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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TLK2-IRAK3 (FusionGDB2 ID:90521)

Fusion Gene Summary for TLK2-IRAK3

check button Fusion gene summary
Fusion gene informationFusion gene name: TLK2-IRAK3
Fusion gene ID: 90521
HgeneTgene
Gene symbol

TLK2

IRAK3

Gene ID

11011

11213

Gene nametousled like kinase 2interleukin 1 receptor associated kinase 3
SynonymsHsHPK|MRD57|PKU-ALPHAASRT5|IRAKM
Cytomap

17q23.2

12q14.3

Type of geneprotein-codingprotein-coding
Descriptionserine/threonine-protein kinase tousled-like 2interleukin-1 receptor-associated kinase 3IL-1 receptor-associated kinase M
Modification date2020031320200313
UniProtAcc.

Q9Y616

Ensembl transtripts involved in fusion geneENST00000582809, ENST00000577616, 
ENST00000326270, ENST00000346027, 
ENST00000343388, ENST00000542523, 
ENST00000261233, ENST00000545837, 
ENST00000457197, 
Fusion gene scores* DoF score18 X 11 X 9=17824 X 4 X 4=64
# samples 245
** MAII scorelog2(24/1782*10)=-2.8923910259134
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/64*10)=-0.356143810225275
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TLK2 [Title/Abstract] AND IRAK3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTLK2(60679541)-IRAK3(66620503), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneTLK2

GO:0001672

regulation of chromatin assembly or disassembly

12660173

HgeneTLK2

GO:0006468

protein phosphorylation

12660173

HgeneTLK2

GO:0006974

cellular response to DNA damage stimulus

12660173

HgeneTLK2

GO:0018105

peptidyl-serine phosphorylation

20016786

HgeneTLK2

GO:0035556

intracellular signal transduction

12660173

HgeneTLK2

GO:0071480

cellular response to gamma radiation

12660173

TgeneIRAK3

GO:0006468

protein phosphorylation

10383454


check buttonFusion gene breakpoints across TLK2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across IRAK3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-FD-A6TG-01ATLK2chr17

60679541

+IRAK3chr12

66620503

+
ChimerDB4BLCATCGA-FD-A6TGTLK2chr17

60679541

+IRAK3chr12

66620502

+
ChimerDB4BLCATCGA-FD-A6TG-01ATLK2chr17

60679541

+IRAK3chr12

66620503

+


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Fusion Gene ORF analysis for TLK2-IRAK3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000582809ENST00000261233TLK2chr17

60679541

+IRAK3chr12

66620503

+
5CDS-intronENST00000582809ENST00000545837TLK2chr17

60679541

+IRAK3chr12

66620503

+
5CDS-intronENST00000582809ENST00000457197TLK2chr17

60679541

+IRAK3chr12

66620503

+
intron-3CDSENST00000577616ENST00000261233TLK2chr17

60679541

+IRAK3chr12

66620503

+
intron-intronENST00000577616ENST00000545837TLK2chr17

60679541

+IRAK3chr12

66620503

+
intron-intronENST00000577616ENST00000457197TLK2chr17

60679541

+IRAK3chr12

66620503

+
In-frameENST00000326270ENST00000261233TLK2chr17

60679541

+IRAK3chr12

66620503

+
5CDS-intronENST00000326270ENST00000545837TLK2chr17

60679541

+IRAK3chr12

66620503

+
5CDS-intronENST00000326270ENST00000457197TLK2chr17

60679541

+IRAK3chr12

66620503

+
In-frameENST00000346027ENST00000261233TLK2chr17

60679541

+IRAK3chr12

66620503

+
5CDS-intronENST00000346027ENST00000545837TLK2chr17

60679541

+IRAK3chr12

66620503

+
5CDS-intronENST00000346027ENST00000457197TLK2chr17

60679541

+IRAK3chr12

66620503

+
In-frameENST00000343388ENST00000261233TLK2chr17

60679541

+IRAK3chr12

66620503

+
5CDS-intronENST00000343388ENST00000545837TLK2chr17

60679541

+IRAK3chr12

66620503

+
5CDS-intronENST00000343388ENST00000457197TLK2chr17

60679541

+IRAK3chr12

66620503

+
In-frameENST00000542523ENST00000261233TLK2chr17

60679541

+IRAK3chr12

66620503

+
5CDS-intronENST00000542523ENST00000545837TLK2chr17

60679541

+IRAK3chr12

66620503

+
5CDS-intronENST00000542523ENST00000457197TLK2chr17

60679541

+IRAK3chr12

66620503

+
In-frameENST00000582809ENST00000261233TLK2chr17

60679541

+IRAK3chr12

66620502

+
5CDS-intronENST00000582809ENST00000545837TLK2chr17

60679541

+IRAK3chr12

66620502

+
5CDS-intronENST00000582809ENST00000457197TLK2chr17

60679541

+IRAK3chr12

66620502

+
intron-3CDSENST00000577616ENST00000261233TLK2chr17

60679541

+IRAK3chr12

66620502

+
intron-intronENST00000577616ENST00000545837TLK2chr17

60679541

+IRAK3chr12

66620502

+
intron-intronENST00000577616ENST00000457197TLK2chr17

60679541

+IRAK3chr12

66620502

+
In-frameENST00000326270ENST00000261233TLK2chr17

60679541

+IRAK3chr12

66620502

+
5CDS-intronENST00000326270ENST00000545837TLK2chr17

60679541

+IRAK3chr12

66620502

+
5CDS-intronENST00000326270ENST00000457197TLK2chr17

60679541

+IRAK3chr12

66620502

+
In-frameENST00000346027ENST00000261233TLK2chr17

60679541

+IRAK3chr12

66620502

+
5CDS-intronENST00000346027ENST00000545837TLK2chr17

60679541

+IRAK3chr12

66620502

+
5CDS-intronENST00000346027ENST00000457197TLK2chr17

60679541

+IRAK3chr12

66620502

+
In-frameENST00000343388ENST00000261233TLK2chr17

60679541

+IRAK3chr12

66620502

+
5CDS-intronENST00000343388ENST00000545837TLK2chr17

60679541

+IRAK3chr12

66620502

+
5CDS-intronENST00000343388ENST00000457197TLK2chr17

60679541

+IRAK3chr12

66620502

+
In-frameENST00000542523ENST00000261233TLK2chr17

60679541

+IRAK3chr12

66620502

+
5CDS-intronENST00000542523ENST00000545837TLK2chr17

60679541

+IRAK3chr12

66620502

+
5CDS-intronENST00000542523ENST00000457197TLK2chr17

60679541

+IRAK3chr12

66620502

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000582809TLK2chr1760679541+ENST00000261233IRAK3chr1266620503+970421153703252960
ENST00000326270TLK2chr1760679541+ENST00000261233IRAK3chr1266620503+9782219312133301069
ENST00000346027TLK2chr1760679541+ENST00000261233IRAK3chr1266620503+9719213012132671048
ENST00000343388TLK2chr1760679541+ENST00000261233IRAK3chr1266620503+94981909503046998
ENST00000542523TLK2chr1760679541+ENST00000261233IRAK3chr1266620503+93771788252925966
ENST00000582809TLK2chr1760679541+ENST00000261233IRAK3chr1266620502+970421153703252960
ENST00000326270TLK2chr1760679541+ENST00000261233IRAK3chr1266620502+9782219312133301069
ENST00000346027TLK2chr1760679541+ENST00000261233IRAK3chr1266620502+9719213012132671048
ENST00000343388TLK2chr1760679541+ENST00000261233IRAK3chr1266620502+94981909503046998
ENST00000542523TLK2chr1760679541+ENST00000261233IRAK3chr1266620502+93771788252925966

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000582809ENST00000261233TLK2chr1760679541+IRAK3chr1266620503+0.0003396190.9996604
ENST00000326270ENST00000261233TLK2chr1760679541+IRAK3chr1266620503+0.0001659410.99983406
ENST00000346027ENST00000261233TLK2chr1760679541+IRAK3chr1266620503+6.12E-050.9999387
ENST00000343388ENST00000261233TLK2chr1760679541+IRAK3chr1266620503+7.32E-050.9999268
ENST00000542523ENST00000261233TLK2chr1760679541+IRAK3chr1266620503+7.30E-050.99992704
ENST00000582809ENST00000261233TLK2chr1760679541+IRAK3chr1266620502+0.0003396190.9996604
ENST00000326270ENST00000261233TLK2chr1760679541+IRAK3chr1266620502+0.0001659410.99983406
ENST00000346027ENST00000261233TLK2chr1760679541+IRAK3chr1266620502+6.12E-050.9999387
ENST00000343388ENST00000261233TLK2chr1760679541+IRAK3chr1266620502+7.32E-050.9999268
ENST00000542523ENST00000261233TLK2chr1760679541+IRAK3chr1266620502+7.30E-050.99992704

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Fusion Genomic Features for TLK2-IRAK3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
TLK2chr1760679541+IRAK3chr1266620502+0.0013469930.99865294
TLK2chr1760679541+IRAK3chr1266620502+0.0013469930.99865294
TLK2chr1760679541+IRAK3chr1266620502+0.0013469930.99865294
TLK2chr1760679541+IRAK3chr1266620502+0.0013469930.99865294

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TLK2-IRAK3


check button Go to

FGviewer for the breakpoints of chr17:60679541-chr12:66620503

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.IRAK3

Q9Y616

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex. {ECO:0000250|UniProtKB:Q8K4B2, ECO:0000269|PubMed:10383454}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTLK2chr17:60679541chr12:66620502ENST00000326270+2023225_276641.6666666666666773.0Coiled coilOntology_term=ECO:0000255
HgeneTLK2chr17:60679541chr12:66620502ENST00000326270+2023317_347641.6666666666666773.0Coiled coilOntology_term=ECO:0000255
HgeneTLK2chr17:60679541chr12:66620502ENST00000326270+2023403_451641.6666666666666773.0Coiled coilOntology_term=ECO:0000255
HgeneTLK2chr17:60679541chr12:66620502ENST00000343388+1821225_276587.6666666666666719.0Coiled coilOntology_term=ECO:0000255
HgeneTLK2chr17:60679541chr12:66620502ENST00000343388+1821317_347587.6666666666666719.0Coiled coilOntology_term=ECO:0000255
HgeneTLK2chr17:60679541chr12:66620502ENST00000343388+1821403_451587.6666666666666719.0Coiled coilOntology_term=ECO:0000255
HgeneTLK2chr17:60679541chr12:66620502ENST00000346027+1922225_276619.6666666666666751.0Coiled coilOntology_term=ECO:0000255
HgeneTLK2chr17:60679541chr12:66620502ENST00000346027+1922317_347619.6666666666666751.0Coiled coilOntology_term=ECO:0000255
HgeneTLK2chr17:60679541chr12:66620502ENST00000346027+1922403_451619.6666666666666751.0Coiled coilOntology_term=ECO:0000255
HgeneTLK2chr17:60679541chr12:66620502ENST00000542523+1821225_276587.6666666666666719.0Coiled coilOntology_term=ECO:0000255
HgeneTLK2chr17:60679541chr12:66620502ENST00000542523+1821317_347587.6666666666666719.0Coiled coilOntology_term=ECO:0000255
HgeneTLK2chr17:60679541chr12:66620502ENST00000542523+1821403_451587.6666666666666719.0Coiled coilOntology_term=ECO:0000255
HgeneTLK2chr17:60679541chr12:66620503ENST00000326270+2023225_276641.6666666666666773.0Coiled coilOntology_term=ECO:0000255
HgeneTLK2chr17:60679541chr12:66620503ENST00000326270+2023317_347641.6666666666666773.0Coiled coilOntology_term=ECO:0000255
HgeneTLK2chr17:60679541chr12:66620503ENST00000326270+2023403_451641.6666666666666773.0Coiled coilOntology_term=ECO:0000255
HgeneTLK2chr17:60679541chr12:66620503ENST00000343388+1821225_276587.6666666666666719.0Coiled coilOntology_term=ECO:0000255
HgeneTLK2chr17:60679541chr12:66620503ENST00000343388+1821317_347587.6666666666666719.0Coiled coilOntology_term=ECO:0000255
HgeneTLK2chr17:60679541chr12:66620503ENST00000343388+1821403_451587.6666666666666719.0Coiled coilOntology_term=ECO:0000255
HgeneTLK2chr17:60679541chr12:66620503ENST00000346027+1922225_276619.6666666666666751.0Coiled coilOntology_term=ECO:0000255
HgeneTLK2chr17:60679541chr12:66620503ENST00000346027+1922317_347619.6666666666666751.0Coiled coilOntology_term=ECO:0000255
HgeneTLK2chr17:60679541chr12:66620503ENST00000346027+1922403_451619.6666666666666751.0Coiled coilOntology_term=ECO:0000255
HgeneTLK2chr17:60679541chr12:66620503ENST00000542523+1821225_276587.6666666666666719.0Coiled coilOntology_term=ECO:0000255
HgeneTLK2chr17:60679541chr12:66620503ENST00000542523+1821317_347587.6666666666666719.0Coiled coilOntology_term=ECO:0000255
HgeneTLK2chr17:60679541chr12:66620503ENST00000542523+1821403_451587.6666666666666719.0Coiled coilOntology_term=ECO:0000255
HgeneTLK2chr17:60679541chr12:66620502ENST00000326270+2023468_476641.6666666666666773.0Nucleotide bindingATP
HgeneTLK2chr17:60679541chr12:66620502ENST00000343388+1821468_476587.6666666666666719.0Nucleotide bindingATP
HgeneTLK2chr17:60679541chr12:66620502ENST00000346027+1922468_476619.6666666666666751.0Nucleotide bindingATP
HgeneTLK2chr17:60679541chr12:66620502ENST00000542523+1821468_476587.6666666666666719.0Nucleotide bindingATP
HgeneTLK2chr17:60679541chr12:66620503ENST00000326270+2023468_476641.6666666666666773.0Nucleotide bindingATP
HgeneTLK2chr17:60679541chr12:66620503ENST00000343388+1821468_476587.6666666666666719.0Nucleotide bindingATP
HgeneTLK2chr17:60679541chr12:66620503ENST00000346027+1922468_476619.6666666666666751.0Nucleotide bindingATP
HgeneTLK2chr17:60679541chr12:66620503ENST00000542523+1821468_476587.6666666666666719.0Nucleotide bindingATP
TgeneIRAK3chr17:60679541chr12:66620502ENST00000457197411165_452156.66666666666666536.0DomainProtein kinase
TgeneIRAK3chr17:60679541chr12:66620503ENST00000457197411165_452156.66666666666666536.0DomainProtein kinase
TgeneIRAK3chr17:60679541chr12:66620502ENST00000261233512295_298217.66666666666666597.0Nucleotide bindingATP
TgeneIRAK3chr17:60679541chr12:66620502ENST00000457197411171_179156.66666666666666536.0Nucleotide bindingATP
TgeneIRAK3chr17:60679541chr12:66620502ENST00000457197411295_298156.66666666666666536.0Nucleotide bindingATP
TgeneIRAK3chr17:60679541chr12:66620503ENST00000261233512295_298217.66666666666666597.0Nucleotide bindingATP
TgeneIRAK3chr17:60679541chr12:66620503ENST00000457197411171_179156.66666666666666536.0Nucleotide bindingATP
TgeneIRAK3chr17:60679541chr12:66620503ENST00000457197411295_298156.66666666666666536.0Nucleotide bindingATP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTLK2chr17:60679541chr12:66620502ENST00000326270+2023462_741641.6666666666666773.0DomainProtein kinase
HgeneTLK2chr17:60679541chr12:66620502ENST00000343388+1821462_741587.6666666666666719.0DomainProtein kinase
HgeneTLK2chr17:60679541chr12:66620502ENST00000346027+1922462_741619.6666666666666751.0DomainProtein kinase
HgeneTLK2chr17:60679541chr12:66620502ENST00000542523+1821462_741587.6666666666666719.0DomainProtein kinase
HgeneTLK2chr17:60679541chr12:66620503ENST00000326270+2023462_741641.6666666666666773.0DomainProtein kinase
HgeneTLK2chr17:60679541chr12:66620503ENST00000343388+1821462_741587.6666666666666719.0DomainProtein kinase
HgeneTLK2chr17:60679541chr12:66620503ENST00000346027+1922462_741619.6666666666666751.0DomainProtein kinase
HgeneTLK2chr17:60679541chr12:66620503ENST00000542523+1821462_741587.6666666666666719.0DomainProtein kinase
TgeneIRAK3chr17:60679541chr12:66620502ENST00000261233512165_452217.66666666666666597.0DomainProtein kinase
TgeneIRAK3chr17:60679541chr12:66620502ENST0000026123351241_106217.66666666666666597.0DomainDeath
TgeneIRAK3chr17:60679541chr12:66620502ENST0000045719741141_106156.66666666666666536.0DomainDeath
TgeneIRAK3chr17:60679541chr12:66620503ENST00000261233512165_452217.66666666666666597.0DomainProtein kinase
TgeneIRAK3chr17:60679541chr12:66620503ENST0000026123351241_106217.66666666666666597.0DomainDeath
TgeneIRAK3chr17:60679541chr12:66620503ENST0000045719741141_106156.66666666666666536.0DomainDeath
TgeneIRAK3chr17:60679541chr12:66620502ENST00000261233512171_179217.66666666666666597.0Nucleotide bindingATP
TgeneIRAK3chr17:60679541chr12:66620503ENST00000261233512171_179217.66666666666666597.0Nucleotide bindingATP


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Fusion Gene Sequence for TLK2-IRAK3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000582809_ENST00000261233_TCGA-FD-A6TG-01A_TLK2_chr17_60679541_+_IRAK3_chr12_66620503_length(transcript)=9704nt_BP=2115nt
GTTCAGAATACAGCTGAGCCCAGAGATTGCATGGCACCAAGAGAGGTTTCTGTCAAGCCGTCCCGTTCCGAGATGCCCCATCGCACCAAC
GAAGCAACTGCTGAGCAGAAATGATGGAAGAATTGCATAGCCTGGACCCACGACGGCAGGAATTATTGGAGGCCAGGTTTACTGGAGTAG
GTGTTAGTAAGGAAAACTAGAAAAGAGGAGGAAAAAACAATAAATATGCAAGAAGAAATAAATACATTGCAAAACAGAAGAATGGGAAAT
AATCAAGAGTTGGAAAATTAGGAAACAAAAGGCAAAATGAAGGAGAGTACATCGGATATAACAAAAGGGACCACTTAATAGTGAGTCTTC
CAACCAGAGCTTGTGCAGCGTCGGATCCTTGAGTGATAAAGAAGTAGAGACTCCCGAGAAAAAGCAGAATGACCAGCGAAATCGGAAAAG
AAAAGCTGAACCATATGAAACTAGCCAAGGGAAAGGCACTCCTAGGGGACATAAAATTAGTGATTACTTTGAGTTTGCTGGGGGAAGCGC
GCCAGGAACCAGCCCTGGCAGAAGTGTTCCACCAGTTGCACGATCCTCACCGCAACATTCCTTATCCAATCCCTTACCGCGACGAGTAGA
ACAGCCCCTCTATGGTTTAGATGGCAGTGCTGCAAAGGAGGCAACGGAGGAGCAGTCTGCTCTGCCAACCCTCATGTCAGTGATGCTAGC
AAAACCTCGGCTTGACACAGAGCAGCTGGCGCAAAGGGGAGCTGGCCTCTGCTTCACTTTTGTTTCAGCTCAGCAAAACAGTCCCTCATC
TACGGGATCTGGCAACACAGAGCATTCCTGCAGCTCCCAAAAACAGATCTCCATCCAGCACAGACAGACCCAGTCCGACCTCACAATAGA
AAAAATATCTGCACTAGAAAACAGTAAGAATTCTGACTTAGAGAAGAAGGAGGGAAGAATAGATGATTTATTAAGAGCCAACTGTGATTT
GAGACGGCAGATTGATGAACAGCAAAAGATGCTAGAGAAATACAAGGAACGATTAAATAGATGTGTGACAATGAGCAAGAAACTCCTTAT
AGAAAAGTCAAAACAAGAGAAGATGGCGTGTAGAGATAAGAGCATGCAAGACCGCTTGAGACTGGGCCACTTTACTACTGTCCGACACGG
AGCCTCATTTACTGAACAGTGGACAGATGGTTATGCTTTTCAGAATCTTATCAAGCAACAGGAAAGGATAAATTCACAGAGGGAAGAGAT
AGAAAGACAACGGAAAATGTTAGCAAAGCGGAAACCTCCTGCCATGGGTCAGGCCCCTCCTGCAACCAATGAGCAGAAACAGCGGAAAAG
CAAGACCAATGGAGCTGAAAATGAAACGTTAACGTTAGCAGAATACCATGAACAAGAAGAAATCTTCAAACTCAGATTAGGTCATCTTAA
AAAGGAGGAAGCAGAGATCCAGGCAGAGCTGGAGAGACTAGAAAGGGTTAGAAATCTACATATCAGGGAACTAAAAAGGATACATAATGA
AGATAATTCACAATTTAAAGATCATCCAACGCTAAATGACAGATATTTGTTGTTACATCTTTTGGGTAGAGGAGGTTTCAGTGAAGTTTA
CAAGGCATTTGATCTAACAGAGCAAAGATACGTAGCTGTGAAAATTCACCAGTTAAATAAAAACTGGAGAGATGAGAAAAAGGAGAATTA
CCACAAGCATGCATGTAGGGAATACCGGATTCATAAAGAGCTGGATCATCCCAGAATAGTTAAGCTGTATGATTACTTTTCACTGGATAC
TGACTCGTTTTGTACAGTATTAGAATACTGTGAGGGAAATGATCTGGACTTCTACCTGAAACAGCACAAATTAATGTCGGAGAAAGAGGC
CCGGTCCATTATCATGCAGATTGTGAATGCTTTAAAGTACTTAAATGAAATAAAACCTCCCATCATACACTATGACCTCAAACCAGGTAA
TATTCTTTTAGTAAATGGTACAGCGTGTGGAGAGATAAAAATTACAGATTTTGGTCTTTCGAAGATCATGGATGATGATAGCTACAATTC
AGTGGATGGCATGGAGCTAACATCACAAGGTGCTGGTACTTATTGGTTTCATCACCCAAACATACTAGAGTTGGCTGCATATTTTACAGA
GACTGAGAAGTTCTGTCTGATTTATCCATACATGAGAAATGGAACACTTTTTGACAGATTGCAGTGTGTAGGTGACACGGCCCCACTCCC
TTGGCACATTCGAATCGGTATATTAATAGGAATATCCAAAGCCATTCACTACCTGCACAACGTTCAACCATGCTCGGTCATCTGTGGCAG
TATATCAAGTGCAAACATCCTTTTGGATGATCAGTTTCAACCCAAACTAACTGATTTTGCCATGGCACACTTCCGGTCCCACCTAGAACA
TCAGAGTTGTACCATAAATATGACCAGCAGCAGCAGTAAACATCTGTGGTACATGCCAGAAGAGTACATCAGACAGGGGAAACTTTCCAT
TAAAACAGATGTCTACAGCTTTGGAATTGTAATAATGGAAGTTCTAACAGGATGTAGAGTAGTGTTAGATGATCCAAAACATATCCAGCT
GCGGGATCTCCTTAGAGAATTGATGGAGAAGAGAGGCCTGGATTCATGTCTCTCATTTCTAGATAAGAAAGTGCCTCCCTGCCCTCGGAA
TTTCTCTGCCAAGCTCTTCTGTTTGGCAGGCCGGTGTGCTGCAACGCGGGCAAAGTTAAGACCATCAATGGATGAAGTTTTAAATACTCT
TGAAAGTACTCAAGCCAGCTTGTATTTTGCTGAAGATCCTCCCACATCACTAAAGTCCTTCAGGTGTCCTTCTCCTCTATTCCTGGAGAA
TGTACCAAGTATTCCAGTGGAAGATGATGAAAGCCAGAATAACAATTTACTACCTTCTGATGAAGGCCTGAGGATAGACAGAATGACTCA
GAAAACTCCTTTTGAATGCAGCCAGTCTGAGGTTATGTTTCTGAGCTTGGACAAAAAGCCAGAGAGCAAGAGAAATGAGGAAGCTTGCAA
CATGCCCAGTTCTTCTTGTGAAGAAAGTTGGTTCCCAAAGTATATAGTTCCATCCCAGGACTTAAGGCCCTATAAGGTAAATATAGATCC
TTCTTCAGAAGCTCCAGGGCATTCTTGCAGGAGCAGGCCAGTGGAGAGCAGCTGTTCCTCCAAATTTTCCTGGGATGAATATGAACAGTA
CAAAAAAGAATAAATTCTACCAGAAGATAAAGAAAAAAGCAAGTATTGCATAGGCACCTGAGCATAGGTATGACCTTGGGAAGACATTGG
CTCCATAAGCAATGCCAAGAGAATGATCAATAGTGAGTTTGGGTGATGCAGATAAACAATCTGGATAATTCCATTTCTTTTTTCCCAAAC
CCTCAAACAGAGTGCCTTAAAAAATTGTTTTATCAGGATAATTGTCTCATGACCAAATCCACGCTCAATTAGAGCCATTCAAAATTCCTT
AAGATCATGGGTTCTGACTTCAGCCAAACAAAACAATCAAAACCTACCAAAAAGGGACTGGATTGTAATGTCCTCTCCATCATCCTCAGT
GTGAGTCCTCAGAGCCTCCATCTGCCAAGAACATTCAGTTGGATTCCATCGTTTGGTTTAGCTTGCTTGCACGGGTTGTAGGAAATGTCT
AATTTGTAAATGTTAATAGATACCTTTGGAAAGAATCACCTTGTTATTCTGATTGACCCCTCTTGTTTTTTGGTTAATCCCTGACTAGCC
TGCTTGTCTGAAAATGAGCCAGGTTCACCCTTAGCTACGGCATGCTCTGGGTTGAAAGGGGATTTCTTCCCAAGATCTATCCTAAACTCT
TAGGACAGTTTATCCTGTATTGACTATTATTACAGCTTTTTAAAAACAGACTTAGTGACCTATTATATCTTAAGGAGACTATGTGAAATG
TCCATCAAGTAATTTTTATTCCTGAGAAAATGGCTGGTCAAGGGCCTAGGTCAGCTTTTTGTTTAATCTACACCTTTCAACTCTGGGCCT
TCATTCCTGCTGTTTCTTGGATCTCCCTCTTTTGAAATCCTACCAATCATCAGAGCTCTACAAAACAGCCACCTCCTGGAAGCTTCCCTA
ATCTCTACAACCAGAAGTACTCCCTTTATCAGTATTTCCACAGCAATTTCTTTGTATTTCTATTTTATATTTATCACTTTCTGAATTATA
TCAAAGCTGCTTGTCTTATCTCTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCATCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCA
CCGCAAGGTCTGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAAAGGTGGGACTACAGGCGCCCGCCACTACGCCCGG
CTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTAGGCAGGATGGTCTCGATCTCCTGACCTCATGATCCGCCTGCCTGGC
CTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCAGCCTTCATCTCTTTTACTAGGTTGTAAACTCCCTATATTAGTTTTCTA
TTGTTTTTGTAACACATTATCACAAATTTAGTGACTTAAAGTAACATAAATTAATTATTTTGCAGTTCTGGAGGTCAGAATTCCTTAGCA
TTCTTTCTGGAGGCTGTTGGGGAGAACTCACTGCCTTGCCTTTTCCAGCTTCTAGAGGCCACCTGCCTTCTTTGGCTCATGGCCTCTTCC
TCCGTCTTCAAAGCCAGCAACGTGACATTTCAGATCTCCCTCTCTCTGTCTGTCTCACCGCATCTCTTCACTACCCTCTTCCTCTCATTC
TGGCCCTTCTGCATGTCTTTTATAAAGACCTTTGTGATTTCACTGGGCCCACTCATATAAGCCAGGAAAATCTCTGTGTCTCAGATCCTT
AATTTAATTACACCTGCAAAGTCCGTTTTCTCGTGTAAAGTAACATATTCACAGGTTTCTGGAATTGGGACGTGGACATCTTCGGGGGAC
CATTACTCTGTCTGTCATACTCCCTGAGTGTGTAAGGGCCATCTCTTCAGAGCCTAATGTGTCATCCTACACAGAGCAGGTGTTTCCTTA
TAAATTAAGTTGAATTAAATTACCCCTATGAAGCCACATAATCAATAATTCAGCTATAATAAACATTGCCGAATAAATTAACAAAGGGAG
GATAATGACTCCTTATGATGATGGATAGAAACACTGAAGAAAACCATTTTCAGAGGATTTACTGAATTTTCCTCTCCAAGGAGCTTGTAA
TAGAAGGGTAAACCTCTAGTTTCTTGTCCAGCAGAGGAATAGGCTCATGTCTTTTGTTTTATTTTATTTTTTTGGTGAGTCAGTATGGTT
GGGTTAATCATATTCACATTAGATTCCATGTTGAAGAACAACTAATCAAAGAAGAAAATCATCAGGAATCAGGGTGAGATTAACAGACCA
AGGTCAGAAACATGGAGTTACAATTTTCCAAAAAAGCACGAAGTGAGATTAAAACCACAGTAAGTCTTAGTCTGACTGACAGGCTTTATA
CAGGCCCTCGGTAAGCAGTTGGGAGAACCCATGCCCACCACTGCTCTGTACGGTATCTGGCTGCTCAGAGCTCTCTGATTCACAAAAGAG
ATCATCAAGAATTGACTCTGTGTTAAACTGTTTTTCACTTAGAATATGGACCCCCACCAATACATTCAATGAAGGGTCATTAAGGAAGCT
CTGATTAACACCAGGCCCATGCAGTTACTCCGCACATATAATCTGTGGGTATTATGTTGATTTGAACTTGCTTAGCTGACTTAAAGCAGG
GTTTCTCAAACTGTAGTATGCATCAGAATGACTTGGAAAGCTGGTTAAAAACGCAGATTGCTGGGTCCACCCAGCTTCTGATGCAATAGG
TCTGGGGTTAGAAATTTTGCTTTCTAATGAGTTCCCAGGTGATGCTGATGCCAATGATGTGAAGCCCGCTCTTCACATCCGTGAAAATCG
CTGCCTTAAGGTGCTCTTAAATTGTTATAGATTGGTAGATCCTACCTTTCCATCACTGGTATGTTTTTTGAGAAAAGGATCCTTTCTTTT
CATTCTGTTATATTCATCCTATTACATAGGATGTTGGTTAGCACAGAGTGGGAGCTCTAGAAAGATTGTTGACCAATCATCTTATTGACT
AGACCATCTTTCTAGAGTATAACTATTTTGGACACCTCAAAGATGAAGTCAGATAAGCTGGCAGTGACCTGATTAACGTTGTGGTAAGCA
GATGCCACTGTGGCTGGGAAGTACCAAATCTTCTGTTGAGTGATTCAGTCTTCCTGACTAGATTTGCCTTCTAGTGGGTGTATTAATAAG
CGTTAGTTGATATGAATTAAATGTTGCAACTTTCTATGGGTAATAAGAGGATACCTTTATAGTTTCATGATGTGGAGACCAAGATACATA
AGAAAGCAAGAATGAGTCTCCGGGTGTTCCCTCTGATCAGCAAACATGAATTCATAATTTCATTTACTCTCATTTTTGTAATGCACTCTG
AGCAATCCTCCAGGCAGATCCTATTTACTAAGCTTCAGGCTTTTGTCCCATTTTATAATGCCCAAACACATGGAGAAAACATTTTGTTGT
TTTTAAAAACAGGTATGGGATTTCTGATATAATCAATTTTATTGACTTCTTGGGAGTTGTAATGATCTGTGACTCACTGCATAATATTGT
AGTTTTATAGGGTGGCACATCACCCTGTGTAAAACAACTTTAATGACCTGAGGACTGATGAGTACAGGAAGTGAGGTTTATCATGAGTAG
CATTTATTAAGCATCTGCTAGAATCAAAGCACTGCATTAGCTACTAAGGTACAAAGTAAGACACAGTTTAATAAGGAAGACAGGGCATCT
ACCCAAGTCAACAGTTCAGTGACATCTGTTATTTGAACCACACACCAATGCAACCGAAGTAAATGCTGAAAGGGTGAGAAGAAGGAATAG
ATTACTATGCATTTTTGAGAGGATGAAGAAGGCTTCTTGGAGAAGGTTTCTGAAAAGAGATACGGAATTAAGAGAAATAGAAAAGAGCAC
TGACGAAGCACTCAGGATGGCTATTCAAGGAATTGGGGATCCACAGCAGCTGTGCACAACCATCCCTAATGCCAGAAAAATGGGGTAAGG
GTGAAGGGAACTGGGTCTAGAGCTTTGCATGTTTTTTTCTGGTTAACCCTTAGAGTCACCCTGAAGGTGTGGATCCCATCTTATAATAAG
GTGAGGACACTGAGTCAGGAAACTAACTTGCTAAAATCAAGTCCTCCCAGTCCTCCCATCAGGTCCTTCCAGATCTGGAGGAGCCAGGAT
TTGAACTCACATTTGTCTGACTTCAAAATCCATGCTTTTTCTTGTGTTCCAAATTGCACAATGGAGTCACTGCCAGTTCAAGCTCCTATG
AAAAGGGATGGATGTGAAAAGTCATTTGTTGATTCCACAGATTTTTAGTAGGTACCATGTCTCCTGCCTTTATCACTATCCTACTCCTCT
GCTACAACTTCTCTGCTACAGGCACCCACTGCAGTTACTTGATATGAGTTAAATGAATCCATCCATCCAAACTTCCATTCATTGAATAAA
TACTTAGCAATGGCTTCCTTTGTATCAGGCACTATTCTAGGAGCTGGGGCTACAGTGCAGATGGAAACCAGCAAAGCTCACTGCCCTCAT
GGAGCTTATATGTAAGTGAATAAATCTCAGGGTGGTTCTCCTGTCATAGGTCCTGGCTCCTCTGCCAGCTCTTCCAAATGGGTTCAGAGA
GGTTTTCTCCTTGTCCTGTTGTGTAACTGATAATCCCATGGTGGACCTCACTTTGCTATTCATATGCACTAAGTAGTTTATGGTGTGCTT
TGTGGCTGGCAATTGTGACAGATTCTATTCTTCTATTGGTATGTGGTTTCTTTGGGGCATTTGTTTGGATACTGATGGCATCTTCCGGGG
GTCTGAGGCACCTACACAAACCTCAGGTCACTATCACGTGATACTGGAGTTGCCTGTTAAATTATATTTCTTCTTCCACAAAACTGCAGG
TTCCCTGAGGGAAAGGTCTATGTCCTGCTCATTTTTGGATCCCTAATGGCTGGCACAGTACCTGGTGCATAATATGGTTCAACAAATATT
TGTAAAATGAATGAATCAAATAGTCCTTCAAAGCATCTTCAGAATCAAGATTGTCATCTAGATTGCACCCGAAGTTTATCTTTCTAGTAT
TCAGAATATAATCAATCATTGCTTAAATTATTCCATTTCATCATTCTTGAATAAAAGCTACTAATTTTAAATACTAATATCTGAGATATC
TTCGAAAAGAAGATTAGTCGTTGTATGTGTTGCTTATAAATTTTCTCTATGGTGGAAAATATTCCCAAACCATGTCTAAGCAATGAAAAA
CCAGTGTTCTGGCAGGAAATAAACTGATGTTTGTTGTGTTTTGTATCTGTCTTCCCGTTCCAAATCATTTATATATACTTGATGGTCTGT
GGGCTTGACTTGCAAGTATTTTCCTGGGAGACATTTTTATTCAAAAGACCTGTATTGCCTGCCAAACCTTCATTTAAGAGACTCATTATG
GATGTCATCTGCATCATTGCAAACTTTTCTGGTCGTCTCTATAAATAGCAAGATAATATTTACAGAGTTTTACATTGGCTCTTGAATTTT
AAAATATTCTTATAGACAAACATTAATTGGAATGGGGGGTAAGGAGGTAGGAATGGCTTACTTGCGGAAATGCAGGCTCATTGTTGTGTC
TAGTAGGTGCTAGGTGCATTCACACATCTCTTAAGCTTTAAACAACCTATTGAGCCGGTTTCCATTTCCTTGATCTATTAGATTTAAAAA
AATGAAGCATAAAGGAGTTGGCTCTTGCCCTAAGTCATACTACTGATGGAATGAGAATACAAACCAAAAACACTTTATTCAAGTCCAGGA
AATATCTGCCTTGAAAAAGAATAACTTAAAAATTAAAAGTGTCCTCTATTTGAACATGAAAACAGCTAATAAAGATGTGTTATTTTATTT
TATTATTATTAATTTTGTCCTCCCATATTGGCAAAGATAAAGCAATTGACAAAAATGGAATTCTTGTTCAATACTGGCAGGAGTGAAAAT
TGGTAGAACCTTTCTAGAAGGCAATTTGGCAACATGTATGAAAACCTAAATGTTGATACACCTTTACCCAGCAGTTTGTTTAGGAATTTA
TCCTAATGAATAAAAGTTGTCCAAGTCTTCAAACATGAGCCCAAAGGTATATTTCATGATGTTTATGATATTAAAACATTGGAAACAACT
GAAACATCCTTCAGTAAAAGATGGATTAAATAAATTCCATGCAGTTGTCATTTAAAAATATTTAGATATATGTTTATTGCTATGGATATA
TGTTCCCAAAATATTATTGAATCAAAAAGTAGACTACAGGATATATGTTGAATATGAGCTCATTTATAACATTGAATATTTTAAGATAAT
GTATGTTTCATAGAGAGATCTTCACCAAATGTTAAGGATTTTTTTTTCTGGGCTGTGGTATTTGGGTGATCTTTACATTCTTCAGACTCA

