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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:STAT3-C1orf43 (FusionGDB2 ID:86637) |
Fusion Gene Summary for STAT3-C1orf43 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: STAT3-C1orf43 | Fusion gene ID: 86637 | Hgene | Tgene | Gene symbol | STAT3 | C1orf43 | Gene ID | 6774 | 25912 |
| Gene name | signal transducer and activator of transcription 3 | chromosome 1 open reading frame 43 | |
| Synonyms | ADMIO|ADMIO1|APRF|HIES | HSPC012|NICE-3|NICE3|NS5ATP4|S863-3 | |
| Cytomap | 17q21.2 | 1q21.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | signal transducer and activator of transcription 3DNA-binding protein APRFacute-phase response factor | uncharacterized protein C1orf43HCV NS5A-transactivated protein 4hepatitis C virus NS5A-transactivated protein 4 | |
| Modification date | 20200329 | 20200327 | |
| UniProtAcc | . | Q9BWL3 | |
| Ensembl transtripts involved in fusion gene | ENST00000264657, ENST00000585517, ENST00000389272, ENST00000588969, ENST00000404395, ENST00000590776, | ENST00000368521, ENST00000362076, ENST00000350592, ENST00000368519, ENST00000483282, ENST00000368518, ENST00000368516, | |
| Fusion gene scores | * DoF score | 18 X 20 X 10=3600 | 5 X 5 X 4=100 |
| # samples | 23 | 5 | |
| ** MAII score | log2(23/3600*10)=-3.96829114027266 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/100*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: STAT3 [Title/Abstract] AND C1orf43 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | STAT3(40497577)-C1orf43(154180124), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | STAT3-C1orf43 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF. STAT3-C1orf43 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF. STAT3-C1orf43 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF. STAT3-C1orf43 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF. STAT3-C1orf43 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | STAT3 | GO:0006355 | regulation of transcription, DNA-templated | 15664994|17344214 |
| Hgene | STAT3 | GO:0006606 | protein import into nucleus | 18234692 |
| Hgene | STAT3 | GO:0010507 | negative regulation of autophagy | 26962683 |
| Hgene | STAT3 | GO:0010628 | positive regulation of gene expression | 23820254 |
| Hgene | STAT3 | GO:0030522 | intracellular receptor signaling pathway | 17324931 |
| Hgene | STAT3 | GO:0032355 | response to estradiol | 12552091 |
| Hgene | STAT3 | GO:0032870 | cellular response to hormone stimulus | 12552091 |
| Hgene | STAT3 | GO:0033210 | leptin-mediated signaling pathway | 17344214 |
| Hgene | STAT3 | GO:0035278 | miRNA mediated inhibition of translation | 23820254 |
| Hgene | STAT3 | GO:0044320 | cellular response to leptin stimulus | 17344214 |
| Hgene | STAT3 | GO:0044321 | response to leptin | 17344214 |
| Hgene | STAT3 | GO:0045893 | positive regulation of transcription, DNA-templated | 19390056 |
| Hgene | STAT3 | GO:0045944 | positive regulation of transcription by RNA polymerase II | 17324931|27050391|31462771 |
| Hgene | STAT3 | GO:0051726 | regulation of cell cycle | 17344214 |
| Hgene | STAT3 | GO:0060396 | growth hormone receptor signaling pathway | 10925297 |
| Hgene | STAT3 | GO:0060397 | JAK-STAT cascade involved in growth hormone signaling pathway | 12552091 |
| Hgene | STAT3 | GO:0070102 | interleukin-6-mediated signaling pathway | 12359225|12552091|17324931|24429361 |
| Hgene | STAT3 | GO:1902895 | positive regulation of pri-miRNA transcription by RNA polymerase II | 19390056|23820254 |
| Hgene | STAT3 | GO:2000637 | positive regulation of gene silencing by miRNA | 23820254 |
| Fusion gene breakpoints across STAT3 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene breakpoints across C1orf43 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | LIHC | TCGA-G3-A7M7-01A | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| ChimerDB4 | LIHC | TCGA-G3-A7M7-01A | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
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Fusion Gene ORF analysis for STAT3-C1orf43 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000264657 | ENST00000368521 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| Frame-shift | ENST00000264657 | ENST00000362076 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| Frame-shift | ENST00000264657 | ENST00000350592 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| Frame-shift | ENST00000264657 | ENST00000368519 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| 5CDS-5UTR | ENST00000264657 | ENST00000483282 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| 5CDS-intron | ENST00000264657 | ENST00000368518 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| 5CDS-intron | ENST00000264657 | ENST00000368516 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| In-frame | ENST00000585517 | ENST00000368521 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| Frame-shift | ENST00000585517 | ENST00000362076 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| In-frame | ENST00000585517 | ENST00000350592 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| In-frame | ENST00000585517 | ENST00000368519 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| 5CDS-5UTR | ENST00000585517 | ENST00000483282 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| 5CDS-intron | ENST00000585517 | ENST00000368518 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| 5CDS-intron | ENST00000585517 | ENST00000368516 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| In-frame | ENST00000389272 | ENST00000368521 