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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:STK11IP-S100A16 (FusionGDB2 ID:86852)

Fusion Gene Summary for STK11IP-S100A16

check button Fusion gene summary
Fusion gene informationFusion gene name: STK11IP-S100A16
Fusion gene ID: 86852
HgeneTgene
Gene symbol

STK11IP

S100A16

Gene ID

114790

388697

Gene nameserine/threonine kinase 11 interacting proteinhornerin
SynonymsLIP1|LKB1IP|STK11IP1FLG3|S100A16|S100a18
Cytomap

2q35

1q21.3

Type of geneprotein-codingprotein-coding
Descriptionserine/threonine-protein kinase 11-interacting proteinLKB1-interacting protein 1STK11 interacting proteinhornerinfilaggrin family member 3intermediate filament-associated protein
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000456909, ENST00000295641, 
ENST00000459692, 		ENST00000368704, 
ENST00000368706, ENST00000368703, 
ENST00000368705, ENST00000474991, 
Fusion gene scores* DoF score1 X 1 X 1=15 X 6 X 2=60
# samples 16
** MAII scorelog2(1/1*10)=3.32192809488736log2(6/60*10)=0
Context

PubMed: STK11IP [Title/Abstract] AND S100A16 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSTK11IP(220473038)-S100A16(153580599), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSTK11IP

GO:0008104

protein localization

11741830

TgeneS100A16

GO:0043163

cell envelope organization

21282207


check buttonFusion gene breakpoints across STK11IP (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across S100A16 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-BH-A0DZ-01ASTK11IPchr2

220473038

+S100A16chr1

153580599

-
ChimerDB4BRCATCGA-BH-A0DZ-01ASTK11IPchr2

220473038

+S100A16chr1

153580599

-


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Fusion Gene ORF analysis for STK11IP-S100A16

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000456909ENST00000368704STK11IPchr2

220473038

+S100A16chr1

153580599

-
In-frameENST00000456909ENST00000368706STK11IPchr2

220473038

+S100A16chr1

153580599

-
In-frameENST00000456909ENST00000368703STK11IPchr2

220473038

+S100A16chr1

153580599

-
In-frameENST00000456909ENST00000368705STK11IPchr2

220473038

+S100A16chr1

153580599

-
5CDS-5UTRENST00000456909ENST00000474991STK11IPchr2

220473038

+S100A16chr1

153580599

-
In-frameENST00000295641ENST00000368704STK11IPchr2

220473038

+S100A16chr1

153580599

-
In-frameENST00000295641ENST00000368706STK11IPchr2

220473038

+S100A16chr1

153580599

-
In-frameENST00000295641ENST00000368703STK11IPchr2

220473038

+S100A16chr1

153580599

-
In-frameENST00000295641ENST00000368705STK11IPchr2

220473038

+S100A16chr1

153580599

-
5CDS-5UTRENST00000295641ENST00000474991STK11IPchr2

220473038

+S100A16chr1

153580599

-
intron-3CDSENST00000459692ENST00000368704STK11IPchr2

220473038

+S100A16chr1

153580599

-
intron-3CDSENST00000459692ENST00000368706STK11IPchr2

220473038

+S100A16chr1

153580599

-
intron-3CDSENST00000459692ENST00000368703STK11IPchr2

220473038

+S100A16chr1

153580599

-
intron-3CDSENST00000459692ENST00000368705STK11IPchr2

220473038

+S100A16chr1

153580599

-
intron-5UTRENST00000459692ENST00000474991STK11IPchr2

220473038

+S100A16chr1

153580599

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000456909STK11IPchr2220473038+ENST00000368704S100A16chr1153580599-23551423901451453
ENST00000456909STK11IPchr2220473038+ENST00000368706S100A16chr1153580599-23551423901451453
ENST00000456909STK11IPchr2220473038+ENST00000368703S100A16chr1153580599-22661423901451453
ENST00000456909STK11IPchr2220473038+ENST00000368705S100A16chr1153580599-18791423901451453
ENST00000295641STK11IPchr2220473038+ENST00000368704S100A16chr1153580599-23411409761437453
ENST00000295641STK11IPchr2220473038+ENST00000368706S100A16chr1153580599-23411409761437453
ENST00000295641STK11IPchr2220473038+ENST00000368703S100A16chr1153580599-22521409761437453
ENST00000295641STK11IPchr2220473038+ENST00000368705S100A16chr1153580599-18651409761437453

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000456909ENST00000368704STK11IPchr2220473038+S100A16chr1153580599-0.0788645150.92113554
ENST00000456909ENST00000368706STK11IPchr2220473038+S100A16chr1153580599-0.0788645150.92113554
ENST00000456909ENST00000368703STK11IPchr2220473038+S100A16chr1153580599-0.082808280.91719174
ENST00000456909ENST00000368705STK11IPchr2220473038+S100A16chr1153580599-0.07928590.92071414
ENST00000295641ENST00000368704STK11IPchr2220473038+S100A16chr1153580599-0.078672510.92132753
ENST00000295641ENST00000368706STK11IPchr2220473038+S100A16chr1153580599-0.078672510.92132753
ENST00000295641ENST00000368703STK11IPchr2220473038+S100A16chr1153580599-0.081924950.9180751
ENST00000295641ENST00000368705STK11IPchr2220473038+S100A16chr1153580599-0.078660840.92133915

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Fusion Genomic Features for STK11IP-S100A16


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for STK11IP-S100A16


check button Go to

FGviewer for the breakpoints of chr2:220473038-chr1:153580599

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneS100A16chr2:220473038chr1:153580599ENST000003687030367_780104.0Calcium bindingHigh affinity
TgeneS100A16chr2:220473038chr1:153580599ENST000003687040367_780104.0Calcium bindingHigh affinity
TgeneS100A16chr2:220473038chr1:153580599ENST000003687050367_780104.0Calcium bindingHigh affinity
TgeneS100A16chr2:220473038chr1:153580599ENST000003687060367_780104.0Calcium bindingHigh affinity
TgeneS100A16chr2:220473038chr1:153580599ENST000003687030312_470104.0DomainEF-hand 1%3B degenerate
TgeneS100A16chr2:220473038chr1:153580599ENST000003687030354_890104.0DomainEF-hand 2
TgeneS100A16chr2:220473038chr1:153580599ENST000003687040312_470104.0DomainEF-hand 1%3B degenerate
TgeneS100A16chr2:220473038chr1:153580599ENST000003687040354_890104.0DomainEF-hand 2
TgeneS100A16chr2:220473038chr1:153580599ENST000003687050312_470104.0DomainEF-hand 1%3B degenerate
TgeneS100A16chr2:220473038chr1:153580599ENST000003687050354_890104.0DomainEF-hand 2
TgeneS100A16chr2:220473038chr1:153580599ENST000003687060312_470104.0DomainEF-hand 1%3B degenerate
TgeneS100A16chr2:220473038chr1:153580599ENST000003687060354_890104.0DomainEF-hand 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSTK11IPchr2:220473038chr1:153580599ENST00000295641+125474_59301100.0Compositional biasNote=Glu-rich
HgeneSTK11IPchr2:220473038chr1:153580599ENST00000295641+125109_13001100.0RepeatNote=LRR 1
HgeneSTK11IPchr2:220473038chr1:153580599ENST00000295641+125132_15201100.0RepeatNote=LRR 2
HgeneSTK11IPchr2:220473038chr1:153580599ENST00000295641+125164_18501100.0RepeatNote=LRR 3
HgeneSTK11IPchr2:220473038chr1:153580599ENST00000295641+125187_20901100.0RepeatNote=LRR 4
HgeneSTK11IPchr2:220473038chr1:153580599ENST00000295641+125210_23101100.0RepeatNote=LRR 5
HgeneSTK11IPchr2:220473038chr1:153580599ENST00000295641+125233_25401100.0RepeatNote=LRR 6
HgeneSTK11IPchr2:220473038chr1:153580599ENST00000295641+125255_27601100.0RepeatNote=LRR 7
HgeneSTK11IPchr2:220473038chr1:153580599ENST00000295641+125280_30101100.0RepeatNote=LRR 8


