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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TEAD1-PARVA (FusionGDB2 ID:89339)

Fusion Gene Summary for TEAD1-PARVA

check button Fusion gene summary
Fusion gene informationFusion gene name: TEAD1-PARVA
Fusion gene ID: 89339
HgeneTgene
Gene symbol

TEAD1

PARVA

Gene ID

7003

55742

Gene nameTEA domain transcription factor 1parvin alpha
SynonymsAA|NTEF-1|REF1|TCF-13|TCF13|TEAD-1|TEF-1CH-ILKBP|MXRA2
Cytomap

11p15.3

11p15.3

Type of geneprotein-codingprotein-coding
Descriptiontranscriptional enhancer factor TEF-1TEA domain family member 1 (SV40 transcriptional enhancer factor)protein GT-IICtranscription factor 13transcriptional enhancer factor 1alpha-parvinactopaxincalponin-like integrin-linked kinase-binding proteinmatrix-remodeling-associated protein 2
Modification date2020032920200313
UniProtAcc.

PVALB

Ensembl transtripts involved in fusion geneENST00000361905, ENST00000527636, 
ENST00000527575, ENST00000334310, 
ENST00000361985, ENST00000526600, 
ENST00000334956, ENST00000539723, 
ENST00000550549, ENST00000538608, 
ENST00000526746, 
Fusion gene scores* DoF score19 X 11 X 12=250813 X 10 X 8=1040
# samples 2315
** MAII scorelog2(23/2508*10)=-3.44683158185766
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/1040*10)=-2.79354912253257
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TEAD1 [Title/Abstract] AND PARVA [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTEAD1(12697108)-PARVA(12495292), # samples:3
Anticipated loss of major functional domain due to fusion event.TEAD1-PARVA seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
TEAD1-PARVA seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
TEAD1-PARVA seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneTEAD1

GO:0035329

hippo signaling

18579750|19324877


check buttonFusion gene breakpoints across TEAD1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across PARVA (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-E7-A85H-01ATEAD1chr11

12785981

+PARVAchr11

12549396

+
ChimerDB4BRCATCGA-E2-A15E-06ATEAD1chr11

12697108

+PARVAchr11

12495292

+
ChimerDB4BRCATCGA-E2-A15E-01ATEAD1chr11

12697108

-PARVAchr11

12495292

+
ChimerDB4BRCATCGA-E2-A15E-06ATEAD1chr11

12697108

-PARVAchr11

12495292

+
ChimerDB4BLCATCGA-E7-A85H-01ATEAD1chr11

12785981

-PARVAchr11

12549396

+


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Fusion Gene ORF analysis for TEAD1-PARVA

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000361905ENST00000334956TEAD1chr11