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| Frame-shift | ENST00000389272 | ENST00000362076 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| In-frame | ENST00000389272 | ENST00000350592 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| In-frame | ENST00000389272 | ENST00000368519 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| 5CDS-5UTR | ENST00000389272 | ENST00000483282 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| 5CDS-intron | ENST00000389272 | ENST00000368518 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| 5CDS-intron | ENST00000389272 | ENST00000368516 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| In-frame | ENST00000588969 | ENST00000368521 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| Frame-shift | ENST00000588969 | ENST00000362076 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| In-frame | ENST00000588969 | ENST00000350592 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| In-frame | ENST00000588969 | ENST00000368519 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| 5CDS-5UTR | ENST00000588969 | ENST00000483282 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| 5CDS-intron | ENST00000588969 | ENST00000368518 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| 5CDS-intron | ENST00000588969 | ENST00000368516 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| In-frame | ENST00000404395 | ENST00000368521 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| Frame-shift | ENST00000404395 | ENST00000362076 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| In-frame | ENST00000404395 | ENST00000350592 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| In-frame | ENST00000404395 | ENST00000368519 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| 5CDS-5UTR | ENST00000404395 | ENST00000483282 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| 5CDS-intron | ENST00000404395 | ENST00000368518 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| 5CDS-intron | ENST00000404395 | ENST00000368516 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| intron-3CDS | ENST00000590776 | ENST00000368521 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| intron-3CDS | ENST00000590776 | ENST00000362076 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| intron-3CDS | ENST00000590776 | ENST00000350592 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| intron-3CDS | ENST00000590776 | ENST00000368519 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| intron-5UTR | ENST00000590776 | ENST00000483282 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| intron-intron | ENST00000590776 | ENST00000368518 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| intron-intron | ENST00000590776 | ENST00000368516 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000585517 | STAT3 | chr17 | 40497577 | - | ENST00000368521 | C1orf43 | chr1 | 154180124 | - | 1480 | 537 | 193 | 732 | 179 |
| ENST00000585517 | STAT3 | chr17 | 40497577 | - | ENST00000350592 | C1orf43 | chr1 | 154180124 | - | 1466 | 537 | 193 | 732 | 179 |
| ENST00000585517 | STAT3 | chr17 | 40497577 | - | ENST00000368519 | C1orf43 | chr1 | 154180124 | - | 1010 | 537 | 193 | 732 | 179 |
| ENST00000389272 | STAT3 | chr17 | 40497577 | - | ENST00000368521 | C1orf43 | chr1 | 154180124 | - | 1340 | 397 | 158 | 592 | 144 |
| ENST00000389272 | STAT3 | chr17 | 40497577 | - | ENST00000350592 | C1orf43 | chr1 | 154180124 | - | 1326 | 397 | 158 | 592 | 144 |
| ENST00000389272 | STAT3 | chr17 | 40497577 | - | ENST00000368519 | C1orf43 | chr1 | 154180124 | - | 870 | 397 | 158 | 592 | 144 |
| ENST00000588969 | STAT3 | chr17 | 40497577 | - | ENST00000368521 | C1orf43 | chr1 | 154180124 | - | 1520 | 577 | 13 | 582 | 189 |
| ENST00000588969 | STAT3 | chr17 | 40497577 | - | ENST00000350592 | C1orf43 | chr1 | 154180124 | - | 1506 | 577 | 13 | 582 | 189 |
| ENST00000588969 | STAT3 | chr17 | 40497577 | - | ENST00000368519 | C1orf43 | chr1 | 154180124 | - | 1050 | 577 | 13 | 582 | 189 |
| ENST00000404395 | STAT3 | chr17 | 40497577 | - | ENST00000368521 | C1orf43 | chr1 | 154180124 | - | 1452 | 509 | 165 | 704 | 179 |
| ENST00000404395 | STAT3 | chr17 | 40497577 | - | ENST00000350592 | C1orf43 | chr1 | 154180124 | - | 1438 | 509 | 165 | 704 | 179 |
| ENST00000404395 | STAT3 | chr17 | 40497577 | - | ENST00000368519 | C1orf43 | chr1 | 154180124 | - | 982 | 509 | 165 | 704 | 179 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000585517 | ENST00000368521 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - | 0.30178827 | 0.6982118 |
| ENST00000585517 | ENST00000350592 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - | 0.3278077 | 0.67219234 |
| ENST00000585517 | ENST00000368519 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - | 0.11955846 | 0.8804416 |
| ENST00000389272 | ENST00000368521 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - | 0.23582916 | 0.7641708 |
| ENST00000389272 | ENST00000350592 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - | 0.2643285 | 0.73567146 |
| ENST00000389272 | ENST00000368519 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - | 0.0716236 | 0.92837644 |
| ENST00000588969 | ENST00000368521 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - | 0.23223081 | 0.7677692 |
| ENST00000588969 | ENST00000350592 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - | 0.2622374 | 0.7377626 |
| ENST00000588969 | ENST00000368519 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - | 0.12236421 | 0.8776358 |
| ENST00000404395 | ENST00000368521 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - | 0.31833568 | 0.68166435 |