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Fusion Gene Sequence for STK11IP-S100A16


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000456909_ENST00000368704_TCGA-BH-A0DZ-01A_STK11IP_chr2_220473038_+_S100A16_chr1_153580599_length(transcript)=2355nt_BP=1423nt
TCCTTTCCATCATTGATAGGCGCCGGGCAGCTGAGCTGGTAGGAGGACCAGACGGGGAGGTTCGGCTCCGCCCCCCAGCGTCCCGTGGCC
ATGACGACCGCTCAGAGGGACTCCCTGTTGTGGAAGCTCGCGGGGTTGCTGCGGGAGTCCGGGGATGTGGTCCTGTCTGGCTGTAGCACC
CTGAGCCTGCTGACTCCCACACTGCAACAGCTGAACCACGTATTTGAGCTGCACCTGGGGCCATGGGGCCCTGGCCAGACAGGCTTTGTG
GCTCTGCCCTCCCATCCTGCCGACTCCCCTGTTATTCTTCAGCTTCAGTTTCTCTTCGATGTGCTGCAGAAAACACTTTCACTCAAGCTG
GTCCATGTTGCTGGTCCTGGCCCCACAGGGCCCATCAAGATTTTCCCCTTCAAATCCCTTCGGCACCTGGAGCTCCGAGGTGTTCCCCTC
CACTGTCTGCATGGCCTCCGAGGCATCTACTCCCAGCTGGAGACCCTGATTTGCAGCAGGAGCCTCCAGGCATTAGAGGAGCTCCTCTCA
GCCTGCGGCGGCGACTTCTGCTCTGCCCTCCCTTGGCTGGCTCTGCTTTCTGCCAACTTCAGCTACAATGCACTGACCGCCTTAGACAGC
TCCCTGCGCCTCTTGTCAGCTCTGCGTTTCTTGAACCTAAGCCACAATCAAGTCCAGGACTGTCAGGGATTCCTGATGGATTTGTGTGAG
CTCCACCATCTGGACATCTCCTATAATCGCCTGCATTTGGTGCCAAGAATGGGACCCTCAGGGGCTGCTCTGGGGGTCCTGATACTGCGA
GGCAATGAGCTTCGGAGCCTGCATGGCCTAGAGCAGCTGAGGAATCTGCGGCACCTGGATTTGGCATACAACCTGCTGGAAGGACACCGG
GAGCTGTCACCACTGTGGCTGCTGGCTGAGCTCCGCAAGCTCTACCTGGAGGGGAACCCTCTTTGGTTCCACCCTGAGCACCGAGCAGCC
ACTGCCCAGTACTTGTCACCCCGGGCCAGGGATGCTGCTACTGGCTTCCTTCTCGATGGCAAGGTCTTGTCACTGACAGATTTTCAGACT
CACACATCCTTGGGGCTCAGCCCCATGGGCCCACCTTTGCCCTGGCCAGTGGGGAGTACTCCTGAAACCTCAGGTGGCCCTGACCTGAGT
GACAGCCTCTCCTCAGGGGGTGTTGTGACCCAGCCCCTGCTTCATAAGGTTAAGAGCCGAGTCCGTGTGAGGCGGGCAAGCATCTCTGAA
CCCAGTGATACGGACCCGGAGCCCCGAACTCTGAACCCCTCTCCGGCTGAGGAAGAGGAGAAGGAGGGGAAGGAGGAGAAGGAGGAGGGG
GAGATGGTGGAACAGGGAGAAGAGGAGGCAGGAGAGGAGGAAGAAGAGGAGCAGGACCAGAAGGAAGTGGAAGGACACAGGGAACCGGAA
GGCTGCGGATAAGCTCATCCAGAACCTGGATGCCAATCATGATGGGCGCATCAGCTTCGATGAGTACTGGACCTTGATAGGCGGCATCAC
CGGCCCCATCGCCAAACTCATCCATGAGCAGGAGCAGCAGAGCAGCAGCTAGAGACCCCTTTGGCCACACCTTCCAGGCACTGGCCTGAT
GCCCCGCCCTGGTGCTCTCCCCAGGCTCCCTCCTCAGCCTCCTGCCCACCCAGGGCCCTTTACTCTCTTCTCCCTCCAGACCTTCCTCTG
ACCCTTGCTGAACTGGGGTCCCTTTGTGAGTGTCTCAGTCTAGAGGTACCTCCCTCCCTGGGGGGTCTCAGCTCCTGGAGTCGCAGGCCC
TTGGGGCCCCTCTGTGAGATCTCAATGCTGTCTGGGGACCCTAAGAGTTTTCTCACCTGTTCAGTCTCATCTAACCTTCCAATGTCTGAT
GTTCCTGCCAAATTCCTGCCTGATTCTGGGTCCGTCCTGACCTCCAAAGGTCAGCTTGGTGCTTGAGGTCTCCCTGCTCTTGGTGGCAGT
GGTAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCAGAGACCTCTCCACTTTCCCTTAGCCCCTCTGCTGGGTAGAGAGGCACTTT
CAGGGACTTCCCTCCAGCTGCCTCTTCATCTGGGAATGAGCTAAGCAAGGCTGAGCCTCCTCCTGTTGCTTGAAATAATGATGATATAAA
GGCTGGATTTGGAGTTTGTATCCCCTGGTCCCTCTGGGATGCTCATTAAAACCTTCCCACTCCTTGGAAAAGGCAGTCATTGTCCTGGTG
GAAAACTTCTACAAATATGTGTCTAAGTACAGCCTGGTCAAGAACAAGATCAGCAAGAGCAGCTTCCGCGAGATGCTCCAGAAAGAGCTG

>In-frame_ENST00000456909_ENST00000368704_TCGA-BH-A0DZ-01A_STK11IP_chr2_220473038_+_S100A16_chr1_153580599_length(amino acids)=453AA_start in transcript=90_stop in transcript=1451
MTTAQRDSLLWKLAGLLRESGDVVLSGCSTLSLLTPTLQQLNHVFELHLGPWGPGQTGFVALPSHPADSPVILQLQFLFDVLQKTLSLKL
VHVAGPGPTGPIKIFPFKSLRHLELRGVPLHCLHGLRGIYSQLETLICSRSLQALEELLSACGGDFCSALPWLALLSANFSYNALTALDS
SLRLLSALRFLNLSHNQVQDCQGFLMDLCELHHLDISYNRLHLVPRMGPSGAALGVLILRGNELRSLHGLEQLRNLRHLDLAYNLLEGHR
ELSPLWLLAELRKLYLEGNPLWFHPEHRAATAQYLSPRARDAATGFLLDGKVLSLTDFQTHTSLGLSPMGPPLPWPVGSTPETSGGPDLS
DSLSSGGVVTQPLLHKVKSRVRVRRASISEPSDTDPEPRTLNPSPAEEEEKEGKEEKEEGEMVEQGEEEAGEEEEEEQDQKEVEGHREPE