12785981

+PARVAchr11

12549396

+
Frame-shiftENST00000361905ENST00000539723TEAD1chr11

12785981

+PARVAchr11

12549396

+
Frame-shiftENST00000361905ENST00000550549TEAD1chr11

12785981

+PARVAchr11

12549396

+
5CDS-intronENST00000361905ENST00000538608TEAD1chr11

12785981

+PARVAchr11

12549396

+
5CDS-intronENST00000361905ENST00000526746TEAD1chr11

12785981

+PARVAchr11

12549396

+
In-frameENST00000527636ENST00000334956TEAD1chr11

12785981

+PARVAchr11

12549396

+
Frame-shiftENST00000527636ENST00000539723TEAD1chr11

12785981

+PARVAchr11

12549396

+
Frame-shiftENST00000527636ENST00000550549TEAD1chr11

12785981

+PARVAchr11

12549396

+
5CDS-intronENST00000527636ENST00000538608TEAD1chr11

12785981

+PARVAchr11

12549396

+
5CDS-intronENST00000527636ENST00000526746TEAD1chr11

12785981

+PARVAchr11

12549396

+
In-frameENST00000527575ENST00000334956TEAD1chr11

12785981

+PARVAchr11

12549396

+
Frame-shiftENST00000527575ENST00000539723TEAD1chr11

12785981

+PARVAchr11

12549396

+
Frame-shiftENST00000527575ENST00000550549TEAD1chr11

12785981

+PARVAchr11

12549396

+
5CDS-intronENST00000527575ENST00000538608TEAD1chr11

12785981

+PARVAchr11

12549396

+
5CDS-intronENST00000527575ENST00000526746TEAD1chr11

12785981

+PARVAchr11

12549396

+
In-frameENST00000334310ENST00000334956TEAD1chr11

12785981

+PARVAchr11

12549396

+
Frame-shiftENST00000334310ENST00000539723TEAD1chr11

12785981

+PARVAchr11

12549396

+
Frame-shiftENST00000334310ENST00000550549TEAD1chr11

12785981

+PARVAchr11

12549396

+
5CDS-intronENST00000334310ENST00000538608TEAD1chr11

12785981

+PARVAchr11

12549396

+
5CDS-intronENST00000334310ENST00000526746TEAD1chr11

12785981

+PARVAchr11

12549396

+
In-frameENST00000361985ENST00000334956TEAD1chr11

12785981

+PARVAchr11

12549396

+
Frame-shiftENST00000361985ENST00000539723TEAD1chr11

12785981

+PARVAchr11

12549396

+
Frame-shiftENST00000361985ENST00000550549TEAD1chr11

12785981

+PARVAchr11

12549396

+
5CDS-intronENST00000361985ENST00000538608TEAD1chr11

12785981

+PARVAchr11

12549396

+
5CDS-intronENST00000361985ENST00000526746TEAD1chr11

12785981

+PARVAchr11

12549396

+
intron-3CDSENST00000526600ENST00000334956TEAD1chr11

12785981

+PARVAchr11

12549396

+
intron-3CDSENST00000526600ENST00000539723TEAD1chr11

12785981

+PARVAchr11

12549396

+
intron-3CDSENST00000526600ENST00000550549TEAD1chr11

12785981

+PARVAchr11

12549396

+
intron-intronENST00000526600ENST00000538608TEAD1chr11

12785981

+PARVAchr11

12549396

+
intron-intronENST00000526600ENST00000526746TEAD1chr11

12785981

+PARVAchr11

12549396

+
5UTR-3CDSENST00000361905ENST00000334956TEAD1chr11

12697108

+PARVAchr11

12495292

+
5UTR-3CDSENST00000361905ENST00000539723TEAD1chr11

12697108

+PARVAchr11

12495292

+
5UTR-3CDSENST00000361905ENST00000550549TEAD1chr11

12697108

+PARVAchr11

12495292

+
5UTR-5UTRENST00000361905ENST00000538608TEAD1chr11

12697108

+PARVAchr11

12495292

+
5UTR-5UTRENST00000361905ENST00000526746TEAD1chr11

12697108

+PARVAchr11

12495292

+
5UTR-3CDSENST00000527636ENST00000334956TEAD1chr11

12697108

+PARVAchr11

12495292

+
5UTR-3CDSENST00000527636ENST00000539723TEAD1chr11

12697108

+PARVAchr11

12495292

+
5UTR-3CDSENST00000527636ENST00000550549TEAD1chr11

12697108

+PARVAchr11

12495292

+
5UTR-5UTRENST00000527636ENST00000538608TEAD1chr11

12697108

+PARVAchr11

12495292

+
5UTR-5UTRENST00000527636ENST00000526746TEAD1chr11

12697108

+PARVAchr11

12495292

+
5UTR-3CDSENST00000527575ENST00000334956TEAD1chr11

12697108

+PARVAchr11

12495292

+
5UTR-3CDSENST00000527575ENST00000539723TEAD1chr11

12697108

+PARVAchr11

12495292

+
5UTR-3CDSENST00000527575ENST00000550549TEAD1chr11

12697108

+PARVAchr11

12495292

+
5UTR-5UTRENST00000527575ENST00000538608TEAD1chr11

12697108

+PARVAchr11

12495292

+
5UTR-5UTRENST00000527575ENST00000526746TEAD1chr11

