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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:STXBP4-NIPA2 (FusionGDB2 ID:87282)

Fusion Gene Summary for STXBP4-NIPA2

check button Fusion gene summary
Fusion gene informationFusion gene name: STXBP4-NIPA2
Fusion gene ID: 87282
HgeneTgene
Gene symbol

STXBP4

NIPA2

Gene ID

252983

81614

Gene namesyntaxin binding protein 4NIPA magnesium transporter 2
SynonymsSynipSLC57A2
Cytomap

17q22

15q11.2

Type of geneprotein-codingprotein-coding
Descriptionsyntaxin-binding protein 4STX4-interacting proteinsyntaxin 4 interacting proteinmagnesium transporter NIPA2non imprinted in Prader-Willi/Angelman syndrome 2non-imprinted in Prader-Willi/Angelman syndrome region protein 2
Modification date2020031320200313
UniProtAcc.

Q8N8Q9

Ensembl transtripts involved in fusion geneENST00000299341, ENST00000376352, 
ENST00000405898, ENST00000434978, 
ENST00000398391, 		ENST00000337451, 
ENST00000398014, ENST00000398013, 
ENST00000539711, ENST00000359727, 
ENST00000559571, 
Fusion gene scores* DoF score7 X 6 X 3=1262 X 2 X 2=8
# samples 62
** MAII scorelog2(6/126*10)=-1.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(2/8*10)=1.32192809488736
Context

PubMed: STXBP4 [Title/Abstract] AND NIPA2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSTXBP4(53158544)-NIPA2(23014528), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSTXBP4

GO:0006974

cellular response to DNA damage stimulus

19451233

HgeneSTXBP4

GO:0061178

regulation of insulin secretion involved in cellular response to glucose stimulus

12855681


check buttonFusion gene breakpoints across STXBP4 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across NIPA2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-BH-A1F2-01ASTXBP4chr17

53158544

+NIPA2chr15

23014528

+


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Fusion Gene ORF analysis for STXBP4-NIPA2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
intron-3CDSENST00000299341ENST00000337451STXBP4chr17

53158544

+NIPA2chr15

23014528

+
intron-3CDSENST00000299341ENST00000398014STXBP4chr17

53158544

+NIPA2chr15

23014528

+
intron-3CDSENST00000299341ENST00000398013STXBP4chr17

53158544

+NIPA2chr15

23014528

+
intron-3CDSENST00000299341ENST00000539711STXBP4chr17

53158544

+NIPA2chr15

23014528

+
intron-3CDSENST00000299341ENST00000359727STXBP4chr17

53158544

+NIPA2chr15

23014528

+
intron-intronENST00000299341ENST00000559571STXBP4chr17

53158544

+NIPA2chr15

23014528

+
In-frameENST00000376352ENST00000337451STXBP4chr17

53158544

+NIPA2chr15

23014528

+
In-frameENST00000376352ENST00000398014STXBP4chr17

53158544

+NIPA2chr15

23014528

+
In-frameENST00000376352ENST00000398013STXBP4chr17

53158544

+NIPA2chr15

23014528

+
In-frameENST00000376352ENST00000539711STXBP4chr17

53158544

+NIPA2chr15

23014528

+
In-frameENST00000376352ENST00000359727STXBP4chr17

53158544

+NIPA2chr15

23014528

+
5CDS-intronENST00000376352ENST00000559571STXBP4chr17

53158544

+NIPA2chr15

23014528

+
intron-3CDSENST00000405898ENST00000337451STXBP4chr17

53158544

+NIPA2chr15

23014528

+
intron-3CDSENST00000405898ENST00000398014STXBP4chr17

53158544

+NIPA2chr15

23014528

+
intron-3CDSENST00000405898ENST00000398013STXBP4chr17

53158544

+NIPA2chr15

23014528

+
intron-3CDSENST00000405898ENST00000539711STXBP4chr17

53158544

+NIPA2chr15

23014528

+
intron-3CDSENST00000405898ENST00000359727STXBP4chr17

53158544

+NIPA2chr15

23014528

+
intron-intronENST00000405898ENST00000559571STXBP4chr17

53158544

+NIPA2chr15

23014528

+
In-frameENST00000434978ENST00000337451STXBP4chr17

53158544

+NIPA2chr15

23014528

+
In-frameENST00000434978ENST00000398014STXBP4chr17

53158544

+NIPA2chr15

23014528

+
In-frameENST00000434978ENST00000398013STXBP4chr17

53158544

+NIPA2chr15

23014528

+
In-frameENST00000434978ENST00000539711STXBP4chr17

53158544

+NIPA2chr15

23014528

+
In-frameENST00000434978ENST00000359727STXBP4chr17

53158544

+NIPA2chr15

23014528

+
5CDS-intronENST00000434978ENST00000559571STXBP4chr17

53158544

+NIPA2chr15

23014528

+
intron-3CDSENST00000398391ENST00000337451STXBP4chr17

53158544

+NIPA2chr15

23014528

+
intron-3CDSENST00000398391ENST00000398014STXBP4chr17

53158544

+NIPA2chr15

23014528

+
intron-3CDSENST00000398391ENST00000398013STXBP4chr17

53158544

+NIPA2chr15

23014528

+
intron-3CDSENST00000398391ENST00000539711STXBP4chr17

53158544

+NIPA2chr15

23014528

+
intron-3CDSENST00000398391ENST00000359727STXBP4chr17

53158544

+NIPA2chr15

23014528

+
intron-intronENST00000398391ENST00000559571STXBP4chr17

53158544

+NIPA2chr15

23014528

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000376352STXBP4chr1753158544+ENST00000337451NIPA2chr1523014528+412016962072582791
ENST00000376352STXBP4chr1753158544+ENST00000398014NIPA2chr1523014528+412016962072582791
ENST00000376352STXBP4chr1753158544+ENST00000398013NIPA2chr1523014528+345216962072582791
ENST00000376352STXBP4chr1753158544+ENST00000539711NIPA2chr1523014528+265216962072582791
ENST00000376352STXBP4chr1753158544+ENST00000359727NIPA2chr1523014528+258316962072582791
ENST00000434978STXBP4chr1753158544+ENST00000337451NIPA2chr1523014528+404316191962505769
ENST00000434978STXBP4chr1753158544+ENST00000398014NIPA2chr1523014528+404316191962505769
ENST00000434978STXBP4chr1753158544+ENST00000398013NIPA2chr1523014528+337516191962505769
ENST00000434978STXBP4chr1753158544+ENST00000539711NIPA2chr1523014528+257516191962505769
ENST00000434978STXBP4chr1753158544+ENST00000359727NIPA2chr1523014528+250616191962505770

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000376352ENST00000337451STXBP4chr1753158544+NIPA2chr1523014528+0.0001200760.99987996
ENST00000376352ENST00000398014STXBP4chr1753158544+NIPA2chr1523014528+0.0001200760.99987996
ENST00000376352ENST00000398013STXBP4chr1753158544+NIPA2chr1523014528+0.0001323070.9998677
ENST00000376352ENST00000539711STXBP4chr1753158544+NIPA2chr1523014528+0.0001718960.9998281
ENST00000376352ENST00000359727STXBP4chr1753158544+NIPA2chr1523014528+0.0002042970.99979573
ENST00000434978ENST00000337451STXBP4chr1753158544+NIPA2chr1523014528+0.0001462540.99985373
ENST00000434978ENST00000398014STXBP4chr1753158544+NIPA2chr1523014528+0.0001462540.99985373
ENST00000434978ENST00000398013STXBP4chr1753158544+NIPA2chr1523014528+0.0001607080.9998393
ENST00000434978ENST00000539711STXBP4chr1753158544+NIPA2chr1523014528+0.0002082950.9997917
ENST00000434978ENST00000359727STXBP4chr1753158544+NIPA2chr1523014528+0.0002569090.99974304

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Fusion Genomic Features for STXBP4-NIPA2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for STXBP4-NIPA2


check button Go to

FGviewer for the breakpoints of chr17:53158544-chr15:23014528

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.NIPA2

Q8N8Q9

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Acts as a selective Mg(2+) transporter. {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSTXBP4chr17:53158544chr15:23014528ENST00000376352+1618291_417496.3333333333333554.0Coiled coilOntology_term=ECO:0000255
HgeneSTXBP4chr17:53158544chr15:23014528ENST00000376352+161819_105496.3333333333333554.0DomainPDZ
TgeneNIPA2chr17:53158544chr15:23014528ENST0000033745148100_10765.33333333333333361.0Topological domainCytoplasmic
TgeneNIPA2chr17:53158544chr15:23014528ENST0000033745148129_14965.33333333333333361.0Topological domainExtracellular
TgeneNIPA2chr17:53158544chr15:23014528ENST0000033745148171_17565.33333333333333361.0Topological domainCytoplasmic
TgeneNIPA2chr17:53158544chr15:23014528ENST0000033745148197_21565.33333333333333361.0Topological domainExtracellular
TgeneNIPA2chr17:53158544chr15:23014528ENST0000033745148237_24665.33333333333333361.0Topological domainCytoplasmic
TgeneNIPA2chr17:53158544chr15:23014528ENST0000033745148268_27865.33333333333333361.0Topological domainExtracellular
TgeneNIPA2chr17:53158544chr15:23014528ENST0000033745148300_36065.33333333333333361.0Topological domainCytoplasmic
TgeneNIPA2chr17:53158544chr15:23014528ENST000003374514878_7865.33333333333333361.0Topological domainExtracellular
TgeneNIPA2chr17:53158544chr15:23014528ENST0000035972726100_10746.333333333333336342.0Topological domainCytoplasmic
TgeneNIPA2chr17:53158544chr15:23014528ENST0000035972726129_14946.333333333333336342.0Topological domainExtracellular
TgeneNIPA2chr17:53158544chr15:23014528ENST0000035972726171_17546.333333333333336342.0Topological domainCytoplasmic
TgeneNIPA2chr17:53158544chr15:23014528ENST0000035972726197_21546.333333333333336342.0Topological domainExtracellular
TgeneNIPA2chr17:53158544chr15:23014528ENST0000035972726237_24646.333333333333336342.0Topological domainCytoplasmic
TgeneNIPA2chr17:53158544chr15:23014528ENST0000035972726268_27846.333333333333336342.0Topological domainExtracellular
TgeneNIPA2chr17:53158544chr15:23014528ENST0000035972726300_36046.333333333333336342.0Topological domainCytoplasmic
TgeneNIPA2chr17:53158544chr15:23014528ENST000003597272678_7846.333333333333336342.0Topological domainExtracellular
TgeneNIPA2chr17:53158544chr15:23014528ENST0000039801326100_10765.33333333333333361.0Topological domainCytoplasmic
TgeneNIPA2chr17:53158544chr15:23014528ENST0000039801326129_14965.33333333333333361.0Topological domainExtracellular
TgeneNIPA2chr17:53158544chr15:23014528ENST0000039801326171_17565.33333333333333361.0Topological domainCytoplasmic
TgeneNIPA2chr17:53158544chr15:23014528ENST0000039801326197_21565.33333333333333361.0Topological domainExtracellular
TgeneNIPA2chr17:53158544chr15:23014528ENST0000039801326237_24665.33333333333333361.0Topological domainCytoplasmic
TgeneNIPA2chr17:53158544chr15:23014528ENST0000039801326268_27865.33333333333333361.0Topological domainExtracellular
TgeneNIPA2chr17:53158544chr15:23014528ENST0000039801326300_36065.33333333333333361.0Topological domainCytoplasmic
TgeneNIPA2chr17:53158544chr15:23014528ENST000003980132678_7865.33333333333333361.0Topological domainExtracellular
TgeneNIPA2chr17:53158544chr15:23014528ENST0000039801437100_10765.33333333333333361.0Topological domainCytoplasmic
TgeneNIPA2chr17:53158544chr15:23014528ENST0000039801437129_14965.33333333333333361.0Topological domainExtracellular
TgeneNIPA2chr17:53158544chr15:23014528ENST0000039801437171_17565.33333333333333361.0Topological domainCytoplasmic
TgeneNIPA2chr17:53158544chr15:23014528ENST0000039801437197_21565.33333333333333361.0Topological domainExtracellular
TgeneNIPA2chr17:53158544chr15:23014528ENST0000039801437237_24665.33333333333333361.0Topological domainCytoplasmic
TgeneNIPA2chr17:53158544chr15:23014528ENST0000039801437268_27865.33333333333333361.0Topological domainExtracellular
TgeneNIPA2chr17:53158544chr15:23014528ENST0000039801437300_36065.33333333333333361.0Topological domainCytoplasmic
TgeneNIPA2chr17:53158544chr15:23014528ENST000003980143778_7865.33333333333333361.0Topological domainExtracellular
TgeneNIPA2chr17:53158544chr15:23014528ENST0000053971115100_10746.333333333333336342.0Topological domainCytoplasmic
TgeneNIPA2chr17:53158544chr15:23014528ENST0000053971115129_14946.333333333333336342.0Topological domainExtracellular
TgeneNIPA2chr17:53158544chr15:23014528ENST0000053971115171_17546.333333333333336342.0Topological domainCytoplasmic
TgeneNIPA2chr17:53158544chr15:23014528ENST0000053971115197_21546.333333333333336342.0Topological domainExtracellular
TgeneNIPA2chr17:53158544chr15:23014528ENST0000053971115237_24646.333333333333336342.0Topological domainCytoplasmic
TgeneNIPA2chr17:53158544chr15:23014528ENST0000053971115268_27846.333333333333336342.0Topological domainExtracellular
TgeneNIPA2chr17:53158544chr15:23014528ENST0000053971115300_36046.333333333333336342.0Topological domainCytoplasmic
TgeneNIPA2chr17:53158544chr15:23014528ENST000005397111578_7846.333333333333336342.0Topological domainExtracellular
TgeneNIPA2chr17:53158544chr15:23014528ENST0000033745148108_12865.33333333333333361.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST0000033745148150_17065.33333333333333361.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST0000033745148176_19665.33333333333333361.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST0000033745148216_23665.33333333333333361.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST0000033745148247_26765.33333333333333361.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST0000033745148279_29965.33333333333333361.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST000003374514879_9965.33333333333333361.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST0000035972726108_12846.333333333333336342.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST0000035972726150_17046.333333333333336342.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST0000035972726176_19646.333333333333336342.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST0000035972726216_23646.333333333333336342.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST0000035972726247_26746.333333333333336342.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST0000035972726279_29946.333333333333336342.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST000003597272657_7746.333333333333336342.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST000003597272679_9946.333333333333336342.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST0000039801326108_12865.33333333333333361.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST0000039801326150_17065.33333333333333361.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST0000039801326176_19665.33333333333333361.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST0000039801326216_23665.33333333333333361.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST0000039801326247_26765.33333333333333361.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST0000039801326279_29965.33333333333333361.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST000003980132679_9965.33333333333333361.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST0000039801437108_12865.33333333333333361.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST0000039801437150_17065.33333333333333361.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST0000039801437176_19665.33333333333333361.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST0000039801437216_23665.33333333333333361.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST0000039801437247_26765.33333333333333361.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST0000039801437279_29965.33333333333333361.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST000003980143779_9965.33333333333333361.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST0000053971115108_12846.333333333333336342.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST0000053971115150_17046.333333333333336342.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST0000053971115176_19646.333333333333336342.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST0000053971115216_23646.333333333333336342.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST0000053971115247_26746.333333333333336342.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST0000053971115279_29946.333333333333336342.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST000005397111557_7746.333333333333336342.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST000005397111579_9946.333333333333336342.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSTXBP4chr17:53158544chr15:23014528ENST00000299341+112291_4170246.0Coiled coilOntology_term=ECO:0000255
HgeneSTXBP4chr17:53158544chr15:23014528ENST00000398391+111291_4170246.0Coiled coilOntology_term=ECO:0000255
HgeneSTXBP4chr17:53158544chr15:23014528ENST00000299341+11219_1050246.0DomainPDZ
HgeneSTXBP4chr17:53158544chr15:23014528ENST00000299341+112496_5290246.0DomainWW
HgeneSTXBP4chr17:53158544chr15:23014528ENST00000376352+1618496_529496.3333333333333554.0DomainWW
HgeneSTXBP4chr17:53158544chr15:23014528ENST00000398391+11119_1050246.0DomainPDZ
HgeneSTXBP4chr17:53158544chr15:23014528ENST00000398391+111496_5290246.0DomainWW
TgeneNIPA2chr17:53158544chr15:23014528ENST00000337451481_965.33333333333333361.0Topological domainExtracellular
TgeneNIPA2chr17:53158544chr15:23014528ENST000003374514831_5665.33333333333333361.0Topological domainCytoplasmic
TgeneNIPA2chr17:53158544chr15:23014528ENST00000359727261_946.333333333333336342.0Topological domainExtracellular
TgeneNIPA2chr17:53158544chr15:23014528ENST000003597272631_5646.333333333333336342.0Topological domainCytoplasmic
TgeneNIPA2chr17:53158544chr15:23014528ENST00000398013261_965.33333333333333361.0Topological domainExtracellular
TgeneNIPA2chr17:53158544chr15:23014528ENST000003980132631_5665.33333333333333361.0Topological domainCytoplasmic
TgeneNIPA2chr17:53158544chr15:23014528ENST00000398014371_965.33333333333333361.0Topological domainExtracellular
TgeneNIPA2chr17:53158544chr15:23014528ENST000003980143731_5665.33333333333333361.0Topological domainCytoplasmic
TgeneNIPA2chr17:53158544chr15:23014528ENST00000539711151_946.333333333333336342.0Topological domainExtracellular
TgeneNIPA2chr17:53158544chr15:23014528ENST000005397111531_5646.333333333333336342.0Topological domainCytoplasmic
TgeneNIPA2chr17:53158544chr15:23014528ENST000003374514810_3065.33333333333333361.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST000003374514857_7765.33333333333333361.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST000003597272610_3046.333333333333336342.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST000003980132610_3065.33333333333333361.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST000003980132657_7765.33333333333333361.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST000003980143710_3065.33333333333333361.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST000003980143757_7765.33333333333333361.0TransmembraneHelical
TgeneNIPA2chr17:53158544chr15:23014528ENST000005397111510_3046.333333333333336342.0TransmembraneHelical