--------------------------------------------------------------
>In-frame_ENST00000456909_ENST00000368706_TCGA-BH-A0DZ-01A_STK11IP_chr2_220473038_+_S100A16_chr1_153580599_length(transcript)=2355nt_BP=1423nt
TCCTTTCCATCATTGATAGGCGCCGGGCAGCTGAGCTGGTAGGAGGACCAGACGGGGAGGTTCGGCTCCGCCCCCCAGCGTCCCGTGGCC
ATGACGACCGCTCAGAGGGACTCCCTGTTGTGGAAGCTCGCGGGGTTGCTGCGGGAGTCCGGGGATGTGGTCCTGTCTGGCTGTAGCACC
CTGAGCCTGCTGACTCCCACACTGCAACAGCTGAACCACGTATTTGAGCTGCACCTGGGGCCATGGGGCCCTGGCCAGACAGGCTTTGTG
GCTCTGCCCTCCCATCCTGCCGACTCCCCTGTTATTCTTCAGCTTCAGTTTCTCTTCGATGTGCTGCAGAAAACACTTTCACTCAAGCTG
GTCCATGTTGCTGGTCCTGGCCCCACAGGGCCCATCAAGATTTTCCCCTTCAAATCCCTTCGGCACCTGGAGCTCCGAGGTGTTCCCCTC
CACTGTCTGCATGGCCTCCGAGGCATCTACTCCCAGCTGGAGACCCTGATTTGCAGCAGGAGCCTCCAGGCATTAGAGGAGCTCCTCTCA
GCCTGCGGCGGCGACTTCTGCTCTGCCCTCCCTTGGCTGGCTCTGCTTTCTGCCAACTTCAGCTACAATGCACTGACCGCCTTAGACAGC
TCCCTGCGCCTCTTGTCAGCTCTGCGTTTCTTGAACCTAAGCCACAATCAAGTCCAGGACTGTCAGGGATTCCTGATGGATTTGTGTGAG
CTCCACCATCTGGACATCTCCTATAATCGCCTGCATTTGGTGCCAAGAATGGGACCCTCAGGGGCTGCTCTGGGGGTCCTGATACTGCGA
GGCAATGAGCTTCGGAGCCTGCATGGCCTAGAGCAGCTGAGGAATCTGCGGCACCTGGATTTGGCATACAACCTGCTGGAAGGACACCGG
GAGCTGTCACCACTGTGGCTGCTGGCTGAGCTCCGCAAGCTCTACCTGGAGGGGAACCCTCTTTGGTTCCACCCTGAGCACCGAGCAGCC
ACTGCCCAGTACTTGTCACCCCGGGCCAGGGATGCTGCTACTGGCTTCCTTCTCGATGGCAAGGTCTTGTCACTGACAGATTTTCAGACT
CACACATCCTTGGGGCTCAGCCCCATGGGCCCACCTTTGCCCTGGCCAGTGGGGAGTACTCCTGAAACCTCAGGTGGCCCTGACCTGAGT
GACAGCCTCTCCTCAGGGGGTGTTGTGACCCAGCCCCTGCTTCATAAGGTTAAGAGCCGAGTCCGTGTGAGGCGGGCAAGCATCTCTGAA
CCCAGTGATACGGACCCGGAGCCCCGAACTCTGAACCCCTCTCCGGCTGAGGAAGAGGAGAAGGAGGGGAAGGAGGAGAAGGAGGAGGGG
GAGATGGTGGAACAGGGAGAAGAGGAGGCAGGAGAGGAGGAAGAAGAGGAGCAGGACCAGAAGGAAGTGGAAGGACACAGGGAACCGGAA
GGCTGCGGATAAGCTCATCCAGAACCTGGATGCCAATCATGATGGGCGCATCAGCTTCGATGAGTACTGGACCTTGATAGGCGGCATCAC
CGGCCCCATCGCCAAACTCATCCATGAGCAGGAGCAGCAGAGCAGCAGCTAGAGACCCCTTTGGCCACACCTTCCAGGCACTGGCCTGAT
GCCCCGCCCTGGTGCTCTCCCCAGGCTCCCTCCTCAGCCTCCTGCCCACCCAGGGCCCTTTACTCTCTTCTCCCTCCAGACCTTCCTCTG
ACCCTTGCTGAACTGGGGTCCCTTTGTGAGTGTCTCAGTCTAGAGGTACCTCCCTCCCTGGGGGGTCTCAGCTCCTGGAGTCGCAGGCCC
TTGGGGCCCCTCTGTGAGATCTCAATGCTGTCTGGGGACCCTAAGAGTTTTCTCACCTGTTCAGTCTCATCTAACCTTCCAATGTCTGAT
GTTCCTGCCAAATTCCTGCCTGATTCTGGGTCCGTCCTGACCTCCAAAGGTCAGCTTGGTGCTTGAGGTCTCCCTGCTCTTGGTGGCAGT
GGTAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCAGAGACCTCTCCACTTTCCCTTAGCCCCTCTGCTGGGTAGAGAGGCACTTT
CAGGGACTTCCCTCCAGCTGCCTCTTCATCTGGGAATGAGCTAAGCAAGGCTGAGCCTCCTCCTGTTGCTTGAAATAATGATGATATAAA
GGCTGGATTTGGAGTTTGTATCCCCTGGTCCCTCTGGGATGCTCATTAAAACCTTCCCACTCCTTGGAAAAGGCAGTCATTGTCCTGGTG
GAAAACTTCTACAAATATGTGTCTAAGTACAGCCTGGTCAAGAACAAGATCAGCAAGAGCAGCTTCCGCGAGATGCTCCAGAAAGAGCTG

>In-frame_ENST00000456909_ENST00000368706_TCGA-BH-A0DZ-01A_STK11IP_chr2_220473038_+_S100A16_chr1_153580599_length(amino acids)=453AA_start in transcript=90_stop in transcript=1451
MTTAQRDSLLWKLAGLLRESGDVVLSGCSTLSLLTPTLQQLNHVFELHLGPWGPGQTGFVALPSHPADSPVILQLQFLFDVLQKTLSLKL
VHVAGPGPTGPIKIFPFKSLRHLELRGVPLHCLHGLRGIYSQLETLICSRSLQALEELLSACGGDFCSALPWLALLSANFSYNALTALDS
SLRLLSALRFLNLSHNQVQDCQGFLMDLCELHHLDISYNRLHLVPRMGPSGAALGVLILRGNELRSLHGLEQLRNLRHLDLAYNLLEGHR
ELSPLWLLAELRKLYLEGNPLWFHPEHRAATAQYLSPRARDAATGFLLDGKVLSLTDFQTHTSLGLSPMGPPLPWPVGSTPETSGGPDLS
DSLSSGGVVTQPLLHKVKSRVRVRRASISEPSDTDPEPRTLNPSPAEEEEKEGKEEKEEGEMVEQGEEEAGEEEEEEQDQKEVEGHREPE

