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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TBC1D22A-FBLN1 (FusionGDB2 ID:88676)

Fusion Gene Summary for TBC1D22A-FBLN1

check button Fusion gene summary
Fusion gene informationFusion gene name: TBC1D22A-FBLN1
Fusion gene ID: 88676
HgeneTgene
Gene symbol

TBC1D22A

FBLN1

Gene ID

25771

2192

Gene nameTBC1 domain family member 22Afibulin 1
SynonymsC22orf4|HSC79E021FBLN|FIBL1
Cytomap

22q13.31

22q13.31

Type of geneprotein-codingprotein-coding
DescriptionTBC1 domain family member 22Aputative GTPase activatorfibulin-1
Modification date2020031320200313
UniProtAcc.

P23142

Ensembl transtripts involved in fusion geneENST00000337137, ENST00000380995, 
ENST00000407381, ENST00000355704, 
ENST00000472791, ENST00000406733, 
ENST00000348697, ENST00000402984, 
ENST00000262722, ENST00000327858, 
ENST00000442170, ENST00000340923, 
ENST00000476366, 
Fusion gene scores* DoF score34 X 18 X 14=856822 X 22 X 9=4356
# samples 3727
** MAII scorelog2(37/8568*10)=-4.53336130423394
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(27/4356*10)=-4.01197264166608
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TBC1D22A [Title/Abstract] AND FBLN1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTBC1D22A(47193517)-FBLN1(45946372), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneFBLN1

GO:0001933

negative regulation of protein phosphorylation

11792823

TgeneFBLN1

GO:0007162

negative regulation of cell adhesion

11792823

TgeneFBLN1

GO:0007229

integrin-mediated signaling pathway

11792823

TgeneFBLN1

GO:0070373

negative regulation of ERK1 and ERK2 cascade

11792823

TgeneFBLN1

GO:0072378

blood coagulation, fibrin clot formation

7642629

TgeneFBLN1

GO:1900025

negative regulation of substrate adhesion-dependent cell spreading

11792823

TgeneFBLN1

GO:2000146

negative regulation of cell motility

11792823

TgeneFBLN1

GO:2000647

negative regulation of stem cell proliferation

11238726


check buttonFusion gene breakpoints across TBC1D22A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across FBLN1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-85-A50M-01ATBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
ChimerDB4LUSCTCGA-85-A50MTBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
ChimerDB4LUSCTCGA-85-A50MTBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
ChimerDB4LUSCTCGA-85-A50M-01ATBC1D22Achr22

47193517

-FBLN1chr22

45946372

+


Top

Fusion Gene ORF analysis for TBC1D22A-FBLN1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000337137ENST00000348697TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
In-frameENST00000337137ENST00000402984TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
In-frameENST00000337137ENST00000262722TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
In-frameENST00000337137ENST00000327858TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
In-frameENST00000337137ENST00000442170TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
In-frameENST00000337137ENST00000340923TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
5CDS-3UTRENST00000337137ENST00000476366TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
In-frameENST00000380995ENST00000348697TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
In-frameENST00000380995ENST00000402984TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
In-frameENST00000380995ENST00000262722TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
In-frameENST00000380995ENST00000327858TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
In-frameENST00000380995ENST00000442170TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
In-frameENST00000380995ENST00000340923TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
5CDS-3UTRENST00000380995ENST00000476366TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
intron-3CDSENST00000407381ENST00000348697TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
intron-3CDSENST00000407381ENST00000402984TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
intron-3CDSENST00000407381ENST00000262722TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
intron-3CDSENST00000407381ENST00000327858TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
intron-3CDSENST00000407381ENST00000442170TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
intron-3CDSENST00000407381ENST00000340923TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
intron-3UTRENST00000407381ENST00000476366TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
intron-3CDSENST00000355704ENST00000348697TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
intron-3CDSENST00000355704ENST00000402984TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
intron-3CDSENST00000355704ENST00000262722TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
intron-3CDSENST00000355704ENST00000327858TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
intron-3CDSENST00000355704ENST00000442170TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
intron-3CDSENST00000355704ENST00000340923TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
intron-3UTRENST00000355704ENST00000476366TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
intron-3CDSENST00000472791ENST00000348697TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
intron-3CDSENST00000472791ENST00000402984TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
intron-3CDSENST00000472791ENST00000262722TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
intron-3CDSENST00000472791ENST00000327858TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
intron-3CDSENST00000472791ENST00000442170TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
intron-3CDSENST00000472791ENST00000340923TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
intron-3UTRENST00000472791ENST00000476366TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
In-frameENST00000406733ENST00000348697TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
In-frameENST00000406733ENST00000402984TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
In-frameENST00000406733ENST00000262722TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
In-frameENST00000406733ENST00000327858TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
In-frameENST00000406733ENST00000442170TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
In-frameENST00000406733ENST00000340923TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
5CDS-3UTRENST00000406733ENST00000476366TBC1D22Achr22

47193517

+FBLN1chr22

45946372

+
In-frameENST00000337137ENST00000348697TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
In-frameENST00000337137ENST00000402984TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
In-frameENST00000337137ENST00000262722TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
In-frameENST00000337137ENST00000327858TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
In-frameENST00000337137ENST00000442170TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
In-frameENST00000337137ENST00000340923TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
5CDS-3UTRENST00000337137ENST00000476366TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
In-frameENST00000380995ENST00000348697TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
In-frameENST00000380995ENST00000402984TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
In-frameENST00000380995ENST00000262722TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
In-frameENST00000380995ENST00000327858TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
In-frameENST00000380995ENST00000442170TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
In-frameENST00000380995ENST00000340923TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
5CDS-3UTRENST00000380995ENST00000476366TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
intron-3CDSENST00000407381ENST00000348697TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
intron-3CDSENST00000407381ENST00000402984TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
intron-3CDSENST00000407381ENST00000262722TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
intron-3CDSENST00000407381ENST00000327858TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
intron-3CDSENST00000407381ENST00000442170TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
intron-3CDSENST00000407381ENST00000340923TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
intron-3UTRENST00000407381ENST00000476366TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
intron-3CDSENST00000355704ENST00000348697TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
intron-3CDSENST00000355704ENST00000402984TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
intron-3CDSENST00000355704ENST00000262722TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
intron-3CDSENST00000355704ENST00000327858TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
intron-3CDSENST00000355704ENST00000442170TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
intron-3CDSENST00000355704ENST00000340923TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
intron-3UTRENST00000355704ENST00000476366TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
intron-3CDSENST00000472791ENST00000348697TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
intron-3CDSENST00000472791ENST00000402984TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
intron-3CDSENST00000472791ENST00000262722TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
intron-3CDSENST00000472791ENST00000327858TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
intron-3CDSENST00000472791ENST00000442170TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
intron-3CDSENST00000472791ENST00000340923TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
intron-3UTRENST00000472791ENST00000476366TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
In-frameENST00000406733ENST00000348697TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
In-frameENST00000406733ENST00000402984TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
In-frameENST00000406733ENST00000262722TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
In-frameENST00000406733ENST00000327858TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
In-frameENST00000406733ENST00000442170TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
In-frameENST00000406733ENST00000340923TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+
5CDS-3UTRENST00000406733ENST00000476366TBC1D22Achr22

47193517

+FBLN1chr22

45946371

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000337137TBC1D22Achr2247193517+ENST00000348697FBLN1chr2245946372+20308031661341391
ENST00000337137TBC1D22Achr2247193517+ENST00000402984FBLN1chr2245946372+13688031661281371
ENST00000337137TBC1D22Achr2247193517+ENST00000262722FBLN1chr2245946372+13788031661281371
ENST00000337137TBC1D22Achr2247193517+ENST00000327858FBLN1chr2245946372+20318031661341391
ENST00000337137TBC1D22Achr2247193517+ENST00000442170FBLN1chr2245946372+17458031661035289
ENST00000337137TBC1D22Achr2247193517+ENST00000340923FBLN1chr2245946372+1568803166930254
ENST00000380995TBC1D22Achr2247193517+ENST00000348697FBLN1chr2245946372+20197921551330391
ENST00000380995TBC1D22Achr2247193517+ENST00000402984FBLN1chr2245946372+13577921551270371
ENST00000380995TBC1D22Achr2247193517+ENST00000262722FBLN1chr2245946372+13677921551270371
ENST00000380995TBC1D22Achr2247193517+ENST00000327858FBLN1chr2245946372+20207921551330391
ENST00000380995TBC1D22Achr2247193517+ENST00000442170FBLN1chr2245946372+17347921551024289
ENST00000380995TBC1D22Achr2247193517+ENST00000340923FBLN1chr2245946372+1557792155919254
ENST00000406733TBC1D22Achr2247193517+ENST00000348697FBLN1chr2245946372+21118842411422393
ENST00000406733TBC1D22Achr2247193517+ENST00000402984FBLN1chr2245946372+14498842411362373
ENST00000406733TBC1D22Achr2247193517+ENST00000262722FBLN1chr2245946372+14598842411362373
ENST00000406733TBC1D22Achr2247193517+ENST00000327858FBLN1chr2245946372+21128842411422393
ENST00000406733TBC1D22Achr2247193517+ENST00000442170FBLN1chr2245946372+18268842411116291
ENST00000406733TBC1D22Achr2247193517+ENST00000340923FBLN1chr2245946372+16498842411011256
ENST00000337137TBC1D22Achr2247193517+ENST00000348697FBLN1chr2245946371+20308031661341391
ENST00000337137TBC1D22Achr2247193517+ENST00000402984FBLN1chr2245946371+13688031661281371
ENST00000337137TBC1D22Achr2247193517+ENST00000262722FBLN1chr2245946371+13788031661281371
ENST00000337137TBC1D22Achr2247193517+ENST00000327858FBLN1chr2245946371+20318031661341391
ENST00000337137TBC1D22Achr2247193517+ENST00000442170FBLN1chr2245946371+17458031661035289
ENST00000337137TBC1D22Achr2247193517+ENST00000340923FBLN1chr2245946371+1568803166930254
ENST00000380995TBC1D22Achr2247193517+ENST00000348697FBLN1chr2245946371+20197921551330391
ENST00000380995TBC1D22Achr2247193517+ENST00000402984FBLN1chr2245946371+13577921551270371
ENST00000380995TBC1D22Achr2247193517+ENST00000262722FBLN1chr2245946371+13677921551270371
ENST00000380995TBC1D22Achr2247193517+ENST00000327858FBLN1chr2245946371+20207921551330391
ENST00000380995TBC1D22Achr2247193517+ENST00000442170FBLN1chr2245946371+17347921551024289
ENST00000380995TBC1D22Achr2247193517+ENST00000340923FBLN1chr2245946371+1557792155919254
ENST00000406733TBC1D22Achr2247193517+ENST00000348697FBLN1chr2245946371+21118842411422393
ENST00000406733TBC1D22Achr2247193517+ENST00000402984FBLN1chr2245946371+14498842411362373
ENST00000406733TBC1D22Achr2247193517+ENST00000262722FBLN1chr2245946371+14598842411362373
ENST00000406733TBC1D22Achr2247193517+ENST00000327858FBLN1chr2245946371+21128842411422393
ENST00000406733TBC1D22Achr2247193517+ENST00000442170FBLN1chr2245946371+18268842411116291
ENST00000406733TBC1D22Achr2247193517+ENST00000340923FBLN1chr2245946371+16498842411011256

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000337137ENST00000348697TBC1D22Achr2247193517+FBLN1chr2245946372+0.0058897170.9941103
ENST00000337137ENST00000402984TBC1D22Achr2247193517+FBLN1chr2245946372+0.0472592230.9527408
ENST00000337137ENST00000262722TBC1D22Achr2247193517+FBLN1chr2245946372+0.0486580470.9513419
ENST00000337137ENST00000327858TBC1D22Achr2247193517+FBLN1chr2245946372+0.0063169920.993683
ENST00000337137ENST00000442170TBC1D22Achr2247193517+FBLN1chr2245946372+0.0054315050.99456847
ENST00000337137ENST00000340923TBC1D22Achr2247193517+FBLN1chr2245946372+0.0048937390.9951062
ENST00000380995ENST00000348697TBC1D22Achr2247193517+FBLN1chr2245946372+0.0061782340.99382174
ENST00000380995ENST00000402984TBC1D22Achr2247193517+FBLN1chr2245946372+0.0501223880.9498777
ENST00000380995ENST00000262722TBC1D22Achr2247193517+FBLN1chr2245946372+0.0515212230.94847876
ENST00000380995ENST00000327858TBC1D22Achr2247193517+FBLN1chr2245946372+0.0067003230.9932996
ENST00000380995ENST00000442170TBC1D22Achr2247193517+FBLN1chr2245946372+0.0057752530.9942247
ENST00000380995ENST00000340923TBC1D22Achr2247193517+FBLN1chr2245946372+0.0054323560.99456763
ENST00000406733ENST00000348697TBC1D22Achr2247193517+FBLN1chr2245946372+0.0064269060.993573
ENST00000406733ENST00000402984TBC1D22Achr2247193517+FBLN1chr2245946372+0.06737070.9326293
ENST00000406733ENST00000262722TBC1D22Achr2247193517+FBLN1chr2245946372+0.068125050.931875
ENST00000406733ENST00000327858TBC1D22Achr2247193517+FBLN1chr2245946372+0.0070029430.9929971
ENST00000406733ENST00000442170TBC1D22Achr2247193517+FBLN1chr2245946372+0.0105032650.9894967
ENST00000406733ENST00000340923TBC1D22Achr2247193517+FBLN1chr2245946372+0.0073282920.9926717
ENST00000337137ENST00000348697TBC1D22Achr2247193517+FBLN1chr2245946371+0.0058897170.9941103
ENST00000337137ENST00000402984TBC1D22Achr2247193517+FBLN1chr2245946371+0.0472592230.9527408
ENST00000337137ENST00000262722TBC1D22Achr2247193517+FBLN1chr2245946371+0.0486580470.9513419
ENST00000337137ENST00000327858TBC1D22Achr2247193517+FBLN1chr2245946371+0.0063169920.993683
ENST00000337137ENST00000442170TBC1D22Achr2247193517+FBLN1chr2245946371+0.0054315050.99456847
ENST00000337137ENST00000340923TBC1D22Achr2247193517+FBLN1chr2245946371+0.0048937390.9951062
ENST00000380995ENST00000348697TBC1D22Achr2247193517+FBLN1chr2245946371+0.0061782340.99382174
ENST00000380995ENST00000402984TBC1D22Achr2247193517+FBLN1chr2245946371+0.0501223880.9498777
ENST00000380995ENST00000262722TBC1D22Achr2247193517+FBLN1chr2245946371+0.0515212230.94847876
ENST00000380995ENST00000327858TBC1D22Achr2247193517+FBLN1chr2245946371+0.0067003230.9932996
ENST00000380995ENST00000442170TBC1D22Achr2247193517+FBLN1chr2245946371+0.0057752530.9942247
ENST00000380995ENST00000340923TBC1D22Achr2247193517+FBLN1chr2245946371+0.0054323560.99456763
ENST00000406733ENST00000348697TBC1D22Achr2247193517+FBLN1chr2245946371+0.0064269060.993573
ENST00000406733ENST00000402984TBC1D22Achr2247193517+FBLN1chr2245946371+0.06737070.9326293
ENST00000406733ENST00000262722TBC1D22Achr2247193517+FBLN1chr2245946371+0.068125050.931875
ENST00000406733ENST00000327858TBC1D22Achr2247193517+FBLN1chr2245946371+0.0070029430.9929971
ENST00000406733ENST00000442170TBC1D22Achr2247193517+FBLN1chr2245946371+0.0105032650.9894967
ENST00000406733ENST00000340923TBC1D22Achr2247193517+FBLN1chr2245946371+0.0073282920.9926717

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Fusion Genomic Features for TBC1D22A-FBLN1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
TBC1D22Achr2247193517+FBLN1chr2245946371+4.55E-050.99995446
TBC1D22Achr2247193517+FBLN1chr2245946371+4.55E-050.99995446
TBC1D22Achr2247193517+FBLN1chr2245946371+4.55E-050.99995446
TBC1D22Achr2247193517+FBLN1chr2245946371+4.55E-050.99995446