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Fusion Gene Sequence for STXBP4-NIPA2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000376352_ENST00000337451_TCGA-BH-A1F2-01A_STXBP4_chr17_53158544_+_NIPA2_chr15_23014528_length(transcript)=4120nt_BP=1696nt
AGGTGGCAGCGCTTGCAGTCGGGCTACGGAGGCCGGGTTGCCAGATTACGGGAAAGCCATTTAAGAAGTTCCTGGAATAATATTAGTCAG
AGTAATATAGGATCTGCAGGAAGTGTCTCAAGATAGTTGGAAAAGAAGAATTTCTAGACTCTTCATCAAGATCTTCATTTATACAGCTGT
TAAATCCAAGGCTACTTTGGTGAAAGCATGAATAAAAATACATCTACTGTAGTATCACCCAGTCTACTTGAAAAGGATCCTGCCTTTCAG
ATGATTACAATTGCCAAGGAAACAGGCCTTGGCCTGAAGGTACTAGGAGGAATTAACCGGAATGAAGGCCCATTGGTATATATTCAGGAA
ATTATTCCTGGAGGAGACTGTTATAAGGATGGTCGTTTGAAGCCAGGAGATCAACTTGTCTCAGTCAACAAGGAATCTATGATTGGTGTA
TCATTTGAAGAAGCAAAAAGCATAATTACCGGAGCCAAGTTGAGGTTAGAATCTGCTTGGGAGATAGCATTCATAAGACAAAAATCCGAC
AACATTCAGCCAGAAAATCTGTCATGTACATCACTTATAGAAGCTTCAGGAGAATATGGACCTCAAGCCTCAACATTAAGTCTTTTTTCT
TCTCCTCCTGAAATACTAATCCCAAAGACCTCATCCACTCCCAAAACAAATAATGACATTTTATCTTCTTGTGAGATAAAAACTGGATAC
AACAAAACAGTACAGATTCCAATTACTTCAGAAAACAGTACTGTGGGTTTGTCTAATACAGATGTTGCTTCTGCCTGGACTGAAAATTAT
GGGCTACAAGAAAAGATCTCCCTAAATCCCTCTGTTCGCTTTAAGGCAGAGAAACTGGAAATGGCTCTAAATTATCTTGGTATTCAGCCC
ACAAAGGAACAACACCAAGCCCTGAGACAGCAAGTACAAGCAGACTCAAAAGGGACAGTGTCTTTTGGAGATTTTGTCCAGGTTGCCAGA
AACTTGTTTTGCTTGCAGTTGGATGAAGTAAATGTTGGTGCACATGAAATTTCCAATATATTAGATTCACAGCTTCTTCCTTGTGATTCT
TCAGAAGCAGATGAAATGGAAAGGCTCAAGTGTGAAAGAGATGATGCCTTGAAAGAAGTAAATACACTTAAGGAAAAATTATTGGAATCA
GATAAGCAAAGGAAACAATTGACAGAAGAGCTCCAGAATGTGAAACAAGAAGCCAAAGCTGTAGTTGAAGAAACAAGAGCCCTGCGTAGT
CGGATTCATCTTGCTGAAGCTGCTCAGAGACAGGCACATGGAATGGAAATGGACTATGAAGAAGTGATCCGTCTGTTAGAGGCCAAGATT
ACAGAGCTAAAGGCTCAGCTTGCTGATTATTCTGACCAAAATAAAGAAAGTGTTCAGGATTTAAAAAAGAGAATCATGGTACTCGACTGC
CAATTACGAAAATCAGAAATGGCTCGAAAAACTTTTGAGGCATCCACTGAAAAGCTTCTTCATTTTGTAGAGGCTATTCAAGAAGTATTT
TCTGATAATTCTACTCCTTTATCAAATTTAAGTGAAAGAAGAGCTGTGTTAGCTTCTCAGACTTCCCTCACACCACTGGGAAGGAATGGA
CGTAGCATCCCAGCAACGCTGGCGCTTGAATCTAAGGAACTTGTTAAATCTGTTCGTGCCTTACTTGATATGGATTTGGGAGCTGGTGAG
GTGGCCAACTTCGCTGCGTATGCGTTTGCACCAGCCACTCTAGTGACTCCACTAGGAGCTCTCAGCGTGCTAGTAAGTGCCATTCTTTCT
TCATACTTTCTCAATGAAAGACTTAATCTTCATGGGAAAATTGGGTGTTTGCTAAGTATTCTAGGATCTACAGTTATGGTCATTCATGCT
CCAAAGGAAGAGGAGATTGAGACTTTAAATGAAATGTCTCACAAGCTAGGTGATCCAGGTTTTGTGGTCTTTGCAACCCTTGTGGTCATT
GTGGCCTTGATATTAATCTTCGTGGTGGGTCCTCGCCATGGACAGACAAACATTCTTGTGTACATAACAATCTGCTCTGTAATCGGCGCG
TTTTCAGTCTCCTGTGTGAAGGGCCTGGGCATTGCTATCAAGGAGCTGTTTGCAGGGAAGCCTGTGCTGCGGCATCCCCTGGCTTGGATT
CTGCTGCTGAGCCTCATCGTCTGTGTGAGCACACAGATTAATTACCTAAATAGGGCCCTGGATATATTCAACACTTCCATTGTGACTCCA
ATATATTATGTATTCTTTACAACATCAGTTTTAACTTGTTCAGCTATTCTTTTTAAGGAGTGGCAAGATATGCCTGTTGACGATGTCATT
GGTACTTTGAGTGGCTTCTTTACAATCATTGTGGGGATATTCTTGTTGCATGCCTTTAAAGACGTCAGCTTTAGTCTAGCAAGTCTGCCT
GTGTCTTTTCGAAAAGACGAGAAAGCAATGAATGGCAATCTCTCTAATATGTATGAAGTTCTTAATAATAATGAAGAAAGCTTAACCTGT
GGAATCGAACAACACACTGGTGAAAATGTCTCCCGAAGAAATGGAAATCTGACAGCTTTTTAAGAAAGGTGTAATTAAAGGTTAATCTGT
GATTGTTATGAAGTGAATTTGAATATCATCAGAATGTGTCTGAAAAAACATTGTCCTCAAATAATGTTCTTTAAAGGCAATCTTTTTAAA
GATTTCACTAATTTGGACCAAGAAATTACTTTTCTTGTATTTAAACAAACAATGGTAGCTCACTAAAATGACCTCAGCACATGACGATTT
CTATTAACATTTTATTGTTGTAGAAGTATTTTACATTTTCATCCCTTCTCCAAAAGCCGAATGCACTAATGACAGTTTTAAGTCTATGAA
AATGCTTTATTTTTTCATTGGTGATGAAAGTCTGAAATGTGCATTTGTCATCCCCACTCCATCAATCCCTGACCATGTAAGGCTTTTTTA
TTTTAAAAAAACAGAGTTATCCCAATACATTATCCTGTGATTTACCTTACCTACAAAAGTGGCTCCTGTTTGTTTGATGATGATTGGTTT
TATTTTTGAAATATTTATTAAGGGAAAACTAAGTTACTGAATGAAGGAACCTCTTTCTTACAAAACAAAAAAAAGGGCAGAAATCACCCC
AAGGAACGATTTCTCAGGTTGAGATGATCACCGTGAATCCGGCTTCCTCTGAGCATTCGATGGCCTTAGCACCTCATCAAGCCAGCACAT
CCTGCCTGCTGTTGCAGCCTGGCTGGGTTTATTCTTCAGTTACCCTAATCCCATGATGCCTGGAACCTTGATTACCGTTTTACATCAGCT
CTTGTACTTTTCAGTATATTTTCATAATGAGTTATATTGTCATTTAGACTTTGAACAGCTCTGGGAAATAGAAGACTAGGGTTGTTTCTT
AAATTTAGCTCATGTTATAATAAAAAGTTGAAATGAAGTTCTTATTCTAAAAGTCTGAATGCTTAGAACAAACTTAACATGTTTATAGAA
TATGGTCTCTTTGTACCAAGTACTTTGCTTAAGAGCTCCTTTGGGCCACTACATATTTTGGTTTCTAGAAAATGTTTGTTTATGAAGAAG
TCGATGGAAAACTGCAAACATATGCAGAAAAGGTAGAATAATAAAAAAGGTCTAATGAACTCCATTCAGCTTTGAACCTATCCACTCATA
ACCATTGACTGGCCTTTAAAAAAAAGTATTGGCAGAATTAATTTCCACCTAGGTGATGGGAAGAAAGTGTTCGCCTGTTCCAGCCTGTGG
CTCCTGCCTGGAGGTTACCCAGTGGTGCGCCAGCGCCAAGCCATCACTCCCCGAGGGCCTCCCCTGCCAATGGTGCTGGTATCCCATGCA
GCTCACCACTGGCTGCGTGGAAACTCCCTTTTTTCCAACTTTATTATTGGCCTTCTAAGGAGCTGTTTTAGATGTTTTTTCTAACTGCCT
CCTCCCATGCCATTTTAATACTACAGATGTACTACGTATCTGTTTATATACTGTACCTACATCTGTGCTTTGTACATAAAAGAACCAGTT