12697108

+PARVAchr11

12495292

+
5UTR-3CDSENST00000334310ENST00000334956TEAD1chr11

12697108

+PARVAchr11

12495292

+
5UTR-3CDSENST00000334310ENST00000539723TEAD1chr11

12697108

+PARVAchr11

12495292

+
5UTR-3CDSENST00000334310ENST00000550549TEAD1chr11

12697108

+PARVAchr11

12495292

+
5UTR-5UTRENST00000334310ENST00000538608TEAD1chr11

12697108

+PARVAchr11

12495292

+
5UTR-5UTRENST00000334310ENST00000526746TEAD1chr11

12697108

+PARVAchr11

12495292

+
intron-3CDSENST00000361985ENST00000334956TEAD1chr11

12697108

+PARVAchr11

12495292

+
intron-3CDSENST00000361985ENST00000539723TEAD1chr11

12697108

+PARVAchr11

12495292

+
intron-3CDSENST00000361985ENST00000550549TEAD1chr11

12697108

+PARVAchr11

12495292

+
intron-5UTRENST00000361985ENST00000538608TEAD1chr11

12697108

+PARVAchr11

12495292

+
intron-5UTRENST00000361985ENST00000526746TEAD1chr11

12697108

+PARVAchr11

12495292

+
intron-3CDSENST00000526600ENST00000334956TEAD1chr11

12697108

+PARVAchr11

12495292

+
intron-3CDSENST00000526600ENST00000539723TEAD1chr11

12697108

+PARVAchr11

12495292

+
intron-3CDSENST00000526600ENST00000550549TEAD1chr11

12697108

+PARVAchr11

12495292

+
intron-5UTRENST00000526600ENST00000538608TEAD1chr11

12697108

+PARVAchr11

12495292

+
intron-5UTRENST00000526600ENST00000526746TEAD1chr11

12697108

+PARVAchr11

12495292

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000361905TEAD1chr1112785981+ENST00000334956PARVAchr1112549396+37758225281176
ENST00000527636TEAD1chr1112785981+ENST00000334956PARVAchr1112549396+36066533590120
ENST00000527575TEAD1chr1112785981+ENST00000334956PARVAchr1112549396+326831535391118
ENST00000334310TEAD1chr1112785981+ENST00000334956PARVAchr1112549396+326831535391118
ENST00000361985TEAD1chr1112785981+ENST00000334956PARVAchr1112549396+330935613343299

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000361905ENST00000334956TEAD1chr1112785981+PARVAchr1112549396+0.071426140.92857385
ENST00000527636ENST00000334956TEAD1chr1112785981+PARVAchr1112549396+0.078154770.9218452
ENST00000527575ENST00000334956TEAD1chr1112785981+PARVAchr1112549396+0.089535340.91046464
ENST00000334310ENST00000334956TEAD1chr1112785981+PARVAchr1112549396+0.089535340.91046464
ENST00000361985ENST00000334956TEAD1chr1112785981+PARVAchr1112549396+0.0854643960.9145356

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Fusion Genomic Features for TEAD1-PARVA


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
TEAD1chr1112785981+PARVAchr1112549395+0.0097641190.99023587
TEAD1chr1112697108+PARVAchr1112495290+0.0001564340.9998436
TEAD1chr1112785981+PARVAchr1112549395+0.0097641190.99023587
TEAD1chr1112697108+PARVAchr1112495290+0.0001564340.9998436

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TEAD1-PARVA


check button Go to

FGviewer for the breakpoints of chr11:12785981-chr11:12549396

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.PARVA

PVALB

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.110

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTEAD1chr11:12785981chr11:12549396ENST00000361905+313143_20452.333333333333336412.0Compositional biasNote=Pro-rich
HgeneTEAD1chr11:12785981chr11:12549396ENST00000361905+313306_32852.333333333333336412.0Compositional biasNote=Ser/Thr/Tyr-rich
HgeneTEAD1chr11:12785981chr11:12549396ENST00000361905+31328_10452.333333333333336412.0DNA bindingTEA
HgeneTEAD1chr11:12785981chr11:12549396ENST00000361905+313167_42652.333333333333336412.0RegionTranscriptional activation
TgenePARVAchr11:12785981chr11:12549396ENST000005505491113262_369347.3333333333333373.0DomainCalponin-homology (CH) 2
TgenePARVAchr11:12785981chr11:12549396ENST00000550549111395_202347.3333333333333373.0DomainCalponin-homology (CH) 1


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Fusion Gene Sequence for TEAD1-PARVA


