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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:BANK1-AGMO (FusionGDB2 ID:9026)

Fusion Gene Summary for BANK1-AGMO

check button Fusion gene summary
Fusion gene informationFusion gene name: BANK1-AGMO
Fusion gene ID: 9026
HgeneTgene
Gene symbol

BANK1

AGMO

Gene ID

55024

392636

Gene nameB cell scaffold protein with ankyrin repeats 1alkylglycerol monooxygenase
SynonymsBANKTMEM195
Cytomap

4q24

7p21.2

Type of geneprotein-codingprotein-coding
DescriptionB-cell scaffold protein with ankyrin repeatsalkylglycerol monooxygenaseglyceryl-ether monooxygenasetransmembrane protein 195
Modification date2020031320200313
UniProtAcc.

Q6ZNB7

Ensembl transtripts involved in fusion geneENST00000504592, ENST00000322953, 
ENST00000428908, ENST00000508653, 
ENST00000444316, ENST00000510950, 
ENST00000342526, ENST00000498264, 
Fusion gene scores* DoF score5 X 5 X 2=506 X 5 X 4=120
# samples 77
** MAII scorelog2(7/50*10)=0.485426827170242
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(7/120*10)=-0.777607578663552
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: BANK1 [Title/Abstract] AND AGMO [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointBANK1(102965064)-AGMO(15240984), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneBANK1

GO:0042113

B cell activation

11782428

TgeneAGMO

GO:0006643

membrane lipid metabolic process

20643956

TgeneAGMO

GO:0046485

ether lipid metabolic process

20643956


check buttonFusion gene breakpoints across BANK1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across AGMO (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-HC-A6AL-01ABANK1chr4

102965064

+AGMOchr7

15240984

-
ChimerDB4PRADTCGA-HC-A6ALBANK1chr4

102965064

+AGMOchr7

15240984

-
ChimerDB4PRADTCGA-HC-A6AL-01ABANK1chr4

102965064

-AGMOchr7

15240984

-


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Fusion Gene ORF analysis for BANK1-AGMO

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000504592ENST00000342526BANK1chr4

102965064

+AGMOchr7

15240984

-
5CDS-intronENST00000504592ENST00000498264BANK1chr4

102965064

+AGMOchr7

15240984

-
In-frameENST00000322953ENST00000342526BANK1chr4

102965064

+AGMOchr7

15240984

-
5CDS-intronENST00000322953ENST00000498264BANK1chr4

102965064

+AGMOchr7

15240984

-
In-frameENST00000428908ENST00000342526BANK1chr4

102965064

+AGMOchr7

15240984

-
5CDS-intronENST00000428908ENST00000498264BANK1chr4

102965064

+AGMOchr7

15240984

-
In-frameENST00000508653ENST00000342526BANK1chr4

102965064

+AGMOchr7

15240984

-
5CDS-intronENST00000508653ENST00000498264BANK1chr4

102965064

+AGMOchr7

15240984

-
In-frameENST00000444316ENST00000342526BANK1chr4

102965064

+AGMOchr7

15240984

-
5CDS-intronENST00000444316ENST00000498264BANK1chr4

102965064

+AGMOchr7

15240984

-
intron-3CDSENST00000510950ENST00000342526BANK1chr4

102965064

+AGMOchr7

15240984

-
intron-intronENST00000510950ENST00000498264BANK1chr4

102965064

+AGMOchr7

15240984

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000504592BANK1chr4102965064+ENST00000342526AGMOchr715240984-338423424182379653
ENST00000322953BANK1chr4102965064+ENST00000342526AGMOchr715240984-328522431122280722
ENST00000428908BANK1chr4102965064+ENST00000342526AGMOchr715240984-288618441121881589
ENST00000508653BANK1chr4102965064+ENST00000342526AGMOchr715240984-27631721821758558
ENST00000444316BANK1chr4102965064+ENST00000342526AGMOchr715240984-305420121332049638

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000504592ENST00000342526BANK1chr4102965064+AGMOchr715240984-0.0013078730.9986921
ENST00000322953ENST00000342526BANK1chr4102965064+AGMOchr715240984-0.0005221610.9994779
ENST00000428908ENST00000342526BANK1chr4102965064+AGMOchr715240984-0.0007467780.9992532
ENST00000508653ENST00000342526BANK1chr4102965064+AGMOchr715240984-0.0006397050.99936026
ENST00000444316ENST00000342526BANK1chr4102965064+AGMOchr715240984-0.0007385910.99926144

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Fusion Genomic Features for BANK1-AGMO