>In-frame_ENST00000376352_ENST00000337451_TCGA-BH-A1F2-01A_STXBP4_chr17_53158544_+_NIPA2_chr15_23014528_length(amino acids)=791AA_start in transcript=207_stop in transcript=2582
MNKNTSTVVSPSLLEKDPAFQMITIAKETGLGLKVLGGINRNEGPLVYIQEIIPGGDCYKDGRLKPGDQLVSVNKESMIGVSFEEAKSII
TGAKLRLESAWEIAFIRQKSDNIQPENLSCTSLIEASGEYGPQASTLSLFSSPPEILIPKTSSTPKTNNDILSSCEIKTGYNKTVQIPIT
SENSTVGLSNTDVASAWTENYGLQEKISLNPSVRFKAEKLEMALNYLGIQPTKEQHQALRQQVQADSKGTVSFGDFVQVARNLFCLQLDE
VNVGAHEISNILDSQLLPCDSSEADEMERLKCERDDALKEVNTLKEKLLESDKQRKQLTEELQNVKQEAKAVVEETRALRSRIHLAEAAQ
RQAHGMEMDYEEVIRLLEAKITELKAQLADYSDQNKESVQDLKKRIMVLDCQLRKSEMARKTFEASTEKLLHFVEAIQEVFSDNSTPLSN
LSERRAVLASQTSLTPLGRNGRSIPATLALESKELVKSVRALLDMDLGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLN
LHGKIGCLLSILGSTVMVIHAPKEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITICSVIGAFSVSCVKGL
GIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTI

--------------------------------------------------------------
>In-frame_ENST00000376352_ENST00000398014_TCGA-BH-A1F2-01A_STXBP4_chr17_53158544_+_NIPA2_chr15_23014528_length(transcript)=4120nt_BP=1696nt
AGGTGGCAGCGCTTGCAGTCGGGCTACGGAGGCCGGGTTGCCAGATTACGGGAAAGCCATTTAAGAAGTTCCTGGAATAATATTAGTCAG
AGTAATATAGGATCTGCAGGAAGTGTCTCAAGATAGTTGGAAAAGAAGAATTTCTAGACTCTTCATCAAGATCTTCATTTATACAGCTGT
TAAATCCAAGGCTACTTTGGTGAAAGCATGAATAAAAATACATCTACTGTAGTATCACCCAGTCTACTTGAAAAGGATCCTGCCTTTCAG
ATGATTACAATTGCCAAGGAAACAGGCCTTGGCCTGAAGGTACTAGGAGGAATTAACCGGAATGAAGGCCCATTGGTATATATTCAGGAA
ATTATTCCTGGAGGAGACTGTTATAAGGATGGTCGTTTGAAGCCAGGAGATCAACTTGTCTCAGTCAACAAGGAATCTATGATTGGTGTA
TCATTTGAAGAAGCAAAAAGCATAATTACCGGAGCCAAGTTGAGGTTAGAATCTGCTTGGGAGATAGCATTCATAAGACAAAAATCCGAC
AACATTCAGCCAGAAAATCTGTCATGTACATCACTTATAGAAGCTTCAGGAGAATATGGACCTCAAGCCTCAACATTAAGTCTTTTTTCT
TCTCCTCCTGAAATACTAATCCCAAAGACCTCATCCACTCCCAAAACAAATAATGACATTTTATCTTCTTGTGAGATAAAAACTGGATAC
AACAAAACAGTACAGATTCCAATTACTTCAGAAAACAGTACTGTGGGTTTGTCTAATACAGATGTTGCTTCTGCCTGGACTGAAAATTAT
GGGCTACAAGAAAAGATCTCCCTAAATCCCTCTGTTCGCTTTAAGGCAGAGAAACTGGAAATGGCTCTAAATTATCTTGGTATTCAGCCC
ACAAAGGAACAACACCAAGCCCTGAGACAGCAAGTACAAGCAGACTCAAAAGGGACAGTGTCTTTTGGAGATTTTGTCCAGGTTGCCAGA
AACTTGTTTTGCTTGCAGTTGGATGAAGTAAATGTTGGTGCACATGAAATTTCCAATATATTAGATTCACAGCTTCTTCCTTGTGATTCT
TCAGAAGCAGATGAAATGGAAAGGCTCAAGTGTGAAAGAGATGATGCCTTGAAAGAAGTAAATACACTTAAGGAAAAATTATTGGAATCA
GATAAGCAAAGGAAACAATTGACAGAAGAGCTCCAGAATGTGAAACAAGAAGCCAAAGCTGTAGTTGAAGAAACAAGAGCCCTGCGTAGT
CGGATTCATCTTGCTGAAGCTGCTCAGAGACAGGCACATGGAATGGAAATGGACTATGAAGAAGTGATCCGTCTGTTAGAGGCCAAGATT
ACAGAGCTAAAGGCTCAGCTTGCTGATTATTCTGACCAAAATAAAGAAAGTGTTCAGGATTTAAAAAAGAGAATCATGGTACTCGACTGC
CAATTACGAAAATCAGAAATGGCTCGAAAAACTTTTGAGGCATCCACTGAAAAGCTTCTTCATTTTGTAGAGGCTATTCAAGAAGTATTT
TCTGATAATTCTACTCCTTTATCAAATTTAAGTGAAAGAAGAGCTGTGTTAGCTTCTCAGACTTCCCTCACACCACTGGGAAGGAATGGA
CGTAGCATCCCAGCAACGCTGGCGCTTGAATCTAAGGAACTTGTTAAATCTGTTCGTGCCTTACTTGATATGGATTTGGGAGCTGGTGAG
GTGGCCAACTTCGCTGCGTATGCGTTTGCACCAGCCACTCTAGTGACTCCACTAGGAGCTCTCAGCGTGCTAGTAAGTGCCATTCTTTCT
TCATACTTTCTCAATGAAAGACTTAATCTTCATGGGAAAATTGGGTGTTTGCTAAGTATTCTAGGATCTACAGTTATGGTCATTCATGCT
CCAAAGGAAGAGGAGATTGAGACTTTAAATGAAATGTCTCACAAGCTAGGTGATCCAGGTTTTGTGGTCTTTGCAACCCTTGTGGTCATT
GTGGCCTTGATATTAATCTTCGTGGTGGGTCCTCGCCATGGACAGACAAACATTCTTGTGTACATAACAATCTGCTCTGTAATCGGCGCG
TTTTCAGTCTCCTGTGTGAAGGGCCTGGGCATTGCTATCAAGGAGCTGTTTGCAGGGAAGCCTGTGCTGCGGCATCCCCTGGCTTGGATT
CTGCTGCTGAGCCTCATCGTCTGTGTGAGCACACAGATTAATTACCTAAATAGGGCCCTGGATATATTCAACACTTCCATTGTGACTCCA
ATATATTATGTATTCTTTACAACATCAGTTTTAACTTGTTCAGCTATTCTTTTTAAGGAGTGGCAAGATATGCCTGTTGACGATGTCATT
GGTACTTTGAGTGGCTTCTTTACAATCATTGTGGGGATATTCTTGTTGCATGCCTTTAAAGACGTCAGCTTTAGTCTAGCAAGTCTGCCT
GTGTCTTTTCGAAAAGACGAGAAAGCAATGAATGGCAATCTCTCTAATATGTATGAAGTTCTTAATAATAATGAAGAAAGCTTAACCTGT
GGAATCGAACAACACACTGGTGAAAATGTCTCCCGAAGAAATGGAAATCTGACAGCTTTTTAAGAAAGGTGTAATTAAAGGTTAATCTGT
GATTGTTATGAAGTGAATTTGAATATCATCAGAATGTGTCTGAAAAAACATTGTCCTCAAATAATGTTCTTTAAAGGCAATCTTTTTAAA
GATTTCACTAATTTGGACCAAGAAATTACTTTTCTTGTATTTAAACAAACAATGGTAGCTCACTAAAATGACCTCAGCACATGACGATTT
CTATTAACATTTTATTGTTGTAGAAGTATTTTACATTTTCATCCCTTCTCCAAAAGCCGAATGCACTAATGACAGTTTTAAGTCTATGAA
AATGCTTTATTTTTTCATTGGTGATGAAAGTCTGAAATGTGCATTTGTCATCCCCACTCCATCAATCCCTGACCATGTAAGGCTTTTTTA
TTTTAAAAAAACAGAGTTATCCCAATACATTATCCTGTGATTTACCTTACCTACAAAAGTGGCTCCTGTTTGTTTGATGATGATTGGTTT
TATTTTTGAAATATTTATTAAGGGAAAACTAAGTTACTGAATGAAGGAACCTCTTTCTTACAAAACAAAAAAAAGGGCAGAAATCACCCC
AAGGAACGATTTCTCAGGTTGAGATGATCACCGTGAATCCGGCTTCCTCTGAGCATTCGATGGCCTTAGCACCTCATCAAGCCAGCACAT
CCTGCCTGCTGTTGCAGCCTGGCTGGGTTTATTCTTCAGTTACCCTAATCCCATGATGCCTGGAACCTTGATTACCGTTTTACATCAGCT
CTTGTACTTTTCAGTATATTTTCATAATGAGTTATATTGTCATTTAGACTTTGAACAGCTCTGGGAAATAGAAGACTAGGGTTGTTTCTT
AAATTTAGCTCATGTTATAATAAAAAGTTGAAATGAAGTTCTTATTCTAAAAGTCTGAATGCTTAGAACAAACTTAACATGTTTATAGAA
TATGGTCTCTTTGTACCAAGTACTTTGCTTAAGAGCTCCTTTGGGCCACTACATATTTTGGTTTCTAGAAAATGTTTGTTTATGAAGAAG
TCGATGGAAAACTGCAAACATATGCAGAAAAGGTAGAATAATAAAAAAGGTCTAATGAACTCCATTCAGCTTTGAACCTATCCACTCATA
ACCATTGACTGGCCTTTAAAAAAAAGTATTGGCAGAATTAATTTCCACCTAGGTGATGGGAAGAAAGTGTTCGCCTGTTCCAGCCTGTGG
CTCCTGCCTGGAGGTTACCCAGTGGTGCGCCAGCGCCAAGCCATCACTCCCCGAGGGCCTCCCCTGCCAATGGTGCTGGTATCCCATGCA
GCTCACCACTGGCTGCGTGGAAACTCCCTTTTTTCCAACTTTATTATTGGCCTTCTAAGGAGCTGTTTTAGATGTTTTTTCTAACTGCCT
CCTCCCATGCCATTTTAATACTACAGATGTACTACGTATCTGTTTATATACTGTACCTACATCTGTGCTTTGTACATAAAAGAACCAGTT

>In-frame_ENST00000376352_ENST00000398014_TCGA-BH-A1F2-01A_STXBP4_chr17_53158544_+_NIPA2_chr15_23014528_length(amino acids)=791AA_start in transcript=207_stop in transcript=2582
MNKNTSTVVSPSLLEKDPAFQMITIAKETGLGLKVLGGINRNEGPLVYIQEIIPGGDCYKDGRLKPGDQLVSVNKESMIGVSFEEAKSII
TGAKLRLESAWEIAFIRQKSDNIQPENLSCTSLIEASGEYGPQASTLSLFSSPPEILIPKTSSTPKTNNDILSSCEIKTGYNKTVQIPIT
SENSTVGLSNTDVASAWTENYGLQEKISLNPSVRFKAEKLEMALNYLGIQPTKEQHQALRQQVQADSKGTVSFGDFVQVARNLFCLQLDE
VNVGAHEISNILDSQLLPCDSSEADEMERLKCERDDALKEVNTLKEKLLESDKQRKQLTEELQNVKQEAKAVVEETRALRSRIHLAEAAQ
RQAHGMEMDYEEVIRLLEAKITELKAQLADYSDQNKESVQDLKKRIMVLDCQLRKSEMARKTFEASTEKLLHFVEAIQEVFSDNSTPLSN
LSERRAVLASQTSLTPLGRNGRSIPATLALESKELVKSVRALLDMDLGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLN
LHGKIGCLLSILGSTVMVIHAPKEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITICSVIGAFSVSCVKGL
GIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTI

--------------------------------------------------------------
>In-frame_ENST00000376352_ENST00000398013_TCGA-BH-A1F2-01A_STXBP4_chr17_53158544_+_NIPA2_chr15_23014528_length(transcript)=3452nt_BP=1696nt
AGGTGGCAGCGCTTGCAGTCGGGCTACGGAGGCCGGGTTGCCAGATTACGGGAAAGCCATTTAAGAAGTTCCTGGAATAATATTAGTCAG
AGTAATATAGGATCTGCAGGAAGTGTCTCAAGATAGTTGGAAAAGAAGAATTTCTAGACTCTTCATCAAGATCTTCATTTATACAGCTGT
TAAATCCAAGGCTACTTTGGTGAAAGCATGAATAAAAATACATCTACTGTAGTATCACCCAGTCTACTTGAAAAGGATCCTGCCTTTCAG
ATGATTACAATTGCCAAGGAAACAGGCCTTGGCCTGAAGGTACTAGGAGGAATTAACCGGAATGAAGGCCCATTGGTATATATTCAGGAA
ATTATTCCTGGAGGAGACTGTTATAAGGATGGTCGTTTGAAGCCAGGAGATCAACTTGTCTCAGTCAACAAGGAATCTATGATTGGTGTA
TCATTTGAAGAAGCAAAAAGCATAATTACCGGAGCCAAGTTGAGGTTAGAATCTGCTTGGGAGATAGCATTCATAAGACAAAAATCCGAC
AACATTCAGCCAGAAAATCTGTCATGTACATCACTTATAGAAGCTTCAGGAGAATATGGACCTCAAGCCTCAACATTAAGTCTTTTTTCT
TCTCCTCCTGAAATACTAATCCCAAAGACCTCATCCACTCCCAAAACAAATAATGACATTTTATCTTCTTGTGAGATAAAAACTGGATAC
AACAAAACAGTACAGATTCCAATTACTTCAGAAAACAGTACTGTGGGTTTGTCTAATACAGATGTTGCTTCTGCCTGGACTGAAAATTAT
GGGCTACAAGAAAAGATCTCCCTAAATCCCTCTGTTCGCTTTAAGGCAGAGAAACTGGAAATGGCTCTAAATTATCTTGGTATTCAGCCC
ACAAAGGAACAACACCAAGCCCTGAGACAGCAAGTACAAGCAGACTCAAAAGGGACAGTGTCTTTTGGAGATTTTGTCCAGGTTGCCAGA
AACTTGTTTTGCTTGCAGTTGGATGAAGTAAATGTTGGTGCACATGAAATTTCCAATATATTAGATTCACAGCTTCTTCCTTGTGATTCT
TCAGAAGCAGATGAAATGGAAAGGCTCAAGTGTGAAAGAGATGATGCCTTGAAAGAAGTAAATACACTTAAGGAAAAATTATTGGAATCA
GATAAGCAAAGGAAACAATTGACAGAAGAGCTCCAGAATGTGAAACAAGAAGCCAAAGCTGTAGTTGAAGAAACAAGAGCCCTGCGTAGT
CGGATTCATCTTGCTGAAGCTGCTCAGAGACAGGCACATGGAATGGAAATGGACTATGAAGAAGTGATCCGTCTGTTAGAGGCCAAGATT
ACAGAGCTAAAGGCTCAGCTTGCTGATTATTCTGACCAAAATAAAGAAAGTGTTCAGGATTTAAAAAAGAGAATCATGGTACTCGACTGC
CAATTACGAAAATCAGAAATGGCTCGAAAAACTTTTGAGGCATCCACTGAAAAGCTTCTTCATTTTGTAGAGGCTATTCAAGAAGTATTT
TCTGATAATTCTACTCCTTTATCAAATTTAAGTGAAAGAAGAGCTGTGTTAGCTTCTCAGACTTCCCTCACACCACTGGGAAGGAATGGA
CGTAGCATCCCAGCAACGCTGGCGCTTGAATCTAAGGAACTTGTTAAATCTGTTCGTGCCTTACTTGATATGGATTTGGGAGCTGGTGAG
GTGGCCAACTTCGCTGCGTATGCGTTTGCACCAGCCACTCTAGTGACTCCACTAGGAGCTCTCAGCGTGCTAGTAAGTGCCATTCTTTCT
TCATACTTTCTCAATGAAAGACTTAATCTTCATGGGAAAATTGGGTGTTTGCTAAGTATTCTAGGATCTACAGTTATGGTCATTCATGCT
CCAAAGGAAGAGGAGATTGAGACTTTAAATGAAATGTCTCACAAGCTAGGTGATCCAGGTTTTGTGGTCTTTGCAACCCTTGTGGTCATT
GTGGCCTTGATATTAATCTTCGTGGTGGGTCCTCGCCATGGACAGACAAACATTCTTGTGTACATAACAATCTGCTCTGTAATCGGCGCG
TTTTCAGTCTCCTGTGTGAAGGGCCTGGGCATTGCTATCAAGGAGCTGTTTGCAGGGAAGCCTGTGCTGCGGCATCCCCTGGCTTGGATT
CTGCTGCTGAGCCTCATCGTCTGTGTGAGCACACAGATTAATTACCTAAATAGGGCCCTGGATATATTCAACACTTCCATTGTGACTCCA
ATATATTATGTATTCTTTACAACATCAGTTTTAACTTGTTCAGCTATTCTTTTTAAGGAGTGGCAAGATATGCCTGTTGACGATGTCATT
GGTACTTTGAGTGGCTTCTTTACAATCATTGTGGGGATATTCTTGTTGCATGCCTTTAAAGACGTCAGCTTTAGTCTAGCAAGTCTGCCT
GTGTCTTTTCGAAAAGACGAGAAAGCAATGAATGGCAATCTCTCTAATATGTATGAAGTTCTTAATAATAATGAAGAAAGCTTAACCTGT
GGAATCGAACAACACACTGGTGAAAATGTCTCCCGAAGAAATGGAAATCTGACAGCTTTTTAAGAAAGGTGTAATTAAAGGTTAATCTGT
GATTGTTATGAAGTGAATTTGAATATCATCAGAATGTGTCTGAAAAAACATTGTCCTCAAATAATGTTCTTTAAAGGCAATCTTTTTAAA
GATTTCACTAATTTGGACCAAGAAATTACTTTTCTTGTATTTAAACAAACAATGGTAGCTCACTAAAATGACCTCAGCACATGACGATTT
CTATTAACATTTTATTGTTGTAGAAGTATTTTACATTTTCATCCCTTCTCCAAAAGCCGAATGCACTAATGACAGTTTTAAGTCTATGAA
AATGCTTTATTTTTTCATTGGTGATGAAAGTCTGAAATGTGCATTTGTCATCCCCACTCCATCAATCCCTGACCATGTAAGGCTTTTTTA
TTTTAAAAAAACAGAGTTATCCCAATACATTATCCTGTGATTTACCTTACCTACAAAAGTGGCTCCTGTTTGTTTGATGATGATTGGTTT
TATTTTTGAAATATTTATTAAGGGAAAACTAAGTTACTGAATGAAGGAACCTCTTTCTTACAAAACAAAAAAAAGGGCAGAAATCACCCC
AAGGAACGATTTCTCAGGTTGAGATGATCACCGTGAATCCGGCTTCCTCTGAGCATTCGATGGCCTTAGCACCTCATCAAGCCAGCACAT
CCTGCCTGCTGTTGCAGCCTGGCTGGGTTTATTCTTCAGTTACCCTAATCCCATGATGCCTGGAACCTTGATTACCGTTTTACATCAGCT
CTTGTACTTTTCAGTATATTTTCATAATGAGTTATATTGTCATTTAGACTTTGAACAGCTCTGGGAAATAGAAGACTAGGGTTGTTTCTT

>In-frame_ENST00000376352_ENST00000398013_TCGA-BH-A1F2-01A_STXBP4_chr17_53158544_+_NIPA2_chr15_23014528_length(amino acids)=791AA_start in transcript=207_stop in transcript=2582
MNKNTSTVVSPSLLEKDPAFQMITIAKETGLGLKVLGGINRNEGPLVYIQEIIPGGDCYKDGRLKPGDQLVSVNKESMIGVSFEEAKSII
TGAKLRLESAWEIAFIRQKSDNIQPENLSCTSLIEASGEYGPQASTLSLFSSPPEILIPKTSSTPKTNNDILSSCEIKTGYNKTVQIPIT
SENSTVGLSNTDVASAWTENYGLQEKISLNPSVRFKAEKLEMALNYLGIQPTKEQHQALRQQVQADSKGTVSFGDFVQVARNLFCLQLDE
VNVGAHEISNILDSQLLPCDSSEADEMERLKCERDDALKEVNTLKEKLLESDKQRKQLTEELQNVKQEAKAVVEETRALRSRIHLAEAAQ
RQAHGMEMDYEEVIRLLEAKITELKAQLADYSDQNKESVQDLKKRIMVLDCQLRKSEMARKTFEASTEKLLHFVEAIQEVFSDNSTPLSN
LSERRAVLASQTSLTPLGRNGRSIPATLALESKELVKSVRALLDMDLGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLN
LHGKIGCLLSILGSTVMVIHAPKEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITICSVIGAFSVSCVKGL
GIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTI

--------------------------------------------------------------
>In-frame_ENST00000376352_ENST00000539711_TCGA-BH-A1F2-01A_STXBP4_chr17_53158544_+_NIPA2_chr15_23014528_length(transcript)=2652nt_BP=1696nt
AGGTGGCAGCGCTTGCAGTCGGGCTACGGAGGCCGGGTTGCCAGATTACGGGAAAGCCATTTAAGAAGTTCCTGGAATAATATTAGTCAG
AGTAATATAGGATCTGCAGGAAGTGTCTCAAGATAGTTGGAAAAGAAGAATTTCTAGACTCTTCATCAAGATCTTCATTTATACAGCTGT
TAAATCCAAGGCTACTTTGGTGAAAGCATGAATAAAAATACATCTACTGTAGTATCACCCAGTCTACTTGAAAAGGATCCTGCCTTTCAG
ATGATTACAATTGCCAAGGAAACAGGCCTTGGCCTGAAGGTACTAGGAGGAATTAACCGGAATGAAGGCCCATTGGTATATATTCAGGAA
ATTATTCCTGGAGGAGACTGTTATAAGGATGGTCGTTTGAAGCCAGGAGATCAACTTGTCTCAGTCAACAAGGAATCTATGATTGGTGTA
TCATTTGAAGAAGCAAAAAGCATAATTACCGGAGCCAAGTTGAGGTTAGAATCTGCTTGGGAGATAGCATTCATAAGACAAAAATCCGAC
AACATTCAGCCAGAAAATCTGTCATGTACATCACTTATAGAAGCTTCAGGAGAATATGGACCTCAAGCCTCAACATTAAGTCTTTTTTCT
TCTCCTCCTGAAATACTAATCCCAAAGACCTCATCCACTCCCAAAACAAATAATGACATTTTATCTTCTTGTGAGATAAAAACTGGATAC
AACAAAACAGTACAGATTCCAATTACTTCAGAAAACAGTACTGTGGGTTTGTCTAATACAGATGTTGCTTCTGCCTGGACTGAAAATTAT
GGGCTACAAGAAAAGATCTCCCTAAATCCCTCTGTTCGCTTTAAGGCAGAGAAACTGGAAATGGCTCTAAATTATCTTGGTATTCAGCCC
ACAAAGGAACAACACCAAGCCCTGAGACAGCAAGTACAAGCAGACTCAAAAGGGACAGTGTCTTTTGGAGATTTTGTCCAGGTTGCCAGA
AACTTGTTTTGCTTGCAGTTGGATGAAGTAAATGTTGGTGCACATGAAATTTCCAATATATTAGATTCACAGCTTCTTCCTTGTGATTCT
TCAGAAGCAGATGAAATGGAAAGGCTCAAGTGTGAAAGAGATGATGCCTTGAAAGAAGTAAATACACTTAAGGAAAAATTATTGGAATCA
GATAAGCAAAGGAAACAATTGACAGAAGAGCTCCAGAATGTGAAACAAGAAGCCAAAGCTGTAGTTGAAGAAACAAGAGCCCTGCGTAGT
CGGATTCATCTTGCTGAAGCTGCTCAGAGACAGGCACATGGAATGGAAATGGACTATGAAGAAGTGATCCGTCTGTTAGAGGCCAAGATT
ACAGAGCTAAAGGCTCAGCTTGCTGATTATTCTGACCAAAATAAAGAAAGTGTTCAGGATTTAAAAAAGAGAATCATGGTACTCGACTGC
CAATTACGAAAATCAGAAATGGCTCGAAAAACTTTTGAGGCATCCACTGAAAAGCTTCTTCATTTTGTAGAGGCTATTCAAGAAGTATTT
TCTGATAATTCTACTCCTTTATCAAATTTAAGTGAAAGAAGAGCTGTGTTAGCTTCTCAGACTTCCCTCACACCACTGGGAAGGAATGGA
CGTAGCATCCCAGCAACGCTGGCGCTTGAATCTAAGGAACTTGTTAAATCTGTTCGTGCCTTACTTGATATGGATTTGGGAGCTGGTGAG
GTGGCCAACTTCGCTGCGTATGCGTTTGCACCAGCCACTCTAGTGACTCCACTAGGAGCTCTCAGCGTGCTAGTAAGTGCCATTCTTTCT
TCATACTTTCTCAATGAAAGACTTAATCTTCATGGGAAAATTGGGTGTTTGCTAAGTATTCTAGGATCTACAGTTATGGTCATTCATGCT
CCAAAGGAAGAGGAGATTGAGACTTTAAATGAAATGTCTCACAAGCTAGGTGATCCAGGTTTTGTGGTCTTTGCAACCCTTGTGGTCATT
GTGGCCTTGATATTAATCTTCGTGGTGGGTCCTCGCCATGGACAGACAAACATTCTTGTGTACATAACAATCTGCTCTGTAATCGGCGCG
TTTTCAGTCTCCTGTGTGAAGGGCCTGGGCATTGCTATCAAGGAGCTGTTTGCAGGGAAGCCTGTGCTGCGGCATCCCCTGGCTTGGATT
CTGCTGCTGAGCCTCATCGTCTGTGTGAGCACACAGATTAATTACCTAAATAGGGCCCTGGATATATTCAACACTTCCATTGTGACTCCA
ATATATTATGTATTCTTTACAACATCAGTTTTAACTTGTTCAGCTATTCTTTTTAAGGAGTGGCAAGATATGCCTGTTGACGATGTCATT
GGTACTTTGAGTGGCTTCTTTACAATCATTGTGGGGATATTCTTGTTGCATGCCTTTAAAGACGTCAGCTTTAGTCTAGCAAGTCTGCCT
GTGTCTTTTCGAAAAGACGAGAAAGCAATGAATGGCAATCTCTCTAATATGTATGAAGTTCTTAATAATAATGAAGAAAGCTTAACCTGT
GGAATCGAACAACACACTGGTGAAAATGTCTCCCGAAGAAATGGAAATCTGACAGCTTTTTAAGAAAGGTGTAATTAAAGGTTAATCTGT