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000361905_ENST00000334956_TCGA-E7-A85H-01A_TEAD1_chr11_12785981_+_PARVA_chr11_12549396_length(transcript)=3775nt_BP=822nt
TTCCGAACATTCTTAGCATCGCTCGCGCCGCGCCGCGCCGCCTGAGCCGAGCCGAGCCTCTGCTGCCGCCGCCGCGGCCCCGCCGCCCGC
CGCGGGCGCCCACCAAGCACTTTGCAGACTCGCTTCCACCCTGCGGGCCATTCCGCGCGGCGGGGCCCGGGCCCGGGGCGGCCGCGTCCA
GGCACAGGCCATGCAGTGACGCCCCCCCACCCCTCCACCTTTGCCCGGAGCGCGGGCAGCAGCCCAGCGCGCCAGCCGGCCCCGGGGCAG
GAGCGGTGCTAGGCAGGGGTGGGGTGGCCGGGCCCAGGGACCGGGAGCCGGGGAGGGAGCCGGGCACCGAGCAGAGGGCGGGGGAAGCGG
CGCCGAAGTTTGCCTCGGACTCGCCGGGCGCTGCGGTGGCTCCCTGGGCCGAGGACTGTTGCTGCCGCTGCCGCCGCCGCTTCATTGCAC
ATTCAAGTGGAAAATTTTCAGGAGTCAGCAGAAACATTGTGTCCAAAAAAGACTGAGTCGCAGTTACCACCAAACCCAGGAGGAGACTCT
CCCTGGAAAACTTCCCTTCCCTTTCGGTTTATTTTCTTGAAAAGGCTCCAGGCTTCGGCTTGGAAAATCCCACCGCCAAAATTGAGCCCA
GCAGCTGGAGCGGCAGTGAGAGCCCTGCCGAAAACATGGAAAGGATGAGTGACTCTGCAGATAAGCCAATTGACAATGATGCAGAAGGGG
TCTGGAGCCCCGACATCGAGCAAAGCTTTCAGGAGGCCCTGGCTATCTATCCACCATGTGGGAGGAGGAAAATCATCTTATCAGACGAAG
GCAAAATGTATGACATAGTCAACTGTGACCTGAAATCTACACTACGAGTGTTGTACAACCTCTTCACCAAGTACCGTAACGTGGAGTGAG
GGGCTGCCCTGGGCCCACCACTGCCCAAGAGTTCTTGCTGTTGGCGTACTGGACCCTCCTCCGAACTGCCTTACCCTGCTTATTCCTGTC
TCTTGCACTGTGCTCTCCCACAAGTCCAGCTGCAACCCAGAGATAGTGGAAACTGAAATTAGGAAGGAAATCATCAATAACTCAGTGGGC
TGACCCATCCCTCCCAGGCGCTGGGGACCAACCTAGCAATGAAGGTTGGGAAGGTTGTTCCCTTCCCGGTGCCAGGTCCAGATTTCCCTC
CATGATTTGGGAACCAGCTTAGGCAAAAGAGTCCCCACAAGATGAAAATAAAGATCCTAGTTACCATTCAAAGGATGCTAACTGTGTGTC
AGGCCCCACACTAAGTGCTCTGCTCTGATATACTCAAGGCCATTAATCTTCAGGACTCCCATTGACGTAGGTGTTTCATTCCCCTTTTAC
AGATGAGGAAACTAAGGCTTGGAGGTTAAATGACTTGCCAGAAGTTGGAATTTTTTTCCTCTTTGAACATAACCTCTCCCTTCTCCCTAA
AGGTAACCACTATTCTGAGTCCAATCATCAAGGTTTTGCTTTTCTTTTTAGCTAAGTATGCATTCCTCAATAGTAGACAGTACAACATGT
TTATAACAAGCCAATTACATTATGTTCTTTGCATGTTCTAAAGTTGTGTATGTGTGTGCACATCTGAGCACGTGCACATGTACACCTGAG
CCAAAAACACGAGAACCCACTGATCTCACCACTGGGGCAAGCTAGGTCAGAGCTTAGTGATTCACACTGAAATTGGCAAATTGGATTTAA
CCCAATTAATAGTGTGTGTGTGGCAGGAGTCATGTCCCTCACATCCTTTGTACAAATGAAAATTACTCTTAATTCCTTCAGATTTATAAT
AACTCTGTACTTTGGTTTCAGGGTGACATTTGGGAAGGATTTTGTTTAGAATTAATGGAGTGGCACATTTTGCAGCCTTTTTGCTTGATT
GCATGTAATGGAAATGCCCTATATTTTCCTGCAAAATAAGTACTAAATTCATTATCGTTAAGCAAATGTACAATATGCTCAGGCACCGCA
GAGAGCTGGGCACGGGCCCATGTGAGCATCACTTTGGAAGTAGGGCTCTTCAACAGGGACCCTTGAACTTTAAAGAAAGGAACTTCTTTT
TGCCTTCTAATTGATCATTTAGACTATTCTGGCTAAGTCTGCCCACATGTAATTACCGGCTAATTCAAGCGAGGAAAAATGTAAGTCATT
TAGACCAAAGCCAAGCAGTTTCTTTGCGTGGGTTACTCAAGGGCTTGTGGTTACTTGTATCTCCTCTATGTGAACTTGACTTTGAAAGAC
AGAGCTCTAGTGTGCCAGCCTGCTAAGTCCTGTAAGAATAGGGAAGGGCGGAGGGGGGTGGGCAGTGACTAGGGGACGAGAAGCATGGGG
AAAATATTTGCACTCTAAACATACAGAGATAGAGGTGGGGCTTGTGGTACTTAACACTTGTAGCCATCAACTGACTGAGACCTTGGGCTA
AATAATCAATTGTGCTGATATTACATCTCGTTATGGAATGTTCCTAAATATGCCAGGTAGACACCAGCCCAAGTACCCTCCTCCAGAAGT
CTGTGACTACCTTGTCACTACTTTAGGCCCATTCCACAAAGCCCATCTCTGGTTTGAGAATTCATTTTGATCTGTATCTACACCACCCAA
AGTTAGGCCTCCTATAATGTCCAAAACATTCCTTTCAGCCTTTTTATTTCTTACTGTACTGTCTCTTACTGTACTGTCTATCTGCAGTAA
TTGAGGACCCATAAAATTTAGATAACTACATGTCTTTGCTCTTAGAATTGTCACTCAGCATAATGAGCATTTAACATACAAAGGCAATGT
ACTGTTTTGTGTTGATCTATGTAAAAGAATACAATTCTTTTTTACATAATTAGTGAAATTTTATTTTTTATTAGGAAACACTAAATAGTG
TAATATTTCTTTTGCTTTTAAAAAAATTCCTGGTAGCAAATCAAGATAAATAATTGCTTCATTTTCTTGAGCAATACTGAAGCAGGATGA
AGTAAGAGGAATGCATTCATTTAAACATGCTTTGCTTTATGAATTTTGTCTCTTTTTTGGTCTCTTTTTCTTATATTCAAGTTACAAATG
TACAAGTATCCTTACTAAGAGTGCTCCTTTTGTATTTTACATATATACAGTATGAAAATACATTGGAACACTAGGAAAGTTTTTAAATAA
CAGTTCTAATTTATCAGAAAATTGTGTTTTGGGATTGAGTTCTTTGTCTCAGCCCAGAATCCCAGGTCCTGGGCCTGGTTTTCTAATGCT
GTCATCTCAGTTCGATATTTTACTTTAGAACCTGGAATCTCCTACTTAATATATGACCATGACTTTGAAAGGCAAAAGAGGAATCAAGAA
TAAATAAAACAAACTTAATCTTCATCTTTAAAAAAAAGAAAAAAGAAACCAAAATGAGAATCAACACTTCATAGGCTCACTGGGTTTTCT
TTTCTTTTCTGTTAATTTAAACTCAGTTATTTTTAATGCTTAATACATACATGGTGCAAAATTTAAAAAGCGCAAATAGGTATCTAGTGG
AAAACCTAAGCCTCCCTCTCTCCTCCGGCACCCATTACCTCTCCCTGGAGGCAACTGTTTTGATCCATTTCTTACACACACTGCCAGAGA
TACTCTAGGCATGTAAAGCACAAACATACATATAAAATCTGCGGGCTTCAAAAAATATAAGTAGGATGTCATCTATACTGTCATACACTT