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for BANK1-AGMO


check button Go to

FGviewer for the breakpoints of chr4:102965064-chr7:15240984

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.AGMO

Q6ZNB7

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids. Ether lipids are essential components of brain membranes. {ECO:0000269|PubMed:20643956}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBANK1chr4:102965064chr7:15240984ENST00000322953+1117200_327656.3333333333334916.3333333333334DomainDBB
HgeneBANK1chr4:102965064chr7:15240984ENST00000322953+111725_153656.3333333333334916.3333333333334DomainTIR
HgeneBANK1chr4:102965064chr7:15240984ENST00000428908+1016200_327523.3333333333334807.0DomainDBB
HgeneBANK1chr4:102965064chr7:15240984ENST00000428908+101625_153523.3333333333334807.0DomainTIR
HgeneBANK1chr4:102965064chr7:15240984ENST00000444316+1117200_327626.3333333333334963.3333333333334DomainDBB
HgeneBANK1chr4:102965064chr7:15240984ENST00000444316+111725_153626.3333333333334963.3333333333334DomainTIR
HgeneBANK1chr4:102965064chr7:15240984ENST00000504592+1521200_327641.3333333333334994.6666666666666DomainDBB
HgeneBANK1chr4:102965064chr7:15240984ENST00000504592+152125_153641.3333333333334994.6666666666666DomainTIR
HgeneBANK1chr4:102965064chr7:15240984ENST00000508653+1015200_327523.3333333333334653.0DomainDBB
HgeneBANK1chr4:102965064chr7:15240984ENST00000508653+101525_153523.3333333333334653.0DomainTIR
HgeneBANK1chr4:102965064chr7:15240984ENST00000322953+1117342_371656.3333333333334916.3333333333334RepeatNote=ANK 1
HgeneBANK1chr4:102965064chr7:15240984ENST00000322953+1117378_408656.3333333333334916.3333333333334RepeatNote=ANK 2
HgeneBANK1chr4:102965064chr7:15240984ENST00000428908+1016342_371523.3333333333334807.0RepeatNote=ANK 1
HgeneBANK1chr4:102965064chr7:15240984ENST00000428908+1016378_408523.3333333333334807.0RepeatNote=ANK 2
HgeneBANK1chr4:102965064chr7:15240984ENST00000444316+1117342_371626.3333333333334963.3333333333334RepeatNote=ANK 1
HgeneBANK1chr4:102965064chr7:15240984ENST00000444316+1117378_408626.3333333333334963.3333333333334RepeatNote=ANK 2
HgeneBANK1chr4:102965064chr7:15240984ENST00000504592+1521342_371641.3333333333334994.6666666666666RepeatNote=ANK 1
HgeneBANK1chr4:102965064chr7:15240984ENST00000504592+1521378_408641.3333333333334994.6666666666666RepeatNote=ANK 2
HgeneBANK1chr4:102965064chr7:15240984ENST00000508653+1015342_371523.3333333333334653.0RepeatNote=ANK 1
HgeneBANK1chr4:102965064chr7:15240984ENST00000508653+1015378_408523.3333333333334653.0RepeatNote=ANK 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneAGMOchr4:102965064chr7:15240984ENST000003425261113120_249421.0446.0DomainFatty acid hydroxylase
TgeneAGMOchr4:102965064chr7:15240984ENST000003425261113132_136421.0446.0MotifNote=Histidine box-1
TgeneAGMOchr4:102965064chr7:15240984ENST000003425261113145_149421.0446.0MotifNote=Histidine box-2
TgeneAGMOchr4:102965064chr7:15240984ENST000003425261113221_225421.0446.0MotifNote=Histidine box-3
TgeneAGMOchr4:102965064chr7:15240984ENST000003425261113111_131421.0446.0TransmembraneHelical
TgeneAGMOchr4:102965064chr7:15240984ENST000003425261113334_354421.0446.0TransmembraneHelical
TgeneAGMOchr4:102965064chr7:15240984ENST000003425261113363_383421.0446.0TransmembraneHelical
TgeneAGMOchr4:102965064chr7:15240984ENST000003425261113413_433421.0446.0TransmembraneHelical
TgeneAGMOchr4:102965064chr7:15240984ENST00000342526111343_63421.0446.0TransmembraneHelical


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Fusion Gene Sequence for BANK1-AGMO


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000504592_ENST00000342526_TCGA-HC-A6AL-01A_BANK1_chr4_102965064_+_AGMO_chr7_15240984_length(transcript)=3384nt_BP=2342nt
TTTGGTTTCTCTTCAAGAATTAACAAACCACTTACTCTTGAATTCTCTTCTAGTTAACACAGGCATCACTACTTCCAATTGATCTCAGGA
TGTGGGATCCTCATACACATTTTGAACAAAATCCTCTGTTTCAGCAAGGAATTCATATTTGCATATGGTGAAGATGGTTTCTGAAGTGAG
ATCAGAAGTAGAGCTTCTAATGACCCCCAGAAGCACTGAGTGACCAAGTGACATACCTGCCAGGCCCATTGTGTCCATCGCTCTCAGAGC
AGCTGGGGATTGTGCTTGGCTCCCAGAGCTATGGTGCAAAAGGCGGGGTCGCTAGGGCCACTCAGGGAAAGAGAACCCAGAAACATGGCA
TGCTGACAAAAGGTAGTCTCTGCTTATCCAGCTTCACTTTCTGCTGATTTAGTTACCCATGGTCAACTGCCATCTGAAAATAGGAAATAC
AAAAGATATAATAATGATATATGAAGAAGATGCTGAGGAATGGGCTCTGTACTTGACAGAAGTATTTTTACATGTTGTGAAAAGGGAAGC
CATCCTGTTATATCGCTTGGAGAATTTCTCTTTTCGGCATTTGGAGTTGCTGAACTTAACGTCTTACAAATGTAAACTTTTGATATTATC
AAATAGCCTGCTTAGAGACCTAACTCCAAAGAAATGTCAGTTTCTGGAAAAGATACTTCATTCACCAAAAAGTGTAGTTACTTTGCTTTG
TGGAGTGAAGAGTTCAGATCAGCTCTATGAATTACTAAATATCTCTCAAAGCAGATGGGAGATCTCAACTGAACAGGAACCTGAAGACTA
CATCTCTGTAATCCAGAGTATCATATTCAAAGATTCTGAAGACTACTTTGAGGTCAACATTCCAACAGACCTACGAGCAAAACATTCTGG
GGAAATAAGTGAGAGAAAGGAAATTGAAGAACTATCAGAAGCTTCAAGAAACACCATACCACTAGCAGTGGTGCTTCCCACTGAAATTCC
ATGTGAGAATCCTGGTGAAATATTCATAATTTTGAGAGATGAAGTAATTGGTGATACTGTAGAGGTTGAATTTACATCAAGTAATAAGCG
CATTAGAACACGGCCAGCCCTTTGGAATAAGAAAGTCTGGTGCATGAAAGCTTTAGAGTTTCCTGCTGGTTCAGTCCATGTCAATGTCTA
CTGTGATGGAATCGTTAAAGCTACAACCAAAATTAAGTACTACCCAACAGCAAAGGCAAAGGAATGCCTATTCAGAATGGCAGATTCAGG
AGAGAGTTTGTGCCAGAATAGCATTGAAGAACTTGATGGTGTCCTTACATCCATATTCAAACATGAGATACCATATTATGAGTTCCAGTC
TCTTCAAACTGAAATTTGTTCTCAAAACAAATATACTCATTTCAAAGAACTTCCAACTCTTCTCCACTGTGCAGCAAAATTTGGCTTAAA
GAACCTGGCTATTCATTTGCTTCAATGTTCAGGAGCAACCTGGGCATCTAAGATGAAAAATATGGAGGGTTCAGACCCCGCACATATTGC
TGAAAGGCATGGTCACAAAGAACTCAAGAAAATCTTCGAAGACTTTTCAATCCAAGAAATTGACATAAATAATGAGCAAGAAAATGATTA
TGAAGAGGATATTGCCTCATTTTCCACATATATTCCTTCCACACAGAACCCAGCATTTCATCATGAAAGCAGGAAGACATACGGGCAGAG
TGCAGATGGAGCTGAGGCAAATGAAATGGAAGGGGAAGGAAAACAGAATGGATCAGGCATGGAGACCAAACACAGCCCACTAGAGGTTGG
CAGTGAGAGTTCTGAAGACCAGTATGATGACTTGTATGTGTTCATTCCTGGTGCTGATCCAGAAAATAATTCACAAGAGCCACTCATGAG
CAGCAGACCTCCTCTCCCCCCGCCGCGACCTGTAGCTAATGCCTTCCAACTGGAAAGACCTCACTTCACCTTACCAGGGACAATGGTGGA
AGGCCAAATGGAAAGAAGTCAAAACTGGGGTCATCCTGGTGTTAGACAAGAAACAGGAGATGAACCCAAAGGAGAAAAAGAGAAGAAAGA
AGAGGAAAAAGAGCAGGAGGAGGAAGAAGACCCATATACTTTTGCTGAGATTGATGACAGTGAATATGACATGATATTGGCCAATCTGAG
TATAAAGAAAAAAACTGGGAGTCGGTCTTTCATTATAAATAGACCTCCTGCCCCCACACCCCGACCCACAAGTATACCTCCAAAAGAGGA
AACTACACCTTACATAGCTCAAGTGTTTCAACAAAAGACAGCCAGAAGACAATCTGATGATGACAAGTTCTGTGGTCTTCCTAAGAAACA
AGATTGTTTTTTCCATTTGCATTGCTTTCTGGGGAGTTAGAAGCATGAAACAACTCACCTCTCACCCTTGGAAATAACCTGAATTTGTAC
ATAATTCTCTTCTTTTAATGAGTTGTCCACACGCATATTATGACTGCATATTAAAATGTAATTATTTTATGTAATGCTTATATGAACTAT
TTCTTCAATGAAAAGTAAAATTACTTATTTACTATTGTTTGCCTTTCACATTTGTTATTTTCTATTAAAAATTAAAGTCAGTTTTGGTTA
CTTCCCCCCTTTACTACAATTAAAAAAAGATTTCAAATATAATGATGTTATATTAACTGATAGCCTTATATGACAAGTATAAAAAGAAGG
GATGAAACTTAAAAACAGTAAAAACAAGAAGGAATATTGCCTTTACATCAATTTGAAAACAATGTTTCCTTTGATGTTTGCTAAAATTAT
GCATAGATACATGTTTGTAGTCATAAAAATGTATTACATTGGTTGTCTTCCTAAGGCCACAGTTACCTTTGCAATCCATATAACCTAAGA
AGCTGCATTCCAGAAAAAGACATCACTGAGGCCAGGCGCGGTGGCTCACCCCTGTAATCCCAGCACTTTGTGGGGCTGAGGTGGGCGGAT
CATGAGGTCCAGAGATAGAGACCATCCTGGCCAACATGGTGAAGTCCTGTCTCTACTAAAAATATAAAAATTTAGCTGGACATGGTGGTG
TGCGCCTGTAGTCCCAGCTACTCTGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGCAGAAGTTGGAGTGAGTGGAGATTGCACC
ACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCCGTCTCAAAGAAAAAAGACATCACTGAAAGAAAAATGAACAGAATTTGTCAGAATT
AGTTTTTTCAACAGGTTACTTTGTCATACATTTCTCTAATATGCTTGGTCAATTTGTTTTGGCAGACTGGGCAGCATGCAGCAATTCTGC