>In-frame_ENST00000582809_ENST00000261233_TCGA-FD-A6TG-01A_TLK2_chr17_60679541_+_IRAK3_chr12_66620503_length(amino acids)=960AA_start in transcript=370_stop in transcript=3252
MCSVGSLSDKEVETPEKKQNDQRNRKRKAEPYETSQGKGTPRGHKISDYFEFAGGSAPGTSPGRSVPPVARSSPQHSLSNPLPRRVEQPL
YGLDGSAAKEATEEQSALPTLMSVMLAKPRLDTEQLAQRGAGLCFTFVSAQQNSPSSTGSGNTEHSCSSQKQISIQHRQTQSDLTIEKIS
ALENSKNSDLEKKEGRIDDLLRANCDLRRQIDEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFTTVRHGASF
TEQWTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKPPAMGQAPPATNEQKQRKSKTNGAENETLTLAEYHEQEEIFKLRLGHLKKEE
AEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKH
ACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILL
VNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWFHHPNILELAAYFTETEKFCLIYPYMRNGTLFDRLQCVGDTAPLPWHI
RIGILIGISKAIHYLHNVQPCSVICGSISSANILLDDQFQPKLTDFAMAHFRSHLEHQSCTINMTSSSSKHLWYMPEEYIRQGKLSIKTD
VYSFGIVIMEVLTGCRVVLDDPKHIQLRDLLRELMEKRGLDSCLSFLDKKVPPCPRNFSAKLFCLAGRCAATRAKLRPSMDEVLNTLEST
QASLYFAEDPPTSLKSFRCPSPLFLENVPSIPVEDDESQNNNLLPSDEGLRIDRMTQKTPFECSQSEVMFLSLDKKPESKRNEEACNMPS

--------------------------------------------------------------
>In-frame_ENST00000326270_ENST00000261233_TCGA-FD-A6TG-01A_TLK2_chr17_60679541_+_IRAK3_chr12_66620503_length(transcript)=9782nt_BP=2193nt
GCGGCCGCCCGGGCCCGGGCCCGCGTCGGGCGCCTGGCTCTGTACGCGAGCCCGGGGATCTGCGGCCTTCGTGCCCCCCCTCCCCCGCCC
GCCCTCTCGTGGAGCCCGGCGCCGGCGGCGGCTGCCCGGGCGGGGGGTTGCGGCGCTCAGGAGAGGCCCCGGCTCCGCCCCGGGCCTGCC
CAGGGGGAGAGCGGAGCGGTCCGCAGCCGGGTCGGGTCGGGGCCCCTCCCGGGAGGAGCGTGGAGCGGCGGCGGCGGCGGCGGCAGAAAT
GATGGAAGAATTGCATAGCCTGGACCCACGACGGCAGGAATTATTGGAGGCCAGGTTTACTGGAGTAGGTGTTAGTAAGGGACCACTTAA
TAGTGAGTCTTCCAACCAGAGCTTGTGCAGCGTCGGATCCTTGAGTGATAAAGAAGTAGAGACTCCCGAGAAAAAGCAGAATGACCAGCG
AAATCGGAAAAGAAAAGCTGAACCATATGAAACTAGCCAAGGGAAAGGCACTCCTAGGGGACATAAAATTAGTGATTACTTTGAGTTTGC
TGGGGGAAGCGCGCCAGGAACCAGCCCTGGCAGAAGTGTTCCACCAGTTGCACGATCCTCACCGCAACATTCCTTATCCAATCCCTTACC
GCGACGAGTAGAACAGCCCCTCTATGGTTTAGATGGCAGTGCTGCAAAGGAGGCAACGGAGGAGCAGTCTGCTCTGCCAACCCTCATGTC
AGTGATGCTAGCAAAACCTCGGCTTGACACAGAGCAGCTGGCGCAAAGGGGAGCTGGCCTCTGCTTCACTTTTGTTTCAGCTCAGCAAAA
CAGTCCCTCATCTACGGGATCTGGCAACACAGAGCATTCCTGCAGCTCCCAAAAACAGATCTCCATCCAGCACAGACAGACCCAGTCCGA
CCTCACAATAGAAAAAATATCTGCACTAGAAAACAGTAAGAATTCTGACTTAGAGAAGAAGGAGGGAAGAATAGATGATTTATTAAGAGC
CAACTGTGATTTGAGACGGCAGATTGATGAACAGCAAAAGATGCTAGAGAAATACAAGGAACGATTAAATAGATGTGTGACAATGAGCAA
GAAACTCCTTATAGAAAAGTCAAAACAAGAGAAGATGGCGTGTAGAGATAAGAGCATGCAAGACCGCTTGAGACTGGGCCACTTTACTAC
TGTCCGACACGGAGCCTCATTTACTGAACAGTGGACAGATGGTTATGCTTTTCAGAATCTTATCAAGCAACAGGAAAGGATAAATTCACA
GAGGGAAGAGATAGAAAGACAACGGAAAATGTTAGCAAAGCGGAAACCTCCTGCCATGGGTCAGGCCCCTCCTGCAACCAATGAGCAGAA
ACAGCGGAAAAGCAAGACCAATGGAGCTGAAAATGAAACGCCCTCTTCTGGGAATACAGAGCTAAAGGATACAGCCCCAGCCTTAGGAGC
CCACAGTTTACTTAGGTTAACGTTAGCAGAATACCATGAACAAGAAGAAATCTTCAAACTCAGATTAGGTCATCTTAAAAAGGAGGAAGC
AGAGATCCAGGCAGAGCTGGAGAGACTAGAAAGGGTTAGAAATCTACATATCAGGGAACTAAAAAGGATACATAATGAAGATAATTCACA
ATTTAAAGATCATCCAACGCTAAATGACAGATATTTGTTGTTACATCTTTTGGGTAGAGGAGGTTTCAGTGAAGTTTACAAGGCATTTGA
TCTAACAGAGCAAAGATACGTAGCTGTGAAAATTCACCAGTTAAATAAAAACTGGAGAGATGAGAAAAAGGAGAATTACCACAAGCATGC
ATGTAGGGAATACCGGATTCATAAAGAGCTGGATCATCCCAGAATAGTTAAGCTGTATGATTACTTTTCACTGGATACTGACTCGTTTTG
TACAGTATTAGAATACTGTGAGGGAAATGATCTGGACTTCTACCTGAAACAGCACAAATTAATGTCGGAGAAAGAGGCCCGGTCCATTAT
CATGCAGATTGTGAATGCTTTAAAGTACTTAAATGAAATAAAACCTCCCATCATACACTATGACCTCAAACCAGGTAATATTCTTTTAGT
AAATGGTACAGCGTGTGGAGAGATAAAAATTACAGATTTTGGTCTTTCGAAGATCATGGATGATGATAGCTACAATTCAGTGGATGGCAT
GGAGCTAACATCACAAGGTGCTGGTACTTATTGGTTTCATCACCCAAACATACTAGAGTTGGCTGCATATTTTACAGAGACTGAGAAGTT
CTGTCTGATTTATCCATACATGAGAAATGGAACACTTTTTGACAGATTGCAGTGTGTAGGTGACACGGCCCCACTCCCTTGGCACATTCG
AATCGGTATATTAATAGGAATATCCAAAGCCATTCACTACCTGCACAACGTTCAACCATGCTCGGTCATCTGTGGCAGTATATCAAGTGC
AAACATCCTTTTGGATGATCAGTTTCAACCCAAACTAACTGATTTTGCCATGGCACACTTCCGGTCCCACCTAGAACATCAGAGTTGTAC
CATAAATATGACCAGCAGCAGCAGTAAACATCTGTGGTACATGCCAGAAGAGTACATCAGACAGGGGAAACTTTCCATTAAAACAGATGT
CTACAGCTTTGGAATTGTAATAATGGAAGTTCTAACAGGATGTAGAGTAGTGTTAGATGATCCAAAACATATCCAGCTGCGGGATCTCCT
TAGAGAATTGATGGAGAAGAGAGGCCTGGATTCATGTCTCTCATTTCTAGATAAGAAAGTGCCTCCCTGCCCTCGGAATTTCTCTGCCAA
GCTCTTCTGTTTGGCAGGCCGGTGTGCTGCAACGCGGGCAAAGTTAAGACCATCAATGGATGAAGTTTTAAATACTCTTGAAAGTACTCA
AGCCAGCTTGTATTTTGCTGAAGATCCTCCCACATCACTAAAGTCCTTCAGGTGTCCTTCTCCTCTATTCCTGGAGAATGTACCAAGTAT
TCCAGTGGAAGATGATGAAAGCCAGAATAACAATTTACTACCTTCTGATGAAGGCCTGAGGATAGACAGAATGACTCAGAAAACTCCTTT
TGAATGCAGCCAGTCTGAGGTTATGTTTCTGAGCTTGGACAAAAAGCCAGAGAGCAAGAGAAATGAGGAAGCTTGCAACATGCCCAGTTC
TTCTTGTGAAGAAAGTTGGTTCCCAAAGTATATAGTTCCATCCCAGGACTTAAGGCCCTATAAGGTAAATATAGATCCTTCTTCAGAAGC
TCCAGGGCATTCTTGCAGGAGCAGGCCAGTGGAGAGCAGCTGTTCCTCCAAATTTTCCTGGGATGAATATGAACAGTACAAAAAAGAATA
AATTCTACCAGAAGATAAAGAAAAAAGCAAGTATTGCATAGGCACCTGAGCATAGGTATGACCTTGGGAAGACATTGGCTCCATAAGCAA
TGCCAAGAGAATGATCAATAGTGAGTTTGGGTGATGCAGATAAACAATCTGGATAATTCCATTTCTTTTTTCCCAAACCCTCAAACAGAG
TGCCTTAAAAAATTGTTTTATCAGGATAATTGTCTCATGACCAAATCCACGCTCAATTAGAGCCATTCAAAATTCCTTAAGATCATGGGT
TCTGACTTCAGCCAAACAAAACAATCAAAACCTACCAAAAAGGGACTGGATTGTAATGTCCTCTCCATCATCCTCAGTGTGAGTCCTCAG
AGCCTCCATCTGCCAAGAACATTCAGTTGGATTCCATCGTTTGGTTTAGCTTGCTTGCACGGGTTGTAGGAAATGTCTAATTTGTAAATG
TTAATAGATACCTTTGGAAAGAATCACCTTGTTATTCTGATTGACCCCTCTTGTTTTTTGGTTAATCCCTGACTAGCCTGCTTGTCTGAA
AATGAGCCAGGTTCACCCTTAGCTACGGCATGCTCTGGGTTGAAAGGGGATTTCTTCCCAAGATCTATCCTAAACTCTTAGGACAGTTTA
TCCTGTATTGACTATTATTACAGCTTTTTAAAAACAGACTTAGTGACCTATTATATCTTAAGGAGACTATGTGAAATGTCCATCAAGTAA
TTTTTATTCCTGAGAAAATGGCTGGTCAAGGGCCTAGGTCAGCTTTTTGTTTAATCTACACCTTTCAACTCTGGGCCTTCATTCCTGCTG
TTTCTTGGATCTCCCTCTTTTGAAATCCTACCAATCATCAGAGCTCTACAAAACAGCCACCTCCTGGAAGCTTCCCTAATCTCTACAACC
AGAAGTACTCCCTTTATCAGTATTTCCACAGCAATTTCTTTGTATTTCTATTTTATATTTATCACTTTCTGAATTATATCAAAGCTGCTT
GTCTTATCTCTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCATCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACCGCAAGGTCTG
CCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAAAGGTGGGACTACAGGCGCCCGCCACTACGCCCGGCTAATTTTTTGT
ATTTTTAGTAGAGACGGGGTTTCACCATGTTAGGCAGGATGGTCTCGATCTCCTGACCTCATGATCCGCCTGCCTGGCCTCCCAAAGTGC
TGGGATTACAGGCGTGAGCCACCGCGCCCAGCCTTCATCTCTTTTACTAGGTTGTAAACTCCCTATATTAGTTTTCTATTGTTTTTGTAA
CACATTATCACAAATTTAGTGACTTAAAGTAACATAAATTAATTATTTTGCAGTTCTGGAGGTCAGAATTCCTTAGCATTCTTTCTGGAG
GCTGTTGGGGAGAACTCACTGCCTTGCCTTTTCCAGCTTCTAGAGGCCACCTGCCTTCTTTGGCTCATGGCCTCTTCCTCCGTCTTCAAA
GCCAGCAACGTGACATTTCAGATCTCCCTCTCTCTGTCTGTCTCACCGCATCTCTTCACTACCCTCTTCCTCTCATTCTGGCCCTTCTGC
ATGTCTTTTATAAAGACCTTTGTGATTTCACTGGGCCCACTCATATAAGCCAGGAAAATCTCTGTGTCTCAGATCCTTAATTTAATTACA
CCTGCAAAGTCCGTTTTCTCGTGTAAAGTAACATATTCACAGGTTTCTGGAATTGGGACGTGGACATCTTCGGGGGACCATTACTCTGTC
TGTCATACTCCCTGAGTGTGTAAGGGCCATCTCTTCAGAGCCTAATGTGTCATCCTACACAGAGCAGGTGTTTCCTTATAAATTAAGTTG
AATTAAATTACCCCTATGAAGCCACATAATCAATAATTCAGCTATAATAAACATTGCCGAATAAATTAACAAAGGGAGGATAATGACTCC
TTATGATGATGGATAGAAACACTGAAGAAAACCATTTTCAGAGGATTTACTGAATTTTCCTCTCCAAGGAGCTTGTAATAGAAGGGTAAA
CCTCTAGTTTCTTGTCCAGCAGAGGAATAGGCTCATGTCTTTTGTTTTATTTTATTTTTTTGGTGAGTCAGTATGGTTGGGTTAATCATA
TTCACATTAGATTCCATGTTGAAGAACAACTAATCAAAGAAGAAAATCATCAGGAATCAGGGTGAGATTAACAGACCAAGGTCAGAAACA
TGGAGTTACAATTTTCCAAAAAAGCACGAAGTGAGATTAAAACCACAGTAAGTCTTAGTCTGACTGACAGGCTTTATACAGGCCCTCGGT
AAGCAGTTGGGAGAACCCATGCCCACCACTGCTCTGTACGGTATCTGGCTGCTCAGAGCTCTCTGATTCACAAAAGAGATCATCAAGAAT
TGACTCTGTGTTAAACTGTTTTTCACTTAGAATATGGACCCCCACCAATACATTCAATGAAGGGTCATTAAGGAAGCTCTGATTAACACC
AGGCCCATGCAGTTACTCCGCACATATAATCTGTGGGTATTATGTTGATTTGAACTTGCTTAGCTGACTTAAAGCAGGGTTTCTCAAACT
GTAGTATGCATCAGAATGACTTGGAAAGCTGGTTAAAAACGCAGATTGCTGGGTCCACCCAGCTTCTGATGCAATAGGTCTGGGGTTAGA
AATTTTGCTTTCTAATGAGTTCCCAGGTGATGCTGATGCCAATGATGTGAAGCCCGCTCTTCACATCCGTGAAAATCGCTGCCTTAAGGT
GCTCTTAAATTGTTATAGATTGGTAGATCCTACCTTTCCATCACTGGTATGTTTTTTGAGAAAAGGATCCTTTCTTTTCATTCTGTTATA
TTCATCCTATTACATAGGATGTTGGTTAGCACAGAGTGGGAGCTCTAGAAAGATTGTTGACCAATCATCTTATTGACTAGACCATCTTTC
TAGAGTATAACTATTTTGGACACCTCAAAGATGAAGTCAGATAAGCTGGCAGTGACCTGATTAACGTTGTGGTAAGCAGATGCCACTGTG
GCTGGGAAGTACCAAATCTTCTGTTGAGTGATTCAGTCTTCCTGACTAGATTTGCCTTCTAGTGGGTGTATTAATAAGCGTTAGTTGATA
TGAATTAAATGTTGCAACTTTCTATGGGTAATAAGAGGATACCTTTATAGTTTCATGATGTGGAGACCAAGATACATAAGAAAGCAAGAA
TGAGTCTCCGGGTGTTCCCTCTGATCAGCAAACATGAATTCATAATTTCATTTACTCTCATTTTTGTAATGCACTCTGAGCAATCCTCCA
GGCAGATCCTATTTACTAAGCTTCAGGCTTTTGTCCCATTTTATAATGCCCAAACACATGGAGAAAACATTTTGTTGTTTTTAAAAACAG
GTATGGGATTTCTGATATAATCAATTTTATTGACTTCTTGGGAGTTGTAATGATCTGTGACTCACTGCATAATATTGTAGTTTTATAGGG
TGGCACATCACCCTGTGTAAAACAACTTTAATGACCTGAGGACTGATGAGTACAGGAAGTGAGGTTTATCATGAGTAGCATTTATTAAGC
ATCTGCTAGAATCAAAGCACTGCATTAGCTACTAAGGTACAAAGTAAGACACAGTTTAATAAGGAAGACAGGGCATCTACCCAAGTCAAC
AGTTCAGTGACATCTGTTATTTGAACCACACACCAATGCAACCGAAGTAAATGCTGAAAGGGTGAGAAGAAGGAATAGATTACTATGCAT
TTTTGAGAGGATGAAGAAGGCTTCTTGGAGAAGGTTTCTGAAAAGAGATACGGAATTAAGAGAAATAGAAAAGAGCACTGACGAAGCACT
CAGGATGGCTATTCAAGGAATTGGGGATCCACAGCAGCTGTGCACAACCATCCCTAATGCCAGAAAAATGGGGTAAGGGTGAAGGGAACT
GGGTCTAGAGCTTTGCATGTTTTTTTCTGGTTAACCCTTAGAGTCACCCTGAAGGTGTGGATCCCATCTTATAATAAGGTGAGGACACTG
AGTCAGGAAACTAACTTGCTAAAATCAAGTCCTCCCAGTCCTCCCATCAGGTCCTTCCAGATCTGGAGGAGCCAGGATTTGAACTCACAT
TTGTCTGACTTCAAAATCCATGCTTTTTCTTGTGTTCCAAATTGCACAATGGAGTCACTGCCAGTTCAAGCTCCTATGAAAAGGGATGGA
TGTGAAAAGTCATTTGTTGATTCCACAGATTTTTAGTAGGTACCATGTCTCCTGCCTTTATCACTATCCTACTCCTCTGCTACAACTTCT
CTGCTACAGGCACCCACTGCAGTTACTTGATATGAGTTAAATGAATCCATCCATCCAAACTTCCATTCATTGAATAAATACTTAGCAATG
GCTTCCTTTGTATCAGGCACTATTCTAGGAGCTGGGGCTACAGTGCAGATGGAAACCAGCAAAGCTCACTGCCCTCATGGAGCTTATATG
TAAGTGAATAAATCTCAGGGTGGTTCTCCTGTCATAGGTCCTGGCTCCTCTGCCAGCTCTTCCAAATGGGTTCAGAGAGGTTTTCTCCTT
GTCCTGTTGTGTAACTGATAATCCCATGGTGGACCTCACTTTGCTATTCATATGCACTAAGTAGTTTATGGTGTGCTTTGTGGCTGGCAA
TTGTGACAGATTCTATTCTTCTATTGGTATGTGGTTTCTTTGGGGCATTTGTTTGGATACTGATGGCATCTTCCGGGGGTCTGAGGCACC
TACACAAACCTCAGGTCACTATCACGTGATACTGGAGTTGCCTGTTAAATTATATTTCTTCTTCCACAAAACTGCAGGTTCCCTGAGGGA
AAGGTCTATGTCCTGCTCATTTTTGGATCCCTAATGGCTGGCACAGTACCTGGTGCATAATATGGTTCAACAAATATTTGTAAAATGAAT
GAATCAAATAGTCCTTCAAAGCATCTTCAGAATCAAGATTGTCATCTAGATTGCACCCGAAGTTTATCTTTCTAGTATTCAGAATATAAT
CAATCATTGCTTAAATTATTCCATTTCATCATTCTTGAATAAAAGCTACTAATTTTAAATACTAATATCTGAGATATCTTCGAAAAGAAG
ATTAGTCGTTGTATGTGTTGCTTATAAATTTTCTCTATGGTGGAAAATATTCCCAAACCATGTCTAAGCAATGAAAAACCAGTGTTCTGG
CAGGAAATAAACTGATGTTTGTTGTGTTTTGTATCTGTCTTCCCGTTCCAAATCATTTATATATACTTGATGGTCTGTGGGCTTGACTTG
CAAGTATTTTCCTGGGAGACATTTTTATTCAAAAGACCTGTATTGCCTGCCAAACCTTCATTTAAGAGACTCATTATGGATGTCATCTGC
ATCATTGCAAACTTTTCTGGTCGTCTCTATAAATAGCAAGATAATATTTACAGAGTTTTACATTGGCTCTTGAATTTTAAAATATTCTTA
TAGACAAACATTAATTGGAATGGGGGGTAAGGAGGTAGGAATGGCTTACTTGCGGAAATGCAGGCTCATTGTTGTGTCTAGTAGGTGCTA
GGTGCATTCACACATCTCTTAAGCTTTAAACAACCTATTGAGCCGGTTTCCATTTCCTTGATCTATTAGATTTAAAAAAATGAAGCATAA
AGGAGTTGGCTCTTGCCCTAAGTCATACTACTGATGGAATGAGAATACAAACCAAAAACACTTTATTCAAGTCCAGGAAATATCTGCCTT
GAAAAAGAATAACTTAAAAATTAAAAGTGTCCTCTATTTGAACATGAAAACAGCTAATAAAGATGTGTTATTTTATTTTATTATTATTAA
TTTTGTCCTCCCATATTGGCAAAGATAAAGCAATTGACAAAAATGGAATTCTTGTTCAATACTGGCAGGAGTGAAAATTGGTAGAACCTT
TCTAGAAGGCAATTTGGCAACATGTATGAAAACCTAAATGTTGATACACCTTTACCCAGCAGTTTGTTTAGGAATTTATCCTAATGAATA
AAAGTTGTCCAAGTCTTCAAACATGAGCCCAAAGGTATATTTCATGATGTTTATGATATTAAAACATTGGAAACAACTGAAACATCCTTC
AGTAAAAGATGGATTAAATAAATTCCATGCAGTTGTCATTTAAAAATATTTAGATATATGTTTATTGCTATGGATATATGTTCCCAAAAT
ATTATTGAATCAAAAAGTAGACTACAGGATATATGTTGAATATGAGCTCATTTATAACATTGAATATTTTAAGATAATGTATGTTTCATA
GAGAGATCTTCACCAAATGTTAAGGATTTTTTTTTCTGGGCTGTGGTATTTGGGTGATCTTTACATTCTTCAGACTCATGTGTGTTTGAA