>In-frame_ENST00000376352_ENST00000539711_TCGA-BH-A1F2-01A_STXBP4_chr17_53158544_+_NIPA2_chr15_23014528_length(amino acids)=791AA_start in transcript=207_stop in transcript=2582
MNKNTSTVVSPSLLEKDPAFQMITIAKETGLGLKVLGGINRNEGPLVYIQEIIPGGDCYKDGRLKPGDQLVSVNKESMIGVSFEEAKSII
TGAKLRLESAWEIAFIRQKSDNIQPENLSCTSLIEASGEYGPQASTLSLFSSPPEILIPKTSSTPKTNNDILSSCEIKTGYNKTVQIPIT
SENSTVGLSNTDVASAWTENYGLQEKISLNPSVRFKAEKLEMALNYLGIQPTKEQHQALRQQVQADSKGTVSFGDFVQVARNLFCLQLDE
VNVGAHEISNILDSQLLPCDSSEADEMERLKCERDDALKEVNTLKEKLLESDKQRKQLTEELQNVKQEAKAVVEETRALRSRIHLAEAAQ
RQAHGMEMDYEEVIRLLEAKITELKAQLADYSDQNKESVQDLKKRIMVLDCQLRKSEMARKTFEASTEKLLHFVEAIQEVFSDNSTPLSN
LSERRAVLASQTSLTPLGRNGRSIPATLALESKELVKSVRALLDMDLGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLN
LHGKIGCLLSILGSTVMVIHAPKEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITICSVIGAFSVSCVKGL
GIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTI

--------------------------------------------------------------
>In-frame_ENST00000376352_ENST00000359727_TCGA-BH-A1F2-01A_STXBP4_chr17_53158544_+_NIPA2_chr15_23014528_length(transcript)=2583nt_BP=1696nt
AGGTGGCAGCGCTTGCAGTCGGGCTACGGAGGCCGGGTTGCCAGATTACGGGAAAGCCATTTAAGAAGTTCCTGGAATAATATTAGTCAG
AGTAATATAGGATCTGCAGGAAGTGTCTCAAGATAGTTGGAAAAGAAGAATTTCTAGACTCTTCATCAAGATCTTCATTTATACAGCTGT
TAAATCCAAGGCTACTTTGGTGAAAGCATGAATAAAAATACATCTACTGTAGTATCACCCAGTCTACTTGAAAAGGATCCTGCCTTTCAG
ATGATTACAATTGCCAAGGAAACAGGCCTTGGCCTGAAGGTACTAGGAGGAATTAACCGGAATGAAGGCCCATTGGTATATATTCAGGAA
ATTATTCCTGGAGGAGACTGTTATAAGGATGGTCGTTTGAAGCCAGGAGATCAACTTGTCTCAGTCAACAAGGAATCTATGATTGGTGTA
TCATTTGAAGAAGCAAAAAGCATAATTACCGGAGCCAAGTTGAGGTTAGAATCTGCTTGGGAGATAGCATTCATAAGACAAAAATCCGAC
AACATTCAGCCAGAAAATCTGTCATGTACATCACTTATAGAAGCTTCAGGAGAATATGGACCTCAAGCCTCAACATTAAGTCTTTTTTCT
TCTCCTCCTGAAATACTAATCCCAAAGACCTCATCCACTCCCAAAACAAATAATGACATTTTATCTTCTTGTGAGATAAAAACTGGATAC
AACAAAACAGTACAGATTCCAATTACTTCAGAAAACAGTACTGTGGGTTTGTCTAATACAGATGTTGCTTCTGCCTGGACTGAAAATTAT
GGGCTACAAGAAAAGATCTCCCTAAATCCCTCTGTTCGCTTTAAGGCAGAGAAACTGGAAATGGCTCTAAATTATCTTGGTATTCAGCCC
ACAAAGGAACAACACCAAGCCCTGAGACAGCAAGTACAAGCAGACTCAAAAGGGACAGTGTCTTTTGGAGATTTTGTCCAGGTTGCCAGA
AACTTGTTTTGCTTGCAGTTGGATGAAGTAAATGTTGGTGCACATGAAATTTCCAATATATTAGATTCACAGCTTCTTCCTTGTGATTCT
TCAGAAGCAGATGAAATGGAAAGGCTCAAGTGTGAAAGAGATGATGCCTTGAAAGAAGTAAATACACTTAAGGAAAAATTATTGGAATCA
GATAAGCAAAGGAAACAATTGACAGAAGAGCTCCAGAATGTGAAACAAGAAGCCAAAGCTGTAGTTGAAGAAACAAGAGCCCTGCGTAGT
CGGATTCATCTTGCTGAAGCTGCTCAGAGACAGGCACATGGAATGGAAATGGACTATGAAGAAGTGATCCGTCTGTTAGAGGCCAAGATT
ACAGAGCTAAAGGCTCAGCTTGCTGATTATTCTGACCAAAATAAAGAAAGTGTTCAGGATTTAAAAAAGAGAATCATGGTACTCGACTGC
CAATTACGAAAATCAGAAATGGCTCGAAAAACTTTTGAGGCATCCACTGAAAAGCTTCTTCATTTTGTAGAGGCTATTCAAGAAGTATTT
TCTGATAATTCTACTCCTTTATCAAATTTAAGTGAAAGAAGAGCTGTGTTAGCTTCTCAGACTTCCCTCACACCACTGGGAAGGAATGGA
CGTAGCATCCCAGCAACGCTGGCGCTTGAATCTAAGGAACTTGTTAAATCTGTTCGTGCCTTACTTGATATGGATTTGGGAGCTGGTGAG
GTGGCCAACTTCGCTGCGTATGCGTTTGCACCAGCCACTCTAGTGACTCCACTAGGAGCTCTCAGCGTGCTAGTAAGTGCCATTCTTTCT
TCATACTTTCTCAATGAAAGACTTAATCTTCATGGGAAAATTGGGTGTTTGCTAAGTATTCTAGGATCTACAGTTATGGTCATTCATGCT
CCAAAGGAAGAGGAGATTGAGACTTTAAATGAAATGTCTCACAAGCTAGGTGATCCAGGTTTTGTGGTCTTTGCAACCCTTGTGGTCATT
GTGGCCTTGATATTAATCTTCGTGGTGGGTCCTCGCCATGGACAGACAAACATTCTTGTGTACATAACAATCTGCTCTGTAATCGGCGCG
TTTTCAGTCTCCTGTGTGAAGGGCCTGGGCATTGCTATCAAGGAGCTGTTTGCAGGGAAGCCTGTGCTGCGGCATCCCCTGGCTTGGATT
CTGCTGCTGAGCCTCATCGTCTGTGTGAGCACACAGATTAATTACCTAAATAGGGCCCTGGATATATTCAACACTTCCATTGTGACTCCA
ATATATTATGTATTCTTTACAACATCAGTTTTAACTTGTTCAGCTATTCTTTTTAAGGAGTGGCAAGATATGCCTGTTGACGATGTCATT
GGTACTTTGAGTGGCTTCTTTACAATCATTGTGGGGATATTCTTGTTGCATGCCTTTAAAGACGTCAGCTTTAGTCTAGCAAGTCTGCCT
GTGTCTTTTCGAAAAGACGAGAAAGCAATGAATGGCAATCTCTCTAATATGTATGAAGTTCTTAATAATAATGAAGAAAGCTTAACCTGT

>In-frame_ENST00000376352_ENST00000359727_TCGA-BH-A1F2-01A_STXBP4_chr17_53158544_+_NIPA2_chr15_23014528_length(amino acids)=791AA_start in transcript=207_stop in transcript=2582
MNKNTSTVVSPSLLEKDPAFQMITIAKETGLGLKVLGGINRNEGPLVYIQEIIPGGDCYKDGRLKPGDQLVSVNKESMIGVSFEEAKSII
TGAKLRLESAWEIAFIRQKSDNIQPENLSCTSLIEASGEYGPQASTLSLFSSPPEILIPKTSSTPKTNNDILSSCEIKTGYNKTVQIPIT
SENSTVGLSNTDVASAWTENYGLQEKISLNPSVRFKAEKLEMALNYLGIQPTKEQHQALRQQVQADSKGTVSFGDFVQVARNLFCLQLDE
VNVGAHEISNILDSQLLPCDSSEADEMERLKCERDDALKEVNTLKEKLLESDKQRKQLTEELQNVKQEAKAVVEETRALRSRIHLAEAAQ
RQAHGMEMDYEEVIRLLEAKITELKAQLADYSDQNKESVQDLKKRIMVLDCQLRKSEMARKTFEASTEKLLHFVEAIQEVFSDNSTPLSN
LSERRAVLASQTSLTPLGRNGRSIPATLALESKELVKSVRALLDMDLGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLN
LHGKIGCLLSILGSTVMVIHAPKEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITICSVIGAFSVSCVKGL
GIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTI

--------------------------------------------------------------
>In-frame_ENST00000434978_ENST00000337451_TCGA-BH-A1F2-01A_STXBP4_chr17_53158544_+_NIPA2_chr15_23014528_length(transcript)=4043nt_BP=1619nt
CTTGCAGTCGGGCTACGGAGGCCGGGTTGCCAGATTACGGGAAAGCCATTTAAGAAGTTCCTGGAATAATATTAGTCAGAGTAATATAGG
ATCTGCAGGAAGTGTCTCAAGATAGTTGGAAAAGAAGAATTTCTAGACTCTTCATCAAGATCTTCATTTATACAGCTGTTAAATCCAAGG
CTACTTTGGTGAAAGCATGAATAAAAATACATCTACTGTAGTATCACCCAGTCTACTTGAAAAGGATCCTGCCTTTCAGATGATTACAAT
TGCCAAGGAAACAGGCCTTGGCCTGAAGGTACTAGGAGGAATTAACCGGAATGAAGGCCCATTGGTATATATTCAGGAAATTATTCCTGG
AGGAGACTGTTATAAGGATGGTCGTTTGAAGCCAGGAGATCAACTTGTCTCAGTCAACAAGGAATCTATGATTGGTGTATCATTTGAAGA
AGCAAAAAGCATAATTACCGGAGCCAAGTTGAGGTTAGAATCTGCTTGGGAGATAGCATTCATAAGACAAAAATCCGACAACATTCAGCC
AGAAAATCTGTCATGTACATCACTTATAGAAGCTTCAGGAGAATATGGACCTCAAGCCTCAACATTAAGTCTTTTTTCTTCTCCTCCTGA
AATACTAATCCCAAAGACCTCATCCACTCCCAAAACAAATAATGACATTTTATCTTCTTGTGAGATAAAAACTGGATACAACAAAACAGT
ACAGATTCCAATTACTTCAGAAAACAGTACTGTGGGTTTGTCTAATACAGATGTTGCTTCTGCCTGGACTGAAAATTATGGGCTACAAGA
AAAGATCTCCCTAAATCCCTCTGTTCGCTTTAAGGCAGAGAAACTGGAAATGGCTCTAAATTATCTTGGTATTCAGCCCACAAAGGAACA
ACACCAAGCCCTGAGACAGCAAGTACAAGCAGACTCAAAAGGGACAGTGTCTTTTGGAGATTTTGTCCAGGTTGCCAGAAACTTGTTTTG
CTTGCAGTTGGATGAAGTAAATGTTGGTGCACATGAAATTTCCAATATATTAGATTCACAGCTTCTTCCTTGTGATTCTTCAGAAGCAGA
TGAAATGGAAAGGCTCAAGTGTGAAAGAGATGATGCCTTGAAAGAAGTAAATACACTTAAGGAAGCCAAAGCTGTAGTTGAAGAAACAAG
AGCCCTGCGTAGTCGGATTCATCTTGCTGAAGCTGCTCAGAGACAGGCACATGGAATGGAAATGGACTATGAAGAAGTGATCCGTCTGTT
AGAGGCCAAGATTACAGAGCTAAAGGCTCAGCTTGCTGATTATTCTGACCAAAATAAAGAAAGTGTTCAGGATTTAAAAAAGAGAATCAT
GGTACTCGACTGCCAATTACGAAAATCAGAAATGGCTCGAAAAACTTTTGAGGCATCCACTGAAAAGCTTCTTCATTTTGTAGAGGCTAT
TCAAGAAGTATTTTCTGATAATTCTACTCCTTTATCAAATTTAAGTGAAAGAAGAGCTGTGTTAGCTTCTCAGACTTCCCTCACACCACT
GGGAAGGAATGGACGTAGCATCCCAGCAACGCTGGCGCTTGAATCTAAGGAACTTGTTAAATCTGTTCGTGCCTTACTTGATATGGATTT
GGGAGCTGGTGAGGTGGCCAACTTCGCTGCGTATGCGTTTGCACCAGCCACTCTAGTGACTCCACTAGGAGCTCTCAGCGTGCTAGTAAG
TGCCATTCTTTCTTCATACTTTCTCAATGAAAGACTTAATCTTCATGGGAAAATTGGGTGTTTGCTAAGTATTCTAGGATCTACAGTTAT
GGTCATTCATGCTCCAAAGGAAGAGGAGATTGAGACTTTAAATGAAATGTCTCACAAGCTAGGTGATCCAGGTTTTGTGGTCTTTGCAAC
CCTTGTGGTCATTGTGGCCTTGATATTAATCTTCGTGGTGGGTCCTCGCCATGGACAGACAAACATTCTTGTGTACATAACAATCTGCTC
TGTAATCGGCGCGTTTTCAGTCTCCTGTGTGAAGGGCCTGGGCATTGCTATCAAGGAGCTGTTTGCAGGGAAGCCTGTGCTGCGGCATCC
CCTGGCTTGGATTCTGCTGCTGAGCCTCATCGTCTGTGTGAGCACACAGATTAATTACCTAAATAGGGCCCTGGATATATTCAACACTTC
CATTGTGACTCCAATATATTATGTATTCTTTACAACATCAGTTTTAACTTGTTCAGCTATTCTTTTTAAGGAGTGGCAAGATATGCCTGT
TGACGATGTCATTGGTACTTTGAGTGGCTTCTTTACAATCATTGTGGGGATATTCTTGTTGCATGCCTTTAAAGACGTCAGCTTTAGTCT
AGCAAGTCTGCCTGTGTCTTTTCGAAAAGACGAGAAAGCAATGAATGGCAATCTCTCTAATATGTATGAAGTTCTTAATAATAATGAAGA
AAGCTTAACCTGTGGAATCGAACAACACACTGGTGAAAATGTCTCCCGAAGAAATGGAAATCTGACAGCTTTTTAAGAAAGGTGTAATTA
AAGGTTAATCTGTGATTGTTATGAAGTGAATTTGAATATCATCAGAATGTGTCTGAAAAAACATTGTCCTCAAATAATGTTCTTTAAAGG
CAATCTTTTTAAAGATTTCACTAATTTGGACCAAGAAATTACTTTTCTTGTATTTAAACAAACAATGGTAGCTCACTAAAATGACCTCAG
CACATGACGATTTCTATTAACATTTTATTGTTGTAGAAGTATTTTACATTTTCATCCCTTCTCCAAAAGCCGAATGCACTAATGACAGTT
TTAAGTCTATGAAAATGCTTTATTTTTTCATTGGTGATGAAAGTCTGAAATGTGCATTTGTCATCCCCACTCCATCAATCCCTGACCATG
TAAGGCTTTTTTATTTTAAAAAAACAGAGTTATCCCAATACATTATCCTGTGATTTACCTTACCTACAAAAGTGGCTCCTGTTTGTTTGA
TGATGATTGGTTTTATTTTTGAAATATTTATTAAGGGAAAACTAAGTTACTGAATGAAGGAACCTCTTTCTTACAAAACAAAAAAAAGGG
CAGAAATCACCCCAAGGAACGATTTCTCAGGTTGAGATGATCACCGTGAATCCGGCTTCCTCTGAGCATTCGATGGCCTTAGCACCTCAT
CAAGCCAGCACATCCTGCCTGCTGTTGCAGCCTGGCTGGGTTTATTCTTCAGTTACCCTAATCCCATGATGCCTGGAACCTTGATTACCG
TTTTACATCAGCTCTTGTACTTTTCAGTATATTTTCATAATGAGTTATATTGTCATTTAGACTTTGAACAGCTCTGGGAAATAGAAGACT
AGGGTTGTTTCTTAAATTTAGCTCATGTTATAATAAAAAGTTGAAATGAAGTTCTTATTCTAAAAGTCTGAATGCTTAGAACAAACTTAA
CATGTTTATAGAATATGGTCTCTTTGTACCAAGTACTTTGCTTAAGAGCTCCTTTGGGCCACTACATATTTTGGTTTCTAGAAAATGTTT
GTTTATGAAGAAGTCGATGGAAAACTGCAAACATATGCAGAAAAGGTAGAATAATAAAAAAGGTCTAATGAACTCCATTCAGCTTTGAAC
CTATCCACTCATAACCATTGACTGGCCTTTAAAAAAAAGTATTGGCAGAATTAATTTCCACCTAGGTGATGGGAAGAAAGTGTTCGCCTG
TTCCAGCCTGTGGCTCCTGCCTGGAGGTTACCCAGTGGTGCGCCAGCGCCAAGCCATCACTCCCCGAGGGCCTCCCCTGCCAATGGTGCT
GGTATCCCATGCAGCTCACCACTGGCTGCGTGGAAACTCCCTTTTTTCCAACTTTATTATTGGCCTTCTAAGGAGCTGTTTTAGATGTTT
TTTCTAACTGCCTCCTCCCATGCCATTTTAATACTACAGATGTACTACGTATCTGTTTATATACTGTACCTACATCTGTGCTTTGTACAT

>In-frame_ENST00000434978_ENST00000337451_TCGA-BH-A1F2-01A_STXBP4_chr17_53158544_+_NIPA2_chr15_23014528_length(amino acids)=769AA_start in transcript=196_stop in transcript=2505
MNKNTSTVVSPSLLEKDPAFQMITIAKETGLGLKVLGGINRNEGPLVYIQEIIPGGDCYKDGRLKPGDQLVSVNKESMIGVSFEEAKSII
TGAKLRLESAWEIAFIRQKSDNIQPENLSCTSLIEASGEYGPQASTLSLFSSPPEILIPKTSSTPKTNNDILSSCEIKTGYNKTVQIPIT
SENSTVGLSNTDVASAWTENYGLQEKISLNPSVRFKAEKLEMALNYLGIQPTKEQHQALRQQVQADSKGTVSFGDFVQVARNLFCLQLDE
VNVGAHEISNILDSQLLPCDSSEADEMERLKCERDDALKEVNTLKEAKAVVEETRALRSRIHLAEAAQRQAHGMEMDYEEVIRLLEAKIT
ELKAQLADYSDQNKESVQDLKKRIMVLDCQLRKSEMARKTFEASTEKLLHFVEAIQEVFSDNSTPLSNLSERRAVLASQTSLTPLGRNGR
SIPATLALESKELVKSVRALLDMDLGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAP
KEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITICSVIGAFSVSCVKGLGIAIKELFAGKPVLRHPLAWIL
LLSLIVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLLHAFKDVSFSLASLPV

--------------------------------------------------------------
>In-frame_ENST00000434978_ENST00000398014_TCGA-BH-A1F2-01A_STXBP4_chr17_53158544_+_NIPA2_chr15_23014528_length(transcript)=4043nt_BP=1619nt
CTTGCAGTCGGGCTACGGAGGCCGGGTTGCCAGATTACGGGAAAGCCATTTAAGAAGTTCCTGGAATAATATTAGTCAGAGTAATATAGG
ATCTGCAGGAAGTGTCTCAAGATAGTTGGAAAAGAAGAATTTCTAGACTCTTCATCAAGATCTTCATTTATACAGCTGTTAAATCCAAGG
CTACTTTGGTGAAAGCATGAATAAAAATACATCTACTGTAGTATCACCCAGTCTACTTGAAAAGGATCCTGCCTTTCAGATGATTACAAT
TGCCAAGGAAACAGGCCTTGGCCTGAAGGTACTAGGAGGAATTAACCGGAATGAAGGCCCATTGGTATATATTCAGGAAATTATTCCTGG
AGGAGACTGTTATAAGGATGGTCGTTTGAAGCCAGGAGATCAACTTGTCTCAGTCAACAAGGAATCTATGATTGGTGTATCATTTGAAGA
AGCAAAAAGCATAATTACCGGAGCCAAGTTGAGGTTAGAATCTGCTTGGGAGATAGCATTCATAAGACAAAAATCCGACAACATTCAGCC
AGAAAATCTGTCATGTACATCACTTATAGAAGCTTCAGGAGAATATGGACCTCAAGCCTCAACATTAAGTCTTTTTTCTTCTCCTCCTGA
AATACTAATCCCAAAGACCTCATCCACTCCCAAAACAAATAATGACATTTTATCTTCTTGTGAGATAAAAACTGGATACAACAAAACAGT
ACAGATTCCAATTACTTCAGAAAACAGTACTGTGGGTTTGTCTAATACAGATGTTGCTTCTGCCTGGACTGAAAATTATGGGCTACAAGA
AAAGATCTCCCTAAATCCCTCTGTTCGCTTTAAGGCAGAGAAACTGGAAATGGCTCTAAATTATCTTGGTATTCAGCCCACAAAGGAACA
ACACCAAGCCCTGAGACAGCAAGTACAAGCAGACTCAAAAGGGACAGTGTCTTTTGGAGATTTTGTCCAGGTTGCCAGAAACTTGTTTTG
CTTGCAGTTGGATGAAGTAAATGTTGGTGCACATGAAATTTCCAATATATTAGATTCACAGCTTCTTCCTTGTGATTCTTCAGAAGCAGA
TGAAATGGAAAGGCTCAAGTGTGAAAGAGATGATGCCTTGAAAGAAGTAAATACACTTAAGGAAGCCAAAGCTGTAGTTGAAGAAACAAG
AGCCCTGCGTAGTCGGATTCATCTTGCTGAAGCTGCTCAGAGACAGGCACATGGAATGGAAATGGACTATGAAGAAGTGATCCGTCTGTT
AGAGGCCAAGATTACAGAGCTAAAGGCTCAGCTTGCTGATTATTCTGACCAAAATAAAGAAAGTGTTCAGGATTTAAAAAAGAGAATCAT
GGTACTCGACTGCCAATTACGAAAATCAGAAATGGCTCGAAAAACTTTTGAGGCATCCACTGAAAAGCTTCTTCATTTTGTAGAGGCTAT
TCAAGAAGTATTTTCTGATAATTCTACTCCTTTATCAAATTTAAGTGAAAGAAGAGCTGTGTTAGCTTCTCAGACTTCCCTCACACCACT
GGGAAGGAATGGACGTAGCATCCCAGCAACGCTGGCGCTTGAATCTAAGGAACTTGTTAAATCTGTTCGTGCCTTACTTGATATGGATTT
GGGAGCTGGTGAGGTGGCCAACTTCGCTGCGTATGCGTTTGCACCAGCCACTCTAGTGACTCCACTAGGAGCTCTCAGCGTGCTAGTAAG
TGCCATTCTTTCTTCATACTTTCTCAATGAAAGACTTAATCTTCATGGGAAAATTGGGTGTTTGCTAAGTATTCTAGGATCTACAGTTAT
GGTCATTCATGCTCCAAAGGAAGAGGAGATTGAGACTTTAAATGAAATGTCTCACAAGCTAGGTGATCCAGGTTTTGTGGTCTTTGCAAC
CCTTGTGGTCATTGTGGCCTTGATATTAATCTTCGTGGTGGGTCCTCGCCATGGACAGACAAACATTCTTGTGTACATAACAATCTGCTC
TGTAATCGGCGCGTTTTCAGTCTCCTGTGTGAAGGGCCTGGGCATTGCTATCAAGGAGCTGTTTGCAGGGAAGCCTGTGCTGCGGCATCC
CCTGGCTTGGATTCTGCTGCTGAGCCTCATCGTCTGTGTGAGCACACAGATTAATTACCTAAATAGGGCCCTGGATATATTCAACACTTC
CATTGTGACTCCAATATATTATGTATTCTTTACAACATCAGTTTTAACTTGTTCAGCTATTCTTTTTAAGGAGTGGCAAGATATGCCTGT
TGACGATGTCATTGGTACTTTGAGTGGCTTCTTTACAATCATTGTGGGGATATTCTTGTTGCATGCCTTTAAAGACGTCAGCTTTAGTCT
AGCAAGTCTGCCTGTGTCTTTTCGAAAAGACGAGAAAGCAATGAATGGCAATCTCTCTAATATGTATGAAGTTCTTAATAATAATGAAGA
AAGCTTAACCTGTGGAATCGAACAACACACTGGTGAAAATGTCTCCCGAAGAAATGGAAATCTGACAGCTTTTTAAGAAAGGTGTAATTA
AAGGTTAATCTGTGATTGTTATGAAGTGAATTTGAATATCATCAGAATGTGTCTGAAAAAACATTGTCCTCAAATAATGTTCTTTAAAGG
CAATCTTTTTAAAGATTTCACTAATTTGGACCAAGAAATTACTTTTCTTGTATTTAAACAAACAATGGTAGCTCACTAAAATGACCTCAG
CACATGACGATTTCTATTAACATTTTATTGTTGTAGAAGTATTTTACATTTTCATCCCTTCTCCAAAAGCCGAATGCACTAATGACAGTT
TTAAGTCTATGAAAATGCTTTATTTTTTCATTGGTGATGAAAGTCTGAAATGTGCATTTGTCATCCCCACTCCATCAATCCCTGACCATG
TAAGGCTTTTTTATTTTAAAAAAACAGAGTTATCCCAATACATTATCCTGTGATTTACCTTACCTACAAAAGTGGCTCCTGTTTGTTTGA
TGATGATTGGTTTTATTTTTGAAATATTTATTAAGGGAAAACTAAGTTACTGAATGAAGGAACCTCTTTCTTACAAAACAAAAAAAAGGG
CAGAAATCACCCCAAGGAACGATTTCTCAGGTTGAGATGATCACCGTGAATCCGGCTTCCTCTGAGCATTCGATGGCCTTAGCACCTCAT
CAAGCCAGCACATCCTGCCTGCTGTTGCAGCCTGGCTGGGTTTATTCTTCAGTTACCCTAATCCCATGATGCCTGGAACCTTGATTACCG
TTTTACATCAGCTCTTGTACTTTTCAGTATATTTTCATAATGAGTTATATTGTCATTTAGACTTTGAACAGCTCTGGGAAATAGAAGACT
AGGGTTGTTTCTTAAATTTAGCTCATGTTATAATAAAAAGTTGAAATGAAGTTCTTATTCTAAAAGTCTGAATGCTTAGAACAAACTTAA
CATGTTTATAGAATATGGTCTCTTTGTACCAAGTACTTTGCTTAAGAGCTCCTTTGGGCCACTACATATTTTGGTTTCTAGAAAATGTTT
GTTTATGAAGAAGTCGATGGAAAACTGCAAACATATGCAGAAAAGGTAGAATAATAAAAAAGGTCTAATGAACTCCATTCAGCTTTGAAC
CTATCCACTCATAACCATTGACTGGCCTTTAAAAAAAAGTATTGGCAGAATTAATTTCCACCTAGGTGATGGGAAGAAAGTGTTCGCCTG
TTCCAGCCTGTGGCTCCTGCCTGGAGGTTACCCAGTGGTGCGCCAGCGCCAAGCCATCACTCCCCGAGGGCCTCCCCTGCCAATGGTGCT
GGTATCCCATGCAGCTCACCACTGGCTGCGTGGAAACTCCCTTTTTTCCAACTTTATTATTGGCCTTCTAAGGAGCTGTTTTAGATGTTT
TTTCTAACTGCCTCCTCCCATGCCATTTTAATACTACAGATGTACTACGTATCTGTTTATATACTGTACCTACATCTGTGCTTTGTACAT