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TBC1D22A-FBLN1


check button Go to

FGviewer for the breakpoints of chr22:47193517-chr22:45946372

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.FBLN1

P23142

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. Has been implicated in a role in cellular transformation and tumor invasion, it appears to be a tumor suppressor. May play a role in haemostasis and thrombosis owing to its ability to bind fibrinogen and incorporate into clots. Could play a significant role in modulating the neurotrophic activities of APP, particularly soluble APP. {ECO:0000269|PubMed:11792823, ECO:0000269|PubMed:9393974, ECO:0000269|PubMed:9466671}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneFBLN1chr22:47193517chr22:45946371ENST000002627221215525_578524.3333333333334684.0DomainEGF-like 9%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946371ENST000003278581217525_578524.3333333333334704.0DomainEGF-like 9%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946371ENST000003409231215525_578524.3333333333334567.0DomainEGF-like 9%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946372ENST000002627221215525_578524.3333333333334684.0DomainEGF-like 9%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946372ENST000003278581217525_578524.3333333333334704.0DomainEGF-like 9%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946372ENST000003409231215525_578524.3333333333334567.0DomainEGF-like 9%3B calcium-binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTBC1D22Achr22:47193517chr22:45946371ENST00000337137+413222_446212.33333333333334518.0DomainRab-GAP TBC
HgeneTBC1D22Achr22:47193517chr22:45946371ENST00000355704+111222_4460440.0DomainRab-GAP TBC
HgeneTBC1D22Achr22:47193517chr22:45946371ENST00000380995+49222_446165.33333333333334325.0DomainRab-GAP TBC
HgeneTBC1D22Achr22:47193517chr22:45946372ENST00000337137+413222_446212.33333333333334518.0DomainRab-GAP TBC
HgeneTBC1D22Achr22:47193517chr22:45946372ENST00000355704+111222_4460440.0DomainRab-GAP TBC
HgeneTBC1D22Achr22:47193517chr22:45946372ENST00000380995+49222_446165.33333333333334325.0DomainRab-GAP TBC
TgeneFBLN1chr22:47193517chr22:45946371ENST000002627221215112_144524.3333333333334684.0DomainAnaphylatoxin-like 3
TgeneFBLN1chr22:47193517chr22:45946371ENST000002627221215176_215524.3333333333334684.0DomainEGF-like 1
TgeneFBLN1chr22:47193517chr22:45946371ENST000002627221215216_261524.3333333333334684.0DomainEGF-like 2%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946371ENST000002627221215262_307524.3333333333334684.0DomainEGF-like 3%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946371ENST000002627221215308_355524.3333333333334684.0DomainEGF-like 4%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946371ENST000002627221215356_398524.3333333333334684.0DomainEGF-like 5%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946371ENST00000262722121536_76524.3333333333334684.0DomainAnaphylatoxin-like 1
TgeneFBLN1chr22:47193517chr22:45946371ENST000002627221215399_440524.3333333333334684.0DomainEGF-like 6%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946371ENST000002627221215441_480524.3333333333334684.0DomainEGF-like 7%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946371ENST000002627221215481_524524.3333333333334684.0DomainEGF-like 8%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946371ENST00000262722121577_111524.3333333333334684.0DomainAnaphylatoxin-like 2
TgeneFBLN1chr22:47193517chr22:45946371ENST000003278581217112_144524.3333333333334704.0DomainAnaphylatoxin-like 3
TgeneFBLN1chr22:47193517chr22:45946371ENST000003278581217176_215524.3333333333334704.0DomainEGF-like 1
TgeneFBLN1chr22:47193517chr22:45946371ENST000003278581217216_261524.3333333333334704.0DomainEGF-like 2%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946371ENST000003278581217262_307524.3333333333334704.0DomainEGF-like 3%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946371ENST000003278581217308_355524.3333333333334704.0DomainEGF-like 4%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946371ENST000003278581217356_398524.3333333333334704.0DomainEGF-like 5%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946371ENST00000327858121736_76524.3333333333334704.0DomainAnaphylatoxin-like 1
TgeneFBLN1chr22:47193517chr22:45946371ENST000003278581217399_440524.3333333333334704.0DomainEGF-like 6%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946371ENST000003278581217441_480524.3333333333334704.0DomainEGF-like 7%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946371ENST000003278581217481_524524.3333333333334704.0DomainEGF-like 8%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946371ENST00000327858121777_111524.3333333333334704.0DomainAnaphylatoxin-like 2
TgeneFBLN1chr22:47193517chr22:45946371ENST000003409231215112_144524.3333333333334567.0DomainAnaphylatoxin-like 3
TgeneFBLN1chr22:47193517chr22:45946371ENST000003409231215176_215524.3333333333334567.0DomainEGF-like 1
TgeneFBLN1chr22:47193517chr22:45946371ENST000003409231215216_261524.3333333333334567.0DomainEGF-like 2%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946371ENST000003409231215262_307524.3333333333334567.0DomainEGF-like 3%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946371ENST000003409231215308_355524.3333333333334567.0DomainEGF-like 4%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946371ENST000003409231215356_398524.3333333333334567.0DomainEGF-like 5%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946371ENST00000340923121536_76524.3333333333334567.0DomainAnaphylatoxin-like 1
TgeneFBLN1chr22:47193517chr22:45946371ENST000003409231215399_440524.3333333333334567.0DomainEGF-like 6%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946371ENST000003409231215441_480524.3333333333334567.0DomainEGF-like 7%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946371ENST000003409231215481_524524.3333333333334567.0DomainEGF-like 8%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946371ENST00000340923121577_111524.3333333333334567.0DomainAnaphylatoxin-like 2
TgeneFBLN1chr22:47193517chr22:45946372ENST000002627221215112_144524.3333333333334684.0DomainAnaphylatoxin-like 3
TgeneFBLN1chr22:47193517chr22:45946372ENST000002627221215176_215524.3333333333334684.0DomainEGF-like 1
TgeneFBLN1chr22:47193517chr22:45946372ENST000002627221215216_261524.3333333333334684.0DomainEGF-like 2%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946372ENST000002627221215262_307524.3333333333334684.0DomainEGF-like 3%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946372ENST000002627221215308_355524.3333333333334684.0DomainEGF-like 4%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946372ENST000002627221215356_398524.3333333333334684.0DomainEGF-like 5%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946372ENST00000262722121536_76524.3333333333334684.0DomainAnaphylatoxin-like 1
TgeneFBLN1chr22:47193517chr22:45946372ENST000002627221215399_440524.3333333333334684.0DomainEGF-like 6%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946372ENST000002627221215441_480524.3333333333334684.0DomainEGF-like 7%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946372ENST000002627221215481_524524.3333333333334684.0DomainEGF-like 8%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946372ENST00000262722121577_111524.3333333333334684.0DomainAnaphylatoxin-like 2
TgeneFBLN1chr22:47193517chr22:45946372ENST000003278581217112_144524.3333333333334704.0DomainAnaphylatoxin-like 3
TgeneFBLN1chr22:47193517chr22:45946372ENST000003278581217176_215524.3333333333334704.0DomainEGF-like 1
TgeneFBLN1chr22:47193517chr22:45946372ENST000003278581217216_261524.3333333333334704.0DomainEGF-like 2%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946372ENST000003278581217262_307524.3333333333334704.0DomainEGF-like 3%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946372ENST000003278581217308_355524.3333333333334704.0DomainEGF-like 4%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946372ENST000003278581217356_398524.3333333333334704.0DomainEGF-like 5%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946372ENST00000327858121736_76524.3333333333334704.0DomainAnaphylatoxin-like 1
TgeneFBLN1chr22:47193517chr22:45946372ENST000003278581217399_440524.3333333333334704.0DomainEGF-like 6%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946372ENST000003278581217441_480524.3333333333334704.0DomainEGF-like 7%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946372ENST000003278581217481_524524.3333333333334704.0DomainEGF-like 8%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946372ENST00000327858121777_111524.3333333333334704.0DomainAnaphylatoxin-like 2
TgeneFBLN1chr22:47193517chr22:45946372ENST000003409231215112_144524.3333333333334567.0DomainAnaphylatoxin-like 3
TgeneFBLN1chr22:47193517chr22:45946372ENST000003409231215176_215524.3333333333334567.0DomainEGF-like 1
TgeneFBLN1chr22:47193517chr22:45946372ENST000003409231215216_261524.3333333333334567.0DomainEGF-like 2%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946372ENST000003409231215262_307524.3333333333334567.0DomainEGF-like 3%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946372ENST000003409231215308_355524.3333333333334567.0DomainEGF-like 4%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946372ENST000003409231215356_398524.3333333333334567.0DomainEGF-like 5%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946372ENST00000340923121536_76524.3333333333334567.0DomainAnaphylatoxin-like 1
TgeneFBLN1chr22:47193517chr22:45946372ENST000003409231215399_440524.3333333333334567.0DomainEGF-like 6%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946372ENST000003409231215441_480524.3333333333334567.0DomainEGF-like 7%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946372ENST000003409231215481_524524.3333333333334567.0DomainEGF-like 8%3B calcium-binding
TgeneFBLN1chr22:47193517chr22:45946372ENST00000340923121577_111524.3333333333334567.0DomainAnaphylatoxin-like 2
TgeneFBLN1chr22:47193517chr22:45946371ENST000002627221215356_440524.3333333333334684.0RegionNote=Self-association and FN1-binding%3B calcium is necessary for homotypic binding%2C but not for heterotypic binding
TgeneFBLN1chr22:47193517chr22:45946371ENST000003278581217356_440524.3333333333334704.0RegionNote=Self-association and FN1-binding%3B calcium is necessary for homotypic binding%2C but not for heterotypic binding
TgeneFBLN1chr22:47193517chr22:45946371ENST000003409231215356_440524.3333333333334567.0RegionNote=Self-association and FN1-binding%3B calcium is necessary for homotypic binding%2C but not for heterotypic binding
TgeneFBLN1chr22:47193517chr22:45946372ENST000002627221215356_440524.3333333333334684.0RegionNote=Self-association and FN1-binding%3B calcium is necessary for homotypic binding%2C but not for heterotypic binding
TgeneFBLN1chr22:47193517chr22:45946372ENST000003278581217356_440524.3333333333334704.0RegionNote=Self-association and FN1-binding%3B calcium is necessary for homotypic binding%2C but not for heterotypic binding
TgeneFBLN1chr22:47193517chr22:45946372ENST000003409231215356_440524.3333333333334567.0RegionNote=Self-association and FN1-binding%3B calcium is necessary for homotypic binding%2C but not for heterotypic binding


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Fusion Gene Sequence for TBC1D22A-FBLN1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000337137_ENST00000348697_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(transcript)=2030nt_BP=803nt
GCGCGTAGGCACAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCA
CAGGAAAGGGCCGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGG
GGCCAGGAAGCAATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCC
ACTGTTACATGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGA
GAGCAATACCAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCAT
GGAGACGGCCAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAG
GCCCGAGGCAGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAG
TGCCAGCGATGCCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCT
CAGCAGCTCAGCGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGA
TGAGTGTGTGACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCC
TGAGAACTACCGCCGCTCCGCAGCCACGCAGAAATCCAAGAAGGGAAGGCAGAACACCCCAGCGGGATCAAGTAAAGAGGACTGCAGGGT
TCTTCCATGGAAGCAGGGGTTGGAGGATACCCACCTTGATGCCTATCTCCCATGTTGCAGGAGATTCACCCGCCCTGAAGAGATCATCTT
CCTCCGGGCCATCACGCCACCGCATCCTGCCAGCCAGGCTAACATCATCTTCGACATCACGGAAGGGAACCTGCGGGACTCTTTTGACAT
CATCAAGCGTTACATGGACGGCATGACCGTGGGTGTCGTGCGCCAGGTGCGGCCCATCGTGGGCCCATTTCATGCCGTCCTGAAGCTGGA
GATGAACTATGTGGTCGGGGGCGTGGTCTCCCACCGAAATGTTGTCAACGTCCACATCTTCGTCTCTGAGTACTGGTTCTGAGGGCTGGT
CTGCCGCACAGCCGCAGGTGCACCTCCAGGCCAAATCATTGCTGCCAGTGACTGTGGTCTGTACTTGTTTATACCCTCAGACTTTTTTAA
TGTTAGGTATTTGTAGCATTAGGCCAACATGTATTAAGCTGAGCCAGATGAATAAGTCCATCTGATGTATTTTCGGTGTTTAAAAAATGA
GCCCAGTTGCTCAACTGTTTGGTTGAAAACCTTGCTCATTTTTTAATGCGAAGGCTAAGTGTCACCCCCTTTCTCTGCCTCTGGCTGGGC
CTTGCTAAGGGCCAAGGAAAGAAAGACATTTTTTAGGGGGCAGCCAGTCCAAATGCCAAAAGAAGACCAGTTCTTGCCCTGATTGTATGA
AATTTGACATTTTGGCACTTTTTTTTTTTTTTTGGCCAATCAGATTTTCTATGTTCTAAGGACATGGCTGCTGTAGAATAGCACAGACGT
GGATGATAAATTATCCCCAGAAGCAGCATGACAGAATGCCTCGGGGAGCACTTGGAAGGGAAATTGCAGTTCTGTTGAAATAGAGGAAAA
TCCCTTGGTAAAGACACAGCCTGTTAGGCTCGTGTGGGCCTCCAGTATGTTCACCAGGGGAATGGCTGGGATTTCTCGGCACTCTGCATC

>In-frame_ENST00000337137_ENST00000348697_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(amino acids)=391AA_start in transcript=166_stop in transcript=1341
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS
DPSTLSSSALSEREASRLDKFKQLLAGPNTDLDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATQKSKKGRQNTPAGSSK
EDCRVLPWKQGLEDTHLDAYLPCCRRFTRPEEIIFLRAITPPHPASQANIIFDITEGNLRDSFDIIKRYMDGMTVGVVRQVRPIVGPFHA

--------------------------------------------------------------
>In-frame_ENST00000337137_ENST00000402984_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(transcript)=1368nt_BP=803nt
GCGCGTAGGCACAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCA
CAGGAAAGGGCCGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGG
GGCCAGGAAGCAATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCC
ACTGTTACATGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGA
GAGCAATACCAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCAT
GGAGACGGCCAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAG
GCCCGAGGCAGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAG
TGCCAGCGATGCCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCT
CAGCAGCTCAGCGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGA
TGAGTGTGTGACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCC
TGAGAACTACCGCCGCTCCGCAGCCACCCGCTGTGAGCGCTTGCCTTGCCATGAGAATCGGGAGTGCTCCAAGCTGCCTCTGAGAATAAC
CTACTACCACCTCTCTTTCCCCACCAACATCCAAGCGCCCGCGGTGGTTTTCCGCATGGGCCCCTCCAGTGCTGTCCCCGGGGACAGCAT
GCAGCTGGCCATCACCGGCGGCAATGAGGAGGGCTTTTTCACCACCCGGAAGGTGAGCCCCCACAGTGGGGTGGTGGCCCTCACCAAGCC
TGTCCCCGAGCCCAGGGACTTGCTCCTGACCGTCAAGATGGATCTCTCTCGCCACGGCACCGTCAGCTCCTTTGTGGCCAAGCTTTTCAT
CTTTGTGTCTGCAGAGCTCTGAGCACTCGCTTCGCGTCGCGGGGTCTCCCTCCTGTTGCTTTCCTAACCCTGCCCTCCGGGGCGTTAATA

>In-frame_ENST00000337137_ENST00000402984_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(amino acids)=371AA_start in transcript=166_stop in transcript=1281
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS
DPSTLSSSALSEREASRLDKFKQLLAGPNTDLDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATRCERLPCHENRECSKL
PLRITYYHLSFPTNIQAPAVVFRMGPSSAVPGDSMQLAITGGNEEGFFTTRKVSPHSGVVALTKPVPEPRDLLLTVKMDLSRHGTVSSFV

