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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TLE4-HDAC5 (FusionGDB2 ID:90494)

Fusion Gene Summary for TLE4-HDAC5

check button Fusion gene summary
Fusion gene informationFusion gene name: TLE4-HDAC5
Fusion gene ID: 90494
HgeneTgene
Gene symbol

TLE4

HDAC5

Gene ID

7091

10014

Gene nameTLE family member 4, transcriptional corepressorhistone deacetylase 5
SynonymsBCE-1|BCE1|E(spI)|E(spl)|ESG|ESG4|GRG4|Grg-4HD5|NY-CO-9
Cytomap

9q21.31

17q21.31

Type of geneprotein-codingprotein-coding
Descriptiontransducin-like enhancer protein 4B lymphocyte gene 1enhancer of split groucho 4groucho-related protein 4transducin like enhancer of split 4transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)transducin-like enhancer of split 4, homolog histone deacetylase 5antigen NY-CO-9
Modification date2020031320200313
UniProtAcc.

Q9UQL6

Ensembl transtripts involved in fusion geneENST00000376552, ENST00000376520, 
ENST00000376544, ENST00000376537, 
ENST00000376534, ENST00000265284, 
ENST00000455913, 		ENST00000225983, 
ENST00000393622, ENST00000336057, 
ENST00000586802, 
Fusion gene scores* DoF score7 X 6 X 2=8413 X 11 X 8=1144
# samples 714
** MAII scorelog2(7/84*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(14/1144*10)=-3.03058831983342
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TLE4 [Title/Abstract] AND HDAC5 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTLE4(82320857)-HDAC5(42165064), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneHDAC5

GO:0000122

negative regulation of transcription by RNA polymerase II

16236793

TgeneHDAC5

GO:0016575

histone deacetylation

10869435


check buttonFusion gene breakpoints across TLE4 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across HDAC5 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-06-0749-01ATLE4chr9

82320857

+HDAC5chr17

42165064

-


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Fusion Gene ORF analysis for TLE4-HDAC5

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000376552ENST00000225983TLE4chr9

82320857

+HDAC5chr17

42165064

-
In-frameENST00000376552ENST00000393622TLE4chr9

82320857

+HDAC5chr17

42165064

-
In-frameENST00000376552ENST00000336057TLE4chr9

82320857

+HDAC5chr17

42165064

-
In-frameENST00000376552ENST00000586802TLE4chr9

82320857

+HDAC5chr17

42165064

-
In-frameENST00000376520ENST00000225983TLE4chr9

82320857

+HDAC5chr17

42165064

-
In-frameENST00000376520ENST00000393622TLE4chr9

82320857

+HDAC5chr17

42165064

-
In-frameENST00000376520ENST00000336057TLE4chr9

82320857

+HDAC5chr17

42165064

-
In-frameENST00000376520ENST00000586802TLE4chr9

82320857

+HDAC5chr17

42165064

-
intron-3CDSENST00000376544ENST00000225983TLE4chr9

82320857

+HDAC5chr17

42165064

-
intron-3CDSENST00000376544ENST00000393622TLE4chr9

82320857

+HDAC5chr17

42165064

-
intron-3CDSENST00000376544ENST00000336057TLE4chr9

82320857

+HDAC5chr17

42165064

-
intron-3CDSENST00000376544ENST00000586802TLE4chr9

82320857

+HDAC5chr17

42165064

-
In-frameENST00000376537ENST00000225983TLE4chr9

82320857

+HDAC5chr17

42165064

-
In-frameENST00000376537ENST00000393622TLE4chr9

82320857

+HDAC5chr17

42165064

-
In-frameENST00000376537ENST00000336057TLE4chr9

82320857

+HDAC5chr17

42165064

-
In-frameENST00000376537ENST00000586802TLE4chr9

82320857

+HDAC5chr17

42165064

-
5UTR-3CDSENST00000376534ENST00000225983TLE4chr9

82320857

+HDAC5chr17

42165064

-
5UTR-3CDSENST00000376534ENST00000393622TLE4chr9

82320857

+HDAC5chr17

42165064

-
5UTR-3CDSENST00000376534ENST00000336057TLE4chr9

82320857

+HDAC5chr17

42165064

-
5UTR-3CDSENST00000376534ENST00000586802TLE4chr9

82320857

+HDAC5chr17

42165064

-
In-frameENST00000265284ENST00000225983TLE4chr9

82320857

+HDAC5chr17

42165064

-
In-frameENST00000265284ENST00000393622TLE4chr9

82320857

+HDAC5chr17

42165064

-
In-frameENST00000265284ENST00000336057TLE4chr9

82320857

+HDAC5chr17

42165064

-
In-frameENST00000265284ENST00000586802TLE4chr9

82320857

+HDAC5chr17

42165064

-
intron-3CDSENST00000455913ENST00000225983TLE4chr9

82320857

+HDAC5chr17

42165064

-
intron-3CDSENST00000455913ENST00000393622TLE4chr9

82320857

+HDAC5chr17

42165064

-
intron-3CDSENST00000455913ENST00000336057TLE4chr9

82320857

+HDAC5chr17

42165064

-
intron-3CDSENST00000455913ENST00000586802TLE4chr9

82320857

+HDAC5chr17

42165064

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000376552TLE4chr982320857+ENST00000225983HDAC5chr1742165064-5201180110183570850
ENST00000376552TLE4chr982320857+ENST00000393622HDAC5chr1742165064-5194180110183570850
ENST00000376552TLE4chr982320857+ENST00000336057HDAC5chr1742165064-4938180110183315765
ENST00000376552TLE4chr982320857+ENST00000586802HDAC5chr1742165064-3653180110183570850
ENST00000376520TLE4chr982320857+ENST00000225983HDAC5chr1742165064-501116118283380850
ENST00000376520TLE4chr982320857+ENST00000393622HDAC5chr1742165064-500416118283380850
ENST00000376520TLE4chr982320857+ENST00000336057HDAC5chr1742165064-474816118283125765
ENST00000376520TLE4chr982320857+ENST00000586802HDAC5chr1742165064-346316118283380850
ENST00000376537TLE4chr982320857+ENST00000225983HDAC5chr1742165064-43599591762728850
ENST00000376537TLE4chr982320857+ENST00000393622HDAC5chr1742165064-43529591762728850
ENST00000376537TLE4chr982320857+ENST00000336057HDAC5chr1742165064-40969591762473765
ENST00000376537TLE4chr982320857+ENST00000586802HDAC5chr1742165064-28119591762728850
ENST00000265284TLE4chr982320857+ENST00000225983HDAC5chr1742165064-4154754462523825
ENST00000265284TLE4chr982320857+ENST00000393622HDAC5chr1742165064-4147754462523825
ENST00000265284TLE4chr982320857+ENST00000336057HDAC5chr1742165064-3891754462268740
ENST00000265284TLE4chr982320857+ENST00000586802HDAC5chr1742165064-2606754462523825

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000376552ENST00000225983TLE4chr982320857+HDAC5chr1742165064-0.0013761870.99862385
ENST00000376552ENST00000393622TLE4chr982320857+HDAC5chr1742165064-0.0014027370.9985972
ENST00000376552ENST00000336057TLE4chr982320857+HDAC5chr1742165064-0.0017625420.9982375
ENST00000376552ENST00000586802TLE4chr982320857+HDAC5chr1742165064-0.0031400230.99686
ENST00000376520ENST00000225983TLE4chr982320857+HDAC5chr1742165064-0.0013286630.9986714
ENST00000376520ENST00000393622TLE4chr982320857+HDAC5chr1742165064-0.0013541550.99864584
ENST00000376520ENST00000336057TLE4chr982320857+HDAC5chr1742165064-0.0017047280.99829525
ENST00000376520ENST00000586802TLE4chr982320857+HDAC5chr1742165064-0.003131470.99686855
ENST00000376537ENST00000225983TLE4chr982320857+HDAC5chr1742165064-0.0022633380.9977367
ENST00000376537ENST00000393622TLE4chr982320857+HDAC5chr1742165064-0.0023125820.99768746
ENST00000376537ENST00000336057TLE4chr982320857+HDAC5chr1742165064-0.0028501330.9971499
ENST00000376537ENST00000586802TLE4chr982320857+HDAC5chr1742165064-0.0078951330.9921049
ENST00000265284ENST00000225983TLE4chr982320857+HDAC5chr1742165064-0.0014982930.9985018
ENST00000265284ENST00000393622TLE4chr982320857+HDAC5chr1742165064-0.0015427020.9984573
ENST00000265284ENST00000336057TLE4chr982320857+HDAC5chr1742165064-0.0013428130.9986572
ENST00000265284ENST00000586802TLE4chr982320857+HDAC5chr1742165064-0.0054853770.9945147

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Fusion Genomic Features for TLE4-HDAC5


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TLE4-HDAC5


check button Go to

FGviewer for the breakpoints of chr9:82320857-chr17:42165064

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.HDAC5

Q9UQL6

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. Serves as a corepressor of RARA and causes its deacetylation (PubMed:28167758). In association with RARA, plays a role in the repression of microRNA-10a and thereby in the inflammatory response (PubMed:28167758). {ECO:0000269|PubMed:24413532, ECO:0000269|PubMed:28167758}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTLE4chr9:82320857chr17:42165064ENST00000376537+1021137_204261.0806.0RegionGP domain
HgeneTLE4chr9:82320857chr17:42165064ENST00000376537+10211_136261.0806.0RegionQ domain
HgeneTLE4chr9:82320857chr17:42165064ENST00000376552+1020137_204261.0774.0RegionGP domain
HgeneTLE4chr9:82320857chr17:42165064ENST00000376552+10201_136261.0774.0RegionQ domain
TgeneHDAC5chr9:82320857chr17:42165064ENST0000022598311271099_1104534.01124.0Compositional biasNote=Poly-Ala
TgeneHDAC5chr9:82320857chr17:42165064ENST000002259831127596_599534.01124.0Compositional biasNote=Poly-Glu
TgeneHDAC5chr9:82320857chr17:42165064ENST0000033605711251099_1104533.01038.0Compositional biasNote=Poly-Ala
TgeneHDAC5chr9:82320857chr17:42165064ENST000003360571125596_599533.01038.0Compositional biasNote=Poly-Glu
TgeneHDAC5chr9:82320857chr17:42165064ENST0000039362211271099_1104533.01123.0Compositional biasNote=Poly-Ala
TgeneHDAC5chr9:82320857chr17:42165064ENST000003936221127596_599533.01123.0Compositional biasNote=Poly-Glu
TgeneHDAC5chr9:82320857chr17:42165064ENST0000058680211271099_1104533.01123.0Compositional biasNote=Poly-Ala
TgeneHDAC5chr9:82320857chr17:42165064ENST000005868021127596_599533.01123.0Compositional biasNote=Poly-Glu
TgeneHDAC5chr9:82320857chr17:42165064ENST0000022598311271081_1122534.01124.0MotifNote=Nuclear export signal
TgeneHDAC5chr9:82320857chr17:42165064ENST0000033605711251081_1122533.01038.0MotifNote=Nuclear export signal
TgeneHDAC5chr9:82320857chr17:42165064ENST0000039362211271081_1122533.01123.0MotifNote=Nuclear export signal
TgeneHDAC5chr9:82320857chr17:42165064ENST0000058680211271081_1122533.01123.0MotifNote=Nuclear export signal
TgeneHDAC5chr9:82320857chr17:42165064ENST000002259831127684_1028534.01124.0RegionNote=Histone deacetylase
TgeneHDAC5chr9:82320857chr17:42165064ENST000003360571125684_1028533.01038.0RegionNote=Histone deacetylase
TgeneHDAC5chr9:82320857chr17:42165064ENST000003936221127684_1028533.01123.0RegionNote=Histone deacetylase
TgeneHDAC5chr9:82320857chr17:42165064ENST000005868021127684_1028533.01123.0RegionNote=Histone deacetylase

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTLE4chr9:82320857chr17:42165064ENST00000376537+1021205_274261.0806.0RegionCcN domain
HgeneTLE4chr9:82320857chr17:42165064ENST00000376537+1021275_452261.0806.0RegionSP domain
HgeneTLE4chr9:82320857chr17:42165064ENST00000376552+1020205_274261.0774.0RegionCcN domain
HgeneTLE4chr9:82320857chr17:42165064ENST00000376552+1020275_452261.0774.0RegionSP domain
HgeneTLE4chr9:82320857chr17:42165064ENST00000376537+1021485_523261.0806.0RepeatNote=WD 1
HgeneTLE4chr9:82320857chr17:42165064ENST00000376537+1021531_570261.0806.0RepeatNote=WD 2
HgeneTLE4chr9:82320857chr17:42165064ENST00000376537+1021575_614261.0806.0RepeatNote=WD 3
HgeneTLE4chr9:82320857chr17:42165064ENST00000376537+1021617_656261.0806.0RepeatNote=WD 4
HgeneTLE4chr9:82320857chr17:42165064ENST00000376537+1021658_697261.0806.0RepeatNote=WD 5
HgeneTLE4chr9:82320857chr17:42165064ENST00000376537+1021699_738261.0806.0RepeatNote=WD 6
HgeneTLE4chr9:82320857chr17:42165064ENST00000376537+1021740_773261.0806.0RepeatNote=WD 7
HgeneTLE4chr9:82320857chr17:42165064ENST00000376552+1020485_523261.0774.0RepeatNote=WD 1
HgeneTLE4chr9:82320857chr17:42165064ENST00000376552+1020531_570261.0774.0RepeatNote=WD 2
HgeneTLE4chr9:82320857chr17:42165064ENST00000376552+1020575_614261.0774.0RepeatNote=WD 3
HgeneTLE4chr9:82320857chr17:42165064ENST00000376552+1020617_656261.0774.0RepeatNote=WD 4
HgeneTLE4chr9:82320857chr17:42165064ENST00000376552+1020658_697261.0774.0RepeatNote=WD 5
HgeneTLE4chr9:82320857chr17:42165064ENST00000376552+1020699_738261.0774.0RepeatNote=WD 6
HgeneTLE4chr9:82320857chr17:42165064ENST00000376552+1020740_773261.0774.0RepeatNote=WD 7
TgeneHDAC5chr9:82320857chr17:42165064ENST00000225983112747_52534.01124.0Compositional biasNote=Poly-Gly
TgeneHDAC5chr9:82320857chr17:42165064ENST00000225983112785_92534.01124.0Compositional biasNote=Poly-Gln
TgeneHDAC5chr9:82320857chr17:42165064ENST00000336057112547_52533.01038.0Compositional biasNote=Poly-Gly
TgeneHDAC5chr9:82320857chr17:42165064ENST00000336057112585_92533.01038.0Compositional biasNote=Poly-Gln
TgeneHDAC5chr9:82320857chr17:42165064ENST00000393622112747_52533.01123.0Compositional biasNote=Poly-Gly
TgeneHDAC5chr9:82320857chr17:42165064ENST00000393622112785_92533.01123.0Compositional biasNote=Poly-Gln
TgeneHDAC5chr9:82320857chr17:42165064ENST00000586802112747_52533.01123.0Compositional biasNote=Poly-Gly
TgeneHDAC5chr9:82320857chr17:42165064ENST00000586802112785_92533.01123.0Compositional biasNote=Poly-Gln


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Fusion Gene Sequence for TLE4-HDAC5


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000376552_ENST00000225983_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(transcript)=5201nt_BP=1801nt
GGAGAGCTCGCCAGAGCGCTCGCATGGCGGGCCGGTGATTGTAGTCAATCTGGCCGTATTCTCAGGCAGGGTCGCCCGGGGCGGACTACA
TCTCCCGGGATGCTGCGCGGCCGCCCCGCGGAAGATTGTGAATATGTATCAGAATGTTAATGATTAGCTGCTGCTAAATTTGGTCAAAGA
AGTCACCTACACAGAGCGTGTTGTTAGAGCTGTGCTGAGCGGGTGTTTGGGTTGTTGGCTGCTTTCTTCCCCCTTTCTCACACACTTGTA
TATTATTTTGAGGTGGTGTTCGCAGAGTTTGAAAGGAGAGAGAATTAAAAAAAAAAGCCGCAAGCGTTTCACTCTTTTATTTTTATAATC
CCCTTCAATTTGGGGTTAAAAAAAAGACAAGAAAACAGGAAGGAAGAGAAATAAGGAAATGAGATGTGGTAAAAGAAGCTAAAAGGTGCC
TTTTAAAAGATCGTTGCTGTGAAGTGAAAAAAATCTCCAGAGAAACCAAAAAGCACCGCCGAGACCTCTTCCGAACCAAAGGAGTTTGTG
TTTGCTTTTAGGGAAGAAGAAAGATCATTCATTCGGAGGAATAACAACCAATTAAAAGACAAATAAAAAAAGTTTGGAGTGGGACGCAGA
GCGAGCGAGAGGAGCTGCCGGCGGGCGGTGGGGCGCGGAGCCCGCACTTTCCCGGCCGGGTGAGCGGCGGCCGCGGCGCCGGGCTCGGCG
GGTGCGCCTCGGCGGAGCGAACGTCGGAGCGTTGCCTTGGGAGACGCGCGCCGGACAATGCCCGCGGCGGGCCAGTGACGCCCGCGGGGA
ATGCGGAGCGGCCCGGCAGCCGGCACCCAGCCGCCGCCGCGCGTTCCTGCCGCCCGTGTCACGCGAGACCCGGCGGGGGCCGGGACCGCC
CGAGCCGCCCCTCAGACCGAGCCGGCCGCCTCCGCTGCCGCGGCCGCCTCCTCTTCGGGGTCATTAAAGCCAATGAGCCGCGCGCCTCTG
CCGAGCGCAGCCAACTAAATCGGCTTGGATGATTCGCGACCTGAGCAAGATGTACCCGCAGACCAGACACCCAGCACCGCATCAGCCTGC
TCAACCCTTTAAATTTACAATTTCCGAATCCTGTGATCGGATTAAGGAAGAGTTTCAGTTTTTACAGGCTCAATACCACAGTCTGAAGCT
GGAATGTGAGAAACTCGCCAGTGAGAAGACAGAGATGCAGCGGCATTATGTCATGTATTATGAAATGTCCTATGGGTTGAATATAGAAAT
GCACAAGCAGGCAGAGATTGTCAAGAGGCTGAATGCTATCTGTGCACAAGTCATTCCTTTCCTGTCCCAAGAGCACCAGCAACAAGTGGT
GCAGGCTGTGGAACGGGCCAAGCAGGTGACCATGGCAGAACTGAACGCCATCATTGGGCAACAACTCCAGGCCCAGCATTTATCACATGG
ACATGGTCTCCCCGTACCTCTGACTCCACACCCTTCAGGGCTCCAGCCCCCTGCCATTCCACCCATCGGTAGCAGTGCCGGGCTTCTGGC
CCTCTCCAGTGCTCTAGGAGGTCAGTCCCATCTTCCAATTAAAGATGAGAAGAAGCACCATGACAATGATCACCAAAGAGACAGAGACTC
CATCAAGAGCTCTTCAGTATCCCCATCAGCCAGTTTCCGAGGTGCTGAGAAGCACAGAAACTCCGCAGACTACTCCTCAGAGAGCAAAAA
GCAGAAAACTGAAGAAAAGGAAATTGCAGCTCGTTATGACAGCGATGGTGAGAAAAGTGATGACAACTTGGTGGTTGACGTTTCCAATGA
GATCCTCACCAAGACAGGGGAGCTGCCCAGGCAGCCCACCACCCACCCTGAGGAGACAGAGGAGGAGCTGACGGAGCAGCAGGAGGTCTT
GCTGGGGGAGGGAGCCCTGACCATGCCCCGGGAGGGCTCCACAGAGAGTGAGAGCACACAGGAAGACCTGGAGGAGGAGGACGAGGAAGA
CGATGGGGAGGAGGAGGAGGATTGCATCCAGGTTAAGGACGAGGAGGGCGAGAGTGGTGCTGAGGAGGGGCCCGACTTGGAGGAGCCTGG
TGCTGGATACAAAAAACTGTTCTCAGATGCCCAGCCGCTGCAGCCTTTGCAGGTGTACCAGGCGCCCCTCAGCCTGGCCACTGTGCCCCA
CCAGGCCCTGGGCCGTACCCAGTCCTCCCCTGCTGCCCCTGGGGGCATGAAGAGCCCCCCAGACCAGCCCGTCAAGCACCTCTTCACCAC
AGGTGTGGTCTACGACACGTTCATGCTAAAGCACCAGTGCATGTGCGGGAACACACACGTGCACCCTGAGCATGCTGGCCGGATCCAGAG
CATCTGGTCCCGGCTGCAGGAGACAGGCCTGCTTAGCAAGTGCGAGCGGATCCGAGGTCGCAAAGCCACGCTAGATGAGATCCAGACAGT
GCACTCTGAATACCACACCCTGCTCTATGGGACCAGTCCCCTCAACCGGCAGAAGCTAGACAGCAAGAAGTTGCTCGGCCCCATCAGCCA
GAAGATGTATGCTGTGCTGCCTTGTGGGGGCATCGGGGTGGACAGTGACACCGTGTGGAATGAGATGCACTCCTCCAGTGCTGTGCGCAT
GGCAGTGGGCTGCCTGCTGGAGCTGGCCTTCAAGGTGGCTGCAGGAGAGCTCAAGAATGGATTTGCCATCATCCGGCCCCCAGGACACCA
CGCCGAGGAATCCACAGCCATGGGATTCTGCTTCTTCAACTCTGTAGCCATCACCGCAAAACTCCTACAGCAGAAGTTGAACGTGGGCAA
GGTCCTCATCGTGGACTGGGACATTCACCATGGCAATGGCACCCAGCAGGCGTTCTACAATGACCCCTCTGTGCTCTACATCTCTCTGCA
TCGCTATGACAACGGGAACTTCTTTCCAGGCTCTGGGGCTCCTGAAGAGGTTGGTGGAGGACCAGGCGTGGGGTACAATGTGAACGTGGC
ATGGACAGGAGGTGTGGACCCCCCCATTGGAGACGTGGAGTACCTTACAGCCTTCAGGACAGTGGTGATGCCCATTGCCCACGAGTTCTC
ACCTGATGTGGTCCTAGTCTCCGCCGGGTTTGATGCTGTTGAAGGACATCTGTCTCCTCTGGGTGGCTACTCTGTCACCGCCAGATGTTT
TGGCCACTTGACCAGGCAGCTGATGACCCTGGCAGGGGGCCGGGTGGTGCTGGCCCTGGAGGGAGGCCATGACTTGACCGCCATCTGTGA
TGCCTCTGAGGCTTGTGTCTCGGCTCTGCTCAGTGTAGAGCTGCAGCCCTTGGATGAGGCAGTCTTGCAGCAAAAGCCCAACATCAACGC
AGTGGCCACGCTAGAGAAAGTCATCGAGATCCAGAGCAAACACTGGAGCTGTGTGCAGAAGTTCGCCGCTGGTCTGGGCCGGTCCCTGCG
AGAGGCCCAAGCAGGTGAGACCGAGGAGGCCGAGACTGTGAGCGCCATGGCCTTGCTGTCGGTGGGGGCCGAGCAGGCCCAGGCTGCGGC
AGCCCGGGAACACAGCCCCAGGCCGGCAGAGGAGCCCATGGAGCAGGAGCCTGCCCTGTGACGCCCCGGCCCCCATCCCTCTGGGCTTCA
CCATTGTGATTTTGTTTATTTTTTCTATTAAAAACAAAAAGTCACACATTCAACAAGGTGTGCCGTGTGGGTCTCTCAGCCTTGCCCCTC
CTGCTCCTCTACGCTGCCTCAGGCCCCCAGCCCTGTGGCTTCCACCTCAGCTCTAGAAGCCTGCTCCCTCTGCAGGGGGTGGTGGTGTCT
TCCCAGCCCTGTCCCATGTGTCCCTCCCCCCATTTTCCTGCATTCTGTCTGTCCTTTTCCTCCTTGGAGCCTGGGCCAGCTCAAGGTGGG
CACGGGGGCCCAGACAGTACTCTCCAGTTCTGGGGCCCCCCGAGTGAGGAGGGAACGGGAAGTCGGTGCCTTGGTTTCAGCTGATTTGGG
GGGAAATGCCTTAATTTCACTCTCCTCCCTTCTCCAGCCTCAGGGGAGGATCTGGAGGATCCACTACTGTCTTTAAGATGCAGAGTGGAG
GGGAGGTGGGCACCCACCCTGCGATTCTCCACCCTTTCCCCTTCTTTCGTCCTCACCATCTCTGCAGACCCCTCTCCTCCTCCTTCCTCT
TGGTCTCAGCACTGATGGGAGGCTGGTGCCCAAGCTGTGGCCTGCAGTCTGTGAGGAGGGCTGTCTTGCCTCACACTCCTCACAGCCTAC
TTCCCCTTCCCCGGGGCTGAGAGGGTGAAAGTGTGTGGGGAAGGAGAGGACTGGTTTCCTGGGTTCTCAGGGGCCAGGAGGAGTAACAGA
ACCAGGTCTGCTCCCCACCTTACTCGGATGGCCTCCCTGCCCCTCTGCTGGCACAGCCTGGGCAAGGGGAGAAGGTGGTCCCTGCAGAGG
GGCTCCAGGCTGGTGAGAGCCCCCCTGCTGTCAGGACCAGATTTTCCCAGCCATCCAGCATGCTGCGGGGAGAAGGGGCAGAGGCTCACC
TCCCTCCTGGGGCCTTTTGTTTTGGATCCTGGGGATGGTGAGAATGGAGGTTCTAGAAGGGGTAAGGCCAGAACCCAGGGATCCAGGAGT
CGGCTCTCAGCTGGAGCTTCCATACCTTCTGGGCTCCCTTTGCTGACCACCAGCCCAAGGGAGCTAAGACCAGGAGGGGGCTGGGCGCTG
TCCCTTCTCTTTCCCAGGAGCCCTGCCAGGGGCTGTGGGCCTACAAGGCTTCCAGGGGATGCCATCCAGCCTGTAGGAAACCAAAGATGG
GAAGTGGCTCCTAGGGGGCTGACTCTTCCTTCCTCCTCCTCCCCAGTACCACATATACTTTCTCTCCTTCTATCTCCAGGGCCCCACCAA
TCTGTTTACATATTTATTATCCTATGGGGGCCTGAGCAGGATTGAGGGAGCCAGGGGAGGGGCAGGAGTCCCAGCACCATCGGTTCATAG
TGTGCTTGTGTGTTTGTTTTAGATCCTCCTGGGGGATGGGGATGGGGCCAGGCTCAGTGTACTAGGCCTCTCTGTGCTGAGCCCCAGGCT
CCCGGCCCCTTACCCACTCTCTCCCTGTGGCTGGTCTGGTTCTCATGTAAACCCACTCCTTGCTTTGTCTCCCTGGATATGGATTTCAGT