>In-frame_ENST00000504592_ENST00000342526_TCGA-HC-A6AL-01A_BANK1_chr4_102965064_+_AGMO_chr7_15240984_length(amino acids)=653AA_start in transcript=418_stop in transcript=2379
MVNCHLKIGNTKDIIMIYEEDAEEWALYLTEVFLHVVKREAILLYRLENFSFRHLELLNLTSYKCKLLILSNSLLRDLTPKKCQFLEKIL
HSPKSVVTLLCGVKSSDQLYELLNISQSRWEISTEQEPEDYISVIQSIIFKDSEDYFEVNIPTDLRAKHSGEISERKEIEELSEASRNTI
PLAVVLPTEIPCENPGEIFIILRDEVIGDTVEVEFTSSNKRIRTRPALWNKKVWCMKALEFPAGSVHVNVYCDGIVKATTKIKYYPTAKA
KECLFRMADSGESLCQNSIEELDGVLTSIFKHEIPYYEFQSLQTEICSQNKYTHFKELPTLLHCAAKFGLKNLAIHLLQCSGATWASKMK
NMEGSDPAHIAERHGHKELKKIFEDFSIQEIDINNEQENDYEEDIASFSTYIPSTQNPAFHHESRKTYGQSADGAEANEMEGEGKQNGSG
METKHSPLEVGSESSEDQYDDLYVFIPGADPENNSQEPLMSSRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGVRQETG
DEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSEYDMILANLSIKKKTGSRSFIINRPPAPTPRPTSIPPKEETTPYIAQVFQQKTARRQSD