>In-frame_ENST00000361905_ENST00000334956_TCGA-E7-A85H-01A_TEAD1_chr11_12785981_+_PARVA_chr11_12549396_length(amino acids)=176AA_start in transcript=528_stop in transcript=1
MGLVVTATQSFLDTMFLLTPENFPLECAMKRRRQRQQQSSAQGATAAPGESEANFGAASPALCSVPGSLPGSRSLGPATPPLPSTAPAPG

--------------------------------------------------------------
>In-frame_ENST00000527636_ENST00000334956_TCGA-E7-A85H-01A_TEAD1_chr11_12785981_+_PARVA_chr11_12549396_length(transcript)=3606nt_BP=653nt
GGCCGCGTCCAGGCACAGGCCATGCAGTGACGCCCCCCCACCCCTCCACCTTTGCCCGGAGCGCGGGCAGCAGCCCAGCGCGCCAGCCGG
CCCCGGGGCAGGAGCGGTGCTAGGCAGGGGTGGGGTGGCCGGGCCCAGGGACCGGGAGCCGGGGAGGGAGCCGGGCACCGAGCAGAGGGC
GGGGGAAGCGGCGCCGAAGTTTGCCTCGGACTCGCCGGGCGCTGCGGTGGCTCCCTGGGCCGAGGACTGTTGCTGCCGCTGCCGCCGCCG
CTTCATTGCACATTCAAGTGGAAAATTTTCAGGAGTCAGCAGAAACATTGTGTCCAAAAAAGACTGAGTCGCAGTTACCACCAAACCCAG
GAGGAGACTCTCCCTGGAAAACTTCCCTTCCCTTTCGGTTTATTTTCTTGAAAAGGCTCCAGGCTTCGGCTTGGAAAATCCCACCGCCAA
AATTGAGCCCAGCAGCTGGAGCGGCAGTGAGAGCCCTGCCGAAAACATGGAAAGGATGAGTGACTCTGCAGATAAGCCAATTGACAATGA
TGCAGAAGGGGTCTGGAGCCCCGACATCGAGCAAAGCTTTCAGGAGGCCCTGGCTATCTATCCACCATGTGGGAGGAGGAAAATCATCTT
ATCAGACGAAGGCAAAATGTATGACATAGTCAACTGTGACCTGAAATCTACACTACGAGTGTTGTACAACCTCTTCACCAAGTACCGTAA
CGTGGAGTGAGGGGCTGCCCTGGGCCCACCACTGCCCAAGAGTTCTTGCTGTTGGCGTACTGGACCCTCCTCCGAACTGCCTTACCCTGC
TTATTCCTGTCTCTTGCACTGTGCTCTCCCACAAGTCCAGCTGCAACCCAGAGATAGTGGAAACTGAAATTAGGAAGGAAATCATCAATA
ACTCAGTGGGCTGACCCATCCCTCCCAGGCGCTGGGGACCAACCTAGCAATGAAGGTTGGGAAGGTTGTTCCCTTCCCGGTGCCAGGTCC
AGATTTCCCTCCATGATTTGGGAACCAGCTTAGGCAAAAGAGTCCCCACAAGATGAAAATAAAGATCCTAGTTACCATTCAAAGGATGCT
AACTGTGTGTCAGGCCCCACACTAAGTGCTCTGCTCTGATATACTCAAGGCCATTAATCTTCAGGACTCCCATTGACGTAGGTGTTTCAT
TCCCCTTTTACAGATGAGGAAACTAAGGCTTGGAGGTTAAATGACTTGCCAGAAGTTGGAATTTTTTTCCTCTTTGAACATAACCTCTCC
CTTCTCCCTAAAGGTAACCACTATTCTGAGTCCAATCATCAAGGTTTTGCTTTTCTTTTTAGCTAAGTATGCATTCCTCAATAGTAGACA
GTACAACATGTTTATAACAAGCCAATTACATTATGTTCTTTGCATGTTCTAAAGTTGTGTATGTGTGTGCACATCTGAGCACGTGCACAT
GTACACCTGAGCCAAAAACACGAGAACCCACTGATCTCACCACTGGGGCAAGCTAGGTCAGAGCTTAGTGATTCACACTGAAATTGGCAA
ATTGGATTTAACCCAATTAATAGTGTGTGTGTGGCAGGAGTCATGTCCCTCACATCCTTTGTACAAATGAAAATTACTCTTAATTCCTTC
AGATTTATAATAACTCTGTACTTTGGTTTCAGGGTGACATTTGGGAAGGATTTTGTTTAGAATTAATGGAGTGGCACATTTTGCAGCCTT
TTTGCTTGATTGCATGTAATGGAAATGCCCTATATTTTCCTGCAAAATAAGTACTAAATTCATTATCGTTAAGCAAATGTACAATATGCT
CAGGCACCGCAGAGAGCTGGGCACGGGCCCATGTGAGCATCACTTTGGAAGTAGGGCTCTTCAACAGGGACCCTTGAACTTTAAAGAAAG
GAACTTCTTTTTGCCTTCTAATTGATCATTTAGACTATTCTGGCTAAGTCTGCCCACATGTAATTACCGGCTAATTCAAGCGAGGAAAAA
TGTAAGTCATTTAGACCAAAGCCAAGCAGTTTCTTTGCGTGGGTTACTCAAGGGCTTGTGGTTACTTGTATCTCCTCTATGTGAACTTGA
CTTTGAAAGACAGAGCTCTAGTGTGCCAGCCTGCTAAGTCCTGTAAGAATAGGGAAGGGCGGAGGGGGGTGGGCAGTGACTAGGGGACGA
GAAGCATGGGGAAAATATTTGCACTCTAAACATACAGAGATAGAGGTGGGGCTTGTGGTACTTAACACTTGTAGCCATCAACTGACTGAG
ACCTTGGGCTAAATAATCAATTGTGCTGATATTACATCTCGTTATGGAATGTTCCTAAATATGCCAGGTAGACACCAGCCCAAGTACCCT
CCTCCAGAAGTCTGTGACTACCTTGTCACTACTTTAGGCCCATTCCACAAAGCCCATCTCTGGTTTGAGAATTCATTTTGATCTGTATCT
ACACCACCCAAAGTTAGGCCTCCTATAATGTCCAAAACATTCCTTTCAGCCTTTTTATTTCTTACTGTACTGTCTCTTACTGTACTGTCT
ATCTGCAGTAATTGAGGACCCATAAAATTTAGATAACTACATGTCTTTGCTCTTAGAATTGTCACTCAGCATAATGAGCATTTAACATAC
AAAGGCAATGTACTGTTTTGTGTTGATCTATGTAAAAGAATACAATTCTTTTTTACATAATTAGTGAAATTTTATTTTTTATTAGGAAAC
ACTAAATAGTGTAATATTTCTTTTGCTTTTAAAAAAATTCCTGGTAGCAAATCAAGATAAATAATTGCTTCATTTTCTTGAGCAATACTG
AAGCAGGATGAAGTAAGAGGAATGCATTCATTTAAACATGCTTTGCTTTATGAATTTTGTCTCTTTTTTGGTCTCTTTTTCTTATATTCA
AGTTACAAATGTACAAGTATCCTTACTAAGAGTGCTCCTTTTGTATTTTACATATATACAGTATGAAAATACATTGGAACACTAGGAAAG
TTTTTAAATAACAGTTCTAATTTATCAGAAAATTGTGTTTTGGGATTGAGTTCTTTGTCTCAGCCCAGAATCCCAGGTCCTGGGCCTGGT
TTTCTAATGCTGTCATCTCAGTTCGATATTTTACTTTAGAACCTGGAATCTCCTACTTAATATATGACCATGACTTTGAAAGGCAAAAGA
GGAATCAAGAATAAATAAAACAAACTTAATCTTCATCTTTAAAAAAAAGAAAAAAGAAACCAAAATGAGAATCAACACTTCATAGGCTCA
CTGGGTTTTCTTTTCTTTTCTGTTAATTTAAACTCAGTTATTTTTAATGCTTAATACATACATGGTGCAAAATTTAAAAAGCGCAAATAG
GTATCTAGTGGAAAACCTAAGCCTCCCTCTCTCCTCCGGCACCCATTACCTCTCCCTGGAGGCAACTGTTTTGATCCATTTCTTACACAC
ACTGCCAGAGATACTCTAGGCATGTAAAGCACAAACATACATATAAAATCTGCGGGCTTCAAAAAATATAAGTAGGATGTCATCTATACT
GTCATACACTTTGTTTTTTATCACTTAATGTTATATCTTGGATATTGTATTACCCTGGGTATTAAAAAGAACTCCTTTCACATTTTAAAA

>In-frame_ENST00000527636_ENST00000334956_TCGA-E7-A85H-01A_TEAD1_chr11_12785981_+_PARVA_chr11_12549396_length(amino acids)=120AA_start in transcript=359_stop in transcript=0
MGLVVTATQSFLDTMFLLTPENFPLECAMKRRRQRQQQSSAQGATAAPGESEANFGAASPALCSVPGSLPGSRSLGPATPPLPSTAPAPG

--------------------------------------------------------------
>In-frame_ENST00000527575_ENST00000334956_TCGA-E7-A85H-01A_TEAD1_chr11_12785981_+_PARVA_chr11_12549396_length(transcript)=3268nt_BP=315nt
TCGCAGTTACCACCAAACCCAGGAGGAGACTCTCCCTGGAAAACTTCCCTTCCCTTTCGGTTTATTTTCTTGAAAAGGCTCCAGGCTTCG
GCTTGGAAAATCCCACCGCCAAAATTGAGCCCAGCAGCTGGAGCGGCAGTGAGAGCCCTGCCGAAAACATGGAAAGGATGAGTGACTCTG
CAGATAAGCCAATTGACAATGATGCAGAAGGGGTCTGGAGCCCCGACATCGAGCAAAGCTTTCAGGAGGCCCTGGCTATCTATCCACCAT
GTGGGAGGAGGAAAATCATCTTATCAGACGAAGGCAAAATGTATGACATAGTCAACTGTGACCTGAAATCTACACTACGAGTGTTGTACA
ACCTCTTCACCAAGTACCGTAACGTGGAGTGAGGGGCTGCCCTGGGCCCACCACTGCCCAAGAGTTCTTGCTGTTGGCGTACTGGACCCT
CCTCCGAACTGCCTTACCCTGCTTATTCCTGTCTCTTGCACTGTGCTCTCCCACAAGTCCAGCTGCAACCCAGAGATAGTGGAAACTGAA
ATTAGGAAGGAAATCATCAATAACTCAGTGGGCTGACCCATCCCTCCCAGGCGCTGGGGACCAACCTAGCAATGAAGGTTGGGAAGGTTG
TTCCCTTCCCGGTGCCAGGTCCAGATTTCCCTCCATGATTTGGGAACCAGCTTAGGCAAAAGAGTCCCCACAAGATGAAAATAAAGATCC
TAGTTACCATTCAAAGGATGCTAACTGTGTGTCAGGCCCCACACTAAGTGCTCTGCTCTGATATACTCAAGGCCATTAATCTTCAGGACT
CCCATTGACGTAGGTGTTTCATTCCCCTTTTACAGATGAGGAAACTAAGGCTTGGAGGTTAAATGACTTGCCAGAAGTTGGAATTTTTTT
CCTCTTTGAACATAACCTCTCCCTTCTCCCTAAAGGTAACCACTATTCTGAGTCCAATCATCAAGGTTTTGCTTTTCTTTTTAGCTAAGT
ATGCATTCCTCAATAGTAGACAGTACAACATGTTTATAACAAGCCAATTACATTATGTTCTTTGCATGTTCTAAAGTTGTGTATGTGTGT
GCACATCTGAGCACGTGCACATGTACACCTGAGCCAAAAACACGAGAACCCACTGATCTCACCACTGGGGCAAGCTAGGTCAGAGCTTAG
TGATTCACACTGAAATTGGCAAATTGGATTTAACCCAATTAATAGTGTGTGTGTGGCAGGAGTCATGTCCCTCACATCCTTTGTACAAAT
GAAAATTACTCTTAATTCCTTCAGATTTATAATAACTCTGTACTTTGGTTTCAGGGTGACATTTGGGAAGGATTTTGTTTAGAATTAATG
GAGTGGCACATTTTGCAGCCTTTTTGCTTGATTGCATGTAATGGAAATGCCCTATATTTTCCTGCAAAATAAGTACTAAATTCATTATCG
TTAAGCAAATGTACAATATGCTCAGGCACCGCAGAGAGCTGGGCACGGGCCCATGTGAGCATCACTTTGGAAGTAGGGCTCTTCAACAGG
GACCCTTGAACTTTAAAGAAAGGAACTTCTTTTTGCCTTCTAATTGATCATTTAGACTATTCTGGCTAAGTCTGCCCACATGTAATTACC
GGCTAATTCAAGCGAGGAAAAATGTAAGTCATTTAGACCAAAGCCAAGCAGTTTCTTTGCGTGGGTTACTCAAGGGCTTGTGGTTACTTG
TATCTCCTCTATGTGAACTTGACTTTGAAAGACAGAGCTCTAGTGTGCCAGCCTGCTAAGTCCTGTAAGAATAGGGAAGGGCGGAGGGGG
GTGGGCAGTGACTAGGGGACGAGAAGCATGGGGAAAATATTTGCACTCTAAACATACAGAGATAGAGGTGGGGCTTGTGGTACTTAACAC
TTGTAGCCATCAACTGACTGAGACCTTGGGCTAAATAATCAATTGTGCTGATATTACATCTCGTTATGGAATGTTCCTAAATATGCCAGG
TAGACACCAGCCCAAGTACCCTCCTCCAGAAGTCTGTGACTACCTTGTCACTACTTTAGGCCCATTCCACAAAGCCCATCTCTGGTTTGA
GAATTCATTTTGATCTGTATCTACACCACCCAAAGTTAGGCCTCCTATAATGTCCAAAACATTCCTTTCAGCCTTTTTATTTCTTACTGT
ACTGTCTCTTACTGTACTGTCTATCTGCAGTAATTGAGGACCCATAAAATTTAGATAACTACATGTCTTTGCTCTTAGAATTGTCACTCA
GCATAATGAGCATTTAACATACAAAGGCAATGTACTGTTTTGTGTTGATCTATGTAAAAGAATACAATTCTTTTTTACATAATTAGTGAA
ATTTTATTTTTTATTAGGAAACACTAAATAGTGTAATATTTCTTTTGCTTTTAAAAAAATTCCTGGTAGCAAATCAAGATAAATAATTGC
TTCATTTTCTTGAGCAATACTGAAGCAGGATGAAGTAAGAGGAATGCATTCATTTAAACATGCTTTGCTTTATGAATTTTGTCTCTTTTT
TGGTCTCTTTTTCTTATATTCAAGTTACAAATGTACAAGTATCCTTACTAAGAGTGCTCCTTTTGTATTTTACATATATACAGTATGAAA
ATACATTGGAACACTAGGAAAGTTTTTAAATAACAGTTCTAATTTATCAGAAAATTGTGTTTTGGGATTGAGTTCTTTGTCTCAGCCCAG
AATCCCAGGTCCTGGGCCTGGTTTTCTAATGCTGTCATCTCAGTTCGATATTTTACTTTAGAACCTGGAATCTCCTACTTAATATATGAC
CATGACTTTGAAAGGCAAAAGAGGAATCAAGAATAAATAAAACAAACTTAATCTTCATCTTTAAAAAAAAGAAAAAAGAAACCAAAATGA
GAATCAACACTTCATAGGCTCACTGGGTTTTCTTTTCTTTTCTGTTAATTTAAACTCAGTTATTTTTAATGCTTAATACATACATGGTGC
AAAATTTAAAAAGCGCAAATAGGTATCTAGTGGAAAACCTAAGCCTCCCTCTCTCCTCCGGCACCCATTACCTCTCCCTGGAGGCAACTG
TTTTGATCCATTTCTTACACACACTGCCAGAGATACTCTAGGCATGTAAAGCACAAACATACATATAAAATCTGCGGGCTTCAAAAAATA
TAAGTAGGATGTCATCTATACTGTCATACACTTTGTTTTTTATCACTTAATGTTATATCTTGGATATTGTATTACCCTGGGTATTAAAAA

>In-frame_ENST00000527575_ENST00000334956_TCGA-E7-A85H-01A_TEAD1_chr11_12785981_+_PARVA_chr11_12549396_length(amino acids)=118AA_start in transcript=35_stop in transcript=391
MENFPSLSVYFLEKAPGFGLENPTAKIEPSSWSGSESPAENMERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEG

--------------------------------------------------------------
>In-frame_ENST00000334310_ENST00000334956_TCGA-E7-A85H-01A_TEAD1_chr11_12785981_+_PARVA_chr11_12549396_length(transcript)=3268nt_BP=315nt
TCGCAGTTACCACCAAACCCAGGAGGAGACTCTCCCTGGAAAACTTCCCTTCCCTTTCGGTTTATTTTCTTGAAAAGGCTCCAGGCTTCG
GCTTGGAAAATCCCACCGCCAAAATTGAGCCCAGCAGCTGGAGCGGCAGTGAGAGCCCTGCCGAAAACATGGAAAGGATGAGTGACTCTG
CAGATAAGCCAATTGACAATGATGCAGAAGGGGTCTGGAGCCCCGACATCGAGCAAAGCTTTCAGGAGGCCCTGGCTATCTATCCACCAT
GTGGGAGGAGGAAAATCATCTTATCAGACGAAGGCAAAATGTATGACATAGTCAACTGTGACCTGAAATCTACACTACGAGTGTTGTACA
ACCTCTTCACCAAGTACCGTAACGTGGAGTGAGGGGCTGCCCTGGGCCCACCACTGCCCAAGAGTTCTTGCTGTTGGCGTACTGGACCCT
CCTCCGAACTGCCTTACCCTGCTTATTCCTGTCTCTTGCACTGTGCTCTCCCACAAGTCCAGCTGCAACCCAGAGATAGTGGAAACTGAA
ATTAGGAAGGAAATCATCAATAACTCAGTGGGCTGACCCATCCCTCCCAGGCGCTGGGGACCAACCTAGCAATGAAGGTTGGGAAGGTTG
TTCCCTTCCCGGTGCCAGGTCCAGATTTCCCTCCATGATTTGGGAACCAGCTTAGGCAAAAGAGTCCCCACAAGATGAAAATAAAGATCC
TAGTTACCATTCAAAGGATGCTAACTGTGTGTCAGGCCCCACACTAAGTGCTCTGCTCTGATATACTCAAGGCCATTAATCTTCAGGACT
CCCATTGACGTAGGTGTTTCATTCCCCTTTTACAGATGAGGAAACTAAGGCTTGGAGGTTAAATGACTTGCCAGAAGTTGGAATTTTTTT
CCTCTTTGAACATAACCTCTCCCTTCTCCCTAAAGGTAACCACTATTCTGAGTCCAATCATCAAGGTTTTGCTTTTCTTTTTAGCTAAGT
ATGCATTCCTCAATAGTAGACAGTACAACATGTTTATAACAAGCCAATTACATTATGTTCTTTGCATGTTCTAAAGTTGTGTATGTGTGT
GCACATCTGAGCACGTGCACATGTACACCTGAGCCAAAAACACGAGAACCCACTGATCTCACCACTGGGGCAAGCTAGGTCAGAGCTTAG
TGATTCACACTGAAATTGGCAAATTGGATTTAACCCAATTAATAGTGTGTGTGTGGCAGGAGTCATGTCCCTCACATCCTTTGTACAAAT
GAAAATTACTCTTAATTCCTTCAGATTTATAATAACTCTGTACTTTGGTTTCAGGGTGACATTTGGGAAGGATTTTGTTTAGAATTAATG
GAGTGGCACATTTTGCAGCCTTTTTGCTTGATTGCATGTAATGGAAATGCCCTATATTTTCCTGCAAAATAAGTACTAAATTCATTATCG
TTAAGCAAATGTACAATATGCTCAGGCACCGCAGAGAGCTGGGCACGGGCCCATGTGAGCATCACTTTGGAAGTAGGGCTCTTCAACAGG
GACCCTTGAACTTTAAAGAAAGGAACTTCTTTTTGCCTTCTAATTGATCATTTAGACTATTCTGGCTAAGTCTGCCCACATGTAATTACC
GGCTAATTCAAGCGAGGAAAAATGTAAGTCATTTAGACCAAAGCCAAGCAGTTTCTTTGCGTGGGTTACTCAAGGGCTTGTGGTTACTTG
TATCTCCTCTATGTGAACTTGACTTTGAAAGACAGAGCTCTAGTGTGCCAGCCTGCTAAGTCCTGTAAGAATAGGGAAGGGCGGAGGGGG
GTGGGCAGTGACTAGGGGACGAGAAGCATGGGGAAAATATTTGCACTCTAAACATACAGAGATAGAGGTGGGGCTTGTGGTACTTAACAC
TTGTAGCCATCAACTGACTGAGACCTTGGGCTAAATAATCAATTGTGCTGATATTACATCTCGTTATGGAATGTTCCTAAATATGCCAGG
TAGACACCAGCCCAAGTACCCTCCTCCAGAAGTCTGTGACTACCTTGTCACTACTTTAGGCCCATTCCACAAAGCCCATCTCTGGTTTGA
GAATTCATTTTGATCTGTATCTACACCACCCAAAGTTAGGCCTCCTATAATGTCCAAAACATTCCTTTCAGCCTTTTTATTTCTTACTGT
ACTGTCTCTTACTGTACTGTCTATCTGCAGTAATTGAGGACCCATAAAATTTAGATAACTACATGTCTTTGCTCTTAGAATTGTCACTCA
GCATAATGAGCATTTAACATACAAAGGCAATGTACTGTTTTGTGTTGATCTATGTAAAAGAATACAATTCTTTTTTACATAATTAGTGAA
ATTTTATTTTTTATTAGGAAACACTAAATAGTGTAATATTTCTTTTGCTTTTAAAAAAATTCCTGGTAGCAAATCAAGATAAATAATTGC
TTCATTTTCTTGAGCAATACTGAAGCAGGATGAAGTAAGAGGAATGCATTCATTTAAACATGCTTTGCTTTATGAATTTTGTCTCTTTTT
TGGTCTCTTTTTCTTATATTCAAGTTACAAATGTACAAGTATCCTTACTAAGAGTGCTCCTTTTGTATTTTACATATATACAGTATGAAA
ATACATTGGAACACTAGGAAAGTTTTTAAATAACAGTTCTAATTTATCAGAAAATTGTGTTTTGGGATTGAGTTCTTTGTCTCAGCCCAG
AATCCCAGGTCCTGGGCCTGGTTTTCTAATGCTGTCATCTCAGTTCGATATTTTACTTTAGAACCTGGAATCTCCTACTTAATATATGAC
CATGACTTTGAAAGGCAAAAGAGGAATCAAGAATAAATAAAACAAACTTAATCTTCATCTTTAAAAAAAAGAAAAAAGAAACCAAAATGA
GAATCAACACTTCATAGGCTCACTGGGTTTTCTTTTCTTTTCTGTTAATTTAAACTCAGTTATTTTTAATGCTTAATACATACATGGTGC
AAAATTTAAAAAGCGCAAATAGGTATCTAGTGGAAAACCTAAGCCTCCCTCTCTCCTCCGGCACCCATTACCTCTCCCTGGAGGCAACTG
TTTTGATCCATTTCTTACACACACTGCCAGAGATACTCTAGGCATGTAAAGCACAAACATACATATAAAATCTGCGGGCTTCAAAAAATA
TAAGTAGGATGTCATCTATACTGTCATACACTTTGTTTTTTATCACTTAATGTTATATCTTGGATATTGTATTACCCTGGGTATTAAAAA

>In-frame_ENST00000334310_ENST00000334956_TCGA-E7-A85H-01A_TEAD1_chr11_12785981_+_PARVA_chr11_12549396_length(amino acids)=118AA_start in transcript=35_stop in transcript=391
MENFPSLSVYFLEKAPGFGLENPTAKIEPSSWSGSESPAENMERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEG

--------------------------------------------------------------
>In-frame_ENST00000361985_ENST00000334956_TCGA-E7-A85H-01A_TEAD1_chr11_12785981_+_PARVA_chr11_12549396_length(transcript)=3309nt_BP=356nt
AGGGAGTGTGGTGGCATTGCTCTGCAGAGACATGAACAGCTCCCTGGGAGACACTGCTGGGGAAAGATGAGTCGAGTCTACGGTTTTTTC
TCATCCTCCTGTTTATTTTCTTGAAAAGGCTCCAGGCTTCGGCTTGGAAAATCCCACCGCCAAAATTGAGCCCAGCAGCTGGAGCGGCAG
TGAGAGCCCTGCCGAAAACATGGAAAGGATGAGTGACTCTGCAGATAAGCCAATTGACAATGATGCAGAAGGGGTCTGGAGCCCCGACAT
CGAGCAAAGCTTTCAGGAGGCCCTGGCTATCTATCCACCATGTGGGAGGAGGAAAATCATCTTATCAGACGAAGGCAAAATGTATGACAT
AGTCAACTGTGACCTGAAATCTACACTACGAGTGTTGTACAACCTCTTCACCAAGTACCGTAACGTGGAGTGAGGGGCTGCCCTGGGCCC
ACCACTGCCCAAGAGTTCTTGCTGTTGGCGTACTGGACCCTCCTCCGAACTGCCTTACCCTGCTTATTCCTGTCTCTTGCACTGTGCTCT
CCCACAAGTCCAGCTGCAACCCAGAGATAGTGGAAACTGAAATTAGGAAGGAAATCATCAATAACTCAGTGGGCTGACCCATCCCTCCCA
GGCGCTGGGGACCAACCTAGCAATGAAGGTTGGGAAGGTTGTTCCCTTCCCGGTGCCAGGTCCAGATTTCCCTCCATGATTTGGGAACCA
GCTTAGGCAAAAGAGTCCCCACAAGATGAAAATAAAGATCCTAGTTACCATTCAAAGGATGCTAACTGTGTGTCAGGCCCCACACTAAGT
GCTCTGCTCTGATATACTCAAGGCCATTAATCTTCAGGACTCCCATTGACGTAGGTGTTTCATTCCCCTTTTACAGATGAGGAAACTAAG
GCTTGGAGGTTAAATGACTTGCCAGAAGTTGGAATTTTTTTCCTCTTTGAACATAACCTCTCCCTTCTCCCTAAAGGTAACCACTATTCT
GAGTCCAATCATCAAGGTTTTGCTTTTCTTTTTAGCTAAGTATGCATTCCTCAATAGTAGACAGTACAACATGTTTATAACAAGCCAATT
ACATTATGTTCTTTGCATGTTCTAAAGTTGTGTATGTGTGTGCACATCTGAGCACGTGCACATGTACACCTGAGCCAAAAACACGAGAAC
CCACTGATCTCACCACTGGGGCAAGCTAGGTCAGAGCTTAGTGATTCACACTGAAATTGGCAAATTGGATTTAACCCAATTAATAGTGTG
TGTGTGGCAGGAGTCATGTCCCTCACATCCTTTGTACAAATGAAAATTACTCTTAATTCCTTCAGATTTATAATAACTCTGTACTTTGGT
TTCAGGGTGACATTTGGGAAGGATTTTGTTTAGAATTAATGGAGTGGCACATTTTGCAGCCTTTTTGCTTGATTGCATGTAATGGAAATG
CCCTATATTTTCCTGCAAAATAAGTACTAAATTCATTATCGTTAAGCAAATGTACAATATGCTCAGGCACCGCAGAGAGCTGGGCACGGG
CCCATGTGAGCATCACTTTGGAAGTAGGGCTCTTCAACAGGGACCCTTGAACTTTAAAGAAAGGAACTTCTTTTTGCCTTCTAATTGATC
ATTTAGACTATTCTGGCTAAGTCTGCCCACATGTAATTACCGGCTAATTCAAGCGAGGAAAAATGTAAGTCATTTAGACCAAAGCCAAGC
AGTTTCTTTGCGTGGGTTACTCAAGGGCTTGTGGTTACTTGTATCTCCTCTATGTGAACTTGACTTTGAAAGACAGAGCTCTAGTGTGCC
AGCCTGCTAAGTCCTGTAAGAATAGGGAAGGGCGGAGGGGGGTGGGCAGTGACTAGGGGACGAGAAGCATGGGGAAAATATTTGCACTCT
AAACATACAGAGATAGAGGTGGGGCTTGTGGTACTTAACACTTGTAGCCATCAACTGACTGAGACCTTGGGCTAAATAATCAATTGTGCT
GATATTACATCTCGTTATGGAATGTTCCTAAATATGCCAGGTAGACACCAGCCCAAGTACCCTCCTCCAGAAGTCTGTGACTACCTTGTC
ACTACTTTAGGCCCATTCCACAAAGCCCATCTCTGGTTTGAGAATTCATTTTGATCTGTATCTACACCACCCAAAGTTAGGCCTCCTATA
ATGTCCAAAACATTCCTTTCAGCCTTTTTATTTCTTACTGTACTGTCTCTTACTGTACTGTCTATCTGCAGTAATTGAGGACCCATAAAA
TTTAGATAACTACATGTCTTTGCTCTTAGAATTGTCACTCAGCATAATGAGCATTTAACATACAAAGGCAATGTACTGTTTTGTGTTGAT
CTATGTAAAAGAATACAATTCTTTTTTACATAATTAGTGAAATTTTATTTTTTATTAGGAAACACTAAATAGTGTAATATTTCTTTTGCT
TTTAAAAAAATTCCTGGTAGCAAATCAAGATAAATAATTGCTTCATTTTCTTGAGCAATACTGAAGCAGGATGAAGTAAGAGGAATGCAT
TCATTTAAACATGCTTTGCTTTATGAATTTTGTCTCTTTTTTGGTCTCTTTTTCTTATATTCAAGTTACAAATGTACAAGTATCCTTACT
AAGAGTGCTCCTTTTGTATTTTACATATATACAGTATGAAAATACATTGGAACACTAGGAAAGTTTTTAAATAACAGTTCTAATTTATCA
GAAAATTGTGTTTTGGGATTGAGTTCTTTGTCTCAGCCCAGAATCCCAGGTCCTGGGCCTGGTTTTCTAATGCTGTCATCTCAGTTCGAT
ATTTTACTTTAGAACCTGGAATCTCCTACTTAATATATGACCATGACTTTGAAAGGCAAAAGAGGAATCAAGAATAAATAAAACAAACTT
AATCTTCATCTTTAAAAAAAAGAAAAAAGAAACCAAAATGAGAATCAACACTTCATAGGCTCACTGGGTTTTCTTTTCTTTTCTGTTAAT
TTAAACTCAGTTATTTTTAATGCTTAATACATACATGGTGCAAAATTTAAAAAGCGCAAATAGGTATCTAGTGGAAAACCTAAGCCTCCC
TCTCTCCTCCGGCACCCATTACCTCTCCCTGGAGGCAACTGTTTTGATCCATTTCTTACACACACTGCCAGAGATACTCTAGGCATGTAA
AGCACAAACATACATATAAAATCTGCGGGCTTCAAAAAATATAAGTAGGATGTCATCTATACTGTCATACACTTTGTTTTTTATCACTTA

>In-frame_ENST00000361985_ENST00000334956_TCGA-E7-A85H-01A_TEAD1_chr11_12785981_+_PARVA_chr11_12549396_length(amino acids)=99AA_start in transcript=133_stop in transcript=432
MENPTAKIEPSSWSGSESPAENMERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYDIVNCDLKSTLRVLYN

--------------------------------------------------------------

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Fusion Gene PPI Analysis for TEAD1-PARVA


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgenePARVAchr11:12785981chr11:12549396ENST00000550549111321_25347.3333333333333373.0ARHGAP31


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TEAD1-PARVA


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TEAD1-PARVA


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneTEAD1C1862382SVEINSSON CHORIORETINAL ATROPHY3CTD_human;ORPHANET;UNIPROT
TgenePARVAC0013146Drug abuse1CTD_human
TgenePARVAC0013170Drug habituation1CTD_human
TgenePARVAC0013222Drug Use Disorders1CTD_human
TgenePARVAC0029231Organic Mental Disorders, Substance-Induced1CTD_human
TgenePARVAC0038580Substance Dependence1CTD_human
TgenePARVAC0038586Substance Use Disorders1CTD_human
TgenePARVAC0236969Substance-Related Disorders1CTD_human
TgenePARVAC0740858Substance abuse problem1CTD_human
TgenePARVAC1510472Drug Dependence1CTD_human
TgenePARVAC4316881Prescription Drug Abuse1CTD_human