>In-frame_ENST00000376552_ENST00000225983_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(amino acids)=850AA_start in transcript=1018_stop in transcript=3570
MIRDLSKMYPQTRHPAPHQPAQPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQAEIVKR
LNAICAQVIPFLSQEHQQQVVQAVERAKQVTMAELNAIIGQQLQAQHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQS
HLPIKDEKKHHDNDHQRDRDSIKSSSVSPSASFRGAEKHRNSADYSSESKKQKTEEKEIAARYDSDGEKSDDNLVVDVSNEILTKTGELP
RQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSD
AQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETG
LLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELA
FKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFP
GSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMT
LAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEE

--------------------------------------------------------------
>In-frame_ENST00000376552_ENST00000393622_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(transcript)=5194nt_BP=1801nt
GGAGAGCTCGCCAGAGCGCTCGCATGGCGGGCCGGTGATTGTAGTCAATCTGGCCGTATTCTCAGGCAGGGTCGCCCGGGGCGGACTACA
TCTCCCGGGATGCTGCGCGGCCGCCCCGCGGAAGATTGTGAATATGTATCAGAATGTTAATGATTAGCTGCTGCTAAATTTGGTCAAAGA
AGTCACCTACACAGAGCGTGTTGTTAGAGCTGTGCTGAGCGGGTGTTTGGGTTGTTGGCTGCTTTCTTCCCCCTTTCTCACACACTTGTA
TATTATTTTGAGGTGGTGTTCGCAGAGTTTGAAAGGAGAGAGAATTAAAAAAAAAAGCCGCAAGCGTTTCACTCTTTTATTTTTATAATC
CCCTTCAATTTGGGGTTAAAAAAAAGACAAGAAAACAGGAAGGAAGAGAAATAAGGAAATGAGATGTGGTAAAAGAAGCTAAAAGGTGCC
TTTTAAAAGATCGTTGCTGTGAAGTGAAAAAAATCTCCAGAGAAACCAAAAAGCACCGCCGAGACCTCTTCCGAACCAAAGGAGTTTGTG
TTTGCTTTTAGGGAAGAAGAAAGATCATTCATTCGGAGGAATAACAACCAATTAAAAGACAAATAAAAAAAGTTTGGAGTGGGACGCAGA
GCGAGCGAGAGGAGCTGCCGGCGGGCGGTGGGGCGCGGAGCCCGCACTTTCCCGGCCGGGTGAGCGGCGGCCGCGGCGCCGGGCTCGGCG
GGTGCGCCTCGGCGGAGCGAACGTCGGAGCGTTGCCTTGGGAGACGCGCGCCGGACAATGCCCGCGGCGGGCCAGTGACGCCCGCGGGGA
ATGCGGAGCGGCCCGGCAGCCGGCACCCAGCCGCCGCCGCGCGTTCCTGCCGCCCGTGTCACGCGAGACCCGGCGGGGGCCGGGACCGCC
CGAGCCGCCCCTCAGACCGAGCCGGCCGCCTCCGCTGCCGCGGCCGCCTCCTCTTCGGGGTCATTAAAGCCAATGAGCCGCGCGCCTCTG
CCGAGCGCAGCCAACTAAATCGGCTTGGATGATTCGCGACCTGAGCAAGATGTACCCGCAGACCAGACACCCAGCACCGCATCAGCCTGC
TCAACCCTTTAAATTTACAATTTCCGAATCCTGTGATCGGATTAAGGAAGAGTTTCAGTTTTTACAGGCTCAATACCACAGTCTGAAGCT
GGAATGTGAGAAACTCGCCAGTGAGAAGACAGAGATGCAGCGGCATTATGTCATGTATTATGAAATGTCCTATGGGTTGAATATAGAAAT
GCACAAGCAGGCAGAGATTGTCAAGAGGCTGAATGCTATCTGTGCACAAGTCATTCCTTTCCTGTCCCAAGAGCACCAGCAACAAGTGGT
GCAGGCTGTGGAACGGGCCAAGCAGGTGACCATGGCAGAACTGAACGCCATCATTGGGCAACAACTCCAGGCCCAGCATTTATCACATGG
ACATGGTCTCCCCGTACCTCTGACTCCACACCCTTCAGGGCTCCAGCCCCCTGCCATTCCACCCATCGGTAGCAGTGCCGGGCTTCTGGC
CCTCTCCAGTGCTCTAGGAGGTCAGTCCCATCTTCCAATTAAAGATGAGAAGAAGCACCATGACAATGATCACCAAAGAGACAGAGACTC
CATCAAGAGCTCTTCAGTATCCCCATCAGCCAGTTTCCGAGGTGCTGAGAAGCACAGAAACTCCGCAGACTACTCCTCAGAGAGCAAAAA
GCAGAAAACTGAAGAAAAGGAAATTGCAGCTCGTTATGACAGCGATGGTGAGAAAAGTGATGACAACTTGGTGGTTGACGTTTCCAATGA
GATCCTCACCAAGACAGGGGAGCTGCCCAGGCAGCCCACCACCCACCCTGAGGAGACAGAGGAGGAGCTGACGGAGCAGCAGGAGGTCTT
GCTGGGGGAGGGAGCCCTGACCATGCCCCGGGAGGGCTCCACAGAGAGTGAGAGCACACAGGAAGACCTGGAGGAGGAGGACGAGGAAGA
CGATGGGGAGGAGGAGGAGGATTGCATCCAGGTTAAGGACGAGGAGGGCGAGAGTGGTGCTGAGGAGGGGCCCGACTTGGAGGAGCCTGG
TGCTGGATACAAAAAACTGTTCTCAGATGCCCAGCCGCTGCAGCCTTTGCAGGTGTACCAGGCGCCCCTCAGCCTGGCCACTGTGCCCCA
CCAGGCCCTGGGCCGTACCCAGTCCTCCCCTGCTGCCCCTGGGGGCATGAAGAGCCCCCCAGACCAGCCCGTCAAGCACCTCTTCACCAC
AGGTGTGGTCTACGACACGTTCATGCTAAAGCACCAGTGCATGTGCGGGAACACACACGTGCACCCTGAGCATGCTGGCCGGATCCAGAG
CATCTGGTCCCGGCTGCAGGAGACAGGCCTGCTTAGCAAGTGCGAGCGGATCCGAGGTCGCAAAGCCACGCTAGATGAGATCCAGACAGT
GCACTCTGAATACCACACCCTGCTCTATGGGACCAGTCCCCTCAACCGGCAGAAGCTAGACAGCAAGAAGTTGCTCGGCCCCATCAGCCA
GAAGATGTATGCTGTGCTGCCTTGTGGGGGCATCGGGGTGGACAGTGACACCGTGTGGAATGAGATGCACTCCTCCAGTGCTGTGCGCAT
GGCAGTGGGCTGCCTGCTGGAGCTGGCCTTCAAGGTGGCTGCAGGAGAGCTCAAGAATGGATTTGCCATCATCCGGCCCCCAGGACACCA
CGCCGAGGAATCCACAGCCATGGGATTCTGCTTCTTCAACTCTGTAGCCATCACCGCAAAACTCCTACAGCAGAAGTTGAACGTGGGCAA
GGTCCTCATCGTGGACTGGGACATTCACCATGGCAATGGCACCCAGCAGGCGTTCTACAATGACCCCTCTGTGCTCTACATCTCTCTGCA
TCGCTATGACAACGGGAACTTCTTTCCAGGCTCTGGGGCTCCTGAAGAGGTTGGTGGAGGACCAGGCGTGGGGTACAATGTGAACGTGGC
ATGGACAGGAGGTGTGGACCCCCCCATTGGAGACGTGGAGTACCTTACAGCCTTCAGGACAGTGGTGATGCCCATTGCCCACGAGTTCTC
ACCTGATGTGGTCCTAGTCTCCGCCGGGTTTGATGCTGTTGAAGGACATCTGTCTCCTCTGGGTGGCTACTCTGTCACCGCCAGATGTTT
TGGCCACTTGACCAGGCAGCTGATGACCCTGGCAGGGGGCCGGGTGGTGCTGGCCCTGGAGGGAGGCCATGACTTGACCGCCATCTGTGA
TGCCTCTGAGGCTTGTGTCTCGGCTCTGCTCAGTGTAGAGCTGCAGCCCTTGGATGAGGCAGTCTTGCAGCAAAAGCCCAACATCAACGC
AGTGGCCACGCTAGAGAAAGTCATCGAGATCCAGAGCAAACACTGGAGCTGTGTGCAGAAGTTCGCCGCTGGTCTGGGCCGGTCCCTGCG
AGAGGCCCAAGCAGGTGAGACCGAGGAGGCCGAGACTGTGAGCGCCATGGCCTTGCTGTCGGTGGGGGCCGAGCAGGCCCAGGCTGCGGC
AGCCCGGGAACACAGCCCCAGGCCGGCAGAGGAGCCCATGGAGCAGGAGCCTGCCCTGTGACGCCCCGGCCCCCATCCCTCTGGGCTTCA
CCATTGTGATTTTGTTTATTTTTTCTATTAAAAACAAAAAGTCACACATTCAACAAGGTGTGCCGTGTGGGTCTCTCAGCCTTGCCCCTC
CTGCTCCTCTACGCTGCCTCAGGCCCCCAGCCCTGTGGCTTCCACCTCAGCTCTAGAAGCCTGCTCCCTCTGCAGGGGGTGGTGGTGTCT
TCCCAGCCCTGTCCCATGTGTCCCTCCCCCCATTTTCCTGCATTCTGTCTGTCCTTTTCCTCCTTGGAGCCTGGGCCAGCTCAAGGTGGG
CACGGGGGCCCAGACAGTACTCTCCAGTTCTGGGGCCCCCCGAGTGAGGAGGGAACGGGAAGTCGGTGCCTTGGTTTCAGCTGATTTGGG
GGGAAATGCCTTAATTTCACTCTCCTCCCTTCTCCAGCCTCAGGGGAGGATCTGGAGGATCCACTACTGTCTTTAAGATGCAGAGTGGAG
GGGAGGTGGGCACCCACCCTGCGATTCTCCACCCTTTCCCCTTCTTTCGTCCTCACCATCTCTGCAGACCCCTCTCCTCCTCCTTCCTCT
TGGTCTCAGCACTGATGGGAGGCTGGTGCCCAAGCTGTGGCCTGCAGTCTGTGAGGAGGGCTGTCTTGCCTCACACTCCTCACAGCCTAC
TTCCCCTTCCCCGGGGCTGAGAGGGTGAAAGTGTGTGGGGAAGGAGAGGACTGGTTTCCTGGGTTCTCAGGGGCCAGGAGGAGTAACAGA
ACCAGGTCTGCTCCCCACCTTACTCGGATGGCCTCCCTGCCCCTCTGCTGGCACAGCCTGGGCAAGGGGAGAAGGTGGTCCCTGCAGAGG
GGCTCCAGGCTGGTGAGAGCCCCCCTGCTGTCAGGACCAGATTTTCCCAGCCATCCAGCATGCTGCGGGGAGAAGGGGCAGAGGCTCACC
TCCCTCCTGGGGCCTTTTGTTTTGGATCCTGGGGATGGTGAGAATGGAGGTTCTAGAAGGGGTAAGGCCAGAACCCAGGGATCCAGGAGT
CGGCTCTCAGCTGGAGCTTCCATACCTTCTGGGCTCCCTTTGCTGACCACCAGCCCAAGGGAGCTAAGACCAGGAGGGGGCTGGGCGCTG
TCCCTTCTCTTTCCCAGGAGCCCTGCCAGGGGCTGTGGGCCTACAAGGCTTCCAGGGGATGCCATCCAGCCTGTAGGAAACCAAAGATGG
GAAGTGGCTCCTAGGGGGCTGACTCTTCCTTCCTCCTCCTCCCCAGTACCACATATACTTTCTCTCCTTCTATCTCCAGGGCCCCACCAA
TCTGTTTACATATTTATTATCCTATGGGGGCCTGAGCAGGATTGAGGGAGCCAGGGGAGGGGCAGGAGTCCCAGCACCATCGGTTCATAG
TGTGCTTGTGTGTTTGTTTTAGATCCTCCTGGGGGATGGGGATGGGGCCAGGCTCAGTGTACTAGGCCTCTCTGTGCTGAGCCCCAGGCT
CCCGGCCCCTTACCCACTCTCTCCCTGTGGCTGGTCTGGTTCTCATGTAAACCCACTCCTTGCTTTGTCTCCCTGGATATGGATTTCAGT

>In-frame_ENST00000376552_ENST00000393622_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(amino acids)=850AA_start in transcript=1018_stop in transcript=3570
MIRDLSKMYPQTRHPAPHQPAQPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQAEIVKR
LNAICAQVIPFLSQEHQQQVVQAVERAKQVTMAELNAIIGQQLQAQHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQS
HLPIKDEKKHHDNDHQRDRDSIKSSSVSPSASFRGAEKHRNSADYSSESKKQKTEEKEIAARYDSDGEKSDDNLVVDVSNEILTKTGELP
RQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSD
AQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETG
LLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELA
FKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFP
GSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMT
LAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEE

--------------------------------------------------------------
>In-frame_ENST00000376552_ENST00000336057_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(transcript)=4938nt_BP=1801nt
GGAGAGCTCGCCAGAGCGCTCGCATGGCGGGCCGGTGATTGTAGTCAATCTGGCCGTATTCTCAGGCAGGGTCGCCCGGGGCGGACTACA
TCTCCCGGGATGCTGCGCGGCCGCCCCGCGGAAGATTGTGAATATGTATCAGAATGTTAATGATTAGCTGCTGCTAAATTTGGTCAAAGA
AGTCACCTACACAGAGCGTGTTGTTAGAGCTGTGCTGAGCGGGTGTTTGGGTTGTTGGCTGCTTTCTTCCCCCTTTCTCACACACTTGTA
TATTATTTTGAGGTGGTGTTCGCAGAGTTTGAAAGGAGAGAGAATTAAAAAAAAAAGCCGCAAGCGTTTCACTCTTTTATTTTTATAATC
CCCTTCAATTTGGGGTTAAAAAAAAGACAAGAAAACAGGAAGGAAGAGAAATAAGGAAATGAGATGTGGTAAAAGAAGCTAAAAGGTGCC
TTTTAAAAGATCGTTGCTGTGAAGTGAAAAAAATCTCCAGAGAAACCAAAAAGCACCGCCGAGACCTCTTCCGAACCAAAGGAGTTTGTG
TTTGCTTTTAGGGAAGAAGAAAGATCATTCATTCGGAGGAATAACAACCAATTAAAAGACAAATAAAAAAAGTTTGGAGTGGGACGCAGA
GCGAGCGAGAGGAGCTGCCGGCGGGCGGTGGGGCGCGGAGCCCGCACTTTCCCGGCCGGGTGAGCGGCGGCCGCGGCGCCGGGCTCGGCG
GGTGCGCCTCGGCGGAGCGAACGTCGGAGCGTTGCCTTGGGAGACGCGCGCCGGACAATGCCCGCGGCGGGCCAGTGACGCCCGCGGGGA
ATGCGGAGCGGCCCGGCAGCCGGCACCCAGCCGCCGCCGCGCGTTCCTGCCGCCCGTGTCACGCGAGACCCGGCGGGGGCCGGGACCGCC
CGAGCCGCCCCTCAGACCGAGCCGGCCGCCTCCGCTGCCGCGGCCGCCTCCTCTTCGGGGTCATTAAAGCCAATGAGCCGCGCGCCTCTG
CCGAGCGCAGCCAACTAAATCGGCTTGGATGATTCGCGACCTGAGCAAGATGTACCCGCAGACCAGACACCCAGCACCGCATCAGCCTGC
TCAACCCTTTAAATTTACAATTTCCGAATCCTGTGATCGGATTAAGGAAGAGTTTCAGTTTTTACAGGCTCAATACCACAGTCTGAAGCT
GGAATGTGAGAAACTCGCCAGTGAGAAGACAGAGATGCAGCGGCATTATGTCATGTATTATGAAATGTCCTATGGGTTGAATATAGAAAT
GCACAAGCAGGCAGAGATTGTCAAGAGGCTGAATGCTATCTGTGCACAAGTCATTCCTTTCCTGTCCCAAGAGCACCAGCAACAAGTGGT
GCAGGCTGTGGAACGGGCCAAGCAGGTGACCATGGCAGAACTGAACGCCATCATTGGGCAACAACTCCAGGCCCAGCATTTATCACATGG
ACATGGTCTCCCCGTACCTCTGACTCCACACCCTTCAGGGCTCCAGCCCCCTGCCATTCCACCCATCGGTAGCAGTGCCGGGCTTCTGGC
CCTCTCCAGTGCTCTAGGAGGTCAGTCCCATCTTCCAATTAAAGATGAGAAGAAGCACCATGACAATGATCACCAAAGAGACAGAGACTC
CATCAAGAGCTCTTCAGTATCCCCATCAGCCAGTTTCCGAGGTGCTGAGAAGCACAGAAACTCCGCAGACTACTCCTCAGAGAGCAAAAA
GCAGAAAACTGAAGAAAAGGAAATTGCAGCTCGTTATGACAGCGATGGTGAGAAAAGTGATGACAACTTGGTGGTTGACGTTTCCAATGA
GATCCTCACCAAGACAGGGGAGCTGCCCAGGCAGCCCACCACCCACCCTGAGGAGACAGAGGAGGAGCTGACGGAGCAGCAGGAGGTCTT
GCTGGGGGAGGGAGCCCTGACCATGCCCCGGGAGGGCTCCACAGAGAGTGAGAGCACACAGGAAGACCTGGAGGAGGAGGACGAGGAAGA
CGATGGGGAGGAGGAGGAGGATTGCATCCAGGTTAAGGACGAGGAGGGCGAGAGTGGTGCTGAGGAGGGGCCCGACTTGGAGGAGCCTGG
TGCTGGATACAAAAAACTGTTCTCAGATGCCCAGCCGCTGCAGCCTTTGCAGGTGTACCAGGCGCCCCTCAGCCTGGCCACTGTGCCCCA
CCAGGCCCTGGGCCGTACCCAGTCCTCCCCTGCTGCCCCTGGGGGCATGAAGAGCCCCCCAGACCAGCCCGTCAAGCACCTCTTCACCAC
AGGCCCCATCAGCCAGAAGATGTATGCTGTGCTGCCTTGTGGGGGCATCGGGGTGGACAGTGACACCGTGTGGAATGAGATGCACTCCTC
CAGTGCTGTGCGCATGGCAGTGGGCTGCCTGCTGGAGCTGGCCTTCAAGGTGGCTGCAGGAGAGCTCAAGAATGGATTTGCCATCATCCG
GCCCCCAGGACACCACGCCGAGGAATCCACAGCCATGGGATTCTGCTTCTTCAACTCTGTAGCCATCACCGCAAAACTCCTACAGCAGAA
GTTGAACGTGGGCAAGGTCCTCATCGTGGACTGGGACATTCACCATGGCAATGGCACCCAGCAGGCGTTCTACAATGACCCCTCTGTGCT
CTACATCTCTCTGCATCGCTATGACAACGGGAACTTCTTTCCAGGCTCTGGGGCTCCTGAAGAGGTTGGTGGAGGACCAGGCGTGGGGTA
CAATGTGAACGTGGCATGGACAGGAGGTGTGGACCCCCCCATTGGAGACGTGGAGTACCTTACAGCCTTCAGGACAGTGGTGATGCCCAT
TGCCCACGAGTTCTCACCTGATGTGGTCCTAGTCTCCGCCGGGTTTGATGCTGTTGAAGGACATCTGTCTCCTCTGGGTGGCTACTCTGT
CACCGCCAGATGTTTTGGCCACTTGACCAGGCAGCTGATGACCCTGGCAGGGGGCCGGGTGGTGCTGGCCCTGGAGGGAGGCCATGACTT
GACCGCCATCTGTGATGCCTCTGAGGCTTGTGTCTCGGCTCTGCTCAGTGTAGAGCTGCAGCCCTTGGATGAGGCAGTCTTGCAGCAAAA
GCCCAACATCAACGCAGTGGCCACGCTAGAGAAAGTCATCGAGATCCAGAGCAAACACTGGAGCTGTGTGCAGAAGTTCGCCGCTGGTCT
GGGCCGGTCCCTGCGAGAGGCCCAAGCAGGTGAGACCGAGGAGGCCGAGACTGTGAGCGCCATGGCCTTGCTGTCGGTGGGGGCCGAGCA
GGCCCAGGCTGCGGCAGCCCGGGAACACAGCCCCAGGCCGGCAGAGGAGCCCATGGAGCAGGAGCCTGCCCTGTGACGCCCCGGCCCCCA
TCCCTCTGGGCTTCACCATTGTGATTTTGTTTATTTTTTCTATTAAAAACAAAAAGTCACACATTCAACAAGGTGTGCCGTGTGGGTCTC
TCAGCCTTGCCCCTCCTGCTCCTCTACGCTGCCTCAGGCCCCCAGCCCTGTGGCTTCCACCTCAGCTCTAGAAGCCTGCTCCCTCTGCAG
GGGGTGGTGGTGTCTTCCCAGCCCTGTCCCATGTGTCCCTCCCCCCATTTTCCTGCATTCTGTCTGTCCTTTTCCTCCTTGGAGCCTGGG
CCAGCTCAAGGTGGGCACGGGGGCCCAGACAGTACTCTCCAGTTCTGGGGCCCCCCGAGTGAGGAGGGAACGGGAAGTCGGTGCCTTGGT
TTCAGCTGATTTGGGGGGAAATGCCTTAATTTCACTCTCCTCCCTTCTCCAGCCTCAGGGGAGGATCTGGAGGATCCACTACTGTCTTTA
AGATGCAGAGTGGAGGGGAGGTGGGCACCCACCCTGCGATTCTCCACCCTTTCCCCTTCTTTCGTCCTCACCATCTCTGCAGACCCCTCT
CCTCCTCCTTCCTCTTGGTCTCAGCACTGATGGGAGGCTGGTGCCCAAGCTGTGGCCTGCAGTCTGTGAGGAGGGCTGTCTTGCCTCACA
CTCCTCACAGCCTACTTCCCCTTCCCCGGGGCTGAGAGGGTGAAAGTGTGTGGGGAAGGAGAGGACTGGTTTCCTGGGTTCTCAGGGGCC
AGGAGGAGTAACAGAACCAGGTCTGCTCCCCACCTTACTCGGATGGCCTCCCTGCCCCTCTGCTGGCACAGCCTGGGCAAGGGGAGAAGG
TGGTCCCTGCAGAGGGGCTCCAGGCTGGTGAGAGCCCCCCTGCTGTCAGGACCAGATTTTCCCAGCCATCCAGCATGCTGCGGGGAGAAG
GGGCAGAGGCTCACCTCCCTCCTGGGGCCTTTTGTTTTGGATCCTGGGGATGGTGAGAATGGAGGTTCTAGAAGGGGTAAGGCCAGAACC
CAGGGATCCAGGAGTCGGCTCTCAGCTGGAGCTTCCATACCTTCTGGGCTCCCTTTGCTGACCACCAGCCCAAGGGAGCTAAGACCAGGA
GGGGGCTGGGCGCTGTCCCTTCTCTTTCCCAGGAGCCCTGCCAGGGGCTGTGGGCCTACAAGGCTTCCAGGGGATGCCATCCAGCCTGTA
GGAAACCAAAGATGGGAAGTGGCTCCTAGGGGGCTGACTCTTCCTTCCTCCTCCTCCCCAGTACCACATATACTTTCTCTCCTTCTATCT
CCAGGGCCCCACCAATCTGTTTACATATTTATTATCCTATGGGGGCCTGAGCAGGATTGAGGGAGCCAGGGGAGGGGCAGGAGTCCCAGC
ACCATCGGTTCATAGTGTGCTTGTGTGTTTGTTTTAGATCCTCCTGGGGGATGGGGATGGGGCCAGGCTCAGTGTACTAGGCCTCTCTGT
GCTGAGCCCCAGGCTCCCGGCCCCTTACCCACTCTCTCCCTGTGGCTGGTCTGGTTCTCATGTAAACCCACTCCTTGCTTTGTCTCCCTG

>In-frame_ENST00000376552_ENST00000336057_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(amino acids)=765AA_start in transcript=1018_stop in transcript=3315
MIRDLSKMYPQTRHPAPHQPAQPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQAEIVKR
LNAICAQVIPFLSQEHQQQVVQAVERAKQVTMAELNAIIGQQLQAQHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQS
HLPIKDEKKHHDNDHQRDRDSIKSSSVSPSASFRGAEKHRNSADYSSESKKQKTEEKEIAARYDSDGEKSDDNLVVDVSNEILTKTGELP
RQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSD
AQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLFTTGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGC
LLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDN
GNFFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLT
RQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQA

--------------------------------------------------------------
>In-frame_ENST00000376552_ENST00000586802_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(transcript)=3653nt_BP=1801nt
GGAGAGCTCGCCAGAGCGCTCGCATGGCGGGCCGGTGATTGTAGTCAATCTGGCCGTATTCTCAGGCAGGGTCGCCCGGGGCGGACTACA
TCTCCCGGGATGCTGCGCGGCCGCCCCGCGGAAGATTGTGAATATGTATCAGAATGTTAATGATTAGCTGCTGCTAAATTTGGTCAAAGA
AGTCACCTACACAGAGCGTGTTGTTAGAGCTGTGCTGAGCGGGTGTTTGGGTTGTTGGCTGCTTTCTTCCCCCTTTCTCACACACTTGTA
TATTATTTTGAGGTGGTGTTCGCAGAGTTTGAAAGGAGAGAGAATTAAAAAAAAAAGCCGCAAGCGTTTCACTCTTTTATTTTTATAATC
CCCTTCAATTTGGGGTTAAAAAAAAGACAAGAAAACAGGAAGGAAGAGAAATAAGGAAATGAGATGTGGTAAAAGAAGCTAAAAGGTGCC
TTTTAAAAGATCGTTGCTGTGAAGTGAAAAAAATCTCCAGAGAAACCAAAAAGCACCGCCGAGACCTCTTCCGAACCAAAGGAGTTTGTG
TTTGCTTTTAGGGAAGAAGAAAGATCATTCATTCGGAGGAATAACAACCAATTAAAAGACAAATAAAAAAAGTTTGGAGTGGGACGCAGA
GCGAGCGAGAGGAGCTGCCGGCGGGCGGTGGGGCGCGGAGCCCGCACTTTCCCGGCCGGGTGAGCGGCGGCCGCGGCGCCGGGCTCGGCG
GGTGCGCCTCGGCGGAGCGAACGTCGGAGCGTTGCCTTGGGAGACGCGCGCCGGACAATGCCCGCGGCGGGCCAGTGACGCCCGCGGGGA
ATGCGGAGCGGCCCGGCAGCCGGCACCCAGCCGCCGCCGCGCGTTCCTGCCGCCCGTGTCACGCGAGACCCGGCGGGGGCCGGGACCGCC
CGAGCCGCCCCTCAGACCGAGCCGGCCGCCTCCGCTGCCGCGGCCGCCTCCTCTTCGGGGTCATTAAAGCCAATGAGCCGCGCGCCTCTG
CCGAGCGCAGCCAACTAAATCGGCTTGGATGATTCGCGACCTGAGCAAGATGTACCCGCAGACCAGACACCCAGCACCGCATCAGCCTGC
TCAACCCTTTAAATTTACAATTTCCGAATCCTGTGATCGGATTAAGGAAGAGTTTCAGTTTTTACAGGCTCAATACCACAGTCTGAAGCT
GGAATGTGAGAAACTCGCCAGTGAGAAGACAGAGATGCAGCGGCATTATGTCATGTATTATGAAATGTCCTATGGGTTGAATATAGAAAT
GCACAAGCAGGCAGAGATTGTCAAGAGGCTGAATGCTATCTGTGCACAAGTCATTCCTTTCCTGTCCCAAGAGCACCAGCAACAAGTGGT
GCAGGCTGTGGAACGGGCCAAGCAGGTGACCATGGCAGAACTGAACGCCATCATTGGGCAACAACTCCAGGCCCAGCATTTATCACATGG
ACATGGTCTCCCCGTACCTCTGACTCCACACCCTTCAGGGCTCCAGCCCCCTGCCATTCCACCCATCGGTAGCAGTGCCGGGCTTCTGGC
CCTCTCCAGTGCTCTAGGAGGTCAGTCCCATCTTCCAATTAAAGATGAGAAGAAGCACCATGACAATGATCACCAAAGAGACAGAGACTC
CATCAAGAGCTCTTCAGTATCCCCATCAGCCAGTTTCCGAGGTGCTGAGAAGCACAGAAACTCCGCAGACTACTCCTCAGAGAGCAAAAA
GCAGAAAACTGAAGAAAAGGAAATTGCAGCTCGTTATGACAGCGATGGTGAGAAAAGTGATGACAACTTGGTGGTTGACGTTTCCAATGA
GATCCTCACCAAGACAGGGGAGCTGCCCAGGCAGCCCACCACCCACCCTGAGGAGACAGAGGAGGAGCTGACGGAGCAGCAGGAGGTCTT
GCTGGGGGAGGGAGCCCTGACCATGCCCCGGGAGGGCTCCACAGAGAGTGAGAGCACACAGGAAGACCTGGAGGAGGAGGACGAGGAAGA
CGATGGGGAGGAGGAGGAGGATTGCATCCAGGTTAAGGACGAGGAGGGCGAGAGTGGTGCTGAGGAGGGGCCCGACTTGGAGGAGCCTGG
TGCTGGATACAAAAAACTGTTCTCAGATGCCCAGCCGCTGCAGCCTTTGCAGGTGTACCAGGCGCCCCTCAGCCTGGCCACTGTGCCCCA
CCAGGCCCTGGGCCGTACCCAGTCCTCCCCTGCTGCCCCTGGGGGCATGAAGAGCCCCCCAGACCAGCCCGTCAAGCACCTCTTCACCAC
AGGTGTGGTCTACGACACGTTCATGCTAAAGCACCAGTGCATGTGCGGGAACACACACGTGCACCCTGAGCATGCTGGCCGGATCCAGAG
CATCTGGTCCCGGCTGCAGGAGACAGGCCTGCTTAGCAAGTGCGAGCGGATCCGAGGTCGCAAAGCCACGCTAGATGAGATCCAGACAGT
GCACTCTGAATACCACACCCTGCTCTATGGGACCAGTCCCCTCAACCGGCAGAAGCTAGACAGCAAGAAGTTGCTCGGCCCCATCAGCCA
GAAGATGTATGCTGTGCTGCCTTGTGGGGGCATCGGGGTGGACAGTGACACCGTGTGGAATGAGATGCACTCCTCCAGTGCTGTGCGCAT
GGCAGTGGGCTGCCTGCTGGAGCTGGCCTTCAAGGTGGCTGCAGGAGAGCTCAAGAATGGATTTGCCATCATCCGGCCCCCAGGACACCA
CGCCGAGGAATCCACAGCCATGGGATTCTGCTTCTTCAACTCTGTAGCCATCACCGCAAAACTCCTACAGCAGAAGTTGAACGTGGGCAA
GGTCCTCATCGTGGACTGGGACATTCACCATGGCAATGGCACCCAGCAGGCGTTCTACAATGACCCCTCTGTGCTCTACATCTCTCTGCA
TCGCTATGACAACGGGAACTTCTTTCCAGGCTCTGGGGCTCCTGAAGAGGTTGGTGGAGGACCAGGCGTGGGGTACAATGTGAACGTGGC
ATGGACAGGAGGTGTGGACCCCCCCATTGGAGACGTGGAGTACCTTACAGCCTTCAGGACAGTGGTGATGCCCATTGCCCACGAGTTCTC
ACCTGATGTGGTCCTAGTCTCCGCCGGGTTTGATGCTGTTGAAGGACATCTGTCTCCTCTGGGTGGCTACTCTGTCACCGCCAGATGTTT
TGGCCACTTGACCAGGCAGCTGATGACCCTGGCAGGGGGCCGGGTGGTGCTGGCCCTGGAGGGAGGCCATGACTTGACCGCCATCTGTGA
TGCCTCTGAGGCTTGTGTCTCGGCTCTGCTCAGTGTAGAGCTGCAGCCCTTGGATGAGGCAGTCTTGCAGCAAAAGCCCAACATCAACGC
AGTGGCCACGCTAGAGAAAGTCATCGAGATCCAGAGCAAACACTGGAGCTGTGTGCAGAAGTTCGCCGCTGGTCTGGGCCGGTCCCTGCG
AGAGGCCCAAGCAGGTGAGACCGAGGAGGCCGAGACTGTGAGCGCCATGGCCTTGCTGTCGGTGGGGGCCGAGCAGGCCCAGGCTGCGGC
AGCCCGGGAACACAGCCCCAGGCCGGCAGAGGAGCCCATGGAGCAGGAGCCTGCCCTGTGACGCCCCGGCCCCCATCCCTCTGGGCTTCA

>In-frame_ENST00000376552_ENST00000586802_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(amino acids)=850AA_start in transcript=1018_stop in transcript=3570
MIRDLSKMYPQTRHPAPHQPAQPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQAEIVKR
LNAICAQVIPFLSQEHQQQVVQAVERAKQVTMAELNAIIGQQLQAQHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQS
HLPIKDEKKHHDNDHQRDRDSIKSSSVSPSASFRGAEKHRNSADYSSESKKQKTEEKEIAARYDSDGEKSDDNLVVDVSNEILTKTGELP
RQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSD
AQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETG
LLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELA
FKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFP
GSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMT
LAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEE

--------------------------------------------------------------
>In-frame_ENST00000376520_ENST00000225983_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(transcript)=5011nt_BP=1611nt
ACAGAGCGTGTTGTTAGAGCTGTGCTGAGCGGGTGTTTGGGTTGTTGGCTGCTTTCTTCCCCCTTTCTCACACACTTGTATATTATTTTG
AGGTGGTGTTCGCAGAGTTTGAAAGGAGAGAGAATTAAAAAAAAAAGCCGCAAGCGTTTCACTCTTTTATTTTTATAATCCCCTTCAATT
TGGGGTTAAAAAAAAGACAAGAAAACAGGAAGGAAGAGAAATAAGGAAATGAGATGTGGTAAAAGAAGCTAAAAGGTGCCTTTTAAAAGA
TCGTTGCTGTGAAGTGAAAAAAATCTCCAGAGAAACCAAAAAGCACCGCCGAGACCTCTTCCGAACCAAAGGAGTTTGTGTTTGCTTTTA
GGGAAGAAGAAAGATCATTCATTCGGAGGAATAACAACCAATTAAAAGACAAATAAAAAAAGTTTGGAGTGGGACGCAGAGCGAGCGAGA
GGAGCTGCCGGCGGGCGGTGGGGCGCGGAGCCCGCACTTTCCCGGCCGGGTGAGCGGCGGCCGCGGCGCCGGGCTCGGCGGGTGCGCCTC
GGCGGAGCGAACGTCGGAGCGTTGCCTTGGGAGACGCGCGCCGGACAATGCCCGCGGCGGGCCAGTGACGCCCGCGGGGAATGCGGAGCG
GCCCGGCAGCCGGCACCCAGCCGCCGCCGCGCGTTCCTGCCGCCCGTGTCACGCGAGACCCGGCGGGGGCCGGGACCGCCCGAGCCGCCC
CTCAGACCGAGCCGGCCGCCTCCGCTGCCGCGGCCGCCTCCTCTTCGGGGTCATTAAAGCCAATGAGCCGCGCGCCTCTGCCGAGCGCAG
CCAACTAAATCGGCTTGGATGATTCGCGACCTGAGCAAGATGTACCCGCAGACCAGACACCCAGCACCGCATCAGCCTGCTCAACCCTTT
AAATTTACAATTTCCGAATCCTGTGATCGGATTAAGGAAGAGTTTCAGTTTTTACAGGCTCAATACCACAGTCTGAAGCTGGAATGTGAG
AAACTCGCCAGTGAGAAGACAGAGATGCAGCGGCATTATGTCATGTATTATGAAATGTCCTATGGGTTGAATATAGAAATGCACAAGCAG
GCAGAGATTGTCAAGAGGCTGAATGCTATCTGTGCACAAGTCATTCCTTTCCTGTCCCAAGAGCACCAGCAACAAGTGGTGCAGGCTGTG
GAACGGGCCAAGCAGGTGACCATGGCAGAACTGAACGCCATCATTGGGCAACAACTCCAGGCCCAGCATTTATCACATGGACATGGTCTC
CCCGTACCTCTGACTCCACACCCTTCAGGGCTCCAGCCCCCTGCCATTCCACCCATCGGTAGCAGTGCCGGGCTTCTGGCCCTCTCCAGT
GCTCTAGGAGGTCAGTCCCATCTTCCAATTAAAGATGAGAAGAAGCACCATGACAATGATCACCAAAGAGAGAGAGACAAACTCAACCAC
AAAAGTTTATCCCCATCAGCCAGTTTCCGAGGTGCTGAGAAGCACAGAAACTCCGCAGACTACTCCTCAGAGAGCAAAAAGCAGAAAACT
GAAGAAAAGGAAATTGCAGCTCGTTATGACAGCGATGGTGAGAAAAGTGATGACAACTTGGTGGTTGACGTTTCCAATGAGATCCTCACC
AAGACAGGGGAGCTGCCCAGGCAGCCCACCACCCACCCTGAGGAGACAGAGGAGGAGCTGACGGAGCAGCAGGAGGTCTTGCTGGGGGAG
GGAGCCCTGACCATGCCCCGGGAGGGCTCCACAGAGAGTGAGAGCACACAGGAAGACCTGGAGGAGGAGGACGAGGAAGACGATGGGGAG
GAGGAGGAGGATTGCATCCAGGTTAAGGACGAGGAGGGCGAGAGTGGTGCTGAGGAGGGGCCCGACTTGGAGGAGCCTGGTGCTGGATAC
AAAAAACTGTTCTCAGATGCCCAGCCGCTGCAGCCTTTGCAGGTGTACCAGGCGCCCCTCAGCCTGGCCACTGTGCCCCACCAGGCCCTG
GGCCGTACCCAGTCCTCCCCTGCTGCCCCTGGGGGCATGAAGAGCCCCCCAGACCAGCCCGTCAAGCACCTCTTCACCACAGGTGTGGTC
TACGACACGTTCATGCTAAAGCACCAGTGCATGTGCGGGAACACACACGTGCACCCTGAGCATGCTGGCCGGATCCAGAGCATCTGGTCC
CGGCTGCAGGAGACAGGCCTGCTTAGCAAGTGCGAGCGGATCCGAGGTCGCAAAGCCACGCTAGATGAGATCCAGACAGTGCACTCTGAA
TACCACACCCTGCTCTATGGGACCAGTCCCCTCAACCGGCAGAAGCTAGACAGCAAGAAGTTGCTCGGCCCCATCAGCCAGAAGATGTAT
GCTGTGCTGCCTTGTGGGGGCATCGGGGTGGACAGTGACACCGTGTGGAATGAGATGCACTCCTCCAGTGCTGTGCGCATGGCAGTGGGC
TGCCTGCTGGAGCTGGCCTTCAAGGTGGCTGCAGGAGAGCTCAAGAATGGATTTGCCATCATCCGGCCCCCAGGACACCACGCCGAGGAA
TCCACAGCCATGGGATTCTGCTTCTTCAACTCTGTAGCCATCACCGCAAAACTCCTACAGCAGAAGTTGAACGTGGGCAAGGTCCTCATC
GTGGACTGGGACATTCACCATGGCAATGGCACCCAGCAGGCGTTCTACAATGACCCCTCTGTGCTCTACATCTCTCTGCATCGCTATGAC
AACGGGAACTTCTTTCCAGGCTCTGGGGCTCCTGAAGAGGTTGGTGGAGGACCAGGCGTGGGGTACAATGTGAACGTGGCATGGACAGGA
GGTGTGGACCCCCCCATTGGAGACGTGGAGTACCTTACAGCCTTCAGGACAGTGGTGATGCCCATTGCCCACGAGTTCTCACCTGATGTG
GTCCTAGTCTCCGCCGGGTTTGATGCTGTTGAAGGACATCTGTCTCCTCTGGGTGGCTACTCTGTCACCGCCAGATGTTTTGGCCACTTG
ACCAGGCAGCTGATGACCCTGGCAGGGGGCCGGGTGGTGCTGGCCCTGGAGGGAGGCCATGACTTGACCGCCATCTGTGATGCCTCTGAG
GCTTGTGTCTCGGCTCTGCTCAGTGTAGAGCTGCAGCCCTTGGATGAGGCAGTCTTGCAGCAAAAGCCCAACATCAACGCAGTGGCCACG
CTAGAGAAAGTCATCGAGATCCAGAGCAAACACTGGAGCTGTGTGCAGAAGTTCGCCGCTGGTCTGGGCCGGTCCCTGCGAGAGGCCCAA
GCAGGTGAGACCGAGGAGGCCGAGACTGTGAGCGCCATGGCCTTGCTGTCGGTGGGGGCCGAGCAGGCCCAGGCTGCGGCAGCCCGGGAA
CACAGCCCCAGGCCGGCAGAGGAGCCCATGGAGCAGGAGCCTGCCCTGTGACGCCCCGGCCCCCATCCCTCTGGGCTTCACCATTGTGAT
TTTGTTTATTTTTTCTATTAAAAACAAAAAGTCACACATTCAACAAGGTGTGCCGTGTGGGTCTCTCAGCCTTGCCCCTCCTGCTCCTCT
ACGCTGCCTCAGGCCCCCAGCCCTGTGGCTTCCACCTCAGCTCTAGAAGCCTGCTCCCTCTGCAGGGGGTGGTGGTGTCTTCCCAGCCCT
GTCCCATGTGTCCCTCCCCCCATTTTCCTGCATTCTGTCTGTCCTTTTCCTCCTTGGAGCCTGGGCCAGCTCAAGGTGGGCACGGGGGCC
CAGACAGTACTCTCCAGTTCTGGGGCCCCCCGAGTGAGGAGGGAACGGGAAGTCGGTGCCTTGGTTTCAGCTGATTTGGGGGGAAATGCC
TTAATTTCACTCTCCTCCCTTCTCCAGCCTCAGGGGAGGATCTGGAGGATCCACTACTGTCTTTAAGATGCAGAGTGGAGGGGAGGTGGG
CACCCACCCTGCGATTCTCCACCCTTTCCCCTTCTTTCGTCCTCACCATCTCTGCAGACCCCTCTCCTCCTCCTTCCTCTTGGTCTCAGC
ACTGATGGGAGGCTGGTGCCCAAGCTGTGGCCTGCAGTCTGTGAGGAGGGCTGTCTTGCCTCACACTCCTCACAGCCTACTTCCCCTTCC
CCGGGGCTGAGAGGGTGAAAGTGTGTGGGGAAGGAGAGGACTGGTTTCCTGGGTTCTCAGGGGCCAGGAGGAGTAACAGAACCAGGTCTG
CTCCCCACCTTACTCGGATGGCCTCCCTGCCCCTCTGCTGGCACAGCCTGGGCAAGGGGAGAAGGTGGTCCCTGCAGAGGGGCTCCAGGC
TGGTGAGAGCCCCCCTGCTGTCAGGACCAGATTTTCCCAGCCATCCAGCATGCTGCGGGGAGAAGGGGCAGAGGCTCACCTCCCTCCTGG
GGCCTTTTGTTTTGGATCCTGGGGATGGTGAGAATGGAGGTTCTAGAAGGGGTAAGGCCAGAACCCAGGGATCCAGGAGTCGGCTCTCAG
CTGGAGCTTCCATACCTTCTGGGCTCCCTTTGCTGACCACCAGCCCAAGGGAGCTAAGACCAGGAGGGGGCTGGGCGCTGTCCCTTCTCT
TTCCCAGGAGCCCTGCCAGGGGCTGTGGGCCTACAAGGCTTCCAGGGGATGCCATCCAGCCTGTAGGAAACCAAAGATGGGAAGTGGCTC
CTAGGGGGCTGACTCTTCCTTCCTCCTCCTCCCCAGTACCACATATACTTTCTCTCCTTCTATCTCCAGGGCCCCACCAATCTGTTTACA
TATTTATTATCCTATGGGGGCCTGAGCAGGATTGAGGGAGCCAGGGGAGGGGCAGGAGTCCCAGCACCATCGGTTCATAGTGTGCTTGTG
TGTTTGTTTTAGATCCTCCTGGGGGATGGGGATGGGGCCAGGCTCAGTGTACTAGGCCTCTCTGTGCTGAGCCCCAGGCTCCCGGCCCCT
TACCCACTCTCTCCCTGTGGCTGGTCTGGTTCTCATGTAAACCCACTCCTTGCTTTGTCTCCCTGGATATGGATTTCAGTTAAGTATTTT