| ENST00000404395 | ENST00000350592 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - | 0.3491597 | 0.65084034 |
| ENST00000404395 | ENST00000368519 | STAT3 | chr17 | 40497577 | - | C1orf43 | chr1 | 154180124 | - | 0.15380391 | 0.8461961 |
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Fusion Genomic Features for STAT3-C1orf43 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for STAT3-C1orf43 |
| Go to FGviewer for the breakpoints of chr17:40497577-chr1:154180124 - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | C1orf43 |
| FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes. | FUNCTION: General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages. {ECO:0000269|PubMed:31540829}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | C1orf43 | chr17:40497577 | chr1:154180124 | ENST00000368518 | 0 | 6 | 11_31 | 0 | 190.0 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | STAT3 | chr17:40497577 | chr1:154180124 | ENST00000264657 | - | 4 | 24 | 580_670 | 124.0 | 771.0 | Domain | SH2 |
| Hgene | STAT3 | chr17:40497577 | chr1:154180124 | ENST00000404395 | - | 4 | 24 | 580_670 | 124.0 | 770.0 | Domain | SH2 |
| Hgene | STAT3 | chr17:40497577 | chr1:154180124 | ENST00000588969 | - | 4 | 24 | 580_670 | 124.0 | 771.0 | Domain | SH2 |
| Hgene | STAT3 | chr17:40497577 | chr1:154180124 | ENST00000264657 | - | 4 | 24 | 150_162 | 124.0 | 771.0 | Motif | Note=Essential for nuclear import |
| Hgene | STAT3 | chr17:40497577 | chr1:154180124 | ENST00000404395 | - | 4 | 24 | 150_162 | 124.0 | 770.0 | Motif | Note=Essential for nuclear import |
| Hgene | STAT3 | chr17:40497577 | chr1:154180124 | ENST00000588969 | - | 4 | 24 | 150_162 | 124.0 | 771.0 | Motif | Note=Essential for nuclear import |
| Tgene | C1orf43 | chr17:40497577 | chr1:154180124 | ENST00000350592 | 4 | 6 | 11_31 | 154.66666666666666 | 220.0 | Transmembrane | Helical | |
| Tgene | C1orf43 | chr17:40497577 | chr1:154180124 | ENST00000362076 | 3 | 5 | 11_31 | 136.66666666666666 | 202.0 | Transmembrane | Helical | |
| Tgene | C1orf43 | chr17:40497577 | chr1:154180124 | ENST00000368521 | 5 | 7 | 11_31 | 188.66666666666666 | 254.0 | Transmembrane | Helical |
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Fusion Gene Sequence for STAT3-C1orf43 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >In-frame_ENST00000585517_ENST00000368521_TCGA-G3-A7M7-01A_STAT3_chr17_40497577_-_C1orf43_chr1_154180124_length(transcript)=1480nt_BP=537nt GCAGCCGAGGGAACAAGCCCCAACCGGATCCTGGACAGGCACCCCGGCTTGGCGCTGTCTCTCCCCCTCGGCTCGGAGAGGCCCTTCGGC CTGAGGGAGCCTCGCCGCCCGTCCCCGGCACACGCGCAGCCCCGGCCTCTCGGCCTCTGCCGGAGAAACAGCAGGATGGCCCAATGGAAT CAGCTACAGCAGCTTGACACACGGTACCTGGAGCAGCTCCATCAGCTCTACAGTGACAGCTTCCCAATGGAGCTGCGGCAGTTTCTGGCC CCTTGGATTGAGAGTCAAGATTGGGCATATGCGGCCAGCAAAGAATCACATGCCACTTTGGTGTTTCATAATCTCCTGGGAGAGATTGAC CAGCAGTATAGCCGCTTCCTGCAAGAGTCGAATGTTCTCTATCAGCACAATCTACGAAGAATCAAGCAGTTTCTTCAGAGCAGGTATCTT GAGAAGCCAATGGAGATTGCCCGGATTGTGGCCCGGTGCCTGTGGGAAGAATCACGCCTTCTACAGACTGCAGCCACTGCGGCCCAGGGT TAAAGCACGAATTGGGAGCTCTCAGCGACATCACCAGTCAGCAGCCAAAGACCTAACTCAGTCCCCTGAGGTCTCCCCAACAACCATCCA GGTGACATACCTCCCCTCCAGTCAGAAGAGTAAACGTGCCAAGCACTTCCTTGAATTGAAGAGCTTTAAGGATAACTATAACACATTGGA GAGTACTCTGTGACGGAGCTGAAGGACTCTTGCCGTAGATTAAGCCAGTCAGTTGCAATGTGCAAGACAGGCTGCTTGCCGGGCCGCCCT CGGAACATCTGGCCCAGCAGGCCCAGACTGTATCCATCCAAGTTCCCGTTGTATCCAGAGTTCTTAGAGCTTGTGTCTAAAGGGTAATTC CCCAACCCTTCCTTATGAGCATTTTTAGAACATTGGCTAAGACTATTTTCCCCCAGTAGCGCTTTTTTCTGGATTTGCATTCAGGTGTTA TTCTTAATGTTTCTGTCAAAGCTTCTTAAAAATCTTCACTTGGTTTCAGCCATAGTTCACCTTCCCTGTTCCAGGTTTATTTAATTCCAA AGGTGAGAGTTGGAGTGAGATGTCTTCCATATCTATACCTTTGTGCACAGTTGAATGGGAACTGTTTGGGTTTAGGGCATCTTAGAGTTG ATTGATGGAAAAAGCAGACAGGAACTGGTGGGAGGTCAAGTGGGGAAGTTGGTGAATGTGGAATAACTTACCTTTGTGCTCCACTTAAAC CAGATGTGTTGCAGCTTTCCTGACATGCAAGGATCTACTTTAATTCCACACTCTCATTAATAAATTGAATAAAAGGGAATGTTTTGGCAC CTGATATAATCTGCCAGGCTATGTGACAGTAGGAAGGAATGGTTTCCCCTAACAAGCCCAATGCACTGGTCTGACTTTATAAATTATTTA >In-frame_ENST00000585517_ENST00000368521_TCGA-G3-A7M7-01A_STAT3_chr17_40497577_-_C1orf43_chr1_154180124_length(amino acids)=179AA_start in transcript=193_stop in transcript=732 MTHGTWSSSISSTVTASQWSCGSFWPLGLRVKIGHMRPAKNHMPLWCFIISWERLTSSIAASCKSRMFSISTIYEESSSFFRAGILRSQW -------------------------------------------------------------- >In-frame_ENST00000585517_ENST00000350592_TCGA-G3-A7M7-01A_STAT3_chr17_40497577_-_C1orf43_chr1_154180124_length(transcript)=1466nt_BP=537nt GCAGCCGAGGGAACAAGCCCCAACCGGATCCTGGACAGGCACCCCGGCTTGGCGCTGTCTCTCCCCCTCGGCTCGGAGAGGCCCTTCGGC CTGAGGGAGCCTCGCCGCCCGTCCCCGGCACACGCGCAGCCCCGGCCTCTCGGCCTCTGCCGGAGAAACAGCAGGATGGCCCAATGGAAT CAGCTACAGCAGCTTGACACACGGTACCTGGAGCAGCTCCATCAGCTCTACAGTGACAGCTTCCCAATGGAGCTGCGGCAGTTTCTGGCC CCTTGGATTGAGAGTCAAGATTGGGCATATGCGGCCAGCAAAGAATCACATGCCACTTTGGTGTTTCATAATCTCCTGGGAGAGATTGAC CAGCAGTATAGCCGCTTCCTGCAAGAGTCGAATGTTCTCTATCAGCACAATCTACGAAGAATCAAGCAGTTTCTTCAGAGCAGGTATCTT GAGAAGCCAATGGAGATTGCCCGGATTGTGGCCCGGTGCCTGTGGGAAGAATCACGCCTTCTACAGACTGCAGCCACTGCGGCCCAGGGT TAAAGCACGAATTGGGAGCTCTCAGCGACATCACCAGTCAGCAGCCAAAGACCTAACTCAGTCCCCTGAGGTCTCCCCAACAACCATCCA GGTGACATACCTCCCCTCCAGTCAGAAGAGTAAACGTGCCAAGCACTTCCTTGAATTGAAGAGCTTTAAGGATAACTATAACACATTGGA GAGTACTCTGTGACGGAGCTGAAGGACTCTTGCCGTAGATTAAGCCAGTCAGTTGCAATGTGCAAGACAGGCTGCTTGCCGGGCCGCCCT CGGAACATCTGGCCCAGCAGGCCCAGACTGTATCCATCCAAGTTCCCGTTGTATCCAGAGTTCTTAGAGCTTGTGTCTAAAGGGTAATTC CCCAACCCTTCCTTATGAGCATTTTTAGAACATTGGCTAAGACTATTTTCCCCCAGTAGCGCTTTTTTCTGGATTTGCATTCAGGTGTTA TTCTTAATGTTTCTGTCAAAGCTTCTTAAAAATCTTCACTTGGTTTCAGCCATAGTTCACCTTCCCTGTTCCAGGTTTATTTAATTCCAA AGGTGAGAGTTGGAGTGAGATGTCTTCCATATCTATACCTTTGTGCACAGTTGAATGGGAACTGTTTGGGTTTAGGGCATCTTAGAGTTG