--------------------------------------------------------------
>In-frame_ENST00000456909_ENST00000368703_TCGA-BH-A0DZ-01A_STK11IP_chr2_220473038_+_S100A16_chr1_153580599_length(transcript)=2266nt_BP=1423nt
TCCTTTCCATCATTGATAGGCGCCGGGCAGCTGAGCTGGTAGGAGGACCAGACGGGGAGGTTCGGCTCCGCCCCCCAGCGTCCCGTGGCC
ATGACGACCGCTCAGAGGGACTCCCTGTTGTGGAAGCTCGCGGGGTTGCTGCGGGAGTCCGGGGATGTGGTCCTGTCTGGCTGTAGCACC
CTGAGCCTGCTGACTCCCACACTGCAACAGCTGAACCACGTATTTGAGCTGCACCTGGGGCCATGGGGCCCTGGCCAGACAGGCTTTGTG
GCTCTGCCCTCCCATCCTGCCGACTCCCCTGTTATTCTTCAGCTTCAGTTTCTCTTCGATGTGCTGCAGAAAACACTTTCACTCAAGCTG
GTCCATGTTGCTGGTCCTGGCCCCACAGGGCCCATCAAGATTTTCCCCTTCAAATCCCTTCGGCACCTGGAGCTCCGAGGTGTTCCCCTC
CACTGTCTGCATGGCCTCCGAGGCATCTACTCCCAGCTGGAGACCCTGATTTGCAGCAGGAGCCTCCAGGCATTAGAGGAGCTCCTCTCA
GCCTGCGGCGGCGACTTCTGCTCTGCCCTCCCTTGGCTGGCTCTGCTTTCTGCCAACTTCAGCTACAATGCACTGACCGCCTTAGACAGC
TCCCTGCGCCTCTTGTCAGCTCTGCGTTTCTTGAACCTAAGCCACAATCAAGTCCAGGACTGTCAGGGATTCCTGATGGATTTGTGTGAG
CTCCACCATCTGGACATCTCCTATAATCGCCTGCATTTGGTGCCAAGAATGGGACCCTCAGGGGCTGCTCTGGGGGTCCTGATACTGCGA
GGCAATGAGCTTCGGAGCCTGCATGGCCTAGAGCAGCTGAGGAATCTGCGGCACCTGGATTTGGCATACAACCTGCTGGAAGGACACCGG
GAGCTGTCACCACTGTGGCTGCTGGCTGAGCTCCGCAAGCTCTACCTGGAGGGGAACCCTCTTTGGTTCCACCCTGAGCACCGAGCAGCC
ACTGCCCAGTACTTGTCACCCCGGGCCAGGGATGCTGCTACTGGCTTCCTTCTCGATGGCAAGGTCTTGTCACTGACAGATTTTCAGACT
CACACATCCTTGGGGCTCAGCCCCATGGGCCCACCTTTGCCCTGGCCAGTGGGGAGTACTCCTGAAACCTCAGGTGGCCCTGACCTGAGT
GACAGCCTCTCCTCAGGGGGTGTTGTGACCCAGCCCCTGCTTCATAAGGTTAAGAGCCGAGTCCGTGTGAGGCGGGCAAGCATCTCTGAA
CCCAGTGATACGGACCCGGAGCCCCGAACTCTGAACCCCTCTCCGGCTGAGGAAGAGGAGAAGGAGGGGAAGGAGGAGAAGGAGGAGGGG
GAGATGGTGGAACAGGGAGAAGAGGAGGCAGGAGAGGAGGAAGAAGAGGAGCAGGACCAGAAGGAAGTGGAAGGACACAGGGAACCGGAA
GGCTGCGGATAAGCTCATCCAGAACCTGGATGCCAATCATGATGGGCGCATCAGCTTCGATGAGTACTGGACCTTGATAGGCGGCATCAC
CGGCCCCATCGCCAAACTCATCCATGAGCAGGAGCAGCAGAGCAGCAGCTAGAGACCCCTTTGGCCACACCTTCCAGGCACTGGCCTGAT
GCCCCGCCCTGGTGCTCTCCCCAGGCTCCCTCCTCAGCCTCCTGCCCACCCAGGGCCCTTTACTCTCTTCTCCCTCCAGACCTTCCTCTG
ACCCTTGCTGAACTGGGGTCCCTTTGTGAGTGTCTCAGTCTAGAGGTACCTCCCTCCCTGGGGGGTCTCAGCTCCTGGAGTCGCAGGCCC
TTGGGGCCCCTCTGTGAGATCTCAATGCTGTCTGGGGACCCTAAGAGTTTTCTCACCTGTTCAGTCTCATCTAACCTTCCAATGTCTGAT
GTTCCTGCCAAATTCCTGCCTGATTCTGGGTCCGTCCTGACCTCCAAAGGTCAGCTTGGTGCTTGAGGTCTCCCTGCTCTTGGTGGCAGT
GGTAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCAGAGACCTCTCCACTTTCCCTTAGCCCCTCTGCTGGGTAGAGAGGCACTTT
CAGGGACTTCCCTCCAGCTGCCTCTTCATCTGGGAATGAGCTAAGCAAGGCTGAGCCTCCTCCTGTTGCTTAGGCAGTCATTGTCCTGGT
GGAAAACTTCTACAAATATGTGTCTAAGTACAGCCTGGTCAAGAACAAGATCAGCAAGAGCAGCTTCCGCGAGATGCTCCAGAAAGAGCT

>In-frame_ENST00000456909_ENST00000368703_TCGA-BH-A0DZ-01A_STK11IP_chr2_220473038_+_S100A16_chr1_153580599_length(amino acids)=453AA_start in transcript=90_stop in transcript=1451
MTTAQRDSLLWKLAGLLRESGDVVLSGCSTLSLLTPTLQQLNHVFELHLGPWGPGQTGFVALPSHPADSPVILQLQFLFDVLQKTLSLKL
VHVAGPGPTGPIKIFPFKSLRHLELRGVPLHCLHGLRGIYSQLETLICSRSLQALEELLSACGGDFCSALPWLALLSANFSYNALTALDS
SLRLLSALRFLNLSHNQVQDCQGFLMDLCELHHLDISYNRLHLVPRMGPSGAALGVLILRGNELRSLHGLEQLRNLRHLDLAYNLLEGHR
ELSPLWLLAELRKLYLEGNPLWFHPEHRAATAQYLSPRARDAATGFLLDGKVLSLTDFQTHTSLGLSPMGPPLPWPVGSTPETSGGPDLS
DSLSSGGVVTQPLLHKVKSRVRVRRASISEPSDTDPEPRTLNPSPAEEEEKEGKEEKEEGEMVEQGEEEAGEEEEEEQDQKEVEGHREPE