>In-frame_ENST00000376520_ENST00000225983_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(amino acids)=850AA_start in transcript=828_stop in transcript=3380
MIRDLSKMYPQTRHPAPHQPAQPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQAEIVKR
LNAICAQVIPFLSQEHQQQVVQAVERAKQVTMAELNAIIGQQLQAQHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQS
HLPIKDEKKHHDNDHQRERDKLNHKSLSPSASFRGAEKHRNSADYSSESKKQKTEEKEIAARYDSDGEKSDDNLVVDVSNEILTKTGELP
RQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSD
AQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETG
LLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELA
FKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFP
GSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMT
LAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEE

--------------------------------------------------------------
>In-frame_ENST00000376520_ENST00000393622_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(transcript)=5004nt_BP=1611nt
ACAGAGCGTGTTGTTAGAGCTGTGCTGAGCGGGTGTTTGGGTTGTTGGCTGCTTTCTTCCCCCTTTCTCACACACTTGTATATTATTTTG
AGGTGGTGTTCGCAGAGTTTGAAAGGAGAGAGAATTAAAAAAAAAAGCCGCAAGCGTTTCACTCTTTTATTTTTATAATCCCCTTCAATT
TGGGGTTAAAAAAAAGACAAGAAAACAGGAAGGAAGAGAAATAAGGAAATGAGATGTGGTAAAAGAAGCTAAAAGGTGCCTTTTAAAAGA
TCGTTGCTGTGAAGTGAAAAAAATCTCCAGAGAAACCAAAAAGCACCGCCGAGACCTCTTCCGAACCAAAGGAGTTTGTGTTTGCTTTTA
GGGAAGAAGAAAGATCATTCATTCGGAGGAATAACAACCAATTAAAAGACAAATAAAAAAAGTTTGGAGTGGGACGCAGAGCGAGCGAGA
GGAGCTGCCGGCGGGCGGTGGGGCGCGGAGCCCGCACTTTCCCGGCCGGGTGAGCGGCGGCCGCGGCGCCGGGCTCGGCGGGTGCGCCTC
GGCGGAGCGAACGTCGGAGCGTTGCCTTGGGAGACGCGCGCCGGACAATGCCCGCGGCGGGCCAGTGACGCCCGCGGGGAATGCGGAGCG
GCCCGGCAGCCGGCACCCAGCCGCCGCCGCGCGTTCCTGCCGCCCGTGTCACGCGAGACCCGGCGGGGGCCGGGACCGCCCGAGCCGCCC
CTCAGACCGAGCCGGCCGCCTCCGCTGCCGCGGCCGCCTCCTCTTCGGGGTCATTAAAGCCAATGAGCCGCGCGCCTCTGCCGAGCGCAG
CCAACTAAATCGGCTTGGATGATTCGCGACCTGAGCAAGATGTACCCGCAGACCAGACACCCAGCACCGCATCAGCCTGCTCAACCCTTT
AAATTTACAATTTCCGAATCCTGTGATCGGATTAAGGAAGAGTTTCAGTTTTTACAGGCTCAATACCACAGTCTGAAGCTGGAATGTGAG
AAACTCGCCAGTGAGAAGACAGAGATGCAGCGGCATTATGTCATGTATTATGAAATGTCCTATGGGTTGAATATAGAAATGCACAAGCAG
GCAGAGATTGTCAAGAGGCTGAATGCTATCTGTGCACAAGTCATTCCTTTCCTGTCCCAAGAGCACCAGCAACAAGTGGTGCAGGCTGTG
GAACGGGCCAAGCAGGTGACCATGGCAGAACTGAACGCCATCATTGGGCAACAACTCCAGGCCCAGCATTTATCACATGGACATGGTCTC
CCCGTACCTCTGACTCCACACCCTTCAGGGCTCCAGCCCCCTGCCATTCCACCCATCGGTAGCAGTGCCGGGCTTCTGGCCCTCTCCAGT
GCTCTAGGAGGTCAGTCCCATCTTCCAATTAAAGATGAGAAGAAGCACCATGACAATGATCACCAAAGAGAGAGAGACAAACTCAACCAC
AAAAGTTTATCCCCATCAGCCAGTTTCCGAGGTGCTGAGAAGCACAGAAACTCCGCAGACTACTCCTCAGAGAGCAAAAAGCAGAAAACT
GAAGAAAAGGAAATTGCAGCTCGTTATGACAGCGATGGTGAGAAAAGTGATGACAACTTGGTGGTTGACGTTTCCAATGAGATCCTCACC
AAGACAGGGGAGCTGCCCAGGCAGCCCACCACCCACCCTGAGGAGACAGAGGAGGAGCTGACGGAGCAGCAGGAGGTCTTGCTGGGGGAG
GGAGCCCTGACCATGCCCCGGGAGGGCTCCACAGAGAGTGAGAGCACACAGGAAGACCTGGAGGAGGAGGACGAGGAAGACGATGGGGAG
GAGGAGGAGGATTGCATCCAGGTTAAGGACGAGGAGGGCGAGAGTGGTGCTGAGGAGGGGCCCGACTTGGAGGAGCCTGGTGCTGGATAC
AAAAAACTGTTCTCAGATGCCCAGCCGCTGCAGCCTTTGCAGGTGTACCAGGCGCCCCTCAGCCTGGCCACTGTGCCCCACCAGGCCCTG
GGCCGTACCCAGTCCTCCCCTGCTGCCCCTGGGGGCATGAAGAGCCCCCCAGACCAGCCCGTCAAGCACCTCTTCACCACAGGTGTGGTC
TACGACACGTTCATGCTAAAGCACCAGTGCATGTGCGGGAACACACACGTGCACCCTGAGCATGCTGGCCGGATCCAGAGCATCTGGTCC
CGGCTGCAGGAGACAGGCCTGCTTAGCAAGTGCGAGCGGATCCGAGGTCGCAAAGCCACGCTAGATGAGATCCAGACAGTGCACTCTGAA
TACCACACCCTGCTCTATGGGACCAGTCCCCTCAACCGGCAGAAGCTAGACAGCAAGAAGTTGCTCGGCCCCATCAGCCAGAAGATGTAT
GCTGTGCTGCCTTGTGGGGGCATCGGGGTGGACAGTGACACCGTGTGGAATGAGATGCACTCCTCCAGTGCTGTGCGCATGGCAGTGGGC
TGCCTGCTGGAGCTGGCCTTCAAGGTGGCTGCAGGAGAGCTCAAGAATGGATTTGCCATCATCCGGCCCCCAGGACACCACGCCGAGGAA
TCCACAGCCATGGGATTCTGCTTCTTCAACTCTGTAGCCATCACCGCAAAACTCCTACAGCAGAAGTTGAACGTGGGCAAGGTCCTCATC
GTGGACTGGGACATTCACCATGGCAATGGCACCCAGCAGGCGTTCTACAATGACCCCTCTGTGCTCTACATCTCTCTGCATCGCTATGAC
AACGGGAACTTCTTTCCAGGCTCTGGGGCTCCTGAAGAGGTTGGTGGAGGACCAGGCGTGGGGTACAATGTGAACGTGGCATGGACAGGA
GGTGTGGACCCCCCCATTGGAGACGTGGAGTACCTTACAGCCTTCAGGACAGTGGTGATGCCCATTGCCCACGAGTTCTCACCTGATGTG
GTCCTAGTCTCCGCCGGGTTTGATGCTGTTGAAGGACATCTGTCTCCTCTGGGTGGCTACTCTGTCACCGCCAGATGTTTTGGCCACTTG
ACCAGGCAGCTGATGACCCTGGCAGGGGGCCGGGTGGTGCTGGCCCTGGAGGGAGGCCATGACTTGACCGCCATCTGTGATGCCTCTGAG
GCTTGTGTCTCGGCTCTGCTCAGTGTAGAGCTGCAGCCCTTGGATGAGGCAGTCTTGCAGCAAAAGCCCAACATCAACGCAGTGGCCACG
CTAGAGAAAGTCATCGAGATCCAGAGCAAACACTGGAGCTGTGTGCAGAAGTTCGCCGCTGGTCTGGGCCGGTCCCTGCGAGAGGCCCAA
GCAGGTGAGACCGAGGAGGCCGAGACTGTGAGCGCCATGGCCTTGCTGTCGGTGGGGGCCGAGCAGGCCCAGGCTGCGGCAGCCCGGGAA
CACAGCCCCAGGCCGGCAGAGGAGCCCATGGAGCAGGAGCCTGCCCTGTGACGCCCCGGCCCCCATCCCTCTGGGCTTCACCATTGTGAT
TTTGTTTATTTTTTCTATTAAAAACAAAAAGTCACACATTCAACAAGGTGTGCCGTGTGGGTCTCTCAGCCTTGCCCCTCCTGCTCCTCT
ACGCTGCCTCAGGCCCCCAGCCCTGTGGCTTCCACCTCAGCTCTAGAAGCCTGCTCCCTCTGCAGGGGGTGGTGGTGTCTTCCCAGCCCT
GTCCCATGTGTCCCTCCCCCCATTTTCCTGCATTCTGTCTGTCCTTTTCCTCCTTGGAGCCTGGGCCAGCTCAAGGTGGGCACGGGGGCC
CAGACAGTACTCTCCAGTTCTGGGGCCCCCCGAGTGAGGAGGGAACGGGAAGTCGGTGCCTTGGTTTCAGCTGATTTGGGGGGAAATGCC
TTAATTTCACTCTCCTCCCTTCTCCAGCCTCAGGGGAGGATCTGGAGGATCCACTACTGTCTTTAAGATGCAGAGTGGAGGGGAGGTGGG
CACCCACCCTGCGATTCTCCACCCTTTCCCCTTCTTTCGTCCTCACCATCTCTGCAGACCCCTCTCCTCCTCCTTCCTCTTGGTCTCAGC
ACTGATGGGAGGCTGGTGCCCAAGCTGTGGCCTGCAGTCTGTGAGGAGGGCTGTCTTGCCTCACACTCCTCACAGCCTACTTCCCCTTCC
CCGGGGCTGAGAGGGTGAAAGTGTGTGGGGAAGGAGAGGACTGGTTTCCTGGGTTCTCAGGGGCCAGGAGGAGTAACAGAACCAGGTCTG
CTCCCCACCTTACTCGGATGGCCTCCCTGCCCCTCTGCTGGCACAGCCTGGGCAAGGGGAGAAGGTGGTCCCTGCAGAGGGGCTCCAGGC
TGGTGAGAGCCCCCCTGCTGTCAGGACCAGATTTTCCCAGCCATCCAGCATGCTGCGGGGAGAAGGGGCAGAGGCTCACCTCCCTCCTGG
GGCCTTTTGTTTTGGATCCTGGGGATGGTGAGAATGGAGGTTCTAGAAGGGGTAAGGCCAGAACCCAGGGATCCAGGAGTCGGCTCTCAG
CTGGAGCTTCCATACCTTCTGGGCTCCCTTTGCTGACCACCAGCCCAAGGGAGCTAAGACCAGGAGGGGGCTGGGCGCTGTCCCTTCTCT
TTCCCAGGAGCCCTGCCAGGGGCTGTGGGCCTACAAGGCTTCCAGGGGATGCCATCCAGCCTGTAGGAAACCAAAGATGGGAAGTGGCTC
CTAGGGGGCTGACTCTTCCTTCCTCCTCCTCCCCAGTACCACATATACTTTCTCTCCTTCTATCTCCAGGGCCCCACCAATCTGTTTACA
TATTTATTATCCTATGGGGGCCTGAGCAGGATTGAGGGAGCCAGGGGAGGGGCAGGAGTCCCAGCACCATCGGTTCATAGTGTGCTTGTG
TGTTTGTTTTAGATCCTCCTGGGGGATGGGGATGGGGCCAGGCTCAGTGTACTAGGCCTCTCTGTGCTGAGCCCCAGGCTCCCGGCCCCT
TACCCACTCTCTCCCTGTGGCTGGTCTGGTTCTCATGTAAACCCACTCCTTGCTTTGTCTCCCTGGATATGGATTTCAGTTAAGTATTTT

>In-frame_ENST00000376520_ENST00000393622_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(amino acids)=850AA_start in transcript=828_stop in transcript=3380
MIRDLSKMYPQTRHPAPHQPAQPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQAEIVKR
LNAICAQVIPFLSQEHQQQVVQAVERAKQVTMAELNAIIGQQLQAQHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQS
HLPIKDEKKHHDNDHQRERDKLNHKSLSPSASFRGAEKHRNSADYSSESKKQKTEEKEIAARYDSDGEKSDDNLVVDVSNEILTKTGELP
RQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSD
AQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETG
LLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELA
FKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFP
GSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMT
LAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEE

--------------------------------------------------------------
>In-frame_ENST00000376520_ENST00000336057_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(transcript)=4748nt_BP=1611nt
ACAGAGCGTGTTGTTAGAGCTGTGCTGAGCGGGTGTTTGGGTTGTTGGCTGCTTTCTTCCCCCTTTCTCACACACTTGTATATTATTTTG
AGGTGGTGTTCGCAGAGTTTGAAAGGAGAGAGAATTAAAAAAAAAAGCCGCAAGCGTTTCACTCTTTTATTTTTATAATCCCCTTCAATT
TGGGGTTAAAAAAAAGACAAGAAAACAGGAAGGAAGAGAAATAAGGAAATGAGATGTGGTAAAAGAAGCTAAAAGGTGCCTTTTAAAAGA
TCGTTGCTGTGAAGTGAAAAAAATCTCCAGAGAAACCAAAAAGCACCGCCGAGACCTCTTCCGAACCAAAGGAGTTTGTGTTTGCTTTTA
GGGAAGAAGAAAGATCATTCATTCGGAGGAATAACAACCAATTAAAAGACAAATAAAAAAAGTTTGGAGTGGGACGCAGAGCGAGCGAGA
GGAGCTGCCGGCGGGCGGTGGGGCGCGGAGCCCGCACTTTCCCGGCCGGGTGAGCGGCGGCCGCGGCGCCGGGCTCGGCGGGTGCGCCTC
GGCGGAGCGAACGTCGGAGCGTTGCCTTGGGAGACGCGCGCCGGACAATGCCCGCGGCGGGCCAGTGACGCCCGCGGGGAATGCGGAGCG
GCCCGGCAGCCGGCACCCAGCCGCCGCCGCGCGTTCCTGCCGCCCGTGTCACGCGAGACCCGGCGGGGGCCGGGACCGCCCGAGCCGCCC
CTCAGACCGAGCCGGCCGCCTCCGCTGCCGCGGCCGCCTCCTCTTCGGGGTCATTAAAGCCAATGAGCCGCGCGCCTCTGCCGAGCGCAG
CCAACTAAATCGGCTTGGATGATTCGCGACCTGAGCAAGATGTACCCGCAGACCAGACACCCAGCACCGCATCAGCCTGCTCAACCCTTT
AAATTTACAATTTCCGAATCCTGTGATCGGATTAAGGAAGAGTTTCAGTTTTTACAGGCTCAATACCACAGTCTGAAGCTGGAATGTGAG
AAACTCGCCAGTGAGAAGACAGAGATGCAGCGGCATTATGTCATGTATTATGAAATGTCCTATGGGTTGAATATAGAAATGCACAAGCAG
GCAGAGATTGTCAAGAGGCTGAATGCTATCTGTGCACAAGTCATTCCTTTCCTGTCCCAAGAGCACCAGCAACAAGTGGTGCAGGCTGTG
GAACGGGCCAAGCAGGTGACCATGGCAGAACTGAACGCCATCATTGGGCAACAACTCCAGGCCCAGCATTTATCACATGGACATGGTCTC
CCCGTACCTCTGACTCCACACCCTTCAGGGCTCCAGCCCCCTGCCATTCCACCCATCGGTAGCAGTGCCGGGCTTCTGGCCCTCTCCAGT
GCTCTAGGAGGTCAGTCCCATCTTCCAATTAAAGATGAGAAGAAGCACCATGACAATGATCACCAAAGAGAGAGAGACAAACTCAACCAC
AAAAGTTTATCCCCATCAGCCAGTTTCCGAGGTGCTGAGAAGCACAGAAACTCCGCAGACTACTCCTCAGAGAGCAAAAAGCAGAAAACT
GAAGAAAAGGAAATTGCAGCTCGTTATGACAGCGATGGTGAGAAAAGTGATGACAACTTGGTGGTTGACGTTTCCAATGAGATCCTCACC
AAGACAGGGGAGCTGCCCAGGCAGCCCACCACCCACCCTGAGGAGACAGAGGAGGAGCTGACGGAGCAGCAGGAGGTCTTGCTGGGGGAG
GGAGCCCTGACCATGCCCCGGGAGGGCTCCACAGAGAGTGAGAGCACACAGGAAGACCTGGAGGAGGAGGACGAGGAAGACGATGGGGAG
GAGGAGGAGGATTGCATCCAGGTTAAGGACGAGGAGGGCGAGAGTGGTGCTGAGGAGGGGCCCGACTTGGAGGAGCCTGGTGCTGGATAC
AAAAAACTGTTCTCAGATGCCCAGCCGCTGCAGCCTTTGCAGGTGTACCAGGCGCCCCTCAGCCTGGCCACTGTGCCCCACCAGGCCCTG
GGCCGTACCCAGTCCTCCCCTGCTGCCCCTGGGGGCATGAAGAGCCCCCCAGACCAGCCCGTCAAGCACCTCTTCACCACAGGCCCCATC
AGCCAGAAGATGTATGCTGTGCTGCCTTGTGGGGGCATCGGGGTGGACAGTGACACCGTGTGGAATGAGATGCACTCCTCCAGTGCTGTG
CGCATGGCAGTGGGCTGCCTGCTGGAGCTGGCCTTCAAGGTGGCTGCAGGAGAGCTCAAGAATGGATTTGCCATCATCCGGCCCCCAGGA
CACCACGCCGAGGAATCCACAGCCATGGGATTCTGCTTCTTCAACTCTGTAGCCATCACCGCAAAACTCCTACAGCAGAAGTTGAACGTG
GGCAAGGTCCTCATCGTGGACTGGGACATTCACCATGGCAATGGCACCCAGCAGGCGTTCTACAATGACCCCTCTGTGCTCTACATCTCT
CTGCATCGCTATGACAACGGGAACTTCTTTCCAGGCTCTGGGGCTCCTGAAGAGGTTGGTGGAGGACCAGGCGTGGGGTACAATGTGAAC
GTGGCATGGACAGGAGGTGTGGACCCCCCCATTGGAGACGTGGAGTACCTTACAGCCTTCAGGACAGTGGTGATGCCCATTGCCCACGAG
TTCTCACCTGATGTGGTCCTAGTCTCCGCCGGGTTTGATGCTGTTGAAGGACATCTGTCTCCTCTGGGTGGCTACTCTGTCACCGCCAGA
TGTTTTGGCCACTTGACCAGGCAGCTGATGACCCTGGCAGGGGGCCGGGTGGTGCTGGCCCTGGAGGGAGGCCATGACTTGACCGCCATC
TGTGATGCCTCTGAGGCTTGTGTCTCGGCTCTGCTCAGTGTAGAGCTGCAGCCCTTGGATGAGGCAGTCTTGCAGCAAAAGCCCAACATC
AACGCAGTGGCCACGCTAGAGAAAGTCATCGAGATCCAGAGCAAACACTGGAGCTGTGTGCAGAAGTTCGCCGCTGGTCTGGGCCGGTCC
CTGCGAGAGGCCCAAGCAGGTGAGACCGAGGAGGCCGAGACTGTGAGCGCCATGGCCTTGCTGTCGGTGGGGGCCGAGCAGGCCCAGGCT
GCGGCAGCCCGGGAACACAGCCCCAGGCCGGCAGAGGAGCCCATGGAGCAGGAGCCTGCCCTGTGACGCCCCGGCCCCCATCCCTCTGGG
CTTCACCATTGTGATTTTGTTTATTTTTTCTATTAAAAACAAAAAGTCACACATTCAACAAGGTGTGCCGTGTGGGTCTCTCAGCCTTGC
CCCTCCTGCTCCTCTACGCTGCCTCAGGCCCCCAGCCCTGTGGCTTCCACCTCAGCTCTAGAAGCCTGCTCCCTCTGCAGGGGGTGGTGG
TGTCTTCCCAGCCCTGTCCCATGTGTCCCTCCCCCCATTTTCCTGCATTCTGTCTGTCCTTTTCCTCCTTGGAGCCTGGGCCAGCTCAAG
GTGGGCACGGGGGCCCAGACAGTACTCTCCAGTTCTGGGGCCCCCCGAGTGAGGAGGGAACGGGAAGTCGGTGCCTTGGTTTCAGCTGAT
TTGGGGGGAAATGCCTTAATTTCACTCTCCTCCCTTCTCCAGCCTCAGGGGAGGATCTGGAGGATCCACTACTGTCTTTAAGATGCAGAG
TGGAGGGGAGGTGGGCACCCACCCTGCGATTCTCCACCCTTTCCCCTTCTTTCGTCCTCACCATCTCTGCAGACCCCTCTCCTCCTCCTT
CCTCTTGGTCTCAGCACTGATGGGAGGCTGGTGCCCAAGCTGTGGCCTGCAGTCTGTGAGGAGGGCTGTCTTGCCTCACACTCCTCACAG
CCTACTTCCCCTTCCCCGGGGCTGAGAGGGTGAAAGTGTGTGGGGAAGGAGAGGACTGGTTTCCTGGGTTCTCAGGGGCCAGGAGGAGTA
ACAGAACCAGGTCTGCTCCCCACCTTACTCGGATGGCCTCCCTGCCCCTCTGCTGGCACAGCCTGGGCAAGGGGAGAAGGTGGTCCCTGC
AGAGGGGCTCCAGGCTGGTGAGAGCCCCCCTGCTGTCAGGACCAGATTTTCCCAGCCATCCAGCATGCTGCGGGGAGAAGGGGCAGAGGC
TCACCTCCCTCCTGGGGCCTTTTGTTTTGGATCCTGGGGATGGTGAGAATGGAGGTTCTAGAAGGGGTAAGGCCAGAACCCAGGGATCCA
GGAGTCGGCTCTCAGCTGGAGCTTCCATACCTTCTGGGCTCCCTTTGCTGACCACCAGCCCAAGGGAGCTAAGACCAGGAGGGGGCTGGG
CGCTGTCCCTTCTCTTTCCCAGGAGCCCTGCCAGGGGCTGTGGGCCTACAAGGCTTCCAGGGGATGCCATCCAGCCTGTAGGAAACCAAA
GATGGGAAGTGGCTCCTAGGGGGCTGACTCTTCCTTCCTCCTCCTCCCCAGTACCACATATACTTTCTCTCCTTCTATCTCCAGGGCCCC
ACCAATCTGTTTACATATTTATTATCCTATGGGGGCCTGAGCAGGATTGAGGGAGCCAGGGGAGGGGCAGGAGTCCCAGCACCATCGGTT
CATAGTGTGCTTGTGTGTTTGTTTTAGATCCTCCTGGGGGATGGGGATGGGGCCAGGCTCAGTGTACTAGGCCTCTCTGTGCTGAGCCCC
AGGCTCCCGGCCCCTTACCCACTCTCTCCCTGTGGCTGGTCTGGTTCTCATGTAAACCCACTCCTTGCTTTGTCTCCCTGGATATGGATT