>In-frame_ENST00000434978_ENST00000398014_TCGA-BH-A1F2-01A_STXBP4_chr17_53158544_+_NIPA2_chr15_23014528_length(amino acids)=769AA_start in transcript=196_stop in transcript=2505
MNKNTSTVVSPSLLEKDPAFQMITIAKETGLGLKVLGGINRNEGPLVYIQEIIPGGDCYKDGRLKPGDQLVSVNKESMIGVSFEEAKSII
TGAKLRLESAWEIAFIRQKSDNIQPENLSCTSLIEASGEYGPQASTLSLFSSPPEILIPKTSSTPKTNNDILSSCEIKTGYNKTVQIPIT
SENSTVGLSNTDVASAWTENYGLQEKISLNPSVRFKAEKLEMALNYLGIQPTKEQHQALRQQVQADSKGTVSFGDFVQVARNLFCLQLDE
VNVGAHEISNILDSQLLPCDSSEADEMERLKCERDDALKEVNTLKEAKAVVEETRALRSRIHLAEAAQRQAHGMEMDYEEVIRLLEAKIT
ELKAQLADYSDQNKESVQDLKKRIMVLDCQLRKSEMARKTFEASTEKLLHFVEAIQEVFSDNSTPLSNLSERRAVLASQTSLTPLGRNGR
SIPATLALESKELVKSVRALLDMDLGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAP
KEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITICSVIGAFSVSCVKGLGIAIKELFAGKPVLRHPLAWIL
LLSLIVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLLHAFKDVSFSLASLPV

--------------------------------------------------------------
>In-frame_ENST00000434978_ENST00000398013_TCGA-BH-A1F2-01A_STXBP4_chr17_53158544_+_NIPA2_chr15_23014528_length(transcript)=3375nt_BP=1619nt
CTTGCAGTCGGGCTACGGAGGCCGGGTTGCCAGATTACGGGAAAGCCATTTAAGAAGTTCCTGGAATAATATTAGTCAGAGTAATATAGG
ATCTGCAGGAAGTGTCTCAAGATAGTTGGAAAAGAAGAATTTCTAGACTCTTCATCAAGATCTTCATTTATACAGCTGTTAAATCCAAGG
CTACTTTGGTGAAAGCATGAATAAAAATACATCTACTGTAGTATCACCCAGTCTACTTGAAAAGGATCCTGCCTTTCAGATGATTACAAT
TGCCAAGGAAACAGGCCTTGGCCTGAAGGTACTAGGAGGAATTAACCGGAATGAAGGCCCATTGGTATATATTCAGGAAATTATTCCTGG
AGGAGACTGTTATAAGGATGGTCGTTTGAAGCCAGGAGATCAACTTGTCTCAGTCAACAAGGAATCTATGATTGGTGTATCATTTGAAGA
AGCAAAAAGCATAATTACCGGAGCCAAGTTGAGGTTAGAATCTGCTTGGGAGATAGCATTCATAAGACAAAAATCCGACAACATTCAGCC
AGAAAATCTGTCATGTACATCACTTATAGAAGCTTCAGGAGAATATGGACCTCAAGCCTCAACATTAAGTCTTTTTTCTTCTCCTCCTGA
AATACTAATCCCAAAGACCTCATCCACTCCCAAAACAAATAATGACATTTTATCTTCTTGTGAGATAAAAACTGGATACAACAAAACAGT
ACAGATTCCAATTACTTCAGAAAACAGTACTGTGGGTTTGTCTAATACAGATGTTGCTTCTGCCTGGACTGAAAATTATGGGCTACAAGA
AAAGATCTCCCTAAATCCCTCTGTTCGCTTTAAGGCAGAGAAACTGGAAATGGCTCTAAATTATCTTGGTATTCAGCCCACAAAGGAACA
ACACCAAGCCCTGAGACAGCAAGTACAAGCAGACTCAAAAGGGACAGTGTCTTTTGGAGATTTTGTCCAGGTTGCCAGAAACTTGTTTTG
CTTGCAGTTGGATGAAGTAAATGTTGGTGCACATGAAATTTCCAATATATTAGATTCACAGCTTCTTCCTTGTGATTCTTCAGAAGCAGA
TGAAATGGAAAGGCTCAAGTGTGAAAGAGATGATGCCTTGAAAGAAGTAAATACACTTAAGGAAGCCAAAGCTGTAGTTGAAGAAACAAG
AGCCCTGCGTAGTCGGATTCATCTTGCTGAAGCTGCTCAGAGACAGGCACATGGAATGGAAATGGACTATGAAGAAGTGATCCGTCTGTT
AGAGGCCAAGATTACAGAGCTAAAGGCTCAGCTTGCTGATTATTCTGACCAAAATAAAGAAAGTGTTCAGGATTTAAAAAAGAGAATCAT
GGTACTCGACTGCCAATTACGAAAATCAGAAATGGCTCGAAAAACTTTTGAGGCATCCACTGAAAAGCTTCTTCATTTTGTAGAGGCTAT
TCAAGAAGTATTTTCTGATAATTCTACTCCTTTATCAAATTTAAGTGAAAGAAGAGCTGTGTTAGCTTCTCAGACTTCCCTCACACCACT
GGGAAGGAATGGACGTAGCATCCCAGCAACGCTGGCGCTTGAATCTAAGGAACTTGTTAAATCTGTTCGTGCCTTACTTGATATGGATTT
GGGAGCTGGTGAGGTGGCCAACTTCGCTGCGTATGCGTTTGCACCAGCCACTCTAGTGACTCCACTAGGAGCTCTCAGCGTGCTAGTAAG
TGCCATTCTTTCTTCATACTTTCTCAATGAAAGACTTAATCTTCATGGGAAAATTGGGTGTTTGCTAAGTATTCTAGGATCTACAGTTAT
GGTCATTCATGCTCCAAAGGAAGAGGAGATTGAGACTTTAAATGAAATGTCTCACAAGCTAGGTGATCCAGGTTTTGTGGTCTTTGCAAC
CCTTGTGGTCATTGTGGCCTTGATATTAATCTTCGTGGTGGGTCCTCGCCATGGACAGACAAACATTCTTGTGTACATAACAATCTGCTC
TGTAATCGGCGCGTTTTCAGTCTCCTGTGTGAAGGGCCTGGGCATTGCTATCAAGGAGCTGTTTGCAGGGAAGCCTGTGCTGCGGCATCC
CCTGGCTTGGATTCTGCTGCTGAGCCTCATCGTCTGTGTGAGCACACAGATTAATTACCTAAATAGGGCCCTGGATATATTCAACACTTC
CATTGTGACTCCAATATATTATGTATTCTTTACAACATCAGTTTTAACTTGTTCAGCTATTCTTTTTAAGGAGTGGCAAGATATGCCTGT
TGACGATGTCATTGGTACTTTGAGTGGCTTCTTTACAATCATTGTGGGGATATTCTTGTTGCATGCCTTTAAAGACGTCAGCTTTAGTCT
AGCAAGTCTGCCTGTGTCTTTTCGAAAAGACGAGAAAGCAATGAATGGCAATCTCTCTAATATGTATGAAGTTCTTAATAATAATGAAGA
AAGCTTAACCTGTGGAATCGAACAACACACTGGTGAAAATGTCTCCCGAAGAAATGGAAATCTGACAGCTTTTTAAGAAAGGTGTAATTA
AAGGTTAATCTGTGATTGTTATGAAGTGAATTTGAATATCATCAGAATGTGTCTGAAAAAACATTGTCCTCAAATAATGTTCTTTAAAGG
CAATCTTTTTAAAGATTTCACTAATTTGGACCAAGAAATTACTTTTCTTGTATTTAAACAAACAATGGTAGCTCACTAAAATGACCTCAG
CACATGACGATTTCTATTAACATTTTATTGTTGTAGAAGTATTTTACATTTTCATCCCTTCTCCAAAAGCCGAATGCACTAATGACAGTT
TTAAGTCTATGAAAATGCTTTATTTTTTCATTGGTGATGAAAGTCTGAAATGTGCATTTGTCATCCCCACTCCATCAATCCCTGACCATG
TAAGGCTTTTTTATTTTAAAAAAACAGAGTTATCCCAATACATTATCCTGTGATTTACCTTACCTACAAAAGTGGCTCCTGTTTGTTTGA
TGATGATTGGTTTTATTTTTGAAATATTTATTAAGGGAAAACTAAGTTACTGAATGAAGGAACCTCTTTCTTACAAAACAAAAAAAAGGG
CAGAAATCACCCCAAGGAACGATTTCTCAGGTTGAGATGATCACCGTGAATCCGGCTTCCTCTGAGCATTCGATGGCCTTAGCACCTCAT
CAAGCCAGCACATCCTGCCTGCTGTTGCAGCCTGGCTGGGTTTATTCTTCAGTTACCCTAATCCCATGATGCCTGGAACCTTGATTACCG
TTTTACATCAGCTCTTGTACTTTTCAGTATATTTTCATAATGAGTTATATTGTCATTTAGACTTTGAACAGCTCTGGGAAATAGAAGACT

>In-frame_ENST00000434978_ENST00000398013_TCGA-BH-A1F2-01A_STXBP4_chr17_53158544_+_NIPA2_chr15_23014528_length(amino acids)=769AA_start in transcript=196_stop in transcript=2505
MNKNTSTVVSPSLLEKDPAFQMITIAKETGLGLKVLGGINRNEGPLVYIQEIIPGGDCYKDGRLKPGDQLVSVNKESMIGVSFEEAKSII
TGAKLRLESAWEIAFIRQKSDNIQPENLSCTSLIEASGEYGPQASTLSLFSSPPEILIPKTSSTPKTNNDILSSCEIKTGYNKTVQIPIT
SENSTVGLSNTDVASAWTENYGLQEKISLNPSVRFKAEKLEMALNYLGIQPTKEQHQALRQQVQADSKGTVSFGDFVQVARNLFCLQLDE
VNVGAHEISNILDSQLLPCDSSEADEMERLKCERDDALKEVNTLKEAKAVVEETRALRSRIHLAEAAQRQAHGMEMDYEEVIRLLEAKIT
ELKAQLADYSDQNKESVQDLKKRIMVLDCQLRKSEMARKTFEASTEKLLHFVEAIQEVFSDNSTPLSNLSERRAVLASQTSLTPLGRNGR
SIPATLALESKELVKSVRALLDMDLGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAP
KEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITICSVIGAFSVSCVKGLGIAIKELFAGKPVLRHPLAWIL
LLSLIVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLLHAFKDVSFSLASLPV

--------------------------------------------------------------
>In-frame_ENST00000434978_ENST00000539711_TCGA-BH-A1F2-01A_STXBP4_chr17_53158544_+_NIPA2_chr15_23014528_length(transcript)=2575nt_BP=1619nt
CTTGCAGTCGGGCTACGGAGGCCGGGTTGCCAGATTACGGGAAAGCCATTTAAGAAGTTCCTGGAATAATATTAGTCAGAGTAATATAGG
ATCTGCAGGAAGTGTCTCAAGATAGTTGGAAAAGAAGAATTTCTAGACTCTTCATCAAGATCTTCATTTATACAGCTGTTAAATCCAAGG
CTACTTTGGTGAAAGCATGAATAAAAATACATCTACTGTAGTATCACCCAGTCTACTTGAAAAGGATCCTGCCTTTCAGATGATTACAAT
TGCCAAGGAAACAGGCCTTGGCCTGAAGGTACTAGGAGGAATTAACCGGAATGAAGGCCCATTGGTATATATTCAGGAAATTATTCCTGG
AGGAGACTGTTATAAGGATGGTCGTTTGAAGCCAGGAGATCAACTTGTCTCAGTCAACAAGGAATCTATGATTGGTGTATCATTTGAAGA
AGCAAAAAGCATAATTACCGGAGCCAAGTTGAGGTTAGAATCTGCTTGGGAGATAGCATTCATAAGACAAAAATCCGACAACATTCAGCC
AGAAAATCTGTCATGTACATCACTTATAGAAGCTTCAGGAGAATATGGACCTCAAGCCTCAACATTAAGTCTTTTTTCTTCTCCTCCTGA
AATACTAATCCCAAAGACCTCATCCACTCCCAAAACAAATAATGACATTTTATCTTCTTGTGAGATAAAAACTGGATACAACAAAACAGT
ACAGATTCCAATTACTTCAGAAAACAGTACTGTGGGTTTGTCTAATACAGATGTTGCTTCTGCCTGGACTGAAAATTATGGGCTACAAGA
AAAGATCTCCCTAAATCCCTCTGTTCGCTTTAAGGCAGAGAAACTGGAAATGGCTCTAAATTATCTTGGTATTCAGCCCACAAAGGAACA
ACACCAAGCCCTGAGACAGCAAGTACAAGCAGACTCAAAAGGGACAGTGTCTTTTGGAGATTTTGTCCAGGTTGCCAGAAACTTGTTTTG
CTTGCAGTTGGATGAAGTAAATGTTGGTGCACATGAAATTTCCAATATATTAGATTCACAGCTTCTTCCTTGTGATTCTTCAGAAGCAGA
TGAAATGGAAAGGCTCAAGTGTGAAAGAGATGATGCCTTGAAAGAAGTAAATACACTTAAGGAAGCCAAAGCTGTAGTTGAAGAAACAAG
AGCCCTGCGTAGTCGGATTCATCTTGCTGAAGCTGCTCAGAGACAGGCACATGGAATGGAAATGGACTATGAAGAAGTGATCCGTCTGTT
AGAGGCCAAGATTACAGAGCTAAAGGCTCAGCTTGCTGATTATTCTGACCAAAATAAAGAAAGTGTTCAGGATTTAAAAAAGAGAATCAT
GGTACTCGACTGCCAATTACGAAAATCAGAAATGGCTCGAAAAACTTTTGAGGCATCCACTGAAAAGCTTCTTCATTTTGTAGAGGCTAT
TCAAGAAGTATTTTCTGATAATTCTACTCCTTTATCAAATTTAAGTGAAAGAAGAGCTGTGTTAGCTTCTCAGACTTCCCTCACACCACT
GGGAAGGAATGGACGTAGCATCCCAGCAACGCTGGCGCTTGAATCTAAGGAACTTGTTAAATCTGTTCGTGCCTTACTTGATATGGATTT
GGGAGCTGGTGAGGTGGCCAACTTCGCTGCGTATGCGTTTGCACCAGCCACTCTAGTGACTCCACTAGGAGCTCTCAGCGTGCTAGTAAG
TGCCATTCTTTCTTCATACTTTCTCAATGAAAGACTTAATCTTCATGGGAAAATTGGGTGTTTGCTAAGTATTCTAGGATCTACAGTTAT
GGTCATTCATGCTCCAAAGGAAGAGGAGATTGAGACTTTAAATGAAATGTCTCACAAGCTAGGTGATCCAGGTTTTGTGGTCTTTGCAAC
CCTTGTGGTCATTGTGGCCTTGATATTAATCTTCGTGGTGGGTCCTCGCCATGGACAGACAAACATTCTTGTGTACATAACAATCTGCTC
TGTAATCGGCGCGTTTTCAGTCTCCTGTGTGAAGGGCCTGGGCATTGCTATCAAGGAGCTGTTTGCAGGGAAGCCTGTGCTGCGGCATCC
CCTGGCTTGGATTCTGCTGCTGAGCCTCATCGTCTGTGTGAGCACACAGATTAATTACCTAAATAGGGCCCTGGATATATTCAACACTTC
CATTGTGACTCCAATATATTATGTATTCTTTACAACATCAGTTTTAACTTGTTCAGCTATTCTTTTTAAGGAGTGGCAAGATATGCCTGT
TGACGATGTCATTGGTACTTTGAGTGGCTTCTTTACAATCATTGTGGGGATATTCTTGTTGCATGCCTTTAAAGACGTCAGCTTTAGTCT
AGCAAGTCTGCCTGTGTCTTTTCGAAAAGACGAGAAAGCAATGAATGGCAATCTCTCTAATATGTATGAAGTTCTTAATAATAATGAAGA
AAGCTTAACCTGTGGAATCGAACAACACACTGGTGAAAATGTCTCCCGAAGAAATGGAAATCTGACAGCTTTTTAAGAAAGGTGTAATTA

>In-frame_ENST00000434978_ENST00000539711_TCGA-BH-A1F2-01A_STXBP4_chr17_53158544_+_NIPA2_chr15_23014528_length(amino acids)=769AA_start in transcript=196_stop in transcript=2505
MNKNTSTVVSPSLLEKDPAFQMITIAKETGLGLKVLGGINRNEGPLVYIQEIIPGGDCYKDGRLKPGDQLVSVNKESMIGVSFEEAKSII
TGAKLRLESAWEIAFIRQKSDNIQPENLSCTSLIEASGEYGPQASTLSLFSSPPEILIPKTSSTPKTNNDILSSCEIKTGYNKTVQIPIT
SENSTVGLSNTDVASAWTENYGLQEKISLNPSVRFKAEKLEMALNYLGIQPTKEQHQALRQQVQADSKGTVSFGDFVQVARNLFCLQLDE
VNVGAHEISNILDSQLLPCDSSEADEMERLKCERDDALKEVNTLKEAKAVVEETRALRSRIHLAEAAQRQAHGMEMDYEEVIRLLEAKIT
ELKAQLADYSDQNKESVQDLKKRIMVLDCQLRKSEMARKTFEASTEKLLHFVEAIQEVFSDNSTPLSNLSERRAVLASQTSLTPLGRNGR
SIPATLALESKELVKSVRALLDMDLGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAP
KEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITICSVIGAFSVSCVKGLGIAIKELFAGKPVLRHPLAWIL
LLSLIVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLLHAFKDVSFSLASLPV

--------------------------------------------------------------
>In-frame_ENST00000434978_ENST00000359727_TCGA-BH-A1F2-01A_STXBP4_chr17_53158544_+_NIPA2_chr15_23014528_length(transcript)=2506nt_BP=1619nt
CTTGCAGTCGGGCTACGGAGGCCGGGTTGCCAGATTACGGGAAAGCCATTTAAGAAGTTCCTGGAATAATATTAGTCAGAGTAATATAGG
ATCTGCAGGAAGTGTCTCAAGATAGTTGGAAAAGAAGAATTTCTAGACTCTTCATCAAGATCTTCATTTATACAGCTGTTAAATCCAAGG
CTACTTTGGTGAAAGCATGAATAAAAATACATCTACTGTAGTATCACCCAGTCTACTTGAAAAGGATCCTGCCTTTCAGATGATTACAAT
TGCCAAGGAAACAGGCCTTGGCCTGAAGGTACTAGGAGGAATTAACCGGAATGAAGGCCCATTGGTATATATTCAGGAAATTATTCCTGG
AGGAGACTGTTATAAGGATGGTCGTTTGAAGCCAGGAGATCAACTTGTCTCAGTCAACAAGGAATCTATGATTGGTGTATCATTTGAAGA
AGCAAAAAGCATAATTACCGGAGCCAAGTTGAGGTTAGAATCTGCTTGGGAGATAGCATTCATAAGACAAAAATCCGACAACATTCAGCC
AGAAAATCTGTCATGTACATCACTTATAGAAGCTTCAGGAGAATATGGACCTCAAGCCTCAACATTAAGTCTTTTTTCTTCTCCTCCTGA
AATACTAATCCCAAAGACCTCATCCACTCCCAAAACAAATAATGACATTTTATCTTCTTGTGAGATAAAAACTGGATACAACAAAACAGT
ACAGATTCCAATTACTTCAGAAAACAGTACTGTGGGTTTGTCTAATACAGATGTTGCTTCTGCCTGGACTGAAAATTATGGGCTACAAGA
AAAGATCTCCCTAAATCCCTCTGTTCGCTTTAAGGCAGAGAAACTGGAAATGGCTCTAAATTATCTTGGTATTCAGCCCACAAAGGAACA
ACACCAAGCCCTGAGACAGCAAGTACAAGCAGACTCAAAAGGGACAGTGTCTTTTGGAGATTTTGTCCAGGTTGCCAGAAACTTGTTTTG
CTTGCAGTTGGATGAAGTAAATGTTGGTGCACATGAAATTTCCAATATATTAGATTCACAGCTTCTTCCTTGTGATTCTTCAGAAGCAGA
TGAAATGGAAAGGCTCAAGTGTGAAAGAGATGATGCCTTGAAAGAAGTAAATACACTTAAGGAAGCCAAAGCTGTAGTTGAAGAAACAAG
AGCCCTGCGTAGTCGGATTCATCTTGCTGAAGCTGCTCAGAGACAGGCACATGGAATGGAAATGGACTATGAAGAAGTGATCCGTCTGTT
AGAGGCCAAGATTACAGAGCTAAAGGCTCAGCTTGCTGATTATTCTGACCAAAATAAAGAAAGTGTTCAGGATTTAAAAAAGAGAATCAT
GGTACTCGACTGCCAATTACGAAAATCAGAAATGGCTCGAAAAACTTTTGAGGCATCCACTGAAAAGCTTCTTCATTTTGTAGAGGCTAT
TCAAGAAGTATTTTCTGATAATTCTACTCCTTTATCAAATTTAAGTGAAAGAAGAGCTGTGTTAGCTTCTCAGACTTCCCTCACACCACT
GGGAAGGAATGGACGTAGCATCCCAGCAACGCTGGCGCTTGAATCTAAGGAACTTGTTAAATCTGTTCGTGCCTTACTTGATATGGATTT
GGGAGCTGGTGAGGTGGCCAACTTCGCTGCGTATGCGTTTGCACCAGCCACTCTAGTGACTCCACTAGGAGCTCTCAGCGTGCTAGTAAG
TGCCATTCTTTCTTCATACTTTCTCAATGAAAGACTTAATCTTCATGGGAAAATTGGGTGTTTGCTAAGTATTCTAGGATCTACAGTTAT
GGTCATTCATGCTCCAAAGGAAGAGGAGATTGAGACTTTAAATGAAATGTCTCACAAGCTAGGTGATCCAGGTTTTGTGGTCTTTGCAAC
CCTTGTGGTCATTGTGGCCTTGATATTAATCTTCGTGGTGGGTCCTCGCCATGGACAGACAAACATTCTTGTGTACATAACAATCTGCTC
TGTAATCGGCGCGTTTTCAGTCTCCTGTGTGAAGGGCCTGGGCATTGCTATCAAGGAGCTGTTTGCAGGGAAGCCTGTGCTGCGGCATCC
CCTGGCTTGGATTCTGCTGCTGAGCCTCATCGTCTGTGTGAGCACACAGATTAATTACCTAAATAGGGCCCTGGATATATTCAACACTTC
CATTGTGACTCCAATATATTATGTATTCTTTACAACATCAGTTTTAACTTGTTCAGCTATTCTTTTTAAGGAGTGGCAAGATATGCCTGT
TGACGATGTCATTGGTACTTTGAGTGGCTTCTTTACAATCATTGTGGGGATATTCTTGTTGCATGCCTTTAAAGACGTCAGCTTTAGTCT
AGCAAGTCTGCCTGTGTCTTTTCGAAAAGACGAGAAAGCAATGAATGGCAATCTCTCTAATATGTATGAAGTTCTTAATAATAATGAAGA

>In-frame_ENST00000434978_ENST00000359727_TCGA-BH-A1F2-01A_STXBP4_chr17_53158544_+_NIPA2_chr15_23014528_length(amino acids)=770AA_start in transcript=196_stop in transcript=2505
MNKNTSTVVSPSLLEKDPAFQMITIAKETGLGLKVLGGINRNEGPLVYIQEIIPGGDCYKDGRLKPGDQLVSVNKESMIGVSFEEAKSII
TGAKLRLESAWEIAFIRQKSDNIQPENLSCTSLIEASGEYGPQASTLSLFSSPPEILIPKTSSTPKTNNDILSSCEIKTGYNKTVQIPIT
SENSTVGLSNTDVASAWTENYGLQEKISLNPSVRFKAEKLEMALNYLGIQPTKEQHQALRQQVQADSKGTVSFGDFVQVARNLFCLQLDE
VNVGAHEISNILDSQLLPCDSSEADEMERLKCERDDALKEVNTLKEAKAVVEETRALRSRIHLAEAAQRQAHGMEMDYEEVIRLLEAKIT
ELKAQLADYSDQNKESVQDLKKRIMVLDCQLRKSEMARKTFEASTEKLLHFVEAIQEVFSDNSTPLSNLSERRAVLASQTSLTPLGRNGR
SIPATLALESKELVKSVRALLDMDLGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAP
KEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITICSVIGAFSVSCVKGLGIAIKELFAGKPVLRHPLAWIL
LLSLIVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLLHAFKDVSFSLASLPV

--------------------------------------------------------------

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Fusion Gene PPI Analysis for STXBP4-NIPA2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for STXBP4-NIPA2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for STXBP4-NIPA2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneSTXBP4C0006142Malignant neoplasm of breast1CTD_human
HgeneSTXBP4C0678222Breast Carcinoma1CTD_human
HgeneSTXBP4C1257931Mammary Neoplasms, Human1CTD_human
HgeneSTXBP4C1458155Mammary Neoplasms1CTD_human
HgeneSTXBP4C4704874Mammary Carcinoma, Human1CTD_human