ATTGATGGAAAAAGCAGACAGGAACTGGTGGGAGGTCAAGTGGGGAAGTTGGTGAATGTGGAATAACTTACCTTTGTGCTCCACTTAAAC CAGATGTGTTGCAGCTTTCCTGACATGCAAGGATCTACTTTAATTCCACACTCTCATTAATAAATTGAATAAAAGGGAATGTTTTGGCAC CTGATATAATCTGCCAGGCTATGTGACAGTAGGAAGGAATGGTTTCCCCTAACAAGCCCAATGCACTGGTCTGACTTTATAAATTATTTA >In-frame_ENST00000585517_ENST00000350592_TCGA-G3-A7M7-01A_STAT3_chr17_40497577_-_C1orf43_chr1_154180124_length(amino acids)=179AA_start in transcript=193_stop in transcript=732 MTHGTWSSSISSTVTASQWSCGSFWPLGLRVKIGHMRPAKNHMPLWCFIISWERLTSSIAASCKSRMFSISTIYEESSSFFRAGILRSQW -------------------------------------------------------------- >In-frame_ENST00000585517_ENST00000368519_TCGA-G3-A7M7-01A_STAT3_chr17_40497577_-_C1orf43_chr1_154180124_length(transcript)=1010nt_BP=537nt GCAGCCGAGGGAACAAGCCCCAACCGGATCCTGGACAGGCACCCCGGCTTGGCGCTGTCTCTCCCCCTCGGCTCGGAGAGGCCCTTCGGC CTGAGGGAGCCTCGCCGCCCGTCCCCGGCACACGCGCAGCCCCGGCCTCTCGGCCTCTGCCGGAGAAACAGCAGGATGGCCCAATGGAAT CAGCTACAGCAGCTTGACACACGGTACCTGGAGCAGCTCCATCAGCTCTACAGTGACAGCTTCCCAATGGAGCTGCGGCAGTTTCTGGCC CCTTGGATTGAGAGTCAAGATTGGGCATATGCGGCCAGCAAAGAATCACATGCCACTTTGGTGTTTCATAATCTCCTGGGAGAGATTGAC CAGCAGTATAGCCGCTTCCTGCAAGAGTCGAATGTTCTCTATCAGCACAATCTACGAAGAATCAAGCAGTTTCTTCAGAGCAGGTATCTT GAGAAGCCAATGGAGATTGCCCGGATTGTGGCCCGGTGCCTGTGGGAAGAATCACGCCTTCTACAGACTGCAGCCACTGCGGCCCAGGGT TAAAGCACGAATTGGGAGCTCTCAGCGACATCACCAGTCAGCAGCCAAAGACCTAACTCAGTCCCCTGAGGTCTCCCCAACAACCATCCA GGTGACATACCTCCCCTCCAGTCAGAAGAGTAAACGTGCCAAGCACTTCCTTGAATTGAAGAGCTTTAAGGATAACTATAACACATTGGA GAGTACTCTGTGACGGAGCTGAAGGACTCTTGCCGTAGATTAAGCCAGTCAGTTGCAATGTGCAAGACAGGCTGCTTGCCGGGCCGCCCT CGGAACATCTGGCCCAGCAGGCCCAGACTGTATCCATCCAAGTTCCCGTTGTATCCAGAGTTCTTAGAGCTTGTGTCTAAAGGGTAATTC CCCAACCCTTCCTTATGAGCATTTTTAGAACATTGGCTAAGACTATTTTCCCCCAGTAGCGCTTTTTTCTGGATTTGCATTCAGGTGTTA >In-frame_ENST00000585517_ENST00000368519_TCGA-G3-A7M7-01A_STAT3_chr17_40497577_-_C1orf43_chr1_154180124_length(amino acids)=179AA_start in transcript=193_stop in transcript=732 MTHGTWSSSISSTVTASQWSCGSFWPLGLRVKIGHMRPAKNHMPLWCFIISWERLTSSIAASCKSRMFSISTIYEESSSFFRAGILRSQW -------------------------------------------------------------- >In-frame_ENST00000389272_ENST00000368521_TCGA-G3-A7M7-01A_STAT3_chr17_40497577_-_C1orf43_chr1_154180124_length(transcript)=1340nt_BP=397nt GGGAACAAGCCCCAACCGGATCCTGGACAGGCACCCCGGCTTGGCGCTGTCTCTCCCCCTCGGCTCGGAGAGGCCCTTCGGCCTGAGGGA GCCTCGCCGCCCGTCCCCGGCACACGCGCAGCCCCGGCCTCTCGGCCTCTGCCGGAGAAACAGGGCATATGCGGCCAGCAAAGAATCACA TGCCACTTTGGTGTTTCATAATCTCCTGGGAGAGATTGACCAGCAGTATAGCCGCTTCCTGCAAGAGTCGAATGTTCTCTATCAGCACAA TCTACGAAGAATCAAGCAGTTTCTTCAGAGCAGGTATCTTGAGAAGCCAATGGAGATTGCCCGGATTGTGGCCCGGTGCCTGTGGGAAGA ATCACGCCTTCTACAGACTGCAGCCACTGCGGCCCAGGGTTAAAGCACGAATTGGGAGCTCTCAGCGACATCACCAGTCAGCAGCCAAAG ACCTAACTCAGTCCCCTGAGGTCTCCCCAACAACCATCCAGGTGACATACCTCCCCTCCAGTCAGAAGAGTAAACGTGCCAAGCACTTCC TTGAATTGAAGAGCTTTAAGGATAACTATAACACATTGGAGAGTACTCTGTGACGGAGCTGAAGGACTCTTGCCGTAGATTAAGCCAGTC AGTTGCAATGTGCAAGACAGGCTGCTTGCCGGGCCGCCCTCGGAACATCTGGCCCAGCAGGCCCAGACTGTATCCATCCAAGTTCCCGTT GTATCCAGAGTTCTTAGAGCTTGTGTCTAAAGGGTAATTCCCCAACCCTTCCTTATGAGCATTTTTAGAACATTGGCTAAGACTATTTTC CCCCAGTAGCGCTTTTTTCTGGATTTGCATTCAGGTGTTATTCTTAATGTTTCTGTCAAAGCTTCTTAAAAATCTTCACTTGGTTTCAGC CATAGTTCACCTTCCCTGTTCCAGGTTTATTTAATTCCAAAGGTGAGAGTTGGAGTGAGATGTCTTCCATATCTATACCTTTGTGCACAG TTGAATGGGAACTGTTTGGGTTTAGGGCATCTTAGAGTTGATTGATGGAAAAAGCAGACAGGAACTGGTGGGAGGTCAAGTGGGGAAGTT GGTGAATGTGGAATAACTTACCTTTGTGCTCCACTTAAACCAGATGTGTTGCAGCTTTCCTGACATGCAAGGATCTACTTTAATTCCACA CTCTCATTAATAAATTGAATAAAAGGGAATGTTTTGGCACCTGATATAATCTGCCAGGCTATGTGACAGTAGGAAGGAATGGTTTCCCCT >In-frame_ENST00000389272_ENST00000368521_TCGA-G3-A7M7-01A_STAT3_chr17_40497577_-_C1orf43_chr1_154180124_length(amino acids)=144AA_start in transcript=158_stop in transcript=592 MRPAKNHMPLWCFIISWERLTSSIAASCKSRMFSISTIYEESSSFFRAGILRSQWRLPGLWPGACGKNHAFYRLQPLRPRVKARIGSSQR -------------------------------------------------------------- >In-frame_ENST00000389272_ENST00000350592_TCGA-G3-A7M7-01A_STAT3_chr17_40497577_-_C1orf43_chr1_154180124_length(transcript)=1326nt_BP=397nt GGGAACAAGCCCCAACCGGATCCTGGACAGGCACCCCGGCTTGGCGCTGTCTCTCCCCCTCGGCTCGGAGAGGCCCTTCGGCCTGAGGGA GCCTCGCCGCCCGTCCCCGGCACACGCGCAGCCCCGGCCTCTCGGCCTCTGCCGGAGAAACAGGGCATATGCGGCCAGCAAAGAATCACA TGCCACTTTGGTGTTTCATAATCTCCTGGGAGAGATTGACCAGCAGTATAGCCGCTTCCTGCAAGAGTCGAATGTTCTCTATCAGCACAA TCTACGAAGAATCAAGCAGTTTCTTCAGAGCAGGTATCTTGAGAAGCCAATGGAGATTGCCCGGATTGTGGCCCGGTGCCTGTGGGAAGA ATCACGCCTTCTACAGACTGCAGCCACTGCGGCCCAGGGTTAAAGCACGAATTGGGAGCTCTCAGCGACATCACCAGTCAGCAGCCAAAG ACCTAACTCAGTCCCCTGAGGTCTCCCCAACAACCATCCAGGTGACATACCTCCCCTCCAGTCAGAAGAGTAAACGTGCCAAGCACTTCC TTGAATTGAAGAGCTTTAAGGATAACTATAACACATTGGAGAGTACTCTGTGACGGAGCTGAAGGACTCTTGCCGTAGATTAAGCCAGTC AGTTGCAATGTGCAAGACAGGCTGCTTGCCGGGCCGCCCTCGGAACATCTGGCCCAGCAGGCCCAGACTGTATCCATCCAAGTTCCCGTT GTATCCAGAGTTCTTAGAGCTTGTGTCTAAAGGGTAATTCCCCAACCCTTCCTTATGAGCATTTTTAGAACATTGGCTAAGACTATTTTC CCCCAGTAGCGCTTTTTTCTGGATTTGCATTCAGGTGTTATTCTTAATGTTTCTGTCAAAGCTTCTTAAAAATCTTCACTTGGTTTCAGC CATAGTTCACCTTCCCTGTTCCAGGTTTATTTAATTCCAAAGGTGAGAGTTGGAGTGAGATGTCTTCCATATCTATACCTTTGTGCACAG TTGAATGGGAACTGTTTGGGTTTAGGGCATCTTAGAGTTGATTGATGGAAAAAGCAGACAGGAACTGGTGGGAGGTCAAGTGGGGAAGTT GGTGAATGTGGAATAACTTACCTTTGTGCTCCACTTAAACCAGATGTGTTGCAGCTTTCCTGACATGCAAGGATCTACTTTAATTCCACA CTCTCATTAATAAATTGAATAAAAGGGAATGTTTTGGCACCTGATATAATCTGCCAGGCTATGTGACAGTAGGAAGGAATGGTTTCCCCT >In-frame_ENST00000389272_ENST00000350592_TCGA-G3-A7M7-01A_STAT3_chr17_40497577_-_C1orf43_chr1_154180124_length(amino acids)=144AA_start in transcript=158_stop in transcript=592 MRPAKNHMPLWCFIISWERLTSSIAASCKSRMFSISTIYEESSSFFRAGILRSQWRLPGLWPGACGKNHAFYRLQPLRPRVKARIGSSQR -------------------------------------------------------------- >In-frame_ENST00000389272_ENST00000368519_TCGA-G3-A7M7-01A_STAT3_chr17_40497577_-_C1orf43_chr1_154180124_length(transcript)=870nt_BP=397nt GGGAACAAGCCCCAACCGGATCCTGGACAGGCACCCCGGCTTGGCGCTGTCTCTCCCCCTCGGCTCGGAGAGGCCCTTCGGCCTGAGGGA GCCTCGCCGCCCGTCCCCGGCACACGCGCAGCCCCGGCCTCTCGGCCTCTGCCGGAGAAACAGGGCATATGCGGCCAGCAAAGAATCACA TGCCACTTTGGTGTTTCATAATCTCCTGGGAGAGATTGACCAGCAGTATAGCCGCTTCCTGCAAGAGTCGAATGTTCTCTATCAGCACAA TCTACGAAGAATCAAGCAGTTTCTTCAGAGCAGGTATCTTGAGAAGCCAATGGAGATTGCCCGGATTGTGGCCCGGTGCCTGTGGGAAGA ATCACGCCTTCTACAGACTGCAGCCACTGCGGCCCAGGGTTAAAGCACGAATTGGGAGCTCTCAGCGACATCACCAGTCAGCAGCCAAAG ACCTAACTCAGTCCCCTGAGGTCTCCCCAACAACCATCCAGGTGACATACCTCCCCTCCAGTCAGAAGAGTAAACGTGCCAAGCACTTCC TTGAATTGAAGAGCTTTAAGGATAACTATAACACATTGGAGAGTACTCTGTGACGGAGCTGAAGGACTCTTGCCGTAGATTAAGCCAGTC AGTTGCAATGTGCAAGACAGGCTGCTTGCCGGGCCGCCCTCGGAACATCTGGCCCAGCAGGCCCAGACTGTATCCATCCAAGTTCCCGTT GTATCCAGAGTTCTTAGAGCTTGTGTCTAAAGGGTAATTCCCCAACCCTTCCTTATGAGCATTTTTAGAACATTGGCTAAGACTATTTTC >In-frame_ENST00000389272_ENST00000368519_TCGA-G3-A7M7-01A_STAT3_chr17_40497577_-_C1orf43_chr1_154180124_length(amino acids)=144AA_start in transcript=158_stop in transcript=592 MRPAKNHMPLWCFIISWERLTSSIAASCKSRMFSISTIYEESSSFFRAGILRSQWRLPGLWPGACGKNHAFYRLQPLRPRVKARIGSSQR -------------------------------------------------------------- >In-frame_ENST00000588969_ENST00000368521_TCGA-G3-A7M7-01A_STAT3_chr17_40497577_-_C1orf43_chr1_154180124_length(transcript)=1520nt_BP=577nt GCGGCGGCGCAGACTGGGAGGGGGAGCCGGGGGTTCCGACGTCGCAGCCGAGGGAACAAGCCCCAACCGGATCCTGGACAGGCACCCCGG CTTGGCGCTGTCTCTCCCCCTCGGCTCGGAGAGGCCCTTCGGCCTGAGGGAGCCTCGCCGCCCGTCCCCGGCACACGCGCAGCCCCGGCC TCTCGGCCTCTGCCGGAGAAACAGGATGGCCCAATGGAATCAGCTACAGCAGCTTGACACACGGTACCTGGAGCAGCTCCATCAGCTCTA CAGTGACAGCTTCCCAATGGAGCTGCGGCAGTTTCTGGCCCCTTGGATTGAGAGTCAAGATTGGGCATATGCGGCCAGCAAAGAATCACA TGCCACTTTGGTGTTTCATAATCTCCTGGGAGAGATTGACCAGCAGTATAGCCGCTTCCTGCAAGAGTCGAATGTTCTCTATCAGCACAA TCTACGAAGAATCAAGCAGTTTCTTCAGAGCAGGTATCTTGAGAAGCCAATGGAGATTGCCCGGATTGTGGCCCGGTGCCTGTGGGAAGA ATCACGCCTTCTACAGACTGCAGCCACTGCGGCCCAGGGTTAAAGCACGAATTGGGAGCTCTCAGCGACATCACCAGTCAGCAGCCAAAG ACCTAACTCAGTCCCCTGAGGTCTCCCCAACAACCATCCAGGTGACATACCTCCCCTCCAGTCAGAAGAGTAAACGTGCCAAGCACTTCC TTGAATTGAAGAGCTTTAAGGATAACTATAACACATTGGAGAGTACTCTGTGACGGAGCTGAAGGACTCTTGCCGTAGATTAAGCCAGTC AGTTGCAATGTGCAAGACAGGCTGCTTGCCGGGCCGCCCTCGGAACATCTGGCCCAGCAGGCCCAGACTGTATCCATCCAAGTTCCCGTT GTATCCAGAGTTCTTAGAGCTTGTGTCTAAAGGGTAATTCCCCAACCCTTCCTTATGAGCATTTTTAGAACATTGGCTAAGACTATTTTC CCCCAGTAGCGCTTTTTTCTGGATTTGCATTCAGGTGTTATTCTTAATGTTTCTGTCAAAGCTTCTTAAAAATCTTCACTTGGTTTCAGC CATAGTTCACCTTCCCTGTTCCAGGTTTATTTAATTCCAAAGGTGAGAGTTGGAGTGAGATGTCTTCCATATCTATACCTTTGTGCACAG TTGAATGGGAACTGTTTGGGTTTAGGGCATCTTAGAGTTGATTGATGGAAAAAGCAGACAGGAACTGGTGGGAGGTCAAGTGGGGAAGTT GGTGAATGTGGAATAACTTACCTTTGTGCTCCACTTAAACCAGATGTGTTGCAGCTTTCCTGACATGCAAGGATCTACTTTAATTCCACA CTCTCATTAATAAATTGAATAAAAGGGAATGTTTTGGCACCTGATATAATCTGCCAGGCTATGTGACAGTAGGAAGGAATGGTTTCCCCT >In-frame_ENST00000588969_ENST00000368521_TCGA-G3-A7M7-01A_STAT3_chr17_40497577_-_C1orf43_chr1_154180124_length(amino acids)=189AA_start in transcript=13_stop in transcript=582 MGGGAGGSDVAAEGTSPNRILDRHPGLALSLPLGSERPFGLREPRRPSPAHAQPRPLGLCRRNRMAQWNQLQQLDTRYLEQLHQLYSDSF PMELRQFLAPWIESQDWAYAASKESHATLVFHNLLGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLL -------------------------------------------------------------- >In-frame_ENST00000588969_ENST00000350592_TCGA-G3-A7M7-01A_STAT3_chr17_40497577_-_C1orf43_chr1_154180124_length(transcript)=1506nt_BP=577nt GCGGCGGCGCAGACTGGGAGGGGGAGCCGGGGGTTCCGACGTCGCAGCCGAGGGAACAAGCCCCAACCGGATCCTGGACAGGCACCCCGG CTTGGCGCTGTCTCTCCCCCTCGGCTCGGAGAGGCCCTTCGGCCTGAGGGAGCCTCGCCGCCCGTCCCCGGCACACGCGCAGCCCCGGCC TCTCGGCCTCTGCCGGAGAAACAGGATGGCCCAATGGAATCAGCTACAGCAGCTTGACACACGGTACCTGGAGCAGCTCCATCAGCTCTA CAGTGACAGCTTCCCAATGGAGCTGCGGCAGTTTCTGGCCCCTTGGATTGAGAGTCAAGATTGGGCATATGCGGCCAGCAAAGAATCACA TGCCACTTTGGTGTTTCATAATCTCCTGGGAGAGATTGACCAGCAGTATAGCCGCTTCCTGCAAGAGTCGAATGTTCTCTATCAGCACAA TCTACGAAGAATCAAGCAGTTTCTTCAGAGCAGGTATCTTGAGAAGCCAATGGAGATTGCCCGGATTGTGGCCCGGTGCCTGTGGGAAGA ATCACGCCTTCTACAGACTGCAGCCACTGCGGCCCAGGGTTAAAGCACGAATTGGGAGCTCTCAGCGACATCACCAGTCAGCAGCCAAAG ACCTAACTCAGTCCCCTGAGGTCTCCCCAACAACCATCCAGGTGACATACCTCCCCTCCAGTCAGAAGAGTAAACGTGCCAAGCACTTCC TTGAATTGAAGAGCTTTAAGGATAACTATAACACATTGGAGAGTACTCTGTGACGGAGCTGAAGGACTCTTGCCGTAGATTAAGCCAGTC AGTTGCAATGTGCAAGACAGGCTGCTTGCCGGGCCGCCCTCGGAACATCTGGCCCAGCAGGCCCAGACTGTATCCATCCAAGTTCCCGTT GTATCCAGAGTTCTTAGAGCTTGTGTCTAAAGGGTAATTCCCCAACCCTTCCTTATGAGCATTTTTAGAACATTGGCTAAGACTATTTTC CCCCAGTAGCGCTTTTTTCTGGATTTGCATTCAGGTGTTATTCTTAATGTTTCTGTCAAAGCTTCTTAAAAATCTTCACTTGGTTTCAGC CATAGTTCACCTTCCCTGTTCCAGGTTTATTTAATTCCAAAGGTGAGAGTTGGAGTGAGATGTCTTCCATATCTATACCTTTGTGCACAG TTGAATGGGAACTGTTTGGGTTTAGGGCATCTTAGAGTTGATTGATGGAAAAAGCAGACAGGAACTGGTGGGAGGTCAAGTGGGGAAGTT GGTGAATGTGGAATAACTTACCTTTGTGCTCCACTTAAACCAGATGTGTTGCAGCTTTCCTGACATGCAAGGATCTACTTTAATTCCACA CTCTCATTAATAAATTGAATAAAAGGGAATGTTTTGGCACCTGATATAATCTGCCAGGCTATGTGACAGTAGGAAGGAATGGTTTCCCCT >In-frame_ENST00000588969_ENST00000350592_TCGA-G3-A7M7-01A_STAT3_chr17_40497577_-_C1orf43_chr1_154180124_length(amino acids)=189AA_start in transcript=13_stop in transcript=582 MGGGAGGSDVAAEGTSPNRILDRHPGLALSLPLGSERPFGLREPRRPSPAHAQPRPLGLCRRNRMAQWNQLQQLDTRYLEQLHQLYSDSF PMELRQFLAPWIESQDWAYAASKESHATLVFHNLLGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLL -------------------------------------------------------------- >In-frame_ENST00000588969_ENST00000368519_TCGA-G3-A7M7-01A_STAT3_chr17_40497577_-_C1orf43_chr1_154180124_length(transcript)=1050nt_BP=577nt GCGGCGGCGCAGACTGGGAGGGGGAGCCGGGGGTTCCGACGTCGCAGCCGAGGGAACAAGCCCCAACCGGATCCTGGACAGGCACCCCGG CTTGGCGCTGTCTCTCCCCCTCGGCTCGGAGAGGCCCTTCGGCCTGAGGGAGCCTCGCCGCCCGTCCCCGGCACACGCGCAGCCCCGGCC