--------------------------------------------------------------
>In-frame_ENST00000456909_ENST00000368705_TCGA-BH-A0DZ-01A_STK11IP_chr2_220473038_+_S100A16_chr1_153580599_length(transcript)=1879nt_BP=1423nt
TCCTTTCCATCATTGATAGGCGCCGGGCAGCTGAGCTGGTAGGAGGACCAGACGGGGAGGTTCGGCTCCGCCCCCCAGCGTCCCGTGGCC
ATGACGACCGCTCAGAGGGACTCCCTGTTGTGGAAGCTCGCGGGGTTGCTGCGGGAGTCCGGGGATGTGGTCCTGTCTGGCTGTAGCACC
CTGAGCCTGCTGACTCCCACACTGCAACAGCTGAACCACGTATTTGAGCTGCACCTGGGGCCATGGGGCCCTGGCCAGACAGGCTTTGTG
GCTCTGCCCTCCCATCCTGCCGACTCCCCTGTTATTCTTCAGCTTCAGTTTCTCTTCGATGTGCTGCAGAAAACACTTTCACTCAAGCTG
GTCCATGTTGCTGGTCCTGGCCCCACAGGGCCCATCAAGATTTTCCCCTTCAAATCCCTTCGGCACCTGGAGCTCCGAGGTGTTCCCCTC
CACTGTCTGCATGGCCTCCGAGGCATCTACTCCCAGCTGGAGACCCTGATTTGCAGCAGGAGCCTCCAGGCATTAGAGGAGCTCCTCTCA
GCCTGCGGCGGCGACTTCTGCTCTGCCCTCCCTTGGCTGGCTCTGCTTTCTGCCAACTTCAGCTACAATGCACTGACCGCCTTAGACAGC
TCCCTGCGCCTCTTGTCAGCTCTGCGTTTCTTGAACCTAAGCCACAATCAAGTCCAGGACTGTCAGGGATTCCTGATGGATTTGTGTGAG
CTCCACCATCTGGACATCTCCTATAATCGCCTGCATTTGGTGCCAAGAATGGGACCCTCAGGGGCTGCTCTGGGGGTCCTGATACTGCGA
GGCAATGAGCTTCGGAGCCTGCATGGCCTAGAGCAGCTGAGGAATCTGCGGCACCTGGATTTGGCATACAACCTGCTGGAAGGACACCGG
GAGCTGTCACCACTGTGGCTGCTGGCTGAGCTCCGCAAGCTCTACCTGGAGGGGAACCCTCTTTGGTTCCACCCTGAGCACCGAGCAGCC
ACTGCCCAGTACTTGTCACCCCGGGCCAGGGATGCTGCTACTGGCTTCCTTCTCGATGGCAAGGTCTTGTCACTGACAGATTTTCAGACT
CACACATCCTTGGGGCTCAGCCCCATGGGCCCACCTTTGCCCTGGCCAGTGGGGAGTACTCCTGAAACCTCAGGTGGCCCTGACCTGAGT
GACAGCCTCTCCTCAGGGGGTGTTGTGACCCAGCCCCTGCTTCATAAGGTTAAGAGCCGAGTCCGTGTGAGGCGGGCAAGCATCTCTGAA
CCCAGTGATACGGACCCGGAGCCCCGAACTCTGAACCCCTCTCCGGCTGAGGAAGAGGAGAAGGAGGGGAAGGAGGAGAAGGAGGAGGGG
GAGATGGTGGAACAGGGAGAAGAGGAGGCAGGAGAGGAGGAAGAAGAGGAGCAGGACCAGAAGGAAGTGGAAGGACACAGGGAACCGGAA
GGCTGCGGATAAGCTCATCCAGAACCTGGATGCCAATCATGATGGGCGCATCAGCTTCGATGAGTACTGGACCTTGATAGGCGGCATCAC
CGGCCCCATCGCCAAACTCATCCATGAGCAGGAGCAGCAGAGCAGCAGCTAGAGACCCCTTTGGCCACACCTTCCAGGCACTGGCCTGAT
GCCCCGCCCTGGTGCTCTCCCCAGGCTCCCTCCTCAGCCTCCTGCCCACCCAGGGCCCTTTACTCTCTTCTCCCTCCAGACCTTCCTCTG
ACCCTTGCTGAACTGGGGTCCCTTTGTGAGTGTCTCAGTCTAGAAGGCAGTCATTGTCCTGGTGGAAAACTTCTACAAATATGTGTCTAA

>In-frame_ENST00000456909_ENST00000368705_TCGA-BH-A0DZ-01A_STK11IP_chr2_220473038_+_S100A16_chr1_153580599_length(amino acids)=453AA_start in transcript=90_stop in transcript=1451
MTTAQRDSLLWKLAGLLRESGDVVLSGCSTLSLLTPTLQQLNHVFELHLGPWGPGQTGFVALPSHPADSPVILQLQFLFDVLQKTLSLKL
VHVAGPGPTGPIKIFPFKSLRHLELRGVPLHCLHGLRGIYSQLETLICSRSLQALEELLSACGGDFCSALPWLALLSANFSYNALTALDS
SLRLLSALRFLNLSHNQVQDCQGFLMDLCELHHLDISYNRLHLVPRMGPSGAALGVLILRGNELRSLHGLEQLRNLRHLDLAYNLLEGHR
ELSPLWLLAELRKLYLEGNPLWFHPEHRAATAQYLSPRARDAATGFLLDGKVLSLTDFQTHTSLGLSPMGPPLPWPVGSTPETSGGPDLS
DSLSSGGVVTQPLLHKVKSRVRVRRASISEPSDTDPEPRTLNPSPAEEEEKEGKEEKEEGEMVEQGEEEAGEEEEEEQDQKEVEGHREPE

--------------------------------------------------------------
>In-frame_ENST00000295641_ENST00000368704_TCGA-BH-A0DZ-01A_STK11IP_chr2_220473038_+_S100A16_chr1_153580599_length(transcript)=2341nt_BP=1409nt
GATAGGCGCCGGGCAGCTGAGCTGGTAGGAGGACCAGACGGGGAGGTTCGGCTCCGCCCCCCAGCGTCCCGTGGCCATGACGACCGCTCA
GAGGGACTCCCTGTTGTGGAAGCTCGCGGGGTTGCTGCGGGAGTCCGGGGATGTGGTCCTGTCTGGCTGTAGCACCCTGAGCCTGCTGAC
TCCCACACTGCAACAGCTGAACCACGTATTTGAGCTGCACCTGGGGCCATGGGGCCCTGGCCAGACAGGCTTTGTGGCTCTGCCCTCCCA
TCCTGCCGACTCCCCTGTTATTCTTCAGCTTCAGTTTCTCTTCGATGTGCTGCAGAAAACACTTTCACTCAAGCTGGTCCATGTTGCTGG
TCCTGGCCCCACAGGGCCCATCAAGATTTTCCCCTTCAAATCCCTTCGGCACCTGGAGCTCCGAGGTGTTCCCCTCCACTGTCTGCATGG
CCTCCGAGGCATCTACTCCCAGCTGGAGACCCTGATTTGCAGCAGGAGCCTCCAGGCATTAGAGGAGCTCCTCTCAGCCTGCGGCGGCGA
CTTCTGCTCTGCCCTCCCTTGGCTGGCTCTGCTTTCTGCCAACTTCAGCTACAATGCACTGACCGCCTTAGACAGCTCCCTGCGCCTCTT
GTCAGCTCTGCGTTTCTTGAACCTAAGCCACAATCAAGTCCAGGACTGTCAGGGATTCCTGATGGATTTGTGTGAGCTCCACCATCTGGA
CATCTCCTATAATCGCCTGCATTTGGTGCCAAGAATGGGACCCTCAGGGGCTGCTCTGGGGGTCCTGATACTGCGAGGCAATGAGCTTCG
GAGCCTGCATGGCCTAGAGCAGCTGAGGAATCTGCGGCACCTGGATTTGGCATACAACCTGCTGGAAGGACACCGGGAGCTGTCACCACT
GTGGCTGCTGGCTGAGCTCCGCAAGCTCTACCTGGAGGGGAACCCTCTTTGGTTCCACCCTGAGCACCGAGCAGCCACTGCCCAGTACTT
GTCACCCCGGGCCAGGGATGCTGCTACTGGCTTCCTTCTCGATGGCAAGGTCTTGTCACTGACAGATTTTCAGACTCACACATCCTTGGG
GCTCAGCCCCATGGGCCCACCTTTGCCCTGGCCAGTGGGGAGTACTCCTGAAACCTCAGGTGGCCCTGACCTGAGTGACAGCCTCTCCTC
AGGGGGTGTTGTGACCCAGCCCCTGCTTCATAAGGTTAAGAGCCGAGTCCGTGTGAGGCGGGCAAGCATCTCTGAACCCAGTGATACGGA
CCCGGAGCCCCGAACTCTGAACCCCTCTCCGGCTGAGGAAGAGGAGAAGGAGGGGAAGGAGGAGAAGGAGGAGGGGGAGATGGTGGAACA
GGGAGAAGAGGAGGCAGGAGAGGAGGAAGAAGAGGAGCAGGACCAGAAGGAAGTGGAAGGACACAGGGAACCGGAAGGCTGCGGATAAGC
TCATCCAGAACCTGGATGCCAATCATGATGGGCGCATCAGCTTCGATGAGTACTGGACCTTGATAGGCGGCATCACCGGCCCCATCGCCA
AACTCATCCATGAGCAGGAGCAGCAGAGCAGCAGCTAGAGACCCCTTTGGCCACACCTTCCAGGCACTGGCCTGATGCCCCGCCCTGGTG
CTCTCCCCAGGCTCCCTCCTCAGCCTCCTGCCCACCCAGGGCCCTTTACTCTCTTCTCCCTCCAGACCTTCCTCTGACCCTTGCTGAACT
GGGGTCCCTTTGTGAGTGTCTCAGTCTAGAGGTACCTCCCTCCCTGGGGGGTCTCAGCTCCTGGAGTCGCAGGCCCTTGGGGCCCCTCTG
TGAGATCTCAATGCTGTCTGGGGACCCTAAGAGTTTTCTCACCTGTTCAGTCTCATCTAACCTTCCAATGTCTGATGTTCCTGCCAAATT
CCTGCCTGATTCTGGGTCCGTCCTGACCTCCAAAGGTCAGCTTGGTGCTTGAGGTCTCCCTGCTCTTGGTGGCAGTGGTAGCAGCAACAG
CAGCAGCAGCAGCAGCAGCAGCAGCAGAGACCTCTCCACTTTCCCTTAGCCCCTCTGCTGGGTAGAGAGGCACTTTCAGGGACTTCCCTC
CAGCTGCCTCTTCATCTGGGAATGAGCTAAGCAAGGCTGAGCCTCCTCCTGTTGCTTGAAATAATGATGATATAAAGGCTGGATTTGGAG
TTTGTATCCCCTGGTCCCTCTGGGATGCTCATTAAAACCTTCCCACTCCTTGGAAAAGGCAGTCATTGTCCTGGTGGAAAACTTCTACAA
ATATGTGTCTAAGTACAGCCTGGTCAAGAACAAGATCAGCAAGAGCAGCTTCCGCGAGATGCTCCAGAAAGAGCTGAACCACATGCTGTC