>In-frame_ENST00000376520_ENST00000336057_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(amino acids)=765AA_start in transcript=828_stop in transcript=3125
MIRDLSKMYPQTRHPAPHQPAQPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQAEIVKR
LNAICAQVIPFLSQEHQQQVVQAVERAKQVTMAELNAIIGQQLQAQHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQS
HLPIKDEKKHHDNDHQRERDKLNHKSLSPSASFRGAEKHRNSADYSSESKKQKTEEKEIAARYDSDGEKSDDNLVVDVSNEILTKTGELP
RQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSD
AQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLFTTGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGC
LLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDN
GNFFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLT
RQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQA

--------------------------------------------------------------
>In-frame_ENST00000376520_ENST00000586802_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(transcript)=3463nt_BP=1611nt
ACAGAGCGTGTTGTTAGAGCTGTGCTGAGCGGGTGTTTGGGTTGTTGGCTGCTTTCTTCCCCCTTTCTCACACACTTGTATATTATTTTG
AGGTGGTGTTCGCAGAGTTTGAAAGGAGAGAGAATTAAAAAAAAAAGCCGCAAGCGTTTCACTCTTTTATTTTTATAATCCCCTTCAATT
TGGGGTTAAAAAAAAGACAAGAAAACAGGAAGGAAGAGAAATAAGGAAATGAGATGTGGTAAAAGAAGCTAAAAGGTGCCTTTTAAAAGA
TCGTTGCTGTGAAGTGAAAAAAATCTCCAGAGAAACCAAAAAGCACCGCCGAGACCTCTTCCGAACCAAAGGAGTTTGTGTTTGCTTTTA
GGGAAGAAGAAAGATCATTCATTCGGAGGAATAACAACCAATTAAAAGACAAATAAAAAAAGTTTGGAGTGGGACGCAGAGCGAGCGAGA
GGAGCTGCCGGCGGGCGGTGGGGCGCGGAGCCCGCACTTTCCCGGCCGGGTGAGCGGCGGCCGCGGCGCCGGGCTCGGCGGGTGCGCCTC
GGCGGAGCGAACGTCGGAGCGTTGCCTTGGGAGACGCGCGCCGGACAATGCCCGCGGCGGGCCAGTGACGCCCGCGGGGAATGCGGAGCG
GCCCGGCAGCCGGCACCCAGCCGCCGCCGCGCGTTCCTGCCGCCCGTGTCACGCGAGACCCGGCGGGGGCCGGGACCGCCCGAGCCGCCC
CTCAGACCGAGCCGGCCGCCTCCGCTGCCGCGGCCGCCTCCTCTTCGGGGTCATTAAAGCCAATGAGCCGCGCGCCTCTGCCGAGCGCAG
CCAACTAAATCGGCTTGGATGATTCGCGACCTGAGCAAGATGTACCCGCAGACCAGACACCCAGCACCGCATCAGCCTGCTCAACCCTTT
AAATTTACAATTTCCGAATCCTGTGATCGGATTAAGGAAGAGTTTCAGTTTTTACAGGCTCAATACCACAGTCTGAAGCTGGAATGTGAG
AAACTCGCCAGTGAGAAGACAGAGATGCAGCGGCATTATGTCATGTATTATGAAATGTCCTATGGGTTGAATATAGAAATGCACAAGCAG
GCAGAGATTGTCAAGAGGCTGAATGCTATCTGTGCACAAGTCATTCCTTTCCTGTCCCAAGAGCACCAGCAACAAGTGGTGCAGGCTGTG
GAACGGGCCAAGCAGGTGACCATGGCAGAACTGAACGCCATCATTGGGCAACAACTCCAGGCCCAGCATTTATCACATGGACATGGTCTC
CCCGTACCTCTGACTCCACACCCTTCAGGGCTCCAGCCCCCTGCCATTCCACCCATCGGTAGCAGTGCCGGGCTTCTGGCCCTCTCCAGT
GCTCTAGGAGGTCAGTCCCATCTTCCAATTAAAGATGAGAAGAAGCACCATGACAATGATCACCAAAGAGAGAGAGACAAACTCAACCAC
AAAAGTTTATCCCCATCAGCCAGTTTCCGAGGTGCTGAGAAGCACAGAAACTCCGCAGACTACTCCTCAGAGAGCAAAAAGCAGAAAACT
GAAGAAAAGGAAATTGCAGCTCGTTATGACAGCGATGGTGAGAAAAGTGATGACAACTTGGTGGTTGACGTTTCCAATGAGATCCTCACC
AAGACAGGGGAGCTGCCCAGGCAGCCCACCACCCACCCTGAGGAGACAGAGGAGGAGCTGACGGAGCAGCAGGAGGTCTTGCTGGGGGAG
GGAGCCCTGACCATGCCCCGGGAGGGCTCCACAGAGAGTGAGAGCACACAGGAAGACCTGGAGGAGGAGGACGAGGAAGACGATGGGGAG
GAGGAGGAGGATTGCATCCAGGTTAAGGACGAGGAGGGCGAGAGTGGTGCTGAGGAGGGGCCCGACTTGGAGGAGCCTGGTGCTGGATAC
AAAAAACTGTTCTCAGATGCCCAGCCGCTGCAGCCTTTGCAGGTGTACCAGGCGCCCCTCAGCCTGGCCACTGTGCCCCACCAGGCCCTG
GGCCGTACCCAGTCCTCCCCTGCTGCCCCTGGGGGCATGAAGAGCCCCCCAGACCAGCCCGTCAAGCACCTCTTCACCACAGGTGTGGTC
TACGACACGTTCATGCTAAAGCACCAGTGCATGTGCGGGAACACACACGTGCACCCTGAGCATGCTGGCCGGATCCAGAGCATCTGGTCC
CGGCTGCAGGAGACAGGCCTGCTTAGCAAGTGCGAGCGGATCCGAGGTCGCAAAGCCACGCTAGATGAGATCCAGACAGTGCACTCTGAA
TACCACACCCTGCTCTATGGGACCAGTCCCCTCAACCGGCAGAAGCTAGACAGCAAGAAGTTGCTCGGCCCCATCAGCCAGAAGATGTAT
GCTGTGCTGCCTTGTGGGGGCATCGGGGTGGACAGTGACACCGTGTGGAATGAGATGCACTCCTCCAGTGCTGTGCGCATGGCAGTGGGC
TGCCTGCTGGAGCTGGCCTTCAAGGTGGCTGCAGGAGAGCTCAAGAATGGATTTGCCATCATCCGGCCCCCAGGACACCACGCCGAGGAA
TCCACAGCCATGGGATTCTGCTTCTTCAACTCTGTAGCCATCACCGCAAAACTCCTACAGCAGAAGTTGAACGTGGGCAAGGTCCTCATC
GTGGACTGGGACATTCACCATGGCAATGGCACCCAGCAGGCGTTCTACAATGACCCCTCTGTGCTCTACATCTCTCTGCATCGCTATGAC
AACGGGAACTTCTTTCCAGGCTCTGGGGCTCCTGAAGAGGTTGGTGGAGGACCAGGCGTGGGGTACAATGTGAACGTGGCATGGACAGGA
GGTGTGGACCCCCCCATTGGAGACGTGGAGTACCTTACAGCCTTCAGGACAGTGGTGATGCCCATTGCCCACGAGTTCTCACCTGATGTG
GTCCTAGTCTCCGCCGGGTTTGATGCTGTTGAAGGACATCTGTCTCCTCTGGGTGGCTACTCTGTCACCGCCAGATGTTTTGGCCACTTG
ACCAGGCAGCTGATGACCCTGGCAGGGGGCCGGGTGGTGCTGGCCCTGGAGGGAGGCCATGACTTGACCGCCATCTGTGATGCCTCTGAG
GCTTGTGTCTCGGCTCTGCTCAGTGTAGAGCTGCAGCCCTTGGATGAGGCAGTCTTGCAGCAAAAGCCCAACATCAACGCAGTGGCCACG
CTAGAGAAAGTCATCGAGATCCAGAGCAAACACTGGAGCTGTGTGCAGAAGTTCGCCGCTGGTCTGGGCCGGTCCCTGCGAGAGGCCCAA
GCAGGTGAGACCGAGGAGGCCGAGACTGTGAGCGCCATGGCCTTGCTGTCGGTGGGGGCCGAGCAGGCCCAGGCTGCGGCAGCCCGGGAA
CACAGCCCCAGGCCGGCAGAGGAGCCCATGGAGCAGGAGCCTGCCCTGTGACGCCCCGGCCCCCATCCCTCTGGGCTTCACCATTGTGAT

>In-frame_ENST00000376520_ENST00000586802_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(amino acids)=850AA_start in transcript=828_stop in transcript=3380
MIRDLSKMYPQTRHPAPHQPAQPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQAEIVKR
LNAICAQVIPFLSQEHQQQVVQAVERAKQVTMAELNAIIGQQLQAQHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQS
HLPIKDEKKHHDNDHQRERDKLNHKSLSPSASFRGAEKHRNSADYSSESKKQKTEEKEIAARYDSDGEKSDDNLVVDVSNEILTKTGELP
RQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSD
AQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETG
LLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELA
FKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFP
GSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMT
LAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEE

--------------------------------------------------------------
>In-frame_ENST00000376537_ENST00000225983_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(transcript)=4359nt_BP=959nt
GCCGCCGCGCGTTCCTGCCGCCCGTGTCACGCGAGACCCGGCGGGGGCCGGGACCGCCCGAGCCGCCCCTCAGACCGAGCCGGCCGCCTC
CGCTGCCGCGGCCGCCTCCTCTTCGGGGTCATTAAAGCCAATGAGCCGCGCGCCTCTGCCGAGCGCAGCCAACTAAATCGGCTTGGATGA
TTCGCGACCTGAGCAAGATGTACCCGCAGACCAGACACCCAGCACCGCATCAGCCTGCTCAACCCTTTAAATTTACAATTTCCGAATCCT
GTGATCGGATTAAGGAAGAGTTTCAGTTTTTACAGGCTCAATACCACAGTCTGAAGCTGGAATGTGAGAAACTCGCCAGTGAGAAGACAG
AGATGCAGCGGCATTATGTCATGTATTATGAAATGTCCTATGGGTTGAATATAGAAATGCACAAGCAGGCAGAGATTGTCAAGAGGCTGA
ATGCTATCTGTGCACAAGTCATTCCTTTCCTGTCCCAAGAGCACCAGCAACAAGTGGTGCAGGCTGTGGAACGGGCCAAGCAGGTGACCA
TGGCAGAACTGAACGCCATCATTGGGCAACAACTCCAGGCCCAGCATTTATCACATGGACATGGTCTCCCCGTACCTCTGACTCCACACC
CTTCAGGGCTCCAGCCCCCTGCCATTCCACCCATCGGTAGCAGTGCCGGGCTTCTGGCCCTCTCCAGTGCTCTAGGAGGTCAGTCCCATC
TTCCAATTAAAGATGAGAAGAAGCACCATGACAATGATCACCAAAGAGACAGAGACTCCATCAAGAGCTCTTCAGTATCCCCATCAGCCA
GTTTCCGAGGTGCTGAGAAGCACAGAAACTCCGCAGACTACTCCTCAGAGAGCAAAAAGCAGAAAACTGAAGAAAAGGAAATTGCAGCTC
GTTATGACAGCGATGGTGAGAAAAGTGATGACAACTTGGTGGTTGACGTTTCCAATGAGATCCTCACCAAGACAGGGGAGCTGCCCAGGC
AGCCCACCACCCACCCTGAGGAGACAGAGGAGGAGCTGACGGAGCAGCAGGAGGTCTTGCTGGGGGAGGGAGCCCTGACCATGCCCCGGG
AGGGCTCCACAGAGAGTGAGAGCACACAGGAAGACCTGGAGGAGGAGGACGAGGAAGACGATGGGGAGGAGGAGGAGGATTGCATCCAGG
TTAAGGACGAGGAGGGCGAGAGTGGTGCTGAGGAGGGGCCCGACTTGGAGGAGCCTGGTGCTGGATACAAAAAACTGTTCTCAGATGCCC
AGCCGCTGCAGCCTTTGCAGGTGTACCAGGCGCCCCTCAGCCTGGCCACTGTGCCCCACCAGGCCCTGGGCCGTACCCAGTCCTCCCCTG
CTGCCCCTGGGGGCATGAAGAGCCCCCCAGACCAGCCCGTCAAGCACCTCTTCACCACAGGTGTGGTCTACGACACGTTCATGCTAAAGC
ACCAGTGCATGTGCGGGAACACACACGTGCACCCTGAGCATGCTGGCCGGATCCAGAGCATCTGGTCCCGGCTGCAGGAGACAGGCCTGC
TTAGCAAGTGCGAGCGGATCCGAGGTCGCAAAGCCACGCTAGATGAGATCCAGACAGTGCACTCTGAATACCACACCCTGCTCTATGGGA
CCAGTCCCCTCAACCGGCAGAAGCTAGACAGCAAGAAGTTGCTCGGCCCCATCAGCCAGAAGATGTATGCTGTGCTGCCTTGTGGGGGCA
TCGGGGTGGACAGTGACACCGTGTGGAATGAGATGCACTCCTCCAGTGCTGTGCGCATGGCAGTGGGCTGCCTGCTGGAGCTGGCCTTCA
AGGTGGCTGCAGGAGAGCTCAAGAATGGATTTGCCATCATCCGGCCCCCAGGACACCACGCCGAGGAATCCACAGCCATGGGATTCTGCT
TCTTCAACTCTGTAGCCATCACCGCAAAACTCCTACAGCAGAAGTTGAACGTGGGCAAGGTCCTCATCGTGGACTGGGACATTCACCATG
GCAATGGCACCCAGCAGGCGTTCTACAATGACCCCTCTGTGCTCTACATCTCTCTGCATCGCTATGACAACGGGAACTTCTTTCCAGGCT
CTGGGGCTCCTGAAGAGGTTGGTGGAGGACCAGGCGTGGGGTACAATGTGAACGTGGCATGGACAGGAGGTGTGGACCCCCCCATTGGAG
ACGTGGAGTACCTTACAGCCTTCAGGACAGTGGTGATGCCCATTGCCCACGAGTTCTCACCTGATGTGGTCCTAGTCTCCGCCGGGTTTG
ATGCTGTTGAAGGACATCTGTCTCCTCTGGGTGGCTACTCTGTCACCGCCAGATGTTTTGGCCACTTGACCAGGCAGCTGATGACCCTGG
CAGGGGGCCGGGTGGTGCTGGCCCTGGAGGGAGGCCATGACTTGACCGCCATCTGTGATGCCTCTGAGGCTTGTGTCTCGGCTCTGCTCA
GTGTAGAGCTGCAGCCCTTGGATGAGGCAGTCTTGCAGCAAAAGCCCAACATCAACGCAGTGGCCACGCTAGAGAAAGTCATCGAGATCC
AGAGCAAACACTGGAGCTGTGTGCAGAAGTTCGCCGCTGGTCTGGGCCGGTCCCTGCGAGAGGCCCAAGCAGGTGAGACCGAGGAGGCCG
AGACTGTGAGCGCCATGGCCTTGCTGTCGGTGGGGGCCGAGCAGGCCCAGGCTGCGGCAGCCCGGGAACACAGCCCCAGGCCGGCAGAGG
AGCCCATGGAGCAGGAGCCTGCCCTGTGACGCCCCGGCCCCCATCCCTCTGGGCTTCACCATTGTGATTTTGTTTATTTTTTCTATTAAA
AACAAAAAGTCACACATTCAACAAGGTGTGCCGTGTGGGTCTCTCAGCCTTGCCCCTCCTGCTCCTCTACGCTGCCTCAGGCCCCCAGCC
CTGTGGCTTCCACCTCAGCTCTAGAAGCCTGCTCCCTCTGCAGGGGGTGGTGGTGTCTTCCCAGCCCTGTCCCATGTGTCCCTCCCCCCA
TTTTCCTGCATTCTGTCTGTCCTTTTCCTCCTTGGAGCCTGGGCCAGCTCAAGGTGGGCACGGGGGCCCAGACAGTACTCTCCAGTTCTG
GGGCCCCCCGAGTGAGGAGGGAACGGGAAGTCGGTGCCTTGGTTTCAGCTGATTTGGGGGGAAATGCCTTAATTTCACTCTCCTCCCTTC
TCCAGCCTCAGGGGAGGATCTGGAGGATCCACTACTGTCTTTAAGATGCAGAGTGGAGGGGAGGTGGGCACCCACCCTGCGATTCTCCAC
CCTTTCCCCTTCTTTCGTCCTCACCATCTCTGCAGACCCCTCTCCTCCTCCTTCCTCTTGGTCTCAGCACTGATGGGAGGCTGGTGCCCA
AGCTGTGGCCTGCAGTCTGTGAGGAGGGCTGTCTTGCCTCACACTCCTCACAGCCTACTTCCCCTTCCCCGGGGCTGAGAGGGTGAAAGT
GTGTGGGGAAGGAGAGGACTGGTTTCCTGGGTTCTCAGGGGCCAGGAGGAGTAACAGAACCAGGTCTGCTCCCCACCTTACTCGGATGGC
CTCCCTGCCCCTCTGCTGGCACAGCCTGGGCAAGGGGAGAAGGTGGTCCCTGCAGAGGGGCTCCAGGCTGGTGAGAGCCCCCCTGCTGTC
AGGACCAGATTTTCCCAGCCATCCAGCATGCTGCGGGGAGAAGGGGCAGAGGCTCACCTCCCTCCTGGGGCCTTTTGTTTTGGATCCTGG
GGATGGTGAGAATGGAGGTTCTAGAAGGGGTAAGGCCAGAACCCAGGGATCCAGGAGTCGGCTCTCAGCTGGAGCTTCCATACCTTCTGG
GCTCCCTTTGCTGACCACCAGCCCAAGGGAGCTAAGACCAGGAGGGGGCTGGGCGCTGTCCCTTCTCTTTCCCAGGAGCCCTGCCAGGGG
CTGTGGGCCTACAAGGCTTCCAGGGGATGCCATCCAGCCTGTAGGAAACCAAAGATGGGAAGTGGCTCCTAGGGGGCTGACTCTTCCTTC
CTCCTCCTCCCCAGTACCACATATACTTTCTCTCCTTCTATCTCCAGGGCCCCACCAATCTGTTTACATATTTATTATCCTATGGGGGCC
TGAGCAGGATTGAGGGAGCCAGGGGAGGGGCAGGAGTCCCAGCACCATCGGTTCATAGTGTGCTTGTGTGTTTGTTTTAGATCCTCCTGG
GGGATGGGGATGGGGCCAGGCTCAGTGTACTAGGCCTCTCTGTGCTGAGCCCCAGGCTCCCGGCCCCTTACCCACTCTCTCCCTGTGGCT
GGTCTGGTTCTCATGTAAACCCACTCCTTGCTTTGTCTCCCTGGATATGGATTTCAGTTAAGTATTTTGTAACCCGTTACACTGTGTGTC

>In-frame_ENST00000376537_ENST00000225983_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(amino acids)=850AA_start in transcript=176_stop in transcript=2728
MIRDLSKMYPQTRHPAPHQPAQPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQAEIVKR
LNAICAQVIPFLSQEHQQQVVQAVERAKQVTMAELNAIIGQQLQAQHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQS
HLPIKDEKKHHDNDHQRDRDSIKSSSVSPSASFRGAEKHRNSADYSSESKKQKTEEKEIAARYDSDGEKSDDNLVVDVSNEILTKTGELP
RQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSD
AQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETG
LLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELA
FKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFP
GSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMT
LAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEE

--------------------------------------------------------------
>In-frame_ENST00000376537_ENST00000393622_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(transcript)=4352nt_BP=959nt
GCCGCCGCGCGTTCCTGCCGCCCGTGTCACGCGAGACCCGGCGGGGGCCGGGACCGCCCGAGCCGCCCCTCAGACCGAGCCGGCCGCCTC
CGCTGCCGCGGCCGCCTCCTCTTCGGGGTCATTAAAGCCAATGAGCCGCGCGCCTCTGCCGAGCGCAGCCAACTAAATCGGCTTGGATGA
TTCGCGACCTGAGCAAGATGTACCCGCAGACCAGACACCCAGCACCGCATCAGCCTGCTCAACCCTTTAAATTTACAATTTCCGAATCCT
GTGATCGGATTAAGGAAGAGTTTCAGTTTTTACAGGCTCAATACCACAGTCTGAAGCTGGAATGTGAGAAACTCGCCAGTGAGAAGACAG
AGATGCAGCGGCATTATGTCATGTATTATGAAATGTCCTATGGGTTGAATATAGAAATGCACAAGCAGGCAGAGATTGTCAAGAGGCTGA
ATGCTATCTGTGCACAAGTCATTCCTTTCCTGTCCCAAGAGCACCAGCAACAAGTGGTGCAGGCTGTGGAACGGGCCAAGCAGGTGACCA
TGGCAGAACTGAACGCCATCATTGGGCAACAACTCCAGGCCCAGCATTTATCACATGGACATGGTCTCCCCGTACCTCTGACTCCACACC
CTTCAGGGCTCCAGCCCCCTGCCATTCCACCCATCGGTAGCAGTGCCGGGCTTCTGGCCCTCTCCAGTGCTCTAGGAGGTCAGTCCCATC
TTCCAATTAAAGATGAGAAGAAGCACCATGACAATGATCACCAAAGAGACAGAGACTCCATCAAGAGCTCTTCAGTATCCCCATCAGCCA
GTTTCCGAGGTGCTGAGAAGCACAGAAACTCCGCAGACTACTCCTCAGAGAGCAAAAAGCAGAAAACTGAAGAAAAGGAAATTGCAGCTC
GTTATGACAGCGATGGTGAGAAAAGTGATGACAACTTGGTGGTTGACGTTTCCAATGAGATCCTCACCAAGACAGGGGAGCTGCCCAGGC
AGCCCACCACCCACCCTGAGGAGACAGAGGAGGAGCTGACGGAGCAGCAGGAGGTCTTGCTGGGGGAGGGAGCCCTGACCATGCCCCGGG
AGGGCTCCACAGAGAGTGAGAGCACACAGGAAGACCTGGAGGAGGAGGACGAGGAAGACGATGGGGAGGAGGAGGAGGATTGCATCCAGG
TTAAGGACGAGGAGGGCGAGAGTGGTGCTGAGGAGGGGCCCGACTTGGAGGAGCCTGGTGCTGGATACAAAAAACTGTTCTCAGATGCCC
AGCCGCTGCAGCCTTTGCAGGTGTACCAGGCGCCCCTCAGCCTGGCCACTGTGCCCCACCAGGCCCTGGGCCGTACCCAGTCCTCCCCTG
CTGCCCCTGGGGGCATGAAGAGCCCCCCAGACCAGCCCGTCAAGCACCTCTTCACCACAGGTGTGGTCTACGACACGTTCATGCTAAAGC
ACCAGTGCATGTGCGGGAACACACACGTGCACCCTGAGCATGCTGGCCGGATCCAGAGCATCTGGTCCCGGCTGCAGGAGACAGGCCTGC
TTAGCAAGTGCGAGCGGATCCGAGGTCGCAAAGCCACGCTAGATGAGATCCAGACAGTGCACTCTGAATACCACACCCTGCTCTATGGGA
CCAGTCCCCTCAACCGGCAGAAGCTAGACAGCAAGAAGTTGCTCGGCCCCATCAGCCAGAAGATGTATGCTGTGCTGCCTTGTGGGGGCA
TCGGGGTGGACAGTGACACCGTGTGGAATGAGATGCACTCCTCCAGTGCTGTGCGCATGGCAGTGGGCTGCCTGCTGGAGCTGGCCTTCA
AGGTGGCTGCAGGAGAGCTCAAGAATGGATTTGCCATCATCCGGCCCCCAGGACACCACGCCGAGGAATCCACAGCCATGGGATTCTGCT
TCTTCAACTCTGTAGCCATCACCGCAAAACTCCTACAGCAGAAGTTGAACGTGGGCAAGGTCCTCATCGTGGACTGGGACATTCACCATG
GCAATGGCACCCAGCAGGCGTTCTACAATGACCCCTCTGTGCTCTACATCTCTCTGCATCGCTATGACAACGGGAACTTCTTTCCAGGCT
CTGGGGCTCCTGAAGAGGTTGGTGGAGGACCAGGCGTGGGGTACAATGTGAACGTGGCATGGACAGGAGGTGTGGACCCCCCCATTGGAG
ACGTGGAGTACCTTACAGCCTTCAGGACAGTGGTGATGCCCATTGCCCACGAGTTCTCACCTGATGTGGTCCTAGTCTCCGCCGGGTTTG
ATGCTGTTGAAGGACATCTGTCTCCTCTGGGTGGCTACTCTGTCACCGCCAGATGTTTTGGCCACTTGACCAGGCAGCTGATGACCCTGG
CAGGGGGCCGGGTGGTGCTGGCCCTGGAGGGAGGCCATGACTTGACCGCCATCTGTGATGCCTCTGAGGCTTGTGTCTCGGCTCTGCTCA
GTGTAGAGCTGCAGCCCTTGGATGAGGCAGTCTTGCAGCAAAAGCCCAACATCAACGCAGTGGCCACGCTAGAGAAAGTCATCGAGATCC
AGAGCAAACACTGGAGCTGTGTGCAGAAGTTCGCCGCTGGTCTGGGCCGGTCCCTGCGAGAGGCCCAAGCAGGTGAGACCGAGGAGGCCG
AGACTGTGAGCGCCATGGCCTTGCTGTCGGTGGGGGCCGAGCAGGCCCAGGCTGCGGCAGCCCGGGAACACAGCCCCAGGCCGGCAGAGG
AGCCCATGGAGCAGGAGCCTGCCCTGTGACGCCCCGGCCCCCATCCCTCTGGGCTTCACCATTGTGATTTTGTTTATTTTTTCTATTAAA
AACAAAAAGTCACACATTCAACAAGGTGTGCCGTGTGGGTCTCTCAGCCTTGCCCCTCCTGCTCCTCTACGCTGCCTCAGGCCCCCAGCC
CTGTGGCTTCCACCTCAGCTCTAGAAGCCTGCTCCCTCTGCAGGGGGTGGTGGTGTCTTCCCAGCCCTGTCCCATGTGTCCCTCCCCCCA
TTTTCCTGCATTCTGTCTGTCCTTTTCCTCCTTGGAGCCTGGGCCAGCTCAAGGTGGGCACGGGGGCCCAGACAGTACTCTCCAGTTCTG
GGGCCCCCCGAGTGAGGAGGGAACGGGAAGTCGGTGCCTTGGTTTCAGCTGATTTGGGGGGAAATGCCTTAATTTCACTCTCCTCCCTTC
TCCAGCCTCAGGGGAGGATCTGGAGGATCCACTACTGTCTTTAAGATGCAGAGTGGAGGGGAGGTGGGCACCCACCCTGCGATTCTCCAC
CCTTTCCCCTTCTTTCGTCCTCACCATCTCTGCAGACCCCTCTCCTCCTCCTTCCTCTTGGTCTCAGCACTGATGGGAGGCTGGTGCCCA
AGCTGTGGCCTGCAGTCTGTGAGGAGGGCTGTCTTGCCTCACACTCCTCACAGCCTACTTCCCCTTCCCCGGGGCTGAGAGGGTGAAAGT
GTGTGGGGAAGGAGAGGACTGGTTTCCTGGGTTCTCAGGGGCCAGGAGGAGTAACAGAACCAGGTCTGCTCCCCACCTTACTCGGATGGC
CTCCCTGCCCCTCTGCTGGCACAGCCTGGGCAAGGGGAGAAGGTGGTCCCTGCAGAGGGGCTCCAGGCTGGTGAGAGCCCCCCTGCTGTC
AGGACCAGATTTTCCCAGCCATCCAGCATGCTGCGGGGAGAAGGGGCAGAGGCTCACCTCCCTCCTGGGGCCTTTTGTTTTGGATCCTGG
GGATGGTGAGAATGGAGGTTCTAGAAGGGGTAAGGCCAGAACCCAGGGATCCAGGAGTCGGCTCTCAGCTGGAGCTTCCATACCTTCTGG
GCTCCCTTTGCTGACCACCAGCCCAAGGGAGCTAAGACCAGGAGGGGGCTGGGCGCTGTCCCTTCTCTTTCCCAGGAGCCCTGCCAGGGG
CTGTGGGCCTACAAGGCTTCCAGGGGATGCCATCCAGCCTGTAGGAAACCAAAGATGGGAAGTGGCTCCTAGGGGGCTGACTCTTCCTTC
CTCCTCCTCCCCAGTACCACATATACTTTCTCTCCTTCTATCTCCAGGGCCCCACCAATCTGTTTACATATTTATTATCCTATGGGGGCC
TGAGCAGGATTGAGGGAGCCAGGGGAGGGGCAGGAGTCCCAGCACCATCGGTTCATAGTGTGCTTGTGTGTTTGTTTTAGATCCTCCTGG
GGGATGGGGATGGGGCCAGGCTCAGTGTACTAGGCCTCTCTGTGCTGAGCCCCAGGCTCCCGGCCCCTTACCCACTCTCTCCCTGTGGCT
GGTCTGGTTCTCATGTAAACCCACTCCTTGCTTTGTCTCCCTGGATATGGATTTCAGTTAAGTATTTTGTAACCCGTTACACTGTGTGTC

>In-frame_ENST00000376537_ENST00000393622_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(amino acids)=850AA_start in transcript=176_stop in transcript=2728
MIRDLSKMYPQTRHPAPHQPAQPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQAEIVKR
LNAICAQVIPFLSQEHQQQVVQAVERAKQVTMAELNAIIGQQLQAQHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQS
HLPIKDEKKHHDNDHQRDRDSIKSSSVSPSASFRGAEKHRNSADYSSESKKQKTEEKEIAARYDSDGEKSDDNLVVDVSNEILTKTGELP
RQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSD
AQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETG
LLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELA
FKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFP
GSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMT
LAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEE

--------------------------------------------------------------
>In-frame_ENST00000376537_ENST00000336057_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(transcript)=4096nt_BP=959nt
GCCGCCGCGCGTTCCTGCCGCCCGTGTCACGCGAGACCCGGCGGGGGCCGGGACCGCCCGAGCCGCCCCTCAGACCGAGCCGGCCGCCTC
CGCTGCCGCGGCCGCCTCCTCTTCGGGGTCATTAAAGCCAATGAGCCGCGCGCCTCTGCCGAGCGCAGCCAACTAAATCGGCTTGGATGA
TTCGCGACCTGAGCAAGATGTACCCGCAGACCAGACACCCAGCACCGCATCAGCCTGCTCAACCCTTTAAATTTACAATTTCCGAATCCT
GTGATCGGATTAAGGAAGAGTTTCAGTTTTTACAGGCTCAATACCACAGTCTGAAGCTGGAATGTGAGAAACTCGCCAGTGAGAAGACAG
AGATGCAGCGGCATTATGTCATGTATTATGAAATGTCCTATGGGTTGAATATAGAAATGCACAAGCAGGCAGAGATTGTCAAGAGGCTGA
ATGCTATCTGTGCACAAGTCATTCCTTTCCTGTCCCAAGAGCACCAGCAACAAGTGGTGCAGGCTGTGGAACGGGCCAAGCAGGTGACCA
TGGCAGAACTGAACGCCATCATTGGGCAACAACTCCAGGCCCAGCATTTATCACATGGACATGGTCTCCCCGTACCTCTGACTCCACACC
CTTCAGGGCTCCAGCCCCCTGCCATTCCACCCATCGGTAGCAGTGCCGGGCTTCTGGCCCTCTCCAGTGCTCTAGGAGGTCAGTCCCATC
TTCCAATTAAAGATGAGAAGAAGCACCATGACAATGATCACCAAAGAGACAGAGACTCCATCAAGAGCTCTTCAGTATCCCCATCAGCCA
GTTTCCGAGGTGCTGAGAAGCACAGAAACTCCGCAGACTACTCCTCAGAGAGCAAAAAGCAGAAAACTGAAGAAAAGGAAATTGCAGCTC
GTTATGACAGCGATGGTGAGAAAAGTGATGACAACTTGGTGGTTGACGTTTCCAATGAGATCCTCACCAAGACAGGGGAGCTGCCCAGGC
AGCCCACCACCCACCCTGAGGAGACAGAGGAGGAGCTGACGGAGCAGCAGGAGGTCTTGCTGGGGGAGGGAGCCCTGACCATGCCCCGGG
AGGGCTCCACAGAGAGTGAGAGCACACAGGAAGACCTGGAGGAGGAGGACGAGGAAGACGATGGGGAGGAGGAGGAGGATTGCATCCAGG
TTAAGGACGAGGAGGGCGAGAGTGGTGCTGAGGAGGGGCCCGACTTGGAGGAGCCTGGTGCTGGATACAAAAAACTGTTCTCAGATGCCC
AGCCGCTGCAGCCTTTGCAGGTGTACCAGGCGCCCCTCAGCCTGGCCACTGTGCCCCACCAGGCCCTGGGCCGTACCCAGTCCTCCCCTG
CTGCCCCTGGGGGCATGAAGAGCCCCCCAGACCAGCCCGTCAAGCACCTCTTCACCACAGGCCCCATCAGCCAGAAGATGTATGCTGTGC
TGCCTTGTGGGGGCATCGGGGTGGACAGTGACACCGTGTGGAATGAGATGCACTCCTCCAGTGCTGTGCGCATGGCAGTGGGCTGCCTGC
TGGAGCTGGCCTTCAAGGTGGCTGCAGGAGAGCTCAAGAATGGATTTGCCATCATCCGGCCCCCAGGACACCACGCCGAGGAATCCACAG
CCATGGGATTCTGCTTCTTCAACTCTGTAGCCATCACCGCAAAACTCCTACAGCAGAAGTTGAACGTGGGCAAGGTCCTCATCGTGGACT
GGGACATTCACCATGGCAATGGCACCCAGCAGGCGTTCTACAATGACCCCTCTGTGCTCTACATCTCTCTGCATCGCTATGACAACGGGA
ACTTCTTTCCAGGCTCTGGGGCTCCTGAAGAGGTTGGTGGAGGACCAGGCGTGGGGTACAATGTGAACGTGGCATGGACAGGAGGTGTGG
ACCCCCCCATTGGAGACGTGGAGTACCTTACAGCCTTCAGGACAGTGGTGATGCCCATTGCCCACGAGTTCTCACCTGATGTGGTCCTAG
TCTCCGCCGGGTTTGATGCTGTTGAAGGACATCTGTCTCCTCTGGGTGGCTACTCTGTCACCGCCAGATGTTTTGGCCACTTGACCAGGC
AGCTGATGACCCTGGCAGGGGGCCGGGTGGTGCTGGCCCTGGAGGGAGGCCATGACTTGACCGCCATCTGTGATGCCTCTGAGGCTTGTG
TCTCGGCTCTGCTCAGTGTAGAGCTGCAGCCCTTGGATGAGGCAGTCTTGCAGCAAAAGCCCAACATCAACGCAGTGGCCACGCTAGAGA
AAGTCATCGAGATCCAGAGCAAACACTGGAGCTGTGTGCAGAAGTTCGCCGCTGGTCTGGGCCGGTCCCTGCGAGAGGCCCAAGCAGGTG
AGACCGAGGAGGCCGAGACTGTGAGCGCCATGGCCTTGCTGTCGGTGGGGGCCGAGCAGGCCCAGGCTGCGGCAGCCCGGGAACACAGCC
CCAGGCCGGCAGAGGAGCCCATGGAGCAGGAGCCTGCCCTGTGACGCCCCGGCCCCCATCCCTCTGGGCTTCACCATTGTGATTTTGTTT
ATTTTTTCTATTAAAAACAAAAAGTCACACATTCAACAAGGTGTGCCGTGTGGGTCTCTCAGCCTTGCCCCTCCTGCTCCTCTACGCTGC
CTCAGGCCCCCAGCCCTGTGGCTTCCACCTCAGCTCTAGAAGCCTGCTCCCTCTGCAGGGGGTGGTGGTGTCTTCCCAGCCCTGTCCCAT
GTGTCCCTCCCCCCATTTTCCTGCATTCTGTCTGTCCTTTTCCTCCTTGGAGCCTGGGCCAGCTCAAGGTGGGCACGGGGGCCCAGACAG
TACTCTCCAGTTCTGGGGCCCCCCGAGTGAGGAGGGAACGGGAAGTCGGTGCCTTGGTTTCAGCTGATTTGGGGGGAAATGCCTTAATTT
CACTCTCCTCCCTTCTCCAGCCTCAGGGGAGGATCTGGAGGATCCACTACTGTCTTTAAGATGCAGAGTGGAGGGGAGGTGGGCACCCAC
CCTGCGATTCTCCACCCTTTCCCCTTCTTTCGTCCTCACCATCTCTGCAGACCCCTCTCCTCCTCCTTCCTCTTGGTCTCAGCACTGATG
GGAGGCTGGTGCCCAAGCTGTGGCCTGCAGTCTGTGAGGAGGGCTGTCTTGCCTCACACTCCTCACAGCCTACTTCCCCTTCCCCGGGGC
TGAGAGGGTGAAAGTGTGTGGGGAAGGAGAGGACTGGTTTCCTGGGTTCTCAGGGGCCAGGAGGAGTAACAGAACCAGGTCTGCTCCCCA
CCTTACTCGGATGGCCTCCCTGCCCCTCTGCTGGCACAGCCTGGGCAAGGGGAGAAGGTGGTCCCTGCAGAGGGGCTCCAGGCTGGTGAG
AGCCCCCCTGCTGTCAGGACCAGATTTTCCCAGCCATCCAGCATGCTGCGGGGAGAAGGGGCAGAGGCTCACCTCCCTCCTGGGGCCTTT
TGTTTTGGATCCTGGGGATGGTGAGAATGGAGGTTCTAGAAGGGGTAAGGCCAGAACCCAGGGATCCAGGAGTCGGCTCTCAGCTGGAGC
TTCCATACCTTCTGGGCTCCCTTTGCTGACCACCAGCCCAAGGGAGCTAAGACCAGGAGGGGGCTGGGCGCTGTCCCTTCTCTTTCCCAG
GAGCCCTGCCAGGGGCTGTGGGCCTACAAGGCTTCCAGGGGATGCCATCCAGCCTGTAGGAAACCAAAGATGGGAAGTGGCTCCTAGGGG
GCTGACTCTTCCTTCCTCCTCCTCCCCAGTACCACATATACTTTCTCTCCTTCTATCTCCAGGGCCCCACCAATCTGTTTACATATTTAT
TATCCTATGGGGGCCTGAGCAGGATTGAGGGAGCCAGGGGAGGGGCAGGAGTCCCAGCACCATCGGTTCATAGTGTGCTTGTGTGTTTGT
TTTAGATCCTCCTGGGGGATGGGGATGGGGCCAGGCTCAGTGTACTAGGCCTCTCTGTGCTGAGCCCCAGGCTCCCGGCCCCTTACCCAC
TCTCTCCCTGTGGCTGGTCTGGTTCTCATGTAAACCCACTCCTTGCTTTGTCTCCCTGGATATGGATTTCAGTTAAGTATTTTGTAACCC

>In-frame_ENST00000376537_ENST00000336057_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(amino acids)=765AA_start in transcript=176_stop in transcript=2473
MIRDLSKMYPQTRHPAPHQPAQPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQAEIVKR
LNAICAQVIPFLSQEHQQQVVQAVERAKQVTMAELNAIIGQQLQAQHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQS
HLPIKDEKKHHDNDHQRDRDSIKSSSVSPSASFRGAEKHRNSADYSSESKKQKTEEKEIAARYDSDGEKSDDNLVVDVSNEILTKTGELP
RQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSD
AQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLFTTGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGC
LLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDN
GNFFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLT
RQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQA

--------------------------------------------------------------
>In-frame_ENST00000376537_ENST00000586802_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(transcript)=2811nt_BP=959nt
GCCGCCGCGCGTTCCTGCCGCCCGTGTCACGCGAGACCCGGCGGGGGCCGGGACCGCCCGAGCCGCCCCTCAGACCGAGCCGGCCGCCTC
CGCTGCCGCGGCCGCCTCCTCTTCGGGGTCATTAAAGCCAATGAGCCGCGCGCCTCTGCCGAGCGCAGCCAACTAAATCGGCTTGGATGA
TTCGCGACCTGAGCAAGATGTACCCGCAGACCAGACACCCAGCACCGCATCAGCCTGCTCAACCCTTTAAATTTACAATTTCCGAATCCT
GTGATCGGATTAAGGAAGAGTTTCAGTTTTTACAGGCTCAATACCACAGTCTGAAGCTGGAATGTGAGAAACTCGCCAGTGAGAAGACAG
AGATGCAGCGGCATTATGTCATGTATTATGAAATGTCCTATGGGTTGAATATAGAAATGCACAAGCAGGCAGAGATTGTCAAGAGGCTGA
ATGCTATCTGTGCACAAGTCATTCCTTTCCTGTCCCAAGAGCACCAGCAACAAGTGGTGCAGGCTGTGGAACGGGCCAAGCAGGTGACCA
TGGCAGAACTGAACGCCATCATTGGGCAACAACTCCAGGCCCAGCATTTATCACATGGACATGGTCTCCCCGTACCTCTGACTCCACACC
CTTCAGGGCTCCAGCCCCCTGCCATTCCACCCATCGGTAGCAGTGCCGGGCTTCTGGCCCTCTCCAGTGCTCTAGGAGGTCAGTCCCATC
TTCCAATTAAAGATGAGAAGAAGCACCATGACAATGATCACCAAAGAGACAGAGACTCCATCAAGAGCTCTTCAGTATCCCCATCAGCCA
GTTTCCGAGGTGCTGAGAAGCACAGAAACTCCGCAGACTACTCCTCAGAGAGCAAAAAGCAGAAAACTGAAGAAAAGGAAATTGCAGCTC
GTTATGACAGCGATGGTGAGAAAAGTGATGACAACTTGGTGGTTGACGTTTCCAATGAGATCCTCACCAAGACAGGGGAGCTGCCCAGGC
AGCCCACCACCCACCCTGAGGAGACAGAGGAGGAGCTGACGGAGCAGCAGGAGGTCTTGCTGGGGGAGGGAGCCCTGACCATGCCCCGGG
AGGGCTCCACAGAGAGTGAGAGCACACAGGAAGACCTGGAGGAGGAGGACGAGGAAGACGATGGGGAGGAGGAGGAGGATTGCATCCAGG
TTAAGGACGAGGAGGGCGAGAGTGGTGCTGAGGAGGGGCCCGACTTGGAGGAGCCTGGTGCTGGATACAAAAAACTGTTCTCAGATGCCC
AGCCGCTGCAGCCTTTGCAGGTGTACCAGGCGCCCCTCAGCCTGGCCACTGTGCCCCACCAGGCCCTGGGCCGTACCCAGTCCTCCCCTG
CTGCCCCTGGGGGCATGAAGAGCCCCCCAGACCAGCCCGTCAAGCACCTCTTCACCACAGGTGTGGTCTACGACACGTTCATGCTAAAGC
ACCAGTGCATGTGCGGGAACACACACGTGCACCCTGAGCATGCTGGCCGGATCCAGAGCATCTGGTCCCGGCTGCAGGAGACAGGCCTGC
TTAGCAAGTGCGAGCGGATCCGAGGTCGCAAAGCCACGCTAGATGAGATCCAGACAGTGCACTCTGAATACCACACCCTGCTCTATGGGA
CCAGTCCCCTCAACCGGCAGAAGCTAGACAGCAAGAAGTTGCTCGGCCCCATCAGCCAGAAGATGTATGCTGTGCTGCCTTGTGGGGGCA
TCGGGGTGGACAGTGACACCGTGTGGAATGAGATGCACTCCTCCAGTGCTGTGCGCATGGCAGTGGGCTGCCTGCTGGAGCTGGCCTTCA
AGGTGGCTGCAGGAGAGCTCAAGAATGGATTTGCCATCATCCGGCCCCCAGGACACCACGCCGAGGAATCCACAGCCATGGGATTCTGCT
TCTTCAACTCTGTAGCCATCACCGCAAAACTCCTACAGCAGAAGTTGAACGTGGGCAAGGTCCTCATCGTGGACTGGGACATTCACCATG
GCAATGGCACCCAGCAGGCGTTCTACAATGACCCCTCTGTGCTCTACATCTCTCTGCATCGCTATGACAACGGGAACTTCTTTCCAGGCT
CTGGGGCTCCTGAAGAGGTTGGTGGAGGACCAGGCGTGGGGTACAATGTGAACGTGGCATGGACAGGAGGTGTGGACCCCCCCATTGGAG
ACGTGGAGTACCTTACAGCCTTCAGGACAGTGGTGATGCCCATTGCCCACGAGTTCTCACCTGATGTGGTCCTAGTCTCCGCCGGGTTTG
ATGCTGTTGAAGGACATCTGTCTCCTCTGGGTGGCTACTCTGTCACCGCCAGATGTTTTGGCCACTTGACCAGGCAGCTGATGACCCTGG
CAGGGGGCCGGGTGGTGCTGGCCCTGGAGGGAGGCCATGACTTGACCGCCATCTGTGATGCCTCTGAGGCTTGTGTCTCGGCTCTGCTCA
GTGTAGAGCTGCAGCCCTTGGATGAGGCAGTCTTGCAGCAAAAGCCCAACATCAACGCAGTGGCCACGCTAGAGAAAGTCATCGAGATCC
AGAGCAAACACTGGAGCTGTGTGCAGAAGTTCGCCGCTGGTCTGGGCCGGTCCCTGCGAGAGGCCCAAGCAGGTGAGACCGAGGAGGCCG
AGACTGTGAGCGCCATGGCCTTGCTGTCGGTGGGGGCCGAGCAGGCCCAGGCTGCGGCAGCCCGGGAACACAGCCCCAGGCCGGCAGAGG
AGCCCATGGAGCAGGAGCCTGCCCTGTGACGCCCCGGCCCCCATCCCTCTGGGCTTCACCATTGTGATTTTGTTTATTTTTTCTATTAAA

>In-frame_ENST00000376537_ENST00000586802_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(amino acids)=850AA_start in transcript=176_stop in transcript=2728
MIRDLSKMYPQTRHPAPHQPAQPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQAEIVKR
LNAICAQVIPFLSQEHQQQVVQAVERAKQVTMAELNAIIGQQLQAQHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQS
HLPIKDEKKHHDNDHQRDRDSIKSSSVSPSASFRGAEKHRNSADYSSESKKQKTEEKEIAARYDSDGEKSDDNLVVDVSNEILTKTGELP
RQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSD
AQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETG
LLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELA
FKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFP
GSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMT
LAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEE

--------------------------------------------------------------
>In-frame_ENST00000265284_ENST00000225983_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(transcript)=4154nt_BP=754nt
ATGAGCCGCGCGCCTCTGCCGAGCGCAGCCAACTAAATCGGCTTGGATGATTCGCGACCTGAGCAAGATGTACCCGCAGACCAGACACCC
AGCACCGCATCAGCCTGCTCAACCCTTTAAATTTACAATTTCCGAATCCTGTGATCGGATTAAGGAAGAGTTTCAGTTTTTACAGGCTCA
ATACCACAGTCTGAAGCTGGAATGTGAGAAACTCGCCAGTGAGAAGACAGAGATGCAGCGGCATTATGTCATGTATTATGAAATGTCCTA
TGGGTTGAATATAGAAATGCACAAGCAGGCAGAGATTGTCAAGAGGCTGAATGCTATCTGTGCACAAGTCATTCCTTTCCTGTCCCAAGA
GCAACAACTCCAGGCCCAGCATTTATCACATGGACATGGTCTCCCCGTACCTCTGACTCCACACCCTTCAGGGCTCCAGCCCCCTGCCAT
TCCACCCATCGGTAGCAGTGCCGGGCTTCTGGCCCTCTCCAGTGCTCTAGGAGGTCAGTCCCATCTTCCAATTAAAGATGAGAAGAAGCA
CCATGACAATGATCACCAAAGAGACAGAGACTCCATCAAGAGCTCTTCAGTATCCCCATCAGCCAGTTTCCGAGGTGCTGAGAAGCACAG
AAACTCCGCAGACTACTCCTCAGAGAGCAAAAAGCAGAAAACTGAAGAAAAGGAAATTGCAGCTCGTTATGACAGCGATGGTGAGAAAAG
TGATGACAACTTGGTGGTTGACGTTTCCAATGAGATCCTCACCAAGACAGGGGAGCTGCCCAGGCAGCCCACCACCCACCCTGAGGAGAC
AGAGGAGGAGCTGACGGAGCAGCAGGAGGTCTTGCTGGGGGAGGGAGCCCTGACCATGCCCCGGGAGGGCTCCACAGAGAGTGAGAGCAC
ACAGGAAGACCTGGAGGAGGAGGACGAGGAAGACGATGGGGAGGAGGAGGAGGATTGCATCCAGGTTAAGGACGAGGAGGGCGAGAGTGG
TGCTGAGGAGGGGCCCGACTTGGAGGAGCCTGGTGCTGGATACAAAAAACTGTTCTCAGATGCCCAGCCGCTGCAGCCTTTGCAGGTGTA
CCAGGCGCCCCTCAGCCTGGCCACTGTGCCCCACCAGGCCCTGGGCCGTACCCAGTCCTCCCCTGCTGCCCCTGGGGGCATGAAGAGCCC
CCCAGACCAGCCCGTCAAGCACCTCTTCACCACAGGTGTGGTCTACGACACGTTCATGCTAAAGCACCAGTGCATGTGCGGGAACACACA
CGTGCACCCTGAGCATGCTGGCCGGATCCAGAGCATCTGGTCCCGGCTGCAGGAGACAGGCCTGCTTAGCAAGTGCGAGCGGATCCGAGG
TCGCAAAGCCACGCTAGATGAGATCCAGACAGTGCACTCTGAATACCACACCCTGCTCTATGGGACCAGTCCCCTCAACCGGCAGAAGCT
AGACAGCAAGAAGTTGCTCGGCCCCATCAGCCAGAAGATGTATGCTGTGCTGCCTTGTGGGGGCATCGGGGTGGACAGTGACACCGTGTG
GAATGAGATGCACTCCTCCAGTGCTGTGCGCATGGCAGTGGGCTGCCTGCTGGAGCTGGCCTTCAAGGTGGCTGCAGGAGAGCTCAAGAA
TGGATTTGCCATCATCCGGCCCCCAGGACACCACGCCGAGGAATCCACAGCCATGGGATTCTGCTTCTTCAACTCTGTAGCCATCACCGC
AAAACTCCTACAGCAGAAGTTGAACGTGGGCAAGGTCCTCATCGTGGACTGGGACATTCACCATGGCAATGGCACCCAGCAGGCGTTCTA
CAATGACCCCTCTGTGCTCTACATCTCTCTGCATCGCTATGACAACGGGAACTTCTTTCCAGGCTCTGGGGCTCCTGAAGAGGTTGGTGG
AGGACCAGGCGTGGGGTACAATGTGAACGTGGCATGGACAGGAGGTGTGGACCCCCCCATTGGAGACGTGGAGTACCTTACAGCCTTCAG
GACAGTGGTGATGCCCATTGCCCACGAGTTCTCACCTGATGTGGTCCTAGTCTCCGCCGGGTTTGATGCTGTTGAAGGACATCTGTCTCC
TCTGGGTGGCTACTCTGTCACCGCCAGATGTTTTGGCCACTTGACCAGGCAGCTGATGACCCTGGCAGGGGGCCGGGTGGTGCTGGCCCT
GGAGGGAGGCCATGACTTGACCGCCATCTGTGATGCCTCTGAGGCTTGTGTCTCGGCTCTGCTCAGTGTAGAGCTGCAGCCCTTGGATGA
GGCAGTCTTGCAGCAAAAGCCCAACATCAACGCAGTGGCCACGCTAGAGAAAGTCATCGAGATCCAGAGCAAACACTGGAGCTGTGTGCA
GAAGTTCGCCGCTGGTCTGGGCCGGTCCCTGCGAGAGGCCCAAGCAGGTGAGACCGAGGAGGCCGAGACTGTGAGCGCCATGGCCTTGCT
GTCGGTGGGGGCCGAGCAGGCCCAGGCTGCGGCAGCCCGGGAACACAGCCCCAGGCCGGCAGAGGAGCCCATGGAGCAGGAGCCTGCCCT
GTGACGCCCCGGCCCCCATCCCTCTGGGCTTCACCATTGTGATTTTGTTTATTTTTTCTATTAAAAACAAAAAGTCACACATTCAACAAG
GTGTGCCGTGTGGGTCTCTCAGCCTTGCCCCTCCTGCTCCTCTACGCTGCCTCAGGCCCCCAGCCCTGTGGCTTCCACCTCAGCTCTAGA
AGCCTGCTCCCTCTGCAGGGGGTGGTGGTGTCTTCCCAGCCCTGTCCCATGTGTCCCTCCCCCCATTTTCCTGCATTCTGTCTGTCCTTT
TCCTCCTTGGAGCCTGGGCCAGCTCAAGGTGGGCACGGGGGCCCAGACAGTACTCTCCAGTTCTGGGGCCCCCCGAGTGAGGAGGGAACG
GGAAGTCGGTGCCTTGGTTTCAGCTGATTTGGGGGGAAATGCCTTAATTTCACTCTCCTCCCTTCTCCAGCCTCAGGGGAGGATCTGGAG
GATCCACTACTGTCTTTAAGATGCAGAGTGGAGGGGAGGTGGGCACCCACCCTGCGATTCTCCACCCTTTCCCCTTCTTTCGTCCTCACC
ATCTCTGCAGACCCCTCTCCTCCTCCTTCCTCTTGGTCTCAGCACTGATGGGAGGCTGGTGCCCAAGCTGTGGCCTGCAGTCTGTGAGGA
GGGCTGTCTTGCCTCACACTCCTCACAGCCTACTTCCCCTTCCCCGGGGCTGAGAGGGTGAAAGTGTGTGGGGAAGGAGAGGACTGGTTT
CCTGGGTTCTCAGGGGCCAGGAGGAGTAACAGAACCAGGTCTGCTCCCCACCTTACTCGGATGGCCTCCCTGCCCCTCTGCTGGCACAGC
CTGGGCAAGGGGAGAAGGTGGTCCCTGCAGAGGGGCTCCAGGCTGGTGAGAGCCCCCCTGCTGTCAGGACCAGATTTTCCCAGCCATCCA
GCATGCTGCGGGGAGAAGGGGCAGAGGCTCACCTCCCTCCTGGGGCCTTTTGTTTTGGATCCTGGGGATGGTGAGAATGGAGGTTCTAGA
AGGGGTAAGGCCAGAACCCAGGGATCCAGGAGTCGGCTCTCAGCTGGAGCTTCCATACCTTCTGGGCTCCCTTTGCTGACCACCAGCCCA
AGGGAGCTAAGACCAGGAGGGGGCTGGGCGCTGTCCCTTCTCTTTCCCAGGAGCCCTGCCAGGGGCTGTGGGCCTACAAGGCTTCCAGGG
GATGCCATCCAGCCTGTAGGAAACCAAAGATGGGAAGTGGCTCCTAGGGGGCTGACTCTTCCTTCCTCCTCCTCCCCAGTACCACATATA
CTTTCTCTCCTTCTATCTCCAGGGCCCCACCAATCTGTTTACATATTTATTATCCTATGGGGGCCTGAGCAGGATTGAGGGAGCCAGGGG
AGGGGCAGGAGTCCCAGCACCATCGGTTCATAGTGTGCTTGTGTGTTTGTTTTAGATCCTCCTGGGGGATGGGGATGGGGCCAGGCTCAG
TGTACTAGGCCTCTCTGTGCTGAGCCCCAGGCTCCCGGCCCCTTACCCACTCTCTCCCTGTGGCTGGTCTGGTTCTCATGTAAACCCACT
CCTTGCTTTGTCTCCCTGGATATGGATTTCAGTTAAGTATTTTGTAACCCGTTACACTGTGTGTCCTTGTGTAAATAAACTTGTTTCTGG

>In-frame_ENST00000265284_ENST00000225983_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(amino acids)=825AA_start in transcript=46_stop in transcript=2523
MIRDLSKMYPQTRHPAPHQPAQPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQAEIVKR
LNAICAQVIPFLSQEQQLQAQHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQSHLPIKDEKKHHDNDHQRDRDSIKSS
SVSPSASFRGAEKHRNSADYSSESKKQKTEEKEIAARYDSDGEKSDDNLVVDVSNEILTKTGELPRQPTTHPEETEEELTEQQEVLLGEG
ALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALG
RTQSSPAAPGGMKSPPDQPVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQTVHSEY
HTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEES
TAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNVAWTGG
VDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEA
CVSALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQAAAAREH

--------------------------------------------------------------
>In-frame_ENST00000265284_ENST00000393622_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(transcript)=4147nt_BP=754nt
ATGAGCCGCGCGCCTCTGCCGAGCGCAGCCAACTAAATCGGCTTGGATGATTCGCGACCTGAGCAAGATGTACCCGCAGACCAGACACCC
AGCACCGCATCAGCCTGCTCAACCCTTTAAATTTACAATTTCCGAATCCTGTGATCGGATTAAGGAAGAGTTTCAGTTTTTACAGGCTCA
ATACCACAGTCTGAAGCTGGAATGTGAGAAACTCGCCAGTGAGAAGACAGAGATGCAGCGGCATTATGTCATGTATTATGAAATGTCCTA
TGGGTTGAATATAGAAATGCACAAGCAGGCAGAGATTGTCAAGAGGCTGAATGCTATCTGTGCACAAGTCATTCCTTTCCTGTCCCAAGA
GCAACAACTCCAGGCCCAGCATTTATCACATGGACATGGTCTCCCCGTACCTCTGACTCCACACCCTTCAGGGCTCCAGCCCCCTGCCAT
TCCACCCATCGGTAGCAGTGCCGGGCTTCTGGCCCTCTCCAGTGCTCTAGGAGGTCAGTCCCATCTTCCAATTAAAGATGAGAAGAAGCA
CCATGACAATGATCACCAAAGAGACAGAGACTCCATCAAGAGCTCTTCAGTATCCCCATCAGCCAGTTTCCGAGGTGCTGAGAAGCACAG
AAACTCCGCAGACTACTCCTCAGAGAGCAAAAAGCAGAAAACTGAAGAAAAGGAAATTGCAGCTCGTTATGACAGCGATGGTGAGAAAAG
TGATGACAACTTGGTGGTTGACGTTTCCAATGAGATCCTCACCAAGACAGGGGAGCTGCCCAGGCAGCCCACCACCCACCCTGAGGAGAC
AGAGGAGGAGCTGACGGAGCAGCAGGAGGTCTTGCTGGGGGAGGGAGCCCTGACCATGCCCCGGGAGGGCTCCACAGAGAGTGAGAGCAC
ACAGGAAGACCTGGAGGAGGAGGACGAGGAAGACGATGGGGAGGAGGAGGAGGATTGCATCCAGGTTAAGGACGAGGAGGGCGAGAGTGG
TGCTGAGGAGGGGCCCGACTTGGAGGAGCCTGGTGCTGGATACAAAAAACTGTTCTCAGATGCCCAGCCGCTGCAGCCTTTGCAGGTGTA
CCAGGCGCCCCTCAGCCTGGCCACTGTGCCCCACCAGGCCCTGGGCCGTACCCAGTCCTCCCCTGCTGCCCCTGGGGGCATGAAGAGCCC
CCCAGACCAGCCCGTCAAGCACCTCTTCACCACAGGTGTGGTCTACGACACGTTCATGCTAAAGCACCAGTGCATGTGCGGGAACACACA
CGTGCACCCTGAGCATGCTGGCCGGATCCAGAGCATCTGGTCCCGGCTGCAGGAGACAGGCCTGCTTAGCAAGTGCGAGCGGATCCGAGG
TCGCAAAGCCACGCTAGATGAGATCCAGACAGTGCACTCTGAATACCACACCCTGCTCTATGGGACCAGTCCCCTCAACCGGCAGAAGCT
AGACAGCAAGAAGTTGCTCGGCCCCATCAGCCAGAAGATGTATGCTGTGCTGCCTTGTGGGGGCATCGGGGTGGACAGTGACACCGTGTG
GAATGAGATGCACTCCTCCAGTGCTGTGCGCATGGCAGTGGGCTGCCTGCTGGAGCTGGCCTTCAAGGTGGCTGCAGGAGAGCTCAAGAA
TGGATTTGCCATCATCCGGCCCCCAGGACACCACGCCGAGGAATCCACAGCCATGGGATTCTGCTTCTTCAACTCTGTAGCCATCACCGC
AAAACTCCTACAGCAGAAGTTGAACGTGGGCAAGGTCCTCATCGTGGACTGGGACATTCACCATGGCAATGGCACCCAGCAGGCGTTCTA
CAATGACCCCTCTGTGCTCTACATCTCTCTGCATCGCTATGACAACGGGAACTTCTTTCCAGGCTCTGGGGCTCCTGAAGAGGTTGGTGG
AGGACCAGGCGTGGGGTACAATGTGAACGTGGCATGGACAGGAGGTGTGGACCCCCCCATTGGAGACGTGGAGTACCTTACAGCCTTCAG
GACAGTGGTGATGCCCATTGCCCACGAGTTCTCACCTGATGTGGTCCTAGTCTCCGCCGGGTTTGATGCTGTTGAAGGACATCTGTCTCC
TCTGGGTGGCTACTCTGTCACCGCCAGATGTTTTGGCCACTTGACCAGGCAGCTGATGACCCTGGCAGGGGGCCGGGTGGTGCTGGCCCT
GGAGGGAGGCCATGACTTGACCGCCATCTGTGATGCCTCTGAGGCTTGTGTCTCGGCTCTGCTCAGTGTAGAGCTGCAGCCCTTGGATGA
GGCAGTCTTGCAGCAAAAGCCCAACATCAACGCAGTGGCCACGCTAGAGAAAGTCATCGAGATCCAGAGCAAACACTGGAGCTGTGTGCA
GAAGTTCGCCGCTGGTCTGGGCCGGTCCCTGCGAGAGGCCCAAGCAGGTGAGACCGAGGAGGCCGAGACTGTGAGCGCCATGGCCTTGCT
GTCGGTGGGGGCCGAGCAGGCCCAGGCTGCGGCAGCCCGGGAACACAGCCCCAGGCCGGCAGAGGAGCCCATGGAGCAGGAGCCTGCCCT
GTGACGCCCCGGCCCCCATCCCTCTGGGCTTCACCATTGTGATTTTGTTTATTTTTTCTATTAAAAACAAAAAGTCACACATTCAACAAG
GTGTGCCGTGTGGGTCTCTCAGCCTTGCCCCTCCTGCTCCTCTACGCTGCCTCAGGCCCCCAGCCCTGTGGCTTCCACCTCAGCTCTAGA
AGCCTGCTCCCTCTGCAGGGGGTGGTGGTGTCTTCCCAGCCCTGTCCCATGTGTCCCTCCCCCCATTTTCCTGCATTCTGTCTGTCCTTT
TCCTCCTTGGAGCCTGGGCCAGCTCAAGGTGGGCACGGGGGCCCAGACAGTACTCTCCAGTTCTGGGGCCCCCCGAGTGAGGAGGGAACG
GGAAGTCGGTGCCTTGGTTTCAGCTGATTTGGGGGGAAATGCCTTAATTTCACTCTCCTCCCTTCTCCAGCCTCAGGGGAGGATCTGGAG
GATCCACTACTGTCTTTAAGATGCAGAGTGGAGGGGAGGTGGGCACCCACCCTGCGATTCTCCACCCTTTCCCCTTCTTTCGTCCTCACC
ATCTCTGCAGACCCCTCTCCTCCTCCTTCCTCTTGGTCTCAGCACTGATGGGAGGCTGGTGCCCAAGCTGTGGCCTGCAGTCTGTGAGGA
GGGCTGTCTTGCCTCACACTCCTCACAGCCTACTTCCCCTTCCCCGGGGCTGAGAGGGTGAAAGTGTGTGGGGAAGGAGAGGACTGGTTT
CCTGGGTTCTCAGGGGCCAGGAGGAGTAACAGAACCAGGTCTGCTCCCCACCTTACTCGGATGGCCTCCCTGCCCCTCTGCTGGCACAGC
CTGGGCAAGGGGAGAAGGTGGTCCCTGCAGAGGGGCTCCAGGCTGGTGAGAGCCCCCCTGCTGTCAGGACCAGATTTTCCCAGCCATCCA
GCATGCTGCGGGGAGAAGGGGCAGAGGCTCACCTCCCTCCTGGGGCCTTTTGTTTTGGATCCTGGGGATGGTGAGAATGGAGGTTCTAGA
AGGGGTAAGGCCAGAACCCAGGGATCCAGGAGTCGGCTCTCAGCTGGAGCTTCCATACCTTCTGGGCTCCCTTTGCTGACCACCAGCCCA
AGGGAGCTAAGACCAGGAGGGGGCTGGGCGCTGTCCCTTCTCTTTCCCAGGAGCCCTGCCAGGGGCTGTGGGCCTACAAGGCTTCCAGGG
GATGCCATCCAGCCTGTAGGAAACCAAAGATGGGAAGTGGCTCCTAGGGGGCTGACTCTTCCTTCCTCCTCCTCCCCAGTACCACATATA
CTTTCTCTCCTTCTATCTCCAGGGCCCCACCAATCTGTTTACATATTTATTATCCTATGGGGGCCTGAGCAGGATTGAGGGAGCCAGGGG
AGGGGCAGGAGTCCCAGCACCATCGGTTCATAGTGTGCTTGTGTGTTTGTTTTAGATCCTCCTGGGGGATGGGGATGGGGCCAGGCTCAG
TGTACTAGGCCTCTCTGTGCTGAGCCCCAGGCTCCCGGCCCCTTACCCACTCTCTCCCTGTGGCTGGTCTGGTTCTCATGTAAACCCACT
CCTTGCTTTGTCTCCCTGGATATGGATTTCAGTTAAGTATTTTGTAACCCGTTACACTGTGTGTCCTTGTGTAAATAAACTTGTTTCTGG