--------------------------------------------------------------
>In-frame_ENST00000322953_ENST00000342526_TCGA-HC-A6AL-01A_BANK1_chr4_102965064_+_AGMO_chr7_15240984_length(transcript)=3285nt_BP=2243nt
AAACCAAAGCGGCCTTTTGAGAAGGGATGTAAGAGCAGGCCCCTGAGCAGTTTCACTTCCTCTGGGCGCCCAGCAGAGCGGAGCCCTGGC
CTTGCGGGCATGAGCCCCGGGGCTGCGTTTCCTGAGACCTGGCCGCAGCCTCCGCGGGTGGCAAGCGGGCTGGGGAGAGCCGAGGGCCAA
AGGAAGAGAAAATCGCGGGGAGTCTCTGGCCGGGAGAGTCCAGGTAGCGCTCGGCGGGCAGCAGTGCGCAGGCCCCTCGGCTTCAACCGC
CACAATGCTGCCAGCAGCGCCAGGCAAGGGGCTTGGGAGCCCGGACCCCGCCCCCTGCGGCCCAGCGCCCCCAGGAAATACAAAAGATAT
AATAATGATATATGAAGAAGATGCTGAGGAATGGGCTCTGTACTTGACAGAAGTATTTTTACATGTTGTGAAAAGGGAAGCCATCCTGTT
ATATCGCTTGGAGAATTTCTCTTTTCGGCATTTGGAGTTGCTGAACTTAACGTCTTACAAATGTAAACTTTTGATATTATCAAATAGCCT
GCTTAGAGACCTAACTCCAAAGAAATGTCAGTTTCTGGAAAAGATACTTCATTCACCAAAAAGTGTAGTTACTTTGCTTTGTGGAGTGAA
GAGTTCAGATCAGCTCTATGAATTACTAAATATCTCTCAAAGCAGATGGGAGATCTCAACTGAACAGGAACCTGAAGACTACATCTCTGT
AATCCAGAGTATCATATTCAAAGATTCTGAAGACTACTTTGAGGTCAACATTCCAACAGACCTACGAGCAAAACATTCTGGGGAAATAAG
TGAGAGAAAGGAAATTGAAGAACTATCAGAAGCTTCAAGAAACACCATACCACTAGCAGTGGTGCTTCCCACTGAAATTCCATGTGAGAA
TCCTGGTGAAATATTCATAATTTTGAGAGATGAAGTAATTGGTGATACTGTAGAGGTTGAATTTACATCAAGTAATAAGCGCATTAGAAC
ACGGCCAGCCCTTTGGAATAAGAAAGTCTGGTGCATGAAAGCTTTAGAGTTTCCTGCTGGTTCAGTCCATGTCAATGTCTACTGTGATGG
AATCGTTAAAGCTACAACCAAAATTAAGTACTACCCAACAGCAAAGGCAAAGGAATGCCTATTCAGAATGGCAGATTCAGGAGAGAGTTT
GTGCCAGAATAGCATTGAAGAACTTGATGGTGTCCTTACATCCATATTCAAACATGAGATACCATATTATGAGTTCCAGTCTCTTCAAAC
TGAAATTTGTTCTCAAAACAAATATACTCATTTCAAAGAACTTCCAACTCTTCTCCACTGTGCAGCAAAATTTGGCTTAAAGAACCTGGC
TATTCATTTGCTTCAATGTTCAGGAGCAACCTGGGCATCTAAGATGAAAAATATGGAGGGTTCAGACCCCGCACATATTGCTGAAAGGCA
TGGTCACAAAGAACTCAAGAAAATCTTCGAAGACTTTTCAATCCAAGAAATTGACATAAATAATGAGCAAGAAAATGATTATGAAGAGGA
TATTGCCTCATTTTCCACATATATTCCTTCCACACAGAACCCAGCATTTCATCATGAAAGCAGGAAGACATACGGGCAGAGTGCAGATGG
AGCTGAGGCAAATGAAATGGAAGGGGAAGGAAAACAGAATGGATCAGGCATGGAGACCAAACACAGCCCACTAGAGGTTGGCAGTGAGAG
TTCTGAAGACCAGTATGATGACTTGTATGTGTTCATTCCTGGTGCTGATCCAGAAAATAATTCACAAGAGCCACTCATGAGCAGCAGACC
TCCTCTCCCCCCGCCGCGACCTGTAGCTAATGCCTTCCAACTGGAAAGACCTCACTTCACCTTACCAGGGACAATGGTGGAAGGCCAAAT
GGAAAGAAGTCAAAACTGGGGTCATCCTGGTGTTAGACAAGAAACAGGAGATGAACCCAAAGGAGAAAAAGAGAAGAAAGAAGAGGAAAA
AGAGCAGGAGGAGGAAGAAGACCCATATACTTTTGCTGAGATTGATGACAGTGAATATGACATGATATTGGCCAATCTGAGTATAAAGAA
AAAAACTGGGAGTCGGTCTTTCATTATAAATAGACCTCCTGCCCCCACACCCCGACCCACAAGTATACCTCCAAAAGAGGAAACTACACC
TTACATAGCTCAAGTGTTTCAACAAAAGACAGCCAGAAGACAATCTGATGATGACAAGTTCTGTGGTCTTCCTAAGAAACAAGATTGTTT
TTTCCATTTGCATTGCTTTCTGGGGAGTTAGAAGCATGAAACAACTCACCTCTCACCCTTGGAAATAACCTGAATTTGTACATAATTCTC
TTCTTTTAATGAGTTGTCCACACGCATATTATGACTGCATATTAAAATGTAATTATTTTATGTAATGCTTATATGAACTATTTCTTCAAT
GAAAAGTAAAATTACTTATTTACTATTGTTTGCCTTTCACATTTGTTATTTTCTATTAAAAATTAAAGTCAGTTTTGGTTACTTCCCCCC
TTTACTACAATTAAAAAAAGATTTCAAATATAATGATGTTATATTAACTGATAGCCTTATATGACAAGTATAAAAAGAAGGGATGAAACT
TAAAAACAGTAAAAACAAGAAGGAATATTGCCTTTACATCAATTTGAAAACAATGTTTCCTTTGATGTTTGCTAAAATTATGCATAGATA
CATGTTTGTAGTCATAAAAATGTATTACATTGGTTGTCTTCCTAAGGCCACAGTTACCTTTGCAATCCATATAACCTAAGAAGCTGCATT
CCAGAAAAAGACATCACTGAGGCCAGGCGCGGTGGCTCACCCCTGTAATCCCAGCACTTTGTGGGGCTGAGGTGGGCGGATCATGAGGTC
CAGAGATAGAGACCATCCTGGCCAACATGGTGAAGTCCTGTCTCTACTAAAAATATAAAAATTTAGCTGGACATGGTGGTGTGCGCCTGT
AGTCCCAGCTACTCTGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGCAGAAGTTGGAGTGAGTGGAGATTGCACCACTGCACTC
CAGCCTGGGCGACAGAGCGAGACTCCGTCTCAAAGAAAAAAGACATCACTGAAAGAAAAATGAACAGAATTTGTCAGAATTAGTTTTTTC
AACAGGTTACTTTGTCATACATTTCTCTAATATGCTTGGTCAATTTGTTTTGGCAGACTGGGCAGCATGCAGCAATTCTGCATTATTTAA