TCTCGGCCTCTGCCGGAGAAACAGGATGGCCCAATGGAATCAGCTACAGCAGCTTGACACACGGTACCTGGAGCAGCTCCATCAGCTCTA CAGTGACAGCTTCCCAATGGAGCTGCGGCAGTTTCTGGCCCCTTGGATTGAGAGTCAAGATTGGGCATATGCGGCCAGCAAAGAATCACA TGCCACTTTGGTGTTTCATAATCTCCTGGGAGAGATTGACCAGCAGTATAGCCGCTTCCTGCAAGAGTCGAATGTTCTCTATCAGCACAA TCTACGAAGAATCAAGCAGTTTCTTCAGAGCAGGTATCTTGAGAAGCCAATGGAGATTGCCCGGATTGTGGCCCGGTGCCTGTGGGAAGA ATCACGCCTTCTACAGACTGCAGCCACTGCGGCCCAGGGTTAAAGCACGAATTGGGAGCTCTCAGCGACATCACCAGTCAGCAGCCAAAG ACCTAACTCAGTCCCCTGAGGTCTCCCCAACAACCATCCAGGTGACATACCTCCCCTCCAGTCAGAAGAGTAAACGTGCCAAGCACTTCC TTGAATTGAAGAGCTTTAAGGATAACTATAACACATTGGAGAGTACTCTGTGACGGAGCTGAAGGACTCTTGCCGTAGATTAAGCCAGTC AGTTGCAATGTGCAAGACAGGCTGCTTGCCGGGCCGCCCTCGGAACATCTGGCCCAGCAGGCCCAGACTGTATCCATCCAAGTTCCCGTT GTATCCAGAGTTCTTAGAGCTTGTGTCTAAAGGGTAATTCCCCAACCCTTCCTTATGAGCATTTTTAGAACATTGGCTAAGACTATTTTC >In-frame_ENST00000588969_ENST00000368519_TCGA-G3-A7M7-01A_STAT3_chr17_40497577_-_C1orf43_chr1_154180124_length(amino acids)=189AA_start in transcript=13_stop in transcript=582 MGGGAGGSDVAAEGTSPNRILDRHPGLALSLPLGSERPFGLREPRRPSPAHAQPRPLGLCRRNRMAQWNQLQQLDTRYLEQLHQLYSDSF PMELRQFLAPWIESQDWAYAASKESHATLVFHNLLGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLL -------------------------------------------------------------- >In-frame_ENST00000404395_ENST00000368521_TCGA-G3-A7M7-01A_STAT3_chr17_40497577_-_C1orf43_chr1_154180124_length(transcript)=1452nt_BP=509nt GGATCCTGGACAGGCACCCCGGCTTGGCGCTGTCTCTCCCCCTCGGCTCGGAGAGGCCCTTCGGCCTGAGGGAGCCTCGCCGCCCGTCCC CGGCACACGCGCAGCCCCGGCCTCTCGGCCTCTGCCGGAGAAACAGGATGGCCCAATGGAATCAGCTACAGCAGCTTGACACACGGTACC TGGAGCAGCTCCATCAGCTCTACAGTGACAGCTTCCCAATGGAGCTGCGGCAGTTTCTGGCCCCTTGGATTGAGAGTCAAGATTGGGCAT ATGCGGCCAGCAAAGAATCACATGCCACTTTGGTGTTTCATAATCTCCTGGGAGAGATTGACCAGCAGTATAGCCGCTTCCTGCAAGAGT CGAATGTTCTCTATCAGCACAATCTACGAAGAATCAAGCAGTTTCTTCAGAGCAGGTATCTTGAGAAGCCAATGGAGATTGCCCGGATTG TGGCCCGGTGCCTGTGGGAAGAATCACGCCTTCTACAGACTGCAGCCACTGCGGCCCAGGGTTAAAGCACGAATTGGGAGCTCTCAGCGA CATCACCAGTCAGCAGCCAAAGACCTAACTCAGTCCCCTGAGGTCTCCCCAACAACCATCCAGGTGACATACCTCCCCTCCAGTCAGAAG AGTAAACGTGCCAAGCACTTCCTTGAATTGAAGAGCTTTAAGGATAACTATAACACATTGGAGAGTACTCTGTGACGGAGCTGAAGGACT CTTGCCGTAGATTAAGCCAGTCAGTTGCAATGTGCAAGACAGGCTGCTTGCCGGGCCGCCCTCGGAACATCTGGCCCAGCAGGCCCAGAC TGTATCCATCCAAGTTCCCGTTGTATCCAGAGTTCTTAGAGCTTGTGTCTAAAGGGTAATTCCCCAACCCTTCCTTATGAGCATTTTTAG AACATTGGCTAAGACTATTTTCCCCCAGTAGCGCTTTTTTCTGGATTTGCATTCAGGTGTTATTCTTAATGTTTCTGTCAAAGCTTCTTA AAAATCTTCACTTGGTTTCAGCCATAGTTCACCTTCCCTGTTCCAGGTTTATTTAATTCCAAAGGTGAGAGTTGGAGTGAGATGTCTTCC ATATCTATACCTTTGTGCACAGTTGAATGGGAACTGTTTGGGTTTAGGGCATCTTAGAGTTGATTGATGGAAAAAGCAGACAGGAACTGG TGGGAGGTCAAGTGGGGAAGTTGGTGAATGTGGAATAACTTACCTTTGTGCTCCACTTAAACCAGATGTGTTGCAGCTTTCCTGACATGC AAGGATCTACTTTAATTCCACACTCTCATTAATAAATTGAATAAAAGGGAATGTTTTGGCACCTGATATAATCTGCCAGGCTATGTGACA GTAGGAAGGAATGGTTTCCCCTAACAAGCCCAATGCACTGGTCTGACTTTATAAATTATTTAATAAAATGAACTATTATCAAATAAAACG >In-frame_ENST00000404395_ENST00000368521_TCGA-G3-A7M7-01A_STAT3_chr17_40497577_-_C1orf43_chr1_154180124_length(amino acids)=179AA_start in transcript=165_stop in transcript=704 MTHGTWSSSISSTVTASQWSCGSFWPLGLRVKIGHMRPAKNHMPLWCFIISWERLTSSIAASCKSRMFSISTIYEESSSFFRAGILRSQW -------------------------------------------------------------- >In-frame_ENST00000404395_ENST00000350592_TCGA-G3-A7M7-01A_STAT3_chr17_40497577_-_C1orf43_chr1_154180124_length(transcript)=1438nt_BP=509nt GGATCCTGGACAGGCACCCCGGCTTGGCGCTGTCTCTCCCCCTCGGCTCGGAGAGGCCCTTCGGCCTGAGGGAGCCTCGCCGCCCGTCCC CGGCACACGCGCAGCCCCGGCCTCTCGGCCTCTGCCGGAGAAACAGGATGGCCCAATGGAATCAGCTACAGCAGCTTGACACACGGTACC TGGAGCAGCTCCATCAGCTCTACAGTGACAGCTTCCCAATGGAGCTGCGGCAGTTTCTGGCCCCTTGGATTGAGAGTCAAGATTGGGCAT ATGCGGCCAGCAAAGAATCACATGCCACTTTGGTGTTTCATAATCTCCTGGGAGAGATTGACCAGCAGTATAGCCGCTTCCTGCAAGAGT CGAATGTTCTCTATCAGCACAATCTACGAAGAATCAAGCAGTTTCTTCAGAGCAGGTATCTTGAGAAGCCAATGGAGATTGCCCGGATTG TGGCCCGGTGCCTGTGGGAAGAATCACGCCTTCTACAGACTGCAGCCACTGCGGCCCAGGGTTAAAGCACGAATTGGGAGCTCTCAGCGA CATCACCAGTCAGCAGCCAAAGACCTAACTCAGTCCCCTGAGGTCTCCCCAACAACCATCCAGGTGACATACCTCCCCTCCAGTCAGAAG AGTAAACGTGCCAAGCACTTCCTTGAATTGAAGAGCTTTAAGGATAACTATAACACATTGGAGAGTACTCTGTGACGGAGCTGAAGGACT CTTGCCGTAGATTAAGCCAGTCAGTTGCAATGTGCAAGACAGGCTGCTTGCCGGGCCGCCCTCGGAACATCTGGCCCAGCAGGCCCAGAC TGTATCCATCCAAGTTCCCGTTGTATCCAGAGTTCTTAGAGCTTGTGTCTAAAGGGTAATTCCCCAACCCTTCCTTATGAGCATTTTTAG AACATTGGCTAAGACTATTTTCCCCCAGTAGCGCTTTTTTCTGGATTTGCATTCAGGTGTTATTCTTAATGTTTCTGTCAAAGCTTCTTA AAAATCTTCACTTGGTTTCAGCCATAGTTCACCTTCCCTGTTCCAGGTTTATTTAATTCCAAAGGTGAGAGTTGGAGTGAGATGTCTTCC ATATCTATACCTTTGTGCACAGTTGAATGGGAACTGTTTGGGTTTAGGGCATCTTAGAGTTGATTGATGGAAAAAGCAGACAGGAACTGG TGGGAGGTCAAGTGGGGAAGTTGGTGAATGTGGAATAACTTACCTTTGTGCTCCACTTAAACCAGATGTGTTGCAGCTTTCCTGACATGC AAGGATCTACTTTAATTCCACACTCTCATTAATAAATTGAATAAAAGGGAATGTTTTGGCACCTGATATAATCTGCCAGGCTATGTGACA >In-frame_ENST00000404395_ENST00000350592_TCGA-G3-A7M7-01A_STAT3_chr17_40497577_-_C1orf43_chr1_154180124_length(amino acids)=179AA_start in transcript=165_stop in transcript=704 MTHGTWSSSISSTVTASQWSCGSFWPLGLRVKIGHMRPAKNHMPLWCFIISWERLTSSIAASCKSRMFSISTIYEESSSFFRAGILRSQW -------------------------------------------------------------- >In-frame_ENST00000404395_ENST00000368519_TCGA-G3-A7M7-01A_STAT3_chr17_40497577_-_C1orf43_chr1_154180124_length(transcript)=982nt_BP=509nt GGATCCTGGACAGGCACCCCGGCTTGGCGCTGTCTCTCCCCCTCGGCTCGGAGAGGCCCTTCGGCCTGAGGGAGCCTCGCCGCCCGTCCC CGGCACACGCGCAGCCCCGGCCTCTCGGCCTCTGCCGGAGAAACAGGATGGCCCAATGGAATCAGCTACAGCAGCTTGACACACGGTACC TGGAGCAGCTCCATCAGCTCTACAGTGACAGCTTCCCAATGGAGCTGCGGCAGTTTCTGGCCCCTTGGATTGAGAGTCAAGATTGGGCAT ATGCGGCCAGCAAAGAATCACATGCCACTTTGGTGTTTCATAATCTCCTGGGAGAGATTGACCAGCAGTATAGCCGCTTCCTGCAAGAGT CGAATGTTCTCTATCAGCACAATCTACGAAGAATCAAGCAGTTTCTTCAGAGCAGGTATCTTGAGAAGCCAATGGAGATTGCCCGGATTG