--------------------------------------------------------------
>In-frame_ENST00000337137_ENST00000262722_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(transcript)=1378nt_BP=803nt
GCGCGTAGGCACAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCA
CAGGAAAGGGCCGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGG
GGCCAGGAAGCAATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCC
ACTGTTACATGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGA
GAGCAATACCAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCAT
GGAGACGGCCAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAG
GCCCGAGGCAGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAG
TGCCAGCGATGCCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCT
CAGCAGCTCAGCGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGA
TGAGTGTGTGACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCC
TGAGAACTACCGCCGCTCCGCAGCCACCCGCTGTGAGCGCTTGCCTTGCCATGAGAATCGGGAGTGCTCCAAGCTGCCTCTGAGAATAAC
CTACTACCACCTCTCTTTCCCCACCAACATCCAAGCGCCCGCGGTGGTTTTCCGCATGGGCCCCTCCAGTGCTGTCCCCGGGGACAGCAT
GCAGCTGGCCATCACCGGCGGCAATGAGGAGGGCTTTTTCACCACCCGGAAGGTGAGCCCCCACAGTGGGGTGGTGGCCCTCACCAAGCC
TGTCCCCGAGCCCAGGGACTTGCTCCTGACCGTCAAGATGGATCTCTCTCGCCACGGCACCGTCAGCTCCTTTGTGGCCAAGCTTTTCAT
CTTTGTGTCTGCAGAGCTCTGAGCACTCGCTTCGCGTCGCGGGGTCTCCCTCCTGTTGCTTTCCTAACCCTGCCCTCCGGGGCGTTAATA

>In-frame_ENST00000337137_ENST00000262722_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(amino acids)=371AA_start in transcript=166_stop in transcript=1281
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS
DPSTLSSSALSEREASRLDKFKQLLAGPNTDLDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATRCERLPCHENRECSKL
PLRITYYHLSFPTNIQAPAVVFRMGPSSAVPGDSMQLAITGGNEEGFFTTRKVSPHSGVVALTKPVPEPRDLLLTVKMDLSRHGTVSSFV

--------------------------------------------------------------
>In-frame_ENST00000337137_ENST00000327858_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(transcript)=2031nt_BP=803nt
GCGCGTAGGCACAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCA
CAGGAAAGGGCCGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGG
GGCCAGGAAGCAATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCC
ACTGTTACATGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGA
GAGCAATACCAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCAT
GGAGACGGCCAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAG
GCCCGAGGCAGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAG
TGCCAGCGATGCCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCT
CAGCAGCTCAGCGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGA
TGAGTGTGTGACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCC
TGAGAACTACCGCCGCTCCGCAGCCACGCTCCAGCAGGAGAAGACAGACACGGTCCGCTGCATCAAGTCCTGCCGCCCCAACGATGTCAC
ATGCGTGTTCGACCCCGTGCACACCATCTCCCACACCGTCATCTCGCTGCCTACCTTCCGCGAGTTCACCCGCCCTGAAGAGATCATCTT
CCTCCGGGCCATCACGCCACCGCATCCTGCCAGCCAGGCTAACATCATCTTCGACATCACGGAAGGGAACCTGCGGGACTCTTTTGACAT
CATCAAGCGTTACATGGACGGCATGACCGTGGGTGTCGTGCGCCAGGTGCGGCCCATCGTGGGCCCATTTCATGCCGTCCTGAAGCTGGA
GATGAACTATGTGGTCGGGGGCGTGGTCTCCCACCGAAATGTTGTCAACGTCCACATCTTCGTCTCTGAGTACTGGTTCTGAGGGCTGGT
CTGCCGCACAGCCGCAGGTGCACCTCCAGGCCAAATCATTGCTGCCAGTGACTGTGGTCTGTACTTGTTTATACCCTCAGACTTTTTTAA
TGTTAGGTATTTGTAGCATTAGGCCAACATGTATTAAGCTGAGCCAGATGAATAAGTCCATCTGATGTATTTTCGGTGTTTAAAAAATGA
GCCCAGTTGCTCAACTGTTTGGTTGAAAACCTTGCTCATTTTTTAATGCGAAGGCTAAGTGTCACCCCCTTTCTCTGCCTCTGGCTGGGC
CTTGCTAAGGGCCAAGGAAAGAAAGACATTTTTTAGGGGGCAGCCAGTCCAAATGCCAAAAGAAGACCAGTTCTTGCCCTGATTGTATGA
AATTTGACATTTTGGCACTTTTTTTTTTTTTTTGGCCAATCAGATTTTCTATGTTCTAAGGACATGGCTGCTGTAGAATAGCACAGACGT
GGATGATAAATTATCCCCAGAAGCAGCATGACAGAATGCCTCGGGGAGCACTTGGAAGGGAAATTGCAGTTCTGTTGAAATAGAGGAAAA
TCCCTTGGTAAAGACACAGCCTGTTAGGCTCGTGTGGGCCTCCAGTATGTTCACCAGGGGAATGGCTGGGATTTCTCGGCACTCTGCATC

>In-frame_ENST00000337137_ENST00000327858_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(amino acids)=391AA_start in transcript=166_stop in transcript=1341
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS
DPSTLSSSALSEREASRLDKFKQLLAGPNTDLDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIKSCR
PNDVTCVFDPVHTISHTVISLPTFREFTRPEEIIFLRAITPPHPASQANIIFDITEGNLRDSFDIIKRYMDGMTVGVVRQVRPIVGPFHA

--------------------------------------------------------------
>In-frame_ENST00000337137_ENST00000442170_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(transcript)=1745nt_BP=803nt
GCGCGTAGGCACAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCA
CAGGAAAGGGCCGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGG
GGCCAGGAAGCAATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCC
ACTGTTACATGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGA
GAGCAATACCAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCAT
GGAGACGGCCAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAG
GCCCGAGGCAGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAG
TGCCAGCGATGCCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCT
CAGCAGCTCAGCGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGA
TGAGTGTGTGACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCC
TGAGAACTACCGCCGCTCCGCAGCCACGCAGAAATCCAAGAAGGGAAGGCAGAACACCCCAGCGGGATCAAGTAAAGAGGACTGCAGGGT
TCTTCCATGGAAGCAGGGGTTGGAGGATACCCACCTTGATGCCTAGTGAGGAAGATGGACCTGGACAGACAGTCAGCTCCACACCTTGCG
CTGAGCAGCTGTGATTGTGCCACGGGAGCATGAGCCCTTTTCCCCACGGCCCTTGCCACTGTCTCCTGGCCCTCTCTCTGATCATGCCAG
GTTTGCACCAGCCTCGAGTCTCCCATGTTGTAGTACATTCTCCAAGATGCAGCCCAGGAGCCTCTCTGAAGGACCAGTCTGGTTACGATG
GTCTGAGCTTCCTTAGAACCTTCCATGGTTGTCTTTTCCCAGCAGATGAAGCATAGCCTCCTTGGAATGGCATGGGAGGCCTGGCCTGAT
CTGGCCTCTGCCCACCCTTTGAGCTGCACCTGCCCCACCCCAGCTCATCCATGTGCTTGTACCCTGGCCCCACGGGGAGGCTTGCCCTTC
CCTGAATCTGCCTTCTTGTGGCTTTAGCATGTGCCATGCTGTCCCCCTGCAGACTGCCATTCTCCTTGCAGACTTGGCTCAGAAGTCACC
TCCTCAGTGCAGTTAGCCTGAGCTCCCCTGGCCCCAGGTGCCTCCATCAGAGCATTTACCCCATTGTGTTGTGGCTGTTCCTTAACGTCC
CCACTAGCCAGGCTCTTTGAGGGCAGGGATTGTGTCTGGTTAATTTCTGTATTCTCTGCAACTTTGCAATGTTTGGCTTGAAGAAGGAGC

>In-frame_ENST00000337137_ENST00000442170_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(amino acids)=289AA_start in transcript=166_stop in transcript=1035
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS
DPSTLSSSALSEREASRLDKFKQLLAGPNTDLDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATQKSKKGRQNTPAGSSK

--------------------------------------------------------------
>In-frame_ENST00000337137_ENST00000340923_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(transcript)=1568nt_BP=803nt
GCGCGTAGGCACAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCA
CAGGAAAGGGCCGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGG
GGCCAGGAAGCAATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCC
ACTGTTACATGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGA
GAGCAATACCAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCAT
GGAGACGGCCAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAG
GCCCGAGGCAGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAG
TGCCAGCGATGCCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCT
CAGCAGCTCAGCGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGA
TGAGTGTGTGACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCC
TGAGAACTACCGCCGCTCCGCAGCCACATGATCGTAGGGAACTCTGCATGAGGCCATCGGTGCAGGCTGGAGAAGAGAAGGCAAGTTGGC
AGGAGTGGAGACCACGGGCATTTGAGCCACTTCCTCATGTAACTTAACTTGTGCCTTCAGGACCTGCTCAAGCCCGATCACGTATATACC
ACTTCCATTTGATGATGGAATGCTGCTGTTCATGACCAACTTTATGGCTAGATGGGTCAGAAAGCACCCAGTTCATGATAGGCAGTTCAG
GTCATATGGTGACTTGATGACCCAGAGTCAAACATTCAGTTTCCACCAAAGCCCAGTAACAGGCCAAGAGCTGTCTCTCAAAAGGAGAGT
AGTTATCTGCAGAAGATGGCAGGGCCTTGCTCCGAAAGCCTAGAGACCGCCACTGTGATTCACCTATGGGGGCCTGCCAAAGGCTGCAGC
CAGCATCCTTATCTGCCACTGACACCTCAAGCAACATTGGATCTGCTGGGTCATATGGCCCAAGTGGCAGAGCAACTTGCACAACAGCCT
GGACCTGTCATAGAGCTTTCTCCTGTTCTGGACCCCACTCAAAACTGGCAGCCTTTCAGGTCACTCGATAAATGTGCTGGAGTAACACTC

>In-frame_ENST00000337137_ENST00000340923_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(amino acids)=254AA_start in transcript=166_stop in transcript=930
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS

--------------------------------------------------------------
>In-frame_ENST00000380995_ENST00000348697_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(transcript)=2019nt_BP=792nt
CAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCACAGGAAAGGGC
CGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGGGGCCAGGAAGC
AATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACATG
GCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATACCA
GCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGCCA
ACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGCAG
AGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAGTGCCAGCGATG
CCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCTCAGCAGCTCAG
CGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGATGAGTGTGTGA
CTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGAGAACTACC
GCCGCTCCGCAGCCACGCAGAAATCCAAGAAGGGAAGGCAGAACACCCCAGCGGGATCAAGTAAAGAGGACTGCAGGGTTCTTCCATGGA
AGCAGGGGTTGGAGGATACCCACCTTGATGCCTATCTCCCATGTTGCAGGAGATTCACCCGCCCTGAAGAGATCATCTTCCTCCGGGCCA
TCACGCCACCGCATCCTGCCAGCCAGGCTAACATCATCTTCGACATCACGGAAGGGAACCTGCGGGACTCTTTTGACATCATCAAGCGTT
ACATGGACGGCATGACCGTGGGTGTCGTGCGCCAGGTGCGGCCCATCGTGGGCCCATTTCATGCCGTCCTGAAGCTGGAGATGAACTATG
TGGTCGGGGGCGTGGTCTCCCACCGAAATGTTGTCAACGTCCACATCTTCGTCTCTGAGTACTGGTTCTGAGGGCTGGTCTGCCGCACAG
CCGCAGGTGCACCTCCAGGCCAAATCATTGCTGCCAGTGACTGTGGTCTGTACTTGTTTATACCCTCAGACTTTTTTAATGTTAGGTATT
TGTAGCATTAGGCCAACATGTATTAAGCTGAGCCAGATGAATAAGTCCATCTGATGTATTTTCGGTGTTTAAAAAATGAGCCCAGTTGCT
CAACTGTTTGGTTGAAAACCTTGCTCATTTTTTAATGCGAAGGCTAAGTGTCACCCCCTTTCTCTGCCTCTGGCTGGGCCTTGCTAAGGG
CCAAGGAAAGAAAGACATTTTTTAGGGGGCAGCCAGTCCAAATGCCAAAAGAAGACCAGTTCTTGCCCTGATTGTATGAAATTTGACATT
TTGGCACTTTTTTTTTTTTTTTGGCCAATCAGATTTTCTATGTTCTAAGGACATGGCTGCTGTAGAATAGCACAGACGTGGATGATAAAT
TATCCCCAGAAGCAGCATGACAGAATGCCTCGGGGAGCACTTGGAAGGGAAATTGCAGTTCTGTTGAAATAGAGGAAAATCCCTTGGTAA
AGACACAGCCTGTTAGGCTCGTGTGGGCCTCCAGTATGTTCACCAGGGGAATGGCTGGGATTTCTCGGCACTCTGCATCATCCATCTTTT

>In-frame_ENST00000380995_ENST00000348697_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(amino acids)=391AA_start in transcript=155_stop in transcript=1330
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS
DPSTLSSSALSEREASRLDKFKQLLAGPNTDLDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATQKSKKGRQNTPAGSSK
EDCRVLPWKQGLEDTHLDAYLPCCRRFTRPEEIIFLRAITPPHPASQANIIFDITEGNLRDSFDIIKRYMDGMTVGVVRQVRPIVGPFHA

--------------------------------------------------------------
>In-frame_ENST00000380995_ENST00000402984_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(transcript)=1357nt_BP=792nt
CAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCACAGGAAAGGGC
CGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGGGGCCAGGAAGC
AATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACATG
GCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATACCA
GCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGCCA
ACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGCAG
AGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAGTGCCAGCGATG
CCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCTCAGCAGCTCAG
CGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGATGAGTGTGTGA
CTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGAGAACTACC
GCCGCTCCGCAGCCACCCGCTGTGAGCGCTTGCCTTGCCATGAGAATCGGGAGTGCTCCAAGCTGCCTCTGAGAATAACCTACTACCACC
TCTCTTTCCCCACCAACATCCAAGCGCCCGCGGTGGTTTTCCGCATGGGCCCCTCCAGTGCTGTCCCCGGGGACAGCATGCAGCTGGCCA
TCACCGGCGGCAATGAGGAGGGCTTTTTCACCACCCGGAAGGTGAGCCCCCACAGTGGGGTGGTGGCCCTCACCAAGCCTGTCCCCGAGC
CCAGGGACTTGCTCCTGACCGTCAAGATGGATCTCTCTCGCCACGGCACCGTCAGCTCCTTTGTGGCCAAGCTTTTCATCTTTGTGTCTG
CAGAGCTCTGAGCACTCGCTTCGCGTCGCGGGGTCTCCCTCCTGTTGCTTTCCTAACCCTGCCCTCCGGGGCGTTAATAAAGTCTTAGCA

>In-frame_ENST00000380995_ENST00000402984_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(amino acids)=371AA_start in transcript=155_stop in transcript=1270
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS
DPSTLSSSALSEREASRLDKFKQLLAGPNTDLDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATRCERLPCHENRECSKL
PLRITYYHLSFPTNIQAPAVVFRMGPSSAVPGDSMQLAITGGNEEGFFTTRKVSPHSGVVALTKPVPEPRDLLLTVKMDLSRHGTVSSFV