>In-frame_ENST00000322953_ENST00000342526_TCGA-HC-A6AL-01A_BANK1_chr4_102965064_+_AGMO_chr7_15240984_length(amino acids)=722AA_start in transcript=112_stop in transcript=2280
MRFLRPGRSLRGWQAGWGEPRAKGRENRGESLAGRVQVALGGQQCAGPSASTATMLPAAPGKGLGSPDPAPCGPAPPGNTKDIIMIYEED
AEEWALYLTEVFLHVVKREAILLYRLENFSFRHLELLNLTSYKCKLLILSNSLLRDLTPKKCQFLEKILHSPKSVVTLLCGVKSSDQLYE
LLNISQSRWEISTEQEPEDYISVIQSIIFKDSEDYFEVNIPTDLRAKHSGEISERKEIEELSEASRNTIPLAVVLPTEIPCENPGEIFII
LRDEVIGDTVEVEFTSSNKRIRTRPALWNKKVWCMKALEFPAGSVHVNVYCDGIVKATTKIKYYPTAKAKECLFRMADSGESLCQNSIEE
LDGVLTSIFKHEIPYYEFQSLQTEICSQNKYTHFKELPTLLHCAAKFGLKNLAIHLLQCSGATWASKMKNMEGSDPAHIAERHGHKELKK
IFEDFSIQEIDINNEQENDYEEDIASFSTYIPSTQNPAFHHESRKTYGQSADGAEANEMEGEGKQNGSGMETKHSPLEVGSESSEDQYDD
LYVFIPGADPENNSQEPLMSSRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGVRQETGDEPKGEKEKKEEEKEQEEEED
PYTFAEIDDSEYDMILANLSIKKKTGSRSFIINRPPAPTPRPTSIPPKEETTPYIAQVFQQKTARRQSDDDKFCGLPKKQDCFFHLHCFL

--------------------------------------------------------------
>In-frame_ENST00000428908_ENST00000342526_TCGA-HC-A6AL-01A_BANK1_chr4_102965064_+_AGMO_chr7_15240984_length(transcript)=2886nt_BP=1844nt
AAACCAAAGCGGCCTTTTGAGAAGGGATGTAAGAGCAGGCCCCTGAGCAGTTTCACTTCCTCTGGGCGCCCAGCAGAGCGGAGCCCTGGC
CTTGCGGGCATGAGCCCCGGGGCTGCGTTTCCTGAGACCTGGCCGCAGCCTCCGCGGGTGGCAAGCGGGCTGGGGAGAGCCGAGGGCCAA
AGGAAGAGAAAATCGCGGGGAGTCTCTGGCCGGGAGAGTCCAGGTAGCGCTCGGCGGGCAGCAGTGCGCAGGCCCCTCGGCTTCAACCGC
CACAATGCTGCCAGCAGCGCCAGGCAAGGGGCTTGGGAGCCCGGACCCCGCCCCCTGCGGCCCAGCGCCCCCAGATTCTGAAGACTACTT
TGAGGTCAACATTCCAACAGACCTACGAGCAAAACATTCTGGGGAAATAAGTGAGAGAAAGGAAATTGAAGAACTATCAGAAGCTTCAAG
AAACACCATACCACTAGCAGTGGTGCTTCCCACTGAAATTCCATGTGAGAATCCTGGTGAAATATTCATAATTTTGAGAGATGAAGTAAT
TGGTGATACTGTAGAGGTTGAATTTACATCAAGTAATAAGCGCATTAGAACACGGCCAGCCCTTTGGAATAAGAAAGTCTGGTGCATGAA
AGCTTTAGAGTTTCCTGCTGGTTCAGTCCATGTCAATGTCTACTGTGATGGAATCGTTAAAGCTACAACCAAAATTAAGTACTACCCAAC
AGCAAAGGCAAAGGAATGCCTATTCAGAATGGCAGATTCAGGAGAGAGTTTGTGCCAGAATAGCATTGAAGAACTTGATGGTGTCCTTAC
ATCCATATTCAAACATGAGATACCATATTATGAGTTCCAGTCTCTTCAAACTGAAATTTGTTCTCAAAACAAATATACTCATTTCAAAGA
ACTTCCAACTCTTCTCCACTGTGCAGCAAAATTTGGCTTAAAGAACCTGGCTATTCATTTGCTTCAATGTTCAGGAGCAACCTGGGCATC
TAAGATGAAAAATATGGAGGGTTCAGACCCCGCACATATTGCTGAAAGGCATGGTCACAAAGAACTCAAGAAAATCTTCGAAGACTTTTC
AATCCAAGAAATTGACATAAATAATGAGCAAGAAAATGATTATGAAGAGGATATTGCCTCATTTTCCACATATATTCCTTCCACACAGAA
CCCAGCATTTCATCATGAAAGCAGGAAGACATACGGGCAGAGTGCAGATGGAGCTGAGGCAAATGAAATGGAAGGGGAAGGAAAACAGAA
TGGATCAGGCATGGAGACCAAACACAGCCCACTAGAGGTTGGCAGTGAGAGTTCTGAAGACCAGTATGATGACTTGTATGTGTTCATTCC
TGGTGCTGATCCAGAAAATAATTCACAAGAGCCACTCATGAGCAGCAGACCTCCTCTCCCCCCGCCGCGACCTGTAGCTAATGCCTTCCA
ACTGGAAAGACCTCACTTCACCTTACCAGGGACAATGGTGGAAGGCCAAATGGAAAGAAGTCAAAACTGGGGTCATCCTGGTGTTAGACA
AGAAACAGGAGATGAACCCAAAGGAGAAAAAGAGAAGAAAGAAGAGGAAAAAGAGCAGGAGGAGGAAGAAGACCCATATACTTTTGCTGA
GATTGATGACAGTGAATATGACATGATATTGGCCAATCTGAGTATAAAGAAAAAAACTGGGAGTCGGTCTTTCATTATAAATAGACCTCC
TGCCCCCACACCCCGACCCACAAGTATACCTCCAAAAGAGGAAACTACACCTTACATAGCTCAAGTGTTTCAACAAAAGACAGCCAGAAG
ACAATCTGATGATGACAAGTTCTGTGGTCTTCCTAAGAAACAAGATTGTTTTTTCCATTTGCATTGCTTTCTGGGGAGTTAGAAGCATGA
AACAACTCACCTCTCACCCTTGGAAATAACCTGAATTTGTACATAATTCTCTTCTTTTAATGAGTTGTCCACACGCATATTATGACTGCA
TATTAAAATGTAATTATTTTATGTAATGCTTATATGAACTATTTCTTCAATGAAAAGTAAAATTACTTATTTACTATTGTTTGCCTTTCA
CATTTGTTATTTTCTATTAAAAATTAAAGTCAGTTTTGGTTACTTCCCCCCTTTACTACAATTAAAAAAAGATTTCAAATATAATGATGT
TATATTAACTGATAGCCTTATATGACAAGTATAAAAAGAAGGGATGAAACTTAAAAACAGTAAAAACAAGAAGGAATATTGCCTTTACAT
CAATTTGAAAACAATGTTTCCTTTGATGTTTGCTAAAATTATGCATAGATACATGTTTGTAGTCATAAAAATGTATTACATTGGTTGTCT
TCCTAAGGCCACAGTTACCTTTGCAATCCATATAACCTAAGAAGCTGCATTCCAGAAAAAGACATCACTGAGGCCAGGCGCGGTGGCTCA
CCCCTGTAATCCCAGCACTTTGTGGGGCTGAGGTGGGCGGATCATGAGGTCCAGAGATAGAGACCATCCTGGCCAACATGGTGAAGTCCT
GTCTCTACTAAAAATATAAAAATTTAGCTGGACATGGTGGTGTGCGCCTGTAGTCCCAGCTACTCTGGAGGCTGAGGCAGGAGAATCGCT
TGAACCTGGGAGGCAGAAGTTGGAGTGAGTGGAGATTGCACCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCCGTCTCAAAGAAAA
AAGACATCACTGAAAGAAAAATGAACAGAATTTGTCAGAATTAGTTTTTTCAACAGGTTACTTTGTCATACATTTCTCTAATATGCTTGG
TCAATTTGTTTTGGCAGACTGGGCAGCATGCAGCAATTCTGCATTATTTAAAGTTATCAGAACAATGTTAATTCTCTAAATAAAATTACC