TGGCCCGGTGCCTGTGGGAAGAATCACGCCTTCTACAGACTGCAGCCACTGCGGCCCAGGGTTAAAGCACGAATTGGGAGCTCTCAGCGA CATCACCAGTCAGCAGCCAAAGACCTAACTCAGTCCCCTGAGGTCTCCCCAACAACCATCCAGGTGACATACCTCCCCTCCAGTCAGAAG AGTAAACGTGCCAAGCACTTCCTTGAATTGAAGAGCTTTAAGGATAACTATAACACATTGGAGAGTACTCTGTGACGGAGCTGAAGGACT CTTGCCGTAGATTAAGCCAGTCAGTTGCAATGTGCAAGACAGGCTGCTTGCCGGGCCGCCCTCGGAACATCTGGCCCAGCAGGCCCAGAC TGTATCCATCCAAGTTCCCGTTGTATCCAGAGTTCTTAGAGCTTGTGTCTAAAGGGTAATTCCCCAACCCTTCCTTATGAGCATTTTTAG >In-frame_ENST00000404395_ENST00000368519_TCGA-G3-A7M7-01A_STAT3_chr17_40497577_-_C1orf43_chr1_154180124_length(amino acids)=179AA_start in transcript=165_stop in transcript=704 MTHGTWSSSISSTVTASQWSCGSFWPLGLRVKIGHMRPAKNHMPLWCFIISWERLTSSIAASCKSRMFSISTIYEESSSFFRAGILRSQW -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for STAT3-C1orf43 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for STAT3-C1orf43 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for STAT3-C1orf43 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | STAT3 | C4721531 | HYPER-IgE RECURRENT INFECTION SYNDROME 1, AUTOSOMAL DOMINANT | 7 | GENOMICS_ENGLAND;UNIPROT |
| Hgene | STAT3 | C0018800 | Cardiomegaly | 3 | CTD_human |
| Hgene | STAT3 | C0021368 | Inflammation | 3 | CTD_human |
| Hgene | STAT3 | C0033578 | Prostatic Neoplasms | 3 | CTD_human |
| Hgene | STAT3 | C0376358 | Malignant neoplasm of prostate | 3 | CTD_human |
| Hgene | STAT3 | C1383860 | Cardiac Hypertrophy | 3 | CTD_human |
| Hgene | STAT3 | C2936739 | Hyper-Immunoglobulin E Syndrome, Autosomal Dominant | 3 | CTD_human;ORPHANET |
| Hgene | STAT3 | C3887645 | Job Syndrome | 3 | CTD_human;GENOMICS_ENGLAND;ORPHANET |
| Hgene | STAT3 | C4014795 | AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 1 | 3 | CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT |
| Hgene | STAT3 | C0001418 | Adenocarcinoma | 2 | CTD_human |
| Hgene | STAT3 | C0003865 | Arthritis, Adjuvant-Induced | 2 | CTD_human |
| Hgene | STAT3 | C0007137 | Squamous cell carcinoma | 2 | CTD_human |
| Hgene | STAT3 | C0009324 | Ulcerative Colitis | 2 | CTD_human |
| Hgene | STAT3 | C0019207 | Hepatoma, Morris | 2 | CTD_human |
| Hgene | STAT3 | C0019208 | Hepatoma, Novikoff | 2 | CTD_human |
| Hgene | STAT3 | C0023904 | Liver Neoplasms, Experimental | 2 | CTD_human |
| Hgene | STAT3 | C0027627 | Neoplasm Metastasis | 2 | CTD_human |
| Hgene | STAT3 | C0030297 | Pancreatic Neoplasm | 2 | CTD_human |
| Hgene | STAT3 | C0033141 | Cardiomyopathies, Primary | 2 | CTD_human |
| Hgene | STAT3 | C0036529 | Myocardial Diseases, Secondary | 2 | CTD_human |
| Hgene | STAT3 | C0086404 | Experimental Hepatoma | 2 | CTD_human |
| Hgene | STAT3 | C0205641 | Adenocarcinoma, Basal Cell | 2 | CTD_human |
| Hgene | STAT3 | C0205642 | Adenocarcinoma, Oxyphilic | 2 | CTD_human |
| Hgene | STAT3 | C0205643 | Carcinoma, Cribriform | 2 | CTD_human |
| Hgene | STAT3 | C0205644 | Carcinoma, Granular Cell | 2 | CTD_human |
| Hgene | STAT3 | C0205645 | Adenocarcinoma, Tubular | 2 | CTD_human |
| Hgene | STAT3 | C0346647 | Malignant neoplasm of pancreas | 2 | CTD_human |
| Hgene | STAT3 | C0878544 | Cardiomyopathies | 2 | CTD_human |
| Hgene | STAT3 | C0971858 | Arthritis, Collagen-Induced | 2 | CTD_human |
| Hgene | STAT3 | C0993582 | Arthritis, Experimental | 2 | CTD_human |
| Hgene | STAT3 | C1955861 | T-Cell Large Granular Lymphocyte Leukemia | 2 | CGI;ORPHANET |
| Hgene | STAT3 | C2930809 | Neutropenia and hyperlymphocytosis with large granular lymphocytes | 2 | ORPHANET |
| Hgene | STAT3 | C3489795 | Hyper-Ige Recurrent Infection Syndrome, Autosomal Dominant | 2 | CTD_human;ORPHANET |
| Hgene | STAT3 | C0004153 | Atherosclerosis | 1 | CTD_human |
| Hgene | STAT3 | C0004364 | Autoimmune Diseases | 1 | CTD_human |
| Hgene | STAT3 | C0006142 | Malignant neoplasm of breast | 1 | CTD_human |
| Hgene | STAT3 | C0007097 | Carcinoma | 1 | CTD_human |
| Hgene | STAT3 | C0007102 | Malignant tumor of colon | 1 | CTD_human |
| Hgene | STAT3 | C0007131 | Non-Small Cell Lung Carcinoma | 1 | CTD_human |
| Hgene | STAT3 | C0007621 | Neoplastic Cell Transformation | 1 | CTD_human |
| Hgene | STAT3 | C0007786 | Brain Ischemia | 1 | CTD_human |
| Hgene | STAT3 | C0007873 | Uterine Cervical Neoplasm | 1 | CTD_human |
| Hgene | STAT3 | C0009375 | Colonic Neoplasms | 1 | CTD_human |
| Hgene | STAT3 | C0011581 | Depressive disorder | 1 | PSYGENET |
| Hgene | STAT3 | C0011854 | Diabetes Mellitus, Insulin-Dependent | 1 | CTD_human |
| Hgene | STAT3 | C0015967 | Fever | 1 | CTD_human |
| Hgene | STAT3 | C0016059 | Fibrosis | 1 | CTD_human |
| Hgene | STAT3 | C0019189 | Hepatitis, Chronic | 1 | CTD_human |
| Hgene | STAT3 | C0023467 | Leukemia, Myelocytic, Acute | 1 | CTD_human |
| Hgene | STAT3 | C0023485 | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma | 1 | CTD_human |
| Hgene | STAT3 | C0023487 | Acute Promyelocytic Leukemia | 1 | ORPHANET |
| Hgene | STAT3 | C0023492 | Leukemia, T-Cell | 1 | CTD_human |
| Hgene | STAT3 | C0023493 | Adult T-Cell Lymphoma/Leukemia | 1 | CTD_human |
| Hgene | STAT3 | C0023903 | Liver neoplasms | 1 | CTD_human |
| Hgene | STAT3 | C0024232 | Lymphatic Metastasis | 1 | CTD_human |
| Hgene | STAT3 | C0024623 | Malignant neoplasm of stomach | 1 | CTD_human |
| Hgene | STAT3 | C0024667 | Animal Mammary Neoplasms | 1 | CTD_human |
| Hgene | STAT3 | C0024668 | Mammary Neoplasms, Experimental | 1 | CTD_human |
| Hgene | STAT3 | C0025149 | Medulloblastoma | 1 | CTD_human |
| Hgene | STAT3 | C0025261 | Memory Disorders | 1 | CTD_human |
| Hgene | STAT3 | C0026998 | Acute Myeloid Leukemia, M1 | 1 | CTD_human |