--------------------------------------------------------------
>In-frame_ENST00000380995_ENST00000262722_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(transcript)=1367nt_BP=792nt
CAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCACAGGAAAGGGC
CGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGGGGCCAGGAAGC
AATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACATG
GCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATACCA
GCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGCCA
ACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGCAG
AGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAGTGCCAGCGATG
CCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCTCAGCAGCTCAG
CGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGATGAGTGTGTGA
CTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGAGAACTACC
GCCGCTCCGCAGCCACCCGCTGTGAGCGCTTGCCTTGCCATGAGAATCGGGAGTGCTCCAAGCTGCCTCTGAGAATAACCTACTACCACC
TCTCTTTCCCCACCAACATCCAAGCGCCCGCGGTGGTTTTCCGCATGGGCCCCTCCAGTGCTGTCCCCGGGGACAGCATGCAGCTGGCCA
TCACCGGCGGCAATGAGGAGGGCTTTTTCACCACCCGGAAGGTGAGCCCCCACAGTGGGGTGGTGGCCCTCACCAAGCCTGTCCCCGAGC
CCAGGGACTTGCTCCTGACCGTCAAGATGGATCTCTCTCGCCACGGCACCGTCAGCTCCTTTGTGGCCAAGCTTTTCATCTTTGTGTCTG
CAGAGCTCTGAGCACTCGCTTCGCGTCGCGGGGTCTCCCTCCTGTTGCTTTCCTAACCCTGCCCTCCGGGGCGTTAATAAAGTCTTAGCA

>In-frame_ENST00000380995_ENST00000262722_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(amino acids)=371AA_start in transcript=155_stop in transcript=1270
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS
DPSTLSSSALSEREASRLDKFKQLLAGPNTDLDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATRCERLPCHENRECSKL
PLRITYYHLSFPTNIQAPAVVFRMGPSSAVPGDSMQLAITGGNEEGFFTTRKVSPHSGVVALTKPVPEPRDLLLTVKMDLSRHGTVSSFV

--------------------------------------------------------------
>In-frame_ENST00000380995_ENST00000327858_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(transcript)=2020nt_BP=792nt
CAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCACAGGAAAGGGC
CGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGGGGCCAGGAAGC
AATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACATG
GCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATACCA
GCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGCCA
ACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGCAG
AGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAGTGCCAGCGATG
CCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCTCAGCAGCTCAG
CGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGATGAGTGTGTGA
CTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGAGAACTACC
GCCGCTCCGCAGCCACGCTCCAGCAGGAGAAGACAGACACGGTCCGCTGCATCAAGTCCTGCCGCCCCAACGATGTCACATGCGTGTTCG
ACCCCGTGCACACCATCTCCCACACCGTCATCTCGCTGCCTACCTTCCGCGAGTTCACCCGCCCTGAAGAGATCATCTTCCTCCGGGCCA
TCACGCCACCGCATCCTGCCAGCCAGGCTAACATCATCTTCGACATCACGGAAGGGAACCTGCGGGACTCTTTTGACATCATCAAGCGTT
ACATGGACGGCATGACCGTGGGTGTCGTGCGCCAGGTGCGGCCCATCGTGGGCCCATTTCATGCCGTCCTGAAGCTGGAGATGAACTATG
TGGTCGGGGGCGTGGTCTCCCACCGAAATGTTGTCAACGTCCACATCTTCGTCTCTGAGTACTGGTTCTGAGGGCTGGTCTGCCGCACAG
CCGCAGGTGCACCTCCAGGCCAAATCATTGCTGCCAGTGACTGTGGTCTGTACTTGTTTATACCCTCAGACTTTTTTAATGTTAGGTATT
TGTAGCATTAGGCCAACATGTATTAAGCTGAGCCAGATGAATAAGTCCATCTGATGTATTTTCGGTGTTTAAAAAATGAGCCCAGTTGCT
CAACTGTTTGGTTGAAAACCTTGCTCATTTTTTAATGCGAAGGCTAAGTGTCACCCCCTTTCTCTGCCTCTGGCTGGGCCTTGCTAAGGG
CCAAGGAAAGAAAGACATTTTTTAGGGGGCAGCCAGTCCAAATGCCAAAAGAAGACCAGTTCTTGCCCTGATTGTATGAAATTTGACATT
TTGGCACTTTTTTTTTTTTTTTGGCCAATCAGATTTTCTATGTTCTAAGGACATGGCTGCTGTAGAATAGCACAGACGTGGATGATAAAT
TATCCCCAGAAGCAGCATGACAGAATGCCTCGGGGAGCACTTGGAAGGGAAATTGCAGTTCTGTTGAAATAGAGGAAAATCCCTTGGTAA
AGACACAGCCTGTTAGGCTCGTGTGGGCCTCCAGTATGTTCACCAGGGGAATGGCTGGGATTTCTCGGCACTCTGCATCATCCATCTTTT

>In-frame_ENST00000380995_ENST00000327858_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(amino acids)=391AA_start in transcript=155_stop in transcript=1330
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS
DPSTLSSSALSEREASRLDKFKQLLAGPNTDLDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIKSCR
PNDVTCVFDPVHTISHTVISLPTFREFTRPEEIIFLRAITPPHPASQANIIFDITEGNLRDSFDIIKRYMDGMTVGVVRQVRPIVGPFHA

--------------------------------------------------------------
>In-frame_ENST00000380995_ENST00000442170_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(transcript)=1734nt_BP=792nt
CAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCACAGGAAAGGGC
CGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGGGGCCAGGAAGC
AATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACATG
GCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATACCA
GCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGCCA
ACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGCAG
AGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAGTGCCAGCGATG
CCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCTCAGCAGCTCAG
CGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGATGAGTGTGTGA
CTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGAGAACTACC
GCCGCTCCGCAGCCACGCAGAAATCCAAGAAGGGAAGGCAGAACACCCCAGCGGGATCAAGTAAAGAGGACTGCAGGGTTCTTCCATGGA
AGCAGGGGTTGGAGGATACCCACCTTGATGCCTAGTGAGGAAGATGGACCTGGACAGACAGTCAGCTCCACACCTTGCGCTGAGCAGCTG
TGATTGTGCCACGGGAGCATGAGCCCTTTTCCCCACGGCCCTTGCCACTGTCTCCTGGCCCTCTCTCTGATCATGCCAGGTTTGCACCAG
CCTCGAGTCTCCCATGTTGTAGTACATTCTCCAAGATGCAGCCCAGGAGCCTCTCTGAAGGACCAGTCTGGTTACGATGGTCTGAGCTTC
CTTAGAACCTTCCATGGTTGTCTTTTCCCAGCAGATGAAGCATAGCCTCCTTGGAATGGCATGGGAGGCCTGGCCTGATCTGGCCTCTGC
CCACCCTTTGAGCTGCACCTGCCCCACCCCAGCTCATCCATGTGCTTGTACCCTGGCCCCACGGGGAGGCTTGCCCTTCCCTGAATCTGC
CTTCTTGTGGCTTTAGCATGTGCCATGCTGTCCCCCTGCAGACTGCCATTCTCCTTGCAGACTTGGCTCAGAAGTCACCTCCTCAGTGCA
GTTAGCCTGAGCTCCCCTGGCCCCAGGTGCCTCCATCAGAGCATTTACCCCATTGTGTTGTGGCTGTTCCTTAACGTCCCCACTAGCCAG
GCTCTTTGAGGGCAGGGATTGTGTCTGGTTAATTTCTGTATTCTCTGCAACTTTGCAATGTTTGGCTTGAAGAAGGAGCTCAGTAAACAT

>In-frame_ENST00000380995_ENST00000442170_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(amino acids)=289AA_start in transcript=155_stop in transcript=1024
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS
DPSTLSSSALSEREASRLDKFKQLLAGPNTDLDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATQKSKKGRQNTPAGSSK

--------------------------------------------------------------
>In-frame_ENST00000380995_ENST00000340923_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(transcript)=1557nt_BP=792nt
CAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCACAGGAAAGGGC
CGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGGGGCCAGGAAGC
AATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACATG
GCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATACCA
GCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGCCA
ACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGCAG
AGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAGTGCCAGCGATG
CCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCTCAGCAGCTCAG
CGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGATGAGTGTGTGA
CTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGAGAACTACC
GCCGCTCCGCAGCCACATGATCGTAGGGAACTCTGCATGAGGCCATCGGTGCAGGCTGGAGAAGAGAAGGCAAGTTGGCAGGAGTGGAGA
CCACGGGCATTTGAGCCACTTCCTCATGTAACTTAACTTGTGCCTTCAGGACCTGCTCAAGCCCGATCACGTATATACCACTTCCATTTG
ATGATGGAATGCTGCTGTTCATGACCAACTTTATGGCTAGATGGGTCAGAAAGCACCCAGTTCATGATAGGCAGTTCAGGTCATATGGTG
ACTTGATGACCCAGAGTCAAACATTCAGTTTCCACCAAAGCCCAGTAACAGGCCAAGAGCTGTCTCTCAAAAGGAGAGTAGTTATCTGCA
GAAGATGGCAGGGCCTTGCTCCGAAAGCCTAGAGACCGCCACTGTGATTCACCTATGGGGGCCTGCCAAAGGCTGCAGCCAGCATCCTTA
TCTGCCACTGACACCTCAAGCAACATTGGATCTGCTGGGTCATATGGCCCAAGTGGCAGAGCAACTTGCACAACAGCCTGGACCTGTCAT
AGAGCTTTCTCCTGTTCTGGACCCCACTCAAAACTGGCAGCCTTTCAGGTCACTCGATAAATGTGCTGGAGTAACACTCAAACGAGGAAT

>In-frame_ENST00000380995_ENST00000340923_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(amino acids)=254AA_start in transcript=155_stop in transcript=919
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS

--------------------------------------------------------------
>In-frame_ENST00000406733_ENST00000348697_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(transcript)=2111nt_BP=884nt
AGAAGTCTGTGCCCTTACCCATCACAGCCTCATCCTTATCTCCTCCATTCCCTAGGGGACTTAACAGGTGTTGAAATTATTACAGAGAAA
GCTGACTCACTCACCAGGAATCTGATCCTGCTGTGGGCTGGCTTGGGTGGAGGTGTTCCTCCCGCCCCCGCACCCATCCTCCTGTTTGAA
CTCAGGCTGCTGCCTGCTGGGCCTGCCTGCCCTTGGAGCCCTGCTGAGCTCAGCCTGAGGCCTGGCTCCTCCAGGCTGGGGGAAAACCAG
GCTTGCTGTGCTCGGCAGCAGAGATTCTTCTGGAGTGAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACA
TGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATAC
CAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGC
CAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGC
AGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAGTGCCAGCGA
TGCCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCTCAGCAGCTC
AGCGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGATGAGTGTGT
GACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGAGAACTA
CCGCCGCTCCGCAGCCACGCAGAAATCCAAGAAGGGAAGGCAGAACACCCCAGCGGGATCAAGTAAAGAGGACTGCAGGGTTCTTCCATG
GAAGCAGGGGTTGGAGGATACCCACCTTGATGCCTATCTCCCATGTTGCAGGAGATTCACCCGCCCTGAAGAGATCATCTTCCTCCGGGC
CATCACGCCACCGCATCCTGCCAGCCAGGCTAACATCATCTTCGACATCACGGAAGGGAACCTGCGGGACTCTTTTGACATCATCAAGCG
TTACATGGACGGCATGACCGTGGGTGTCGTGCGCCAGGTGCGGCCCATCGTGGGCCCATTTCATGCCGTCCTGAAGCTGGAGATGAACTA
TGTGGTCGGGGGCGTGGTCTCCCACCGAAATGTTGTCAACGTCCACATCTTCGTCTCTGAGTACTGGTTCTGAGGGCTGGTCTGCCGCAC
AGCCGCAGGTGCACCTCCAGGCCAAATCATTGCTGCCAGTGACTGTGGTCTGTACTTGTTTATACCCTCAGACTTTTTTAATGTTAGGTA
TTTGTAGCATTAGGCCAACATGTATTAAGCTGAGCCAGATGAATAAGTCCATCTGATGTATTTTCGGTGTTTAAAAAATGAGCCCAGTTG
CTCAACTGTTTGGTTGAAAACCTTGCTCATTTTTTAATGCGAAGGCTAAGTGTCACCCCCTTTCTCTGCCTCTGGCTGGGCCTTGCTAAG
GGCCAAGGAAAGAAAGACATTTTTTAGGGGGCAGCCAGTCCAAATGCCAAAAGAAGACCAGTTCTTGCCCTGATTGTATGAAATTTGACA
TTTTGGCACTTTTTTTTTTTTTTTGGCCAATCAGATTTTCTATGTTCTAAGGACATGGCTGCTGTAGAATAGCACAGACGTGGATGATAA
ATTATCCCCAGAAGCAGCATGACAGAATGCCTCGGGGAGCACTTGGAAGGGAAATTGCAGTTCTGTTGAAATAGAGGAAAATCCCTTGGT
AAAGACACAGCCTGTTAGGCTCGTGTGGGCCTCCAGTATGTTCACCAGGGGAATGGCTGGGATTTCTCGGCACTCTGCATCATCCATCTT

>In-frame_ENST00000406733_ENST00000348697_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(amino acids)=393AA_start in transcript=241_stop in transcript=1422
MAPPGWGKTRLAVLGSRDSSGVSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAES
LNSEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGG
TSDPSTLSSSALSEREASRLDKFKQLLAGPNTDLDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATQKSKKGRQNTPAGS
SKEDCRVLPWKQGLEDTHLDAYLPCCRRFTRPEEIIFLRAITPPHPASQANIIFDITEGNLRDSFDIIKRYMDGMTVGVVRQVRPIVGPF

--------------------------------------------------------------
>In-frame_ENST00000406733_ENST00000402984_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(transcript)=1449nt_BP=884nt
AGAAGTCTGTGCCCTTACCCATCACAGCCTCATCCTTATCTCCTCCATTCCCTAGGGGACTTAACAGGTGTTGAAATTATTACAGAGAAA
GCTGACTCACTCACCAGGAATCTGATCCTGCTGTGGGCTGGCTTGGGTGGAGGTGTTCCTCCCGCCCCCGCACCCATCCTCCTGTTTGAA
CTCAGGCTGCTGCCTGCTGGGCCTGCCTGCCCTTGGAGCCCTGCTGAGCTCAGCCTGAGGCCTGGCTCCTCCAGGCTGGGGGAAAACCAG
GCTTGCTGTGCTCGGCAGCAGAGATTCTTCTGGAGTGAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACA
TGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATAC
CAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGC
CAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGC
AGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAGTGCCAGCGA
TGCCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCTCAGCAGCTC
AGCGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGATGAGTGTGT
GACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGAGAACTA
CCGCCGCTCCGCAGCCACCCGCTGTGAGCGCTTGCCTTGCCATGAGAATCGGGAGTGCTCCAAGCTGCCTCTGAGAATAACCTACTACCA
CCTCTCTTTCCCCACCAACATCCAAGCGCCCGCGGTGGTTTTCCGCATGGGCCCCTCCAGTGCTGTCCCCGGGGACAGCATGCAGCTGGC
CATCACCGGCGGCAATGAGGAGGGCTTTTTCACCACCCGGAAGGTGAGCCCCCACAGTGGGGTGGTGGCCCTCACCAAGCCTGTCCCCGA
GCCCAGGGACTTGCTCCTGACCGTCAAGATGGATCTCTCTCGCCACGGCACCGTCAGCTCCTTTGTGGCCAAGCTTTTCATCTTTGTGTC
TGCAGAGCTCTGAGCACTCGCTTCGCGTCGCGGGGTCTCCCTCCTGTTGCTTTCCTAACCCTGCCCTCCGGGGCGTTAATAAAGTCTTAG

>In-frame_ENST00000406733_ENST00000402984_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(amino acids)=373AA_start in transcript=241_stop in transcript=1362
MAPPGWGKTRLAVLGSRDSSGVSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAES
LNSEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGG
TSDPSTLSSSALSEREASRLDKFKQLLAGPNTDLDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATRCERLPCHENRECS
KLPLRITYYHLSFPTNIQAPAVVFRMGPSSAVPGDSMQLAITGGNEEGFFTTRKVSPHSGVVALTKPVPEPRDLLLTVKMDLSRHGTVSS