>In-frame_ENST00000326270_ENST00000261233_TCGA-FD-A6TG-01A_TLK2_chr17_60679541_+_IRAK3_chr12_66620503_length(amino acids)=1069AA_start in transcript=121_stop in transcript=3330
MPGRGVAALRRGPGSAPGLPRGRAERSAAGSGRGPSREERGAAAAAAAEMMEELHSLDPRRQELLEARFTGVGVSKGPLNSESSNQSLCS
VGSLSDKEVETPEKKQNDQRNRKRKAEPYETSQGKGTPRGHKISDYFEFAGGSAPGTSPGRSVPPVARSSPQHSLSNPLPRRVEQPLYGL
DGSAAKEATEEQSALPTLMSVMLAKPRLDTEQLAQRGAGLCFTFVSAQQNSPSSTGSGNTEHSCSSQKQISIQHRQTQSDLTIEKISALE
NSKNSDLEKKEGRIDDLLRANCDLRRQIDEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFTTVRHGASFTEQ
WTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKPPAMGQAPPATNEQKQRKSKTNGAENETPSSGNTELKDTAPALGAHSLLRLTLAE
YHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVK
IHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYL
NEIKPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWFHHPNILELAAYFTETEKFCLIYPYMRNG
TLFDRLQCVGDTAPLPWHIRIGILIGISKAIHYLHNVQPCSVICGSISSANILLDDQFQPKLTDFAMAHFRSHLEHQSCTINMTSSSSKH
LWYMPEEYIRQGKLSIKTDVYSFGIVIMEVLTGCRVVLDDPKHIQLRDLLRELMEKRGLDSCLSFLDKKVPPCPRNFSAKLFCLAGRCAA
TRAKLRPSMDEVLNTLESTQASLYFAEDPPTSLKSFRCPSPLFLENVPSIPVEDDESQNNNLLPSDEGLRIDRMTQKTPFECSQSEVMFL

--------------------------------------------------------------
>In-frame_ENST00000346027_ENST00000261233_TCGA-FD-A6TG-01A_TLK2_chr17_60679541_+_IRAK3_chr12_66620503_length(transcript)=9719nt_BP=2130nt
GCGGCCGCCCGGGCCCGGGCCCGCGTCGGGCGCCTGGCTCTGTACGCGAGCCCGGGGATCTGCGGCCTTCGTGCCCCCCCTCCCCCGCCC
GCCCTCTCGTGGAGCCCGGCGCCGGCGGCGGCTGCCCGGGCGGGGGGTTGCGGCGCTCAGGAGAGGCCCCGGCTCCGCCCCGGGCCTGCC
CAGGGGGAGAGCGGAGCGGTCCGCAGCCGGGTCGGGTCGGGGCCCCTCCCGGGAGGAGCGTGGAGCGGCGGCGGCGGCGGCGGCAGCAGA
AATGATGGAAGAATTGCATAGCCTGGACCCACGACGGCAGGAATTATTGGAGGCCAGGTTTACTGGAGTAGGTGTTAGTAAGGGACCACT
TAATAGTGAGTCTTCCAACCAGAGCTTGTGCAGCGTCGGATCCTTGAGTGATAAAGAAGTAGAGACTCCCGAGAAAAAGCAGAATGACCA
GCGAAATCGGAAAAGAAAAGCTGAACCATATGAAACTAGCCAAGGGAAAGGCACTCCTAGGGGACATAAAATTAGTGATTACTTTGAGTT
TGCTGGGGGAAGCGCGCCAGGAACCAGCCCTGGCAGAAGTGTTCCACCAGTTGCACGATCCTCACCGCAACATTCCTTATCCAATCCCTT
ACCGCGACGAGTAGAACAGCCCCTCTATGGTTTAGATGGCAGTGCTGCAAAGGAGGCAACGGAGGAGCAGTCTGCTCTGCCAACCCTCAT
GTCAGTGATGCTAGCAAAACCTCGGCTTGACACAGAGCAGCTGGCGCAAAGGGGAGCTGGCCTCTGCTTCACTTTTGTTTCAGCTCAGCA
AAACAGTCCCTCATCTACGGGATCTGGCAACACAGAGCATTCCTGCAGCTCCCAAAAACAGATCTCCATCCAGCACAGACAGACCCAGTC
CGACCTCACAATAGAAAAAATATCTGCACTAGAAAACAGTAAGAATTCTGACTTAGAGAAGAAGGAGGGAAGAATAGATGATTTATTAAG
AGCCAACTGTGATTTGAGACGGCAGATTGATGAACAGCAAAAGATGCTAGAGAAATACAAGGAACGATTAAATAGATGTGTGACAATGAG
CAAGAAACTCCTTATAGAAAAGTCAAAACAAGAGAAGATGGCGTGTAGAGATAAGAGCATGCAAGACCGCTTGAGACTGGGCCACTTTAC
TACTGTCCGACACGGAGCCTCATTTACTGAACAGTGGACAGATGGTTATGCTTTTCAGAATCTTATCAAGCAACAGGAAAGGATAAATTC
ACAGAGGGAAGAGATAGAAAGACAACGGAAAATGTTAGCAAAGCGGAAACCTCCTGCCATGGGTCAGGCCCCTCCTGCAACCAATGAGCA
GAAACAGCGGAAAAGCAAGACCAATGGAGCTGAAAATGAAACGTTAACGTTAGCAGAATACCATGAACAAGAAGAAATCTTCAAACTCAG
ATTAGGTCATCTTAAAAAGGAGGAAGCAGAGATCCAGGCAGAGCTGGAGAGACTAGAAAGGGTTAGAAATCTACATATCAGGGAACTAAA
AAGGATACATAATGAAGATAATTCACAATTTAAAGATCATCCAACGCTAAATGACAGATATTTGTTGTTACATCTTTTGGGTAGAGGAGG
TTTCAGTGAAGTTTACAAGGCATTTGATCTAACAGAGCAAAGATACGTAGCTGTGAAAATTCACCAGTTAAATAAAAACTGGAGAGATGA
GAAAAAGGAGAATTACCACAAGCATGCATGTAGGGAATACCGGATTCATAAAGAGCTGGATCATCCCAGAATAGTTAAGCTGTATGATTA
CTTTTCACTGGATACTGACTCGTTTTGTACAGTATTAGAATACTGTGAGGGAAATGATCTGGACTTCTACCTGAAACAGCACAAATTAAT
GTCGGAGAAAGAGGCCCGGTCCATTATCATGCAGATTGTGAATGCTTTAAAGTACTTAAATGAAATAAAACCTCCCATCATACACTATGA
CCTCAAACCAGGTAATATTCTTTTAGTAAATGGTACAGCGTGTGGAGAGATAAAAATTACAGATTTTGGTCTTTCGAAGATCATGGATGA
TGATAGCTACAATTCAGTGGATGGCATGGAGCTAACATCACAAGGTGCTGGTACTTATTGGTTTCATCACCCAAACATACTAGAGTTGGC
TGCATATTTTACAGAGACTGAGAAGTTCTGTCTGATTTATCCATACATGAGAAATGGAACACTTTTTGACAGATTGCAGTGTGTAGGTGA
CACGGCCCCACTCCCTTGGCACATTCGAATCGGTATATTAATAGGAATATCCAAAGCCATTCACTACCTGCACAACGTTCAACCATGCTC
GGTCATCTGTGGCAGTATATCAAGTGCAAACATCCTTTTGGATGATCAGTTTCAACCCAAACTAACTGATTTTGCCATGGCACACTTCCG
GTCCCACCTAGAACATCAGAGTTGTACCATAAATATGACCAGCAGCAGCAGTAAACATCTGTGGTACATGCCAGAAGAGTACATCAGACA
GGGGAAACTTTCCATTAAAACAGATGTCTACAGCTTTGGAATTGTAATAATGGAAGTTCTAACAGGATGTAGAGTAGTGTTAGATGATCC
AAAACATATCCAGCTGCGGGATCTCCTTAGAGAATTGATGGAGAAGAGAGGCCTGGATTCATGTCTCTCATTTCTAGATAAGAAAGTGCC
TCCCTGCCCTCGGAATTTCTCTGCCAAGCTCTTCTGTTTGGCAGGCCGGTGTGCTGCAACGCGGGCAAAGTTAAGACCATCAATGGATGA
AGTTTTAAATACTCTTGAAAGTACTCAAGCCAGCTTGTATTTTGCTGAAGATCCTCCCACATCACTAAAGTCCTTCAGGTGTCCTTCTCC
TCTATTCCTGGAGAATGTACCAAGTATTCCAGTGGAAGATGATGAAAGCCAGAATAACAATTTACTACCTTCTGATGAAGGCCTGAGGAT
AGACAGAATGACTCAGAAAACTCCTTTTGAATGCAGCCAGTCTGAGGTTATGTTTCTGAGCTTGGACAAAAAGCCAGAGAGCAAGAGAAA
TGAGGAAGCTTGCAACATGCCCAGTTCTTCTTGTGAAGAAAGTTGGTTCCCAAAGTATATAGTTCCATCCCAGGACTTAAGGCCCTATAA
GGTAAATATAGATCCTTCTTCAGAAGCTCCAGGGCATTCTTGCAGGAGCAGGCCAGTGGAGAGCAGCTGTTCCTCCAAATTTTCCTGGGA
TGAATATGAACAGTACAAAAAAGAATAAATTCTACCAGAAGATAAAGAAAAAAGCAAGTATTGCATAGGCACCTGAGCATAGGTATGACC
TTGGGAAGACATTGGCTCCATAAGCAATGCCAAGAGAATGATCAATAGTGAGTTTGGGTGATGCAGATAAACAATCTGGATAATTCCATT
TCTTTTTTCCCAAACCCTCAAACAGAGTGCCTTAAAAAATTGTTTTATCAGGATAATTGTCTCATGACCAAATCCACGCTCAATTAGAGC
CATTCAAAATTCCTTAAGATCATGGGTTCTGACTTCAGCCAAACAAAACAATCAAAACCTACCAAAAAGGGACTGGATTGTAATGTCCTC
TCCATCATCCTCAGTGTGAGTCCTCAGAGCCTCCATCTGCCAAGAACATTCAGTTGGATTCCATCGTTTGGTTTAGCTTGCTTGCACGGG
TTGTAGGAAATGTCTAATTTGTAAATGTTAATAGATACCTTTGGAAAGAATCACCTTGTTATTCTGATTGACCCCTCTTGTTTTTTGGTT
AATCCCTGACTAGCCTGCTTGTCTGAAAATGAGCCAGGTTCACCCTTAGCTACGGCATGCTCTGGGTTGAAAGGGGATTTCTTCCCAAGA
TCTATCCTAAACTCTTAGGACAGTTTATCCTGTATTGACTATTATTACAGCTTTTTAAAAACAGACTTAGTGACCTATTATATCTTAAGG
AGACTATGTGAAATGTCCATCAAGTAATTTTTATTCCTGAGAAAATGGCTGGTCAAGGGCCTAGGTCAGCTTTTTGTTTAATCTACACCT
TTCAACTCTGGGCCTTCATTCCTGCTGTTTCTTGGATCTCCCTCTTTTGAAATCCTACCAATCATCAGAGCTCTACAAAACAGCCACCTC
CTGGAAGCTTCCCTAATCTCTACAACCAGAAGTACTCCCTTTATCAGTATTTCCACAGCAATTTCTTTGTATTTCTATTTTATATTTATC
ACTTTCTGAATTATATCAAAGCTGCTTGTCTTATCTCTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCATCCAGGCTGGAGTGCAGTGG
CACAATCTCGGCTCACCGCAAGGTCTGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAAAGGTGGGACTACAGGCGCC
CGCCACTACGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTAGGCAGGATGGTCTCGATCTCCTGACCTCATG
ATCCGCCTGCCTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCAGCCTTCATCTCTTTTACTAGGTTGTAAACTCCC
TATATTAGTTTTCTATTGTTTTTGTAACACATTATCACAAATTTAGTGACTTAAAGTAACATAAATTAATTATTTTGCAGTTCTGGAGGT
CAGAATTCCTTAGCATTCTTTCTGGAGGCTGTTGGGGAGAACTCACTGCCTTGCCTTTTCCAGCTTCTAGAGGCCACCTGCCTTCTTTGG
CTCATGGCCTCTTCCTCCGTCTTCAAAGCCAGCAACGTGACATTTCAGATCTCCCTCTCTCTGTCTGTCTCACCGCATCTCTTCACTACC
CTCTTCCTCTCATTCTGGCCCTTCTGCATGTCTTTTATAAAGACCTTTGTGATTTCACTGGGCCCACTCATATAAGCCAGGAAAATCTCT
GTGTCTCAGATCCTTAATTTAATTACACCTGCAAAGTCCGTTTTCTCGTGTAAAGTAACATATTCACAGGTTTCTGGAATTGGGACGTGG
ACATCTTCGGGGGACCATTACTCTGTCTGTCATACTCCCTGAGTGTGTAAGGGCCATCTCTTCAGAGCCTAATGTGTCATCCTACACAGA
GCAGGTGTTTCCTTATAAATTAAGTTGAATTAAATTACCCCTATGAAGCCACATAATCAATAATTCAGCTATAATAAACATTGCCGAATA
AATTAACAAAGGGAGGATAATGACTCCTTATGATGATGGATAGAAACACTGAAGAAAACCATTTTCAGAGGATTTACTGAATTTTCCTCT
CCAAGGAGCTTGTAATAGAAGGGTAAACCTCTAGTTTCTTGTCCAGCAGAGGAATAGGCTCATGTCTTTTGTTTTATTTTATTTTTTTGG
TGAGTCAGTATGGTTGGGTTAATCATATTCACATTAGATTCCATGTTGAAGAACAACTAATCAAAGAAGAAAATCATCAGGAATCAGGGT
GAGATTAACAGACCAAGGTCAGAAACATGGAGTTACAATTTTCCAAAAAAGCACGAAGTGAGATTAAAACCACAGTAAGTCTTAGTCTGA
CTGACAGGCTTTATACAGGCCCTCGGTAAGCAGTTGGGAGAACCCATGCCCACCACTGCTCTGTACGGTATCTGGCTGCTCAGAGCTCTC
TGATTCACAAAAGAGATCATCAAGAATTGACTCTGTGTTAAACTGTTTTTCACTTAGAATATGGACCCCCACCAATACATTCAATGAAGG
GTCATTAAGGAAGCTCTGATTAACACCAGGCCCATGCAGTTACTCCGCACATATAATCTGTGGGTATTATGTTGATTTGAACTTGCTTAG
CTGACTTAAAGCAGGGTTTCTCAAACTGTAGTATGCATCAGAATGACTTGGAAAGCTGGTTAAAAACGCAGATTGCTGGGTCCACCCAGC
TTCTGATGCAATAGGTCTGGGGTTAGAAATTTTGCTTTCTAATGAGTTCCCAGGTGATGCTGATGCCAATGATGTGAAGCCCGCTCTTCA
CATCCGTGAAAATCGCTGCCTTAAGGTGCTCTTAAATTGTTATAGATTGGTAGATCCTACCTTTCCATCACTGGTATGTTTTTTGAGAAA
AGGATCCTTTCTTTTCATTCTGTTATATTCATCCTATTACATAGGATGTTGGTTAGCACAGAGTGGGAGCTCTAGAAAGATTGTTGACCA
ATCATCTTATTGACTAGACCATCTTTCTAGAGTATAACTATTTTGGACACCTCAAAGATGAAGTCAGATAAGCTGGCAGTGACCTGATTA
ACGTTGTGGTAAGCAGATGCCACTGTGGCTGGGAAGTACCAAATCTTCTGTTGAGTGATTCAGTCTTCCTGACTAGATTTGCCTTCTAGT
GGGTGTATTAATAAGCGTTAGTTGATATGAATTAAATGTTGCAACTTTCTATGGGTAATAAGAGGATACCTTTATAGTTTCATGATGTGG
AGACCAAGATACATAAGAAAGCAAGAATGAGTCTCCGGGTGTTCCCTCTGATCAGCAAACATGAATTCATAATTTCATTTACTCTCATTT
TTGTAATGCACTCTGAGCAATCCTCCAGGCAGATCCTATTTACTAAGCTTCAGGCTTTTGTCCCATTTTATAATGCCCAAACACATGGAG
AAAACATTTTGTTGTTTTTAAAAACAGGTATGGGATTTCTGATATAATCAATTTTATTGACTTCTTGGGAGTTGTAATGATCTGTGACTC
ACTGCATAATATTGTAGTTTTATAGGGTGGCACATCACCCTGTGTAAAACAACTTTAATGACCTGAGGACTGATGAGTACAGGAAGTGAG
GTTTATCATGAGTAGCATTTATTAAGCATCTGCTAGAATCAAAGCACTGCATTAGCTACTAAGGTACAAAGTAAGACACAGTTTAATAAG
GAAGACAGGGCATCTACCCAAGTCAACAGTTCAGTGACATCTGTTATTTGAACCACACACCAATGCAACCGAAGTAAATGCTGAAAGGGT
GAGAAGAAGGAATAGATTACTATGCATTTTTGAGAGGATGAAGAAGGCTTCTTGGAGAAGGTTTCTGAAAAGAGATACGGAATTAAGAGA
AATAGAAAAGAGCACTGACGAAGCACTCAGGATGGCTATTCAAGGAATTGGGGATCCACAGCAGCTGTGCACAACCATCCCTAATGCCAG
AAAAATGGGGTAAGGGTGAAGGGAACTGGGTCTAGAGCTTTGCATGTTTTTTTCTGGTTAACCCTTAGAGTCACCCTGAAGGTGTGGATC
CCATCTTATAATAAGGTGAGGACACTGAGTCAGGAAACTAACTTGCTAAAATCAAGTCCTCCCAGTCCTCCCATCAGGTCCTTCCAGATC
TGGAGGAGCCAGGATTTGAACTCACATTTGTCTGACTTCAAAATCCATGCTTTTTCTTGTGTTCCAAATTGCACAATGGAGTCACTGCCA
GTTCAAGCTCCTATGAAAAGGGATGGATGTGAAAAGTCATTTGTTGATTCCACAGATTTTTAGTAGGTACCATGTCTCCTGCCTTTATCA
CTATCCTACTCCTCTGCTACAACTTCTCTGCTACAGGCACCCACTGCAGTTACTTGATATGAGTTAAATGAATCCATCCATCCAAACTTC
CATTCATTGAATAAATACTTAGCAATGGCTTCCTTTGTATCAGGCACTATTCTAGGAGCTGGGGCTACAGTGCAGATGGAAACCAGCAAA
GCTCACTGCCCTCATGGAGCTTATATGTAAGTGAATAAATCTCAGGGTGGTTCTCCTGTCATAGGTCCTGGCTCCTCTGCCAGCTCTTCC
AAATGGGTTCAGAGAGGTTTTCTCCTTGTCCTGTTGTGTAACTGATAATCCCATGGTGGACCTCACTTTGCTATTCATATGCACTAAGTA
GTTTATGGTGTGCTTTGTGGCTGGCAATTGTGACAGATTCTATTCTTCTATTGGTATGTGGTTTCTTTGGGGCATTTGTTTGGATACTGA
TGGCATCTTCCGGGGGTCTGAGGCACCTACACAAACCTCAGGTCACTATCACGTGATACTGGAGTTGCCTGTTAAATTATATTTCTTCTT
CCACAAAACTGCAGGTTCCCTGAGGGAAAGGTCTATGTCCTGCTCATTTTTGGATCCCTAATGGCTGGCACAGTACCTGGTGCATAATAT
GGTTCAACAAATATTTGTAAAATGAATGAATCAAATAGTCCTTCAAAGCATCTTCAGAATCAAGATTGTCATCTAGATTGCACCCGAAGT
TTATCTTTCTAGTATTCAGAATATAATCAATCATTGCTTAAATTATTCCATTTCATCATTCTTGAATAAAAGCTACTAATTTTAAATACT
AATATCTGAGATATCTTCGAAAAGAAGATTAGTCGTTGTATGTGTTGCTTATAAATTTTCTCTATGGTGGAAAATATTCCCAAACCATGT
CTAAGCAATGAAAAACCAGTGTTCTGGCAGGAAATAAACTGATGTTTGTTGTGTTTTGTATCTGTCTTCCCGTTCCAAATCATTTATATA
TACTTGATGGTCTGTGGGCTTGACTTGCAAGTATTTTCCTGGGAGACATTTTTATTCAAAAGACCTGTATTGCCTGCCAAACCTTCATTT
AAGAGACTCATTATGGATGTCATCTGCATCATTGCAAACTTTTCTGGTCGTCTCTATAAATAGCAAGATAATATTTACAGAGTTTTACAT
TGGCTCTTGAATTTTAAAATATTCTTATAGACAAACATTAATTGGAATGGGGGGTAAGGAGGTAGGAATGGCTTACTTGCGGAAATGCAG
GCTCATTGTTGTGTCTAGTAGGTGCTAGGTGCATTCACACATCTCTTAAGCTTTAAACAACCTATTGAGCCGGTTTCCATTTCCTTGATC
TATTAGATTTAAAAAAATGAAGCATAAAGGAGTTGGCTCTTGCCCTAAGTCATACTACTGATGGAATGAGAATACAAACCAAAAACACTT
TATTCAAGTCCAGGAAATATCTGCCTTGAAAAAGAATAACTTAAAAATTAAAAGTGTCCTCTATTTGAACATGAAAACAGCTAATAAAGA
TGTGTTATTTTATTTTATTATTATTAATTTTGTCCTCCCATATTGGCAAAGATAAAGCAATTGACAAAAATGGAATTCTTGTTCAATACT
GGCAGGAGTGAAAATTGGTAGAACCTTTCTAGAAGGCAATTTGGCAACATGTATGAAAACCTAAATGTTGATACACCTTTACCCAGCAGT
TTGTTTAGGAATTTATCCTAATGAATAAAAGTTGTCCAAGTCTTCAAACATGAGCCCAAAGGTATATTTCATGATGTTTATGATATTAAA
ACATTGGAAACAACTGAAACATCCTTCAGTAAAAGATGGATTAAATAAATTCCATGCAGTTGTCATTTAAAAATATTTAGATATATGTTT
ATTGCTATGGATATATGTTCCCAAAATATTATTGAATCAAAAAGTAGACTACAGGATATATGTTGAATATGAGCTCATTTATAACATTGA
ATATTTTAAGATAATGTATGTTTCATAGAGAGATCTTCACCAAATGTTAAGGATTTTTTTTTCTGGGCTGTGGTATTTGGGTGATCTTTA

>In-frame_ENST00000346027_ENST00000261233_TCGA-FD-A6TG-01A_TLK2_chr17_60679541_+_IRAK3_chr12_66620503_length(amino acids)=1048AA_start in transcript=121_stop in transcript=3267
MPGRGVAALRRGPGSAPGLPRGRAERSAAGSGRGPSREERGAAAAAAAAEMMEELHSLDPRRQELLEARFTGVGVSKGPLNSESSNQSLC
SVGSLSDKEVETPEKKQNDQRNRKRKAEPYETSQGKGTPRGHKISDYFEFAGGSAPGTSPGRSVPPVARSSPQHSLSNPLPRRVEQPLYG
LDGSAAKEATEEQSALPTLMSVMLAKPRLDTEQLAQRGAGLCFTFVSAQQNSPSSTGSGNTEHSCSSQKQISIQHRQTQSDLTIEKISAL
ENSKNSDLEKKEGRIDDLLRANCDLRRQIDEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFTTVRHGASFTE
QWTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKPPAMGQAPPATNEQKQRKSKTNGAENETLTLAEYHEQEEIFKLRLGHLKKEEAE
IQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHAC
REYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILLVN
GTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWFHHPNILELAAYFTETEKFCLIYPYMRNGTLFDRLQCVGDTAPLPWHIRI
GILIGISKAIHYLHNVQPCSVICGSISSANILLDDQFQPKLTDFAMAHFRSHLEHQSCTINMTSSSSKHLWYMPEEYIRQGKLSIKTDVY
SFGIVIMEVLTGCRVVLDDPKHIQLRDLLRELMEKRGLDSCLSFLDKKVPPCPRNFSAKLFCLAGRCAATRAKLRPSMDEVLNTLESTQA
SLYFAEDPPTSLKSFRCPSPLFLENVPSIPVEDDESQNNNLLPSDEGLRIDRMTQKTPFECSQSEVMFLSLDKKPESKRNEEACNMPSSS