>In-frame_ENST00000295641_ENST00000368704_TCGA-BH-A0DZ-01A_STK11IP_chr2_220473038_+_S100A16_chr1_153580599_length(amino acids)=453AA_start in transcript=76_stop in transcript=1437
MTTAQRDSLLWKLAGLLRESGDVVLSGCSTLSLLTPTLQQLNHVFELHLGPWGPGQTGFVALPSHPADSPVILQLQFLFDVLQKTLSLKL
VHVAGPGPTGPIKIFPFKSLRHLELRGVPLHCLHGLRGIYSQLETLICSRSLQALEELLSACGGDFCSALPWLALLSANFSYNALTALDS
SLRLLSALRFLNLSHNQVQDCQGFLMDLCELHHLDISYNRLHLVPRMGPSGAALGVLILRGNELRSLHGLEQLRNLRHLDLAYNLLEGHR
ELSPLWLLAELRKLYLEGNPLWFHPEHRAATAQYLSPRARDAATGFLLDGKVLSLTDFQTHTSLGLSPMGPPLPWPVGSTPETSGGPDLS
DSLSSGGVVTQPLLHKVKSRVRVRRASISEPSDTDPEPRTLNPSPAEEEEKEGKEEKEEGEMVEQGEEEAGEEEEEEQDQKEVEGHREPE

--------------------------------------------------------------
>In-frame_ENST00000295641_ENST00000368706_TCGA-BH-A0DZ-01A_STK11IP_chr2_220473038_+_S100A16_chr1_153580599_length(transcript)=2341nt_BP=1409nt
GATAGGCGCCGGGCAGCTGAGCTGGTAGGAGGACCAGACGGGGAGGTTCGGCTCCGCCCCCCAGCGTCCCGTGGCCATGACGACCGCTCA
GAGGGACTCCCTGTTGTGGAAGCTCGCGGGGTTGCTGCGGGAGTCCGGGGATGTGGTCCTGTCTGGCTGTAGCACCCTGAGCCTGCTGAC
TCCCACACTGCAACAGCTGAACCACGTATTTGAGCTGCACCTGGGGCCATGGGGCCCTGGCCAGACAGGCTTTGTGGCTCTGCCCTCCCA
TCCTGCCGACTCCCCTGTTATTCTTCAGCTTCAGTTTCTCTTCGATGTGCTGCAGAAAACACTTTCACTCAAGCTGGTCCATGTTGCTGG
TCCTGGCCCCACAGGGCCCATCAAGATTTTCCCCTTCAAATCCCTTCGGCACCTGGAGCTCCGAGGTGTTCCCCTCCACTGTCTGCATGG
CCTCCGAGGCATCTACTCCCAGCTGGAGACCCTGATTTGCAGCAGGAGCCTCCAGGCATTAGAGGAGCTCCTCTCAGCCTGCGGCGGCGA
CTTCTGCTCTGCCCTCCCTTGGCTGGCTCTGCTTTCTGCCAACTTCAGCTACAATGCACTGACCGCCTTAGACAGCTCCCTGCGCCTCTT
GTCAGCTCTGCGTTTCTTGAACCTAAGCCACAATCAAGTCCAGGACTGTCAGGGATTCCTGATGGATTTGTGTGAGCTCCACCATCTGGA
CATCTCCTATAATCGCCTGCATTTGGTGCCAAGAATGGGACCCTCAGGGGCTGCTCTGGGGGTCCTGATACTGCGAGGCAATGAGCTTCG
GAGCCTGCATGGCCTAGAGCAGCTGAGGAATCTGCGGCACCTGGATTTGGCATACAACCTGCTGGAAGGACACCGGGAGCTGTCACCACT
GTGGCTGCTGGCTGAGCTCCGCAAGCTCTACCTGGAGGGGAACCCTCTTTGGTTCCACCCTGAGCACCGAGCAGCCACTGCCCAGTACTT
GTCACCCCGGGCCAGGGATGCTGCTACTGGCTTCCTTCTCGATGGCAAGGTCTTGTCACTGACAGATTTTCAGACTCACACATCCTTGGG
GCTCAGCCCCATGGGCCCACCTTTGCCCTGGCCAGTGGGGAGTACTCCTGAAACCTCAGGTGGCCCTGACCTGAGTGACAGCCTCTCCTC
AGGGGGTGTTGTGACCCAGCCCCTGCTTCATAAGGTTAAGAGCCGAGTCCGTGTGAGGCGGGCAAGCATCTCTGAACCCAGTGATACGGA
CCCGGAGCCCCGAACTCTGAACCCCTCTCCGGCTGAGGAAGAGGAGAAGGAGGGGAAGGAGGAGAAGGAGGAGGGGGAGATGGTGGAACA
GGGAGAAGAGGAGGCAGGAGAGGAGGAAGAAGAGGAGCAGGACCAGAAGGAAGTGGAAGGACACAGGGAACCGGAAGGCTGCGGATAAGC
TCATCCAGAACCTGGATGCCAATCATGATGGGCGCATCAGCTTCGATGAGTACTGGACCTTGATAGGCGGCATCACCGGCCCCATCGCCA
AACTCATCCATGAGCAGGAGCAGCAGAGCAGCAGCTAGAGACCCCTTTGGCCACACCTTCCAGGCACTGGCCTGATGCCCCGCCCTGGTG
CTCTCCCCAGGCTCCCTCCTCAGCCTCCTGCCCACCCAGGGCCCTTTACTCTCTTCTCCCTCCAGACCTTCCTCTGACCCTTGCTGAACT
GGGGTCCCTTTGTGAGTGTCTCAGTCTAGAGGTACCTCCCTCCCTGGGGGGTCTCAGCTCCTGGAGTCGCAGGCCCTTGGGGCCCCTCTG
TGAGATCTCAATGCTGTCTGGGGACCCTAAGAGTTTTCTCACCTGTTCAGTCTCATCTAACCTTCCAATGTCTGATGTTCCTGCCAAATT
CCTGCCTGATTCTGGGTCCGTCCTGACCTCCAAAGGTCAGCTTGGTGCTTGAGGTCTCCCTGCTCTTGGTGGCAGTGGTAGCAGCAACAG
CAGCAGCAGCAGCAGCAGCAGCAGCAGAGACCTCTCCACTTTCCCTTAGCCCCTCTGCTGGGTAGAGAGGCACTTTCAGGGACTTCCCTC
CAGCTGCCTCTTCATCTGGGAATGAGCTAAGCAAGGCTGAGCCTCCTCCTGTTGCTTGAAATAATGATGATATAAAGGCTGGATTTGGAG
TTTGTATCCCCTGGTCCCTCTGGGATGCTCATTAAAACCTTCCCACTCCTTGGAAAAGGCAGTCATTGTCCTGGTGGAAAACTTCTACAA
ATATGTGTCTAAGTACAGCCTGGTCAAGAACAAGATCAGCAAGAGCAGCTTCCGCGAGATGCTCCAGAAAGAGCTGAACCACATGCTGTC