--------------------------------------------------------------
>In-frame_ENST00000406733_ENST00000262722_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(transcript)=1459nt_BP=884nt
AGAAGTCTGTGCCCTTACCCATCACAGCCTCATCCTTATCTCCTCCATTCCCTAGGGGACTTAACAGGTGTTGAAATTATTACAGAGAAA
GCTGACTCACTCACCAGGAATCTGATCCTGCTGTGGGCTGGCTTGGGTGGAGGTGTTCCTCCCGCCCCCGCACCCATCCTCCTGTTTGAA
CTCAGGCTGCTGCCTGCTGGGCCTGCCTGCCCTTGGAGCCCTGCTGAGCTCAGCCTGAGGCCTGGCTCCTCCAGGCTGGGGGAAAACCAG
GCTTGCTGTGCTCGGCAGCAGAGATTCTTCTGGAGTGAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACA
TGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATAC
CAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGC
CAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGC
AGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAGTGCCAGCGA
TGCCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCTCAGCAGCTC
AGCGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGATGAGTGTGT
GACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGAGAACTA
CCGCCGCTCCGCAGCCACCCGCTGTGAGCGCTTGCCTTGCCATGAGAATCGGGAGTGCTCCAAGCTGCCTCTGAGAATAACCTACTACCA
CCTCTCTTTCCCCACCAACATCCAAGCGCCCGCGGTGGTTTTCCGCATGGGCCCCTCCAGTGCTGTCCCCGGGGACAGCATGCAGCTGGC
CATCACCGGCGGCAATGAGGAGGGCTTTTTCACCACCCGGAAGGTGAGCCCCCACAGTGGGGTGGTGGCCCTCACCAAGCCTGTCCCCGA
GCCCAGGGACTTGCTCCTGACCGTCAAGATGGATCTCTCTCGCCACGGCACCGTCAGCTCCTTTGTGGCCAAGCTTTTCATCTTTGTGTC
TGCAGAGCTCTGAGCACTCGCTTCGCGTCGCGGGGTCTCCCTCCTGTTGCTTTCCTAACCCTGCCCTCCGGGGCGTTAATAAAGTCTTAG

>In-frame_ENST00000406733_ENST00000262722_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(amino acids)=373AA_start in transcript=241_stop in transcript=1362
MAPPGWGKTRLAVLGSRDSSGVSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAES
LNSEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGG
TSDPSTLSSSALSEREASRLDKFKQLLAGPNTDLDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATRCERLPCHENRECS
KLPLRITYYHLSFPTNIQAPAVVFRMGPSSAVPGDSMQLAITGGNEEGFFTTRKVSPHSGVVALTKPVPEPRDLLLTVKMDLSRHGTVSS

--------------------------------------------------------------
>In-frame_ENST00000406733_ENST00000327858_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(transcript)=2112nt_BP=884nt
AGAAGTCTGTGCCCTTACCCATCACAGCCTCATCCTTATCTCCTCCATTCCCTAGGGGACTTAACAGGTGTTGAAATTATTACAGAGAAA
GCTGACTCACTCACCAGGAATCTGATCCTGCTGTGGGCTGGCTTGGGTGGAGGTGTTCCTCCCGCCCCCGCACCCATCCTCCTGTTTGAA
CTCAGGCTGCTGCCTGCTGGGCCTGCCTGCCCTTGGAGCCCTGCTGAGCTCAGCCTGAGGCCTGGCTCCTCCAGGCTGGGGGAAAACCAG
GCTTGCTGTGCTCGGCAGCAGAGATTCTTCTGGAGTGAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACA
TGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATAC
CAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGC
CAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGC
AGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAGTGCCAGCGA
TGCCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCTCAGCAGCTC
AGCGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGATGAGTGTGT
GACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGAGAACTA
CCGCCGCTCCGCAGCCACGCTCCAGCAGGAGAAGACAGACACGGTCCGCTGCATCAAGTCCTGCCGCCCCAACGATGTCACATGCGTGTT
CGACCCCGTGCACACCATCTCCCACACCGTCATCTCGCTGCCTACCTTCCGCGAGTTCACCCGCCCTGAAGAGATCATCTTCCTCCGGGC
CATCACGCCACCGCATCCTGCCAGCCAGGCTAACATCATCTTCGACATCACGGAAGGGAACCTGCGGGACTCTTTTGACATCATCAAGCG
TTACATGGACGGCATGACCGTGGGTGTCGTGCGCCAGGTGCGGCCCATCGTGGGCCCATTTCATGCCGTCCTGAAGCTGGAGATGAACTA
TGTGGTCGGGGGCGTGGTCTCCCACCGAAATGTTGTCAACGTCCACATCTTCGTCTCTGAGTACTGGTTCTGAGGGCTGGTCTGCCGCAC
AGCCGCAGGTGCACCTCCAGGCCAAATCATTGCTGCCAGTGACTGTGGTCTGTACTTGTTTATACCCTCAGACTTTTTTAATGTTAGGTA
TTTGTAGCATTAGGCCAACATGTATTAAGCTGAGCCAGATGAATAAGTCCATCTGATGTATTTTCGGTGTTTAAAAAATGAGCCCAGTTG
CTCAACTGTTTGGTTGAAAACCTTGCTCATTTTTTAATGCGAAGGCTAAGTGTCACCCCCTTTCTCTGCCTCTGGCTGGGCCTTGCTAAG
GGCCAAGGAAAGAAAGACATTTTTTAGGGGGCAGCCAGTCCAAATGCCAAAAGAAGACCAGTTCTTGCCCTGATTGTATGAAATTTGACA
TTTTGGCACTTTTTTTTTTTTTTTGGCCAATCAGATTTTCTATGTTCTAAGGACATGGCTGCTGTAGAATAGCACAGACGTGGATGATAA
ATTATCCCCAGAAGCAGCATGACAGAATGCCTCGGGGAGCACTTGGAAGGGAAATTGCAGTTCTGTTGAAATAGAGGAAAATCCCTTGGT
AAAGACACAGCCTGTTAGGCTCGTGTGGGCCTCCAGTATGTTCACCAGGGGAATGGCTGGGATTTCTCGGCACTCTGCATCATCCATCTT

>In-frame_ENST00000406733_ENST00000327858_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(amino acids)=393AA_start in transcript=241_stop in transcript=1422
MAPPGWGKTRLAVLGSRDSSGVSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAES
LNSEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGG
TSDPSTLSSSALSEREASRLDKFKQLLAGPNTDLDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIKS
CRPNDVTCVFDPVHTISHTVISLPTFREFTRPEEIIFLRAITPPHPASQANIIFDITEGNLRDSFDIIKRYMDGMTVGVVRQVRPIVGPF

--------------------------------------------------------------
>In-frame_ENST00000406733_ENST00000442170_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(transcript)=1826nt_BP=884nt
AGAAGTCTGTGCCCTTACCCATCACAGCCTCATCCTTATCTCCTCCATTCCCTAGGGGACTTAACAGGTGTTGAAATTATTACAGAGAAA
GCTGACTCACTCACCAGGAATCTGATCCTGCTGTGGGCTGGCTTGGGTGGAGGTGTTCCTCCCGCCCCCGCACCCATCCTCCTGTTTGAA
CTCAGGCTGCTGCCTGCTGGGCCTGCCTGCCCTTGGAGCCCTGCTGAGCTCAGCCTGAGGCCTGGCTCCTCCAGGCTGGGGGAAAACCAG
GCTTGCTGTGCTCGGCAGCAGAGATTCTTCTGGAGTGAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACA
TGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATAC
CAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGC
CAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGC
AGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAGTGCCAGCGA
TGCCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCTCAGCAGCTC
AGCGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGATGAGTGTGT
GACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGAGAACTA
CCGCCGCTCCGCAGCCACGCAGAAATCCAAGAAGGGAAGGCAGAACACCCCAGCGGGATCAAGTAAAGAGGACTGCAGGGTTCTTCCATG
GAAGCAGGGGTTGGAGGATACCCACCTTGATGCCTAGTGAGGAAGATGGACCTGGACAGACAGTCAGCTCCACACCTTGCGCTGAGCAGC
TGTGATTGTGCCACGGGAGCATGAGCCCTTTTCCCCACGGCCCTTGCCACTGTCTCCTGGCCCTCTCTCTGATCATGCCAGGTTTGCACC
AGCCTCGAGTCTCCCATGTTGTAGTACATTCTCCAAGATGCAGCCCAGGAGCCTCTCTGAAGGACCAGTCTGGTTACGATGGTCTGAGCT
TCCTTAGAACCTTCCATGGTTGTCTTTTCCCAGCAGATGAAGCATAGCCTCCTTGGAATGGCATGGGAGGCCTGGCCTGATCTGGCCTCT
GCCCACCCTTTGAGCTGCACCTGCCCCACCCCAGCTCATCCATGTGCTTGTACCCTGGCCCCACGGGGAGGCTTGCCCTTCCCTGAATCT
GCCTTCTTGTGGCTTTAGCATGTGCCATGCTGTCCCCCTGCAGACTGCCATTCTCCTTGCAGACTTGGCTCAGAAGTCACCTCCTCAGTG
CAGTTAGCCTGAGCTCCCCTGGCCCCAGGTGCCTCCATCAGAGCATTTACCCCATTGTGTTGTGGCTGTTCCTTAACGTCCCCACTAGCC
AGGCTCTTTGAGGGCAGGGATTGTGTCTGGTTAATTTCTGTATTCTCTGCAACTTTGCAATGTTTGGCTTGAAGAAGGAGCTCAGTAAAC

>In-frame_ENST00000406733_ENST00000442170_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(amino acids)=291AA_start in transcript=241_stop in transcript=1116
MAPPGWGKTRLAVLGSRDSSGVSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAES
LNSEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGG
TSDPSTLSSSALSEREASRLDKFKQLLAGPNTDLDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATQKSKKGRQNTPAGS

--------------------------------------------------------------
>In-frame_ENST00000406733_ENST00000340923_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(transcript)=1649nt_BP=884nt
AGAAGTCTGTGCCCTTACCCATCACAGCCTCATCCTTATCTCCTCCATTCCCTAGGGGACTTAACAGGTGTTGAAATTATTACAGAGAAA
GCTGACTCACTCACCAGGAATCTGATCCTGCTGTGGGCTGGCTTGGGTGGAGGTGTTCCTCCCGCCCCCGCACCCATCCTCCTGTTTGAA
CTCAGGCTGCTGCCTGCTGGGCCTGCCTGCCCTTGGAGCCCTGCTGAGCTCAGCCTGAGGCCTGGCTCCTCCAGGCTGGGGGAAAACCAG
GCTTGCTGTGCTCGGCAGCAGAGATTCTTCTGGAGTGAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACA
TGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATAC
CAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGC
CAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGC
AGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAGTGCCAGCGA
TGCCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCTCAGCAGCTC
AGCGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGATGAGTGTGT
GACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGAGAACTA
CCGCCGCTCCGCAGCCACATGATCGTAGGGAACTCTGCATGAGGCCATCGGTGCAGGCTGGAGAAGAGAAGGCAAGTTGGCAGGAGTGGA
GACCACGGGCATTTGAGCCACTTCCTCATGTAACTTAACTTGTGCCTTCAGGACCTGCTCAAGCCCGATCACGTATATACCACTTCCATT
TGATGATGGAATGCTGCTGTTCATGACCAACTTTATGGCTAGATGGGTCAGAAAGCACCCAGTTCATGATAGGCAGTTCAGGTCATATGG
TGACTTGATGACCCAGAGTCAAACATTCAGTTTCCACCAAAGCCCAGTAACAGGCCAAGAGCTGTCTCTCAAAAGGAGAGTAGTTATCTG
CAGAAGATGGCAGGGCCTTGCTCCGAAAGCCTAGAGACCGCCACTGTGATTCACCTATGGGGGCCTGCCAAAGGCTGCAGCCAGCATCCT
TATCTGCCACTGACACCTCAAGCAACATTGGATCTGCTGGGTCATATGGCCCAAGTGGCAGAGCAACTTGCACAACAGCCTGGACCTGTC
ATAGAGCTTTCTCCTGTTCTGGACCCCACTCAAAACTGGCAGCCTTTCAGGTCACTCGATAAATGTGCTGGAGTAACACTCAAACGAGGA

>In-frame_ENST00000406733_ENST00000340923_TCGA-85-A50M-01A_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946372_length(amino acids)=256AA_start in transcript=241_stop in transcript=1011
MAPPGWGKTRLAVLGSRDSSGVSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAES
LNSEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGG

--------------------------------------------------------------
>In-frame_ENST00000337137_ENST00000348697_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(transcript)=2030nt_BP=803nt
GCGCGTAGGCACAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCA
CAGGAAAGGGCCGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGG
GGCCAGGAAGCAATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCC
ACTGTTACATGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGA
GAGCAATACCAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCAT
GGAGACGGCCAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAG
GCCCGAGGCAGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAG
TGCCAGCGATGCCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCT
CAGCAGCTCAGCGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGA
TGAGTGTGTGACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCC
TGAGAACTACCGCCGCTCCGCAGCCACGCAGAAATCCAAGAAGGGAAGGCAGAACACCCCAGCGGGATCAAGTAAAGAGGACTGCAGGGT
TCTTCCATGGAAGCAGGGGTTGGAGGATACCCACCTTGATGCCTATCTCCCATGTTGCAGGAGATTCACCCGCCCTGAAGAGATCATCTT
CCTCCGGGCCATCACGCCACCGCATCCTGCCAGCCAGGCTAACATCATCTTCGACATCACGGAAGGGAACCTGCGGGACTCTTTTGACAT
CATCAAGCGTTACATGGACGGCATGACCGTGGGTGTCGTGCGCCAGGTGCGGCCCATCGTGGGCCCATTTCATGCCGTCCTGAAGCTGGA
GATGAACTATGTGGTCGGGGGCGTGGTCTCCCACCGAAATGTTGTCAACGTCCACATCTTCGTCTCTGAGTACTGGTTCTGAGGGCTGGT
CTGCCGCACAGCCGCAGGTGCACCTCCAGGCCAAATCATTGCTGCCAGTGACTGTGGTCTGTACTTGTTTATACCCTCAGACTTTTTTAA
TGTTAGGTATTTGTAGCATTAGGCCAACATGTATTAAGCTGAGCCAGATGAATAAGTCCATCTGATGTATTTTCGGTGTTTAAAAAATGA
GCCCAGTTGCTCAACTGTTTGGTTGAAAACCTTGCTCATTTTTTAATGCGAAGGCTAAGTGTCACCCCCTTTCTCTGCCTCTGGCTGGGC
CTTGCTAAGGGCCAAGGAAAGAAAGACATTTTTTAGGGGGCAGCCAGTCCAAATGCCAAAAGAAGACCAGTTCTTGCCCTGATTGTATGA
AATTTGACATTTTGGCACTTTTTTTTTTTTTTTGGCCAATCAGATTTTCTATGTTCTAAGGACATGGCTGCTGTAGAATAGCACAGACGT
GGATGATAAATTATCCCCAGAAGCAGCATGACAGAATGCCTCGGGGAGCACTTGGAAGGGAAATTGCAGTTCTGTTGAAATAGAGGAAAA
TCCCTTGGTAAAGACACAGCCTGTTAGGCTCGTGTGGGCCTCCAGTATGTTCACCAGGGGAATGGCTGGGATTTCTCGGCACTCTGCATC

>In-frame_ENST00000337137_ENST00000348697_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(amino acids)=391AA_start in transcript=166_stop in transcript=1341
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS
DPSTLSSSALSEREASRLDKFKQLLAGPNTDLDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATQKSKKGRQNTPAGSSK
EDCRVLPWKQGLEDTHLDAYLPCCRRFTRPEEIIFLRAITPPHPASQANIIFDITEGNLRDSFDIIKRYMDGMTVGVVRQVRPIVGPFHA