>In-frame_ENST00000428908_ENST00000342526_TCGA-HC-A6AL-01A_BANK1_chr4_102965064_+_AGMO_chr7_15240984_length(amino acids)=589AA_start in transcript=112_stop in transcript=1881
MRFLRPGRSLRGWQAGWGEPRAKGRENRGESLAGRVQVALGGQQCAGPSASTATMLPAAPGKGLGSPDPAPCGPAPPDSEDYFEVNIPTD
LRAKHSGEISERKEIEELSEASRNTIPLAVVLPTEIPCENPGEIFIILRDEVIGDTVEVEFTSSNKRIRTRPALWNKKVWCMKALEFPAG
SVHVNVYCDGIVKATTKIKYYPTAKAKECLFRMADSGESLCQNSIEELDGVLTSIFKHEIPYYEFQSLQTEICSQNKYTHFKELPTLLHC
AAKFGLKNLAIHLLQCSGATWASKMKNMEGSDPAHIAERHGHKELKKIFEDFSIQEIDINNEQENDYEEDIASFSTYIPSTQNPAFHHES
RKTYGQSADGAEANEMEGEGKQNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGADPENNSQEPLMSSRPPLPPPRPVANAFQLERPHFT
LPGTMVEGQMERSQNWGHPGVRQETGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSEYDMILANLSIKKKTGSRSFIINRPPAPTPRPT

--------------------------------------------------------------
>In-frame_ENST00000508653_ENST00000342526_TCGA-HC-A6AL-01A_BANK1_chr4_102965064_+_AGMO_chr7_15240984_length(transcript)=2763nt_BP=1721nt
GAGACCTGGCCGCAGCCTCCGCGGGTGGCAAGCGGGCTGGGGAGAGCCGAGGGCCAAAGGAAGAGAAAATCGCGGGGAGTCTCTGGCCGG
GAGAGTCCAGGTAGCGCTCGGCGGGCAGCAGTGCGCAGGCCCCTCGGCTTCAACCGCCACAATGCTGCCAGCAGCGCCAGGCAAGGGGCT
TGGGAGCCCGGACCCCGCCCCCTGCGGCCCAGCGCCCCCAGATTCTGAAGACTACTTTGAGGTCAACATTCCAACAGACCTACGAGCAAA
ACATTCTGGGGAAATAAGTGAGAGAAAGGAAATTGAAGAACTATCAGAAGCTTCAAGAAACACCATACCACTAGCAGTGGTGCTTCCCAC
TGAAATTCCATGTGAGAATCCTGGTGAAATATTCATAATTTTGAGAGATGAAGTAATTGGTGATACTGTAGAGGTTGAATTTACATCAAG
TAATAAGCGCATTAGAACACGGCCAGCCCTTTGGAATAAGAAAGTCTGGTGCATGAAAGCTTTAGAGTTTCCTGCTGGTTCAGTCCATGT
CAATGTCTACTGTGATGGAATCGTTAAAGCTACAACCAAAATTAAGTACTACCCAACAGCAAAGGCAAAGGAATGCCTATTCAGAATGGC
AGATTCAGGAGAGAGTTTGTGCCAGAATAGCATTGAAGAACTTGATGGTGTCCTTACATCCATATTCAAACATGAGATACCATATTATGA
GTTCCAGTCTCTTCAAACTGAAATTTGTTCTCAAAACAAATATACTCATTTCAAAGAACTTCCAACTCTTCTCCACTGTGCAGCAAAATT
TGGCTTAAAGAACCTGGCTATTCATTTGCTTCAATGTTCAGGAGCAACCTGGGCATCTAAGATGAAAAATATGGAGGGTTCAGACCCCGC
ACATATTGCTGAAAGGCATGGTCACAAAGAACTCAAGAAAATCTTCGAAGACTTTTCAATCCAAGAAATTGACATAAATAATGAGCAAGA
AAATGATTATGAAGAGGATATTGCCTCATTTTCCACATATATTCCTTCCACACAGAACCCAGCATTTCATCATGAAAGCAGGAAGACATA
CGGGCAGAGTGCAGATGGAGCTGAGGCAAATGAAATGGAAGGGGAAGGAAAACAGAATGGATCAGGCATGGAGACCAAACACAGCCCACT
AGAGGTTGGCAGTGAGAGTTCTGAAGACCAGTATGATGACTTGTATGTGTTCATTCCTGGTGCTGATCCAGAAAATAATTCACAAGAGCC
ACTCATGAGCAGCAGACCTCCTCTCCCCCCGCCGCGACCTGTAGCTAATGCCTTCCAACTGGAAAGACCTCACTTCACCTTACCAGGGAC
AATGGTGGAAGGCCAAATGGAAAGAAGTCAAAACTGGGGTCATCCTGGTGTTAGACAAGAAACAGGAGATGAACCCAAAGGAGAAAAAGA
GAAGAAAGAAGAGGAAAAAGAGCAGGAGGAGGAAGAAGACCCATATACTTTTGCTGAGATTGATGACAGTGAATATGACATGATATTGGC
CAATCTGAGTATAAAGAAAAAAACTGGGAGTCGGTCTTTCATTATAAATAGACCTCCTGCCCCCACACCCCGACCCACAAGTATACCTCC
AAAAGAGGAAACTACACCTTACATAGCTCAAGTGTTTCAACAAAAGACAGCCAGAAGACAATCTGATGATGACAAGTTCTGTGGTCTTCC
TAAGAAACAAGATTGTTTTTTCCATTTGCATTGCTTTCTGGGGAGTTAGAAGCATGAAACAACTCACCTCTCACCCTTGGAAATAACCTG
AATTTGTACATAATTCTCTTCTTTTAATGAGTTGTCCACACGCATATTATGACTGCATATTAAAATGTAATTATTTTATGTAATGCTTAT
ATGAACTATTTCTTCAATGAAAAGTAAAATTACTTATTTACTATTGTTTGCCTTTCACATTTGTTATTTTCTATTAAAAATTAAAGTCAG
TTTTGGTTACTTCCCCCCTTTACTACAATTAAAAAAAGATTTCAAATATAATGATGTTATATTAACTGATAGCCTTATATGACAAGTATA
AAAAGAAGGGATGAAACTTAAAAACAGTAAAAACAAGAAGGAATATTGCCTTTACATCAATTTGAAAACAATGTTTCCTTTGATGTTTGC
TAAAATTATGCATAGATACATGTTTGTAGTCATAAAAATGTATTACATTGGTTGTCTTCCTAAGGCCACAGTTACCTTTGCAATCCATAT
AACCTAAGAAGCTGCATTCCAGAAAAAGACATCACTGAGGCCAGGCGCGGTGGCTCACCCCTGTAATCCCAGCACTTTGTGGGGCTGAGG
TGGGCGGATCATGAGGTCCAGAGATAGAGACCATCCTGGCCAACATGGTGAAGTCCTGTCTCTACTAAAAATATAAAAATTTAGCTGGAC
ATGGTGGTGTGCGCCTGTAGTCCCAGCTACTCTGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGCAGAAGTTGGAGTGAGTGGA
GATTGCACCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCCGTCTCAAAGAAAAAAGACATCACTGAAAGAAAAATGAACAGAATTT
GTCAGAATTAGTTTTTTCAACAGGTTACTTTGTCATACATTTCTCTAATATGCTTGGTCAATTTGTTTTGGCAGACTGGGCAGCATGCAG