--------------------------------------------------------------
>In-frame_ENST00000343388_ENST00000261233_TCGA-FD-A6TG-01A_TLK2_chr17_60679541_+_IRAK3_chr12_66620503_length(transcript)=9498nt_BP=1909nt
CCGGGCGGGGGGTTGCGGCGCTCAGGAGAGGCCCCGGCTCCGCCCCGGGCCTGCCCAGGGGGAGAGCGGAGCGGTCCGCAGCCGGGTCGG
GTCGGGGCCCCTCCCGGGAGGAGCGTGGAGCGGCGGCGGCGGCGGCGGCAGCAGAAATGATGGAAGAATTGCATAGCCTGGACCCACGAC
GGCAGGAATTATTGGAGGCCAGGTTTACTGGAGTAGGTGTTAGTAAGGGACCACTTAATAGTGAGTCTTCCAACCAGAGCTTGTGCAGCG
TCGGATCCTTGAGTGATAAAGAAGTAGAGACTCCCGAGAAAAAGCAGAATGACCAGCGAAATCGGAAAAGAAAAGCTGAACCATATGAAA
CTAGCCAAGGGAAAGGCACTCCTAGGGGACATAAAATTAGTGATTACTTTGAGCGACGAGTAGAACAGCCCCTCTATGGTTTAGATGGCA
GTGCTGCAAAGGAGGCAACGGAGGAGCAGTCTGCTCTGCCAACCCTCATGTCAGTGATGCTAGCAAAACCTCGGCTTGACACAGAGCAGC
TGGCGCAAAGGGGAGCTGGCCTCTGCTTCACTTTTGTTTCAGCTCAGCAAAACAGTCCCTCATCTACGGGATCTGGCAACACAGAGCATT
CCTGCAGCTCCCAAAAACAGATCTCCATCCAGCACAGACAGACCCAGTCCGACCTCACAATAGAAAAAATATCTGCACTAGAAAACAGTA
AGAATTCTGACTTAGAGAAGAAGGAGGGAAGAATAGATGATTTATTAAGAGCCAACTGTGATTTGAGACGGCAGATTGATGAACAGCAAA
AGATGCTAGAGAAATACAAGGAACGATTAAATAGATGTGTGACAATGAGCAAGAAACTCCTTATAGAAAAGTCAAAACAAGAGAAGATGG
CGTGTAGAGATAAGAGCATGCAAGACCGCTTGAGACTGGGCCACTTTACTACTGTCCGACACGGAGCCTCATTTACTGAACAGTGGACAG
ATGGTTATGCTTTTCAGAATCTTATCAAGCAACAGGAAAGGATAAATTCACAGAGGGAAGAGATAGAAAGACAACGGAAAATGTTAGCAA
AGCGGAAACCTCCTGCCATGGGTCAGGCCCCTCCTGCAACCAATGAGCAGAAACAGCGGAAAAGCAAGACCAATGGAGCTGAAAATGAAA
CGTTAACGTTAGCAGAATACCATGAACAAGAAGAAATCTTCAAACTCAGATTAGGTCATCTTAAAAAGGAGGAAGCAGAGATCCAGGCAG
AGCTGGAGAGACTAGAAAGGGTTAGAAATCTACATATCAGGGAACTAAAAAGGATACATAATGAAGATAATTCACAATTTAAAGATCATC
CAACGCTAAATGACAGATATTTGTTGTTACATCTTTTGGGTAGAGGAGGTTTCAGTGAAGTTTACAAGGCATTTGATCTAACAGAGCAAA
GATACGTAGCTGTGAAAATTCACCAGTTAAATAAAAACTGGAGAGATGAGAAAAAGGAGAATTACCACAAGCATGCATGTAGGGAATACC
GGATTCATAAAGAGCTGGATCATCCCAGAATAGTTAAGCTGTATGATTACTTTTCACTGGATACTGACTCGTTTTGTACAGTATTAGAAT
ACTGTGAGGGAAATGATCTGGACTTCTACCTGAAACAGCACAAATTAATGTCGGAGAAAGAGGCCCGGTCCATTATCATGCAGATTGTGA
ATGCTTTAAAGTACTTAAATGAAATAAAACCTCCCATCATACACTATGACCTCAAACCAGGTAATATTCTTTTAGTAAATGGTACAGCGT
GTGGAGAGATAAAAATTACAGATTTTGGTCTTTCGAAGATCATGGATGATGATAGCTACAATTCAGTGGATGGCATGGAGCTAACATCAC
AAGGTGCTGGTACTTATTGGTTTCATCACCCAAACATACTAGAGTTGGCTGCATATTTTACAGAGACTGAGAAGTTCTGTCTGATTTATC
CATACATGAGAAATGGAACACTTTTTGACAGATTGCAGTGTGTAGGTGACACGGCCCCACTCCCTTGGCACATTCGAATCGGTATATTAA
TAGGAATATCCAAAGCCATTCACTACCTGCACAACGTTCAACCATGCTCGGTCATCTGTGGCAGTATATCAAGTGCAAACATCCTTTTGG
ATGATCAGTTTCAACCCAAACTAACTGATTTTGCCATGGCACACTTCCGGTCCCACCTAGAACATCAGAGTTGTACCATAAATATGACCA
GCAGCAGCAGTAAACATCTGTGGTACATGCCAGAAGAGTACATCAGACAGGGGAAACTTTCCATTAAAACAGATGTCTACAGCTTTGGAA
TTGTAATAATGGAAGTTCTAACAGGATGTAGAGTAGTGTTAGATGATCCAAAACATATCCAGCTGCGGGATCTCCTTAGAGAATTGATGG
AGAAGAGAGGCCTGGATTCATGTCTCTCATTTCTAGATAAGAAAGTGCCTCCCTGCCCTCGGAATTTCTCTGCCAAGCTCTTCTGTTTGG
CAGGCCGGTGTGCTGCAACGCGGGCAAAGTTAAGACCATCAATGGATGAAGTTTTAAATACTCTTGAAAGTACTCAAGCCAGCTTGTATT
TTGCTGAAGATCCTCCCACATCACTAAAGTCCTTCAGGTGTCCTTCTCCTCTATTCCTGGAGAATGTACCAAGTATTCCAGTGGAAGATG
ATGAAAGCCAGAATAACAATTTACTACCTTCTGATGAAGGCCTGAGGATAGACAGAATGACTCAGAAAACTCCTTTTGAATGCAGCCAGT
CTGAGGTTATGTTTCTGAGCTTGGACAAAAAGCCAGAGAGCAAGAGAAATGAGGAAGCTTGCAACATGCCCAGTTCTTCTTGTGAAGAAA
GTTGGTTCCCAAAGTATATAGTTCCATCCCAGGACTTAAGGCCCTATAAGGTAAATATAGATCCTTCTTCAGAAGCTCCAGGGCATTCTT
GCAGGAGCAGGCCAGTGGAGAGCAGCTGTTCCTCCAAATTTTCCTGGGATGAATATGAACAGTACAAAAAAGAATAAATTCTACCAGAAG
ATAAAGAAAAAAGCAAGTATTGCATAGGCACCTGAGCATAGGTATGACCTTGGGAAGACATTGGCTCCATAAGCAATGCCAAGAGAATGA
TCAATAGTGAGTTTGGGTGATGCAGATAAACAATCTGGATAATTCCATTTCTTTTTTCCCAAACCCTCAAACAGAGTGCCTTAAAAAATT
GTTTTATCAGGATAATTGTCTCATGACCAAATCCACGCTCAATTAGAGCCATTCAAAATTCCTTAAGATCATGGGTTCTGACTTCAGCCA
AACAAAACAATCAAAACCTACCAAAAAGGGACTGGATTGTAATGTCCTCTCCATCATCCTCAGTGTGAGTCCTCAGAGCCTCCATCTGCC
AAGAACATTCAGTTGGATTCCATCGTTTGGTTTAGCTTGCTTGCACGGGTTGTAGGAAATGTCTAATTTGTAAATGTTAATAGATACCTT
TGGAAAGAATCACCTTGTTATTCTGATTGACCCCTCTTGTTTTTTGGTTAATCCCTGACTAGCCTGCTTGTCTGAAAATGAGCCAGGTTC
ACCCTTAGCTACGGCATGCTCTGGGTTGAAAGGGGATTTCTTCCCAAGATCTATCCTAAACTCTTAGGACAGTTTATCCTGTATTGACTA
TTATTACAGCTTTTTAAAAACAGACTTAGTGACCTATTATATCTTAAGGAGACTATGTGAAATGTCCATCAAGTAATTTTTATTCCTGAG
AAAATGGCTGGTCAAGGGCCTAGGTCAGCTTTTTGTTTAATCTACACCTTTCAACTCTGGGCCTTCATTCCTGCTGTTTCTTGGATCTCC
CTCTTTTGAAATCCTACCAATCATCAGAGCTCTACAAAACAGCCACCTCCTGGAAGCTTCCCTAATCTCTACAACCAGAAGTACTCCCTT
TATCAGTATTTCCACAGCAATTTCTTTGTATTTCTATTTTATATTTATCACTTTCTGAATTATATCAAAGCTGCTTGTCTTATCTCTTTT
TTTTTTTGAGACGGAGTCTCGCTCTGTCATCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACCGCAAGGTCTGCCTCCCGGGTTCAC
GCCATTCTCCTGCCTCAGCCTCCCGAGTAAAGGTGGGACTACAGGCGCCCGCCACTACGCCCGGCTAATTTTTTGTATTTTTAGTAGAGA
CGGGGTTTCACCATGTTAGGCAGGATGGTCTCGATCTCCTGACCTCATGATCCGCCTGCCTGGCCTCCCAAAGTGCTGGGATTACAGGCG
TGAGCCACCGCGCCCAGCCTTCATCTCTTTTACTAGGTTGTAAACTCCCTATATTAGTTTTCTATTGTTTTTGTAACACATTATCACAAA
TTTAGTGACTTAAAGTAACATAAATTAATTATTTTGCAGTTCTGGAGGTCAGAATTCCTTAGCATTCTTTCTGGAGGCTGTTGGGGAGAA
CTCACTGCCTTGCCTTTTCCAGCTTCTAGAGGCCACCTGCCTTCTTTGGCTCATGGCCTCTTCCTCCGTCTTCAAAGCCAGCAACGTGAC
ATTTCAGATCTCCCTCTCTCTGTCTGTCTCACCGCATCTCTTCACTACCCTCTTCCTCTCATTCTGGCCCTTCTGCATGTCTTTTATAAA
GACCTTTGTGATTTCACTGGGCCCACTCATATAAGCCAGGAAAATCTCTGTGTCTCAGATCCTTAATTTAATTACACCTGCAAAGTCCGT
TTTCTCGTGTAAAGTAACATATTCACAGGTTTCTGGAATTGGGACGTGGACATCTTCGGGGGACCATTACTCTGTCTGTCATACTCCCTG
AGTGTGTAAGGGCCATCTCTTCAGAGCCTAATGTGTCATCCTACACAGAGCAGGTGTTTCCTTATAAATTAAGTTGAATTAAATTACCCC
TATGAAGCCACATAATCAATAATTCAGCTATAATAAACATTGCCGAATAAATTAACAAAGGGAGGATAATGACTCCTTATGATGATGGAT
AGAAACACTGAAGAAAACCATTTTCAGAGGATTTACTGAATTTTCCTCTCCAAGGAGCTTGTAATAGAAGGGTAAACCTCTAGTTTCTTG
TCCAGCAGAGGAATAGGCTCATGTCTTTTGTTTTATTTTATTTTTTTGGTGAGTCAGTATGGTTGGGTTAATCATATTCACATTAGATTC
CATGTTGAAGAACAACTAATCAAAGAAGAAAATCATCAGGAATCAGGGTGAGATTAACAGACCAAGGTCAGAAACATGGAGTTACAATTT
TCCAAAAAAGCACGAAGTGAGATTAAAACCACAGTAAGTCTTAGTCTGACTGACAGGCTTTATACAGGCCCTCGGTAAGCAGTTGGGAGA
ACCCATGCCCACCACTGCTCTGTACGGTATCTGGCTGCTCAGAGCTCTCTGATTCACAAAAGAGATCATCAAGAATTGACTCTGTGTTAA
ACTGTTTTTCACTTAGAATATGGACCCCCACCAATACATTCAATGAAGGGTCATTAAGGAAGCTCTGATTAACACCAGGCCCATGCAGTT
ACTCCGCACATATAATCTGTGGGTATTATGTTGATTTGAACTTGCTTAGCTGACTTAAAGCAGGGTTTCTCAAACTGTAGTATGCATCAG
AATGACTTGGAAAGCTGGTTAAAAACGCAGATTGCTGGGTCCACCCAGCTTCTGATGCAATAGGTCTGGGGTTAGAAATTTTGCTTTCTA
ATGAGTTCCCAGGTGATGCTGATGCCAATGATGTGAAGCCCGCTCTTCACATCCGTGAAAATCGCTGCCTTAAGGTGCTCTTAAATTGTT
ATAGATTGGTAGATCCTACCTTTCCATCACTGGTATGTTTTTTGAGAAAAGGATCCTTTCTTTTCATTCTGTTATATTCATCCTATTACA
TAGGATGTTGGTTAGCACAGAGTGGGAGCTCTAGAAAGATTGTTGACCAATCATCTTATTGACTAGACCATCTTTCTAGAGTATAACTAT
TTTGGACACCTCAAAGATGAAGTCAGATAAGCTGGCAGTGACCTGATTAACGTTGTGGTAAGCAGATGCCACTGTGGCTGGGAAGTACCA
AATCTTCTGTTGAGTGATTCAGTCTTCCTGACTAGATTTGCCTTCTAGTGGGTGTATTAATAAGCGTTAGTTGATATGAATTAAATGTTG
CAACTTTCTATGGGTAATAAGAGGATACCTTTATAGTTTCATGATGTGGAGACCAAGATACATAAGAAAGCAAGAATGAGTCTCCGGGTG
TTCCCTCTGATCAGCAAACATGAATTCATAATTTCATTTACTCTCATTTTTGTAATGCACTCTGAGCAATCCTCCAGGCAGATCCTATTT
ACTAAGCTTCAGGCTTTTGTCCCATTTTATAATGCCCAAACACATGGAGAAAACATTTTGTTGTTTTTAAAAACAGGTATGGGATTTCTG
ATATAATCAATTTTATTGACTTCTTGGGAGTTGTAATGATCTGTGACTCACTGCATAATATTGTAGTTTTATAGGGTGGCACATCACCCT
GTGTAAAACAACTTTAATGACCTGAGGACTGATGAGTACAGGAAGTGAGGTTTATCATGAGTAGCATTTATTAAGCATCTGCTAGAATCA
AAGCACTGCATTAGCTACTAAGGTACAAAGTAAGACACAGTTTAATAAGGAAGACAGGGCATCTACCCAAGTCAACAGTTCAGTGACATC
TGTTATTTGAACCACACACCAATGCAACCGAAGTAAATGCTGAAAGGGTGAGAAGAAGGAATAGATTACTATGCATTTTTGAGAGGATGA
AGAAGGCTTCTTGGAGAAGGTTTCTGAAAAGAGATACGGAATTAAGAGAAATAGAAAAGAGCACTGACGAAGCACTCAGGATGGCTATTC
AAGGAATTGGGGATCCACAGCAGCTGTGCACAACCATCCCTAATGCCAGAAAAATGGGGTAAGGGTGAAGGGAACTGGGTCTAGAGCTTT
GCATGTTTTTTTCTGGTTAACCCTTAGAGTCACCCTGAAGGTGTGGATCCCATCTTATAATAAGGTGAGGACACTGAGTCAGGAAACTAA
CTTGCTAAAATCAAGTCCTCCCAGTCCTCCCATCAGGTCCTTCCAGATCTGGAGGAGCCAGGATTTGAACTCACATTTGTCTGACTTCAA
AATCCATGCTTTTTCTTGTGTTCCAAATTGCACAATGGAGTCACTGCCAGTTCAAGCTCCTATGAAAAGGGATGGATGTGAAAAGTCATT
TGTTGATTCCACAGATTTTTAGTAGGTACCATGTCTCCTGCCTTTATCACTATCCTACTCCTCTGCTACAACTTCTCTGCTACAGGCACC
CACTGCAGTTACTTGATATGAGTTAAATGAATCCATCCATCCAAACTTCCATTCATTGAATAAATACTTAGCAATGGCTTCCTTTGTATC
AGGCACTATTCTAGGAGCTGGGGCTACAGTGCAGATGGAAACCAGCAAAGCTCACTGCCCTCATGGAGCTTATATGTAAGTGAATAAATC
TCAGGGTGGTTCTCCTGTCATAGGTCCTGGCTCCTCTGCCAGCTCTTCCAAATGGGTTCAGAGAGGTTTTCTCCTTGTCCTGTTGTGTAA
CTGATAATCCCATGGTGGACCTCACTTTGCTATTCATATGCACTAAGTAGTTTATGGTGTGCTTTGTGGCTGGCAATTGTGACAGATTCT
ATTCTTCTATTGGTATGTGGTTTCTTTGGGGCATTTGTTTGGATACTGATGGCATCTTCCGGGGGTCTGAGGCACCTACACAAACCTCAG
GTCACTATCACGTGATACTGGAGTTGCCTGTTAAATTATATTTCTTCTTCCACAAAACTGCAGGTTCCCTGAGGGAAAGGTCTATGTCCT
GCTCATTTTTGGATCCCTAATGGCTGGCACAGTACCTGGTGCATAATATGGTTCAACAAATATTTGTAAAATGAATGAATCAAATAGTCC
TTCAAAGCATCTTCAGAATCAAGATTGTCATCTAGATTGCACCCGAAGTTTATCTTTCTAGTATTCAGAATATAATCAATCATTGCTTAA
ATTATTCCATTTCATCATTCTTGAATAAAAGCTACTAATTTTAAATACTAATATCTGAGATATCTTCGAAAAGAAGATTAGTCGTTGTAT
GTGTTGCTTATAAATTTTCTCTATGGTGGAAAATATTCCCAAACCATGTCTAAGCAATGAAAAACCAGTGTTCTGGCAGGAAATAAACTG
ATGTTTGTTGTGTTTTGTATCTGTCTTCCCGTTCCAAATCATTTATATATACTTGATGGTCTGTGGGCTTGACTTGCAAGTATTTTCCTG
GGAGACATTTTTATTCAAAAGACCTGTATTGCCTGCCAAACCTTCATTTAAGAGACTCATTATGGATGTCATCTGCATCATTGCAAACTT
TTCTGGTCGTCTCTATAAATAGCAAGATAATATTTACAGAGTTTTACATTGGCTCTTGAATTTTAAAATATTCTTATAGACAAACATTAA
TTGGAATGGGGGGTAAGGAGGTAGGAATGGCTTACTTGCGGAAATGCAGGCTCATTGTTGTGTCTAGTAGGTGCTAGGTGCATTCACACA
TCTCTTAAGCTTTAAACAACCTATTGAGCCGGTTTCCATTTCCTTGATCTATTAGATTTAAAAAAATGAAGCATAAAGGAGTTGGCTCTT
GCCCTAAGTCATACTACTGATGGAATGAGAATACAAACCAAAAACACTTTATTCAAGTCCAGGAAATATCTGCCTTGAAAAAGAATAACT
TAAAAATTAAAAGTGTCCTCTATTTGAACATGAAAACAGCTAATAAAGATGTGTTATTTTATTTTATTATTATTAATTTTGTCCTCCCAT
ATTGGCAAAGATAAAGCAATTGACAAAAATGGAATTCTTGTTCAATACTGGCAGGAGTGAAAATTGGTAGAACCTTTCTAGAAGGCAATT
TGGCAACATGTATGAAAACCTAAATGTTGATACACCTTTACCCAGCAGTTTGTTTAGGAATTTATCCTAATGAATAAAAGTTGTCCAAGT
CTTCAAACATGAGCCCAAAGGTATATTTCATGATGTTTATGATATTAAAACATTGGAAACAACTGAAACATCCTTCAGTAAAAGATGGAT
TAAATAAATTCCATGCAGTTGTCATTTAAAAATATTTAGATATATGTTTATTGCTATGGATATATGTTCCCAAAATATTATTGAATCAAA
AAGTAGACTACAGGATATATGTTGAATATGAGCTCATTTATAACATTGAATATTTTAAGATAATGTATGTTTCATAGAGAGATCTTCACC
AAATGTTAAGGATTTTTTTTTCTGGGCTGTGGTATTTGGGTGATCTTTACATTCTTCAGACTCATGTGTGTTTGAAACTTTTTATAATGA

>In-frame_ENST00000343388_ENST00000261233_TCGA-FD-A6TG-01A_TLK2_chr17_60679541_+_IRAK3_chr12_66620503_length(amino acids)=998AA_start in transcript=50_stop in transcript=3046
MPRGRAERSAAGSGRGPSREERGAAAAAAAAEMMEELHSLDPRRQELLEARFTGVGVSKGPLNSESSNQSLCSVGSLSDKEVETPEKKQN
DQRNRKRKAEPYETSQGKGTPRGHKISDYFERRVEQPLYGLDGSAAKEATEEQSALPTLMSVMLAKPRLDTEQLAQRGAGLCFTFVSAQQ
NSPSSTGSGNTEHSCSSQKQISIQHRQTQSDLTIEKISALENSKNSDLEKKEGRIDDLLRANCDLRRQIDEQQKMLEKYKERLNRCVTMS
KKLLIEKSKQEKMACRDKSMQDRLRLGHFTTVRHGASFTEQWTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKPPAMGQAPPATNEQ
KQRKSKTNGAENETLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGG
FSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLM
SEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWFHHPNILELA
AYFTETEKFCLIYPYMRNGTLFDRLQCVGDTAPLPWHIRIGILIGISKAIHYLHNVQPCSVICGSISSANILLDDQFQPKLTDFAMAHFR
SHLEHQSCTINMTSSSSKHLWYMPEEYIRQGKLSIKTDVYSFGIVIMEVLTGCRVVLDDPKHIQLRDLLRELMEKRGLDSCLSFLDKKVP
PCPRNFSAKLFCLAGRCAATRAKLRPSMDEVLNTLESTQASLYFAEDPPTSLKSFRCPSPLFLENVPSIPVEDDESQNNNLLPSDEGLRI
DRMTQKTPFECSQSEVMFLSLDKKPESKRNEEACNMPSSSCEESWFPKYIVPSQDLRPYKVNIDPSSEAPGHSCRSRPVESSCSSKFSWD