--------------------------------------------------------------
>In-frame_ENST00000337137_ENST00000402984_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(transcript)=1368nt_BP=803nt
GCGCGTAGGCACAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCA
CAGGAAAGGGCCGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGG
GGCCAGGAAGCAATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCC
ACTGTTACATGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGA
GAGCAATACCAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCAT
GGAGACGGCCAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAG
GCCCGAGGCAGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAG
TGCCAGCGATGCCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCT
CAGCAGCTCAGCGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGA
TGAGTGTGTGACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCC
TGAGAACTACCGCCGCTCCGCAGCCACCCGCTGTGAGCGCTTGCCTTGCCATGAGAATCGGGAGTGCTCCAAGCTGCCTCTGAGAATAAC
CTACTACCACCTCTCTTTCCCCACCAACATCCAAGCGCCCGCGGTGGTTTTCCGCATGGGCCCCTCCAGTGCTGTCCCCGGGGACAGCAT
GCAGCTGGCCATCACCGGCGGCAATGAGGAGGGCTTTTTCACCACCCGGAAGGTGAGCCCCCACAGTGGGGTGGTGGCCCTCACCAAGCC
TGTCCCCGAGCCCAGGGACTTGCTCCTGACCGTCAAGATGGATCTCTCTCGCCACGGCACCGTCAGCTCCTTTGTGGCCAAGCTTTTCAT
CTTTGTGTCTGCAGAGCTCTGAGCACTCGCTTCGCGTCGCGGGGTCTCCCTCCTGTTGCTTTCCTAACCCTGCCCTCCGGGGCGTTAATA

>In-frame_ENST00000337137_ENST00000402984_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(amino acids)=371AA_start in transcript=166_stop in transcript=1281
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS
DPSTLSSSALSEREASRLDKFKQLLAGPNTDLDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATRCERLPCHENRECSKL
PLRITYYHLSFPTNIQAPAVVFRMGPSSAVPGDSMQLAITGGNEEGFFTTRKVSPHSGVVALTKPVPEPRDLLLTVKMDLSRHGTVSSFV

--------------------------------------------------------------
>In-frame_ENST00000337137_ENST00000262722_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(transcript)=1378nt_BP=803nt
GCGCGTAGGCACAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCA
CAGGAAAGGGCCGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGG
GGCCAGGAAGCAATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCC
ACTGTTACATGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGA
GAGCAATACCAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCAT
GGAGACGGCCAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAG
GCCCGAGGCAGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAG
TGCCAGCGATGCCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCT
CAGCAGCTCAGCGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGA
TGAGTGTGTGACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCC
TGAGAACTACCGCCGCTCCGCAGCCACCCGCTGTGAGCGCTTGCCTTGCCATGAGAATCGGGAGTGCTCCAAGCTGCCTCTGAGAATAAC
CTACTACCACCTCTCTTTCCCCACCAACATCCAAGCGCCCGCGGTGGTTTTCCGCATGGGCCCCTCCAGTGCTGTCCCCGGGGACAGCAT
GCAGCTGGCCATCACCGGCGGCAATGAGGAGGGCTTTTTCACCACCCGGAAGGTGAGCCCCCACAGTGGGGTGGTGGCCCTCACCAAGCC
TGTCCCCGAGCCCAGGGACTTGCTCCTGACCGTCAAGATGGATCTCTCTCGCCACGGCACCGTCAGCTCCTTTGTGGCCAAGCTTTTCAT
CTTTGTGTCTGCAGAGCTCTGAGCACTCGCTTCGCGTCGCGGGGTCTCCCTCCTGTTGCTTTCCTAACCCTGCCCTCCGGGGCGTTAATA

>In-frame_ENST00000337137_ENST00000262722_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(amino acids)=371AA_start in transcript=166_stop in transcript=1281
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS
DPSTLSSSALSEREASRLDKFKQLLAGPNTDLDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATRCERLPCHENRECSKL
PLRITYYHLSFPTNIQAPAVVFRMGPSSAVPGDSMQLAITGGNEEGFFTTRKVSPHSGVVALTKPVPEPRDLLLTVKMDLSRHGTVSSFV

--------------------------------------------------------------
>In-frame_ENST00000337137_ENST00000327858_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(transcript)=2031nt_BP=803nt
GCGCGTAGGCACAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCA
CAGGAAAGGGCCGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGG
GGCCAGGAAGCAATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCC
ACTGTTACATGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGA
GAGCAATACCAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCAT
GGAGACGGCCAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAG
GCCCGAGGCAGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAG
TGCCAGCGATGCCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCT
CAGCAGCTCAGCGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGA
TGAGTGTGTGACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCC
TGAGAACTACCGCCGCTCCGCAGCCACGCTCCAGCAGGAGAAGACAGACACGGTCCGCTGCATCAAGTCCTGCCGCCCCAACGATGTCAC
ATGCGTGTTCGACCCCGTGCACACCATCTCCCACACCGTCATCTCGCTGCCTACCTTCCGCGAGTTCACCCGCCCTGAAGAGATCATCTT
CCTCCGGGCCATCACGCCACCGCATCCTGCCAGCCAGGCTAACATCATCTTCGACATCACGGAAGGGAACCTGCGGGACTCTTTTGACAT
CATCAAGCGTTACATGGACGGCATGACCGTGGGTGTCGTGCGCCAGGTGCGGCCCATCGTGGGCCCATTTCATGCCGTCCTGAAGCTGGA
GATGAACTATGTGGTCGGGGGCGTGGTCTCCCACCGAAATGTTGTCAACGTCCACATCTTCGTCTCTGAGTACTGGTTCTGAGGGCTGGT
CTGCCGCACAGCCGCAGGTGCACCTCCAGGCCAAATCATTGCTGCCAGTGACTGTGGTCTGTACTTGTTTATACCCTCAGACTTTTTTAA
TGTTAGGTATTTGTAGCATTAGGCCAACATGTATTAAGCTGAGCCAGATGAATAAGTCCATCTGATGTATTTTCGGTGTTTAAAAAATGA
GCCCAGTTGCTCAACTGTTTGGTTGAAAACCTTGCTCATTTTTTAATGCGAAGGCTAAGTGTCACCCCCTTTCTCTGCCTCTGGCTGGGC
CTTGCTAAGGGCCAAGGAAAGAAAGACATTTTTTAGGGGGCAGCCAGTCCAAATGCCAAAAGAAGACCAGTTCTTGCCCTGATTGTATGA
AATTTGACATTTTGGCACTTTTTTTTTTTTTTTGGCCAATCAGATTTTCTATGTTCTAAGGACATGGCTGCTGTAGAATAGCACAGACGT
GGATGATAAATTATCCCCAGAAGCAGCATGACAGAATGCCTCGGGGAGCACTTGGAAGGGAAATTGCAGTTCTGTTGAAATAGAGGAAAA
TCCCTTGGTAAAGACACAGCCTGTTAGGCTCGTGTGGGCCTCCAGTATGTTCACCAGGGGAATGGCTGGGATTTCTCGGCACTCTGCATC

>In-frame_ENST00000337137_ENST00000327858_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(amino acids)=391AA_start in transcript=166_stop in transcript=1341
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS
DPSTLSSSALSEREASRLDKFKQLLAGPNTDLDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIKSCR
PNDVTCVFDPVHTISHTVISLPTFREFTRPEEIIFLRAITPPHPASQANIIFDITEGNLRDSFDIIKRYMDGMTVGVVRQVRPIVGPFHA

--------------------------------------------------------------
>In-frame_ENST00000337137_ENST00000442170_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(transcript)=1745nt_BP=803nt
GCGCGTAGGCACAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCA
CAGGAAAGGGCCGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGG
GGCCAGGAAGCAATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCC
ACTGTTACATGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGA
GAGCAATACCAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCAT
GGAGACGGCCAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAG
GCCCGAGGCAGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAG
TGCCAGCGATGCCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCT
CAGCAGCTCAGCGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGA
TGAGTGTGTGACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCC
TGAGAACTACCGCCGCTCCGCAGCCACGCAGAAATCCAAGAAGGGAAGGCAGAACACCCCAGCGGGATCAAGTAAAGAGGACTGCAGGGT
TCTTCCATGGAAGCAGGGGTTGGAGGATACCCACCTTGATGCCTAGTGAGGAAGATGGACCTGGACAGACAGTCAGCTCCACACCTTGCG
CTGAGCAGCTGTGATTGTGCCACGGGAGCATGAGCCCTTTTCCCCACGGCCCTTGCCACTGTCTCCTGGCCCTCTCTCTGATCATGCCAG
GTTTGCACCAGCCTCGAGTCTCCCATGTTGTAGTACATTCTCCAAGATGCAGCCCAGGAGCCTCTCTGAAGGACCAGTCTGGTTACGATG
GTCTGAGCTTCCTTAGAACCTTCCATGGTTGTCTTTTCCCAGCAGATGAAGCATAGCCTCCTTGGAATGGCATGGGAGGCCTGGCCTGAT
CTGGCCTCTGCCCACCCTTTGAGCTGCACCTGCCCCACCCCAGCTCATCCATGTGCTTGTACCCTGGCCCCACGGGGAGGCTTGCCCTTC
CCTGAATCTGCCTTCTTGTGGCTTTAGCATGTGCCATGCTGTCCCCCTGCAGACTGCCATTCTCCTTGCAGACTTGGCTCAGAAGTCACC
TCCTCAGTGCAGTTAGCCTGAGCTCCCCTGGCCCCAGGTGCCTCCATCAGAGCATTTACCCCATTGTGTTGTGGCTGTTCCTTAACGTCC
CCACTAGCCAGGCTCTTTGAGGGCAGGGATTGTGTCTGGTTAATTTCTGTATTCTCTGCAACTTTGCAATGTTTGGCTTGAAGAAGGAGC

>In-frame_ENST00000337137_ENST00000442170_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(amino acids)=289AA_start in transcript=166_stop in transcript=1035
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS
DPSTLSSSALSEREASRLDKFKQLLAGPNTDLDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATQKSKKGRQNTPAGSSK

--------------------------------------------------------------
>In-frame_ENST00000337137_ENST00000340923_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(transcript)=1568nt_BP=803nt
GCGCGTAGGCACAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCA
CAGGAAAGGGCCGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGG
GGCCAGGAAGCAATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCC
ACTGTTACATGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGA
GAGCAATACCAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCAT
GGAGACGGCCAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAG
GCCCGAGGCAGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAG
TGCCAGCGATGCCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCT
CAGCAGCTCAGCGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGA
TGAGTGTGTGACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCC
TGAGAACTACCGCCGCTCCGCAGCCACATGATCGTAGGGAACTCTGCATGAGGCCATCGGTGCAGGCTGGAGAAGAGAAGGCAAGTTGGC
AGGAGTGGAGACCACGGGCATTTGAGCCACTTCCTCATGTAACTTAACTTGTGCCTTCAGGACCTGCTCAAGCCCGATCACGTATATACC
ACTTCCATTTGATGATGGAATGCTGCTGTTCATGACCAACTTTATGGCTAGATGGGTCAGAAAGCACCCAGTTCATGATAGGCAGTTCAG
GTCATATGGTGACTTGATGACCCAGAGTCAAACATTCAGTTTCCACCAAAGCCCAGTAACAGGCCAAGAGCTGTCTCTCAAAAGGAGAGT
AGTTATCTGCAGAAGATGGCAGGGCCTTGCTCCGAAAGCCTAGAGACCGCCACTGTGATTCACCTATGGGGGCCTGCCAAAGGCTGCAGC
CAGCATCCTTATCTGCCACTGACACCTCAAGCAACATTGGATCTGCTGGGTCATATGGCCCAAGTGGCAGAGCAACTTGCACAACAGCCT
GGACCTGTCATAGAGCTTTCTCCTGTTCTGGACCCCACTCAAAACTGGCAGCCTTTCAGGTCACTCGATAAATGTGCTGGAGTAACACTC

>In-frame_ENST00000337137_ENST00000340923_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(amino acids)=254AA_start in transcript=166_stop in transcript=930
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS

--------------------------------------------------------------
>In-frame_ENST00000380995_ENST00000348697_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(transcript)=2019nt_BP=792nt
CAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCACAGGAAAGGGC
CGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGGGGCCAGGAAGC
AATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACATG
GCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATACCA
GCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGCCA
ACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGCAG
AGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAGTGCCAGCGATG
CCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCTCAGCAGCTCAG
CGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGATGAGTGTGTGA
CTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGAGAACTACC
GCCGCTCCGCAGCCACGCAGAAATCCAAGAAGGGAAGGCAGAACACCCCAGCGGGATCAAGTAAAGAGGACTGCAGGGTTCTTCCATGGA
AGCAGGGGTTGGAGGATACCCACCTTGATGCCTATCTCCCATGTTGCAGGAGATTCACCCGCCCTGAAGAGATCATCTTCCTCCGGGCCA
TCACGCCACCGCATCCTGCCAGCCAGGCTAACATCATCTTCGACATCACGGAAGGGAACCTGCGGGACTCTTTTGACATCATCAAGCGTT
ACATGGACGGCATGACCGTGGGTGTCGTGCGCCAGGTGCGGCCCATCGTGGGCCCATTTCATGCCGTCCTGAAGCTGGAGATGAACTATG
TGGTCGGGGGCGTGGTCTCCCACCGAAATGTTGTCAACGTCCACATCTTCGTCTCTGAGTACTGGTTCTGAGGGCTGGTCTGCCGCACAG
CCGCAGGTGCACCTCCAGGCCAAATCATTGCTGCCAGTGACTGTGGTCTGTACTTGTTTATACCCTCAGACTTTTTTAATGTTAGGTATT
TGTAGCATTAGGCCAACATGTATTAAGCTGAGCCAGATGAATAAGTCCATCTGATGTATTTTCGGTGTTTAAAAAATGAGCCCAGTTGCT
CAACTGTTTGGTTGAAAACCTTGCTCATTTTTTAATGCGAAGGCTAAGTGTCACCCCCTTTCTCTGCCTCTGGCTGGGCCTTGCTAAGGG
CCAAGGAAAGAAAGACATTTTTTAGGGGGCAGCCAGTCCAAATGCCAAAAGAAGACCAGTTCTTGCCCTGATTGTATGAAATTTGACATT
TTGGCACTTTTTTTTTTTTTTTGGCCAATCAGATTTTCTATGTTCTAAGGACATGGCTGCTGTAGAATAGCACAGACGTGGATGATAAAT
TATCCCCAGAAGCAGCATGACAGAATGCCTCGGGGAGCACTTGGAAGGGAAATTGCAGTTCTGTTGAAATAGAGGAAAATCCCTTGGTAA
AGACACAGCCTGTTAGGCTCGTGTGGGCCTCCAGTATGTTCACCAGGGGAATGGCTGGGATTTCTCGGCACTCTGCATCATCCATCTTTT

>In-frame_ENST00000380995_ENST00000348697_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(amino acids)=391AA_start in transcript=155_stop in transcript=1330
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS
DPSTLSSSALSEREASRLDKFKQLLAGPNTDLDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATQKSKKGRQNTPAGSSK
EDCRVLPWKQGLEDTHLDAYLPCCRRFTRPEEIIFLRAITPPHPASQANIIFDITEGNLRDSFDIIKRYMDGMTVGVVRQVRPIVGPFHA

--------------------------------------------------------------
>In-frame_ENST00000380995_ENST00000402984_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(transcript)=1357nt_BP=792nt
CAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCACAGGAAAGGGC
CGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGGGGCCAGGAAGC
AATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACATG
GCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATACCA
GCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGCCA
ACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGCAG
AGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAGTGCCAGCGATG
CCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCTCAGCAGCTCAG
CGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGATGAGTGTGTGA
CTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGAGAACTACC
GCCGCTCCGCAGCCACCCGCTGTGAGCGCTTGCCTTGCCATGAGAATCGGGAGTGCTCCAAGCTGCCTCTGAGAATAACCTACTACCACC
TCTCTTTCCCCACCAACATCCAAGCGCCCGCGGTGGTTTTCCGCATGGGCCCCTCCAGTGCTGTCCCCGGGGACAGCATGCAGCTGGCCA
TCACCGGCGGCAATGAGGAGGGCTTTTTCACCACCCGGAAGGTGAGCCCCCACAGTGGGGTGGTGGCCCTCACCAAGCCTGTCCCCGAGC
CCAGGGACTTGCTCCTGACCGTCAAGATGGATCTCTCTCGCCACGGCACCGTCAGCTCCTTTGTGGCCAAGCTTTTCATCTTTGTGTCTG
CAGAGCTCTGAGCACTCGCTTCGCGTCGCGGGGTCTCCCTCCTGTTGCTTTCCTAACCCTGCCCTCCGGGGCGTTAATAAAGTCTTAGCA