>In-frame_ENST00000265284_ENST00000393622_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(amino acids)=825AA_start in transcript=46_stop in transcript=2523
MIRDLSKMYPQTRHPAPHQPAQPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQAEIVKR
LNAICAQVIPFLSQEQQLQAQHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQSHLPIKDEKKHHDNDHQRDRDSIKSS
SVSPSASFRGAEKHRNSADYSSESKKQKTEEKEIAARYDSDGEKSDDNLVVDVSNEILTKTGELPRQPTTHPEETEEELTEQQEVLLGEG
ALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALG
RTQSSPAAPGGMKSPPDQPVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQTVHSEY
HTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEES
TAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNVAWTGG
VDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEA
CVSALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQAAAAREH

--------------------------------------------------------------
>In-frame_ENST00000265284_ENST00000336057_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(transcript)=3891nt_BP=754nt
ATGAGCCGCGCGCCTCTGCCGAGCGCAGCCAACTAAATCGGCTTGGATGATTCGCGACCTGAGCAAGATGTACCCGCAGACCAGACACCC
AGCACCGCATCAGCCTGCTCAACCCTTTAAATTTACAATTTCCGAATCCTGTGATCGGATTAAGGAAGAGTTTCAGTTTTTACAGGCTCA
ATACCACAGTCTGAAGCTGGAATGTGAGAAACTCGCCAGTGAGAAGACAGAGATGCAGCGGCATTATGTCATGTATTATGAAATGTCCTA
TGGGTTGAATATAGAAATGCACAAGCAGGCAGAGATTGTCAAGAGGCTGAATGCTATCTGTGCACAAGTCATTCCTTTCCTGTCCCAAGA
GCAACAACTCCAGGCCCAGCATTTATCACATGGACATGGTCTCCCCGTACCTCTGACTCCACACCCTTCAGGGCTCCAGCCCCCTGCCAT
TCCACCCATCGGTAGCAGTGCCGGGCTTCTGGCCCTCTCCAGTGCTCTAGGAGGTCAGTCCCATCTTCCAATTAAAGATGAGAAGAAGCA
CCATGACAATGATCACCAAAGAGACAGAGACTCCATCAAGAGCTCTTCAGTATCCCCATCAGCCAGTTTCCGAGGTGCTGAGAAGCACAG
AAACTCCGCAGACTACTCCTCAGAGAGCAAAAAGCAGAAAACTGAAGAAAAGGAAATTGCAGCTCGTTATGACAGCGATGGTGAGAAAAG
TGATGACAACTTGGTGGTTGACGTTTCCAATGAGATCCTCACCAAGACAGGGGAGCTGCCCAGGCAGCCCACCACCCACCCTGAGGAGAC
AGAGGAGGAGCTGACGGAGCAGCAGGAGGTCTTGCTGGGGGAGGGAGCCCTGACCATGCCCCGGGAGGGCTCCACAGAGAGTGAGAGCAC
ACAGGAAGACCTGGAGGAGGAGGACGAGGAAGACGATGGGGAGGAGGAGGAGGATTGCATCCAGGTTAAGGACGAGGAGGGCGAGAGTGG
TGCTGAGGAGGGGCCCGACTTGGAGGAGCCTGGTGCTGGATACAAAAAACTGTTCTCAGATGCCCAGCCGCTGCAGCCTTTGCAGGTGTA
CCAGGCGCCCCTCAGCCTGGCCACTGTGCCCCACCAGGCCCTGGGCCGTACCCAGTCCTCCCCTGCTGCCCCTGGGGGCATGAAGAGCCC
CCCAGACCAGCCCGTCAAGCACCTCTTCACCACAGGCCCCATCAGCCAGAAGATGTATGCTGTGCTGCCTTGTGGGGGCATCGGGGTGGA
CAGTGACACCGTGTGGAATGAGATGCACTCCTCCAGTGCTGTGCGCATGGCAGTGGGCTGCCTGCTGGAGCTGGCCTTCAAGGTGGCTGC
AGGAGAGCTCAAGAATGGATTTGCCATCATCCGGCCCCCAGGACACCACGCCGAGGAATCCACAGCCATGGGATTCTGCTTCTTCAACTC
TGTAGCCATCACCGCAAAACTCCTACAGCAGAAGTTGAACGTGGGCAAGGTCCTCATCGTGGACTGGGACATTCACCATGGCAATGGCAC
CCAGCAGGCGTTCTACAATGACCCCTCTGTGCTCTACATCTCTCTGCATCGCTATGACAACGGGAACTTCTTTCCAGGCTCTGGGGCTCC
TGAAGAGGTTGGTGGAGGACCAGGCGTGGGGTACAATGTGAACGTGGCATGGACAGGAGGTGTGGACCCCCCCATTGGAGACGTGGAGTA
CCTTACAGCCTTCAGGACAGTGGTGATGCCCATTGCCCACGAGTTCTCACCTGATGTGGTCCTAGTCTCCGCCGGGTTTGATGCTGTTGA
AGGACATCTGTCTCCTCTGGGTGGCTACTCTGTCACCGCCAGATGTTTTGGCCACTTGACCAGGCAGCTGATGACCCTGGCAGGGGGCCG
GGTGGTGCTGGCCCTGGAGGGAGGCCATGACTTGACCGCCATCTGTGATGCCTCTGAGGCTTGTGTCTCGGCTCTGCTCAGTGTAGAGCT
GCAGCCCTTGGATGAGGCAGTCTTGCAGCAAAAGCCCAACATCAACGCAGTGGCCACGCTAGAGAAAGTCATCGAGATCCAGAGCAAACA
CTGGAGCTGTGTGCAGAAGTTCGCCGCTGGTCTGGGCCGGTCCCTGCGAGAGGCCCAAGCAGGTGAGACCGAGGAGGCCGAGACTGTGAG
CGCCATGGCCTTGCTGTCGGTGGGGGCCGAGCAGGCCCAGGCTGCGGCAGCCCGGGAACACAGCCCCAGGCCGGCAGAGGAGCCCATGGA
GCAGGAGCCTGCCCTGTGACGCCCCGGCCCCCATCCCTCTGGGCTTCACCATTGTGATTTTGTTTATTTTTTCTATTAAAAACAAAAAGT
CACACATTCAACAAGGTGTGCCGTGTGGGTCTCTCAGCCTTGCCCCTCCTGCTCCTCTACGCTGCCTCAGGCCCCCAGCCCTGTGGCTTC
CACCTCAGCTCTAGAAGCCTGCTCCCTCTGCAGGGGGTGGTGGTGTCTTCCCAGCCCTGTCCCATGTGTCCCTCCCCCCATTTTCCTGCA
TTCTGTCTGTCCTTTTCCTCCTTGGAGCCTGGGCCAGCTCAAGGTGGGCACGGGGGCCCAGACAGTACTCTCCAGTTCTGGGGCCCCCCG
AGTGAGGAGGGAACGGGAAGTCGGTGCCTTGGTTTCAGCTGATTTGGGGGGAAATGCCTTAATTTCACTCTCCTCCCTTCTCCAGCCTCA
GGGGAGGATCTGGAGGATCCACTACTGTCTTTAAGATGCAGAGTGGAGGGGAGGTGGGCACCCACCCTGCGATTCTCCACCCTTTCCCCT
TCTTTCGTCCTCACCATCTCTGCAGACCCCTCTCCTCCTCCTTCCTCTTGGTCTCAGCACTGATGGGAGGCTGGTGCCCAAGCTGTGGCC
TGCAGTCTGTGAGGAGGGCTGTCTTGCCTCACACTCCTCACAGCCTACTTCCCCTTCCCCGGGGCTGAGAGGGTGAAAGTGTGTGGGGAA
GGAGAGGACTGGTTTCCTGGGTTCTCAGGGGCCAGGAGGAGTAACAGAACCAGGTCTGCTCCCCACCTTACTCGGATGGCCTCCCTGCCC
CTCTGCTGGCACAGCCTGGGCAAGGGGAGAAGGTGGTCCCTGCAGAGGGGCTCCAGGCTGGTGAGAGCCCCCCTGCTGTCAGGACCAGAT
TTTCCCAGCCATCCAGCATGCTGCGGGGAGAAGGGGCAGAGGCTCACCTCCCTCCTGGGGCCTTTTGTTTTGGATCCTGGGGATGGTGAG
AATGGAGGTTCTAGAAGGGGTAAGGCCAGAACCCAGGGATCCAGGAGTCGGCTCTCAGCTGGAGCTTCCATACCTTCTGGGCTCCCTTTG
CTGACCACCAGCCCAAGGGAGCTAAGACCAGGAGGGGGCTGGGCGCTGTCCCTTCTCTTTCCCAGGAGCCCTGCCAGGGGCTGTGGGCCT
ACAAGGCTTCCAGGGGATGCCATCCAGCCTGTAGGAAACCAAAGATGGGAAGTGGCTCCTAGGGGGCTGACTCTTCCTTCCTCCTCCTCC
CCAGTACCACATATACTTTCTCTCCTTCTATCTCCAGGGCCCCACCAATCTGTTTACATATTTATTATCCTATGGGGGCCTGAGCAGGAT
TGAGGGAGCCAGGGGAGGGGCAGGAGTCCCAGCACCATCGGTTCATAGTGTGCTTGTGTGTTTGTTTTAGATCCTCCTGGGGGATGGGGA
TGGGGCCAGGCTCAGTGTACTAGGCCTCTCTGTGCTGAGCCCCAGGCTCCCGGCCCCTTACCCACTCTCTCCCTGTGGCTGGTCTGGTTC
TCATGTAAACCCACTCCTTGCTTTGTCTCCCTGGATATGGATTTCAGTTAAGTATTTTGTAACCCGTTACACTGTGTGTCCTTGTGTAAA

>In-frame_ENST00000265284_ENST00000336057_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(amino acids)=740AA_start in transcript=46_stop in transcript=2268
MIRDLSKMYPQTRHPAPHQPAQPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQAEIVKR
LNAICAQVIPFLSQEQQLQAQHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQSHLPIKDEKKHHDNDHQRDRDSIKSS
SVSPSASFRGAEKHRNSADYSSESKKQKTEEKEIAARYDSDGEKSDDNLVVDVSNEILTKTGELPRQPTTHPEETEEELTEQQEVLLGEG
ALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALG
RTQSSPAAPGGMKSPPDQPVKHLFTTGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGH
HAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNV
AWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAIC
DASEACVSALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQAA

--------------------------------------------------------------
>In-frame_ENST00000265284_ENST00000586802_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(transcript)=2606nt_BP=754nt
ATGAGCCGCGCGCCTCTGCCGAGCGCAGCCAACTAAATCGGCTTGGATGATTCGCGACCTGAGCAAGATGTACCCGCAGACCAGACACCC
AGCACCGCATCAGCCTGCTCAACCCTTTAAATTTACAATTTCCGAATCCTGTGATCGGATTAAGGAAGAGTTTCAGTTTTTACAGGCTCA
ATACCACAGTCTGAAGCTGGAATGTGAGAAACTCGCCAGTGAGAAGACAGAGATGCAGCGGCATTATGTCATGTATTATGAAATGTCCTA
TGGGTTGAATATAGAAATGCACAAGCAGGCAGAGATTGTCAAGAGGCTGAATGCTATCTGTGCACAAGTCATTCCTTTCCTGTCCCAAGA
GCAACAACTCCAGGCCCAGCATTTATCACATGGACATGGTCTCCCCGTACCTCTGACTCCACACCCTTCAGGGCTCCAGCCCCCTGCCAT
TCCACCCATCGGTAGCAGTGCCGGGCTTCTGGCCCTCTCCAGTGCTCTAGGAGGTCAGTCCCATCTTCCAATTAAAGATGAGAAGAAGCA
CCATGACAATGATCACCAAAGAGACAGAGACTCCATCAAGAGCTCTTCAGTATCCCCATCAGCCAGTTTCCGAGGTGCTGAGAAGCACAG
AAACTCCGCAGACTACTCCTCAGAGAGCAAAAAGCAGAAAACTGAAGAAAAGGAAATTGCAGCTCGTTATGACAGCGATGGTGAGAAAAG
TGATGACAACTTGGTGGTTGACGTTTCCAATGAGATCCTCACCAAGACAGGGGAGCTGCCCAGGCAGCCCACCACCCACCCTGAGGAGAC
AGAGGAGGAGCTGACGGAGCAGCAGGAGGTCTTGCTGGGGGAGGGAGCCCTGACCATGCCCCGGGAGGGCTCCACAGAGAGTGAGAGCAC
ACAGGAAGACCTGGAGGAGGAGGACGAGGAAGACGATGGGGAGGAGGAGGAGGATTGCATCCAGGTTAAGGACGAGGAGGGCGAGAGTGG
TGCTGAGGAGGGGCCCGACTTGGAGGAGCCTGGTGCTGGATACAAAAAACTGTTCTCAGATGCCCAGCCGCTGCAGCCTTTGCAGGTGTA
CCAGGCGCCCCTCAGCCTGGCCACTGTGCCCCACCAGGCCCTGGGCCGTACCCAGTCCTCCCCTGCTGCCCCTGGGGGCATGAAGAGCCC
CCCAGACCAGCCCGTCAAGCACCTCTTCACCACAGGTGTGGTCTACGACACGTTCATGCTAAAGCACCAGTGCATGTGCGGGAACACACA
CGTGCACCCTGAGCATGCTGGCCGGATCCAGAGCATCTGGTCCCGGCTGCAGGAGACAGGCCTGCTTAGCAAGTGCGAGCGGATCCGAGG
TCGCAAAGCCACGCTAGATGAGATCCAGACAGTGCACTCTGAATACCACACCCTGCTCTATGGGACCAGTCCCCTCAACCGGCAGAAGCT
AGACAGCAAGAAGTTGCTCGGCCCCATCAGCCAGAAGATGTATGCTGTGCTGCCTTGTGGGGGCATCGGGGTGGACAGTGACACCGTGTG
GAATGAGATGCACTCCTCCAGTGCTGTGCGCATGGCAGTGGGCTGCCTGCTGGAGCTGGCCTTCAAGGTGGCTGCAGGAGAGCTCAAGAA
TGGATTTGCCATCATCCGGCCCCCAGGACACCACGCCGAGGAATCCACAGCCATGGGATTCTGCTTCTTCAACTCTGTAGCCATCACCGC
AAAACTCCTACAGCAGAAGTTGAACGTGGGCAAGGTCCTCATCGTGGACTGGGACATTCACCATGGCAATGGCACCCAGCAGGCGTTCTA
CAATGACCCCTCTGTGCTCTACATCTCTCTGCATCGCTATGACAACGGGAACTTCTTTCCAGGCTCTGGGGCTCCTGAAGAGGTTGGTGG
AGGACCAGGCGTGGGGTACAATGTGAACGTGGCATGGACAGGAGGTGTGGACCCCCCCATTGGAGACGTGGAGTACCTTACAGCCTTCAG
GACAGTGGTGATGCCCATTGCCCACGAGTTCTCACCTGATGTGGTCCTAGTCTCCGCCGGGTTTGATGCTGTTGAAGGACATCTGTCTCC
TCTGGGTGGCTACTCTGTCACCGCCAGATGTTTTGGCCACTTGACCAGGCAGCTGATGACCCTGGCAGGGGGCCGGGTGGTGCTGGCCCT
GGAGGGAGGCCATGACTTGACCGCCATCTGTGATGCCTCTGAGGCTTGTGTCTCGGCTCTGCTCAGTGTAGAGCTGCAGCCCTTGGATGA
GGCAGTCTTGCAGCAAAAGCCCAACATCAACGCAGTGGCCACGCTAGAGAAAGTCATCGAGATCCAGAGCAAACACTGGAGCTGTGTGCA
GAAGTTCGCCGCTGGTCTGGGCCGGTCCCTGCGAGAGGCCCAAGCAGGTGAGACCGAGGAGGCCGAGACTGTGAGCGCCATGGCCTTGCT
GTCGGTGGGGGCCGAGCAGGCCCAGGCTGCGGCAGCCCGGGAACACAGCCCCAGGCCGGCAGAGGAGCCCATGGAGCAGGAGCCTGCCCT

>In-frame_ENST00000265284_ENST00000586802_TCGA-06-0749-01A_TLE4_chr9_82320857_+_HDAC5_chr17_42165064_length(amino acids)=825AA_start in transcript=46_stop in transcript=2523
MIRDLSKMYPQTRHPAPHQPAQPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQAEIVKR
LNAICAQVIPFLSQEQQLQAQHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQSHLPIKDEKKHHDNDHQRDRDSIKSS
SVSPSASFRGAEKHRNSADYSSESKKQKTEEKEIAARYDSDGEKSDDNLVVDVSNEILTKTGELPRQPTTHPEETEEELTEQQEVLLGEG
ALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALG
RTQSSPAAPGGMKSPPDQPVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQTVHSEY
HTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEES
TAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNVAWTGG
VDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEA
CVSALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQAAAAREH

--------------------------------------------------------------

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Fusion Gene PPI Analysis for TLE4-HDAC5


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TLE4-HDAC5


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TLE4-HDAC5


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneTLE4C0007097Carcinoma1CTD_human
HgeneTLE4C0024667Animal Mammary Neoplasms1CTD_human
HgeneTLE4C0024668Mammary Neoplasms, Experimental1CTD_human
HgeneTLE4C0151744Myocardial Ischemia1CTD_human
HgeneTLE4C0205696Anaplastic carcinoma1CTD_human
HgeneTLE4C0205697Carcinoma, Spindle-Cell1CTD_human
HgeneTLE4C0205698Undifferentiated carcinoma1CTD_human
HgeneTLE4C0205699Carcinomatosis1CTD_human
HgeneTLE4C1257925Mammary Carcinoma, Animal1CTD_human
TgeneHDAC5C0011570Mental Depression2PSYGENET
TgeneHDAC5C0011581Depressive disorder2PSYGENET
TgeneHDAC5C0001546Adjustment Disorders1CTD_human
TgeneHDAC5C0005586Bipolar Disorder1CTD_human
TgeneHDAC5C0005587Depression, Bipolar1CTD_human
TgeneHDAC5C0009171Cocaine Abuse1CTD_human
TgeneHDAC5C0011579Reactive depression1CTD_human
TgeneHDAC5C0024713Manic Disorder1CTD_human
TgeneHDAC5C0029456Osteoporosis1GENOMICS_ENGLAND
TgeneHDAC5C0036421Systemic Scleroderma1CTD_human
TgeneHDAC5C0041696Unipolar Depression1PSYGENET
TgeneHDAC5C0236736Cocaine-Related Disorders1CTD_human
TgeneHDAC5C0338831Manic1CTD_human
TgeneHDAC5C0340543Familial primary pulmonary hypertension1CTD_human
TgeneHDAC5C0600427Cocaine Dependence1CTD_human
TgeneHDAC5C1269683Major Depressive Disorder1PSYGENET
TgeneHDAC5C1522512Transient Situational Disturbance1CTD_human
TgeneHDAC5C1969342PULMONARY HYPERTENSION, PRIMARY, DEXFENFLURAMINE-ASSOCIATED1CTD_human
TgeneHDAC5C1969343Pulmonary Hypertension, Primary, Fenfluramine-Associated1CTD_human
TgeneHDAC5C3203102Idiopathic pulmonary arterial hypertension1CTD_human
TgeneHDAC5C3714844Pulmonary Hypertension, Primary, 1, With Hereditary Hemorrhagic Telangiectasia1CTD_human
TgeneHDAC5C4552070Pulmonary Hypertension, Primary, 11CTD_human