>In-frame_ENST00000508653_ENST00000342526_TCGA-HC-A6AL-01A_BANK1_chr4_102965064_+_AGMO_chr7_15240984_length(amino acids)=558AA_start in transcript=82_stop in transcript=1758
MAGRVQVALGGQQCAGPSASTATMLPAAPGKGLGSPDPAPCGPAPPDSEDYFEVNIPTDLRAKHSGEISERKEIEELSEASRNTIPLAVV
LPTEIPCENPGEIFIILRDEVIGDTVEVEFTSSNKRIRTRPALWNKKVWCMKALEFPAGSVHVNVYCDGIVKATTKIKYYPTAKAKECLF
RMADSGESLCQNSIEELDGVLTSIFKHEIPYYEFQSLQTEICSQNKYTHFKELPTLLHCAAKFGLKNLAIHLLQCSGATWASKMKNMEGS
DPAHIAERHGHKELKKIFEDFSIQEIDINNEQENDYEEDIASFSTYIPSTQNPAFHHESRKTYGQSADGAEANEMEGEGKQNGSGMETKH
SPLEVGSESSEDQYDDLYVFIPGADPENNSQEPLMSSRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGVRQETGDEPKG
EKEKKEEEKEQEEEEDPYTFAEIDDSEYDMILANLSIKKKTGSRSFIINRPPAPTPRPTSIPPKEETTPYIAQVFQQKTARRQSDDDKFC