>In-frame_ENST00000295641_ENST00000368706_TCGA-BH-A0DZ-01A_STK11IP_chr2_220473038_+_S100A16_chr1_153580599_length(amino acids)=453AA_start in transcript=76_stop in transcript=1437
MTTAQRDSLLWKLAGLLRESGDVVLSGCSTLSLLTPTLQQLNHVFELHLGPWGPGQTGFVALPSHPADSPVILQLQFLFDVLQKTLSLKL
VHVAGPGPTGPIKIFPFKSLRHLELRGVPLHCLHGLRGIYSQLETLICSRSLQALEELLSACGGDFCSALPWLALLSANFSYNALTALDS
SLRLLSALRFLNLSHNQVQDCQGFLMDLCELHHLDISYNRLHLVPRMGPSGAALGVLILRGNELRSLHGLEQLRNLRHLDLAYNLLEGHR
ELSPLWLLAELRKLYLEGNPLWFHPEHRAATAQYLSPRARDAATGFLLDGKVLSLTDFQTHTSLGLSPMGPPLPWPVGSTPETSGGPDLS
DSLSSGGVVTQPLLHKVKSRVRVRRASISEPSDTDPEPRTLNPSPAEEEEKEGKEEKEEGEMVEQGEEEAGEEEEEEQDQKEVEGHREPE

--------------------------------------------------------------
>In-frame_ENST00000295641_ENST00000368703_TCGA-BH-A0DZ-01A_STK11IP_chr2_220473038_+_S100A16_chr1_153580599_length(transcript)=2252nt_BP=1409nt
GATAGGCGCCGGGCAGCTGAGCTGGTAGGAGGACCAGACGGGGAGGTTCGGCTCCGCCCCCCAGCGTCCCGTGGCCATGACGACCGCTCA
GAGGGACTCCCTGTTGTGGAAGCTCGCGGGGTTGCTGCGGGAGTCCGGGGATGTGGTCCTGTCTGGCTGTAGCACCCTGAGCCTGCTGAC
TCCCACACTGCAACAGCTGAACCACGTATTTGAGCTGCACCTGGGGCCATGGGGCCCTGGCCAGACAGGCTTTGTGGCTCTGCCCTCCCA
TCCTGCCGACTCCCCTGTTATTCTTCAGCTTCAGTTTCTCTTCGATGTGCTGCAGAAAACACTTTCACTCAAGCTGGTCCATGTTGCTGG
TCCTGGCCCCACAGGGCCCATCAAGATTTTCCCCTTCAAATCCCTTCGGCACCTGGAGCTCCGAGGTGTTCCCCTCCACTGTCTGCATGG
CCTCCGAGGCATCTACTCCCAGCTGGAGACCCTGATTTGCAGCAGGAGCCTCCAGGCATTAGAGGAGCTCCTCTCAGCCTGCGGCGGCGA
CTTCTGCTCTGCCCTCCCTTGGCTGGCTCTGCTTTCTGCCAACTTCAGCTACAATGCACTGACCGCCTTAGACAGCTCCCTGCGCCTCTT
GTCAGCTCTGCGTTTCTTGAACCTAAGCCACAATCAAGTCCAGGACTGTCAGGGATTCCTGATGGATTTGTGTGAGCTCCACCATCTGGA
CATCTCCTATAATCGCCTGCATTTGGTGCCAAGAATGGGACCCTCAGGGGCTGCTCTGGGGGTCCTGATACTGCGAGGCAATGAGCTTCG
GAGCCTGCATGGCCTAGAGCAGCTGAGGAATCTGCGGCACCTGGATTTGGCATACAACCTGCTGGAAGGACACCGGGAGCTGTCACCACT
GTGGCTGCTGGCTGAGCTCCGCAAGCTCTACCTGGAGGGGAACCCTCTTTGGTTCCACCCTGAGCACCGAGCAGCCACTGCCCAGTACTT
GTCACCCCGGGCCAGGGATGCTGCTACTGGCTTCCTTCTCGATGGCAAGGTCTTGTCACTGACAGATTTTCAGACTCACACATCCTTGGG
GCTCAGCCCCATGGGCCCACCTTTGCCCTGGCCAGTGGGGAGTACTCCTGAAACCTCAGGTGGCCCTGACCTGAGTGACAGCCTCTCCTC
AGGGGGTGTTGTGACCCAGCCCCTGCTTCATAAGGTTAAGAGCCGAGTCCGTGTGAGGCGGGCAAGCATCTCTGAACCCAGTGATACGGA
CCCGGAGCCCCGAACTCTGAACCCCTCTCCGGCTGAGGAAGAGGAGAAGGAGGGGAAGGAGGAGAAGGAGGAGGGGGAGATGGTGGAACA
GGGAGAAGAGGAGGCAGGAGAGGAGGAAGAAGAGGAGCAGGACCAGAAGGAAGTGGAAGGACACAGGGAACCGGAAGGCTGCGGATAAGC
TCATCCAGAACCTGGATGCCAATCATGATGGGCGCATCAGCTTCGATGAGTACTGGACCTTGATAGGCGGCATCACCGGCCCCATCGCCA
AACTCATCCATGAGCAGGAGCAGCAGAGCAGCAGCTAGAGACCCCTTTGGCCACACCTTCCAGGCACTGGCCTGATGCCCCGCCCTGGTG
CTCTCCCCAGGCTCCCTCCTCAGCCTCCTGCCCACCCAGGGCCCTTTACTCTCTTCTCCCTCCAGACCTTCCTCTGACCCTTGCTGAACT
GGGGTCCCTTTGTGAGTGTCTCAGTCTAGAGGTACCTCCCTCCCTGGGGGGTCTCAGCTCCTGGAGTCGCAGGCCCTTGGGGCCCCTCTG
TGAGATCTCAATGCTGTCTGGGGACCCTAAGAGTTTTCTCACCTGTTCAGTCTCATCTAACCTTCCAATGTCTGATGTTCCTGCCAAATT
CCTGCCTGATTCTGGGTCCGTCCTGACCTCCAAAGGTCAGCTTGGTGCTTGAGGTCTCCCTGCTCTTGGTGGCAGTGGTAGCAGCAACAG
CAGCAGCAGCAGCAGCAGCAGCAGCAGAGACCTCTCCACTTTCCCTTAGCCCCTCTGCTGGGTAGAGAGGCACTTTCAGGGACTTCCCTC
CAGCTGCCTCTTCATCTGGGAATGAGCTAAGCAAGGCTGAGCCTCCTCCTGTTGCTTAGGCAGTCATTGTCCTGGTGGAAAACTTCTACA
AATATGTGTCTAAGTACAGCCTGGTCAAGAACAAGATCAGCAAGAGCAGCTTCCGCGAGATGCTCCAGAAAGAGCTGAACCACATGCTGT