--------------------------------------------------------------
>In-frame_ENST00000542523_ENST00000261233_TCGA-FD-A6TG-01A_TLK2_chr17_60679541_+_IRAK3_chr12_66620503_length(transcript)=9377nt_BP=1788nt
AAGGAATTTTCTTTTTGCAGCAGAAATGATGGAAGAATTGCATAGCCTGGACCCACGACGGCAGGAATTATTGGAGGCCAGGTTTACTGG
AGTAGGTGTTAGTAAGGGACCACTTAATAGTGAGTCTTCCAACCAGAGCTTGTGCAGCGTCGGATCCTTGAGTGATAAAGAAGTAGAGAC
TCCCGAGAAAAAGCAGAATGACCAGCGAAATCGGAAAAGAAAAGCTGAACCATATGAAACTAGCCAAGGGAAAGGCACTCCTAGGGGACA
TAAAATTAGTGATTACTTTGAGCGACGAGTAGAACAGCCCCTCTATGGTTTAGATGGCAGTGCTGCAAAGGAGGCAACGGAGGAGCAGTC
TGCTCTGCCAACCCTCATGTCAGTGATGCTAGCAAAACCTCGGCTTGACACAGAGCAGCTGGCGCAAAGGGGAGCTGGCCTCTGCTTCAC
TTTTGTTTCAGCTCAGCAAAACAGTCCCTCATCTACGGGATCTGGCAACACAGAGCATTCCTGCAGCTCCCAAAAACAGATCTCCATCCA
GCACAGACAGACCCAGTCCGACCTCACAATAGAAAAAATATCTGCACTAGAAAACAGTAAGAATTCTGACTTAGAGAAGAAGGAGGGAAG
AATAGATGATTTATTAAGAGCCAACTGTGATTTGAGACGGCAGATTGATGAACAGCAAAAGATGCTAGAGAAATACAAGGAACGATTAAA
TAGATGTGTGACAATGAGCAAGAAACTCCTTATAGAAAAGTCAAAACAAGAGAAGATGGCGTGTAGAGATAAGAGCATGCAAGACCGCTT
GAGACTGGGCCACTTTACTACTGTCCGACACGGAGCCTCATTTACTGAACAGTGGACAGATGGTTATGCTTTTCAGAATCTTATCAAGCA
ACAGGAAAGGATAAATTCACAGAGGGAAGAGATAGAAAGACAACGGAAAATGTTAGCAAAGCGGAAACCTCCTGCCATGGGTCAGGCCCC
TCCTGCAACCAATGAGCAGAAACAGCGGAAAAGCAAGACCAATGGAGCTGAAAATGAAACGTTAACGTTAGCAGAATACCATGAACAAGA
AGAAATCTTCAAACTCAGATTAGGTCATCTTAAAAAGGAGGAAGCAGAGATCCAGGCAGAGCTGGAGAGACTAGAAAGGGTTAGAAATCT
ACATATCAGGGAACTAAAAAGGATACATAATGAAGATAATTCACAATTTAAAGATCATCCAACGCTAAATGACAGATATTTGTTGTTACA
TCTTTTGGGTAGAGGAGGTTTCAGTGAAGTTTACAAGGCATTTGATCTAACAGAGCAAAGATACGTAGCTGTGAAAATTCACCAGTTAAA
TAAAAACTGGAGAGATGAGAAAAAGGAGAATTACCACAAGCATGCATGTAGGGAATACCGGATTCATAAAGAGCTGGATCATCCCAGAAT
AGTTAAGCTGTATGATTACTTTTCACTGGATACTGACTCGTTTTGTACAGTATTAGAATACTGTGAGGGAAATGATCTGGACTTCTACCT
GAAACAGCACAAATTAATGTCGGAGAAAGAGGCCCGGTCCATTATCATGCAGATTGTGAATGCTTTAAAGTACTTAAATGAAATAAAACC
TCCCATCATACACTATGACCTCAAACCAGGTAATATTCTTTTAGTAAATGGTACAGCGTGTGGAGAGATAAAAATTACAGATTTTGGTCT
TTCGAAGATCATGGATGATGATAGCTACAATTCAGTGGATGGCATGGAGCTAACATCACAAGGTGCTGGTACTTATTGGTTTCATCACCC
AAACATACTAGAGTTGGCTGCATATTTTACAGAGACTGAGAAGTTCTGTCTGATTTATCCATACATGAGAAATGGAACACTTTTTGACAG
ATTGCAGTGTGTAGGTGACACGGCCCCACTCCCTTGGCACATTCGAATCGGTATATTAATAGGAATATCCAAAGCCATTCACTACCTGCA
CAACGTTCAACCATGCTCGGTCATCTGTGGCAGTATATCAAGTGCAAACATCCTTTTGGATGATCAGTTTCAACCCAAACTAACTGATTT
TGCCATGGCACACTTCCGGTCCCACCTAGAACATCAGAGTTGTACCATAAATATGACCAGCAGCAGCAGTAAACATCTGTGGTACATGCC
AGAAGAGTACATCAGACAGGGGAAACTTTCCATTAAAACAGATGTCTACAGCTTTGGAATTGTAATAATGGAAGTTCTAACAGGATGTAG
AGTAGTGTTAGATGATCCAAAACATATCCAGCTGCGGGATCTCCTTAGAGAATTGATGGAGAAGAGAGGCCTGGATTCATGTCTCTCATT
TCTAGATAAGAAAGTGCCTCCCTGCCCTCGGAATTTCTCTGCCAAGCTCTTCTGTTTGGCAGGCCGGTGTGCTGCAACGCGGGCAAAGTT
AAGACCATCAATGGATGAAGTTTTAAATACTCTTGAAAGTACTCAAGCCAGCTTGTATTTTGCTGAAGATCCTCCCACATCACTAAAGTC
CTTCAGGTGTCCTTCTCCTCTATTCCTGGAGAATGTACCAAGTATTCCAGTGGAAGATGATGAAAGCCAGAATAACAATTTACTACCTTC
TGATGAAGGCCTGAGGATAGACAGAATGACTCAGAAAACTCCTTTTGAATGCAGCCAGTCTGAGGTTATGTTTCTGAGCTTGGACAAAAA
GCCAGAGAGCAAGAGAAATGAGGAAGCTTGCAACATGCCCAGTTCTTCTTGTGAAGAAAGTTGGTTCCCAAAGTATATAGTTCCATCCCA
GGACTTAAGGCCCTATAAGGTAAATATAGATCCTTCTTCAGAAGCTCCAGGGCATTCTTGCAGGAGCAGGCCAGTGGAGAGCAGCTGTTC
CTCCAAATTTTCCTGGGATGAATATGAACAGTACAAAAAAGAATAAATTCTACCAGAAGATAAAGAAAAAAGCAAGTATTGCATAGGCAC
CTGAGCATAGGTATGACCTTGGGAAGACATTGGCTCCATAAGCAATGCCAAGAGAATGATCAATAGTGAGTTTGGGTGATGCAGATAAAC
AATCTGGATAATTCCATTTCTTTTTTCCCAAACCCTCAAACAGAGTGCCTTAAAAAATTGTTTTATCAGGATAATTGTCTCATGACCAAA
TCCACGCTCAATTAGAGCCATTCAAAATTCCTTAAGATCATGGGTTCTGACTTCAGCCAAACAAAACAATCAAAACCTACCAAAAAGGGA
CTGGATTGTAATGTCCTCTCCATCATCCTCAGTGTGAGTCCTCAGAGCCTCCATCTGCCAAGAACATTCAGTTGGATTCCATCGTTTGGT
TTAGCTTGCTTGCACGGGTTGTAGGAAATGTCTAATTTGTAAATGTTAATAGATACCTTTGGAAAGAATCACCTTGTTATTCTGATTGAC
CCCTCTTGTTTTTTGGTTAATCCCTGACTAGCCTGCTTGTCTGAAAATGAGCCAGGTTCACCCTTAGCTACGGCATGCTCTGGGTTGAAA
GGGGATTTCTTCCCAAGATCTATCCTAAACTCTTAGGACAGTTTATCCTGTATTGACTATTATTACAGCTTTTTAAAAACAGACTTAGTG
ACCTATTATATCTTAAGGAGACTATGTGAAATGTCCATCAAGTAATTTTTATTCCTGAGAAAATGGCTGGTCAAGGGCCTAGGTCAGCTT
TTTGTTTAATCTACACCTTTCAACTCTGGGCCTTCATTCCTGCTGTTTCTTGGATCTCCCTCTTTTGAAATCCTACCAATCATCAGAGCT
CTACAAAACAGCCACCTCCTGGAAGCTTCCCTAATCTCTACAACCAGAAGTACTCCCTTTATCAGTATTTCCACAGCAATTTCTTTGTAT
TTCTATTTTATATTTATCACTTTCTGAATTATATCAAAGCTGCTTGTCTTATCTCTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCATC
CAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACCGCAAGGTCTGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAAA
GGTGGGACTACAGGCGCCCGCCACTACGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTAGGCAGGATGGTCT
CGATCTCCTGACCTCATGATCCGCCTGCCTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCAGCCTTCATCTCTTTT
ACTAGGTTGTAAACTCCCTATATTAGTTTTCTATTGTTTTTGTAACACATTATCACAAATTTAGTGACTTAAAGTAACATAAATTAATTA
TTTTGCAGTTCTGGAGGTCAGAATTCCTTAGCATTCTTTCTGGAGGCTGTTGGGGAGAACTCACTGCCTTGCCTTTTCCAGCTTCTAGAG
GCCACCTGCCTTCTTTGGCTCATGGCCTCTTCCTCCGTCTTCAAAGCCAGCAACGTGACATTTCAGATCTCCCTCTCTCTGTCTGTCTCA
CCGCATCTCTTCACTACCCTCTTCCTCTCATTCTGGCCCTTCTGCATGTCTTTTATAAAGACCTTTGTGATTTCACTGGGCCCACTCATA
TAAGCCAGGAAAATCTCTGTGTCTCAGATCCTTAATTTAATTACACCTGCAAAGTCCGTTTTCTCGTGTAAAGTAACATATTCACAGGTT
TCTGGAATTGGGACGTGGACATCTTCGGGGGACCATTACTCTGTCTGTCATACTCCCTGAGTGTGTAAGGGCCATCTCTTCAGAGCCTAA
TGTGTCATCCTACACAGAGCAGGTGTTTCCTTATAAATTAAGTTGAATTAAATTACCCCTATGAAGCCACATAATCAATAATTCAGCTAT
AATAAACATTGCCGAATAAATTAACAAAGGGAGGATAATGACTCCTTATGATGATGGATAGAAACACTGAAGAAAACCATTTTCAGAGGA
TTTACTGAATTTTCCTCTCCAAGGAGCTTGTAATAGAAGGGTAAACCTCTAGTTTCTTGTCCAGCAGAGGAATAGGCTCATGTCTTTTGT
TTTATTTTATTTTTTTGGTGAGTCAGTATGGTTGGGTTAATCATATTCACATTAGATTCCATGTTGAAGAACAACTAATCAAAGAAGAAA
ATCATCAGGAATCAGGGTGAGATTAACAGACCAAGGTCAGAAACATGGAGTTACAATTTTCCAAAAAAGCACGAAGTGAGATTAAAACCA
CAGTAAGTCTTAGTCTGACTGACAGGCTTTATACAGGCCCTCGGTAAGCAGTTGGGAGAACCCATGCCCACCACTGCTCTGTACGGTATC
TGGCTGCTCAGAGCTCTCTGATTCACAAAAGAGATCATCAAGAATTGACTCTGTGTTAAACTGTTTTTCACTTAGAATATGGACCCCCAC
CAATACATTCAATGAAGGGTCATTAAGGAAGCTCTGATTAACACCAGGCCCATGCAGTTACTCCGCACATATAATCTGTGGGTATTATGT
TGATTTGAACTTGCTTAGCTGACTTAAAGCAGGGTTTCTCAAACTGTAGTATGCATCAGAATGACTTGGAAAGCTGGTTAAAAACGCAGA
TTGCTGGGTCCACCCAGCTTCTGATGCAATAGGTCTGGGGTTAGAAATTTTGCTTTCTAATGAGTTCCCAGGTGATGCTGATGCCAATGA
TGTGAAGCCCGCTCTTCACATCCGTGAAAATCGCTGCCTTAAGGTGCTCTTAAATTGTTATAGATTGGTAGATCCTACCTTTCCATCACT
GGTATGTTTTTTGAGAAAAGGATCCTTTCTTTTCATTCTGTTATATTCATCCTATTACATAGGATGTTGGTTAGCACAGAGTGGGAGCTC
TAGAAAGATTGTTGACCAATCATCTTATTGACTAGACCATCTTTCTAGAGTATAACTATTTTGGACACCTCAAAGATGAAGTCAGATAAG
CTGGCAGTGACCTGATTAACGTTGTGGTAAGCAGATGCCACTGTGGCTGGGAAGTACCAAATCTTCTGTTGAGTGATTCAGTCTTCCTGA
CTAGATTTGCCTTCTAGTGGGTGTATTAATAAGCGTTAGTTGATATGAATTAAATGTTGCAACTTTCTATGGGTAATAAGAGGATACCTT
TATAGTTTCATGATGTGGAGACCAAGATACATAAGAAAGCAAGAATGAGTCTCCGGGTGTTCCCTCTGATCAGCAAACATGAATTCATAA
TTTCATTTACTCTCATTTTTGTAATGCACTCTGAGCAATCCTCCAGGCAGATCCTATTTACTAAGCTTCAGGCTTTTGTCCCATTTTATA
ATGCCCAAACACATGGAGAAAACATTTTGTTGTTTTTAAAAACAGGTATGGGATTTCTGATATAATCAATTTTATTGACTTCTTGGGAGT
TGTAATGATCTGTGACTCACTGCATAATATTGTAGTTTTATAGGGTGGCACATCACCCTGTGTAAAACAACTTTAATGACCTGAGGACTG
ATGAGTACAGGAAGTGAGGTTTATCATGAGTAGCATTTATTAAGCATCTGCTAGAATCAAAGCACTGCATTAGCTACTAAGGTACAAAGT
AAGACACAGTTTAATAAGGAAGACAGGGCATCTACCCAAGTCAACAGTTCAGTGACATCTGTTATTTGAACCACACACCAATGCAACCGA
AGTAAATGCTGAAAGGGTGAGAAGAAGGAATAGATTACTATGCATTTTTGAGAGGATGAAGAAGGCTTCTTGGAGAAGGTTTCTGAAAAG
AGATACGGAATTAAGAGAAATAGAAAAGAGCACTGACGAAGCACTCAGGATGGCTATTCAAGGAATTGGGGATCCACAGCAGCTGTGCAC
AACCATCCCTAATGCCAGAAAAATGGGGTAAGGGTGAAGGGAACTGGGTCTAGAGCTTTGCATGTTTTTTTCTGGTTAACCCTTAGAGTC
ACCCTGAAGGTGTGGATCCCATCTTATAATAAGGTGAGGACACTGAGTCAGGAAACTAACTTGCTAAAATCAAGTCCTCCCAGTCCTCCC
ATCAGGTCCTTCCAGATCTGGAGGAGCCAGGATTTGAACTCACATTTGTCTGACTTCAAAATCCATGCTTTTTCTTGTGTTCCAAATTGC
ACAATGGAGTCACTGCCAGTTCAAGCTCCTATGAAAAGGGATGGATGTGAAAAGTCATTTGTTGATTCCACAGATTTTTAGTAGGTACCA
TGTCTCCTGCCTTTATCACTATCCTACTCCTCTGCTACAACTTCTCTGCTACAGGCACCCACTGCAGTTACTTGATATGAGTTAAATGAA
TCCATCCATCCAAACTTCCATTCATTGAATAAATACTTAGCAATGGCTTCCTTTGTATCAGGCACTATTCTAGGAGCTGGGGCTACAGTG
CAGATGGAAACCAGCAAAGCTCACTGCCCTCATGGAGCTTATATGTAAGTGAATAAATCTCAGGGTGGTTCTCCTGTCATAGGTCCTGGC
TCCTCTGCCAGCTCTTCCAAATGGGTTCAGAGAGGTTTTCTCCTTGTCCTGTTGTGTAACTGATAATCCCATGGTGGACCTCACTTTGCT
ATTCATATGCACTAAGTAGTTTATGGTGTGCTTTGTGGCTGGCAATTGTGACAGATTCTATTCTTCTATTGGTATGTGGTTTCTTTGGGG
CATTTGTTTGGATACTGATGGCATCTTCCGGGGGTCTGAGGCACCTACACAAACCTCAGGTCACTATCACGTGATACTGGAGTTGCCTGT
TAAATTATATTTCTTCTTCCACAAAACTGCAGGTTCCCTGAGGGAAAGGTCTATGTCCTGCTCATTTTTGGATCCCTAATGGCTGGCACA
GTACCTGGTGCATAATATGGTTCAACAAATATTTGTAAAATGAATGAATCAAATAGTCCTTCAAAGCATCTTCAGAATCAAGATTGTCAT
CTAGATTGCACCCGAAGTTTATCTTTCTAGTATTCAGAATATAATCAATCATTGCTTAAATTATTCCATTTCATCATTCTTGAATAAAAG
CTACTAATTTTAAATACTAATATCTGAGATATCTTCGAAAAGAAGATTAGTCGTTGTATGTGTTGCTTATAAATTTTCTCTATGGTGGAA
AATATTCCCAAACCATGTCTAAGCAATGAAAAACCAGTGTTCTGGCAGGAAATAAACTGATGTTTGTTGTGTTTTGTATCTGTCTTCCCG
TTCCAAATCATTTATATATACTTGATGGTCTGTGGGCTTGACTTGCAAGTATTTTCCTGGGAGACATTTTTATTCAAAAGACCTGTATTG
CCTGCCAAACCTTCATTTAAGAGACTCATTATGGATGTCATCTGCATCATTGCAAACTTTTCTGGTCGTCTCTATAAATAGCAAGATAAT
ATTTACAGAGTTTTACATTGGCTCTTGAATTTTAAAATATTCTTATAGACAAACATTAATTGGAATGGGGGGTAAGGAGGTAGGAATGGC
TTACTTGCGGAAATGCAGGCTCATTGTTGTGTCTAGTAGGTGCTAGGTGCATTCACACATCTCTTAAGCTTTAAACAACCTATTGAGCCG
GTTTCCATTTCCTTGATCTATTAGATTTAAAAAAATGAAGCATAAAGGAGTTGGCTCTTGCCCTAAGTCATACTACTGATGGAATGAGAA
TACAAACCAAAAACACTTTATTCAAGTCCAGGAAATATCTGCCTTGAAAAAGAATAACTTAAAAATTAAAAGTGTCCTCTATTTGAACAT
GAAAACAGCTAATAAAGATGTGTTATTTTATTTTATTATTATTAATTTTGTCCTCCCATATTGGCAAAGATAAAGCAATTGACAAAAATG
GAATTCTTGTTCAATACTGGCAGGAGTGAAAATTGGTAGAACCTTTCTAGAAGGCAATTTGGCAACATGTATGAAAACCTAAATGTTGAT
ACACCTTTACCCAGCAGTTTGTTTAGGAATTTATCCTAATGAATAAAAGTTGTCCAAGTCTTCAAACATGAGCCCAAAGGTATATTTCAT
GATGTTTATGATATTAAAACATTGGAAACAACTGAAACATCCTTCAGTAAAAGATGGATTAAATAAATTCCATGCAGTTGTCATTTAAAA
ATATTTAGATATATGTTTATTGCTATGGATATATGTTCCCAAAATATTATTGAATCAAAAAGTAGACTACAGGATATATGTTGAATATGA
GCTCATTTATAACATTGAATATTTTAAGATAATGTATGTTTCATAGAGAGATCTTCACCAAATGTTAAGGATTTTTTTTTCTGGGCTGTG
GTATTTGGGTGATCTTTACATTCTTCAGACTCATGTGTGTTTGAAACTTTTTATAATGAACATATATCATTTTTATTAGAAAAGAATAAA

>In-frame_ENST00000542523_ENST00000261233_TCGA-FD-A6TG-01A_TLK2_chr17_60679541_+_IRAK3_chr12_66620503_length(amino acids)=966AA_start in transcript=25_stop in transcript=2925
MMEELHSLDPRRQELLEARFTGVGVSKGPLNSESSNQSLCSVGSLSDKEVETPEKKQNDQRNRKRKAEPYETSQGKGTPRGHKISDYFER
RVEQPLYGLDGSAAKEATEEQSALPTLMSVMLAKPRLDTEQLAQRGAGLCFTFVSAQQNSPSSTGSGNTEHSCSSQKQISIQHRQTQSDL
TIEKISALENSKNSDLEKKEGRIDDLLRANCDLRRQIDEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFTTV
RHGASFTEQWTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKPPAMGQAPPATNEQKQRKSKTNGAENETLTLAEYHEQEEIFKLRLG
HLKKEEAEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKK
ENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLK
PGNILLVNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWFHHPNILELAAYFTETEKFCLIYPYMRNGTLFDRLQCVGDTA
PLPWHIRIGILIGISKAIHYLHNVQPCSVICGSISSANILLDDQFQPKLTDFAMAHFRSHLEHQSCTINMTSSSSKHLWYMPEEYIRQGK
LSIKTDVYSFGIVIMEVLTGCRVVLDDPKHIQLRDLLRELMEKRGLDSCLSFLDKKVPPCPRNFSAKLFCLAGRCAATRAKLRPSMDEVL
NTLESTQASLYFAEDPPTSLKSFRCPSPLFLENVPSIPVEDDESQNNNLLPSDEGLRIDRMTQKTPFECSQSEVMFLSLDKKPESKRNEE

--------------------------------------------------------------
>In-frame_ENST00000582809_ENST00000261233_TCGA-FD-A6TG_TLK2_chr17_60679541_+_IRAK3_chr12_66620502_length(transcript)=9704nt_BP=2115nt
GTTCAGAATACAGCTGAGCCCAGAGATTGCATGGCACCAAGAGAGGTTTCTGTCAAGCCGTCCCGTTCCGAGATGCCCCATCGCACCAAC
GAAGCAACTGCTGAGCAGAAATGATGGAAGAATTGCATAGCCTGGACCCACGACGGCAGGAATTATTGGAGGCCAGGTTTACTGGAGTAG
GTGTTAGTAAGGAAAACTAGAAAAGAGGAGGAAAAAACAATAAATATGCAAGAAGAAATAAATACATTGCAAAACAGAAGAATGGGAAAT
AATCAAGAGTTGGAAAATTAGGAAACAAAAGGCAAAATGAAGGAGAGTACATCGGATATAACAAAAGGGACCACTTAATAGTGAGTCTTC
CAACCAGAGCTTGTGCAGCGTCGGATCCTTGAGTGATAAAGAAGTAGAGACTCCCGAGAAAAAGCAGAATGACCAGCGAAATCGGAAAAG
AAAAGCTGAACCATATGAAACTAGCCAAGGGAAAGGCACTCCTAGGGGACATAAAATTAGTGATTACTTTGAGTTTGCTGGGGGAAGCGC
GCCAGGAACCAGCCCTGGCAGAAGTGTTCCACCAGTTGCACGATCCTCACCGCAACATTCCTTATCCAATCCCTTACCGCGACGAGTAGA
ACAGCCCCTCTATGGTTTAGATGGCAGTGCTGCAAAGGAGGCAACGGAGGAGCAGTCTGCTCTGCCAACCCTCATGTCAGTGATGCTAGC
AAAACCTCGGCTTGACACAGAGCAGCTGGCGCAAAGGGGAGCTGGCCTCTGCTTCACTTTTGTTTCAGCTCAGCAAAACAGTCCCTCATC
TACGGGATCTGGCAACACAGAGCATTCCTGCAGCTCCCAAAAACAGATCTCCATCCAGCACAGACAGACCCAGTCCGACCTCACAATAGA
AAAAATATCTGCACTAGAAAACAGTAAGAATTCTGACTTAGAGAAGAAGGAGGGAAGAATAGATGATTTATTAAGAGCCAACTGTGATTT
GAGACGGCAGATTGATGAACAGCAAAAGATGCTAGAGAAATACAAGGAACGATTAAATAGATGTGTGACAATGAGCAAGAAACTCCTTAT
AGAAAAGTCAAAACAAGAGAAGATGGCGTGTAGAGATAAGAGCATGCAAGACCGCTTGAGACTGGGCCACTTTACTACTGTCCGACACGG
AGCCTCATTTACTGAACAGTGGACAGATGGTTATGCTTTTCAGAATCTTATCAAGCAACAGGAAAGGATAAATTCACAGAGGGAAGAGAT
AGAAAGACAACGGAAAATGTTAGCAAAGCGGAAACCTCCTGCCATGGGTCAGGCCCCTCCTGCAACCAATGAGCAGAAACAGCGGAAAAG
CAAGACCAATGGAGCTGAAAATGAAACGTTAACGTTAGCAGAATACCATGAACAAGAAGAAATCTTCAAACTCAGATTAGGTCATCTTAA
AAAGGAGGAAGCAGAGATCCAGGCAGAGCTGGAGAGACTAGAAAGGGTTAGAAATCTACATATCAGGGAACTAAAAAGGATACATAATGA
AGATAATTCACAATTTAAAGATCATCCAACGCTAAATGACAGATATTTGTTGTTACATCTTTTGGGTAGAGGAGGTTTCAGTGAAGTTTA
CAAGGCATTTGATCTAACAGAGCAAAGATACGTAGCTGTGAAAATTCACCAGTTAAATAAAAACTGGAGAGATGAGAAAAAGGAGAATTA
CCACAAGCATGCATGTAGGGAATACCGGATTCATAAAGAGCTGGATCATCCCAGAATAGTTAAGCTGTATGATTACTTTTCACTGGATAC
TGACTCGTTTTGTACAGTATTAGAATACTGTGAGGGAAATGATCTGGACTTCTACCTGAAACAGCACAAATTAATGTCGGAGAAAGAGGC
CCGGTCCATTATCATGCAGATTGTGAATGCTTTAAAGTACTTAAATGAAATAAAACCTCCCATCATACACTATGACCTCAAACCAGGTAA
TATTCTTTTAGTAAATGGTACAGCGTGTGGAGAGATAAAAATTACAGATTTTGGTCTTTCGAAGATCATGGATGATGATAGCTACAATTC
AGTGGATGGCATGGAGCTAACATCACAAGGTGCTGGTACTTATTGGTTTCATCACCCAAACATACTAGAGTTGGCTGCATATTTTACAGA
GACTGAGAAGTTCTGTCTGATTTATCCATACATGAGAAATGGAACACTTTTTGACAGATTGCAGTGTGTAGGTGACACGGCCCCACTCCC
TTGGCACATTCGAATCGGTATATTAATAGGAATATCCAAAGCCATTCACTACCTGCACAACGTTCAACCATGCTCGGTCATCTGTGGCAG
TATATCAAGTGCAAACATCCTTTTGGATGATCAGTTTCAACCCAAACTAACTGATTTTGCCATGGCACACTTCCGGTCCCACCTAGAACA
TCAGAGTTGTACCATAAATATGACCAGCAGCAGCAGTAAACATCTGTGGTACATGCCAGAAGAGTACATCAGACAGGGGAAACTTTCCAT
TAAAACAGATGTCTACAGCTTTGGAATTGTAATAATGGAAGTTCTAACAGGATGTAGAGTAGTGTTAGATGATCCAAAACATATCCAGCT
GCGGGATCTCCTTAGAGAATTGATGGAGAAGAGAGGCCTGGATTCATGTCTCTCATTTCTAGATAAGAAAGTGCCTCCCTGCCCTCGGAA
TTTCTCTGCCAAGCTCTTCTGTTTGGCAGGCCGGTGTGCTGCAACGCGGGCAAAGTTAAGACCATCAATGGATGAAGTTTTAAATACTCT
TGAAAGTACTCAAGCCAGCTTGTATTTTGCTGAAGATCCTCCCACATCACTAAAGTCCTTCAGGTGTCCTTCTCCTCTATTCCTGGAGAA
TGTACCAAGTATTCCAGTGGAAGATGATGAAAGCCAGAATAACAATTTACTACCTTCTGATGAAGGCCTGAGGATAGACAGAATGACTCA
GAAAACTCCTTTTGAATGCAGCCAGTCTGAGGTTATGTTTCTGAGCTTGGACAAAAAGCCAGAGAGCAAGAGAAATGAGGAAGCTTGCAA
CATGCCCAGTTCTTCTTGTGAAGAAAGTTGGTTCCCAAAGTATATAGTTCCATCCCAGGACTTAAGGCCCTATAAGGTAAATATAGATCC
TTCTTCAGAAGCTCCAGGGCATTCTTGCAGGAGCAGGCCAGTGGAGAGCAGCTGTTCCTCCAAATTTTCCTGGGATGAATATGAACAGTA
CAAAAAAGAATAAATTCTACCAGAAGATAAAGAAAAAAGCAAGTATTGCATAGGCACCTGAGCATAGGTATGACCTTGGGAAGACATTGG
CTCCATAAGCAATGCCAAGAGAATGATCAATAGTGAGTTTGGGTGATGCAGATAAACAATCTGGATAATTCCATTTCTTTTTTCCCAAAC
CCTCAAACAGAGTGCCTTAAAAAATTGTTTTATCAGGATAATTGTCTCATGACCAAATCCACGCTCAATTAGAGCCATTCAAAATTCCTT
AAGATCATGGGTTCTGACTTCAGCCAAACAAAACAATCAAAACCTACCAAAAAGGGACTGGATTGTAATGTCCTCTCCATCATCCTCAGT
GTGAGTCCTCAGAGCCTCCATCTGCCAAGAACATTCAGTTGGATTCCATCGTTTGGTTTAGCTTGCTTGCACGGGTTGTAGGAAATGTCT
AATTTGTAAATGTTAATAGATACCTTTGGAAAGAATCACCTTGTTATTCTGATTGACCCCTCTTGTTTTTTGGTTAATCCCTGACTAGCC
TGCTTGTCTGAAAATGAGCCAGGTTCACCCTTAGCTACGGCATGCTCTGGGTTGAAAGGGGATTTCTTCCCAAGATCTATCCTAAACTCT
TAGGACAGTTTATCCTGTATTGACTATTATTACAGCTTTTTAAAAACAGACTTAGTGACCTATTATATCTTAAGGAGACTATGTGAAATG
TCCATCAAGTAATTTTTATTCCTGAGAAAATGGCTGGTCAAGGGCCTAGGTCAGCTTTTTGTTTAATCTACACCTTTCAACTCTGGGCCT
TCATTCCTGCTGTTTCTTGGATCTCCCTCTTTTGAAATCCTACCAATCATCAGAGCTCTACAAAACAGCCACCTCCTGGAAGCTTCCCTA
ATCTCTACAACCAGAAGTACTCCCTTTATCAGTATTTCCACAGCAATTTCTTTGTATTTCTATTTTATATTTATCACTTTCTGAATTATA
TCAAAGCTGCTTGTCTTATCTCTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCATCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCA
CCGCAAGGTCTGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAAAGGTGGGACTACAGGCGCCCGCCACTACGCCCGG
CTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTAGGCAGGATGGTCTCGATCTCCTGACCTCATGATCCGCCTGCCTGGC
CTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCAGCCTTCATCTCTTTTACTAGGTTGTAAACTCCCTATATTAGTTTTCTA
TTGTTTTTGTAACACATTATCACAAATTTAGTGACTTAAAGTAACATAAATTAATTATTTTGCAGTTCTGGAGGTCAGAATTCCTTAGCA
TTCTTTCTGGAGGCTGTTGGGGAGAACTCACTGCCTTGCCTTTTCCAGCTTCTAGAGGCCACCTGCCTTCTTTGGCTCATGGCCTCTTCC
TCCGTCTTCAAAGCCAGCAACGTGACATTTCAGATCTCCCTCTCTCTGTCTGTCTCACCGCATCTCTTCACTACCCTCTTCCTCTCATTC
TGGCCCTTCTGCATGTCTTTTATAAAGACCTTTGTGATTTCACTGGGCCCACTCATATAAGCCAGGAAAATCTCTGTGTCTCAGATCCTT
AATTTAATTACACCTGCAAAGTCCGTTTTCTCGTGTAAAGTAACATATTCACAGGTTTCTGGAATTGGGACGTGGACATCTTCGGGGGAC
CATTACTCTGTCTGTCATACTCCCTGAGTGTGTAAGGGCCATCTCTTCAGAGCCTAATGTGTCATCCTACACAGAGCAGGTGTTTCCTTA
TAAATTAAGTTGAATTAAATTACCCCTATGAAGCCACATAATCAATAATTCAGCTATAATAAACATTGCCGAATAAATTAACAAAGGGAG
GATAATGACTCCTTATGATGATGGATAGAAACACTGAAGAAAACCATTTTCAGAGGATTTACTGAATTTTCCTCTCCAAGGAGCTTGTAA
TAGAAGGGTAAACCTCTAGTTTCTTGTCCAGCAGAGGAATAGGCTCATGTCTTTTGTTTTATTTTATTTTTTTGGTGAGTCAGTATGGTT
GGGTTAATCATATTCACATTAGATTCCATGTTGAAGAACAACTAATCAAAGAAGAAAATCATCAGGAATCAGGGTGAGATTAACAGACCA
AGGTCAGAAACATGGAGTTACAATTTTCCAAAAAAGCACGAAGTGAGATTAAAACCACAGTAAGTCTTAGTCTGACTGACAGGCTTTATA
CAGGCCCTCGGTAAGCAGTTGGGAGAACCCATGCCCACCACTGCTCTGTACGGTATCTGGCTGCTCAGAGCTCTCTGATTCACAAAAGAG
ATCATCAAGAATTGACTCTGTGTTAAACTGTTTTTCACTTAGAATATGGACCCCCACCAATACATTCAATGAAGGGTCATTAAGGAAGCT
CTGATTAACACCAGGCCCATGCAGTTACTCCGCACATATAATCTGTGGGTATTATGTTGATTTGAACTTGCTTAGCTGACTTAAAGCAGG
GTTTCTCAAACTGTAGTATGCATCAGAATGACTTGGAAAGCTGGTTAAAAACGCAGATTGCTGGGTCCACCCAGCTTCTGATGCAATAGG
TCTGGGGTTAGAAATTTTGCTTTCTAATGAGTTCCCAGGTGATGCTGATGCCAATGATGTGAAGCCCGCTCTTCACATCCGTGAAAATCG
CTGCCTTAAGGTGCTCTTAAATTGTTATAGATTGGTAGATCCTACCTTTCCATCACTGGTATGTTTTTTGAGAAAAGGATCCTTTCTTTT
CATTCTGTTATATTCATCCTATTACATAGGATGTTGGTTAGCACAGAGTGGGAGCTCTAGAAAGATTGTTGACCAATCATCTTATTGACT
AGACCATCTTTCTAGAGTATAACTATTTTGGACACCTCAAAGATGAAGTCAGATAAGCTGGCAGTGACCTGATTAACGTTGTGGTAAGCA
GATGCCACTGTGGCTGGGAAGTACCAAATCTTCTGTTGAGTGATTCAGTCTTCCTGACTAGATTTGCCTTCTAGTGGGTGTATTAATAAG
CGTTAGTTGATATGAATTAAATGTTGCAACTTTCTATGGGTAATAAGAGGATACCTTTATAGTTTCATGATGTGGAGACCAAGATACATA
AGAAAGCAAGAATGAGTCTCCGGGTGTTCCCTCTGATCAGCAAACATGAATTCATAATTTCATTTACTCTCATTTTTGTAATGCACTCTG
AGCAATCCTCCAGGCAGATCCTATTTACTAAGCTTCAGGCTTTTGTCCCATTTTATAATGCCCAAACACATGGAGAAAACATTTTGTTGT
TTTTAAAAACAGGTATGGGATTTCTGATATAATCAATTTTATTGACTTCTTGGGAGTTGTAATGATCTGTGACTCACTGCATAATATTGT
AGTTTTATAGGGTGGCACATCACCCTGTGTAAAACAACTTTAATGACCTGAGGACTGATGAGTACAGGAAGTGAGGTTTATCATGAGTAG
CATTTATTAAGCATCTGCTAGAATCAAAGCACTGCATTAGCTACTAAGGTACAAAGTAAGACACAGTTTAATAAGGAAGACAGGGCATCT
ACCCAAGTCAACAGTTCAGTGACATCTGTTATTTGAACCACACACCAATGCAACCGAAGTAAATGCTGAAAGGGTGAGAAGAAGGAATAG
ATTACTATGCATTTTTGAGAGGATGAAGAAGGCTTCTTGGAGAAGGTTTCTGAAAAGAGATACGGAATTAAGAGAAATAGAAAAGAGCAC
TGACGAAGCACTCAGGATGGCTATTCAAGGAATTGGGGATCCACAGCAGCTGTGCACAACCATCCCTAATGCCAGAAAAATGGGGTAAGG
GTGAAGGGAACTGGGTCTAGAGCTTTGCATGTTTTTTTCTGGTTAACCCTTAGAGTCACCCTGAAGGTGTGGATCCCATCTTATAATAAG
GTGAGGACACTGAGTCAGGAAACTAACTTGCTAAAATCAAGTCCTCCCAGTCCTCCCATCAGGTCCTTCCAGATCTGGAGGAGCCAGGAT
TTGAACTCACATTTGTCTGACTTCAAAATCCATGCTTTTTCTTGTGTTCCAAATTGCACAATGGAGTCACTGCCAGTTCAAGCTCCTATG
AAAAGGGATGGATGTGAAAAGTCATTTGTTGATTCCACAGATTTTTAGTAGGTACCATGTCTCCTGCCTTTATCACTATCCTACTCCTCT
GCTACAACTTCTCTGCTACAGGCACCCACTGCAGTTACTTGATATGAGTTAAATGAATCCATCCATCCAAACTTCCATTCATTGAATAAA
TACTTAGCAATGGCTTCCTTTGTATCAGGCACTATTCTAGGAGCTGGGGCTACAGTGCAGATGGAAACCAGCAAAGCTCACTGCCCTCAT
GGAGCTTATATGTAAGTGAATAAATCTCAGGGTGGTTCTCCTGTCATAGGTCCTGGCTCCTCTGCCAGCTCTTCCAAATGGGTTCAGAGA
GGTTTTCTCCTTGTCCTGTTGTGTAACTGATAATCCCATGGTGGACCTCACTTTGCTATTCATATGCACTAAGTAGTTTATGGTGTGCTT
TGTGGCTGGCAATTGTGACAGATTCTATTCTTCTATTGGTATGTGGTTTCTTTGGGGCATTTGTTTGGATACTGATGGCATCTTCCGGGG
GTCTGAGGCACCTACACAAACCTCAGGTCACTATCACGTGATACTGGAGTTGCCTGTTAAATTATATTTCTTCTTCCACAAAACTGCAGG
TTCCCTGAGGGAAAGGTCTATGTCCTGCTCATTTTTGGATCCCTAATGGCTGGCACAGTACCTGGTGCATAATATGGTTCAACAAATATT
TGTAAAATGAATGAATCAAATAGTCCTTCAAAGCATCTTCAGAATCAAGATTGTCATCTAGATTGCACCCGAAGTTTATCTTTCTAGTAT
TCAGAATATAATCAATCATTGCTTAAATTATTCCATTTCATCATTCTTGAATAAAAGCTACTAATTTTAAATACTAATATCTGAGATATC
TTCGAAAAGAAGATTAGTCGTTGTATGTGTTGCTTATAAATTTTCTCTATGGTGGAAAATATTCCCAAACCATGTCTAAGCAATGAAAAA
CCAGTGTTCTGGCAGGAAATAAACTGATGTTTGTTGTGTTTTGTATCTGTCTTCCCGTTCCAAATCATTTATATATACTTGATGGTCTGT
GGGCTTGACTTGCAAGTATTTTCCTGGGAGACATTTTTATTCAAAAGACCTGTATTGCCTGCCAAACCTTCATTTAAGAGACTCATTATG
GATGTCATCTGCATCATTGCAAACTTTTCTGGTCGTCTCTATAAATAGCAAGATAATATTTACAGAGTTTTACATTGGCTCTTGAATTTT
AAAATATTCTTATAGACAAACATTAATTGGAATGGGGGGTAAGGAGGTAGGAATGGCTTACTTGCGGAAATGCAGGCTCATTGTTGTGTC
TAGTAGGTGCTAGGTGCATTCACACATCTCTTAAGCTTTAAACAACCTATTGAGCCGGTTTCCATTTCCTTGATCTATTAGATTTAAAAA
AATGAAGCATAAAGGAGTTGGCTCTTGCCCTAAGTCATACTACTGATGGAATGAGAATACAAACCAAAAACACTTTATTCAAGTCCAGGA
AATATCTGCCTTGAAAAAGAATAACTTAAAAATTAAAAGTGTCCTCTATTTGAACATGAAAACAGCTAATAAAGATGTGTTATTTTATTT
TATTATTATTAATTTTGTCCTCCCATATTGGCAAAGATAAAGCAATTGACAAAAATGGAATTCTTGTTCAATACTGGCAGGAGTGAAAAT
TGGTAGAACCTTTCTAGAAGGCAATTTGGCAACATGTATGAAAACCTAAATGTTGATACACCTTTACCCAGCAGTTTGTTTAGGAATTTA
TCCTAATGAATAAAAGTTGTCCAAGTCTTCAAACATGAGCCCAAAGGTATATTTCATGATGTTTATGATATTAAAACATTGGAAACAACT
GAAACATCCTTCAGTAAAAGATGGATTAAATAAATTCCATGCAGTTGTCATTTAAAAATATTTAGATATATGTTTATTGCTATGGATATA
TGTTCCCAAAATATTATTGAATCAAAAAGTAGACTACAGGATATATGTTGAATATGAGCTCATTTATAACATTGAATATTTTAAGATAAT
GTATGTTTCATAGAGAGATCTTCACCAAATGTTAAGGATTTTTTTTTCTGGGCTGTGGTATTTGGGTGATCTTTACATTCTTCAGACTCA

>In-frame_ENST00000582809_ENST00000261233_TCGA-FD-A6TG_TLK2_chr17_60679541_+_IRAK3_chr12_66620502_length(amino acids)=960AA_start in transcript=370_stop in transcript=3252
MCSVGSLSDKEVETPEKKQNDQRNRKRKAEPYETSQGKGTPRGHKISDYFEFAGGSAPGTSPGRSVPPVARSSPQHSLSNPLPRRVEQPL
YGLDGSAAKEATEEQSALPTLMSVMLAKPRLDTEQLAQRGAGLCFTFVSAQQNSPSSTGSGNTEHSCSSQKQISIQHRQTQSDLTIEKIS
ALENSKNSDLEKKEGRIDDLLRANCDLRRQIDEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFTTVRHGASF
TEQWTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKPPAMGQAPPATNEQKQRKSKTNGAENETLTLAEYHEQEEIFKLRLGHLKKEE
AEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKH
ACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILL
VNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWFHHPNILELAAYFTETEKFCLIYPYMRNGTLFDRLQCVGDTAPLPWHI
RIGILIGISKAIHYLHNVQPCSVICGSISSANILLDDQFQPKLTDFAMAHFRSHLEHQSCTINMTSSSSKHLWYMPEEYIRQGKLSIKTD
VYSFGIVIMEVLTGCRVVLDDPKHIQLRDLLRELMEKRGLDSCLSFLDKKVPPCPRNFSAKLFCLAGRCAATRAKLRPSMDEVLNTLEST
QASLYFAEDPPTSLKSFRCPSPLFLENVPSIPVEDDESQNNNLLPSDEGLRIDRMTQKTPFECSQSEVMFLSLDKKPESKRNEEACNMPS

--------------------------------------------------------------
>In-frame_ENST00000326270_ENST00000261233_TCGA-FD-A6TG_TLK2_chr17_60679541_+_IRAK3_chr12_66620502_length(transcript)=9782nt_BP=2193nt
GCGGCCGCCCGGGCCCGGGCCCGCGTCGGGCGCCTGGCTCTGTACGCGAGCCCGGGGATCTGCGGCCTTCGTGCCCCCCCTCCCCCGCCC
GCCCTCTCGTGGAGCCCGGCGCCGGCGGCGGCTGCCCGGGCGGGGGGTTGCGGCGCTCAGGAGAGGCCCCGGCTCCGCCCCGGGCCTGCC
CAGGGGGAGAGCGGAGCGGTCCGCAGCCGGGTCGGGTCGGGGCCCCTCCCGGGAGGAGCGTGGAGCGGCGGCGGCGGCGGCGGCAGAAAT
GATGGAAGAATTGCATAGCCTGGACCCACGACGGCAGGAATTATTGGAGGCCAGGTTTACTGGAGTAGGTGTTAGTAAGGGACCACTTAA
TAGTGAGTCTTCCAACCAGAGCTTGTGCAGCGTCGGATCCTTGAGTGATAAAGAAGTAGAGACTCCCGAGAAAAAGCAGAATGACCAGCG
AAATCGGAAAAGAAAAGCTGAACCATATGAAACTAGCCAAGGGAAAGGCACTCCTAGGGGACATAAAATTAGTGATTACTTTGAGTTTGC
TGGGGGAAGCGCGCCAGGAACCAGCCCTGGCAGAAGTGTTCCACCAGTTGCACGATCCTCACCGCAACATTCCTTATCCAATCCCTTACC
GCGACGAGTAGAACAGCCCCTCTATGGTTTAGATGGCAGTGCTGCAAAGGAGGCAACGGAGGAGCAGTCTGCTCTGCCAACCCTCATGTC
AGTGATGCTAGCAAAACCTCGGCTTGACACAGAGCAGCTGGCGCAAAGGGGAGCTGGCCTCTGCTTCACTTTTGTTTCAGCTCAGCAAAA
CAGTCCCTCATCTACGGGATCTGGCAACACAGAGCATTCCTGCAGCTCCCAAAAACAGATCTCCATCCAGCACAGACAGACCCAGTCCGA
CCTCACAATAGAAAAAATATCTGCACTAGAAAACAGTAAGAATTCTGACTTAGAGAAGAAGGAGGGAAGAATAGATGATTTATTAAGAGC
CAACTGTGATTTGAGACGGCAGATTGATGAACAGCAAAAGATGCTAGAGAAATACAAGGAACGATTAAATAGATGTGTGACAATGAGCAA
GAAACTCCTTATAGAAAAGTCAAAACAAGAGAAGATGGCGTGTAGAGATAAGAGCATGCAAGACCGCTTGAGACTGGGCCACTTTACTAC
TGTCCGACACGGAGCCTCATTTACTGAACAGTGGACAGATGGTTATGCTTTTCAGAATCTTATCAAGCAACAGGAAAGGATAAATTCACA
GAGGGAAGAGATAGAAAGACAACGGAAAATGTTAGCAAAGCGGAAACCTCCTGCCATGGGTCAGGCCCCTCCTGCAACCAATGAGCAGAA
ACAGCGGAAAAGCAAGACCAATGGAGCTGAAAATGAAACGCCCTCTTCTGGGAATACAGAGCTAAAGGATACAGCCCCAGCCTTAGGAGC
CCACAGTTTACTTAGGTTAACGTTAGCAGAATACCATGAACAAGAAGAAATCTTCAAACTCAGATTAGGTCATCTTAAAAAGGAGGAAGC
AGAGATCCAGGCAGAGCTGGAGAGACTAGAAAGGGTTAGAAATCTACATATCAGGGAACTAAAAAGGATACATAATGAAGATAATTCACA
ATTTAAAGATCATCCAACGCTAAATGACAGATATTTGTTGTTACATCTTTTGGGTAGAGGAGGTTTCAGTGAAGTTTACAAGGCATTTGA
TCTAACAGAGCAAAGATACGTAGCTGTGAAAATTCACCAGTTAAATAAAAACTGGAGAGATGAGAAAAAGGAGAATTACCACAAGCATGC
ATGTAGGGAATACCGGATTCATAAAGAGCTGGATCATCCCAGAATAGTTAAGCTGTATGATTACTTTTCACTGGATACTGACTCGTTTTG
TACAGTATTAGAATACTGTGAGGGAAATGATCTGGACTTCTACCTGAAACAGCACAAATTAATGTCGGAGAAAGAGGCCCGGTCCATTAT
CATGCAGATTGTGAATGCTTTAAAGTACTTAAATGAAATAAAACCTCCCATCATACACTATGACCTCAAACCAGGTAATATTCTTTTAGT
AAATGGTACAGCGTGTGGAGAGATAAAAATTACAGATTTTGGTCTTTCGAAGATCATGGATGATGATAGCTACAATTCAGTGGATGGCAT
GGAGCTAACATCACAAGGTGCTGGTACTTATTGGTTTCATCACCCAAACATACTAGAGTTGGCTGCATATTTTACAGAGACTGAGAAGTT
CTGTCTGATTTATCCATACATGAGAAATGGAACACTTTTTGACAGATTGCAGTGTGTAGGTGACACGGCCCCACTCCCTTGGCACATTCG
AATCGGTATATTAATAGGAATATCCAAAGCCATTCACTACCTGCACAACGTTCAACCATGCTCGGTCATCTGTGGCAGTATATCAAGTGC
AAACATCCTTTTGGATGATCAGTTTCAACCCAAACTAACTGATTTTGCCATGGCACACTTCCGGTCCCACCTAGAACATCAGAGTTGTAC
CATAAATATGACCAGCAGCAGCAGTAAACATCTGTGGTACATGCCAGAAGAGTACATCAGACAGGGGAAACTTTCCATTAAAACAGATGT
CTACAGCTTTGGAATTGTAATAATGGAAGTTCTAACAGGATGTAGAGTAGTGTTAGATGATCCAAAACATATCCAGCTGCGGGATCTCCT
TAGAGAATTGATGGAGAAGAGAGGCCTGGATTCATGTCTCTCATTTCTAGATAAGAAAGTGCCTCCCTGCCCTCGGAATTTCTCTGCCAA
GCTCTTCTGTTTGGCAGGCCGGTGTGCTGCAACGCGGGCAAAGTTAAGACCATCAATGGATGAAGTTTTAAATACTCTTGAAAGTACTCA
AGCCAGCTTGTATTTTGCTGAAGATCCTCCCACATCACTAAAGTCCTTCAGGTGTCCTTCTCCTCTATTCCTGGAGAATGTACCAAGTAT
TCCAGTGGAAGATGATGAAAGCCAGAATAACAATTTACTACCTTCTGATGAAGGCCTGAGGATAGACAGAATGACTCAGAAAACTCCTTT
TGAATGCAGCCAGTCTGAGGTTATGTTTCTGAGCTTGGACAAAAAGCCAGAGAGCAAGAGAAATGAGGAAGCTTGCAACATGCCCAGTTC
TTCTTGTGAAGAAAGTTGGTTCCCAAAGTATATAGTTCCATCCCAGGACTTAAGGCCCTATAAGGTAAATATAGATCCTTCTTCAGAAGC
TCCAGGGCATTCTTGCAGGAGCAGGCCAGTGGAGAGCAGCTGTTCCTCCAAATTTTCCTGGGATGAATATGAACAGTACAAAAAAGAATA
AATTCTACCAGAAGATAAAGAAAAAAGCAAGTATTGCATAGGCACCTGAGCATAGGTATGACCTTGGGAAGACATTGGCTCCATAAGCAA
TGCCAAGAGAATGATCAATAGTGAGTTTGGGTGATGCAGATAAACAATCTGGATAATTCCATTTCTTTTTTCCCAAACCCTCAAACAGAG
TGCCTTAAAAAATTGTTTTATCAGGATAATTGTCTCATGACCAAATCCACGCTCAATTAGAGCCATTCAAAATTCCTTAAGATCATGGGT
TCTGACTTCAGCCAAACAAAACAATCAAAACCTACCAAAAAGGGACTGGATTGTAATGTCCTCTCCATCATCCTCAGTGTGAGTCCTCAG
AGCCTCCATCTGCCAAGAACATTCAGTTGGATTCCATCGTTTGGTTTAGCTTGCTTGCACGGGTTGTAGGAAATGTCTAATTTGTAAATG
TTAATAGATACCTTTGGAAAGAATCACCTTGTTATTCTGATTGACCCCTCTTGTTTTTTGGTTAATCCCTGACTAGCCTGCTTGTCTGAA
AATGAGCCAGGTTCACCCTTAGCTACGGCATGCTCTGGGTTGAAAGGGGATTTCTTCCCAAGATCTATCCTAAACTCTTAGGACAGTTTA
TCCTGTATTGACTATTATTACAGCTTTTTAAAAACAGACTTAGTGACCTATTATATCTTAAGGAGACTATGTGAAATGTCCATCAAGTAA
TTTTTATTCCTGAGAAAATGGCTGGTCAAGGGCCTAGGTCAGCTTTTTGTTTAATCTACACCTTTCAACTCTGGGCCTTCATTCCTGCTG
TTTCTTGGATCTCCCTCTTTTGAAATCCTACCAATCATCAGAGCTCTACAAAACAGCCACCTCCTGGAAGCTTCCCTAATCTCTACAACC
AGAAGTACTCCCTTTATCAGTATTTCCACAGCAATTTCTTTGTATTTCTATTTTATATTTATCACTTTCTGAATTATATCAAAGCTGCTT
GTCTTATCTCTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCATCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACCGCAAGGTCTG
CCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAAAGGTGGGACTACAGGCGCCCGCCACTACGCCCGGCTAATTTTTTGT
ATTTTTAGTAGAGACGGGGTTTCACCATGTTAGGCAGGATGGTCTCGATCTCCTGACCTCATGATCCGCCTGCCTGGCCTCCCAAAGTGC
TGGGATTACAGGCGTGAGCCACCGCGCCCAGCCTTCATCTCTTTTACTAGGTTGTAAACTCCCTATATTAGTTTTCTATTGTTTTTGTAA
CACATTATCACAAATTTAGTGACTTAAAGTAACATAAATTAATTATTTTGCAGTTCTGGAGGTCAGAATTCCTTAGCATTCTTTCTGGAG
GCTGTTGGGGAGAACTCACTGCCTTGCCTTTTCCAGCTTCTAGAGGCCACCTGCCTTCTTTGGCTCATGGCCTCTTCCTCCGTCTTCAAA
GCCAGCAACGTGACATTTCAGATCTCCCTCTCTCTGTCTGTCTCACCGCATCTCTTCACTACCCTCTTCCTCTCATTCTGGCCCTTCTGC
ATGTCTTTTATAAAGACCTTTGTGATTTCACTGGGCCCACTCATATAAGCCAGGAAAATCTCTGTGTCTCAGATCCTTAATTTAATTACA
CCTGCAAAGTCCGTTTTCTCGTGTAAAGTAACATATTCACAGGTTTCTGGAATTGGGACGTGGACATCTTCGGGGGACCATTACTCTGTC
TGTCATACTCCCTGAGTGTGTAAGGGCCATCTCTTCAGAGCCTAATGTGTCATCCTACACAGAGCAGGTGTTTCCTTATAAATTAAGTTG
AATTAAATTACCCCTATGAAGCCACATAATCAATAATTCAGCTATAATAAACATTGCCGAATAAATTAACAAAGGGAGGATAATGACTCC
TTATGATGATGGATAGAAACACTGAAGAAAACCATTTTCAGAGGATTTACTGAATTTTCCTCTCCAAGGAGCTTGTAATAGAAGGGTAAA
CCTCTAGTTTCTTGTCCAGCAGAGGAATAGGCTCATGTCTTTTGTTTTATTTTATTTTTTTGGTGAGTCAGTATGGTTGGGTTAATCATA
TTCACATTAGATTCCATGTTGAAGAACAACTAATCAAAGAAGAAAATCATCAGGAATCAGGGTGAGATTAACAGACCAAGGTCAGAAACA
TGGAGTTACAATTTTCCAAAAAAGCACGAAGTGAGATTAAAACCACAGTAAGTCTTAGTCTGACTGACAGGCTTTATACAGGCCCTCGGT
AAGCAGTTGGGAGAACCCATGCCCACCACTGCTCTGTACGGTATCTGGCTGCTCAGAGCTCTCTGATTCACAAAAGAGATCATCAAGAAT
TGACTCTGTGTTAAACTGTTTTTCACTTAGAATATGGACCCCCACCAATACATTCAATGAAGGGTCATTAAGGAAGCTCTGATTAACACC
AGGCCCATGCAGTTACTCCGCACATATAATCTGTGGGTATTATGTTGATTTGAACTTGCTTAGCTGACTTAAAGCAGGGTTTCTCAAACT
GTAGTATGCATCAGAATGACTTGGAAAGCTGGTTAAAAACGCAGATTGCTGGGTCCACCCAGCTTCTGATGCAATAGGTCTGGGGTTAGA
AATTTTGCTTTCTAATGAGTTCCCAGGTGATGCTGATGCCAATGATGTGAAGCCCGCTCTTCACATCCGTGAAAATCGCTGCCTTAAGGT
GCTCTTAAATTGTTATAGATTGGTAGATCCTACCTTTCCATCACTGGTATGTTTTTTGAGAAAAGGATCCTTTCTTTTCATTCTGTTATA
TTCATCCTATTACATAGGATGTTGGTTAGCACAGAGTGGGAGCTCTAGAAAGATTGTTGACCAATCATCTTATTGACTAGACCATCTTTC
TAGAGTATAACTATTTTGGACACCTCAAAGATGAAGTCAGATAAGCTGGCAGTGACCTGATTAACGTTGTGGTAAGCAGATGCCACTGTG
GCTGGGAAGTACCAAATCTTCTGTTGAGTGATTCAGTCTTCCTGACTAGATTTGCCTTCTAGTGGGTGTATTAATAAGCGTTAGTTGATA
TGAATTAAATGTTGCAACTTTCTATGGGTAATAAGAGGATACCTTTATAGTTTCATGATGTGGAGACCAAGATACATAAGAAAGCAAGAA
TGAGTCTCCGGGTGTTCCCTCTGATCAGCAAACATGAATTCATAATTTCATTTACTCTCATTTTTGTAATGCACTCTGAGCAATCCTCCA
GGCAGATCCTATTTACTAAGCTTCAGGCTTTTGTCCCATTTTATAATGCCCAAACACATGGAGAAAACATTTTGTTGTTTTTAAAAACAG
GTATGGGATTTCTGATATAATCAATTTTATTGACTTCTTGGGAGTTGTAATGATCTGTGACTCACTGCATAATATTGTAGTTTTATAGGG
TGGCACATCACCCTGTGTAAAACAACTTTAATGACCTGAGGACTGATGAGTACAGGAAGTGAGGTTTATCATGAGTAGCATTTATTAAGC
ATCTGCTAGAATCAAAGCACTGCATTAGCTACTAAGGTACAAAGTAAGACACAGTTTAATAAGGAAGACAGGGCATCTACCCAAGTCAAC
AGTTCAGTGACATCTGTTATTTGAACCACACACCAATGCAACCGAAGTAAATGCTGAAAGGGTGAGAAGAAGGAATAGATTACTATGCAT
TTTTGAGAGGATGAAGAAGGCTTCTTGGAGAAGGTTTCTGAAAAGAGATACGGAATTAAGAGAAATAGAAAAGAGCACTGACGAAGCACT
CAGGATGGCTATTCAAGGAATTGGGGATCCACAGCAGCTGTGCACAACCATCCCTAATGCCAGAAAAATGGGGTAAGGGTGAAGGGAACT
GGGTCTAGAGCTTTGCATGTTTTTTTCTGGTTAACCCTTAGAGTCACCCTGAAGGTGTGGATCCCATCTTATAATAAGGTGAGGACACTG
AGTCAGGAAACTAACTTGCTAAAATCAAGTCCTCCCAGTCCTCCCATCAGGTCCTTCCAGATCTGGAGGAGCCAGGATTTGAACTCACAT
TTGTCTGACTTCAAAATCCATGCTTTTTCTTGTGTTCCAAATTGCACAATGGAGTCACTGCCAGTTCAAGCTCCTATGAAAAGGGATGGA
TGTGAAAAGTCATTTGTTGATTCCACAGATTTTTAGTAGGTACCATGTCTCCTGCCTTTATCACTATCCTACTCCTCTGCTACAACTTCT
CTGCTACAGGCACCCACTGCAGTTACTTGATATGAGTTAAATGAATCCATCCATCCAAACTTCCATTCATTGAATAAATACTTAGCAATG
GCTTCCTTTGTATCAGGCACTATTCTAGGAGCTGGGGCTACAGTGCAGATGGAAACCAGCAAAGCTCACTGCCCTCATGGAGCTTATATG
TAAGTGAATAAATCTCAGGGTGGTTCTCCTGTCATAGGTCCTGGCTCCTCTGCCAGCTCTTCCAAATGGGTTCAGAGAGGTTTTCTCCTT
GTCCTGTTGTGTAACTGATAATCCCATGGTGGACCTCACTTTGCTATTCATATGCACTAAGTAGTTTATGGTGTGCTTTGTGGCTGGCAA
TTGTGACAGATTCTATTCTTCTATTGGTATGTGGTTTCTTTGGGGCATTTGTTTGGATACTGATGGCATCTTCCGGGGGTCTGAGGCACC
TACACAAACCTCAGGTCACTATCACGTGATACTGGAGTTGCCTGTTAAATTATATTTCTTCTTCCACAAAACTGCAGGTTCCCTGAGGGA
AAGGTCTATGTCCTGCTCATTTTTGGATCCCTAATGGCTGGCACAGTACCTGGTGCATAATATGGTTCAACAAATATTTGTAAAATGAAT
GAATCAAATAGTCCTTCAAAGCATCTTCAGAATCAAGATTGTCATCTAGATTGCACCCGAAGTTTATCTTTCTAGTATTCAGAATATAAT
CAATCATTGCTTAAATTATTCCATTTCATCATTCTTGAATAAAAGCTACTAATTTTAAATACTAATATCTGAGATATCTTCGAAAAGAAG
ATTAGTCGTTGTATGTGTTGCTTATAAATTTTCTCTATGGTGGAAAATATTCCCAAACCATGTCTAAGCAATGAAAAACCAGTGTTCTGG
CAGGAAATAAACTGATGTTTGTTGTGTTTTGTATCTGTCTTCCCGTTCCAAATCATTTATATATACTTGATGGTCTGTGGGCTTGACTTG
CAAGTATTTTCCTGGGAGACATTTTTATTCAAAAGACCTGTATTGCCTGCCAAACCTTCATTTAAGAGACTCATTATGGATGTCATCTGC
ATCATTGCAAACTTTTCTGGTCGTCTCTATAAATAGCAAGATAATATTTACAGAGTTTTACATTGGCTCTTGAATTTTAAAATATTCTTA
TAGACAAACATTAATTGGAATGGGGGGTAAGGAGGTAGGAATGGCTTACTTGCGGAAATGCAGGCTCATTGTTGTGTCTAGTAGGTGCTA
GGTGCATTCACACATCTCTTAAGCTTTAAACAACCTATTGAGCCGGTTTCCATTTCCTTGATCTATTAGATTTAAAAAAATGAAGCATAA
AGGAGTTGGCTCTTGCCCTAAGTCATACTACTGATGGAATGAGAATACAAACCAAAAACACTTTATTCAAGTCCAGGAAATATCTGCCTT
GAAAAAGAATAACTTAAAAATTAAAAGTGTCCTCTATTTGAACATGAAAACAGCTAATAAAGATGTGTTATTTTATTTTATTATTATTAA
TTTTGTCCTCCCATATTGGCAAAGATAAAGCAATTGACAAAAATGGAATTCTTGTTCAATACTGGCAGGAGTGAAAATTGGTAGAACCTT
TCTAGAAGGCAATTTGGCAACATGTATGAAAACCTAAATGTTGATACACCTTTACCCAGCAGTTTGTTTAGGAATTTATCCTAATGAATA
AAAGTTGTCCAAGTCTTCAAACATGAGCCCAAAGGTATATTTCATGATGTTTATGATATTAAAACATTGGAAACAACTGAAACATCCTTC
AGTAAAAGATGGATTAAATAAATTCCATGCAGTTGTCATTTAAAAATATTTAGATATATGTTTATTGCTATGGATATATGTTCCCAAAAT
ATTATTGAATCAAAAAGTAGACTACAGGATATATGTTGAATATGAGCTCATTTATAACATTGAATATTTTAAGATAATGTATGTTTCATA
GAGAGATCTTCACCAAATGTTAAGGATTTTTTTTTCTGGGCTGTGGTATTTGGGTGATCTTTACATTCTTCAGACTCATGTGTGTTTGAA

>In-frame_ENST00000326270_ENST00000261233_TCGA-FD-A6TG_TLK2_chr17_60679541_+_IRAK3_chr12_66620502_length(amino acids)=1069AA_start in transcript=121_stop in transcript=3330
MPGRGVAALRRGPGSAPGLPRGRAERSAAGSGRGPSREERGAAAAAAAEMMEELHSLDPRRQELLEARFTGVGVSKGPLNSESSNQSLCS
VGSLSDKEVETPEKKQNDQRNRKRKAEPYETSQGKGTPRGHKISDYFEFAGGSAPGTSPGRSVPPVARSSPQHSLSNPLPRRVEQPLYGL
DGSAAKEATEEQSALPTLMSVMLAKPRLDTEQLAQRGAGLCFTFVSAQQNSPSSTGSGNTEHSCSSQKQISIQHRQTQSDLTIEKISALE
NSKNSDLEKKEGRIDDLLRANCDLRRQIDEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFTTVRHGASFTEQ
WTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKPPAMGQAPPATNEQKQRKSKTNGAENETPSSGNTELKDTAPALGAHSLLRLTLAE
YHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVK
IHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYL
NEIKPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWFHHPNILELAAYFTETEKFCLIYPYMRNG
TLFDRLQCVGDTAPLPWHIRIGILIGISKAIHYLHNVQPCSVICGSISSANILLDDQFQPKLTDFAMAHFRSHLEHQSCTINMTSSSSKH
LWYMPEEYIRQGKLSIKTDVYSFGIVIMEVLTGCRVVLDDPKHIQLRDLLRELMEKRGLDSCLSFLDKKVPPCPRNFSAKLFCLAGRCAA
TRAKLRPSMDEVLNTLESTQASLYFAEDPPTSLKSFRCPSPLFLENVPSIPVEDDESQNNNLLPSDEGLRIDRMTQKTPFECSQSEVMFL

--------------------------------------------------------------
>In-frame_ENST00000346027_ENST00000261233_TCGA-FD-A6TG_TLK2_chr17_60679541_+_IRAK3_chr12_66620502_length(transcript)=9719nt_BP=2130nt
GCGGCCGCCCGGGCCCGGGCCCGCGTCGGGCGCCTGGCTCTGTACGCGAGCCCGGGGATCTGCGGCCTTCGTGCCCCCCCTCCCCCGCCC
GCCCTCTCGTGGAGCCCGGCGCCGGCGGCGGCTGCCCGGGCGGGGGGTTGCGGCGCTCAGGAGAGGCCCCGGCTCCGCCCCGGGCCTGCC
CAGGGGGAGAGCGGAGCGGTCCGCAGCCGGGTCGGGTCGGGGCCCCTCCCGGGAGGAGCGTGGAGCGGCGGCGGCGGCGGCGGCAGCAGA
AATGATGGAAGAATTGCATAGCCTGGACCCACGACGGCAGGAATTATTGGAGGCCAGGTTTACTGGAGTAGGTGTTAGTAAGGGACCACT
TAATAGTGAGTCTTCCAACCAGAGCTTGTGCAGCGTCGGATCCTTGAGTGATAAAGAAGTAGAGACTCCCGAGAAAAAGCAGAATGACCA
GCGAAATCGGAAAAGAAAAGCTGAACCATATGAAACTAGCCAAGGGAAAGGCACTCCTAGGGGACATAAAATTAGTGATTACTTTGAGTT
TGCTGGGGGAAGCGCGCCAGGAACCAGCCCTGGCAGAAGTGTTCCACCAGTTGCACGATCCTCACCGCAACATTCCTTATCCAATCCCTT
ACCGCGACGAGTAGAACAGCCCCTCTATGGTTTAGATGGCAGTGCTGCAAAGGAGGCAACGGAGGAGCAGTCTGCTCTGCCAACCCTCAT
GTCAGTGATGCTAGCAAAACCTCGGCTTGACACAGAGCAGCTGGCGCAAAGGGGAGCTGGCCTCTGCTTCACTTTTGTTTCAGCTCAGCA
AAACAGTCCCTCATCTACGGGATCTGGCAACACAGAGCATTCCTGCAGCTCCCAAAAACAGATCTCCATCCAGCACAGACAGACCCAGTC
CGACCTCACAATAGAAAAAATATCTGCACTAGAAAACAGTAAGAATTCTGACTTAGAGAAGAAGGAGGGAAGAATAGATGATTTATTAAG
AGCCAACTGTGATTTGAGACGGCAGATTGATGAACAGCAAAAGATGCTAGAGAAATACAAGGAACGATTAAATAGATGTGTGACAATGAG
CAAGAAACTCCTTATAGAAAAGTCAAAACAAGAGAAGATGGCGTGTAGAGATAAGAGCATGCAAGACCGCTTGAGACTGGGCCACTTTAC
TACTGTCCGACACGGAGCCTCATTTACTGAACAGTGGACAGATGGTTATGCTTTTCAGAATCTTATCAAGCAACAGGAAAGGATAAATTC
ACAGAGGGAAGAGATAGAAAGACAACGGAAAATGTTAGCAAAGCGGAAACCTCCTGCCATGGGTCAGGCCCCTCCTGCAACCAATGAGCA
GAAACAGCGGAAAAGCAAGACCAATGGAGCTGAAAATGAAACGTTAACGTTAGCAGAATACCATGAACAAGAAGAAATCTTCAAACTCAG
ATTAGGTCATCTTAAAAAGGAGGAAGCAGAGATCCAGGCAGAGCTGGAGAGACTAGAAAGGGTTAGAAATCTACATATCAGGGAACTAAA
AAGGATACATAATGAAGATAATTCACAATTTAAAGATCATCCAACGCTAAATGACAGATATTTGTTGTTACATCTTTTGGGTAGAGGAGG
TTTCAGTGAAGTTTACAAGGCATTTGATCTAACAGAGCAAAGATACGTAGCTGTGAAAATTCACCAGTTAAATAAAAACTGGAGAGATGA
GAAAAAGGAGAATTACCACAAGCATGCATGTAGGGAATACCGGATTCATAAAGAGCTGGATCATCCCAGAATAGTTAAGCTGTATGATTA
CTTTTCACTGGATACTGACTCGTTTTGTACAGTATTAGAATACTGTGAGGGAAATGATCTGGACTTCTACCTGAAACAGCACAAATTAAT
GTCGGAGAAAGAGGCCCGGTCCATTATCATGCAGATTGTGAATGCTTTAAAGTACTTAAATGAAATAAAACCTCCCATCATACACTATGA
CCTCAAACCAGGTAATATTCTTTTAGTAAATGGTACAGCGTGTGGAGAGATAAAAATTACAGATTTTGGTCTTTCGAAGATCATGGATGA
TGATAGCTACAATTCAGTGGATGGCATGGAGCTAACATCACAAGGTGCTGGTACTTATTGGTTTCATCACCCAAACATACTAGAGTTGGC
TGCATATTTTACAGAGACTGAGAAGTTCTGTCTGATTTATCCATACATGAGAAATGGAACACTTTTTGACAGATTGCAGTGTGTAGGTGA
CACGGCCCCACTCCCTTGGCACATTCGAATCGGTATATTAATAGGAATATCCAAAGCCATTCACTACCTGCACAACGTTCAACCATGCTC
GGTCATCTGTGGCAGTATATCAAGTGCAAACATCCTTTTGGATGATCAGTTTCAACCCAAACTAACTGATTTTGCCATGGCACACTTCCG
GTCCCACCTAGAACATCAGAGTTGTACCATAAATATGACCAGCAGCAGCAGTAAACATCTGTGGTACATGCCAGAAGAGTACATCAGACA
GGGGAAACTTTCCATTAAAACAGATGTCTACAGCTTTGGAATTGTAATAATGGAAGTTCTAACAGGATGTAGAGTAGTGTTAGATGATCC
AAAACATATCCAGCTGCGGGATCTCCTTAGAGAATTGATGGAGAAGAGAGGCCTGGATTCATGTCTCTCATTTCTAGATAAGAAAGTGCC
TCCCTGCCCTCGGAATTTCTCTGCCAAGCTCTTCTGTTTGGCAGGCCGGTGTGCTGCAACGCGGGCAAAGTTAAGACCATCAATGGATGA
AGTTTTAAATACTCTTGAAAGTACTCAAGCCAGCTTGTATTTTGCTGAAGATCCTCCCACATCACTAAAGTCCTTCAGGTGTCCTTCTCC
TCTATTCCTGGAGAATGTACCAAGTATTCCAGTGGAAGATGATGAAAGCCAGAATAACAATTTACTACCTTCTGATGAAGGCCTGAGGAT
AGACAGAATGACTCAGAAAACTCCTTTTGAATGCAGCCAGTCTGAGGTTATGTTTCTGAGCTTGGACAAAAAGCCAGAGAGCAAGAGAAA
TGAGGAAGCTTGCAACATGCCCAGTTCTTCTTGTGAAGAAAGTTGGTTCCCAAAGTATATAGTTCCATCCCAGGACTTAAGGCCCTATAA
GGTAAATATAGATCCTTCTTCAGAAGCTCCAGGGCATTCTTGCAGGAGCAGGCCAGTGGAGAGCAGCTGTTCCTCCAAATTTTCCTGGGA
TGAATATGAACAGTACAAAAAAGAATAAATTCTACCAGAAGATAAAGAAAAAAGCAAGTATTGCATAGGCACCTGAGCATAGGTATGACC
TTGGGAAGACATTGGCTCCATAAGCAATGCCAAGAGAATGATCAATAGTGAGTTTGGGTGATGCAGATAAACAATCTGGATAATTCCATT
TCTTTTTTCCCAAACCCTCAAACAGAGTGCCTTAAAAAATTGTTTTATCAGGATAATTGTCTCATGACCAAATCCACGCTCAATTAGAGC
CATTCAAAATTCCTTAAGATCATGGGTTCTGACTTCAGCCAAACAAAACAATCAAAACCTACCAAAAAGGGACTGGATTGTAATGTCCTC
TCCATCATCCTCAGTGTGAGTCCTCAGAGCCTCCATCTGCCAAGAACATTCAGTTGGATTCCATCGTTTGGTTTAGCTTGCTTGCACGGG
TTGTAGGAAATGTCTAATTTGTAAATGTTAATAGATACCTTTGGAAAGAATCACCTTGTTATTCTGATTGACCCCTCTTGTTTTTTGGTT
AATCCCTGACTAGCCTGCTTGTCTGAAAATGAGCCAGGTTCACCCTTAGCTACGGCATGCTCTGGGTTGAAAGGGGATTTCTTCCCAAGA
TCTATCCTAAACTCTTAGGACAGTTTATCCTGTATTGACTATTATTACAGCTTTTTAAAAACAGACTTAGTGACCTATTATATCTTAAGG
AGACTATGTGAAATGTCCATCAAGTAATTTTTATTCCTGAGAAAATGGCTGGTCAAGGGCCTAGGTCAGCTTTTTGTTTAATCTACACCT
TTCAACTCTGGGCCTTCATTCCTGCTGTTTCTTGGATCTCCCTCTTTTGAAATCCTACCAATCATCAGAGCTCTACAAAACAGCCACCTC
CTGGAAGCTTCCCTAATCTCTACAACCAGAAGTACTCCCTTTATCAGTATTTCCACAGCAATTTCTTTGTATTTCTATTTTATATTTATC
ACTTTCTGAATTATATCAAAGCTGCTTGTCTTATCTCTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCATCCAGGCTGGAGTGCAGTGG
CACAATCTCGGCTCACCGCAAGGTCTGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAAAGGTGGGACTACAGGCGCC
CGCCACTACGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTAGGCAGGATGGTCTCGATCTCCTGACCTCATG
ATCCGCCTGCCTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCAGCCTTCATCTCTTTTACTAGGTTGTAAACTCCC
TATATTAGTTTTCTATTGTTTTTGTAACACATTATCACAAATTTAGTGACTTAAAGTAACATAAATTAATTATTTTGCAGTTCTGGAGGT
CAGAATTCCTTAGCATTCTTTCTGGAGGCTGTTGGGGAGAACTCACTGCCTTGCCTTTTCCAGCTTCTAGAGGCCACCTGCCTTCTTTGG
CTCATGGCCTCTTCCTCCGTCTTCAAAGCCAGCAACGTGACATTTCAGATCTCCCTCTCTCTGTCTGTCTCACCGCATCTCTTCACTACC
CTCTTCCTCTCATTCTGGCCCTTCTGCATGTCTTTTATAAAGACCTTTGTGATTTCACTGGGCCCACTCATATAAGCCAGGAAAATCTCT
GTGTCTCAGATCCTTAATTTAATTACACCTGCAAAGTCCGTTTTCTCGTGTAAAGTAACATATTCACAGGTTTCTGGAATTGGGACGTGG
ACATCTTCGGGGGACCATTACTCTGTCTGTCATACTCCCTGAGTGTGTAAGGGCCATCTCTTCAGAGCCTAATGTGTCATCCTACACAGA
GCAGGTGTTTCCTTATAAATTAAGTTGAATTAAATTACCCCTATGAAGCCACATAATCAATAATTCAGCTATAATAAACATTGCCGAATA
AATTAACAAAGGGAGGATAATGACTCCTTATGATGATGGATAGAAACACTGAAGAAAACCATTTTCAGAGGATTTACTGAATTTTCCTCT
CCAAGGAGCTTGTAATAGAAGGGTAAACCTCTAGTTTCTTGTCCAGCAGAGGAATAGGCTCATGTCTTTTGTTTTATTTTATTTTTTTGG
TGAGTCAGTATGGTTGGGTTAATCATATTCACATTAGATTCCATGTTGAAGAACAACTAATCAAAGAAGAAAATCATCAGGAATCAGGGT
GAGATTAACAGACCAAGGTCAGAAACATGGAGTTACAATTTTCCAAAAAAGCACGAAGTGAGATTAAAACCACAGTAAGTCTTAGTCTGA
CTGACAGGCTTTATACAGGCCCTCGGTAAGCAGTTGGGAGAACCCATGCCCACCACTGCTCTGTACGGTATCTGGCTGCTCAGAGCTCTC
TGATTCACAAAAGAGATCATCAAGAATTGACTCTGTGTTAAACTGTTTTTCACTTAGAATATGGACCCCCACCAATACATTCAATGAAGG
GTCATTAAGGAAGCTCTGATTAACACCAGGCCCATGCAGTTACTCCGCACATATAATCTGTGGGTATTATGTTGATTTGAACTTGCTTAG
CTGACTTAAAGCAGGGTTTCTCAAACTGTAGTATGCATCAGAATGACTTGGAAAGCTGGTTAAAAACGCAGATTGCTGGGTCCACCCAGC
TTCTGATGCAATAGGTCTGGGGTTAGAAATTTTGCTTTCTAATGAGTTCCCAGGTGATGCTGATGCCAATGATGTGAAGCCCGCTCTTCA
CATCCGTGAAAATCGCTGCCTTAAGGTGCTCTTAAATTGTTATAGATTGGTAGATCCTACCTTTCCATCACTGGTATGTTTTTTGAGAAA
AGGATCCTTTCTTTTCATTCTGTTATATTCATCCTATTACATAGGATGTTGGTTAGCACAGAGTGGGAGCTCTAGAAAGATTGTTGACCA
ATCATCTTATTGACTAGACCATCTTTCTAGAGTATAACTATTTTGGACACCTCAAAGATGAAGTCAGATAAGCTGGCAGTGACCTGATTA
ACGTTGTGGTAAGCAGATGCCACTGTGGCTGGGAAGTACCAAATCTTCTGTTGAGTGATTCAGTCTTCCTGACTAGATTTGCCTTCTAGT
GGGTGTATTAATAAGCGTTAGTTGATATGAATTAAATGTTGCAACTTTCTATGGGTAATAAGAGGATACCTTTATAGTTTCATGATGTGG
AGACCAAGATACATAAGAAAGCAAGAATGAGTCTCCGGGTGTTCCCTCTGATCAGCAAACATGAATTCATAATTTCATTTACTCTCATTT
TTGTAATGCACTCTGAGCAATCCTCCAGGCAGATCCTATTTACTAAGCTTCAGGCTTTTGTCCCATTTTATAATGCCCAAACACATGGAG
AAAACATTTTGTTGTTTTTAAAAACAGGTATGGGATTTCTGATATAATCAATTTTATTGACTTCTTGGGAGTTGTAATGATCTGTGACTC
ACTGCATAATATTGTAGTTTTATAGGGTGGCACATCACCCTGTGTAAAACAACTTTAATGACCTGAGGACTGATGAGTACAGGAAGTGAG
GTTTATCATGAGTAGCATTTATTAAGCATCTGCTAGAATCAAAGCACTGCATTAGCTACTAAGGTACAAAGTAAGACACAGTTTAATAAG
GAAGACAGGGCATCTACCCAAGTCAACAGTTCAGTGACATCTGTTATTTGAACCACACACCAATGCAACCGAAGTAAATGCTGAAAGGGT
GAGAAGAAGGAATAGATTACTATGCATTTTTGAGAGGATGAAGAAGGCTTCTTGGAGAAGGTTTCTGAAAAGAGATACGGAATTAAGAGA
AATAGAAAAGAGCACTGACGAAGCACTCAGGATGGCTATTCAAGGAATTGGGGATCCACAGCAGCTGTGCACAACCATCCCTAATGCCAG
AAAAATGGGGTAAGGGTGAAGGGAACTGGGTCTAGAGCTTTGCATGTTTTTTTCTGGTTAACCCTTAGAGTCACCCTGAAGGTGTGGATC
CCATCTTATAATAAGGTGAGGACACTGAGTCAGGAAACTAACTTGCTAAAATCAAGTCCTCCCAGTCCTCCCATCAGGTCCTTCCAGATC
TGGAGGAGCCAGGATTTGAACTCACATTTGTCTGACTTCAAAATCCATGCTTTTTCTTGTGTTCCAAATTGCACAATGGAGTCACTGCCA
GTTCAAGCTCCTATGAAAAGGGATGGATGTGAAAAGTCATTTGTTGATTCCACAGATTTTTAGTAGGTACCATGTCTCCTGCCTTTATCA
CTATCCTACTCCTCTGCTACAACTTCTCTGCTACAGGCACCCACTGCAGTTACTTGATATGAGTTAAATGAATCCATCCATCCAAACTTC
CATTCATTGAATAAATACTTAGCAATGGCTTCCTTTGTATCAGGCACTATTCTAGGAGCTGGGGCTACAGTGCAGATGGAAACCAGCAAA
GCTCACTGCCCTCATGGAGCTTATATGTAAGTGAATAAATCTCAGGGTGGTTCTCCTGTCATAGGTCCTGGCTCCTCTGCCAGCTCTTCC
AAATGGGTTCAGAGAGGTTTTCTCCTTGTCCTGTTGTGTAACTGATAATCCCATGGTGGACCTCACTTTGCTATTCATATGCACTAAGTA
GTTTATGGTGTGCTTTGTGGCTGGCAATTGTGACAGATTCTATTCTTCTATTGGTATGTGGTTTCTTTGGGGCATTTGTTTGGATACTGA
TGGCATCTTCCGGGGGTCTGAGGCACCTACACAAACCTCAGGTCACTATCACGTGATACTGGAGTTGCCTGTTAAATTATATTTCTTCTT
CCACAAAACTGCAGGTTCCCTGAGGGAAAGGTCTATGTCCTGCTCATTTTTGGATCCCTAATGGCTGGCACAGTACCTGGTGCATAATAT
GGTTCAACAAATATTTGTAAAATGAATGAATCAAATAGTCCTTCAAAGCATCTTCAGAATCAAGATTGTCATCTAGATTGCACCCGAAGT
TTATCTTTCTAGTATTCAGAATATAATCAATCATTGCTTAAATTATTCCATTTCATCATTCTTGAATAAAAGCTACTAATTTTAAATACT
AATATCTGAGATATCTTCGAAAAGAAGATTAGTCGTTGTATGTGTTGCTTATAAATTTTCTCTATGGTGGAAAATATTCCCAAACCATGT
CTAAGCAATGAAAAACCAGTGTTCTGGCAGGAAATAAACTGATGTTTGTTGTGTTTTGTATCTGTCTTCCCGTTCCAAATCATTTATATA
TACTTGATGGTCTGTGGGCTTGACTTGCAAGTATTTTCCTGGGAGACATTTTTATTCAAAAGACCTGTATTGCCTGCCAAACCTTCATTT
AAGAGACTCATTATGGATGTCATCTGCATCATTGCAAACTTTTCTGGTCGTCTCTATAAATAGCAAGATAATATTTACAGAGTTTTACAT
TGGCTCTTGAATTTTAAAATATTCTTATAGACAAACATTAATTGGAATGGGGGGTAAGGAGGTAGGAATGGCTTACTTGCGGAAATGCAG
GCTCATTGTTGTGTCTAGTAGGTGCTAGGTGCATTCACACATCTCTTAAGCTTTAAACAACCTATTGAGCCGGTTTCCATTTCCTTGATC
TATTAGATTTAAAAAAATGAAGCATAAAGGAGTTGGCTCTTGCCCTAAGTCATACTACTGATGGAATGAGAATACAAACCAAAAACACTT
TATTCAAGTCCAGGAAATATCTGCCTTGAAAAAGAATAACTTAAAAATTAAAAGTGTCCTCTATTTGAACATGAAAACAGCTAATAAAGA
TGTGTTATTTTATTTTATTATTATTAATTTTGTCCTCCCATATTGGCAAAGATAAAGCAATTGACAAAAATGGAATTCTTGTTCAATACT
GGCAGGAGTGAAAATTGGTAGAACCTTTCTAGAAGGCAATTTGGCAACATGTATGAAAACCTAAATGTTGATACACCTTTACCCAGCAGT
TTGTTTAGGAATTTATCCTAATGAATAAAAGTTGTCCAAGTCTTCAAACATGAGCCCAAAGGTATATTTCATGATGTTTATGATATTAAA
ACATTGGAAACAACTGAAACATCCTTCAGTAAAAGATGGATTAAATAAATTCCATGCAGTTGTCATTTAAAAATATTTAGATATATGTTT
ATTGCTATGGATATATGTTCCCAAAATATTATTGAATCAAAAAGTAGACTACAGGATATATGTTGAATATGAGCTCATTTATAACATTGA
ATATTTTAAGATAATGTATGTTTCATAGAGAGATCTTCACCAAATGTTAAGGATTTTTTTTTCTGGGCTGTGGTATTTGGGTGATCTTTA

>In-frame_ENST00000346027_ENST00000261233_TCGA-FD-A6TG_TLK2_chr17_60679541_+_IRAK3_chr12_66620502_length(amino acids)=1048AA_start in transcript=121_stop in transcript=3267
MPGRGVAALRRGPGSAPGLPRGRAERSAAGSGRGPSREERGAAAAAAAAEMMEELHSLDPRRQELLEARFTGVGVSKGPLNSESSNQSLC
SVGSLSDKEVETPEKKQNDQRNRKRKAEPYETSQGKGTPRGHKISDYFEFAGGSAPGTSPGRSVPPVARSSPQHSLSNPLPRRVEQPLYG
LDGSAAKEATEEQSALPTLMSVMLAKPRLDTEQLAQRGAGLCFTFVSAQQNSPSSTGSGNTEHSCSSQKQISIQHRQTQSDLTIEKISAL
ENSKNSDLEKKEGRIDDLLRANCDLRRQIDEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFTTVRHGASFTE
QWTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKPPAMGQAPPATNEQKQRKSKTNGAENETLTLAEYHEQEEIFKLRLGHLKKEEAE
IQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHAC
REYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILLVN
GTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWFHHPNILELAAYFTETEKFCLIYPYMRNGTLFDRLQCVGDTAPLPWHIRI
GILIGISKAIHYLHNVQPCSVICGSISSANILLDDQFQPKLTDFAMAHFRSHLEHQSCTINMTSSSSKHLWYMPEEYIRQGKLSIKTDVY
SFGIVIMEVLTGCRVVLDDPKHIQLRDLLRELMEKRGLDSCLSFLDKKVPPCPRNFSAKLFCLAGRCAATRAKLRPSMDEVLNTLESTQA
SLYFAEDPPTSLKSFRCPSPLFLENVPSIPVEDDESQNNNLLPSDEGLRIDRMTQKTPFECSQSEVMFLSLDKKPESKRNEEACNMPSSS