--------------------------------------------------------------
>In-frame_ENST00000444316_ENST00000342526_TCGA-HC-A6AL-01A_BANK1_chr4_102965064_+_AGMO_chr7_15240984_length(transcript)=3054nt_BP=2012nt
CTGGCCAACAAGGGCTGCAGAGGATGCACACATCAGGAAGAGGGTGGGGGACTACTTGCTTGCTGGTTTTGCTTGCATCTGATGAGTAGA
AATTCAGCCTATTCTTTGTTTTGGAAATACAAAAGATATAATAATGATATATGAAGAAGATGCTGAGGAATGGGCTCTGTACTTGACAGA
AGTATTTTTACATGTTGTGAAAAGGGAAGCCATCCTGTTATATCGCTTGGAGAATTTCTCTTTTCGGCATTTGGAGTTGCTGAACTTAAC
GTCTTACAAATGTAAACTTTTGATATTATCAAATAGCCTGCTTAGAGACCTAACTCCAAAGAAATGTCAGTTTCTGGAAAAGATACTTCA
TTCACCAAAAAGTGTAGTTACTTTGCTTTGTGGAGTGAAGAGTTCAGATCAGCTCTATGAATTACTAAATATCTCTCAAAGCAGATGGGA
GATCTCAACTGAACAGGAACCTGAAGACTACATCTCTGTAATCCAGAGTATCATATTCAAAGATTCTGAAGACTACTTTGAGGTCAACAT
TCCAACAGACCTACGAGCAAAACATTCTGGGGAAATAAGTGAGAGAAAGGAAATTGAAGAACTATCAGAAGCTTCAAGAAACACCATACC
ACTAGCAGTGGTGCTTCCCACTGAAATTCCATGTGAGAATCCTGGTGAAATATTCATAATTTTGAGAGATGAAGTAATTGGTGATACTGT
AGAGGTTGAATTTACATCAAGTAATAAGCGCATTAGAACACGGCCAGCCCTTTGGAATAAGAAAGTCTGGTGCATGAAAGCTTTAGAGTT
TCCTGCTGGTTCAGTCCATGTCAATGTCTACTGTGATGGAATCGTTAAAGCTACAACCAAAATTAAGTACTACCCAACAGCAAAGGCAAA
GGAATGCCTATTCAGAATGGCAGATTCAGGAGAGAGTTTGTGCCAGAATAGCATTGAAGAACTTGATGGTGTCCTTACATCCATATTCAA
ACATGAGATACCATATTATGAGTTCCAGTCTCTTCAAACTGAAATTTGTTCTCAAAACAAATATACTCATTTCAAAGAACTTCCAACTCT
TCTCCACTGTGCAGCAAAATTTGGCTTAAAGAACCTGGCTATTCATTTGCTTCAATGTTCAGGAGCAACCTGGGCATCTAAGATGAAAAA
TATGGAGGGTTCAGACCCCGCACATATTGCTGAAAGGCATGGTCACAAAGAACTCAAGAAAATCTTCGAAGACTTTTCAATCCAAGAAAT
TGACATAAATAATGAGCAAGAAAATGATTATGAAGAGGATATTGCCTCATTTTCCACATATATTCCTTCCACACAGAACCCAGCATTTCA
TCATGAAAGCAGGAAGACATACGGGCAGAGTGCAGATGGAGCTGAGGCAAATGAAATGGAAGGGGAAGGAAAACAGAATGGATCAGGCAT
GGAGACCAAACACAGCCCACTAGAGGTTGGCAGTGAGAGTTCTGAAGACCAGTATGATGACTTGTATGTGTTCATTCCTGGTGCTGATCC
AGAAAATAATTCACAAGAGCCACTCATGAGCAGCAGACCTCCTCTCCCCCCGCCGCGACCTGTAGCTAATGCCTTCCAACTGGAAAGACC
TCACTTCACCTTACCAGGGACAATGGTGGAAGGCCAAATGGAAAGAAGTCAAAACTGGGGTCATCCTGGTGTTAGACAAGAAACAGGAGA
TGAACCCAAAGGAGAAAAAGAGAAGAAAGAAGAGGAAAAAGAGCAGGAGGAGGAAGAAGACCCATATACTTTTGCTGAGATTGATGACAG
TGAATATGACATGATATTGGCCAATCTGAGTATAAAGAAAAAAACTGGGAGTCGGTCTTTCATTATAAATAGACCTCCTGCCCCCACACC
CCGACCCACAAGTATACCTCCAAAAGAGGAAACTACACCTTACATAGCTCAAGTGTTTCAACAAAAGACAGCCAGAAGACAATCTGATGA
TGACAAGTTCTGTGGTCTTCCTAAGAAACAAGATTGTTTTTTCCATTTGCATTGCTTTCTGGGGAGTTAGAAGCATGAAACAACTCACCT
CTCACCCTTGGAAATAACCTGAATTTGTACATAATTCTCTTCTTTTAATGAGTTGTCCACACGCATATTATGACTGCATATTAAAATGTA
ATTATTTTATGTAATGCTTATATGAACTATTTCTTCAATGAAAAGTAAAATTACTTATTTACTATTGTTTGCCTTTCACATTTGTTATTT
TCTATTAAAAATTAAAGTCAGTTTTGGTTACTTCCCCCCTTTACTACAATTAAAAAAAGATTTCAAATATAATGATGTTATATTAACTGA
TAGCCTTATATGACAAGTATAAAAAGAAGGGATGAAACTTAAAAACAGTAAAAACAAGAAGGAATATTGCCTTTACATCAATTTGAAAAC
AATGTTTCCTTTGATGTTTGCTAAAATTATGCATAGATACATGTTTGTAGTCATAAAAATGTATTACATTGGTTGTCTTCCTAAGGCCAC
AGTTACCTTTGCAATCCATATAACCTAAGAAGCTGCATTCCAGAAAAAGACATCACTGAGGCCAGGCGCGGTGGCTCACCCCTGTAATCC
CAGCACTTTGTGGGGCTGAGGTGGGCGGATCATGAGGTCCAGAGATAGAGACCATCCTGGCCAACATGGTGAAGTCCTGTCTCTACTAAA
AATATAAAAATTTAGCTGGACATGGTGGTGTGCGCCTGTAGTCCCAGCTACTCTGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAG
GCAGAAGTTGGAGTGAGTGGAGATTGCACCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCCGTCTCAAAGAAAAAAGACATCACTG
AAAGAAAAATGAACAGAATTTGTCAGAATTAGTTTTTTCAACAGGTTACTTTGTCATACATTTCTCTAATATGCTTGGTCAATTTGTTTT

>In-frame_ENST00000444316_ENST00000342526_TCGA-HC-A6AL-01A_BANK1_chr4_102965064_+_AGMO_chr7_15240984_length(amino acids)=638AA_start in transcript=133_stop in transcript=2049
MIYEEDAEEWALYLTEVFLHVVKREAILLYRLENFSFRHLELLNLTSYKCKLLILSNSLLRDLTPKKCQFLEKILHSPKSVVTLLCGVKS
SDQLYELLNISQSRWEISTEQEPEDYISVIQSIIFKDSEDYFEVNIPTDLRAKHSGEISERKEIEELSEASRNTIPLAVVLPTEIPCENP
GEIFIILRDEVIGDTVEVEFTSSNKRIRTRPALWNKKVWCMKALEFPAGSVHVNVYCDGIVKATTKIKYYPTAKAKECLFRMADSGESLC
QNSIEELDGVLTSIFKHEIPYYEFQSLQTEICSQNKYTHFKELPTLLHCAAKFGLKNLAIHLLQCSGATWASKMKNMEGSDPAHIAERHG
HKELKKIFEDFSIQEIDINNEQENDYEEDIASFSTYIPSTQNPAFHHESRKTYGQSADGAEANEMEGEGKQNGSGMETKHSPLEVGSESS
EDQYDDLYVFIPGADPENNSQEPLMSSRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGVRQETGDEPKGEKEKKEEEKE
QEEEEDPYTFAEIDDSEYDMILANLSIKKKTGSRSFIINRPPAPTPRPTSIPPKEETTPYIAQVFQQKTARRQSDDDKFCGLPKKQDCFF

--------------------------------------------------------------

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Fusion Gene PPI Analysis for BANK1-AGMO


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneBANK1chr4:102965064chr7:15240984ENST00000322953+11171_154656.3333333333334916.3333333333334ITPR2
HgeneBANK1chr4:102965064chr7:15240984ENST00000428908+10161_154523.3333333333334807.0ITPR2
HgeneBANK1chr4:102965064chr7:15240984ENST00000444316+11171_154626.3333333333334963.3333333333334ITPR2
HgeneBANK1chr4:102965064chr7:15240984ENST00000504592+15211_154641.3333333333334994.6666666666666ITPR2
HgeneBANK1chr4:102965064chr7:15240984ENST00000508653+10151_154523.3333333333334653.0ITPR2


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for BANK1-AGMO


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for BANK1-AGMO


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneBANK1C0024141Lupus Erythematosus, Systemic6CTD_human;ORPHANET
HgeneBANK1C0242380Libman-Sacks Disease1CTD_human
TgeneAGMOC0014544Epilepsy2GENOMICS_ENGLAND
TgeneAGMOC0025958Microcephaly2GENOMICS_ENGLAND
TgeneAGMOC3714756Intellectual Disability2GENOMICS_ENGLAND