>In-frame_ENST00000295641_ENST00000368703_TCGA-BH-A0DZ-01A_STK11IP_chr2_220473038_+_S100A16_chr1_153580599_length(amino acids)=453AA_start in transcript=76_stop in transcript=1437
MTTAQRDSLLWKLAGLLRESGDVVLSGCSTLSLLTPTLQQLNHVFELHLGPWGPGQTGFVALPSHPADSPVILQLQFLFDVLQKTLSLKL
VHVAGPGPTGPIKIFPFKSLRHLELRGVPLHCLHGLRGIYSQLETLICSRSLQALEELLSACGGDFCSALPWLALLSANFSYNALTALDS
SLRLLSALRFLNLSHNQVQDCQGFLMDLCELHHLDISYNRLHLVPRMGPSGAALGVLILRGNELRSLHGLEQLRNLRHLDLAYNLLEGHR
ELSPLWLLAELRKLYLEGNPLWFHPEHRAATAQYLSPRARDAATGFLLDGKVLSLTDFQTHTSLGLSPMGPPLPWPVGSTPETSGGPDLS
DSLSSGGVVTQPLLHKVKSRVRVRRASISEPSDTDPEPRTLNPSPAEEEEKEGKEEKEEGEMVEQGEEEAGEEEEEEQDQKEVEGHREPE

--------------------------------------------------------------
>In-frame_ENST00000295641_ENST00000368705_TCGA-BH-A0DZ-01A_STK11IP_chr2_220473038_+_S100A16_chr1_153580599_length(transcript)=1865nt_BP=1409nt
GATAGGCGCCGGGCAGCTGAGCTGGTAGGAGGACCAGACGGGGAGGTTCGGCTCCGCCCCCCAGCGTCCCGTGGCCATGACGACCGCTCA
GAGGGACTCCCTGTTGTGGAAGCTCGCGGGGTTGCTGCGGGAGTCCGGGGATGTGGTCCTGTCTGGCTGTAGCACCCTGAGCCTGCTGAC
TCCCACACTGCAACAGCTGAACCACGTATTTGAGCTGCACCTGGGGCCATGGGGCCCTGGCCAGACAGGCTTTGTGGCTCTGCCCTCCCA
TCCTGCCGACTCCCCTGTTATTCTTCAGCTTCAGTTTCTCTTCGATGTGCTGCAGAAAACACTTTCACTCAAGCTGGTCCATGTTGCTGG
TCCTGGCCCCACAGGGCCCATCAAGATTTTCCCCTTCAAATCCCTTCGGCACCTGGAGCTCCGAGGTGTTCCCCTCCACTGTCTGCATGG
CCTCCGAGGCATCTACTCCCAGCTGGAGACCCTGATTTGCAGCAGGAGCCTCCAGGCATTAGAGGAGCTCCTCTCAGCCTGCGGCGGCGA
CTTCTGCTCTGCCCTCCCTTGGCTGGCTCTGCTTTCTGCCAACTTCAGCTACAATGCACTGACCGCCTTAGACAGCTCCCTGCGCCTCTT
GTCAGCTCTGCGTTTCTTGAACCTAAGCCACAATCAAGTCCAGGACTGTCAGGGATTCCTGATGGATTTGTGTGAGCTCCACCATCTGGA
CATCTCCTATAATCGCCTGCATTTGGTGCCAAGAATGGGACCCTCAGGGGCTGCTCTGGGGGTCCTGATACTGCGAGGCAATGAGCTTCG
GAGCCTGCATGGCCTAGAGCAGCTGAGGAATCTGCGGCACCTGGATTTGGCATACAACCTGCTGGAAGGACACCGGGAGCTGTCACCACT
GTGGCTGCTGGCTGAGCTCCGCAAGCTCTACCTGGAGGGGAACCCTCTTTGGTTCCACCCTGAGCACCGAGCAGCCACTGCCCAGTACTT
GTCACCCCGGGCCAGGGATGCTGCTACTGGCTTCCTTCTCGATGGCAAGGTCTTGTCACTGACAGATTTTCAGACTCACACATCCTTGGG
GCTCAGCCCCATGGGCCCACCTTTGCCCTGGCCAGTGGGGAGTACTCCTGAAACCTCAGGTGGCCCTGACCTGAGTGACAGCCTCTCCTC
AGGGGGTGTTGTGACCCAGCCCCTGCTTCATAAGGTTAAGAGCCGAGTCCGTGTGAGGCGGGCAAGCATCTCTGAACCCAGTGATACGGA
CCCGGAGCCCCGAACTCTGAACCCCTCTCCGGCTGAGGAAGAGGAGAAGGAGGGGAAGGAGGAGAAGGAGGAGGGGGAGATGGTGGAACA
GGGAGAAGAGGAGGCAGGAGAGGAGGAAGAAGAGGAGCAGGACCAGAAGGAAGTGGAAGGACACAGGGAACCGGAAGGCTGCGGATAAGC
TCATCCAGAACCTGGATGCCAATCATGATGGGCGCATCAGCTTCGATGAGTACTGGACCTTGATAGGCGGCATCACCGGCCCCATCGCCA
AACTCATCCATGAGCAGGAGCAGCAGAGCAGCAGCTAGAGACCCCTTTGGCCACACCTTCCAGGCACTGGCCTGATGCCCCGCCCTGGTG
CTCTCCCCAGGCTCCCTCCTCAGCCTCCTGCCCACCCAGGGCCCTTTACTCTCTTCTCCCTCCAGACCTTCCTCTGACCCTTGCTGAACT
GGGGTCCCTTTGTGAGTGTCTCAGTCTAGAAGGCAGTCATTGTCCTGGTGGAAAACTTCTACAAATATGTGTCTAAGTACAGCCTGGTCA

>In-frame_ENST00000295641_ENST00000368705_TCGA-BH-A0DZ-01A_STK11IP_chr2_220473038_+_S100A16_chr1_153580599_length(amino acids)=453AA_start in transcript=76_stop in transcript=1437
MTTAQRDSLLWKLAGLLRESGDVVLSGCSTLSLLTPTLQQLNHVFELHLGPWGPGQTGFVALPSHPADSPVILQLQFLFDVLQKTLSLKL
VHVAGPGPTGPIKIFPFKSLRHLELRGVPLHCLHGLRGIYSQLETLICSRSLQALEELLSACGGDFCSALPWLALLSANFSYNALTALDS
SLRLLSALRFLNLSHNQVQDCQGFLMDLCELHHLDISYNRLHLVPRMGPSGAALGVLILRGNELRSLHGLEQLRNLRHLDLAYNLLEGHR
ELSPLWLLAELRKLYLEGNPLWFHPEHRAATAQYLSPRARDAATGFLLDGKVLSLTDFQTHTSLGLSPMGPPLPWPVGSTPETSGGPDLS
DSLSSGGVVTQPLLHKVKSRVRVRRASISEPSDTDPEPRTLNPSPAEEEEKEGKEEKEEGEMVEQGEEEAGEEEEEEQDQKEVEGHREPE

--------------------------------------------------------------

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Fusion Gene PPI Analysis for STK11IP-S100A16


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for STK11IP-S100A16


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for STK11IP-S100A16


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource