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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TFG-CD46 (FusionGDB2 ID:89740)

Fusion Gene Summary for TFG-CD46

check button Fusion gene summary
Fusion gene informationFusion gene name: TFG-CD46
Fusion gene ID: 89740
HgeneTgene
Gene symbol

TFG

CD46

Gene ID

10342

4179

Gene nametrafficking from ER to golgi regulatorCD46 molecule
SynonymsHMSNP|SPG57|TF6|TRKT3AHUS2|MCP|MIC10|TLX|TRA2.10
Cytomap

3q12.2

1q32.2

Type of geneprotein-codingprotein-coding
Descriptionprotein TFGTRK-fusedTRK-fused gene proteinTRKT3 oncogenemembrane cofactor proteinCD46 antigen, complement regulatory proteinCD46 molecule, complement regulatory proteinantigen identified by monoclonal antibody TRA-2-10complement membrane cofactor proteinmeasles virus receptormembrane cofactor protein (CD
Modification date2020031320200313
UniProtAcc.

P15529

Ensembl transtripts involved in fusion geneENST00000418917, ENST00000490574, 
ENST00000240851, ENST00000476228, 
ENST00000481203, 		ENST00000367042, 
ENST00000354848, ENST00000441839, 
ENST00000322875, ENST00000367041, 
ENST00000358170, ENST00000322918, 
ENST00000361067, ENST00000367047, 
ENST00000357714, ENST00000469535, 
ENST00000360212, ENST00000480003, 
Fusion gene scores* DoF score13 X 14 X 7=127416 X 13 X 7=1456
# samples 1917
** MAII scorelog2(19/1274*10)=-2.74529395392535
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(17/1456*10)=-3.098403704061
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TFG [Title/Abstract] AND CD46 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTFG(100447702)-CD46(207941124), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneCD46

GO:0008593

regulation of Notch signaling pathway

23086448

TgeneCD46

GO:0010629

negative regulation of gene expression

23086448

TgeneCD46

GO:0032613

interleukin-10 production

23086448

TgeneCD46

GO:0032733

positive regulation of interleukin-10 production

12540904

TgeneCD46

GO:0035581

sequestering of extracellular ligand from receptor

23086448

TgeneCD46

GO:0042102

positive regulation of T cell proliferation

12540904

TgeneCD46

GO:0043382

positive regulation of memory T cell differentiation

12540904

TgeneCD46

GO:0045591

positive regulation of regulatory T cell differentiation

12540904

TgeneCD46

GO:0071636

positive regulation of transforming growth factor beta production

12540904


check buttonFusion gene breakpoints across TFG (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across CD46 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-66-2787-01ATFGchr3

100447702

+CD46chr1

207941124

+


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Fusion Gene ORF analysis for TFG-CD46

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000418917ENST00000367042TFGchr3

100447702

+CD46chr1

207941124

+
In-frameENST00000418917ENST00000354848TFGchr3

100447702

+CD46chr1

207941124

+
In-frameENST00000418917ENST00000441839TFGchr3

100447702

+CD46chr1

207941124

+
In-frameENST00000418917ENST00000322875TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000418917ENST00000367041TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000418917ENST00000358170TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000418917ENST00000322918TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000418917ENST00000361067TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000418917ENST00000367047TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000418917ENST00000357714TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-3UTRENST00000418917ENST00000469535TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000418917ENST00000360212TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000418917ENST00000480003TFGchr3

100447702

+CD46chr1

207941124

+
In-frameENST00000490574ENST00000367042TFGchr3

100447702

+CD46chr1

207941124

+
In-frameENST00000490574ENST00000354848TFGchr3

100447702

+CD46chr1

207941124

+
In-frameENST00000490574ENST00000441839TFGchr3

100447702

+CD46chr1

207941124

+
In-frameENST00000490574ENST00000322875TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000490574ENST00000367041TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000490574ENST00000358170TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000490574ENST00000322918TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000490574ENST00000361067TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000490574ENST00000367047TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000490574ENST00000357714TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-3UTRENST00000490574ENST00000469535TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000490574ENST00000360212TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000490574ENST00000480003TFGchr3

100447702

+CD46chr1

207941124

+
In-frameENST00000240851ENST00000367042TFGchr3

100447702

+CD46chr1

207941124

+
In-frameENST00000240851ENST00000354848TFGchr3

100447702

+CD46chr1

207941124

+
In-frameENST00000240851ENST00000441839TFGchr3

100447702

+CD46chr1

207941124

+
In-frameENST00000240851ENST00000322875TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000240851ENST00000367041TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000240851ENST00000358170TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000240851ENST00000322918TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000240851ENST00000361067TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000240851ENST00000367047TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000240851ENST00000357714TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-3UTRENST00000240851ENST00000469535TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000240851ENST00000360212TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000240851ENST00000480003TFGchr3

100447702

+CD46chr1

207941124

+
In-frameENST00000476228ENST00000367042TFGchr3

100447702

+CD46chr1

207941124

+
In-frameENST00000476228ENST00000354848TFGchr3

100447702

+CD46chr1

207941124

+
In-frameENST00000476228ENST00000441839TFGchr3

100447702

+CD46chr1

207941124

+
In-frameENST00000476228ENST00000322875TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000476228ENST00000367041TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000476228ENST00000358170TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000476228ENST00000322918TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000476228ENST00000361067TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000476228ENST00000367047TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000476228ENST00000357714TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-3UTRENST00000476228ENST00000469535TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000476228ENST00000360212TFGchr3

100447702

+CD46chr1

207941124

+
5CDS-intronENST00000476228ENST00000480003TFGchr3

100447702

+CD46chr1

207941124

+
intron-3CDSENST00000481203ENST00000367042TFGchr3

100447702

+CD46chr1

207941124

+
intron-3CDSENST00000481203ENST00000354848TFGchr3

100447702

+CD46chr1

207941124

+
intron-3CDSENST00000481203ENST00000441839TFGchr3

100447702

+CD46chr1

207941124

+
intron-3CDSENST00000481203ENST00000322875TFGchr3

100447702

+CD46chr1

207941124

+
intron-intronENST00000481203ENST00000367041TFGchr3

100447702

+CD46chr1

207941124

+
intron-intronENST00000481203ENST00000358170TFGchr3

100447702

+CD46chr1

207941124

+
intron-intronENST00000481203ENST00000322918TFGchr3

100447702

+CD46chr1

207941124

+
intron-intronENST00000481203ENST00000361067TFGchr3

100447702

+CD46chr1

207941124

+
intron-intronENST00000481203ENST00000367047TFGchr3

100447702

+CD46chr1

207941124

+
intron-intronENST00000481203ENST00000357714TFGchr3

100447702

+CD46chr1

207941124

+
intron-3UTRENST00000481203ENST00000469535TFGchr3

100447702

+CD46chr1

207941124

+
intron-intronENST00000481203ENST00000360212TFGchr3

100447702

+CD46chr1

207941124

+
intron-intronENST00000481203ENST00000480003TFGchr3

100447702

+CD46chr1

207941124

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000418917TFGchr3100447702+ENST00000367042CD46chr1207941124+2843529102806234
ENST00000418917TFGchr3100447702+ENST00000354848CD46chr1207941124+2750529102827241
ENST00000418917TFGchr3100447702+ENST00000441839CD46chr1207941124+2686529102767221
ENST00000418917TFGchr3100447702+ENST00000322875CD46chr1207941124+2750529102827241
ENST00000490574TFGchr3100447702+ENST00000367042CD46chr1207941124+282651285789234
ENST00000490574TFGchr3100447702+ENST00000354848CD46chr1207941124+273351285810241
ENST00000490574TFGchr3100447702+ENST00000441839CD46chr1207941124+266951285750221
ENST00000490574TFGchr3100447702+ENST00000322875CD46chr1207941124+273351285810241
ENST00000240851TFGchr3100447702+ENST00000367042CD46chr1207941124+30697553281032234
ENST00000240851TFGchr3100447702+ENST00000354848CD46chr1207941124+29767553281053241
ENST00000240851TFGchr3100447702+ENST00000441839CD46chr1207941124+2912755328993221
ENST00000240851TFGchr3100447702+ENST00000322875CD46chr1207941124+29767553281053241
ENST00000476228TFGchr3100447702+ENST00000367042CD46chr1207941124+2888574147851234
ENST00000476228TFGchr3100447702+ENST00000354848CD46chr1207941124+2795574147872241
ENST00000476228TFGchr3100447702+ENST00000441839CD46chr1207941124+2731574147812221
ENST00000476228TFGchr3100447702+ENST00000322875CD46chr1207941124+2795574147872241

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000418917ENST00000367042TFGchr3100447702+CD46chr1207941124+0.0004547630.99954516
ENST00000418917ENST00000354848TFGchr3100447702+CD46chr1207941124+0.0006219740.99937797
ENST00000418917ENST00000441839TFGchr3100447702+CD46chr1207941124+0.0008415170.9991585
ENST00000418917ENST00000322875TFGchr3100447702+CD46chr1207941124+0.0006219740.99937797
ENST00000490574ENST00000367042TFGchr3100447702+CD46chr1207941124+0.0005205310.9994795
ENST00000490574ENST00000354848TFGchr3100447702+CD46chr1207941124+0.0005899240.99941003
ENST00000490574ENST00000441839TFGchr3100447702+CD46chr1207941124+0.0009152380.9990847
ENST00000490574ENST00000322875TFGchr3100447702+CD46chr1207941124+0.0005899240.99941003
ENST00000240851ENST00000367042TFGchr3100447702+CD46chr1207941124+0.0005353210.9994647
ENST00000240851ENST00000354848TFGchr3100447702+CD46chr1207941124+0.0006061850.9993938
ENST00000240851ENST00000441839TFGchr3100447702+CD46chr1207941124+0.0005980750.9994019
ENST00000240851ENST00000322875TFGchr3100447702+CD46chr1207941124+0.0006061850.9993938
ENST00000476228ENST00000367042TFGchr3100447702+CD46chr1207941124+0.000529460.99947053
ENST00000476228ENST00000354848TFGchr3100447702+CD46chr1207941124+0.0006227690.9993773
ENST00000476228ENST00000441839TFGchr3100447702+CD46chr1207941124+0.0008122480.99918777
ENST00000476228ENST00000322875TFGchr3100447702+CD46chr1207941124+0.0006227690.9993773

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Fusion Genomic Features for TFG-CD46


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
TFGchr3100447702+CD46chr1207941123+4.04E-070.99999964
TFGchr3100447702+CD46chr1207941123+4.04E-070.99999964

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TFG-CD46


check button Go to

FGviewer for the breakpoints of chr3:100447702-chr1:207941124

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CD46

P15529

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. {ECO:0000269|PubMed:10843656, ECO:0000269|PubMed:12540904}.; FUNCTION: (Microbial infection) A number of viral and bacterial pathogens seem to bind MCP in order to exploit its immune regulation property and directly induce an immunosuppressive phenotype in T-cells.; FUNCTION: (Microbial infection) Acts as a receptor for Adenovirus subgroup B2 and Ad3. {ECO:0000269|PubMed:12915534, ECO:0000269|PubMed:14566335, ECO:0000269|PubMed:15047806, ECO:0000269|PubMed:15078926, ECO:0000269|PubMed:15919905, ECO:0000269|PubMed:16254377}.; FUNCTION: (Microbial infection) Acts as a receptor for cultured Measles virus. {ECO:0000269|PubMed:10972291}.; FUNCTION: (Microbial infection) Acts as a receptor for Herpesvirus 6/HHV-6. {ECO:0000269|PubMed:12663806, ECO:0000269|PubMed:12724329}.; FUNCTION: (Microbial infection) May act as a receptor for pathogenic bacteria Neisseria and Streptococcus pyogenes (PubMed:7708671, PubMed:9379894, PubMed:11260136, PubMed:11971006).

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTFGchr3:100447702chr1:207941124ENST00000240851+4897_124138.33333333333334401.0Coiled coilOntology_term=ECO:0000255
HgeneTFGchr3:100447702chr1:207941124ENST00000418917+4897_124138.33333333333334397.0Coiled coilOntology_term=ECO:0000255
HgeneTFGchr3:100447702chr1:207941124ENST00000476228+4897_124138.33333333333334397.0Coiled coilOntology_term=ECO:0000255
HgeneTFGchr3:100447702chr1:207941124ENST00000490574+4897_124138.33333333333334401.0Coiled coilOntology_term=ECO:0000255
HgeneTFGchr3:100447702chr1:207941124ENST00000240851+4810_91138.33333333333334401.0DomainPB1
HgeneTFGchr3:100447702chr1:207941124ENST00000418917+4810_91138.33333333333334397.0DomainPB1
HgeneTFGchr3:100447702chr1:207941124ENST00000476228+4810_91138.33333333333334397.0DomainPB1
HgeneTFGchr3:100447702chr1:207941124ENST00000490574+4810_91138.33333333333334401.0DomainPB1
TgeneCD46chr3:100447702chr1:207941124ENST00000322875613302_326300.3333333333333400.0Compositional biasNote=Ser/Thr-rich
TgeneCD46chr3:100447702chr1:207941124ENST00000322918010302_3260350.0Compositional biasNote=Ser/Thr-rich
TgeneCD46chr3:100447702chr1:207941124ENST00000354848512302_326285.3333333333333385.0Compositional biasNote=Ser/Thr-rich
TgeneCD46chr3:100447702chr1:207941124ENST00000357714011302_3260370.0Compositional biasNote=Ser/Thr-rich
TgeneCD46chr3:100447702chr1:207941124ENST00000358170614302_326300.3333333333333973.6666666666666Compositional biasNote=Ser/Thr-rich
TgeneCD46chr3:100447702chr1:207941124ENST00000360212010302_3260356.0Compositional biasNote=Ser/Thr-rich
TgeneCD46chr3:100447702chr1:207941124ENST00000361067612302_326300.3333333333333386.0Compositional biasNote=Ser/Thr-rich
TgeneCD46chr3:100447702chr1:207941124ENST00000367041012302_3260943.6666666666666Compositional biasNote=Ser/Thr-rich
TgeneCD46chr3:100447702chr1:207941124ENST00000367042513302_326285.3333333333333958.6666666666666Compositional biasNote=Ser/Thr-rich
TgeneCD46chr3:100447702chr1:207941124ENST00000367047512302_326237.33333333333334337.0Compositional biasNote=Ser/Thr-rich
TgeneCD46chr3:100447702chr1:207941124ENST00000441839511302_326285.3333333333333365.0Compositional biasNote=Ser/Thr-rich
TgeneCD46chr3:100447702chr1:207941124ENST00000480003511302_326285.3333333333333371.0Compositional biasNote=Ser/Thr-rich
TgeneCD46chr3:100447702chr1:207941124ENST00000322918010160_2250350.0DomainSushi 3
TgeneCD46chr3:100447702chr1:207941124ENST00000322918010226_2850350.0DomainSushi 4
TgeneCD46chr3:100447702chr1:207941124ENST0000032291801035_960350.0DomainSushi 1
TgeneCD46chr3:100447702chr1:207941124ENST0000032291801097_1590350.0DomainSushi 2
TgeneCD46chr3:100447702chr1:207941124ENST00000357714011160_2250370.0DomainSushi 3
TgeneCD46chr3:100447702chr1:207941124ENST00000357714011226_2850370.0DomainSushi 4
TgeneCD46chr3:100447702chr1:207941124ENST0000035771401135_960370.0DomainSushi 1
TgeneCD46chr3:100447702chr1:207941124ENST0000035771401197_1590370.0DomainSushi 2
TgeneCD46chr3:100447702chr1:207941124ENST00000360212010160_2250356.0DomainSushi 3
TgeneCD46chr3:100447702chr1:207941124ENST00000360212010226_2850356.0DomainSushi 4
TgeneCD46chr3:100447702chr1:207941124ENST0000036021201035_960356.0DomainSushi 1
TgeneCD46chr3:100447702chr1:207941124ENST0000036021201097_1590356.0DomainSushi 2
TgeneCD46chr3:100447702chr1:207941124ENST00000367041012160_2250943.6666666666666DomainSushi 3
TgeneCD46chr3:100447702chr1:207941124ENST00000367041012226_2850943.6666666666666DomainSushi 4
TgeneCD46chr3:100447702chr1:207941124ENST0000036704101235_960943.6666666666666DomainSushi 1
TgeneCD46chr3:100447702chr1:207941124ENST0000036704101297_1590943.6666666666666DomainSushi 2
TgeneCD46chr3:100447702chr1:207941124ENST00000322875613367_392300.3333333333333400.0Topological domainCytoplasmic
TgeneCD46chr3:100447702chr1:207941124ENST0000032291801035_3430350.0Topological domainExtracellular
TgeneCD46chr3:100447702chr1:207941124ENST00000322918010367_3920350.0Topological domainCytoplasmic
TgeneCD46chr3:100447702chr1:207941124ENST00000354848512367_392285.3333333333333385.0Topological domainCytoplasmic
TgeneCD46chr3:100447702chr1:207941124ENST0000035771401135_3430370.0Topological domainExtracellular
TgeneCD46chr3:100447702chr1:207941124ENST00000357714011367_3920370.0Topological domainCytoplasmic
TgeneCD46chr3:100447702chr1:207941124ENST00000358170614367_392300.3333333333333973.6666666666666Topological domainCytoplasmic
TgeneCD46chr3:100447702chr1:207941124ENST0000036021201035_3430356.0Topological domainExtracellular
TgeneCD46chr3:100447702chr1:207941124ENST00000360212010367_3920356.0Topological domainCytoplasmic
TgeneCD46chr3:100447702chr1:207941124ENST00000361067612367_392300.3333333333333386.0Topological domainCytoplasmic
TgeneCD46chr3:100447702chr1:207941124ENST0000036704101235_3430943.6666666666666Topological domainExtracellular
TgeneCD46chr3:100447702chr1:207941124ENST00000367041012367_3920943.6666666666666Topological domainCytoplasmic
TgeneCD46chr3:100447702chr1:207941124ENST00000367042513367_392285.3333333333333958.6666666666666Topological domainCytoplasmic
TgeneCD46chr3:100447702chr1:207941124ENST00000367047512367_392237.33333333333334337.0Topological domainCytoplasmic
TgeneCD46chr3:100447702chr1:207941124ENST00000441839511367_392285.3333333333333365.0Topological domainCytoplasmic
TgeneCD46chr3:100447702chr1:207941124ENST00000480003511367_392285.3333333333333371.0Topological domainCytoplasmic
TgeneCD46chr3:100447702chr1:207941124ENST00000322875613344_366300.3333333333333400.0TransmembraneHelical
TgeneCD46chr3:100447702chr1:207941124ENST00000322918010344_3660350.0TransmembraneHelical
TgeneCD46chr3:100447702chr1:207941124ENST00000354848512344_366285.3333333333333385.0TransmembraneHelical
TgeneCD46chr3:100447702chr1:207941124ENST00000357714011344_3660370.0TransmembraneHelical
TgeneCD46chr3:100447702chr1:207941124ENST00000358170614344_366300.3333333333333973.6666666666666TransmembraneHelical
TgeneCD46chr3:100447702chr1:207941124ENST00000360212010344_3660356.0TransmembraneHelical
TgeneCD46chr3:100447702chr1:207941124ENST00000361067612344_366300.3333333333333386.0TransmembraneHelical
TgeneCD46chr3:100447702chr1:207941124ENST00000367041012344_3660943.6666666666666TransmembraneHelical
TgeneCD46chr3:100447702chr1:207941124ENST00000367042513344_366285.3333333333333958.6666666666666TransmembraneHelical
TgeneCD46chr3:100447702chr1:207941124ENST00000367047512344_366237.33333333333334337.0TransmembraneHelical
TgeneCD46chr3:100447702chr1:207941124ENST00000441839511344_366285.3333333333333365.0TransmembraneHelical
TgeneCD46chr3:100447702chr1:207941124ENST00000480003511344_366285.3333333333333371.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCD46chr3:100447702chr1:207941124ENST00000322875613160_225300.3333333333333400.0DomainSushi 3
TgeneCD46chr3:100447702chr1:207941124ENST00000322875613226_285300.3333333333333400.0DomainSushi 4
TgeneCD46chr3:100447702chr1:207941124ENST0000032287561335_96300.3333333333333400.0DomainSushi 1
TgeneCD46chr3:100447702chr1:207941124ENST0000032287561397_159300.3333333333333400.0DomainSushi 2
TgeneCD46chr3:100447702chr1:207941124ENST00000354848512160_225285.3333333333333385.0DomainSushi 3
TgeneCD46chr3:100447702chr1:207941124ENST00000354848512226_285285.3333333333333385.0DomainSushi 4
TgeneCD46chr3:100447702chr1:207941124ENST0000035484851235_96285.3333333333333385.0DomainSushi 1
TgeneCD46chr3:100447702chr1:207941124ENST0000035484851297_159285.3333333333333385.0DomainSushi 2
TgeneCD46chr3:100447702chr1:207941124ENST00000358170614160_225300.3333333333333973.6666666666666DomainSushi 3
TgeneCD46chr3:100447702chr1:207941124ENST00000358170614226_285300.3333333333333973.6666666666666DomainSushi 4
TgeneCD46chr3:100447702chr1:207941124ENST0000035817061435_96300.3333333333333973.6666666666666DomainSushi 1
TgeneCD46chr3:100447702chr1:207941124ENST0000035817061497_159300.3333333333333973.6666666666666DomainSushi 2
TgeneCD46chr3:100447702chr1:207941124ENST00000361067612160_225300.3333333333333386.0DomainSushi 3
TgeneCD46chr3:100447702chr1:207941124ENST00000361067612226_285300.3333333333333386.0DomainSushi 4
TgeneCD46chr3:100447702chr1:207941124ENST0000036106761235_96300.3333333333333386.0DomainSushi 1
TgeneCD46chr3:100447702chr1:207941124ENST0000036106761297_159300.3333333333333386.0DomainSushi 2
TgeneCD46chr3:100447702chr1:207941124ENST00000367042513160_225285.3333333333333958.6666666666666DomainSushi 3
TgeneCD46chr3:100447702chr1:207941124ENST00000367042513226_285285.3333333333333958.6666666666666DomainSushi 4
TgeneCD46chr3:100447702chr1:207941124ENST0000036704251335_96285.3333333333333958.6666666666666DomainSushi 1
TgeneCD46chr3:100447702chr1:207941124ENST0000036704251397_159285.3333333333333958.6666666666666DomainSushi 2
TgeneCD46chr3:100447702chr1:207941124ENST00000367047512160_225237.33333333333334337.0DomainSushi 3
TgeneCD46chr3:100447702chr1:207941124ENST00000367047512226_285237.33333333333334337.0DomainSushi 4
TgeneCD46chr3:100447702chr1:207941124ENST0000036704751235_96237.33333333333334337.0DomainSushi 1
TgeneCD46chr3:100447702chr1:207941124ENST0000036704751297_159237.33333333333334337.0DomainSushi 2
TgeneCD46chr3:100447702chr1:207941124ENST00000441839511160_225285.3333333333333365.0DomainSushi 3
TgeneCD46chr3:100447702chr1:207941124ENST00000441839511226_285285.3333333333333365.0DomainSushi 4
TgeneCD46chr3:100447702chr1:207941124ENST0000044183951135_96285.3333333333333365.0DomainSushi 1
TgeneCD46chr3:100447702chr1:207941124ENST0000044183951197_159285.3333333333333365.0DomainSushi 2
TgeneCD46chr3:100447702chr1:207941124ENST00000480003511160_225285.3333333333333371.0DomainSushi 3
TgeneCD46chr3:100447702chr1:207941124ENST00000480003511226_285285.3333333333333371.0DomainSushi 4
TgeneCD46chr3:100447702chr1:207941124ENST0000048000351135_96285.3333333333333371.0DomainSushi 1
TgeneCD46chr3:100447702chr1:207941124ENST0000048000351197_159285.3333333333333371.0DomainSushi 2
TgeneCD46chr3:100447702chr1:207941124ENST0000032287561335_343300.3333333333333400.0Topological domainExtracellular
TgeneCD46chr3:100447702chr1:207941124ENST0000035484851235_343285.3333333333333385.0Topological domainExtracellular
TgeneCD46chr3:100447702chr1:207941124ENST0000035817061435_343300.3333333333333973.6666666666666Topological domainExtracellular
TgeneCD46chr3:100447702chr1:207941124ENST0000036106761235_343300.3333333333333386.0Topological domainExtracellular
TgeneCD46chr3:100447702chr1:207941124ENST0000036704251335_343285.3333333333333958.6666666666666Topological domainExtracellular
TgeneCD46chr3:100447702chr1:207941124ENST0000036704751235_343237.33333333333334337.0Topological domainExtracellular
TgeneCD46chr3:100447702chr1:207941124ENST0000044183951135_343285.3333333333333365.0Topological domainExtracellular
TgeneCD46chr3:100447702chr1:207941124ENST0000048000351135_343285.3333333333333371.0Topological domainExtracellular


Top

Fusion Gene Sequence for TFG-CD46


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000418917_ENST00000367042_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(transcript)=2843nt_BP=529nt
AGGGACTCTTCGGCCTAGGCAGCCGGGACCCAGCCAGCCCTGCGCCTCGCGCCGTCGCGCATGCGTCCTGGTCTTTCTCTAGAGTTGTAT
ATATAGAACATCCTGGAGTCCACCATGAACGGACAGTTGGATCTAAGTGGGAAGCTAATCATCAAAGCTCAACTTGGGGAGGATATTCGG
CGAATTCCTATTCATAATGAAGATATTACTTATGATGAATTAGTGCTAATGATGCAACGAGTTTTCAGAGGAAAACTTCTGAGTAATGAT
GAAGTAACAATAAAGTATAAAGATGAAGATGGAGATCTTATAACAATTTTTGATAGTTCTGACCTTTCCTTTGCAATTCAGTGCAGTAGG
ATACTGAAACTGACATTATTTGTTAATGGCCAGCCAAGACCCCTTGAATCAAGTCAGGTGAAATATCTCCGTCGAGAACTGATAGAACTT
CGAAATAAAGTGAATCGTTTATTGGATAGCTTGGAACCACCTGGAGAACCAGGACCTTCCACCAATATTCCTGAAAATGTGTCGACTTCT
TCCACTACAAAATCTCCAGCGTCCAGTGCCTCAGGTCCTAGGCCTACTTACAAGCCTCCAGTCTCAAATTATCCAGGATATCCTAAACCT
GAGGAAGGAATACTTGACAGTTTGGATGTTTGGGTCATTGCTGTGATTGTTATTGCCATAGTTGTTGGAGTTGCAGTAATTTGTGTTGTC
CCGTACAGATATCTTCAAAGGAGGAAGAAGAAAGGCACATACCTAACTGATGAGACCCACAGAGAAGTAAAATTTACTTCTCTCTGAGAA
GGAGAGATGAGAGAAAGGTTTGCTTTTATCATTAAAAGGAAAGCAGATGGTGGAGCTGAATATGCCACTTACCAGACTAAATCAACCACT
CCAGCAGAGCAGAGAGGCTGAATAGATTCCACAACCTGGTTTGCCAGTTCATCTTTTGACTCTATTAAAATCTTCAATAGTTGTTATTCT
GTAGTTTCACTCTCATGAGTGCAACTGTGGCTTAGCTAATATTGCAATGTGGCTTGAATGTAGGTAGCATCCTTTGATGCTTCTTTGAAA
CTTGTATGAATTTGGGTATGAACAGATTGCCTGCTTTCCCTTAAATAACACTTAGATTTATTGGACCAGTCAGCACAGCATGCCTGGTTG
TATTAAAGCAGGGATATGCTGTATTTTATAAAATTGGCAAAATTAGAGAAATATAGTTCACAATGAAATTATATTTTCTTTGTAAAGAAA
GTGGCTTGAAATCTTTTTTGTTCAAAGATTAATGCCAACTCTTAAGATTATTCTTTCACCAACTATAGAATGTATTTTATATATCGTTCA
TTGTAAAAAGCCCTTAAAAATATGTGTATACTACTTTGGCTCTTGTGCATAAAAACAAGAACACTGAAAATTGGGAATATGCACAAACTT
GGCTTCTTTAACCAAGAATATTATTGGAAAATTCTCTAAAAGTTAATAGGGTAAATTCTCTATTTTTTGTAATGTGTTCGGTGATTTCAG
AAAGCTAGAAAGTGTATGTGTGGCATTTGTTTTCACTTTTTAAAACATCCCTAACTGATCGAATATATCAGTAATTTCAGAATCAGATGC
ATCCTTTCATAAGAAGTGAGAGGACTCTGACAGCCATAACAGGAGTGCCACTTCATGGTGCGAAGTGAACACTGTAGTCTTGTTGTTTTC
CCAAAGAGAACTCCGTATGTTCTCTTAGGTTGAGTAACCCACTCTGAATTCTGGTTACATGTGTTTTTCTCTCCCTCCTTAAATAAAGAG
AGGGGTTAAACATGCCCTCTAAAAGTAGGTGGTTTTGAAGAGAATAAATTCATCAGATAACCTCAAGTCACATGAGAATCTTAGTCCATT
TACATTGCCTTGGCTAGTAAAAGCCATCTATGTATATGTCTTACCTCATCTCCTAAAAGGCAGAGTACAAAGTAAGCCATGTATCTCAGG
AAGGTAACTTCATTTTGTCTATTTGCTGTTGATTGTACCAAGGGATGGAAGAAGTAAATATAGCTCAGGTAGCACTTTATACTCAGGCAG
ATCTCAGCCCTCTACTGAGTCCCTTAGCCAAGCAGTTTCTTTCAAAGAAGCCAGCAGGCGAAAAGCAGGGACTGCCACTGCATTTCATAT
CACACTGTTAAAAGTTGTGTTTTGAAATTTTATGTTTAGTTGCACAAATTGGGCCAAAGAAACATTGCCTTGAGGAAGATATGATTGGAA
AATCAAGAGTGTAGAAGAATAAATACTGTTTTACTGTCCAAAGACATGTTTATAGTGCTCTGTAAATGTTCCTTTCCTTTGTAGTCTCTG
GCAAGATGCTTTAGGAAGATAAAAGTTTGAGGAGAACAAACAGGAATTCTGAATTAAGCACAGAGTTGAAGTTTATACCCGTTTCACATG
CTTTTCAAGAATGTCGCAATTACTAAGAAGCAGATAATGGTGTTTTTTAGAAACCTAATTGAAGTATATTCAACCAAATACTTTAATGTA
TAAAATAAATATTATACAATATACTTGTATAGCAGTTTCTGCTTCACATTTGATTTTTTCAAATTTAATATTTATATTAGAGATCTATAT
ATGTATAAATATGTATTTTGTCAAATTTGTTACTTAAATATATAGAGACCAGTTTTCTCTGGAAGTTTGTTTAAATGACAGAAGCGTATA
TGAATTCAAGAAAATTTAAGCTGCAAAAATGTATTTGCTATAAAATGAGAAGTCTCACTGATAGAGGTTCTTTATTGCTCATTTTTTAAA

>In-frame_ENST00000418917_ENST00000367042_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(amino acids)=234AA_start in transcript=102_stop in transcript=806
MESTMNGQLDLSGKLIIKAQLGEDIRRIPIHNEDITYDELVLMMQRVFRGKLLSNDEVTIKYKDEDGDLITIFDSSDLSFAIQCSRILKL
TLFVNGQPRPLESSQVKYLRRELIELRNKVNRLLDSLEPPGEPGPSTNIPENVSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGI

--------------------------------------------------------------
>In-frame_ENST00000418917_ENST00000354848_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(transcript)=2750nt_BP=529nt
AGGGACTCTTCGGCCTAGGCAGCCGGGACCCAGCCAGCCCTGCGCCTCGCGCCGTCGCGCATGCGTCCTGGTCTTTCTCTAGAGTTGTAT
ATATAGAACATCCTGGAGTCCACCATGAACGGACAGTTGGATCTAAGTGGGAAGCTAATCATCAAAGCTCAACTTGGGGAGGATATTCGG
CGAATTCCTATTCATAATGAAGATATTACTTATGATGAATTAGTGCTAATGATGCAACGAGTTTTCAGAGGAAAACTTCTGAGTAATGAT
GAAGTAACAATAAAGTATAAAGATGAAGATGGAGATCTTATAACAATTTTTGATAGTTCTGACCTTTCCTTTGCAATTCAGTGCAGTAGG
ATACTGAAACTGACATTATTTGTTAATGGCCAGCCAAGACCCCTTGAATCAAGTCAGGTGAAATATCTCCGTCGAGAACTGATAGAACTT
CGAAATAAAGTGAATCGTTTATTGGATAGCTTGGAACCACCTGGAGAACCAGGACCTTCCACCAATATTCCTGAAAATGTGTCGACTTCT
TCCACTACAAAATCTCCAGCGTCCAGTGCCTCAGGTCCTAGGCCTACTTACAAGCCTCCAGTCTCAAATTATCCAGGATATCCTAAACCT
GAGGAAGGAATACTTGACAGTTTGGATGTTTGGGTCATTGCTGTGATTGTTATTGCCATAGTTGTTGGAGTTGCAGTAATTTGTGTTGTC
CCGTACAGATATCTTCAAAGGAGGAAGAAGAAAGGGAAAGCAGATGGTGGAGCTGAATATGCCACTTACCAGACTAAATCAACCACTCCA
GCAGAGCAGAGAGGCTGAATAGATTCCACAACCTGGTTTGCCAGTTCATCTTTTGACTCTATTAAAATCTTCAATAGTTGTTATTCTGTA
GTTTCACTCTCATGAGTGCAACTGTGGCTTAGCTAATATTGCAATGTGGCTTGAATGTAGGTAGCATCCTTTGATGCTTCTTTGAAACTT
GTATGAATTTGGGTATGAACAGATTGCCTGCTTTCCCTTAAATAACACTTAGATTTATTGGACCAGTCAGCACAGCATGCCTGGTTGTAT
TAAAGCAGGGATATGCTGTATTTTATAAAATTGGCAAAATTAGAGAAATATAGTTCACAATGAAATTATATTTTCTTTGTAAAGAAAGTG
GCTTGAAATCTTTTTTGTTCAAAGATTAATGCCAACTCTTAAGATTATTCTTTCACCAACTATAGAATGTATTTTATATATCGTTCATTG
TAAAAAGCCCTTAAAAATATGTGTATACTACTTTGGCTCTTGTGCATAAAAACAAGAACACTGAAAATTGGGAATATGCACAAACTTGGC
TTCTTTAACCAAGAATATTATTGGAAAATTCTCTAAAAGTTAATAGGGTAAATTCTCTATTTTTTGTAATGTGTTCGGTGATTTCAGAAA
GCTAGAAAGTGTATGTGTGGCATTTGTTTTCACTTTTTAAAACATCCCTAACTGATCGAATATATCAGTAATTTCAGAATCAGATGCATC
CTTTCATAAGAAGTGAGAGGACTCTGACAGCCATAACAGGAGTGCCACTTCATGGTGCGAAGTGAACACTGTAGTCTTGTTGTTTTCCCA
AAGAGAACTCCGTATGTTCTCTTAGGTTGAGTAACCCACTCTGAATTCTGGTTACATGTGTTTTTCTCTCCCTCCTTAAATAAAGAGAGG
GGTTAAACATGCCCTCTAAAAGTAGGTGGTTTTGAAGAGAATAAATTCATCAGATAACCTCAAGTCACATGAGAATCTTAGTCCATTTAC
ATTGCCTTGGCTAGTAAAAGCCATCTATGTATATGTCTTACCTCATCTCCTAAAAGGCAGAGTACAAAGTAAGCCATGTATCTCAGGAAG
GTAACTTCATTTTGTCTATTTGCTGTTGATTGTACCAAGGGATGGAAGAAGTAAATATAGCTCAGGTAGCACTTTATACTCAGGCAGATC
TCAGCCCTCTACTGAGTCCCTTAGCCAAGCAGTTTCTTTCAAAGAAGCCAGCAGGCGAAAAGCAGGGACTGCCACTGCATTTCATATCAC
ACTGTTAAAAGTTGTGTTTTGAAATTTTATGTTTAGTTGCACAAATTGGGCCAAAGAAACATTGCCTTGAGGAAGATATGATTGGAAAAT
CAAGAGTGTAGAAGAATAAATACTGTTTTACTGTCCAAAGACATGTTTATAGTGCTCTGTAAATGTTCCTTTCCTTTGTAGTCTCTGGCA
AGATGCTTTAGGAAGATAAAAGTTTGAGGAGAACAAACAGGAATTCTGAATTAAGCACAGAGTTGAAGTTTATACCCGTTTCACATGCTT
TTCAAGAATGTCGCAATTACTAAGAAGCAGATAATGGTGTTTTTTAGAAACCTAATTGAAGTATATTCAACCAAATACTTTAATGTATAA
AATAAATATTATACAATATACTTGTATAGCAGTTTCTGCTTCACATTTGATTTTTTCAAATTTAATATTTATATTAGAGATCTATATATG
TATAAATATGTATTTTGTCAAATTTGTTACTTAAATATATAGAGACCAGTTTTCTCTGGAAGTTTGTTTAAATGACAGAAGCGTATATGA
ATTCAAGAAAATTTAAGCTGCAAAAATGTATTTGCTATAAAATGAGAAGTCTCACTGATAGAGGTTCTTTATTGCTCATTTTTTAAAAAA

>In-frame_ENST00000418917_ENST00000354848_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(amino acids)=241AA_start in transcript=102_stop in transcript=827
MESTMNGQLDLSGKLIIKAQLGEDIRRIPIHNEDITYDELVLMMQRVFRGKLLSNDEVTIKYKDEDGDLITIFDSSDLSFAIQCSRILKL
TLFVNGQPRPLESSQVKYLRRELIELRNKVNRLLDSLEPPGEPGPSTNIPENVSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGI

--------------------------------------------------------------
>In-frame_ENST00000418917_ENST00000441839_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(transcript)=2686nt_BP=529nt
AGGGACTCTTCGGCCTAGGCAGCCGGGACCCAGCCAGCCCTGCGCCTCGCGCCGTCGCGCATGCGTCCTGGTCTTTCTCTAGAGTTGTAT
ATATAGAACATCCTGGAGTCCACCATGAACGGACAGTTGGATCTAAGTGGGAAGCTAATCATCAAAGCTCAACTTGGGGAGGATATTCGG
CGAATTCCTATTCATAATGAAGATATTACTTATGATGAATTAGTGCTAATGATGCAACGAGTTTTCAGAGGAAAACTTCTGAGTAATGAT
GAAGTAACAATAAAGTATAAAGATGAAGATGGAGATCTTATAACAATTTTTGATAGTTCTGACCTTTCCTTTGCAATTCAGTGCAGTAGG
ATACTGAAACTGACATTATTTGTTAATGGCCAGCCAAGACCCCTTGAATCAAGTCAGGTGAAATATCTCCGTCGAGAACTGATAGAACTT
CGAAATAAAGTGAATCGTTTATTGGATAGCTTGGAACCACCTGGAGAACCAGGACCTTCCACCAATATTCCTGAAAATGTGTCGACTTCT
TCCACTACAAAATCTCCAGCGTCCAGTGCCTCAGGTCCTAGGCCTACTTACAAGCCTCCAGTCTCAAATTATCCAGGATATCCTAAACCT
GAGGAAGGAATACTTGACAGTTTGGATGTTTGGGTCATTGCTGTGATTGTTATTGCCATAGGAAAGCAGATGGTGGAGCTGAATATGCCA
CTTACCAGACTAAATCAACCACTCCAGCAGAGCAGAGAGGCTGAATAGATTCCACAACCTGGTTTGCCAGTTCATCTTTTGACTCTATTA
AAATCTTCAATAGTTGTTATTCTGTAGTTTCACTCTCATGAGTGCAACTGTGGCTTAGCTAATATTGCAATGTGGCTTGAATGTAGGTAG
CATCCTTTGATGCTTCTTTGAAACTTGTATGAATTTGGGTATGAACAGATTGCCTGCTTTCCCTTAAATAACACTTAGATTTATTGGACC
AGTCAGCACAGCATGCCTGGTTGTATTAAAGCAGGGATATGCTGTATTTTATAAAATTGGCAAAATTAGAGAAATATAGTTCACAATGAA
ATTATATTTTCTTTGTAAAGAAAGTGGCTTGAAATCTTTTTTGTTCAAAGATTAATGCCAACTCTTAAGATTATTCTTTCACCAACTATA
GAATGTATTTTATATATCGTTCATTGTAAAAAGCCCTTAAAAATATGTGTATACTACTTTGGCTCTTGTGCATAAAAACAAGAACACTGA
AAATTGGGAATATGCACAAACTTGGCTTCTTTAACCAAGAATATTATTGGAAAATTCTCTAAAAGTTAATAGGGTAAATTCTCTATTTTT
TGTAATGTGTTCGGTGATTTCAGAAAGCTAGAAAGTGTATGTGTGGCATTTGTTTTCACTTTTTAAAACATCCCTAACTGATCGAATATA
TCAGTAATTTCAGAATCAGATGCATCCTTTCATAAGAAGTGAGAGGACTCTGACAGCCATAACAGGAGTGCCACTTCATGGTGCGAAGTG
AACACTGTAGTCTTGTTGTTTTCCCAAAGAGAACTCCGTATGTTCTCTTAGGTTGAGTAACCCACTCTGAATTCTGGTTACATGTGTTTT
TCTCTCCCTCCTTAAATAAAGAGAGGGGTTAAACATGCCCTCTAAAAGTAGGTGGTTTTGAAGAGAATAAATTCATCAGATAACCTCAAG
TCACATGAGAATCTTAGTCCATTTACATTGCCTTGGCTAGTAAAAGCCATCTATGTATATGTCTTACCTCATCTCCTAAAAGGCAGAGTA
CAAAGTAAGCCATGTATCTCAGGAAGGTAACTTCATTTTGTCTATTTGCTGTTGATTGTACCAAGGGATGGAAGAAGTAAATATAGCTCA
GGTAGCACTTTATACTCAGGCAGATCTCAGCCCTCTACTGAGTCCCTTAGCCAAGCAGTTTCTTTCAAAGAAGCCAGCAGGCGAAAAGCA
GGGACTGCCACTGCATTTCATATCACACTGTTAAAAGTTGTGTTTTGAAATTTTATGTTTAGTTGCACAAATTGGGCCAAAGAAACATTG
CCTTGAGGAAGATATGATTGGAAAATCAAGAGTGTAGAAGAATAAATACTGTTTTACTGTCCAAAGACATGTTTATAGTGCTCTGTAAAT
GTTCCTTTCCTTTGTAGTCTCTGGCAAGATGCTTTAGGAAGATAAAAGTTTGAGGAGAACAAACAGGAATTCTGAATTAAGCACAGAGTT
GAAGTTTATACCCGTTTCACATGCTTTTCAAGAATGTCGCAATTACTAAGAAGCAGATAATGGTGTTTTTTAGAAACCTAATTGAAGTAT
ATTCAACCAAATACTTTAATGTATAAAATAAATATTATACAATATACTTGTATAGCAGTTTCTGCTTCACATTTGATTTTTTCAAATTTA
ATATTTATATTAGAGATCTATATATGTATAAATATGTATTTTGTCAAATTTGTTACTTAAATATATAGAGACCAGTTTTCTCTGGAAGTT
TGTTTAAATGACAGAAGCGTATATGAATTCAAGAAAATTTAAGCTGCAAAAATGTATTTGCTATAAAATGAGAAGTCTCACTGATAGAGG

>In-frame_ENST00000418917_ENST00000441839_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(amino acids)=221AA_start in transcript=102_stop in transcript=767
MESTMNGQLDLSGKLIIKAQLGEDIRRIPIHNEDITYDELVLMMQRVFRGKLLSNDEVTIKYKDEDGDLITIFDSSDLSFAIQCSRILKL
TLFVNGQPRPLESSQVKYLRRELIELRNKVNRLLDSLEPPGEPGPSTNIPENVSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGI

--------------------------------------------------------------
>In-frame_ENST00000418917_ENST00000322875_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(transcript)=2750nt_BP=529nt
AGGGACTCTTCGGCCTAGGCAGCCGGGACCCAGCCAGCCCTGCGCCTCGCGCCGTCGCGCATGCGTCCTGGTCTTTCTCTAGAGTTGTAT
ATATAGAACATCCTGGAGTCCACCATGAACGGACAGTTGGATCTAAGTGGGAAGCTAATCATCAAAGCTCAACTTGGGGAGGATATTCGG
CGAATTCCTATTCATAATGAAGATATTACTTATGATGAATTAGTGCTAATGATGCAACGAGTTTTCAGAGGAAAACTTCTGAGTAATGAT
GAAGTAACAATAAAGTATAAAGATGAAGATGGAGATCTTATAACAATTTTTGATAGTTCTGACCTTTCCTTTGCAATTCAGTGCAGTAGG
ATACTGAAACTGACATTATTTGTTAATGGCCAGCCAAGACCCCTTGAATCAAGTCAGGTGAAATATCTCCGTCGAGAACTGATAGAACTT
CGAAATAAAGTGAATCGTTTATTGGATAGCTTGGAACCACCTGGAGAACCAGGACCTTCCACCAATATTCCTGAAAATGTGTCGACTTCT
TCCACTACAAAATCTCCAGCGTCCAGTGCCTCAGGTCCTAGGCCTACTTACAAGCCTCCAGTCTCAAATTATCCAGGATATCCTAAACCT
GAGGAAGGAATACTTGACAGTTTGGATGTTTGGGTCATTGCTGTGATTGTTATTGCCATAGTTGTTGGAGTTGCAGTAATTTGTGTTGTC
CCGTACAGATATCTTCAAAGGAGGAAGAAGAAAGGGAAAGCAGATGGTGGAGCTGAATATGCCACTTACCAGACTAAATCAACCACTCCA
GCAGAGCAGAGAGGCTGAATAGATTCCACAACCTGGTTTGCCAGTTCATCTTTTGACTCTATTAAAATCTTCAATAGTTGTTATTCTGTA
GTTTCACTCTCATGAGTGCAACTGTGGCTTAGCTAATATTGCAATGTGGCTTGAATGTAGGTAGCATCCTTTGATGCTTCTTTGAAACTT
GTATGAATTTGGGTATGAACAGATTGCCTGCTTTCCCTTAAATAACACTTAGATTTATTGGACCAGTCAGCACAGCATGCCTGGTTGTAT
TAAAGCAGGGATATGCTGTATTTTATAAAATTGGCAAAATTAGAGAAATATAGTTCACAATGAAATTATATTTTCTTTGTAAAGAAAGTG
GCTTGAAATCTTTTTTGTTCAAAGATTAATGCCAACTCTTAAGATTATTCTTTCACCAACTATAGAATGTATTTTATATATCGTTCATTG
TAAAAAGCCCTTAAAAATATGTGTATACTACTTTGGCTCTTGTGCATAAAAACAAGAACACTGAAAATTGGGAATATGCACAAACTTGGC
TTCTTTAACCAAGAATATTATTGGAAAATTCTCTAAAAGTTAATAGGGTAAATTCTCTATTTTTTGTAATGTGTTCGGTGATTTCAGAAA
GCTAGAAAGTGTATGTGTGGCATTTGTTTTCACTTTTTAAAACATCCCTAACTGATCGAATATATCAGTAATTTCAGAATCAGATGCATC
CTTTCATAAGAAGTGAGAGGACTCTGACAGCCATAACAGGAGTGCCACTTCATGGTGCGAAGTGAACACTGTAGTCTTGTTGTTTTCCCA
AAGAGAACTCCGTATGTTCTCTTAGGTTGAGTAACCCACTCTGAATTCTGGTTACATGTGTTTTTCTCTCCCTCCTTAAATAAAGAGAGG
GGTTAAACATGCCCTCTAAAAGTAGGTGGTTTTGAAGAGAATAAATTCATCAGATAACCTCAAGTCACATGAGAATCTTAGTCCATTTAC
ATTGCCTTGGCTAGTAAAAGCCATCTATGTATATGTCTTACCTCATCTCCTAAAAGGCAGAGTACAAAGTAAGCCATGTATCTCAGGAAG
GTAACTTCATTTTGTCTATTTGCTGTTGATTGTACCAAGGGATGGAAGAAGTAAATATAGCTCAGGTAGCACTTTATACTCAGGCAGATC
TCAGCCCTCTACTGAGTCCCTTAGCCAAGCAGTTTCTTTCAAAGAAGCCAGCAGGCGAAAAGCAGGGACTGCCACTGCATTTCATATCAC
ACTGTTAAAAGTTGTGTTTTGAAATTTTATGTTTAGTTGCACAAATTGGGCCAAAGAAACATTGCCTTGAGGAAGATATGATTGGAAAAT
CAAGAGTGTAGAAGAATAAATACTGTTTTACTGTCCAAAGACATGTTTATAGTGCTCTGTAAATGTTCCTTTCCTTTGTAGTCTCTGGCA
AGATGCTTTAGGAAGATAAAAGTTTGAGGAGAACAAACAGGAATTCTGAATTAAGCACAGAGTTGAAGTTTATACCCGTTTCACATGCTT
TTCAAGAATGTCGCAATTACTAAGAAGCAGATAATGGTGTTTTTTAGAAACCTAATTGAAGTATATTCAACCAAATACTTTAATGTATAA
AATAAATATTATACAATATACTTGTATAGCAGTTTCTGCTTCACATTTGATTTTTTCAAATTTAATATTTATATTAGAGATCTATATATG
TATAAATATGTATTTTGTCAAATTTGTTACTTAAATATATAGAGACCAGTTTTCTCTGGAAGTTTGTTTAAATGACAGAAGCGTATATGA
ATTCAAGAAAATTTAAGCTGCAAAAATGTATTTGCTATAAAATGAGAAGTCTCACTGATAGAGGTTCTTTATTGCTCATTTTTTAAAAAA

>In-frame_ENST00000418917_ENST00000322875_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(amino acids)=241AA_start in transcript=102_stop in transcript=827
MESTMNGQLDLSGKLIIKAQLGEDIRRIPIHNEDITYDELVLMMQRVFRGKLLSNDEVTIKYKDEDGDLITIFDSSDLSFAIQCSRILKL
TLFVNGQPRPLESSQVKYLRRELIELRNKVNRLLDSLEPPGEPGPSTNIPENVSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGI

--------------------------------------------------------------
>In-frame_ENST00000490574_ENST00000367042_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(transcript)=2826nt_BP=512nt
GGCAGCCGGGACCCAGCCAGCCCTGCGCCTCGCGCCGTCGCGCATGCGTCCTGGTCTTTCTCTAGAGTTGTATATATAGAACATCCTGGA
GTCCACCATGAACGGACAGTTGGATCTAAGTGGGAAGCTAATCATCAAAGCTCAACTTGGGGAGGATATTCGGCGAATTCCTATTCATAA
TGAAGATATTACTTATGATGAATTAGTGCTAATGATGCAACGAGTTTTCAGAGGAAAACTTCTGAGTAATGATGAAGTAACAATAAAGTA
TAAAGATGAAGATGGAGATCTTATAACAATTTTTGATAGTTCTGACCTTTCCTTTGCAATTCAGTGCAGTAGGATACTGAAACTGACATT
ATTTGTTAATGGCCAGCCAAGACCCCTTGAATCAAGTCAGGTGAAATATCTCCGTCGAGAACTGATAGAACTTCGAAATAAAGTGAATCG
TTTATTGGATAGCTTGGAACCACCTGGAGAACCAGGACCTTCCACCAATATTCCTGAAAATGTGTCGACTTCTTCCACTACAAAATCTCC
AGCGTCCAGTGCCTCAGGTCCTAGGCCTACTTACAAGCCTCCAGTCTCAAATTATCCAGGATATCCTAAACCTGAGGAAGGAATACTTGA
CAGTTTGGATGTTTGGGTCATTGCTGTGATTGTTATTGCCATAGTTGTTGGAGTTGCAGTAATTTGTGTTGTCCCGTACAGATATCTTCA
AAGGAGGAAGAAGAAAGGCACATACCTAACTGATGAGACCCACAGAGAAGTAAAATTTACTTCTCTCTGAGAAGGAGAGATGAGAGAAAG
GTTTGCTTTTATCATTAAAAGGAAAGCAGATGGTGGAGCTGAATATGCCACTTACCAGACTAAATCAACCACTCCAGCAGAGCAGAGAGG
CTGAATAGATTCCACAACCTGGTTTGCCAGTTCATCTTTTGACTCTATTAAAATCTTCAATAGTTGTTATTCTGTAGTTTCACTCTCATG
AGTGCAACTGTGGCTTAGCTAATATTGCAATGTGGCTTGAATGTAGGTAGCATCCTTTGATGCTTCTTTGAAACTTGTATGAATTTGGGT
ATGAACAGATTGCCTGCTTTCCCTTAAATAACACTTAGATTTATTGGACCAGTCAGCACAGCATGCCTGGTTGTATTAAAGCAGGGATAT
GCTGTATTTTATAAAATTGGCAAAATTAGAGAAATATAGTTCACAATGAAATTATATTTTCTTTGTAAAGAAAGTGGCTTGAAATCTTTT
TTGTTCAAAGATTAATGCCAACTCTTAAGATTATTCTTTCACCAACTATAGAATGTATTTTATATATCGTTCATTGTAAAAAGCCCTTAA
AAATATGTGTATACTACTTTGGCTCTTGTGCATAAAAACAAGAACACTGAAAATTGGGAATATGCACAAACTTGGCTTCTTTAACCAAGA
ATATTATTGGAAAATTCTCTAAAAGTTAATAGGGTAAATTCTCTATTTTTTGTAATGTGTTCGGTGATTTCAGAAAGCTAGAAAGTGTAT
GTGTGGCATTTGTTTTCACTTTTTAAAACATCCCTAACTGATCGAATATATCAGTAATTTCAGAATCAGATGCATCCTTTCATAAGAAGT
GAGAGGACTCTGACAGCCATAACAGGAGTGCCACTTCATGGTGCGAAGTGAACACTGTAGTCTTGTTGTTTTCCCAAAGAGAACTCCGTA
TGTTCTCTTAGGTTGAGTAACCCACTCTGAATTCTGGTTACATGTGTTTTTCTCTCCCTCCTTAAATAAAGAGAGGGGTTAAACATGCCC
TCTAAAAGTAGGTGGTTTTGAAGAGAATAAATTCATCAGATAACCTCAAGTCACATGAGAATCTTAGTCCATTTACATTGCCTTGGCTAG
TAAAAGCCATCTATGTATATGTCTTACCTCATCTCCTAAAAGGCAGAGTACAAAGTAAGCCATGTATCTCAGGAAGGTAACTTCATTTTG
TCTATTTGCTGTTGATTGTACCAAGGGATGGAAGAAGTAAATATAGCTCAGGTAGCACTTTATACTCAGGCAGATCTCAGCCCTCTACTG
AGTCCCTTAGCCAAGCAGTTTCTTTCAAAGAAGCCAGCAGGCGAAAAGCAGGGACTGCCACTGCATTTCATATCACACTGTTAAAAGTTG
TGTTTTGAAATTTTATGTTTAGTTGCACAAATTGGGCCAAAGAAACATTGCCTTGAGGAAGATATGATTGGAAAATCAAGAGTGTAGAAG
AATAAATACTGTTTTACTGTCCAAAGACATGTTTATAGTGCTCTGTAAATGTTCCTTTCCTTTGTAGTCTCTGGCAAGATGCTTTAGGAA
GATAAAAGTTTGAGGAGAACAAACAGGAATTCTGAATTAAGCACAGAGTTGAAGTTTATACCCGTTTCACATGCTTTTCAAGAATGTCGC
AATTACTAAGAAGCAGATAATGGTGTTTTTTAGAAACCTAATTGAAGTATATTCAACCAAATACTTTAATGTATAAAATAAATATTATAC
AATATACTTGTATAGCAGTTTCTGCTTCACATTTGATTTTTTCAAATTTAATATTTATATTAGAGATCTATATATGTATAAATATGTATT
TTGTCAAATTTGTTACTTAAATATATAGAGACCAGTTTTCTCTGGAAGTTTGTTTAAATGACAGAAGCGTATATGAATTCAAGAAAATTT
AAGCTGCAAAAATGTATTTGCTATAAAATGAGAAGTCTCACTGATAGAGGTTCTTTATTGCTCATTTTTTAAAAAATGGACTCTTGAAAT

>In-frame_ENST00000490574_ENST00000367042_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(amino acids)=234AA_start in transcript=85_stop in transcript=789
MESTMNGQLDLSGKLIIKAQLGEDIRRIPIHNEDITYDELVLMMQRVFRGKLLSNDEVTIKYKDEDGDLITIFDSSDLSFAIQCSRILKL
TLFVNGQPRPLESSQVKYLRRELIELRNKVNRLLDSLEPPGEPGPSTNIPENVSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGI

--------------------------------------------------------------
>In-frame_ENST00000490574_ENST00000354848_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(transcript)=2733nt_BP=512nt
GGCAGCCGGGACCCAGCCAGCCCTGCGCCTCGCGCCGTCGCGCATGCGTCCTGGTCTTTCTCTAGAGTTGTATATATAGAACATCCTGGA
GTCCACCATGAACGGACAGTTGGATCTAAGTGGGAAGCTAATCATCAAAGCTCAACTTGGGGAGGATATTCGGCGAATTCCTATTCATAA
TGAAGATATTACTTATGATGAATTAGTGCTAATGATGCAACGAGTTTTCAGAGGAAAACTTCTGAGTAATGATGAAGTAACAATAAAGTA
TAAAGATGAAGATGGAGATCTTATAACAATTTTTGATAGTTCTGACCTTTCCTTTGCAATTCAGTGCAGTAGGATACTGAAACTGACATT
ATTTGTTAATGGCCAGCCAAGACCCCTTGAATCAAGTCAGGTGAAATATCTCCGTCGAGAACTGATAGAACTTCGAAATAAAGTGAATCG
TTTATTGGATAGCTTGGAACCACCTGGAGAACCAGGACCTTCCACCAATATTCCTGAAAATGTGTCGACTTCTTCCACTACAAAATCTCC
AGCGTCCAGTGCCTCAGGTCCTAGGCCTACTTACAAGCCTCCAGTCTCAAATTATCCAGGATATCCTAAACCTGAGGAAGGAATACTTGA
CAGTTTGGATGTTTGGGTCATTGCTGTGATTGTTATTGCCATAGTTGTTGGAGTTGCAGTAATTTGTGTTGTCCCGTACAGATATCTTCA
AAGGAGGAAGAAGAAAGGGAAAGCAGATGGTGGAGCTGAATATGCCACTTACCAGACTAAATCAACCACTCCAGCAGAGCAGAGAGGCTG
AATAGATTCCACAACCTGGTTTGCCAGTTCATCTTTTGACTCTATTAAAATCTTCAATAGTTGTTATTCTGTAGTTTCACTCTCATGAGT
GCAACTGTGGCTTAGCTAATATTGCAATGTGGCTTGAATGTAGGTAGCATCCTTTGATGCTTCTTTGAAACTTGTATGAATTTGGGTATG
AACAGATTGCCTGCTTTCCCTTAAATAACACTTAGATTTATTGGACCAGTCAGCACAGCATGCCTGGTTGTATTAAAGCAGGGATATGCT
GTATTTTATAAAATTGGCAAAATTAGAGAAATATAGTTCACAATGAAATTATATTTTCTTTGTAAAGAAAGTGGCTTGAAATCTTTTTTG
TTCAAAGATTAATGCCAACTCTTAAGATTATTCTTTCACCAACTATAGAATGTATTTTATATATCGTTCATTGTAAAAAGCCCTTAAAAA
TATGTGTATACTACTTTGGCTCTTGTGCATAAAAACAAGAACACTGAAAATTGGGAATATGCACAAACTTGGCTTCTTTAACCAAGAATA
TTATTGGAAAATTCTCTAAAAGTTAATAGGGTAAATTCTCTATTTTTTGTAATGTGTTCGGTGATTTCAGAAAGCTAGAAAGTGTATGTG
TGGCATTTGTTTTCACTTTTTAAAACATCCCTAACTGATCGAATATATCAGTAATTTCAGAATCAGATGCATCCTTTCATAAGAAGTGAG
AGGACTCTGACAGCCATAACAGGAGTGCCACTTCATGGTGCGAAGTGAACACTGTAGTCTTGTTGTTTTCCCAAAGAGAACTCCGTATGT
TCTCTTAGGTTGAGTAACCCACTCTGAATTCTGGTTACATGTGTTTTTCTCTCCCTCCTTAAATAAAGAGAGGGGTTAAACATGCCCTCT
AAAAGTAGGTGGTTTTGAAGAGAATAAATTCATCAGATAACCTCAAGTCACATGAGAATCTTAGTCCATTTACATTGCCTTGGCTAGTAA
AAGCCATCTATGTATATGTCTTACCTCATCTCCTAAAAGGCAGAGTACAAAGTAAGCCATGTATCTCAGGAAGGTAACTTCATTTTGTCT
ATTTGCTGTTGATTGTACCAAGGGATGGAAGAAGTAAATATAGCTCAGGTAGCACTTTATACTCAGGCAGATCTCAGCCCTCTACTGAGT
CCCTTAGCCAAGCAGTTTCTTTCAAAGAAGCCAGCAGGCGAAAAGCAGGGACTGCCACTGCATTTCATATCACACTGTTAAAAGTTGTGT
TTTGAAATTTTATGTTTAGTTGCACAAATTGGGCCAAAGAAACATTGCCTTGAGGAAGATATGATTGGAAAATCAAGAGTGTAGAAGAAT
AAATACTGTTTTACTGTCCAAAGACATGTTTATAGTGCTCTGTAAATGTTCCTTTCCTTTGTAGTCTCTGGCAAGATGCTTTAGGAAGAT
AAAAGTTTGAGGAGAACAAACAGGAATTCTGAATTAAGCACAGAGTTGAAGTTTATACCCGTTTCACATGCTTTTCAAGAATGTCGCAAT
TACTAAGAAGCAGATAATGGTGTTTTTTAGAAACCTAATTGAAGTATATTCAACCAAATACTTTAATGTATAAAATAAATATTATACAAT
ATACTTGTATAGCAGTTTCTGCTTCACATTTGATTTTTTCAAATTTAATATTTATATTAGAGATCTATATATGTATAAATATGTATTTTG
TCAAATTTGTTACTTAAATATATAGAGACCAGTTTTCTCTGGAAGTTTGTTTAAATGACAGAAGCGTATATGAATTCAAGAAAATTTAAG
CTGCAAAAATGTATTTGCTATAAAATGAGAAGTCTCACTGATAGAGGTTCTTTATTGCTCATTTTTTAAAAAATGGACTCTTGAAATCTG

>In-frame_ENST00000490574_ENST00000354848_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(amino acids)=241AA_start in transcript=85_stop in transcript=810
MESTMNGQLDLSGKLIIKAQLGEDIRRIPIHNEDITYDELVLMMQRVFRGKLLSNDEVTIKYKDEDGDLITIFDSSDLSFAIQCSRILKL
TLFVNGQPRPLESSQVKYLRRELIELRNKVNRLLDSLEPPGEPGPSTNIPENVSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGI

--------------------------------------------------------------
>In-frame_ENST00000490574_ENST00000441839_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(transcript)=2669nt_BP=512nt
GGCAGCCGGGACCCAGCCAGCCCTGCGCCTCGCGCCGTCGCGCATGCGTCCTGGTCTTTCTCTAGAGTTGTATATATAGAACATCCTGGA
GTCCACCATGAACGGACAGTTGGATCTAAGTGGGAAGCTAATCATCAAAGCTCAACTTGGGGAGGATATTCGGCGAATTCCTATTCATAA
TGAAGATATTACTTATGATGAATTAGTGCTAATGATGCAACGAGTTTTCAGAGGAAAACTTCTGAGTAATGATGAAGTAACAATAAAGTA
TAAAGATGAAGATGGAGATCTTATAACAATTTTTGATAGTTCTGACCTTTCCTTTGCAATTCAGTGCAGTAGGATACTGAAACTGACATT
ATTTGTTAATGGCCAGCCAAGACCCCTTGAATCAAGTCAGGTGAAATATCTCCGTCGAGAACTGATAGAACTTCGAAATAAAGTGAATCG
TTTATTGGATAGCTTGGAACCACCTGGAGAACCAGGACCTTCCACCAATATTCCTGAAAATGTGTCGACTTCTTCCACTACAAAATCTCC
AGCGTCCAGTGCCTCAGGTCCTAGGCCTACTTACAAGCCTCCAGTCTCAAATTATCCAGGATATCCTAAACCTGAGGAAGGAATACTTGA
CAGTTTGGATGTTTGGGTCATTGCTGTGATTGTTATTGCCATAGGAAAGCAGATGGTGGAGCTGAATATGCCACTTACCAGACTAAATCA
ACCACTCCAGCAGAGCAGAGAGGCTGAATAGATTCCACAACCTGGTTTGCCAGTTCATCTTTTGACTCTATTAAAATCTTCAATAGTTGT
TATTCTGTAGTTTCACTCTCATGAGTGCAACTGTGGCTTAGCTAATATTGCAATGTGGCTTGAATGTAGGTAGCATCCTTTGATGCTTCT
TTGAAACTTGTATGAATTTGGGTATGAACAGATTGCCTGCTTTCCCTTAAATAACACTTAGATTTATTGGACCAGTCAGCACAGCATGCC
TGGTTGTATTAAAGCAGGGATATGCTGTATTTTATAAAATTGGCAAAATTAGAGAAATATAGTTCACAATGAAATTATATTTTCTTTGTA
AAGAAAGTGGCTTGAAATCTTTTTTGTTCAAAGATTAATGCCAACTCTTAAGATTATTCTTTCACCAACTATAGAATGTATTTTATATAT
CGTTCATTGTAAAAAGCCCTTAAAAATATGTGTATACTACTTTGGCTCTTGTGCATAAAAACAAGAACACTGAAAATTGGGAATATGCAC
AAACTTGGCTTCTTTAACCAAGAATATTATTGGAAAATTCTCTAAAAGTTAATAGGGTAAATTCTCTATTTTTTGTAATGTGTTCGGTGA
TTTCAGAAAGCTAGAAAGTGTATGTGTGGCATTTGTTTTCACTTTTTAAAACATCCCTAACTGATCGAATATATCAGTAATTTCAGAATC
AGATGCATCCTTTCATAAGAAGTGAGAGGACTCTGACAGCCATAACAGGAGTGCCACTTCATGGTGCGAAGTGAACACTGTAGTCTTGTT
GTTTTCCCAAAGAGAACTCCGTATGTTCTCTTAGGTTGAGTAACCCACTCTGAATTCTGGTTACATGTGTTTTTCTCTCCCTCCTTAAAT
AAAGAGAGGGGTTAAACATGCCCTCTAAAAGTAGGTGGTTTTGAAGAGAATAAATTCATCAGATAACCTCAAGTCACATGAGAATCTTAG
TCCATTTACATTGCCTTGGCTAGTAAAAGCCATCTATGTATATGTCTTACCTCATCTCCTAAAAGGCAGAGTACAAAGTAAGCCATGTAT
CTCAGGAAGGTAACTTCATTTTGTCTATTTGCTGTTGATTGTACCAAGGGATGGAAGAAGTAAATATAGCTCAGGTAGCACTTTATACTC
AGGCAGATCTCAGCCCTCTACTGAGTCCCTTAGCCAAGCAGTTTCTTTCAAAGAAGCCAGCAGGCGAAAAGCAGGGACTGCCACTGCATT
TCATATCACACTGTTAAAAGTTGTGTTTTGAAATTTTATGTTTAGTTGCACAAATTGGGCCAAAGAAACATTGCCTTGAGGAAGATATGA
TTGGAAAATCAAGAGTGTAGAAGAATAAATACTGTTTTACTGTCCAAAGACATGTTTATAGTGCTCTGTAAATGTTCCTTTCCTTTGTAG
TCTCTGGCAAGATGCTTTAGGAAGATAAAAGTTTGAGGAGAACAAACAGGAATTCTGAATTAAGCACAGAGTTGAAGTTTATACCCGTTT
CACATGCTTTTCAAGAATGTCGCAATTACTAAGAAGCAGATAATGGTGTTTTTTAGAAACCTAATTGAAGTATATTCAACCAAATACTTT
AATGTATAAAATAAATATTATACAATATACTTGTATAGCAGTTTCTGCTTCACATTTGATTTTTTCAAATTTAATATTTATATTAGAGAT
CTATATATGTATAAATATGTATTTTGTCAAATTTGTTACTTAAATATATAGAGACCAGTTTTCTCTGGAAGTTTGTTTAAATGACAGAAG
CGTATATGAATTCAAGAAAATTTAAGCTGCAAAAATGTATTTGCTATAAAATGAGAAGTCTCACTGATAGAGGTTCTTTATTGCTCATTT

>In-frame_ENST00000490574_ENST00000441839_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(amino acids)=221AA_start in transcript=85_stop in transcript=750
MESTMNGQLDLSGKLIIKAQLGEDIRRIPIHNEDITYDELVLMMQRVFRGKLLSNDEVTIKYKDEDGDLITIFDSSDLSFAIQCSRILKL
TLFVNGQPRPLESSQVKYLRRELIELRNKVNRLLDSLEPPGEPGPSTNIPENVSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGI

--------------------------------------------------------------
>In-frame_ENST00000490574_ENST00000322875_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(transcript)=2733nt_BP=512nt
GGCAGCCGGGACCCAGCCAGCCCTGCGCCTCGCGCCGTCGCGCATGCGTCCTGGTCTTTCTCTAGAGTTGTATATATAGAACATCCTGGA
GTCCACCATGAACGGACAGTTGGATCTAAGTGGGAAGCTAATCATCAAAGCTCAACTTGGGGAGGATATTCGGCGAATTCCTATTCATAA
TGAAGATATTACTTATGATGAATTAGTGCTAATGATGCAACGAGTTTTCAGAGGAAAACTTCTGAGTAATGATGAAGTAACAATAAAGTA
TAAAGATGAAGATGGAGATCTTATAACAATTTTTGATAGTTCTGACCTTTCCTTTGCAATTCAGTGCAGTAGGATACTGAAACTGACATT
ATTTGTTAATGGCCAGCCAAGACCCCTTGAATCAAGTCAGGTGAAATATCTCCGTCGAGAACTGATAGAACTTCGAAATAAAGTGAATCG
TTTATTGGATAGCTTGGAACCACCTGGAGAACCAGGACCTTCCACCAATATTCCTGAAAATGTGTCGACTTCTTCCACTACAAAATCTCC
AGCGTCCAGTGCCTCAGGTCCTAGGCCTACTTACAAGCCTCCAGTCTCAAATTATCCAGGATATCCTAAACCTGAGGAAGGAATACTTGA
CAGTTTGGATGTTTGGGTCATTGCTGTGATTGTTATTGCCATAGTTGTTGGAGTTGCAGTAATTTGTGTTGTCCCGTACAGATATCTTCA
AAGGAGGAAGAAGAAAGGGAAAGCAGATGGTGGAGCTGAATATGCCACTTACCAGACTAAATCAACCACTCCAGCAGAGCAGAGAGGCTG
AATAGATTCCACAACCTGGTTTGCCAGTTCATCTTTTGACTCTATTAAAATCTTCAATAGTTGTTATTCTGTAGTTTCACTCTCATGAGT
GCAACTGTGGCTTAGCTAATATTGCAATGTGGCTTGAATGTAGGTAGCATCCTTTGATGCTTCTTTGAAACTTGTATGAATTTGGGTATG
AACAGATTGCCTGCTTTCCCTTAAATAACACTTAGATTTATTGGACCAGTCAGCACAGCATGCCTGGTTGTATTAAAGCAGGGATATGCT
GTATTTTATAAAATTGGCAAAATTAGAGAAATATAGTTCACAATGAAATTATATTTTCTTTGTAAAGAAAGTGGCTTGAAATCTTTTTTG
TTCAAAGATTAATGCCAACTCTTAAGATTATTCTTTCACCAACTATAGAATGTATTTTATATATCGTTCATTGTAAAAAGCCCTTAAAAA
TATGTGTATACTACTTTGGCTCTTGTGCATAAAAACAAGAACACTGAAAATTGGGAATATGCACAAACTTGGCTTCTTTAACCAAGAATA
TTATTGGAAAATTCTCTAAAAGTTAATAGGGTAAATTCTCTATTTTTTGTAATGTGTTCGGTGATTTCAGAAAGCTAGAAAGTGTATGTG
TGGCATTTGTTTTCACTTTTTAAAACATCCCTAACTGATCGAATATATCAGTAATTTCAGAATCAGATGCATCCTTTCATAAGAAGTGAG
AGGACTCTGACAGCCATAACAGGAGTGCCACTTCATGGTGCGAAGTGAACACTGTAGTCTTGTTGTTTTCCCAAAGAGAACTCCGTATGT
TCTCTTAGGTTGAGTAACCCACTCTGAATTCTGGTTACATGTGTTTTTCTCTCCCTCCTTAAATAAAGAGAGGGGTTAAACATGCCCTCT
AAAAGTAGGTGGTTTTGAAGAGAATAAATTCATCAGATAACCTCAAGTCACATGAGAATCTTAGTCCATTTACATTGCCTTGGCTAGTAA
AAGCCATCTATGTATATGTCTTACCTCATCTCCTAAAAGGCAGAGTACAAAGTAAGCCATGTATCTCAGGAAGGTAACTTCATTTTGTCT
ATTTGCTGTTGATTGTACCAAGGGATGGAAGAAGTAAATATAGCTCAGGTAGCACTTTATACTCAGGCAGATCTCAGCCCTCTACTGAGT
CCCTTAGCCAAGCAGTTTCTTTCAAAGAAGCCAGCAGGCGAAAAGCAGGGACTGCCACTGCATTTCATATCACACTGTTAAAAGTTGTGT
TTTGAAATTTTATGTTTAGTTGCACAAATTGGGCCAAAGAAACATTGCCTTGAGGAAGATATGATTGGAAAATCAAGAGTGTAGAAGAAT
AAATACTGTTTTACTGTCCAAAGACATGTTTATAGTGCTCTGTAAATGTTCCTTTCCTTTGTAGTCTCTGGCAAGATGCTTTAGGAAGAT
AAAAGTTTGAGGAGAACAAACAGGAATTCTGAATTAAGCACAGAGTTGAAGTTTATACCCGTTTCACATGCTTTTCAAGAATGTCGCAAT
TACTAAGAAGCAGATAATGGTGTTTTTTAGAAACCTAATTGAAGTATATTCAACCAAATACTTTAATGTATAAAATAAATATTATACAAT
ATACTTGTATAGCAGTTTCTGCTTCACATTTGATTTTTTCAAATTTAATATTTATATTAGAGATCTATATATGTATAAATATGTATTTTG
TCAAATTTGTTACTTAAATATATAGAGACCAGTTTTCTCTGGAAGTTTGTTTAAATGACAGAAGCGTATATGAATTCAAGAAAATTTAAG
CTGCAAAAATGTATTTGCTATAAAATGAGAAGTCTCACTGATAGAGGTTCTTTATTGCTCATTTTTTAAAAAATGGACTCTTGAAATCTG

>In-frame_ENST00000490574_ENST00000322875_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(amino acids)=241AA_start in transcript=85_stop in transcript=810
MESTMNGQLDLSGKLIIKAQLGEDIRRIPIHNEDITYDELVLMMQRVFRGKLLSNDEVTIKYKDEDGDLITIFDSSDLSFAIQCSRILKL
TLFVNGQPRPLESSQVKYLRRELIELRNKVNRLLDSLEPPGEPGPSTNIPENVSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGI

--------------------------------------------------------------
>In-frame_ENST00000240851_ENST00000367042_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(transcript)=3069nt_BP=755nt
GTCCTGGGTATGTCCACGCGCAATAAGGAGGGGCGAAAGGACATTTTTTTTTTTCTTGCTCCCGCCTCTGTTCTTCCCCCACCTGCCACG
TACAGAGCCCAAGTTCTCGCTAGGCTTGTTGGGTCAGCGCGATTGGCCGGGGCCCGCGCGAGCCTGCGAGCGAGGTGCGGCGGTCGCGAA
GGGCAACCGAGGGGGCCGTGACCACCGCCTCCCCGCGACGCCCCAGTCCAGTGGCCTCGCGTCCGCCCATTCAGCGGAGACCTGCGGAGA
GGCGGCGGCCGCGGCCTCCGCAAGCCGTCTTTCTCTAGAGTTGTATATATAGAACATCCTGGAGTCCACCATGAACGGACAGTTGGATCT
AAGTGGGAAGCTAATCATCAAAGCTCAACTTGGGGAGGATATTCGGCGAATTCCTATTCATAATGAAGATATTACTTATGATGAATTAGT
GCTAATGATGCAACGAGTTTTCAGAGGAAAACTTCTGAGTAATGATGAAGTAACAATAAAGTATAAAGATGAAGATGGAGATCTTATAAC
AATTTTTGATAGTTCTGACCTTTCCTTTGCAATTCAGTGCAGTAGGATACTGAAACTGACATTATTTGTTAATGGCCAGCCAAGACCCCT
TGAATCAAGTCAGGTGAAATATCTCCGTCGAGAACTGATAGAACTTCGAAATAAAGTGAATCGTTTATTGGATAGCTTGGAACCACCTGG
AGAACCAGGACCTTCCACCAATATTCCTGAAAATGTGTCGACTTCTTCCACTACAAAATCTCCAGCGTCCAGTGCCTCAGGTCCTAGGCC
TACTTACAAGCCTCCAGTCTCAAATTATCCAGGATATCCTAAACCTGAGGAAGGAATACTTGACAGTTTGGATGTTTGGGTCATTGCTGT
GATTGTTATTGCCATAGTTGTTGGAGTTGCAGTAATTTGTGTTGTCCCGTACAGATATCTTCAAAGGAGGAAGAAGAAAGGCACATACCT
AACTGATGAGACCCACAGAGAAGTAAAATTTACTTCTCTCTGAGAAGGAGAGATGAGAGAAAGGTTTGCTTTTATCATTAAAAGGAAAGC
AGATGGTGGAGCTGAATATGCCACTTACCAGACTAAATCAACCACTCCAGCAGAGCAGAGAGGCTGAATAGATTCCACAACCTGGTTTGC
CAGTTCATCTTTTGACTCTATTAAAATCTTCAATAGTTGTTATTCTGTAGTTTCACTCTCATGAGTGCAACTGTGGCTTAGCTAATATTG
CAATGTGGCTTGAATGTAGGTAGCATCCTTTGATGCTTCTTTGAAACTTGTATGAATTTGGGTATGAACAGATTGCCTGCTTTCCCTTAA
ATAACACTTAGATTTATTGGACCAGTCAGCACAGCATGCCTGGTTGTATTAAAGCAGGGATATGCTGTATTTTATAAAATTGGCAAAATT
AGAGAAATATAGTTCACAATGAAATTATATTTTCTTTGTAAAGAAAGTGGCTTGAAATCTTTTTTGTTCAAAGATTAATGCCAACTCTTA
AGATTATTCTTTCACCAACTATAGAATGTATTTTATATATCGTTCATTGTAAAAAGCCCTTAAAAATATGTGTATACTACTTTGGCTCTT
GTGCATAAAAACAAGAACACTGAAAATTGGGAATATGCACAAACTTGGCTTCTTTAACCAAGAATATTATTGGAAAATTCTCTAAAAGTT
AATAGGGTAAATTCTCTATTTTTTGTAATGTGTTCGGTGATTTCAGAAAGCTAGAAAGTGTATGTGTGGCATTTGTTTTCACTTTTTAAA
ACATCCCTAACTGATCGAATATATCAGTAATTTCAGAATCAGATGCATCCTTTCATAAGAAGTGAGAGGACTCTGACAGCCATAACAGGA
GTGCCACTTCATGGTGCGAAGTGAACACTGTAGTCTTGTTGTTTTCCCAAAGAGAACTCCGTATGTTCTCTTAGGTTGAGTAACCCACTC
TGAATTCTGGTTACATGTGTTTTTCTCTCCCTCCTTAAATAAAGAGAGGGGTTAAACATGCCCTCTAAAAGTAGGTGGTTTTGAAGAGAA
TAAATTCATCAGATAACCTCAAGTCACATGAGAATCTTAGTCCATTTACATTGCCTTGGCTAGTAAAAGCCATCTATGTATATGTCTTAC
CTCATCTCCTAAAAGGCAGAGTACAAAGTAAGCCATGTATCTCAGGAAGGTAACTTCATTTTGTCTATTTGCTGTTGATTGTACCAAGGG
ATGGAAGAAGTAAATATAGCTCAGGTAGCACTTTATACTCAGGCAGATCTCAGCCCTCTACTGAGTCCCTTAGCCAAGCAGTTTCTTTCA
AAGAAGCCAGCAGGCGAAAAGCAGGGACTGCCACTGCATTTCATATCACACTGTTAAAAGTTGTGTTTTGAAATTTTATGTTTAGTTGCA
CAAATTGGGCCAAAGAAACATTGCCTTGAGGAAGATATGATTGGAAAATCAAGAGTGTAGAAGAATAAATACTGTTTTACTGTCCAAAGA
CATGTTTATAGTGCTCTGTAAATGTTCCTTTCCTTTGTAGTCTCTGGCAAGATGCTTTAGGAAGATAAAAGTTTGAGGAGAACAAACAGG
AATTCTGAATTAAGCACAGAGTTGAAGTTTATACCCGTTTCACATGCTTTTCAAGAATGTCGCAATTACTAAGAAGCAGATAATGGTGTT
TTTTAGAAACCTAATTGAAGTATATTCAACCAAATACTTTAATGTATAAAATAAATATTATACAATATACTTGTATAGCAGTTTCTGCTT
CACATTTGATTTTTTCAAATTTAATATTTATATTAGAGATCTATATATGTATAAATATGTATTTTGTCAAATTTGTTACTTAAATATATA
GAGACCAGTTTTCTCTGGAAGTTTGTTTAAATGACAGAAGCGTATATGAATTCAAGAAAATTTAAGCTGCAAAAATGTATTTGCTATAAA
ATGAGAAGTCTCACTGATAGAGGTTCTTTATTGCTCATTTTTTAAAAAATGGACTCTTGAAATCTGTTAAAATAAAATTGTACATTTGGA

>In-frame_ENST00000240851_ENST00000367042_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(amino acids)=234AA_start in transcript=328_stop in transcript=1032
MESTMNGQLDLSGKLIIKAQLGEDIRRIPIHNEDITYDELVLMMQRVFRGKLLSNDEVTIKYKDEDGDLITIFDSSDLSFAIQCSRILKL
TLFVNGQPRPLESSQVKYLRRELIELRNKVNRLLDSLEPPGEPGPSTNIPENVSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGI

--------------------------------------------------------------
>In-frame_ENST00000240851_ENST00000354848_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(transcript)=2976nt_BP=755nt
GTCCTGGGTATGTCCACGCGCAATAAGGAGGGGCGAAAGGACATTTTTTTTTTTCTTGCTCCCGCCTCTGTTCTTCCCCCACCTGCCACG
TACAGAGCCCAAGTTCTCGCTAGGCTTGTTGGGTCAGCGCGATTGGCCGGGGCCCGCGCGAGCCTGCGAGCGAGGTGCGGCGGTCGCGAA
GGGCAACCGAGGGGGCCGTGACCACCGCCTCCCCGCGACGCCCCAGTCCAGTGGCCTCGCGTCCGCCCATTCAGCGGAGACCTGCGGAGA
GGCGGCGGCCGCGGCCTCCGCAAGCCGTCTTTCTCTAGAGTTGTATATATAGAACATCCTGGAGTCCACCATGAACGGACAGTTGGATCT
AAGTGGGAAGCTAATCATCAAAGCTCAACTTGGGGAGGATATTCGGCGAATTCCTATTCATAATGAAGATATTACTTATGATGAATTAGT
GCTAATGATGCAACGAGTTTTCAGAGGAAAACTTCTGAGTAATGATGAAGTAACAATAAAGTATAAAGATGAAGATGGAGATCTTATAAC
AATTTTTGATAGTTCTGACCTTTCCTTTGCAATTCAGTGCAGTAGGATACTGAAACTGACATTATTTGTTAATGGCCAGCCAAGACCCCT
TGAATCAAGTCAGGTGAAATATCTCCGTCGAGAACTGATAGAACTTCGAAATAAAGTGAATCGTTTATTGGATAGCTTGGAACCACCTGG
AGAACCAGGACCTTCCACCAATATTCCTGAAAATGTGTCGACTTCTTCCACTACAAAATCTCCAGCGTCCAGTGCCTCAGGTCCTAGGCC
TACTTACAAGCCTCCAGTCTCAAATTATCCAGGATATCCTAAACCTGAGGAAGGAATACTTGACAGTTTGGATGTTTGGGTCATTGCTGT
GATTGTTATTGCCATAGTTGTTGGAGTTGCAGTAATTTGTGTTGTCCCGTACAGATATCTTCAAAGGAGGAAGAAGAAAGGGAAAGCAGA
TGGTGGAGCTGAATATGCCACTTACCAGACTAAATCAACCACTCCAGCAGAGCAGAGAGGCTGAATAGATTCCACAACCTGGTTTGCCAG
TTCATCTTTTGACTCTATTAAAATCTTCAATAGTTGTTATTCTGTAGTTTCACTCTCATGAGTGCAACTGTGGCTTAGCTAATATTGCAA
TGTGGCTTGAATGTAGGTAGCATCCTTTGATGCTTCTTTGAAACTTGTATGAATTTGGGTATGAACAGATTGCCTGCTTTCCCTTAAATA
ACACTTAGATTTATTGGACCAGTCAGCACAGCATGCCTGGTTGTATTAAAGCAGGGATATGCTGTATTTTATAAAATTGGCAAAATTAGA
GAAATATAGTTCACAATGAAATTATATTTTCTTTGTAAAGAAAGTGGCTTGAAATCTTTTTTGTTCAAAGATTAATGCCAACTCTTAAGA
TTATTCTTTCACCAACTATAGAATGTATTTTATATATCGTTCATTGTAAAAAGCCCTTAAAAATATGTGTATACTACTTTGGCTCTTGTG
CATAAAAACAAGAACACTGAAAATTGGGAATATGCACAAACTTGGCTTCTTTAACCAAGAATATTATTGGAAAATTCTCTAAAAGTTAAT
AGGGTAAATTCTCTATTTTTTGTAATGTGTTCGGTGATTTCAGAAAGCTAGAAAGTGTATGTGTGGCATTTGTTTTCACTTTTTAAAACA
TCCCTAACTGATCGAATATATCAGTAATTTCAGAATCAGATGCATCCTTTCATAAGAAGTGAGAGGACTCTGACAGCCATAACAGGAGTG
CCACTTCATGGTGCGAAGTGAACACTGTAGTCTTGTTGTTTTCCCAAAGAGAACTCCGTATGTTCTCTTAGGTTGAGTAACCCACTCTGA
ATTCTGGTTACATGTGTTTTTCTCTCCCTCCTTAAATAAAGAGAGGGGTTAAACATGCCCTCTAAAAGTAGGTGGTTTTGAAGAGAATAA
ATTCATCAGATAACCTCAAGTCACATGAGAATCTTAGTCCATTTACATTGCCTTGGCTAGTAAAAGCCATCTATGTATATGTCTTACCTC
ATCTCCTAAAAGGCAGAGTACAAAGTAAGCCATGTATCTCAGGAAGGTAACTTCATTTTGTCTATTTGCTGTTGATTGTACCAAGGGATG
GAAGAAGTAAATATAGCTCAGGTAGCACTTTATACTCAGGCAGATCTCAGCCCTCTACTGAGTCCCTTAGCCAAGCAGTTTCTTTCAAAG
AAGCCAGCAGGCGAAAAGCAGGGACTGCCACTGCATTTCATATCACACTGTTAAAAGTTGTGTTTTGAAATTTTATGTTTAGTTGCACAA
ATTGGGCCAAAGAAACATTGCCTTGAGGAAGATATGATTGGAAAATCAAGAGTGTAGAAGAATAAATACTGTTTTACTGTCCAAAGACAT
GTTTATAGTGCTCTGTAAATGTTCCTTTCCTTTGTAGTCTCTGGCAAGATGCTTTAGGAAGATAAAAGTTTGAGGAGAACAAACAGGAAT
TCTGAATTAAGCACAGAGTTGAAGTTTATACCCGTTTCACATGCTTTTCAAGAATGTCGCAATTACTAAGAAGCAGATAATGGTGTTTTT
TAGAAACCTAATTGAAGTATATTCAACCAAATACTTTAATGTATAAAATAAATATTATACAATATACTTGTATAGCAGTTTCTGCTTCAC
ATTTGATTTTTTCAAATTTAATATTTATATTAGAGATCTATATATGTATAAATATGTATTTTGTCAAATTTGTTACTTAAATATATAGAG
ACCAGTTTTCTCTGGAAGTTTGTTTAAATGACAGAAGCGTATATGAATTCAAGAAAATTTAAGCTGCAAAAATGTATTTGCTATAAAATG
AGAAGTCTCACTGATAGAGGTTCTTTATTGCTCATTTTTTAAAAAATGGACTCTTGAAATCTGTTAAAATAAAATTGTACATTTGGAGAT

>In-frame_ENST00000240851_ENST00000354848_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(amino acids)=241AA_start in transcript=328_stop in transcript=1053
MESTMNGQLDLSGKLIIKAQLGEDIRRIPIHNEDITYDELVLMMQRVFRGKLLSNDEVTIKYKDEDGDLITIFDSSDLSFAIQCSRILKL
TLFVNGQPRPLESSQVKYLRRELIELRNKVNRLLDSLEPPGEPGPSTNIPENVSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGI

--------------------------------------------------------------
>In-frame_ENST00000240851_ENST00000441839_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(transcript)=2912nt_BP=755nt
GTCCTGGGTATGTCCACGCGCAATAAGGAGGGGCGAAAGGACATTTTTTTTTTTCTTGCTCCCGCCTCTGTTCTTCCCCCACCTGCCACG
TACAGAGCCCAAGTTCTCGCTAGGCTTGTTGGGTCAGCGCGATTGGCCGGGGCCCGCGCGAGCCTGCGAGCGAGGTGCGGCGGTCGCGAA
GGGCAACCGAGGGGGCCGTGACCACCGCCTCCCCGCGACGCCCCAGTCCAGTGGCCTCGCGTCCGCCCATTCAGCGGAGACCTGCGGAGA
GGCGGCGGCCGCGGCCTCCGCAAGCCGTCTTTCTCTAGAGTTGTATATATAGAACATCCTGGAGTCCACCATGAACGGACAGTTGGATCT
AAGTGGGAAGCTAATCATCAAAGCTCAACTTGGGGAGGATATTCGGCGAATTCCTATTCATAATGAAGATATTACTTATGATGAATTAGT
GCTAATGATGCAACGAGTTTTCAGAGGAAAACTTCTGAGTAATGATGAAGTAACAATAAAGTATAAAGATGAAGATGGAGATCTTATAAC
AATTTTTGATAGTTCTGACCTTTCCTTTGCAATTCAGTGCAGTAGGATACTGAAACTGACATTATTTGTTAATGGCCAGCCAAGACCCCT
TGAATCAAGTCAGGTGAAATATCTCCGTCGAGAACTGATAGAACTTCGAAATAAAGTGAATCGTTTATTGGATAGCTTGGAACCACCTGG
AGAACCAGGACCTTCCACCAATATTCCTGAAAATGTGTCGACTTCTTCCACTACAAAATCTCCAGCGTCCAGTGCCTCAGGTCCTAGGCC
TACTTACAAGCCTCCAGTCTCAAATTATCCAGGATATCCTAAACCTGAGGAAGGAATACTTGACAGTTTGGATGTTTGGGTCATTGCTGT
GATTGTTATTGCCATAGGAAAGCAGATGGTGGAGCTGAATATGCCACTTACCAGACTAAATCAACCACTCCAGCAGAGCAGAGAGGCTGA
ATAGATTCCACAACCTGGTTTGCCAGTTCATCTTTTGACTCTATTAAAATCTTCAATAGTTGTTATTCTGTAGTTTCACTCTCATGAGTG
CAACTGTGGCTTAGCTAATATTGCAATGTGGCTTGAATGTAGGTAGCATCCTTTGATGCTTCTTTGAAACTTGTATGAATTTGGGTATGA
ACAGATTGCCTGCTTTCCCTTAAATAACACTTAGATTTATTGGACCAGTCAGCACAGCATGCCTGGTTGTATTAAAGCAGGGATATGCTG
TATTTTATAAAATTGGCAAAATTAGAGAAATATAGTTCACAATGAAATTATATTTTCTTTGTAAAGAAAGTGGCTTGAAATCTTTTTTGT
TCAAAGATTAATGCCAACTCTTAAGATTATTCTTTCACCAACTATAGAATGTATTTTATATATCGTTCATTGTAAAAAGCCCTTAAAAAT
ATGTGTATACTACTTTGGCTCTTGTGCATAAAAACAAGAACACTGAAAATTGGGAATATGCACAAACTTGGCTTCTTTAACCAAGAATAT
TATTGGAAAATTCTCTAAAAGTTAATAGGGTAAATTCTCTATTTTTTGTAATGTGTTCGGTGATTTCAGAAAGCTAGAAAGTGTATGTGT
GGCATTTGTTTTCACTTTTTAAAACATCCCTAACTGATCGAATATATCAGTAATTTCAGAATCAGATGCATCCTTTCATAAGAAGTGAGA
GGACTCTGACAGCCATAACAGGAGTGCCACTTCATGGTGCGAAGTGAACACTGTAGTCTTGTTGTTTTCCCAAAGAGAACTCCGTATGTT
CTCTTAGGTTGAGTAACCCACTCTGAATTCTGGTTACATGTGTTTTTCTCTCCCTCCTTAAATAAAGAGAGGGGTTAAACATGCCCTCTA
AAAGTAGGTGGTTTTGAAGAGAATAAATTCATCAGATAACCTCAAGTCACATGAGAATCTTAGTCCATTTACATTGCCTTGGCTAGTAAA
AGCCATCTATGTATATGTCTTACCTCATCTCCTAAAAGGCAGAGTACAAAGTAAGCCATGTATCTCAGGAAGGTAACTTCATTTTGTCTA
TTTGCTGTTGATTGTACCAAGGGATGGAAGAAGTAAATATAGCTCAGGTAGCACTTTATACTCAGGCAGATCTCAGCCCTCTACTGAGTC
CCTTAGCCAAGCAGTTTCTTTCAAAGAAGCCAGCAGGCGAAAAGCAGGGACTGCCACTGCATTTCATATCACACTGTTAAAAGTTGTGTT
TTGAAATTTTATGTTTAGTTGCACAAATTGGGCCAAAGAAACATTGCCTTGAGGAAGATATGATTGGAAAATCAAGAGTGTAGAAGAATA
AATACTGTTTTACTGTCCAAAGACATGTTTATAGTGCTCTGTAAATGTTCCTTTCCTTTGTAGTCTCTGGCAAGATGCTTTAGGAAGATA
AAAGTTTGAGGAGAACAAACAGGAATTCTGAATTAAGCACAGAGTTGAAGTTTATACCCGTTTCACATGCTTTTCAAGAATGTCGCAATT
ACTAAGAAGCAGATAATGGTGTTTTTTAGAAACCTAATTGAAGTATATTCAACCAAATACTTTAATGTATAAAATAAATATTATACAATA
TACTTGTATAGCAGTTTCTGCTTCACATTTGATTTTTTCAAATTTAATATTTATATTAGAGATCTATATATGTATAAATATGTATTTTGT
CAAATTTGTTACTTAAATATATAGAGACCAGTTTTCTCTGGAAGTTTGTTTAAATGACAGAAGCGTATATGAATTCAAGAAAATTTAAGC
TGCAAAAATGTATTTGCTATAAAATGAGAAGTCTCACTGATAGAGGTTCTTTATTGCTCATTTTTTAAAAAATGGACTCTTGAAATCTGT

>In-frame_ENST00000240851_ENST00000441839_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(amino acids)=221AA_start in transcript=328_stop in transcript=993
MESTMNGQLDLSGKLIIKAQLGEDIRRIPIHNEDITYDELVLMMQRVFRGKLLSNDEVTIKYKDEDGDLITIFDSSDLSFAIQCSRILKL
TLFVNGQPRPLESSQVKYLRRELIELRNKVNRLLDSLEPPGEPGPSTNIPENVSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGI

--------------------------------------------------------------
>In-frame_ENST00000240851_ENST00000322875_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(transcript)=2976nt_BP=755nt
GTCCTGGGTATGTCCACGCGCAATAAGGAGGGGCGAAAGGACATTTTTTTTTTTCTTGCTCCCGCCTCTGTTCTTCCCCCACCTGCCACG
TACAGAGCCCAAGTTCTCGCTAGGCTTGTTGGGTCAGCGCGATTGGCCGGGGCCCGCGCGAGCCTGCGAGCGAGGTGCGGCGGTCGCGAA
GGGCAACCGAGGGGGCCGTGACCACCGCCTCCCCGCGACGCCCCAGTCCAGTGGCCTCGCGTCCGCCCATTCAGCGGAGACCTGCGGAGA
GGCGGCGGCCGCGGCCTCCGCAAGCCGTCTTTCTCTAGAGTTGTATATATAGAACATCCTGGAGTCCACCATGAACGGACAGTTGGATCT
AAGTGGGAAGCTAATCATCAAAGCTCAACTTGGGGAGGATATTCGGCGAATTCCTATTCATAATGAAGATATTACTTATGATGAATTAGT
GCTAATGATGCAACGAGTTTTCAGAGGAAAACTTCTGAGTAATGATGAAGTAACAATAAAGTATAAAGATGAAGATGGAGATCTTATAAC
AATTTTTGATAGTTCTGACCTTTCCTTTGCAATTCAGTGCAGTAGGATACTGAAACTGACATTATTTGTTAATGGCCAGCCAAGACCCCT
TGAATCAAGTCAGGTGAAATATCTCCGTCGAGAACTGATAGAACTTCGAAATAAAGTGAATCGTTTATTGGATAGCTTGGAACCACCTGG
AGAACCAGGACCTTCCACCAATATTCCTGAAAATGTGTCGACTTCTTCCACTACAAAATCTCCAGCGTCCAGTGCCTCAGGTCCTAGGCC
TACTTACAAGCCTCCAGTCTCAAATTATCCAGGATATCCTAAACCTGAGGAAGGAATACTTGACAGTTTGGATGTTTGGGTCATTGCTGT
GATTGTTATTGCCATAGTTGTTGGAGTTGCAGTAATTTGTGTTGTCCCGTACAGATATCTTCAAAGGAGGAAGAAGAAAGGGAAAGCAGA
TGGTGGAGCTGAATATGCCACTTACCAGACTAAATCAACCACTCCAGCAGAGCAGAGAGGCTGAATAGATTCCACAACCTGGTTTGCCAG
TTCATCTTTTGACTCTATTAAAATCTTCAATAGTTGTTATTCTGTAGTTTCACTCTCATGAGTGCAACTGTGGCTTAGCTAATATTGCAA
TGTGGCTTGAATGTAGGTAGCATCCTTTGATGCTTCTTTGAAACTTGTATGAATTTGGGTATGAACAGATTGCCTGCTTTCCCTTAAATA
ACACTTAGATTTATTGGACCAGTCAGCACAGCATGCCTGGTTGTATTAAAGCAGGGATATGCTGTATTTTATAAAATTGGCAAAATTAGA
GAAATATAGTTCACAATGAAATTATATTTTCTTTGTAAAGAAAGTGGCTTGAAATCTTTTTTGTTCAAAGATTAATGCCAACTCTTAAGA
TTATTCTTTCACCAACTATAGAATGTATTTTATATATCGTTCATTGTAAAAAGCCCTTAAAAATATGTGTATACTACTTTGGCTCTTGTG
CATAAAAACAAGAACACTGAAAATTGGGAATATGCACAAACTTGGCTTCTTTAACCAAGAATATTATTGGAAAATTCTCTAAAAGTTAAT
AGGGTAAATTCTCTATTTTTTGTAATGTGTTCGGTGATTTCAGAAAGCTAGAAAGTGTATGTGTGGCATTTGTTTTCACTTTTTAAAACA
TCCCTAACTGATCGAATATATCAGTAATTTCAGAATCAGATGCATCCTTTCATAAGAAGTGAGAGGACTCTGACAGCCATAACAGGAGTG
CCACTTCATGGTGCGAAGTGAACACTGTAGTCTTGTTGTTTTCCCAAAGAGAACTCCGTATGTTCTCTTAGGTTGAGTAACCCACTCTGA
ATTCTGGTTACATGTGTTTTTCTCTCCCTCCTTAAATAAAGAGAGGGGTTAAACATGCCCTCTAAAAGTAGGTGGTTTTGAAGAGAATAA
ATTCATCAGATAACCTCAAGTCACATGAGAATCTTAGTCCATTTACATTGCCTTGGCTAGTAAAAGCCATCTATGTATATGTCTTACCTC
ATCTCCTAAAAGGCAGAGTACAAAGTAAGCCATGTATCTCAGGAAGGTAACTTCATTTTGTCTATTTGCTGTTGATTGTACCAAGGGATG
GAAGAAGTAAATATAGCTCAGGTAGCACTTTATACTCAGGCAGATCTCAGCCCTCTACTGAGTCCCTTAGCCAAGCAGTTTCTTTCAAAG
AAGCCAGCAGGCGAAAAGCAGGGACTGCCACTGCATTTCATATCACACTGTTAAAAGTTGTGTTTTGAAATTTTATGTTTAGTTGCACAA
ATTGGGCCAAAGAAACATTGCCTTGAGGAAGATATGATTGGAAAATCAAGAGTGTAGAAGAATAAATACTGTTTTACTGTCCAAAGACAT
GTTTATAGTGCTCTGTAAATGTTCCTTTCCTTTGTAGTCTCTGGCAAGATGCTTTAGGAAGATAAAAGTTTGAGGAGAACAAACAGGAAT
TCTGAATTAAGCACAGAGTTGAAGTTTATACCCGTTTCACATGCTTTTCAAGAATGTCGCAATTACTAAGAAGCAGATAATGGTGTTTTT
TAGAAACCTAATTGAAGTATATTCAACCAAATACTTTAATGTATAAAATAAATATTATACAATATACTTGTATAGCAGTTTCTGCTTCAC
ATTTGATTTTTTCAAATTTAATATTTATATTAGAGATCTATATATGTATAAATATGTATTTTGTCAAATTTGTTACTTAAATATATAGAG
ACCAGTTTTCTCTGGAAGTTTGTTTAAATGACAGAAGCGTATATGAATTCAAGAAAATTTAAGCTGCAAAAATGTATTTGCTATAAAATG
AGAAGTCTCACTGATAGAGGTTCTTTATTGCTCATTTTTTAAAAAATGGACTCTTGAAATCTGTTAAAATAAAATTGTACATTTGGAGAT

>In-frame_ENST00000240851_ENST00000322875_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(amino acids)=241AA_start in transcript=328_stop in transcript=1053
MESTMNGQLDLSGKLIIKAQLGEDIRRIPIHNEDITYDELVLMMQRVFRGKLLSNDEVTIKYKDEDGDLITIFDSSDLSFAIQCSRILKL
TLFVNGQPRPLESSQVKYLRRELIELRNKVNRLLDSLEPPGEPGPSTNIPENVSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGI

--------------------------------------------------------------
>In-frame_ENST00000476228_ENST00000367042_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(transcript)=2888nt_BP=574nt
GGCAACCGAGGGGGCCGTGACCACCGCCTCCCCGCGACGCCCCAGTCCAGTGGCCTCGCGTCCGCCCATTCAGCGGAGACCTGCGGAGAG
GCGGCGGCCGCGGCCTCCGCAAGCCGTCTTTCTCTAGAGTTGTATATATAGAACATCCTGGAGTCCACCATGAACGGACAGTTGGATCTA
AGTGGGAAGCTAATCATCAAAGCTCAACTTGGGGAGGATATTCGGCGAATTCCTATTCATAATGAAGATATTACTTATGATGAATTAGTG
CTAATGATGCAACGAGTTTTCAGAGGAAAACTTCTGAGTAATGATGAAGTAACAATAAAGTATAAAGATGAAGATGGAGATCTTATAACA
ATTTTTGATAGTTCTGACCTTTCCTTTGCAATTCAGTGCAGTAGGATACTGAAACTGACATTATTTGTTAATGGCCAGCCAAGACCCCTT
GAATCAAGTCAGGTGAAATATCTCCGTCGAGAACTGATAGAACTTCGAAATAAAGTGAATCGTTTATTGGATAGCTTGGAACCACCTGGA
GAACCAGGACCTTCCACCAATATTCCTGAAAATGTGTCGACTTCTTCCACTACAAAATCTCCAGCGTCCAGTGCCTCAGGTCCTAGGCCT
ACTTACAAGCCTCCAGTCTCAAATTATCCAGGATATCCTAAACCTGAGGAAGGAATACTTGACAGTTTGGATGTTTGGGTCATTGCTGTG
ATTGTTATTGCCATAGTTGTTGGAGTTGCAGTAATTTGTGTTGTCCCGTACAGATATCTTCAAAGGAGGAAGAAGAAAGGCACATACCTA
ACTGATGAGACCCACAGAGAAGTAAAATTTACTTCTCTCTGAGAAGGAGAGATGAGAGAAAGGTTTGCTTTTATCATTAAAAGGAAAGCA
GATGGTGGAGCTGAATATGCCACTTACCAGACTAAATCAACCACTCCAGCAGAGCAGAGAGGCTGAATAGATTCCACAACCTGGTTTGCC
AGTTCATCTTTTGACTCTATTAAAATCTTCAATAGTTGTTATTCTGTAGTTTCACTCTCATGAGTGCAACTGTGGCTTAGCTAATATTGC
AATGTGGCTTGAATGTAGGTAGCATCCTTTGATGCTTCTTTGAAACTTGTATGAATTTGGGTATGAACAGATTGCCTGCTTTCCCTTAAA
TAACACTTAGATTTATTGGACCAGTCAGCACAGCATGCCTGGTTGTATTAAAGCAGGGATATGCTGTATTTTATAAAATTGGCAAAATTA
GAGAAATATAGTTCACAATGAAATTATATTTTCTTTGTAAAGAAAGTGGCTTGAAATCTTTTTTGTTCAAAGATTAATGCCAACTCTTAA
GATTATTCTTTCACCAACTATAGAATGTATTTTATATATCGTTCATTGTAAAAAGCCCTTAAAAATATGTGTATACTACTTTGGCTCTTG
TGCATAAAAACAAGAACACTGAAAATTGGGAATATGCACAAACTTGGCTTCTTTAACCAAGAATATTATTGGAAAATTCTCTAAAAGTTA
ATAGGGTAAATTCTCTATTTTTTGTAATGTGTTCGGTGATTTCAGAAAGCTAGAAAGTGTATGTGTGGCATTTGTTTTCACTTTTTAAAA
CATCCCTAACTGATCGAATATATCAGTAATTTCAGAATCAGATGCATCCTTTCATAAGAAGTGAGAGGACTCTGACAGCCATAACAGGAG
TGCCACTTCATGGTGCGAAGTGAACACTGTAGTCTTGTTGTTTTCCCAAAGAGAACTCCGTATGTTCTCTTAGGTTGAGTAACCCACTCT
GAATTCTGGTTACATGTGTTTTTCTCTCCCTCCTTAAATAAAGAGAGGGGTTAAACATGCCCTCTAAAAGTAGGTGGTTTTGAAGAGAAT
AAATTCATCAGATAACCTCAAGTCACATGAGAATCTTAGTCCATTTACATTGCCTTGGCTAGTAAAAGCCATCTATGTATATGTCTTACC
TCATCTCCTAAAAGGCAGAGTACAAAGTAAGCCATGTATCTCAGGAAGGTAACTTCATTTTGTCTATTTGCTGTTGATTGTACCAAGGGA
TGGAAGAAGTAAATATAGCTCAGGTAGCACTTTATACTCAGGCAGATCTCAGCCCTCTACTGAGTCCCTTAGCCAAGCAGTTTCTTTCAA
AGAAGCCAGCAGGCGAAAAGCAGGGACTGCCACTGCATTTCATATCACACTGTTAAAAGTTGTGTTTTGAAATTTTATGTTTAGTTGCAC
AAATTGGGCCAAAGAAACATTGCCTTGAGGAAGATATGATTGGAAAATCAAGAGTGTAGAAGAATAAATACTGTTTTACTGTCCAAAGAC
ATGTTTATAGTGCTCTGTAAATGTTCCTTTCCTTTGTAGTCTCTGGCAAGATGCTTTAGGAAGATAAAAGTTTGAGGAGAACAAACAGGA
ATTCTGAATTAAGCACAGAGTTGAAGTTTATACCCGTTTCACATGCTTTTCAAGAATGTCGCAATTACTAAGAAGCAGATAATGGTGTTT
TTTAGAAACCTAATTGAAGTATATTCAACCAAATACTTTAATGTATAAAATAAATATTATACAATATACTTGTATAGCAGTTTCTGCTTC
ACATTTGATTTTTTCAAATTTAATATTTATATTAGAGATCTATATATGTATAAATATGTATTTTGTCAAATTTGTTACTTAAATATATAG
AGACCAGTTTTCTCTGGAAGTTTGTTTAAATGACAGAAGCGTATATGAATTCAAGAAAATTTAAGCTGCAAAAATGTATTTGCTATAAAA
TGAGAAGTCTCACTGATAGAGGTTCTTTATTGCTCATTTTTTAAAAAATGGACTCTTGAAATCTGTTAAAATAAAATTGTACATTTGGAG

>In-frame_ENST00000476228_ENST00000367042_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(amino acids)=234AA_start in transcript=147_stop in transcript=851
MESTMNGQLDLSGKLIIKAQLGEDIRRIPIHNEDITYDELVLMMQRVFRGKLLSNDEVTIKYKDEDGDLITIFDSSDLSFAIQCSRILKL
TLFVNGQPRPLESSQVKYLRRELIELRNKVNRLLDSLEPPGEPGPSTNIPENVSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGI

--------------------------------------------------------------
>In-frame_ENST00000476228_ENST00000354848_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(transcript)=2795nt_BP=574nt
GGCAACCGAGGGGGCCGTGACCACCGCCTCCCCGCGACGCCCCAGTCCAGTGGCCTCGCGTCCGCCCATTCAGCGGAGACCTGCGGAGAG
GCGGCGGCCGCGGCCTCCGCAAGCCGTCTTTCTCTAGAGTTGTATATATAGAACATCCTGGAGTCCACCATGAACGGACAGTTGGATCTA
AGTGGGAAGCTAATCATCAAAGCTCAACTTGGGGAGGATATTCGGCGAATTCCTATTCATAATGAAGATATTACTTATGATGAATTAGTG
CTAATGATGCAACGAGTTTTCAGAGGAAAACTTCTGAGTAATGATGAAGTAACAATAAAGTATAAAGATGAAGATGGAGATCTTATAACA
ATTTTTGATAGTTCTGACCTTTCCTTTGCAATTCAGTGCAGTAGGATACTGAAACTGACATTATTTGTTAATGGCCAGCCAAGACCCCTT
GAATCAAGTCAGGTGAAATATCTCCGTCGAGAACTGATAGAACTTCGAAATAAAGTGAATCGTTTATTGGATAGCTTGGAACCACCTGGA
GAACCAGGACCTTCCACCAATATTCCTGAAAATGTGTCGACTTCTTCCACTACAAAATCTCCAGCGTCCAGTGCCTCAGGTCCTAGGCCT
ACTTACAAGCCTCCAGTCTCAAATTATCCAGGATATCCTAAACCTGAGGAAGGAATACTTGACAGTTTGGATGTTTGGGTCATTGCTGTG
ATTGTTATTGCCATAGTTGTTGGAGTTGCAGTAATTTGTGTTGTCCCGTACAGATATCTTCAAAGGAGGAAGAAGAAAGGGAAAGCAGAT
GGTGGAGCTGAATATGCCACTTACCAGACTAAATCAACCACTCCAGCAGAGCAGAGAGGCTGAATAGATTCCACAACCTGGTTTGCCAGT
TCATCTTTTGACTCTATTAAAATCTTCAATAGTTGTTATTCTGTAGTTTCACTCTCATGAGTGCAACTGTGGCTTAGCTAATATTGCAAT
GTGGCTTGAATGTAGGTAGCATCCTTTGATGCTTCTTTGAAACTTGTATGAATTTGGGTATGAACAGATTGCCTGCTTTCCCTTAAATAA
CACTTAGATTTATTGGACCAGTCAGCACAGCATGCCTGGTTGTATTAAAGCAGGGATATGCTGTATTTTATAAAATTGGCAAAATTAGAG
AAATATAGTTCACAATGAAATTATATTTTCTTTGTAAAGAAAGTGGCTTGAAATCTTTTTTGTTCAAAGATTAATGCCAACTCTTAAGAT
TATTCTTTCACCAACTATAGAATGTATTTTATATATCGTTCATTGTAAAAAGCCCTTAAAAATATGTGTATACTACTTTGGCTCTTGTGC
ATAAAAACAAGAACACTGAAAATTGGGAATATGCACAAACTTGGCTTCTTTAACCAAGAATATTATTGGAAAATTCTCTAAAAGTTAATA
GGGTAAATTCTCTATTTTTTGTAATGTGTTCGGTGATTTCAGAAAGCTAGAAAGTGTATGTGTGGCATTTGTTTTCACTTTTTAAAACAT
CCCTAACTGATCGAATATATCAGTAATTTCAGAATCAGATGCATCCTTTCATAAGAAGTGAGAGGACTCTGACAGCCATAACAGGAGTGC
CACTTCATGGTGCGAAGTGAACACTGTAGTCTTGTTGTTTTCCCAAAGAGAACTCCGTATGTTCTCTTAGGTTGAGTAACCCACTCTGAA
TTCTGGTTACATGTGTTTTTCTCTCCCTCCTTAAATAAAGAGAGGGGTTAAACATGCCCTCTAAAAGTAGGTGGTTTTGAAGAGAATAAA
TTCATCAGATAACCTCAAGTCACATGAGAATCTTAGTCCATTTACATTGCCTTGGCTAGTAAAAGCCATCTATGTATATGTCTTACCTCA
TCTCCTAAAAGGCAGAGTACAAAGTAAGCCATGTATCTCAGGAAGGTAACTTCATTTTGTCTATTTGCTGTTGATTGTACCAAGGGATGG
AAGAAGTAAATATAGCTCAGGTAGCACTTTATACTCAGGCAGATCTCAGCCCTCTACTGAGTCCCTTAGCCAAGCAGTTTCTTTCAAAGA
AGCCAGCAGGCGAAAAGCAGGGACTGCCACTGCATTTCATATCACACTGTTAAAAGTTGTGTTTTGAAATTTTATGTTTAGTTGCACAAA
TTGGGCCAAAGAAACATTGCCTTGAGGAAGATATGATTGGAAAATCAAGAGTGTAGAAGAATAAATACTGTTTTACTGTCCAAAGACATG
TTTATAGTGCTCTGTAAATGTTCCTTTCCTTTGTAGTCTCTGGCAAGATGCTTTAGGAAGATAAAAGTTTGAGGAGAACAAACAGGAATT
CTGAATTAAGCACAGAGTTGAAGTTTATACCCGTTTCACATGCTTTTCAAGAATGTCGCAATTACTAAGAAGCAGATAATGGTGTTTTTT
AGAAACCTAATTGAAGTATATTCAACCAAATACTTTAATGTATAAAATAAATATTATACAATATACTTGTATAGCAGTTTCTGCTTCACA
TTTGATTTTTTCAAATTTAATATTTATATTAGAGATCTATATATGTATAAATATGTATTTTGTCAAATTTGTTACTTAAATATATAGAGA
CCAGTTTTCTCTGGAAGTTTGTTTAAATGACAGAAGCGTATATGAATTCAAGAAAATTTAAGCTGCAAAAATGTATTTGCTATAAAATGA
GAAGTCTCACTGATAGAGGTTCTTTATTGCTCATTTTTTAAAAAATGGACTCTTGAAATCTGTTAAAATAAAATTGTACATTTGGAGATG

>In-frame_ENST00000476228_ENST00000354848_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(amino acids)=241AA_start in transcript=147_stop in transcript=872
MESTMNGQLDLSGKLIIKAQLGEDIRRIPIHNEDITYDELVLMMQRVFRGKLLSNDEVTIKYKDEDGDLITIFDSSDLSFAIQCSRILKL
TLFVNGQPRPLESSQVKYLRRELIELRNKVNRLLDSLEPPGEPGPSTNIPENVSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGI

--------------------------------------------------------------
>In-frame_ENST00000476228_ENST00000441839_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(transcript)=2731nt_BP=574nt
GGCAACCGAGGGGGCCGTGACCACCGCCTCCCCGCGACGCCCCAGTCCAGTGGCCTCGCGTCCGCCCATTCAGCGGAGACCTGCGGAGAG
GCGGCGGCCGCGGCCTCCGCAAGCCGTCTTTCTCTAGAGTTGTATATATAGAACATCCTGGAGTCCACCATGAACGGACAGTTGGATCTA
AGTGGGAAGCTAATCATCAAAGCTCAACTTGGGGAGGATATTCGGCGAATTCCTATTCATAATGAAGATATTACTTATGATGAATTAGTG
CTAATGATGCAACGAGTTTTCAGAGGAAAACTTCTGAGTAATGATGAAGTAACAATAAAGTATAAAGATGAAGATGGAGATCTTATAACA
ATTTTTGATAGTTCTGACCTTTCCTTTGCAATTCAGTGCAGTAGGATACTGAAACTGACATTATTTGTTAATGGCCAGCCAAGACCCCTT
GAATCAAGTCAGGTGAAATATCTCCGTCGAGAACTGATAGAACTTCGAAATAAAGTGAATCGTTTATTGGATAGCTTGGAACCACCTGGA
GAACCAGGACCTTCCACCAATATTCCTGAAAATGTGTCGACTTCTTCCACTACAAAATCTCCAGCGTCCAGTGCCTCAGGTCCTAGGCCT
ACTTACAAGCCTCCAGTCTCAAATTATCCAGGATATCCTAAACCTGAGGAAGGAATACTTGACAGTTTGGATGTTTGGGTCATTGCTGTG
ATTGTTATTGCCATAGGAAAGCAGATGGTGGAGCTGAATATGCCACTTACCAGACTAAATCAACCACTCCAGCAGAGCAGAGAGGCTGAA
TAGATTCCACAACCTGGTTTGCCAGTTCATCTTTTGACTCTATTAAAATCTTCAATAGTTGTTATTCTGTAGTTTCACTCTCATGAGTGC
AACTGTGGCTTAGCTAATATTGCAATGTGGCTTGAATGTAGGTAGCATCCTTTGATGCTTCTTTGAAACTTGTATGAATTTGGGTATGAA
CAGATTGCCTGCTTTCCCTTAAATAACACTTAGATTTATTGGACCAGTCAGCACAGCATGCCTGGTTGTATTAAAGCAGGGATATGCTGT
ATTTTATAAAATTGGCAAAATTAGAGAAATATAGTTCACAATGAAATTATATTTTCTTTGTAAAGAAAGTGGCTTGAAATCTTTTTTGTT
CAAAGATTAATGCCAACTCTTAAGATTATTCTTTCACCAACTATAGAATGTATTTTATATATCGTTCATTGTAAAAAGCCCTTAAAAATA
TGTGTATACTACTTTGGCTCTTGTGCATAAAAACAAGAACACTGAAAATTGGGAATATGCACAAACTTGGCTTCTTTAACCAAGAATATT
ATTGGAAAATTCTCTAAAAGTTAATAGGGTAAATTCTCTATTTTTTGTAATGTGTTCGGTGATTTCAGAAAGCTAGAAAGTGTATGTGTG
GCATTTGTTTTCACTTTTTAAAACATCCCTAACTGATCGAATATATCAGTAATTTCAGAATCAGATGCATCCTTTCATAAGAAGTGAGAG
GACTCTGACAGCCATAACAGGAGTGCCACTTCATGGTGCGAAGTGAACACTGTAGTCTTGTTGTTTTCCCAAAGAGAACTCCGTATGTTC
TCTTAGGTTGAGTAACCCACTCTGAATTCTGGTTACATGTGTTTTTCTCTCCCTCCTTAAATAAAGAGAGGGGTTAAACATGCCCTCTAA
AAGTAGGTGGTTTTGAAGAGAATAAATTCATCAGATAACCTCAAGTCACATGAGAATCTTAGTCCATTTACATTGCCTTGGCTAGTAAAA
GCCATCTATGTATATGTCTTACCTCATCTCCTAAAAGGCAGAGTACAAAGTAAGCCATGTATCTCAGGAAGGTAACTTCATTTTGTCTAT
TTGCTGTTGATTGTACCAAGGGATGGAAGAAGTAAATATAGCTCAGGTAGCACTTTATACTCAGGCAGATCTCAGCCCTCTACTGAGTCC
CTTAGCCAAGCAGTTTCTTTCAAAGAAGCCAGCAGGCGAAAAGCAGGGACTGCCACTGCATTTCATATCACACTGTTAAAAGTTGTGTTT
TGAAATTTTATGTTTAGTTGCACAAATTGGGCCAAAGAAACATTGCCTTGAGGAAGATATGATTGGAAAATCAAGAGTGTAGAAGAATAA
ATACTGTTTTACTGTCCAAAGACATGTTTATAGTGCTCTGTAAATGTTCCTTTCCTTTGTAGTCTCTGGCAAGATGCTTTAGGAAGATAA
AAGTTTGAGGAGAACAAACAGGAATTCTGAATTAAGCACAGAGTTGAAGTTTATACCCGTTTCACATGCTTTTCAAGAATGTCGCAATTA
CTAAGAAGCAGATAATGGTGTTTTTTAGAAACCTAATTGAAGTATATTCAACCAAATACTTTAATGTATAAAATAAATATTATACAATAT
ACTTGTATAGCAGTTTCTGCTTCACATTTGATTTTTTCAAATTTAATATTTATATTAGAGATCTATATATGTATAAATATGTATTTTGTC
AAATTTGTTACTTAAATATATAGAGACCAGTTTTCTCTGGAAGTTTGTTTAAATGACAGAAGCGTATATGAATTCAAGAAAATTTAAGCT
GCAAAAATGTATTTGCTATAAAATGAGAAGTCTCACTGATAGAGGTTCTTTATTGCTCATTTTTTAAAAAATGGACTCTTGAAATCTGTT

>In-frame_ENST00000476228_ENST00000441839_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(amino acids)=221AA_start in transcript=147_stop in transcript=812
MESTMNGQLDLSGKLIIKAQLGEDIRRIPIHNEDITYDELVLMMQRVFRGKLLSNDEVTIKYKDEDGDLITIFDSSDLSFAIQCSRILKL
TLFVNGQPRPLESSQVKYLRRELIELRNKVNRLLDSLEPPGEPGPSTNIPENVSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGI

--------------------------------------------------------------
>In-frame_ENST00000476228_ENST00000322875_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(transcript)=2795nt_BP=574nt
GGCAACCGAGGGGGCCGTGACCACCGCCTCCCCGCGACGCCCCAGTCCAGTGGCCTCGCGTCCGCCCATTCAGCGGAGACCTGCGGAGAG
GCGGCGGCCGCGGCCTCCGCAAGCCGTCTTTCTCTAGAGTTGTATATATAGAACATCCTGGAGTCCACCATGAACGGACAGTTGGATCTA
AGTGGGAAGCTAATCATCAAAGCTCAACTTGGGGAGGATATTCGGCGAATTCCTATTCATAATGAAGATATTACTTATGATGAATTAGTG
CTAATGATGCAACGAGTTTTCAGAGGAAAACTTCTGAGTAATGATGAAGTAACAATAAAGTATAAAGATGAAGATGGAGATCTTATAACA
ATTTTTGATAGTTCTGACCTTTCCTTTGCAATTCAGTGCAGTAGGATACTGAAACTGACATTATTTGTTAATGGCCAGCCAAGACCCCTT
GAATCAAGTCAGGTGAAATATCTCCGTCGAGAACTGATAGAACTTCGAAATAAAGTGAATCGTTTATTGGATAGCTTGGAACCACCTGGA
GAACCAGGACCTTCCACCAATATTCCTGAAAATGTGTCGACTTCTTCCACTACAAAATCTCCAGCGTCCAGTGCCTCAGGTCCTAGGCCT
ACTTACAAGCCTCCAGTCTCAAATTATCCAGGATATCCTAAACCTGAGGAAGGAATACTTGACAGTTTGGATGTTTGGGTCATTGCTGTG
ATTGTTATTGCCATAGTTGTTGGAGTTGCAGTAATTTGTGTTGTCCCGTACAGATATCTTCAAAGGAGGAAGAAGAAAGGGAAAGCAGAT
GGTGGAGCTGAATATGCCACTTACCAGACTAAATCAACCACTCCAGCAGAGCAGAGAGGCTGAATAGATTCCACAACCTGGTTTGCCAGT
TCATCTTTTGACTCTATTAAAATCTTCAATAGTTGTTATTCTGTAGTTTCACTCTCATGAGTGCAACTGTGGCTTAGCTAATATTGCAAT
GTGGCTTGAATGTAGGTAGCATCCTTTGATGCTTCTTTGAAACTTGTATGAATTTGGGTATGAACAGATTGCCTGCTTTCCCTTAAATAA
CACTTAGATTTATTGGACCAGTCAGCACAGCATGCCTGGTTGTATTAAAGCAGGGATATGCTGTATTTTATAAAATTGGCAAAATTAGAG
AAATATAGTTCACAATGAAATTATATTTTCTTTGTAAAGAAAGTGGCTTGAAATCTTTTTTGTTCAAAGATTAATGCCAACTCTTAAGAT
TATTCTTTCACCAACTATAGAATGTATTTTATATATCGTTCATTGTAAAAAGCCCTTAAAAATATGTGTATACTACTTTGGCTCTTGTGC
ATAAAAACAAGAACACTGAAAATTGGGAATATGCACAAACTTGGCTTCTTTAACCAAGAATATTATTGGAAAATTCTCTAAAAGTTAATA
GGGTAAATTCTCTATTTTTTGTAATGTGTTCGGTGATTTCAGAAAGCTAGAAAGTGTATGTGTGGCATTTGTTTTCACTTTTTAAAACAT
CCCTAACTGATCGAATATATCAGTAATTTCAGAATCAGATGCATCCTTTCATAAGAAGTGAGAGGACTCTGACAGCCATAACAGGAGTGC
CACTTCATGGTGCGAAGTGAACACTGTAGTCTTGTTGTTTTCCCAAAGAGAACTCCGTATGTTCTCTTAGGTTGAGTAACCCACTCTGAA
TTCTGGTTACATGTGTTTTTCTCTCCCTCCTTAAATAAAGAGAGGGGTTAAACATGCCCTCTAAAAGTAGGTGGTTTTGAAGAGAATAAA
TTCATCAGATAACCTCAAGTCACATGAGAATCTTAGTCCATTTACATTGCCTTGGCTAGTAAAAGCCATCTATGTATATGTCTTACCTCA
TCTCCTAAAAGGCAGAGTACAAAGTAAGCCATGTATCTCAGGAAGGTAACTTCATTTTGTCTATTTGCTGTTGATTGTACCAAGGGATGG
AAGAAGTAAATATAGCTCAGGTAGCACTTTATACTCAGGCAGATCTCAGCCCTCTACTGAGTCCCTTAGCCAAGCAGTTTCTTTCAAAGA
AGCCAGCAGGCGAAAAGCAGGGACTGCCACTGCATTTCATATCACACTGTTAAAAGTTGTGTTTTGAAATTTTATGTTTAGTTGCACAAA
TTGGGCCAAAGAAACATTGCCTTGAGGAAGATATGATTGGAAAATCAAGAGTGTAGAAGAATAAATACTGTTTTACTGTCCAAAGACATG
TTTATAGTGCTCTGTAAATGTTCCTTTCCTTTGTAGTCTCTGGCAAGATGCTTTAGGAAGATAAAAGTTTGAGGAGAACAAACAGGAATT
CTGAATTAAGCACAGAGTTGAAGTTTATACCCGTTTCACATGCTTTTCAAGAATGTCGCAATTACTAAGAAGCAGATAATGGTGTTTTTT
AGAAACCTAATTGAAGTATATTCAACCAAATACTTTAATGTATAAAATAAATATTATACAATATACTTGTATAGCAGTTTCTGCTTCACA
TTTGATTTTTTCAAATTTAATATTTATATTAGAGATCTATATATGTATAAATATGTATTTTGTCAAATTTGTTACTTAAATATATAGAGA
CCAGTTTTCTCTGGAAGTTTGTTTAAATGACAGAAGCGTATATGAATTCAAGAAAATTTAAGCTGCAAAAATGTATTTGCTATAAAATGA
GAAGTCTCACTGATAGAGGTTCTTTATTGCTCATTTTTTAAAAAATGGACTCTTGAAATCTGTTAAAATAAAATTGTACATTTGGAGATG

>In-frame_ENST00000476228_ENST00000322875_TCGA-66-2787-01A_TFG_chr3_100447702_+_CD46_chr1_207941124_length(amino acids)=241AA_start in transcript=147_stop in transcript=872
MESTMNGQLDLSGKLIIKAQLGEDIRRIPIHNEDITYDELVLMMQRVFRGKLLSNDEVTIKYKDEDGDLITIFDSSDLSFAIQCSRILKL
TLFVNGQPRPLESSQVKYLRRELIELRNKVNRLLDSLEPPGEPGPSTNIPENVSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGI

--------------------------------------------------------------

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Fusion Gene PPI Analysis for TFG-CD46


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TFG-CD46


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TFG-CD46


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneTFGC3714897SPASTIC PARAPLEGIA 57, AUTOSOMAL RECESSIVE5CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
HgeneTFGC1858338Neuropathy, hereditary motor and sensory, Okinawa type4CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
HgeneTFGC0238463Papillary thyroid carcinoma2ORPHANET
HgeneTFGC0442874Neuropathy1GENOMICS_ENGLAND
HgeneTFGC1275278Extraskeletal Myxoid Chondrosarcoma1GENOMICS_ENGLAND;ORPHANET
HgeneTFGC3714756Intellectual Disability1GENOMICS_ENGLAND
TgeneCD46C2752040HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 26GENOMICS_ENGLAND;UNIPROT
TgeneCD46C2931788Atypical Hemolytic Uremic Syndrome2CTD_human;GENOMICS_ENGLAND
TgeneCD46C0019061Hemolytic-Uremic Syndrome1GENOMICS_ENGLAND
TgeneCD46C0025007Measles1CTD_human
TgeneCD46C0162739HELLP Syndrome1ORPHANET
TgeneCD46C0272242Complement deficiency disease1GENOMICS_ENGLAND
TgeneCD46C3658266Prostatic Cancer, Castration-Resistant1CTD_human
TgeneCD46C3658267Prostatic Neoplasms, Castration-Resistant1CTD_human
TgeneCD46C4087273C3 glomerulopathy1GENOMICS_ENGLAND