>In-frame_ENST00000380995_ENST00000402984_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(amino acids)=371AA_start in transcript=155_stop in transcript=1270
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS
DPSTLSSSALSEREASRLDKFKQLLAGPNTDLDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATRCERLPCHENRECSKL
PLRITYYHLSFPTNIQAPAVVFRMGPSSAVPGDSMQLAITGGNEEGFFTTRKVSPHSGVVALTKPVPEPRDLLLTVKMDLSRHGTVSSFV

--------------------------------------------------------------
>In-frame_ENST00000380995_ENST00000262722_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(transcript)=1367nt_BP=792nt
CAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCACAGGAAAGGGC
CGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGGGGCCAGGAAGC
AATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACATG
GCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATACCA
GCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGCCA
ACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGCAG
AGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAGTGCCAGCGATG
CCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCTCAGCAGCTCAG
CGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGATGAGTGTGTGA
CTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGAGAACTACC
GCCGCTCCGCAGCCACCCGCTGTGAGCGCTTGCCTTGCCATGAGAATCGGGAGTGCTCCAAGCTGCCTCTGAGAATAACCTACTACCACC
TCTCTTTCCCCACCAACATCCAAGCGCCCGCGGTGGTTTTCCGCATGGGCCCCTCCAGTGCTGTCCCCGGGGACAGCATGCAGCTGGCCA
TCACCGGCGGCAATGAGGAGGGCTTTTTCACCACCCGGAAGGTGAGCCCCCACAGTGGGGTGGTGGCCCTCACCAAGCCTGTCCCCGAGC
CCAGGGACTTGCTCCTGACCGTCAAGATGGATCTCTCTCGCCACGGCACCGTCAGCTCCTTTGTGGCCAAGCTTTTCATCTTTGTGTCTG
CAGAGCTCTGAGCACTCGCTTCGCGTCGCGGGGTCTCCCTCCTGTTGCTTTCCTAACCCTGCCCTCCGGGGCGTTAATAAAGTCTTAGCA

>In-frame_ENST00000380995_ENST00000262722_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(amino acids)=371AA_start in transcript=155_stop in transcript=1270
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS
DPSTLSSSALSEREASRLDKFKQLLAGPNTDLDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATRCERLPCHENRECSKL
PLRITYYHLSFPTNIQAPAVVFRMGPSSAVPGDSMQLAITGGNEEGFFTTRKVSPHSGVVALTKPVPEPRDLLLTVKMDLSRHGTVSSFV

--------------------------------------------------------------
>In-frame_ENST00000380995_ENST00000327858_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(transcript)=2020nt_BP=792nt
CAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCACAGGAAAGGGC
CGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGGGGCCAGGAAGC
AATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACATG
GCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATACCA
GCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGCCA
ACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGCAG
AGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAGTGCCAGCGATG
CCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCTCAGCAGCTCAG
CGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGATGAGTGTGTGA
CTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGAGAACTACC
GCCGCTCCGCAGCCACGCTCCAGCAGGAGAAGACAGACACGGTCCGCTGCATCAAGTCCTGCCGCCCCAACGATGTCACATGCGTGTTCG
ACCCCGTGCACACCATCTCCCACACCGTCATCTCGCTGCCTACCTTCCGCGAGTTCACCCGCCCTGAAGAGATCATCTTCCTCCGGGCCA
TCACGCCACCGCATCCTGCCAGCCAGGCTAACATCATCTTCGACATCACGGAAGGGAACCTGCGGGACTCTTTTGACATCATCAAGCGTT
ACATGGACGGCATGACCGTGGGTGTCGTGCGCCAGGTGCGGCCCATCGTGGGCCCATTTCATGCCGTCCTGAAGCTGGAGATGAACTATG
TGGTCGGGGGCGTGGTCTCCCACCGAAATGTTGTCAACGTCCACATCTTCGTCTCTGAGTACTGGTTCTGAGGGCTGGTCTGCCGCACAG
CCGCAGGTGCACCTCCAGGCCAAATCATTGCTGCCAGTGACTGTGGTCTGTACTTGTTTATACCCTCAGACTTTTTTAATGTTAGGTATT
TGTAGCATTAGGCCAACATGTATTAAGCTGAGCCAGATGAATAAGTCCATCTGATGTATTTTCGGTGTTTAAAAAATGAGCCCAGTTGCT
CAACTGTTTGGTTGAAAACCTTGCTCATTTTTTAATGCGAAGGCTAAGTGTCACCCCCTTTCTCTGCCTCTGGCTGGGCCTTGCTAAGGG
CCAAGGAAAGAAAGACATTTTTTAGGGGGCAGCCAGTCCAAATGCCAAAAGAAGACCAGTTCTTGCCCTGATTGTATGAAATTTGACATT
TTGGCACTTTTTTTTTTTTTTTGGCCAATCAGATTTTCTATGTTCTAAGGACATGGCTGCTGTAGAATAGCACAGACGTGGATGATAAAT
TATCCCCAGAAGCAGCATGACAGAATGCCTCGGGGAGCACTTGGAAGGGAAATTGCAGTTCTGTTGAAATAGAGGAAAATCCCTTGGTAA
AGACACAGCCTGTTAGGCTCGTGTGGGCCTCCAGTATGTTCACCAGGGGAATGGCTGGGATTTCTCGGCACTCTGCATCATCCATCTTTT

>In-frame_ENST00000380995_ENST00000327858_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(amino acids)=391AA_start in transcript=155_stop in transcript=1330
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS
DPSTLSSSALSEREASRLDKFKQLLAGPNTDLDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIKSCR
PNDVTCVFDPVHTISHTVISLPTFREFTRPEEIIFLRAITPPHPASQANIIFDITEGNLRDSFDIIKRYMDGMTVGVVRQVRPIVGPFHA

--------------------------------------------------------------
>In-frame_ENST00000380995_ENST00000442170_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(transcript)=1734nt_BP=792nt
CAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCACAGGAAAGGGC
CGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGGGGCCAGGAAGC
AATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACATG
GCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATACCA
GCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGCCA
ACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGCAG
AGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAGTGCCAGCGATG
CCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCTCAGCAGCTCAG
CGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGATGAGTGTGTGA
CTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGAGAACTACC
GCCGCTCCGCAGCCACGCAGAAATCCAAGAAGGGAAGGCAGAACACCCCAGCGGGATCAAGTAAAGAGGACTGCAGGGTTCTTCCATGGA
AGCAGGGGTTGGAGGATACCCACCTTGATGCCTAGTGAGGAAGATGGACCTGGACAGACAGTCAGCTCCACACCTTGCGCTGAGCAGCTG
TGATTGTGCCACGGGAGCATGAGCCCTTTTCCCCACGGCCCTTGCCACTGTCTCCTGGCCCTCTCTCTGATCATGCCAGGTTTGCACCAG
CCTCGAGTCTCCCATGTTGTAGTACATTCTCCAAGATGCAGCCCAGGAGCCTCTCTGAAGGACCAGTCTGGTTACGATGGTCTGAGCTTC
CTTAGAACCTTCCATGGTTGTCTTTTCCCAGCAGATGAAGCATAGCCTCCTTGGAATGGCATGGGAGGCCTGGCCTGATCTGGCCTCTGC
CCACCCTTTGAGCTGCACCTGCCCCACCCCAGCTCATCCATGTGCTTGTACCCTGGCCCCACGGGGAGGCTTGCCCTTCCCTGAATCTGC
CTTCTTGTGGCTTTAGCATGTGCCATGCTGTCCCCCTGCAGACTGCCATTCTCCTTGCAGACTTGGCTCAGAAGTCACCTCCTCAGTGCA
GTTAGCCTGAGCTCCCCTGGCCCCAGGTGCCTCCATCAGAGCATTTACCCCATTGTGTTGTGGCTGTTCCTTAACGTCCCCACTAGCCAG
GCTCTTTGAGGGCAGGGATTGTGTCTGGTTAATTTCTGTATTCTCTGCAACTTTGCAATGTTTGGCTTGAAGAAGGAGCTCAGTAAACAT

>In-frame_ENST00000380995_ENST00000442170_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(amino acids)=289AA_start in transcript=155_stop in transcript=1024
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS
DPSTLSSSALSEREASRLDKFKQLLAGPNTDLDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATQKSKKGRQNTPAGSSK

--------------------------------------------------------------
>In-frame_ENST00000380995_ENST00000340923_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(transcript)=1557nt_BP=792nt
CAACTTCCGGAAGGAGGCGGAAGAGCTTCTCGGCTCTAGGCTCTGGAGTCCCGGGAGCAGTGAGGGGCCACCCGGGGCACAGGAAAGGGC
CGCTAGGGGAGGGCCGGGTGCACTCGGGGTGTCTGGGCCGCGGGTCTGAGGGATGAGGAGGGGCCATGGCCAGCGACGGGGCCAGGAAGC
AATTCTGGAAGCGCAGCAACAGCAAGCTCCCGGGCAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACATG
GCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATACCA
GCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGCCA
ACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGCAG
AGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAGTGCCAGCGATG
CCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCTCAGCAGCTCAG
CGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGATGAGTGTGTGA
CTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGAGAACTACC
GCCGCTCCGCAGCCACATGATCGTAGGGAACTCTGCATGAGGCCATCGGTGCAGGCTGGAGAAGAGAAGGCAAGTTGGCAGGAGTGGAGA
CCACGGGCATTTGAGCCACTTCCTCATGTAACTTAACTTGTGCCTTCAGGACCTGCTCAAGCCCGATCACGTATATACCACTTCCATTTG
ATGATGGAATGCTGCTGTTCATGACCAACTTTATGGCTAGATGGGTCAGAAAGCACCCAGTTCATGATAGGCAGTTCAGGTCATATGGTG
ACTTGATGACCCAGAGTCAAACATTCAGTTTCCACCAAAGCCCAGTAACAGGCCAAGAGCTGTCTCTCAAAAGGAGAGTAGTTATCTGCA
GAAGATGGCAGGGCCTTGCTCCGAAAGCCTAGAGACCGCCACTGTGATTCACCTATGGGGGCCTGCCAAAGGCTGCAGCCAGCATCCTTA
TCTGCCACTGACACCTCAAGCAACATTGGATCTGCTGGGTCATATGGCCCAAGTGGCAGAGCAACTTGCACAACAGCCTGGACCTGTCAT
AGAGCTTTCTCCTGTTCTGGACCCCACTCAAAACTGGCAGCCTTTCAGGTCACTCGATAAATGTGCTGGAGTAACACTCAAACGAGGAAT

>In-frame_ENST00000380995_ENST00000340923_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(amino acids)=254AA_start in transcript=155_stop in transcript=919
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLN
SEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS

--------------------------------------------------------------
>In-frame_ENST00000406733_ENST00000348697_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(transcript)=2111nt_BP=884nt
AGAAGTCTGTGCCCTTACCCATCACAGCCTCATCCTTATCTCCTCCATTCCCTAGGGGACTTAACAGGTGTTGAAATTATTACAGAGAAA
GCTGACTCACTCACCAGGAATCTGATCCTGCTGTGGGCTGGCTTGGGTGGAGGTGTTCCTCCCGCCCCCGCACCCATCCTCCTGTTTGAA
CTCAGGCTGCTGCCTGCTGGGCCTGCCTGCCCTTGGAGCCCTGCTGAGCTCAGCCTGAGGCCTGGCTCCTCCAGGCTGGGGGAAAACCAG
GCTTGCTGTGCTCGGCAGCAGAGATTCTTCTGGAGTGAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACA
TGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATAC
CAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGC
CAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGC
AGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAGTGCCAGCGA
TGCCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCTCAGCAGCTC
AGCGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGATGAGTGTGT
GACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGAGAACTA
CCGCCGCTCCGCAGCCACGCAGAAATCCAAGAAGGGAAGGCAGAACACCCCAGCGGGATCAAGTAAAGAGGACTGCAGGGTTCTTCCATG
GAAGCAGGGGTTGGAGGATACCCACCTTGATGCCTATCTCCCATGTTGCAGGAGATTCACCCGCCCTGAAGAGATCATCTTCCTCCGGGC
CATCACGCCACCGCATCCTGCCAGCCAGGCTAACATCATCTTCGACATCACGGAAGGGAACCTGCGGGACTCTTTTGACATCATCAAGCG
TTACATGGACGGCATGACCGTGGGTGTCGTGCGCCAGGTGCGGCCCATCGTGGGCCCATTTCATGCCGTCCTGAAGCTGGAGATGAACTA
TGTGGTCGGGGGCGTGGTCTCCCACCGAAATGTTGTCAACGTCCACATCTTCGTCTCTGAGTACTGGTTCTGAGGGCTGGTCTGCCGCAC
AGCCGCAGGTGCACCTCCAGGCCAAATCATTGCTGCCAGTGACTGTGGTCTGTACTTGTTTATACCCTCAGACTTTTTTAATGTTAGGTA
TTTGTAGCATTAGGCCAACATGTATTAAGCTGAGCCAGATGAATAAGTCCATCTGATGTATTTTCGGTGTTTAAAAAATGAGCCCAGTTG
CTCAACTGTTTGGTTGAAAACCTTGCTCATTTTTTAATGCGAAGGCTAAGTGTCACCCCCTTTCTCTGCCTCTGGCTGGGCCTTGCTAAG
GGCCAAGGAAAGAAAGACATTTTTTAGGGGGCAGCCAGTCCAAATGCCAAAAGAAGACCAGTTCTTGCCCTGATTGTATGAAATTTGACA
TTTTGGCACTTTTTTTTTTTTTTTGGCCAATCAGATTTTCTATGTTCTAAGGACATGGCTGCTGTAGAATAGCACAGACGTGGATGATAA
ATTATCCCCAGAAGCAGCATGACAGAATGCCTCGGGGAGCACTTGGAAGGGAAATTGCAGTTCTGTTGAAATAGAGGAAAATCCCTTGGT
AAAGACACAGCCTGTTAGGCTCGTGTGGGCCTCCAGTATGTTCACCAGGGGAATGGCTGGGATTTCTCGGCACTCTGCATCATCCATCTT

>In-frame_ENST00000406733_ENST00000348697_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(amino acids)=393AA_start in transcript=241_stop in transcript=1422
MAPPGWGKTRLAVLGSRDSSGVSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAES
LNSEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGG
TSDPSTLSSSALSEREASRLDKFKQLLAGPNTDLDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATQKSKKGRQNTPAGS
SKEDCRVLPWKQGLEDTHLDAYLPCCRRFTRPEEIIFLRAITPPHPASQANIIFDITEGNLRDSFDIIKRYMDGMTVGVVRQVRPIVGPF

