGGACGCTACTTCAAGGTCTGGCTCTACCATGATGGGCGGCTGCTGAAGCCCCGGGAGATGGAGCAGC
AGATGCAGAGGATCCTGGACAATACCTCGGAGCCTCAGCCCGGGGAGGCCAGGCTGGCAGCCCTCACCGCAGGAGACAGAGTTCCCTGGG
CCAGGTGTCGTCAGGCCTATTTTGGACGTGGGAAAAATAAGCAGTCTCTTGATGCTGTGGAGAAAGCAGCGTTCTTTGTGACGTTAGATG
AAACTGAAGAAGGATACAGAAGTGAAGACCCGGATACGTCAATGGACAGCTACGCCAAATCTCTACTACACGGCCGATGTTACGACAGGT
GGTTTGACAAGTCGTTCACGTTTGTTGTCTTCAAAAACGGGAAGATGGGCCTCAACGCTGAACACTCCTGGGCAGATGCGCCGATCGTGG
CCCACCTTTGGGAGTACGTCATGTCCATTGACAGCCTCCAGCTGGGCTATGCGGAGGATGGGCACTGCAAAGGCGACATCAATCCGAACA
TTCCGTACCCCACCAGGCTGCAGTGGGACATCCCGGGGGAATGTCAAGAGGTTATAGAGACCTCCCTGAACACCGCAAATCTTCTGGCAA
ACGACGTGGATTTCCATTCCTTCCCATTCGTAGCCTTTGGTAAAGGAATCATCAAGAAATGTCGCACGAGCCCAGACGCCTTTGTGCAGC
TGGCCCTCCAGCTGGCGCACTACAAGGACATGGGCAAGTTTTGCCTCACATACGAGGCCTCCATGACCCGGCTCTTCCGAGAGGGGAGGA
CGGAGACCGTGCGCTCCTGCACCACTGAGTCATGCGACTTCGTGCGGGCCATGGTGGACCCGGCCCAGACGGTGGAACAGAGGCTGAAGT
TGTTCAAGTTGGCGTCTGAGAAGCATCAGCATATGTATCGCCTCGCCATGACCGGCTCTGGGATCGATCGTCACCTCTTCTGCCTTTACG
TGGTGTCTAAATATCTCGCTGTGGAGTCCCCTTTCCTTAAGGAAGTTTTATCTGAGCCTTGGAGATTATCAACAAGCCAGACCCCTCAGC
AGCAAGTGGAGCTGTTTGACTTGGAGAATAACCCAGAGTACGTGTCCAGCGGAGGGGGCTTTGGACCGGTTGCTGATGACGGCTATGGTG
TGTCGTACATCCTTGTGGGAGAGAACCTCATCAATTTCCACATTTCTTCCAAGTTCTCTTGCCCTGAGACGGATTCTCATCGCTTTGGAA
GGCACCTGAAAGAAGCAATGACTGACATCATCACTTTGTTTGGTCTCAGTTCTAATTCCAAAAAGTAATTCCACTGGAGCTGCTGGGAAG

>In-frame_ENST00000334805_ENST00000539743_TCGA-BR-8362_STARD10_chr11_72492019_-_CPT1A_chr11_68562379_length(amino acids)=633AA_start in transcript=776_stop in transcript=2677
MLELYRPCFSGPRKVASASAAASTLSEPPRRTQESRTRTRALGLPTLPMEKLAASTEPQGPRPVLGRESVQVPDDQDFRSFRSECEAEVG
WNLTYSRAGVSVWVQAVEMDRTLHKIKDLLYILPTHIQAARAGNAIHAILLYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGE
ETDTIQHMRDSKHIVVYHRGRYFKVWLYHDGRLLKPREMEQQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDA
VEKAAFFVTLDETEEGYRSEDPDTSMDSYAKSLLHGRCYDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQLGYAE
DGHCKGDINPNIPYPTRLQWDIPGECQEVIETSLNTANLLANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKDMGKFCLTYE
ASMTRLFREGRTETVRSCTTESCDFVRAMVDPAQTVEQRLKLFKLASEKHQHMYRLAMTGSGIDRHLFCLYVVSKYLAVESPFLKEVLSE
PWRLSTSQTPQQQVELFDLENNPEYVSSGGGFGPVADDGYGVSYILVGENLINFHISSKFSCPETDSHRFGRHLKEAMTDIITLFGLSSN

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for STARD10-CPT1A

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for STARD10-CPT1A

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner	Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
Tgene	CPT1A	P50416	DB01016	Glyburide	Inhibitor	Small molecule	Approved
Tgene	CPT1A	P50416	DB01016	Glyburide	Inhibitor	Small molecule	Approved
Tgene	CPT1A	P50416	DB00583	Levocarnitine	Activator	Small molecule	Approved\|Investigational
Tgene	CPT1A	P50416	DB00583	Levocarnitine	Activator	Small molecule	Approved\|Investigational
Tgene	CPT1A	P50416	DB01074	Perhexiline	Inhibitor	Small molecule	Approved\|Investigational
Tgene	CPT1A	P50416	DB01074	Perhexiline	Inhibitor	Small molecule	Approved\|Investigational

Top

Related Diseases for STARD10-CPT1A

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	STARD10	C0033578	Prostatic Neoplasms	1	CTD_human
Hgene	STARD10	C0376358	Malignant neoplasm of prostate	1	CTD_human
Tgene	CPT1A	C1829703	Carnitine palmitoyl transferase 1A deficiency	13	CLINGEN;CTD_human;GENOMICS_ENGLAND;UNIPROT
Tgene	CPT1A	C0002152	Alloxan Diabetes	1	CTD_human
Tgene	CPT1A	C0006142	Malignant neoplasm of breast	1	CTD_human
Tgene	CPT1A	C0011849	Diabetes Mellitus	1	CTD_human
Tgene	CPT1A	C0011853	Diabetes Mellitus, Experimental	1	CTD_human
Tgene	CPT1A	C0011860	Diabetes Mellitus, Non-Insulin-Dependent	1	CTD_human
Tgene	CPT1A	C0022661	Kidney Failure, Chronic	1	CTD_human
Tgene	CPT1A	C0038433	Streptozotocin Diabetes	1	CTD_human
Tgene	CPT1A	C0400966	Non-alcoholic Fatty Liver Disease	1	CTD_human
Tgene	CPT1A	C0678222	Breast Carcinoma	1	CTD_human
Tgene	CPT1A	C1257931	Mammary Neoplasms, Human	1	CTD_human
Tgene	CPT1A	C1458155	Mammary Neoplasms	1	CTD_human
Tgene	CPT1A	C3241937	Nonalcoholic Steatohepatitis	1	CTD_human
Tgene	CPT1A	C4704874	Mammary Carcinoma, Human	1	CTD_human