| Hgene | STAT3 | C0027659 | Neoplasms, Experimental | 1 | CTD_human |
| Hgene | STAT3 | C0030246 | Pustulosis of Palms and Soles | 1 | CTD_human |
| Hgene | STAT3 | C0032927 | Precancerous Conditions | 1 | CTD_human |
| Hgene | STAT3 | C0033860 | Psoriasis | 1 | CTD_human |
| Hgene | STAT3 | C0034069 | Pulmonary Fibrosis | 1 | CTD_human |
| Hgene | STAT3 | C0035126 | Reperfusion Injury | 1 | CTD_human |
| Hgene | STAT3 | C0038356 | Stomach Neoplasms | 1 | CTD_human |
| Hgene | STAT3 | C0079772 | T-Cell Lymphoma | 1 | CTD_human |
| Hgene | STAT3 | C0087031 | Juvenile-Onset Still Disease | 1 | CTD_human |
| Hgene | STAT3 | C0149519 | Chronic Persistent Hepatitis | 1 | CTD_human |
| Hgene | STAT3 | C0158981 | Neonatal diabetes mellitus | 1 | GENOMICS_ENGLAND |
| Hgene | STAT3 | C0205696 | Anaplastic carcinoma | 1 | CTD_human |
| Hgene | STAT3 | C0205697 | Carcinoma, Spindle-Cell | 1 | CTD_human |
| Hgene | STAT3 | C0205698 | Undifferentiated carcinoma | 1 | CTD_human |
| Hgene | STAT3 | C0205699 | Carcinomatosis | 1 | CTD_human |
| Hgene | STAT3 | C0205734 | Diabetes, Autoimmune | 1 | CTD_human |
| Hgene | STAT3 | C0205833 | Medullomyoblastoma | 1 | CTD_human |
| Hgene | STAT3 | C0206180 | Ki-1+ Anaplastic Large Cell Lymphoma | 1 | CTD_human |
| Hgene | STAT3 | C0233794 | Memory impairment | 1 | CTD_human |
| Hgene | STAT3 | C0235833 | Congenital diaphragmatic hernia | 1 | CTD_human |
| Hgene | STAT3 | C0238281 | Middle Cerebral Artery Syndrome | 1 | CTD_human |
| Hgene | STAT3 | C0265699 | Congenital hernia of foramen of Morgagni | 1 | CTD_human |
| Hgene | STAT3 | C0265700 | Congenital hernia of foramen of Bochdalek | 1 | CTD_human |
| Hgene | STAT3 | C0278510 | Childhood Medulloblastoma | 1 | CTD_human |
| Hgene | STAT3 | C0278876 | Adult Medulloblastoma | 1 | CTD_human |
| Hgene | STAT3 | C0282313 | Condition, Preneoplastic | 1 | CTD_human |
| Hgene | STAT3 | C0333641 | Atrophic | 1 | CTD_human |
| Hgene | STAT3 | C0342302 | Brittle diabetes | 1 | CTD_human |
| Hgene | STAT3 | C0345904 | Malignant neoplasm of liver | 1 | CTD_human |
| Hgene | STAT3 | C0520463 | Chronic active hepatitis | 1 | CTD_human |
| Hgene | STAT3 | C0524611 | Cryptogenic Chronic Hepatitis | 1 | CTD_human |
| Hgene | STAT3 | C0678222 | Breast Carcinoma | 1 | CTD_human |
| Hgene | STAT3 | C0740376 | Middle Cerebral Artery Thrombosis | 1 | CTD_human |
| Hgene | STAT3 | C0740391 | Middle Cerebral Artery Occlusion | 1 | CTD_human |
| Hgene | STAT3 | C0740392 | Infarction, Middle Cerebral Artery | 1 | CTD_human |
| Hgene | STAT3 | C0751291 | Desmoplastic Medulloblastoma | 1 | CTD_human |
| Hgene | STAT3 | C0751292 | Age-Related Memory Disorders | 1 | CTD_human |
| Hgene | STAT3 | C0751293 | Memory Disorder, Semantic | 1 | CTD_human |
| Hgene | STAT3 | C0751294 | Memory Disorder, Spatial | 1 | CTD_human |
| Hgene | STAT3 | C0751295 | Memory Loss | 1 | CTD_human |
| Hgene | STAT3 | C0751845 | Middle Cerebral Artery Embolus | 1 | CTD_human |
| Hgene | STAT3 | C0751846 | Left Middle Cerebral Artery Infarction | 1 | CTD_human |
| Hgene | STAT3 | C0751847 | Embolic Infarction, Middle Cerebral Artery | 1 | CTD_human |
| Hgene | STAT3 | C0751848 | Thrombotic Infarction, Middle Cerebral Artery | 1 | CTD_human |
| Hgene | STAT3 | C0751849 | Right Middle Cerebral Artery Infarction | 1 | CTD_human |
| Hgene | STAT3 | C0917798 | Cerebral Ischemia | 1 | CTD_human |
| Hgene | STAT3 | C0919267 | ovarian neoplasm | 1 | CTD_human |
| Hgene | STAT3 | C1140680 | Malignant neoplasm of ovary | 1 | CTD_human |
| Hgene | STAT3 | C1168401 | Squamous cell carcinoma of the head and neck | 1 | CTD_human |
| Hgene | STAT3 | C1257925 | Mammary Carcinoma, Animal | 1 | CTD_human |
| Hgene | STAT3 | C1257931 | Mammary Neoplasms, Human | 1 | CTD_human |
| Hgene | STAT3 | C1275668 | Melanotic medulloblastoma | 1 | CTD_human |
| Hgene | STAT3 | C1458155 | Mammary Neoplasms | 1 | CTD_human |
| Hgene | STAT3 | C1512709 | Chronic Lymphoproliferative Disorder of NK-Cells | 1 | ORPHANET |
| Hgene | STAT3 | C1563937 | Atherogenesis | 1 | CTD_human |
| Hgene | STAT3 | C1623038 | Cirrhosis | 1 | CTD_human |
| Hgene | STAT3 | C1708349 | Hereditary Diffuse Gastric Cancer | 1 | CTD_human |
| Hgene | STAT3 | C1800706 | Idiopathic Pulmonary Fibrosis | 1 | CTD_human |
| Hgene | STAT3 | C1833104 | DIABETES MELLITUS, PERMANENT NEONATAL | 1 | ORPHANET |
| Hgene | STAT3 | C1876165 | Copper-Overload Cirrhosis | 1 | CTD_human |
| Hgene | STAT3 | C1879321 | Acute Myeloid Leukemia (AML-M2) | 1 | CTD_human |
| Hgene | STAT3 | C1968689 | Hyper-Immunoglobulin E Syndrome, Autosomal Recessive | 1 | CTD_human |
| Hgene | STAT3 | C3495559 | Juvenile arthritis | 1 | CTD_human |
| Hgene | STAT3 | C3714758 | Juvenile psoriatic arthritis | 1 | CTD_human |
| Hgene | STAT3 | C3837958 | Diabetes Mellitus, Ketosis-Prone | 1 | CTD_human |
| Hgene | STAT3 | C4048328 | cervical cancer | 1 | CTD_human |
| Hgene | STAT3 | C4552091 | Polyarthritis, Juvenile, Rheumatoid Factor Negative | 1 | CTD_human |
| Hgene | STAT3 | C4554117 | Diabetes Mellitus, Sudden-Onset | 1 | CTD_human |
| Hgene | STAT3 | C4704862 | Polyarthritis, Juvenile, Rheumatoid Factor Positive | 1 | CTD_human |
| Hgene | STAT3 | C4704874 | Mammary Carcinoma, Human | 1 | CTD_human |
| Hgene | STAT3 | C4721507 | Alveolitis, Fibrosing | 1 | CTD_human |
| Hgene | STAT3 | C4721508 | Hamman-Rich Disease | 1 | CTD_human |
| Hgene | STAT3 | C4721509 | Usual Interstitial Pneumonia | 1 | CTD_human |
| Hgene | STAT3 | C4721952 | Familial Idiopathic Pulmonary Fibrosis | 1 | CTD_human |
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