--------------------------------------------------------------
>In-frame_ENST00000406733_ENST00000402984_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(transcript)=1449nt_BP=884nt
AGAAGTCTGTGCCCTTACCCATCACAGCCTCATCCTTATCTCCTCCATTCCCTAGGGGACTTAACAGGTGTTGAAATTATTACAGAGAAA
GCTGACTCACTCACCAGGAATCTGATCCTGCTGTGGGCTGGCTTGGGTGGAGGTGTTCCTCCCGCCCCCGCACCCATCCTCCTGTTTGAA
CTCAGGCTGCTGCCTGCTGGGCCTGCCTGCCCTTGGAGCCCTGCTGAGCTCAGCCTGAGGCCTGGCTCCTCCAGGCTGGGGGAAAACCAG
GCTTGCTGTGCTCGGCAGCAGAGATTCTTCTGGAGTGAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACA
TGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATAC
CAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGC
CAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGC
AGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAGTGCCAGCGA
TGCCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCTCAGCAGCTC
AGCGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGATGAGTGTGT
GACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGAGAACTA
CCGCCGCTCCGCAGCCACCCGCTGTGAGCGCTTGCCTTGCCATGAGAATCGGGAGTGCTCCAAGCTGCCTCTGAGAATAACCTACTACCA
CCTCTCTTTCCCCACCAACATCCAAGCGCCCGCGGTGGTTTTCCGCATGGGCCCCTCCAGTGCTGTCCCCGGGGACAGCATGCAGCTGGC
CATCACCGGCGGCAATGAGGAGGGCTTTTTCACCACCCGGAAGGTGAGCCCCCACAGTGGGGTGGTGGCCCTCACCAAGCCTGTCCCCGA
GCCCAGGGACTTGCTCCTGACCGTCAAGATGGATCTCTCTCGCCACGGCACCGTCAGCTCCTTTGTGGCCAAGCTTTTCATCTTTGTGTC
TGCAGAGCTCTGAGCACTCGCTTCGCGTCGCGGGGTCTCCCTCCTGTTGCTTTCCTAACCCTGCCCTCCGGGGCGTTAATAAAGTCTTAG

>In-frame_ENST00000406733_ENST00000402984_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(amino acids)=373AA_start in transcript=241_stop in transcript=1362
MAPPGWGKTRLAVLGSRDSSGVSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAES
LNSEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGG
TSDPSTLSSSALSEREASRLDKFKQLLAGPNTDLDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATRCERLPCHENRECS
KLPLRITYYHLSFPTNIQAPAVVFRMGPSSAVPGDSMQLAITGGNEEGFFTTRKVSPHSGVVALTKPVPEPRDLLLTVKMDLSRHGTVSS

--------------------------------------------------------------
>In-frame_ENST00000406733_ENST00000262722_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(transcript)=1459nt_BP=884nt
AGAAGTCTGTGCCCTTACCCATCACAGCCTCATCCTTATCTCCTCCATTCCCTAGGGGACTTAACAGGTGTTGAAATTATTACAGAGAAA
GCTGACTCACTCACCAGGAATCTGATCCTGCTGTGGGCTGGCTTGGGTGGAGGTGTTCCTCCCGCCCCCGCACCCATCCTCCTGTTTGAA
CTCAGGCTGCTGCCTGCTGGGCCTGCCTGCCCTTGGAGCCCTGCTGAGCTCAGCCTGAGGCCTGGCTCCTCCAGGCTGGGGGAAAACCAG
GCTTGCTGTGCTCGGCAGCAGAGATTCTTCTGGAGTGAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACA
TGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATAC
CAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGC
CAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGC
AGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAGTGCCAGCGA
TGCCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCTCAGCAGCTC
AGCGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGATGAGTGTGT
GACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGAGAACTA
CCGCCGCTCCGCAGCCACCCGCTGTGAGCGCTTGCCTTGCCATGAGAATCGGGAGTGCTCCAAGCTGCCTCTGAGAATAACCTACTACCA
CCTCTCTTTCCCCACCAACATCCAAGCGCCCGCGGTGGTTTTCCGCATGGGCCCCTCCAGTGCTGTCCCCGGGGACAGCATGCAGCTGGC
CATCACCGGCGGCAATGAGGAGGGCTTTTTCACCACCCGGAAGGTGAGCCCCCACAGTGGGGTGGTGGCCCTCACCAAGCCTGTCCCCGA
GCCCAGGGACTTGCTCCTGACCGTCAAGATGGATCTCTCTCGCCACGGCACCGTCAGCTCCTTTGTGGCCAAGCTTTTCATCTTTGTGTC
TGCAGAGCTCTGAGCACTCGCTTCGCGTCGCGGGGTCTCCCTCCTGTTGCTTTCCTAACCCTGCCCTCCGGGGCGTTAATAAAGTCTTAG

>In-frame_ENST00000406733_ENST00000262722_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(amino acids)=373AA_start in transcript=241_stop in transcript=1362
MAPPGWGKTRLAVLGSRDSSGVSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAES
LNSEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGG
TSDPSTLSSSALSEREASRLDKFKQLLAGPNTDLDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATRCERLPCHENRECS
KLPLRITYYHLSFPTNIQAPAVVFRMGPSSAVPGDSMQLAITGGNEEGFFTTRKVSPHSGVVALTKPVPEPRDLLLTVKMDLSRHGTVSS

--------------------------------------------------------------
>In-frame_ENST00000406733_ENST00000327858_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(transcript)=2112nt_BP=884nt
AGAAGTCTGTGCCCTTACCCATCACAGCCTCATCCTTATCTCCTCCATTCCCTAGGGGACTTAACAGGTGTTGAAATTATTACAGAGAAA
GCTGACTCACTCACCAGGAATCTGATCCTGCTGTGGGCTGGCTTGGGTGGAGGTGTTCCTCCCGCCCCCGCACCCATCCTCCTGTTTGAA
CTCAGGCTGCTGCCTGCTGGGCCTGCCTGCCCTTGGAGCCCTGCTGAGCTCAGCCTGAGGCCTGGCTCCTCCAGGCTGGGGGAAAACCAG
GCTTGCTGTGCTCGGCAGCAGAGATTCTTCTGGAGTGAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACA
TGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATAC
CAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGC
CAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGC
AGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAGTGCCAGCGA
TGCCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCTCAGCAGCTC
AGCGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGATGAGTGTGT
GACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGAGAACTA
CCGCCGCTCCGCAGCCACGCTCCAGCAGGAGAAGACAGACACGGTCCGCTGCATCAAGTCCTGCCGCCCCAACGATGTCACATGCGTGTT
CGACCCCGTGCACACCATCTCCCACACCGTCATCTCGCTGCCTACCTTCCGCGAGTTCACCCGCCCTGAAGAGATCATCTTCCTCCGGGC
CATCACGCCACCGCATCCTGCCAGCCAGGCTAACATCATCTTCGACATCACGGAAGGGAACCTGCGGGACTCTTTTGACATCATCAAGCG
TTACATGGACGGCATGACCGTGGGTGTCGTGCGCCAGGTGCGGCCCATCGTGGGCCCATTTCATGCCGTCCTGAAGCTGGAGATGAACTA
TGTGGTCGGGGGCGTGGTCTCCCACCGAAATGTTGTCAACGTCCACATCTTCGTCTCTGAGTACTGGTTCTGAGGGCTGGTCTGCCGCAC
AGCCGCAGGTGCACCTCCAGGCCAAATCATTGCTGCCAGTGACTGTGGTCTGTACTTGTTTATACCCTCAGACTTTTTTAATGTTAGGTA
TTTGTAGCATTAGGCCAACATGTATTAAGCTGAGCCAGATGAATAAGTCCATCTGATGTATTTTCGGTGTTTAAAAAATGAGCCCAGTTG
CTCAACTGTTTGGTTGAAAACCTTGCTCATTTTTTAATGCGAAGGCTAAGTGTCACCCCCTTTCTCTGCCTCTGGCTGGGCCTTGCTAAG
GGCCAAGGAAAGAAAGACATTTTTTAGGGGGCAGCCAGTCCAAATGCCAAAAGAAGACCAGTTCTTGCCCTGATTGTATGAAATTTGACA
TTTTGGCACTTTTTTTTTTTTTTTGGCCAATCAGATTTTCTATGTTCTAAGGACATGGCTGCTGTAGAATAGCACAGACGTGGATGATAA
ATTATCCCCAGAAGCAGCATGACAGAATGCCTCGGGGAGCACTTGGAAGGGAAATTGCAGTTCTGTTGAAATAGAGGAAAATCCCTTGGT
AAAGACACAGCCTGTTAGGCTCGTGTGGGCCTCCAGTATGTTCACCAGGGGAATGGCTGGGATTTCTCGGCACTCTGCATCATCCATCTT

>In-frame_ENST00000406733_ENST00000327858_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(amino acids)=393AA_start in transcript=241_stop in transcript=1422
MAPPGWGKTRLAVLGSRDSSGVSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAES
LNSEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGG
TSDPSTLSSSALSEREASRLDKFKQLLAGPNTDLDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIKS
CRPNDVTCVFDPVHTISHTVISLPTFREFTRPEEIIFLRAITPPHPASQANIIFDITEGNLRDSFDIIKRYMDGMTVGVVRQVRPIVGPF

--------------------------------------------------------------
>In-frame_ENST00000406733_ENST00000442170_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(transcript)=1826nt_BP=884nt
AGAAGTCTGTGCCCTTACCCATCACAGCCTCATCCTTATCTCCTCCATTCCCTAGGGGACTTAACAGGTGTTGAAATTATTACAGAGAAA
GCTGACTCACTCACCAGGAATCTGATCCTGCTGTGGGCTGGCTTGGGTGGAGGTGTTCCTCCCGCCCCCGCACCCATCCTCCTGTTTGAA
CTCAGGCTGCTGCCTGCTGGGCCTGCCTGCCCTTGGAGCCCTGCTGAGCTCAGCCTGAGGCCTGGCTCCTCCAGGCTGGGGGAAAACCAG
GCTTGCTGTGCTCGGCAGCAGAGATTCTTCTGGAGTGAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACA
TGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATAC
CAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGC
CAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGC
AGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAGTGCCAGCGA
TGCCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCTCAGCAGCTC
AGCGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGATGAGTGTGT
GACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGAGAACTA
CCGCCGCTCCGCAGCCACGCAGAAATCCAAGAAGGGAAGGCAGAACACCCCAGCGGGATCAAGTAAAGAGGACTGCAGGGTTCTTCCATG
GAAGCAGGGGTTGGAGGATACCCACCTTGATGCCTAGTGAGGAAGATGGACCTGGACAGACAGTCAGCTCCACACCTTGCGCTGAGCAGC
TGTGATTGTGCCACGGGAGCATGAGCCCTTTTCCCCACGGCCCTTGCCACTGTCTCCTGGCCCTCTCTCTGATCATGCCAGGTTTGCACC
AGCCTCGAGTCTCCCATGTTGTAGTACATTCTCCAAGATGCAGCCCAGGAGCCTCTCTGAAGGACCAGTCTGGTTACGATGGTCTGAGCT
TCCTTAGAACCTTCCATGGTTGTCTTTTCCCAGCAGATGAAGCATAGCCTCCTTGGAATGGCATGGGAGGCCTGGCCTGATCTGGCCTCT
GCCCACCCTTTGAGCTGCACCTGCCCCACCCCAGCTCATCCATGTGCTTGTACCCTGGCCCCACGGGGAGGCTTGCCCTTCCCTGAATCT
GCCTTCTTGTGGCTTTAGCATGTGCCATGCTGTCCCCCTGCAGACTGCCATTCTCCTTGCAGACTTGGCTCAGAAGTCACCTCCTCAGTG
CAGTTAGCCTGAGCTCCCCTGGCCCCAGGTGCCTCCATCAGAGCATTTACCCCATTGTGTTGTGGCTGTTCCTTAACGTCCCCACTAGCC
AGGCTCTTTGAGGGCAGGGATTGTGTCTGGTTAATTTCTGTATTCTCTGCAACTTTGCAATGTTTGGCTTGAAGAAGGAGCTCAGTAAAC

>In-frame_ENST00000406733_ENST00000442170_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(amino acids)=291AA_start in transcript=241_stop in transcript=1116
MAPPGWGKTRLAVLGSRDSSGVSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAES
LNSEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGG
TSDPSTLSSSALSEREASRLDKFKQLLAGPNTDLDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATQKSKKGRQNTPAGS

--------------------------------------------------------------
>In-frame_ENST00000406733_ENST00000340923_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(transcript)=1649nt_BP=884nt
AGAAGTCTGTGCCCTTACCCATCACAGCCTCATCCTTATCTCCTCCATTCCCTAGGGGACTTAACAGGTGTTGAAATTATTACAGAGAAA
GCTGACTCACTCACCAGGAATCTGATCCTGCTGTGGGCTGGCTTGGGTGGAGGTGTTCCTCCCGCCCCCGCACCCATCCTCCTGTTTGAA
CTCAGGCTGCTGCCTGCTGGGCCTGCCTGCCCTTGGAGCCCTGCTGAGCTCAGCCTGAGGCCTGGCTCCTCCAGGCTGGGGGAAAACCAG
GCTTGCTGTGCTCGGCAGCAGAGATTCTTCTGGAGTGAGCATCCAGCACGTGTATGGTGCCCAGCACCCCCCCTTTGATCCACTGTTACA
TGGCACTTTGCTCAGGTCCACGGCCAAGATGCCGACCACACCAGTGAAGGCCAAGAGGGTCAGCACCTTCCAGGAGTTTGAGAGCAATAC
CAGCGATGCCTGGGACGCTGGGGAGGACGACGATGAGCTCCTGGCCATGGCGGCGGAGAGCCTGAACTCCGAGGTGGTCATGGAGACGGC
CAACCGTGTGCTGCGTAACCACAGCCAGCGGCAGGGGCGGCCCACGCTGCAGGAGGGGCCAGGGCTTCAGCAGAAGCCCAGGCCCGAGGC
AGAGCCGCCCTCACCCCCCAGCGGCGACCTCCGGCTGGTGAAGTCGGTCAGTGAGAGCCACACGTCCTGTCCTGCAGAAAGTGCCAGCGA
TGCCGCCCCTCTGCAGAGGTCCCAGTCTCTCCCACACTCGGCCACCGTCACGCTGGGTGGCACATCTGACCCCAGCACTCTCAGCAGCTC
AGCGCTGAGCGAAAGAGAGGCCTCCCGGCTCGACAAGTTCAAGCAGCTGCTTGCCGGCCCCAACACGGACCTTGACATTGATGAGTGTGT
GACTGGCATCCACAACTGCTCCATCAACGAGACCTGCTTCAACATCCAGGGCGGCTTCCGCTGCCTGGCCTTCGAGTGCCCTGAGAACTA
CCGCCGCTCCGCAGCCACATGATCGTAGGGAACTCTGCATGAGGCCATCGGTGCAGGCTGGAGAAGAGAAGGCAAGTTGGCAGGAGTGGA
GACCACGGGCATTTGAGCCACTTCCTCATGTAACTTAACTTGTGCCTTCAGGACCTGCTCAAGCCCGATCACGTATATACCACTTCCATT
TGATGATGGAATGCTGCTGTTCATGACCAACTTTATGGCTAGATGGGTCAGAAAGCACCCAGTTCATGATAGGCAGTTCAGGTCATATGG
TGACTTGATGACCCAGAGTCAAACATTCAGTTTCCACCAAAGCCCAGTAACAGGCCAAGAGCTGTCTCTCAAAAGGAGAGTAGTTATCTG
CAGAAGATGGCAGGGCCTTGCTCCGAAAGCCTAGAGACCGCCACTGTGATTCACCTATGGGGGCCTGCCAAAGGCTGCAGCCAGCATCCT
TATCTGCCACTGACACCTCAAGCAACATTGGATCTGCTGGGTCATATGGCCCAAGTGGCAGAGCAACTTGCACAACAGCCTGGACCTGTC
ATAGAGCTTTCTCCTGTTCTGGACCCCACTCAAAACTGGCAGCCTTTCAGGTCACTCGATAAATGTGCTGGAGTAACACTCAAACGAGGA

>In-frame_ENST00000406733_ENST00000340923_TCGA-85-A50M_TBC1D22A_chr22_47193517_+_FBLN1_chr22_45946371_length(amino acids)=256AA_start in transcript=241_stop in transcript=1011
MAPPGWGKTRLAVLGSRDSSGVSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAES
LNSEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for TBC1D22A-FBLN1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TBC1D22A-FBLN1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TBC1D22A-FBLN1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneFBLN1C1842422Synpolydactyly 23CTD_human;GENOMICS_ENGLAND;ORPHANET
TgeneFBLN1C0014175Endometriosis1CTD_human
TgeneFBLN1C0033578Prostatic Neoplasms1CTD_human
TgeneFBLN1C0269102Endometrioma1CTD_human
TgeneFBLN1C0376358Malignant neoplasm of prostate1CTD_human