--------------------------------------------------------------
>In-frame_ENST00000343388_ENST00000261233_TCGA-FD-A6TG_TLK2_chr17_60679541_+_IRAK3_chr12_66620502_length(transcript)=9498nt_BP=1909nt
CCGGGCGGGGGGTTGCGGCGCTCAGGAGAGGCCCCGGCTCCGCCCCGGGCCTGCCCAGGGGGAGAGCGGAGCGGTCCGCAGCCGGGTCGG
GTCGGGGCCCCTCCCGGGAGGAGCGTGGAGCGGCGGCGGCGGCGGCGGCAGCAGAAATGATGGAAGAATTGCATAGCCTGGACCCACGAC
GGCAGGAATTATTGGAGGCCAGGTTTACTGGAGTAGGTGTTAGTAAGGGACCACTTAATAGTGAGTCTTCCAACCAGAGCTTGTGCAGCG
TCGGATCCTTGAGTGATAAAGAAGTAGAGACTCCCGAGAAAAAGCAGAATGACCAGCGAAATCGGAAAAGAAAAGCTGAACCATATGAAA
CTAGCCAAGGGAAAGGCACTCCTAGGGGACATAAAATTAGTGATTACTTTGAGCGACGAGTAGAACAGCCCCTCTATGGTTTAGATGGCA
GTGCTGCAAAGGAGGCAACGGAGGAGCAGTCTGCTCTGCCAACCCTCATGTCAGTGATGCTAGCAAAACCTCGGCTTGACACAGAGCAGC
TGGCGCAAAGGGGAGCTGGCCTCTGCTTCACTTTTGTTTCAGCTCAGCAAAACAGTCCCTCATCTACGGGATCTGGCAACACAGAGCATT
CCTGCAGCTCCCAAAAACAGATCTCCATCCAGCACAGACAGACCCAGTCCGACCTCACAATAGAAAAAATATCTGCACTAGAAAACAGTA
AGAATTCTGACTTAGAGAAGAAGGAGGGAAGAATAGATGATTTATTAAGAGCCAACTGTGATTTGAGACGGCAGATTGATGAACAGCAAA
AGATGCTAGAGAAATACAAGGAACGATTAAATAGATGTGTGACAATGAGCAAGAAACTCCTTATAGAAAAGTCAAAACAAGAGAAGATGG
CGTGTAGAGATAAGAGCATGCAAGACCGCTTGAGACTGGGCCACTTTACTACTGTCCGACACGGAGCCTCATTTACTGAACAGTGGACAG
ATGGTTATGCTTTTCAGAATCTTATCAAGCAACAGGAAAGGATAAATTCACAGAGGGAAGAGATAGAAAGACAACGGAAAATGTTAGCAA
AGCGGAAACCTCCTGCCATGGGTCAGGCCCCTCCTGCAACCAATGAGCAGAAACAGCGGAAAAGCAAGACCAATGGAGCTGAAAATGAAA
CGTTAACGTTAGCAGAATACCATGAACAAGAAGAAATCTTCAAACTCAGATTAGGTCATCTTAAAAAGGAGGAAGCAGAGATCCAGGCAG
AGCTGGAGAGACTAGAAAGGGTTAGAAATCTACATATCAGGGAACTAAAAAGGATACATAATGAAGATAATTCACAATTTAAAGATCATC
CAACGCTAAATGACAGATATTTGTTGTTACATCTTTTGGGTAGAGGAGGTTTCAGTGAAGTTTACAAGGCATTTGATCTAACAGAGCAAA
GATACGTAGCTGTGAAAATTCACCAGTTAAATAAAAACTGGAGAGATGAGAAAAAGGAGAATTACCACAAGCATGCATGTAGGGAATACC
GGATTCATAAAGAGCTGGATCATCCCAGAATAGTTAAGCTGTATGATTACTTTTCACTGGATACTGACTCGTTTTGTACAGTATTAGAAT
ACTGTGAGGGAAATGATCTGGACTTCTACCTGAAACAGCACAAATTAATGTCGGAGAAAGAGGCCCGGTCCATTATCATGCAGATTGTGA
ATGCTTTAAAGTACTTAAATGAAATAAAACCTCCCATCATACACTATGACCTCAAACCAGGTAATATTCTTTTAGTAAATGGTACAGCGT
GTGGAGAGATAAAAATTACAGATTTTGGTCTTTCGAAGATCATGGATGATGATAGCTACAATTCAGTGGATGGCATGGAGCTAACATCAC
AAGGTGCTGGTACTTATTGGTTTCATCACCCAAACATACTAGAGTTGGCTGCATATTTTACAGAGACTGAGAAGTTCTGTCTGATTTATC
CATACATGAGAAATGGAACACTTTTTGACAGATTGCAGTGTGTAGGTGACACGGCCCCACTCCCTTGGCACATTCGAATCGGTATATTAA
TAGGAATATCCAAAGCCATTCACTACCTGCACAACGTTCAACCATGCTCGGTCATCTGTGGCAGTATATCAAGTGCAAACATCCTTTTGG
ATGATCAGTTTCAACCCAAACTAACTGATTTTGCCATGGCACACTTCCGGTCCCACCTAGAACATCAGAGTTGTACCATAAATATGACCA
GCAGCAGCAGTAAACATCTGTGGTACATGCCAGAAGAGTACATCAGACAGGGGAAACTTTCCATTAAAACAGATGTCTACAGCTTTGGAA
TTGTAATAATGGAAGTTCTAACAGGATGTAGAGTAGTGTTAGATGATCCAAAACATATCCAGCTGCGGGATCTCCTTAGAGAATTGATGG
AGAAGAGAGGCCTGGATTCATGTCTCTCATTTCTAGATAAGAAAGTGCCTCCCTGCCCTCGGAATTTCTCTGCCAAGCTCTTCTGTTTGG
CAGGCCGGTGTGCTGCAACGCGGGCAAAGTTAAGACCATCAATGGATGAAGTTTTAAATACTCTTGAAAGTACTCAAGCCAGCTTGTATT
TTGCTGAAGATCCTCCCACATCACTAAAGTCCTTCAGGTGTCCTTCTCCTCTATTCCTGGAGAATGTACCAAGTATTCCAGTGGAAGATG
ATGAAAGCCAGAATAACAATTTACTACCTTCTGATGAAGGCCTGAGGATAGACAGAATGACTCAGAAAACTCCTTTTGAATGCAGCCAGT
CTGAGGTTATGTTTCTGAGCTTGGACAAAAAGCCAGAGAGCAAGAGAAATGAGGAAGCTTGCAACATGCCCAGTTCTTCTTGTGAAGAAA
GTTGGTTCCCAAAGTATATAGTTCCATCCCAGGACTTAAGGCCCTATAAGGTAAATATAGATCCTTCTTCAGAAGCTCCAGGGCATTCTT
GCAGGAGCAGGCCAGTGGAGAGCAGCTGTTCCTCCAAATTTTCCTGGGATGAATATGAACAGTACAAAAAAGAATAAATTCTACCAGAAG
ATAAAGAAAAAAGCAAGTATTGCATAGGCACCTGAGCATAGGTATGACCTTGGGAAGACATTGGCTCCATAAGCAATGCCAAGAGAATGA
TCAATAGTGAGTTTGGGTGATGCAGATAAACAATCTGGATAATTCCATTTCTTTTTTCCCAAACCCTCAAACAGAGTGCCTTAAAAAATT
GTTTTATCAGGATAATTGTCTCATGACCAAATCCACGCTCAATTAGAGCCATTCAAAATTCCTTAAGATCATGGGTTCTGACTTCAGCCA
AACAAAACAATCAAAACCTACCAAAAAGGGACTGGATTGTAATGTCCTCTCCATCATCCTCAGTGTGAGTCCTCAGAGCCTCCATCTGCC
AAGAACATTCAGTTGGATTCCATCGTTTGGTTTAGCTTGCTTGCACGGGTTGTAGGAAATGTCTAATTTGTAAATGTTAATAGATACCTT
TGGAAAGAATCACCTTGTTATTCTGATTGACCCCTCTTGTTTTTTGGTTAATCCCTGACTAGCCTGCTTGTCTGAAAATGAGCCAGGTTC
ACCCTTAGCTACGGCATGCTCTGGGTTGAAAGGGGATTTCTTCCCAAGATCTATCCTAAACTCTTAGGACAGTTTATCCTGTATTGACTA
TTATTACAGCTTTTTAAAAACAGACTTAGTGACCTATTATATCTTAAGGAGACTATGTGAAATGTCCATCAAGTAATTTTTATTCCTGAG
AAAATGGCTGGTCAAGGGCCTAGGTCAGCTTTTTGTTTAATCTACACCTTTCAACTCTGGGCCTTCATTCCTGCTGTTTCTTGGATCTCC
CTCTTTTGAAATCCTACCAATCATCAGAGCTCTACAAAACAGCCACCTCCTGGAAGCTTCCCTAATCTCTACAACCAGAAGTACTCCCTT
TATCAGTATTTCCACAGCAATTTCTTTGTATTTCTATTTTATATTTATCACTTTCTGAATTATATCAAAGCTGCTTGTCTTATCTCTTTT
TTTTTTTGAGACGGAGTCTCGCTCTGTCATCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACCGCAAGGTCTGCCTCCCGGGTTCAC
GCCATTCTCCTGCCTCAGCCTCCCGAGTAAAGGTGGGACTACAGGCGCCCGCCACTACGCCCGGCTAATTTTTTGTATTTTTAGTAGAGA
CGGGGTTTCACCATGTTAGGCAGGATGGTCTCGATCTCCTGACCTCATGATCCGCCTGCCTGGCCTCCCAAAGTGCTGGGATTACAGGCG
TGAGCCACCGCGCCCAGCCTTCATCTCTTTTACTAGGTTGTAAACTCCCTATATTAGTTTTCTATTGTTTTTGTAACACATTATCACAAA
TTTAGTGACTTAAAGTAACATAAATTAATTATTTTGCAGTTCTGGAGGTCAGAATTCCTTAGCATTCTTTCTGGAGGCTGTTGGGGAGAA
CTCACTGCCTTGCCTTTTCCAGCTTCTAGAGGCCACCTGCCTTCTTTGGCTCATGGCCTCTTCCTCCGTCTTCAAAGCCAGCAACGTGAC
ATTTCAGATCTCCCTCTCTCTGTCTGTCTCACCGCATCTCTTCACTACCCTCTTCCTCTCATTCTGGCCCTTCTGCATGTCTTTTATAAA
GACCTTTGTGATTTCACTGGGCCCACTCATATAAGCCAGGAAAATCTCTGTGTCTCAGATCCTTAATTTAATTACACCTGCAAAGTCCGT
TTTCTCGTGTAAAGTAACATATTCACAGGTTTCTGGAATTGGGACGTGGACATCTTCGGGGGACCATTACTCTGTCTGTCATACTCCCTG
AGTGTGTAAGGGCCATCTCTTCAGAGCCTAATGTGTCATCCTACACAGAGCAGGTGTTTCCTTATAAATTAAGTTGAATTAAATTACCCC
TATGAAGCCACATAATCAATAATTCAGCTATAATAAACATTGCCGAATAAATTAACAAAGGGAGGATAATGACTCCTTATGATGATGGAT
AGAAACACTGAAGAAAACCATTTTCAGAGGATTTACTGAATTTTCCTCTCCAAGGAGCTTGTAATAGAAGGGTAAACCTCTAGTTTCTTG
TCCAGCAGAGGAATAGGCTCATGTCTTTTGTTTTATTTTATTTTTTTGGTGAGTCAGTATGGTTGGGTTAATCATATTCACATTAGATTC
CATGTTGAAGAACAACTAATCAAAGAAGAAAATCATCAGGAATCAGGGTGAGATTAACAGACCAAGGTCAGAAACATGGAGTTACAATTT
TCCAAAAAAGCACGAAGTGAGATTAAAACCACAGTAAGTCTTAGTCTGACTGACAGGCTTTATACAGGCCCTCGGTAAGCAGTTGGGAGA
ACCCATGCCCACCACTGCTCTGTACGGTATCTGGCTGCTCAGAGCTCTCTGATTCACAAAAGAGATCATCAAGAATTGACTCTGTGTTAA
ACTGTTTTTCACTTAGAATATGGACCCCCACCAATACATTCAATGAAGGGTCATTAAGGAAGCTCTGATTAACACCAGGCCCATGCAGTT
ACTCCGCACATATAATCTGTGGGTATTATGTTGATTTGAACTTGCTTAGCTGACTTAAAGCAGGGTTTCTCAAACTGTAGTATGCATCAG
AATGACTTGGAAAGCTGGTTAAAAACGCAGATTGCTGGGTCCACCCAGCTTCTGATGCAATAGGTCTGGGGTTAGAAATTTTGCTTTCTA
ATGAGTTCCCAGGTGATGCTGATGCCAATGATGTGAAGCCCGCTCTTCACATCCGTGAAAATCGCTGCCTTAAGGTGCTCTTAAATTGTT
ATAGATTGGTAGATCCTACCTTTCCATCACTGGTATGTTTTTTGAGAAAAGGATCCTTTCTTTTCATTCTGTTATATTCATCCTATTACA
TAGGATGTTGGTTAGCACAGAGTGGGAGCTCTAGAAAGATTGTTGACCAATCATCTTATTGACTAGACCATCTTTCTAGAGTATAACTAT
TTTGGACACCTCAAAGATGAAGTCAGATAAGCTGGCAGTGACCTGATTAACGTTGTGGTAAGCAGATGCCACTGTGGCTGGGAAGTACCA
AATCTTCTGTTGAGTGATTCAGTCTTCCTGACTAGATTTGCCTTCTAGTGGGTGTATTAATAAGCGTTAGTTGATATGAATTAAATGTTG
CAACTTTCTATGGGTAATAAGAGGATACCTTTATAGTTTCATGATGTGGAGACCAAGATACATAAGAAAGCAAGAATGAGTCTCCGGGTG
TTCCCTCTGATCAGCAAACATGAATTCATAATTTCATTTACTCTCATTTTTGTAATGCACTCTGAGCAATCCTCCAGGCAGATCCTATTT
ACTAAGCTTCAGGCTTTTGTCCCATTTTATAATGCCCAAACACATGGAGAAAACATTTTGTTGTTTTTAAAAACAGGTATGGGATTTCTG
ATATAATCAATTTTATTGACTTCTTGGGAGTTGTAATGATCTGTGACTCACTGCATAATATTGTAGTTTTATAGGGTGGCACATCACCCT
GTGTAAAACAACTTTAATGACCTGAGGACTGATGAGTACAGGAAGTGAGGTTTATCATGAGTAGCATTTATTAAGCATCTGCTAGAATCA
AAGCACTGCATTAGCTACTAAGGTACAAAGTAAGACACAGTTTAATAAGGAAGACAGGGCATCTACCCAAGTCAACAGTTCAGTGACATC
TGTTATTTGAACCACACACCAATGCAACCGAAGTAAATGCTGAAAGGGTGAGAAGAAGGAATAGATTACTATGCATTTTTGAGAGGATGA
AGAAGGCTTCTTGGAGAAGGTTTCTGAAAAGAGATACGGAATTAAGAGAAATAGAAAAGAGCACTGACGAAGCACTCAGGATGGCTATTC
AAGGAATTGGGGATCCACAGCAGCTGTGCACAACCATCCCTAATGCCAGAAAAATGGGGTAAGGGTGAAGGGAACTGGGTCTAGAGCTTT
GCATGTTTTTTTCTGGTTAACCCTTAGAGTCACCCTGAAGGTGTGGATCCCATCTTATAATAAGGTGAGGACACTGAGTCAGGAAACTAA
CTTGCTAAAATCAAGTCCTCCCAGTCCTCCCATCAGGTCCTTCCAGATCTGGAGGAGCCAGGATTTGAACTCACATTTGTCTGACTTCAA
AATCCATGCTTTTTCTTGTGTTCCAAATTGCACAATGGAGTCACTGCCAGTTCAAGCTCCTATGAAAAGGGATGGATGTGAAAAGTCATT
TGTTGATTCCACAGATTTTTAGTAGGTACCATGTCTCCTGCCTTTATCACTATCCTACTCCTCTGCTACAACTTCTCTGCTACAGGCACC
CACTGCAGTTACTTGATATGAGTTAAATGAATCCATCCATCCAAACTTCCATTCATTGAATAAATACTTAGCAATGGCTTCCTTTGTATC
AGGCACTATTCTAGGAGCTGGGGCTACAGTGCAGATGGAAACCAGCAAAGCTCACTGCCCTCATGGAGCTTATATGTAAGTGAATAAATC
TCAGGGTGGTTCTCCTGTCATAGGTCCTGGCTCCTCTGCCAGCTCTTCCAAATGGGTTCAGAGAGGTTTTCTCCTTGTCCTGTTGTGTAA
CTGATAATCCCATGGTGGACCTCACTTTGCTATTCATATGCACTAAGTAGTTTATGGTGTGCTTTGTGGCTGGCAATTGTGACAGATTCT
ATTCTTCTATTGGTATGTGGTTTCTTTGGGGCATTTGTTTGGATACTGATGGCATCTTCCGGGGGTCTGAGGCACCTACACAAACCTCAG
GTCACTATCACGTGATACTGGAGTTGCCTGTTAAATTATATTTCTTCTTCCACAAAACTGCAGGTTCCCTGAGGGAAAGGTCTATGTCCT
GCTCATTTTTGGATCCCTAATGGCTGGCACAGTACCTGGTGCATAATATGGTTCAACAAATATTTGTAAAATGAATGAATCAAATAGTCC
TTCAAAGCATCTTCAGAATCAAGATTGTCATCTAGATTGCACCCGAAGTTTATCTTTCTAGTATTCAGAATATAATCAATCATTGCTTAA
ATTATTCCATTTCATCATTCTTGAATAAAAGCTACTAATTTTAAATACTAATATCTGAGATATCTTCGAAAAGAAGATTAGTCGTTGTAT
GTGTTGCTTATAAATTTTCTCTATGGTGGAAAATATTCCCAAACCATGTCTAAGCAATGAAAAACCAGTGTTCTGGCAGGAAATAAACTG
ATGTTTGTTGTGTTTTGTATCTGTCTTCCCGTTCCAAATCATTTATATATACTTGATGGTCTGTGGGCTTGACTTGCAAGTATTTTCCTG
GGAGACATTTTTATTCAAAAGACCTGTATTGCCTGCCAAACCTTCATTTAAGAGACTCATTATGGATGTCATCTGCATCATTGCAAACTT
TTCTGGTCGTCTCTATAAATAGCAAGATAATATTTACAGAGTTTTACATTGGCTCTTGAATTTTAAAATATTCTTATAGACAAACATTAA
TTGGAATGGGGGGTAAGGAGGTAGGAATGGCTTACTTGCGGAAATGCAGGCTCATTGTTGTGTCTAGTAGGTGCTAGGTGCATTCACACA
TCTCTTAAGCTTTAAACAACCTATTGAGCCGGTTTCCATTTCCTTGATCTATTAGATTTAAAAAAATGAAGCATAAAGGAGTTGGCTCTT
GCCCTAAGTCATACTACTGATGGAATGAGAATACAAACCAAAAACACTTTATTCAAGTCCAGGAAATATCTGCCTTGAAAAAGAATAACT
TAAAAATTAAAAGTGTCCTCTATTTGAACATGAAAACAGCTAATAAAGATGTGTTATTTTATTTTATTATTATTAATTTTGTCCTCCCAT
ATTGGCAAAGATAAAGCAATTGACAAAAATGGAATTCTTGTTCAATACTGGCAGGAGTGAAAATTGGTAGAACCTTTCTAGAAGGCAATT
TGGCAACATGTATGAAAACCTAAATGTTGATACACCTTTACCCAGCAGTTTGTTTAGGAATTTATCCTAATGAATAAAAGTTGTCCAAGT
CTTCAAACATGAGCCCAAAGGTATATTTCATGATGTTTATGATATTAAAACATTGGAAACAACTGAAACATCCTTCAGTAAAAGATGGAT
TAAATAAATTCCATGCAGTTGTCATTTAAAAATATTTAGATATATGTTTATTGCTATGGATATATGTTCCCAAAATATTATTGAATCAAA
AAGTAGACTACAGGATATATGTTGAATATGAGCTCATTTATAACATTGAATATTTTAAGATAATGTATGTTTCATAGAGAGATCTTCACC
AAATGTTAAGGATTTTTTTTTCTGGGCTGTGGTATTTGGGTGATCTTTACATTCTTCAGACTCATGTGTGTTTGAAACTTTTTATAATGA

>In-frame_ENST00000343388_ENST00000261233_TCGA-FD-A6TG_TLK2_chr17_60679541_+_IRAK3_chr12_66620502_length(amino acids)=998AA_start in transcript=50_stop in transcript=3046
MPRGRAERSAAGSGRGPSREERGAAAAAAAAEMMEELHSLDPRRQELLEARFTGVGVSKGPLNSESSNQSLCSVGSLSDKEVETPEKKQN
DQRNRKRKAEPYETSQGKGTPRGHKISDYFERRVEQPLYGLDGSAAKEATEEQSALPTLMSVMLAKPRLDTEQLAQRGAGLCFTFVSAQQ
NSPSSTGSGNTEHSCSSQKQISIQHRQTQSDLTIEKISALENSKNSDLEKKEGRIDDLLRANCDLRRQIDEQQKMLEKYKERLNRCVTMS
KKLLIEKSKQEKMACRDKSMQDRLRLGHFTTVRHGASFTEQWTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKPPAMGQAPPATNEQ
KQRKSKTNGAENETLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGG
FSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLM
SEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWFHHPNILELA
AYFTETEKFCLIYPYMRNGTLFDRLQCVGDTAPLPWHIRIGILIGISKAIHYLHNVQPCSVICGSISSANILLDDQFQPKLTDFAMAHFR
SHLEHQSCTINMTSSSSKHLWYMPEEYIRQGKLSIKTDVYSFGIVIMEVLTGCRVVLDDPKHIQLRDLLRELMEKRGLDSCLSFLDKKVP
PCPRNFSAKLFCLAGRCAATRAKLRPSMDEVLNTLESTQASLYFAEDPPTSLKSFRCPSPLFLENVPSIPVEDDESQNNNLLPSDEGLRI
DRMTQKTPFECSQSEVMFLSLDKKPESKRNEEACNMPSSSCEESWFPKYIVPSQDLRPYKVNIDPSSEAPGHSCRSRPVESSCSSKFSWD

--------------------------------------------------------------
>In-frame_ENST00000542523_ENST00000261233_TCGA-FD-A6TG_TLK2_chr17_60679541_+_IRAK3_chr12_66620502_length(transcript)=9377nt_BP=1788nt
AAGGAATTTTCTTTTTGCAGCAGAAATGATGGAAGAATTGCATAGCCTGGACCCACGACGGCAGGAATTATTGGAGGCCAGGTTTACTGG
AGTAGGTGTTAGTAAGGGACCACTTAATAGTGAGTCTTCCAACCAGAGCTTGTGCAGCGTCGGATCCTTGAGTGATAAAGAAGTAGAGAC
TCCCGAGAAAAAGCAGAATGACCAGCGAAATCGGAAAAGAAAAGCTGAACCATATGAAACTAGCCAAGGGAAAGGCACTCCTAGGGGACA
TAAAATTAGTGATTACTTTGAGCGACGAGTAGAACAGCCCCTCTATGGTTTAGATGGCAGTGCTGCAAAGGAGGCAACGGAGGAGCAGTC
TGCTCTGCCAACCCTCATGTCAGTGATGCTAGCAAAACCTCGGCTTGACACAGAGCAGCTGGCGCAAAGGGGAGCTGGCCTCTGCTTCAC
TTTTGTTTCAGCTCAGCAAAACAGTCCCTCATCTACGGGATCTGGCAACACAGAGCATTCCTGCAGCTCCCAAAAACAGATCTCCATCCA
GCACAGACAGACCCAGTCCGACCTCACAATAGAAAAAATATCTGCACTAGAAAACAGTAAGAATTCTGACTTAGAGAAGAAGGAGGGAAG
AATAGATGATTTATTAAGAGCCAACTGTGATTTGAGACGGCAGATTGATGAACAGCAAAAGATGCTAGAGAAATACAAGGAACGATTAAA
TAGATGTGTGACAATGAGCAAGAAACTCCTTATAGAAAAGTCAAAACAAGAGAAGATGGCGTGTAGAGATAAGAGCATGCAAGACCGCTT
GAGACTGGGCCACTTTACTACTGTCCGACACGGAGCCTCATTTACTGAACAGTGGACAGATGGTTATGCTTTTCAGAATCTTATCAAGCA
ACAGGAAAGGATAAATTCACAGAGGGAAGAGATAGAAAGACAACGGAAAATGTTAGCAAAGCGGAAACCTCCTGCCATGGGTCAGGCCCC
TCCTGCAACCAATGAGCAGAAACAGCGGAAAAGCAAGACCAATGGAGCTGAAAATGAAACGTTAACGTTAGCAGAATACCATGAACAAGA
AGAAATCTTCAAACTCAGATTAGGTCATCTTAAAAAGGAGGAAGCAGAGATCCAGGCAGAGCTGGAGAGACTAGAAAGGGTTAGAAATCT
ACATATCAGGGAACTAAAAAGGATACATAATGAAGATAATTCACAATTTAAAGATCATCCAACGCTAAATGACAGATATTTGTTGTTACA
TCTTTTGGGTAGAGGAGGTTTCAGTGAAGTTTACAAGGCATTTGATCTAACAGAGCAAAGATACGTAGCTGTGAAAATTCACCAGTTAAA
TAAAAACTGGAGAGATGAGAAAAAGGAGAATTACCACAAGCATGCATGTAGGGAATACCGGATTCATAAAGAGCTGGATCATCCCAGAAT
AGTTAAGCTGTATGATTACTTTTCACTGGATACTGACTCGTTTTGTACAGTATTAGAATACTGTGAGGGAAATGATCTGGACTTCTACCT
GAAACAGCACAAATTAATGTCGGAGAAAGAGGCCCGGTCCATTATCATGCAGATTGTGAATGCTTTAAAGTACTTAAATGAAATAAAACC
TCCCATCATACACTATGACCTCAAACCAGGTAATATTCTTTTAGTAAATGGTACAGCGTGTGGAGAGATAAAAATTACAGATTTTGGTCT
TTCGAAGATCATGGATGATGATAGCTACAATTCAGTGGATGGCATGGAGCTAACATCACAAGGTGCTGGTACTTATTGGTTTCATCACCC
AAACATACTAGAGTTGGCTGCATATTTTACAGAGACTGAGAAGTTCTGTCTGATTTATCCATACATGAGAAATGGAACACTTTTTGACAG
ATTGCAGTGTGTAGGTGACACGGCCCCACTCCCTTGGCACATTCGAATCGGTATATTAATAGGAATATCCAAAGCCATTCACTACCTGCA
CAACGTTCAACCATGCTCGGTCATCTGTGGCAGTATATCAAGTGCAAACATCCTTTTGGATGATCAGTTTCAACCCAAACTAACTGATTT
TGCCATGGCACACTTCCGGTCCCACCTAGAACATCAGAGTTGTACCATAAATATGACCAGCAGCAGCAGTAAACATCTGTGGTACATGCC
AGAAGAGTACATCAGACAGGGGAAACTTTCCATTAAAACAGATGTCTACAGCTTTGGAATTGTAATAATGGAAGTTCTAACAGGATGTAG
AGTAGTGTTAGATGATCCAAAACATATCCAGCTGCGGGATCTCCTTAGAGAATTGATGGAGAAGAGAGGCCTGGATTCATGTCTCTCATT
TCTAGATAAGAAAGTGCCTCCCTGCCCTCGGAATTTCTCTGCCAAGCTCTTCTGTTTGGCAGGCCGGTGTGCTGCAACGCGGGCAAAGTT
AAGACCATCAATGGATGAAGTTTTAAATACTCTTGAAAGTACTCAAGCCAGCTTGTATTTTGCTGAAGATCCTCCCACATCACTAAAGTC
CTTCAGGTGTCCTTCTCCTCTATTCCTGGAGAATGTACCAAGTATTCCAGTGGAAGATGATGAAAGCCAGAATAACAATTTACTACCTTC
TGATGAAGGCCTGAGGATAGACAGAATGACTCAGAAAACTCCTTTTGAATGCAGCCAGTCTGAGGTTATGTTTCTGAGCTTGGACAAAAA
GCCAGAGAGCAAGAGAAATGAGGAAGCTTGCAACATGCCCAGTTCTTCTTGTGAAGAAAGTTGGTTCCCAAAGTATATAGTTCCATCCCA
GGACTTAAGGCCCTATAAGGTAAATATAGATCCTTCTTCAGAAGCTCCAGGGCATTCTTGCAGGAGCAGGCCAGTGGAGAGCAGCTGTTC
CTCCAAATTTTCCTGGGATGAATATGAACAGTACAAAAAAGAATAAATTCTACCAGAAGATAAAGAAAAAAGCAAGTATTGCATAGGCAC
CTGAGCATAGGTATGACCTTGGGAAGACATTGGCTCCATAAGCAATGCCAAGAGAATGATCAATAGTGAGTTTGGGTGATGCAGATAAAC
AATCTGGATAATTCCATTTCTTTTTTCCCAAACCCTCAAACAGAGTGCCTTAAAAAATTGTTTTATCAGGATAATTGTCTCATGACCAAA
TCCACGCTCAATTAGAGCCATTCAAAATTCCTTAAGATCATGGGTTCTGACTTCAGCCAAACAAAACAATCAAAACCTACCAAAAAGGGA
CTGGATTGTAATGTCCTCTCCATCATCCTCAGTGTGAGTCCTCAGAGCCTCCATCTGCCAAGAACATTCAGTTGGATTCCATCGTTTGGT
TTAGCTTGCTTGCACGGGTTGTAGGAAATGTCTAATTTGTAAATGTTAATAGATACCTTTGGAAAGAATCACCTTGTTATTCTGATTGAC
CCCTCTTGTTTTTTGGTTAATCCCTGACTAGCCTGCTTGTCTGAAAATGAGCCAGGTTCACCCTTAGCTACGGCATGCTCTGGGTTGAAA
GGGGATTTCTTCCCAAGATCTATCCTAAACTCTTAGGACAGTTTATCCTGTATTGACTATTATTACAGCTTTTTAAAAACAGACTTAGTG
ACCTATTATATCTTAAGGAGACTATGTGAAATGTCCATCAAGTAATTTTTATTCCTGAGAAAATGGCTGGTCAAGGGCCTAGGTCAGCTT
TTTGTTTAATCTACACCTTTCAACTCTGGGCCTTCATTCCTGCTGTTTCTTGGATCTCCCTCTTTTGAAATCCTACCAATCATCAGAGCT
CTACAAAACAGCCACCTCCTGGAAGCTTCCCTAATCTCTACAACCAGAAGTACTCCCTTTATCAGTATTTCCACAGCAATTTCTTTGTAT
TTCTATTTTATATTTATCACTTTCTGAATTATATCAAAGCTGCTTGTCTTATCTCTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCATC
CAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACCGCAAGGTCTGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAAA
GGTGGGACTACAGGCGCCCGCCACTACGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTAGGCAGGATGGTCT
CGATCTCCTGACCTCATGATCCGCCTGCCTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCAGCCTTCATCTCTTTT
ACTAGGTTGTAAACTCCCTATATTAGTTTTCTATTGTTTTTGTAACACATTATCACAAATTTAGTGACTTAAAGTAACATAAATTAATTA
TTTTGCAGTTCTGGAGGTCAGAATTCCTTAGCATTCTTTCTGGAGGCTGTTGGGGAGAACTCACTGCCTTGCCTTTTCCAGCTTCTAGAG
GCCACCTGCCTTCTTTGGCTCATGGCCTCTTCCTCCGTCTTCAAAGCCAGCAACGTGACATTTCAGATCTCCCTCTCTCTGTCTGTCTCA
CCGCATCTCTTCACTACCCTCTTCCTCTCATTCTGGCCCTTCTGCATGTCTTTTATAAAGACCTTTGTGATTTCACTGGGCCCACTCATA
TAAGCCAGGAAAATCTCTGTGTCTCAGATCCTTAATTTAATTACACCTGCAAAGTCCGTTTTCTCGTGTAAAGTAACATATTCACAGGTT
TCTGGAATTGGGACGTGGACATCTTCGGGGGACCATTACTCTGTCTGTCATACTCCCTGAGTGTGTAAGGGCCATCTCTTCAGAGCCTAA
TGTGTCATCCTACACAGAGCAGGTGTTTCCTTATAAATTAAGTTGAATTAAATTACCCCTATGAAGCCACATAATCAATAATTCAGCTAT
AATAAACATTGCCGAATAAATTAACAAAGGGAGGATAATGACTCCTTATGATGATGGATAGAAACACTGAAGAAAACCATTTTCAGAGGA
TTTACTGAATTTTCCTCTCCAAGGAGCTTGTAATAGAAGGGTAAACCTCTAGTTTCTTGTCCAGCAGAGGAATAGGCTCATGTCTTTTGT
TTTATTTTATTTTTTTGGTGAGTCAGTATGGTTGGGTTAATCATATTCACATTAGATTCCATGTTGAAGAACAACTAATCAAAGAAGAAA
ATCATCAGGAATCAGGGTGAGATTAACAGACCAAGGTCAGAAACATGGAGTTACAATTTTCCAAAAAAGCACGAAGTGAGATTAAAACCA
CAGTAAGTCTTAGTCTGACTGACAGGCTTTATACAGGCCCTCGGTAAGCAGTTGGGAGAACCCATGCCCACCACTGCTCTGTACGGTATC
TGGCTGCTCAGAGCTCTCTGATTCACAAAAGAGATCATCAAGAATTGACTCTGTGTTAAACTGTTTTTCACTTAGAATATGGACCCCCAC
CAATACATTCAATGAAGGGTCATTAAGGAAGCTCTGATTAACACCAGGCCCATGCAGTTACTCCGCACATATAATCTGTGGGTATTATGT
TGATTTGAACTTGCTTAGCTGACTTAAAGCAGGGTTTCTCAAACTGTAGTATGCATCAGAATGACTTGGAAAGCTGGTTAAAAACGCAGA
TTGCTGGGTCCACCCAGCTTCTGATGCAATAGGTCTGGGGTTAGAAATTTTGCTTTCTAATGAGTTCCCAGGTGATGCTGATGCCAATGA
TGTGAAGCCCGCTCTTCACATCCGTGAAAATCGCTGCCTTAAGGTGCTCTTAAATTGTTATAGATTGGTAGATCCTACCTTTCCATCACT
GGTATGTTTTTTGAGAAAAGGATCCTTTCTTTTCATTCTGTTATATTCATCCTATTACATAGGATGTTGGTTAGCACAGAGTGGGAGCTC
TAGAAAGATTGTTGACCAATCATCTTATTGACTAGACCATCTTTCTAGAGTATAACTATTTTGGACACCTCAAAGATGAAGTCAGATAAG
CTGGCAGTGACCTGATTAACGTTGTGGTAAGCAGATGCCACTGTGGCTGGGAAGTACCAAATCTTCTGTTGAGTGATTCAGTCTTCCTGA
CTAGATTTGCCTTCTAGTGGGTGTATTAATAAGCGTTAGTTGATATGAATTAAATGTTGCAACTTTCTATGGGTAATAAGAGGATACCTT
TATAGTTTCATGATGTGGAGACCAAGATACATAAGAAAGCAAGAATGAGTCTCCGGGTGTTCCCTCTGATCAGCAAACATGAATTCATAA
TTTCATTTACTCTCATTTTTGTAATGCACTCTGAGCAATCCTCCAGGCAGATCCTATTTACTAAGCTTCAGGCTTTTGTCCCATTTTATA
ATGCCCAAACACATGGAGAAAACATTTTGTTGTTTTTAAAAACAGGTATGGGATTTCTGATATAATCAATTTTATTGACTTCTTGGGAGT
TGTAATGATCTGTGACTCACTGCATAATATTGTAGTTTTATAGGGTGGCACATCACCCTGTGTAAAACAACTTTAATGACCTGAGGACTG
ATGAGTACAGGAAGTGAGGTTTATCATGAGTAGCATTTATTAAGCATCTGCTAGAATCAAAGCACTGCATTAGCTACTAAGGTACAAAGT
AAGACACAGTTTAATAAGGAAGACAGGGCATCTACCCAAGTCAACAGTTCAGTGACATCTGTTATTTGAACCACACACCAATGCAACCGA
AGTAAATGCTGAAAGGGTGAGAAGAAGGAATAGATTACTATGCATTTTTGAGAGGATGAAGAAGGCTTCTTGGAGAAGGTTTCTGAAAAG
AGATACGGAATTAAGAGAAATAGAAAAGAGCACTGACGAAGCACTCAGGATGGCTATTCAAGGAATTGGGGATCCACAGCAGCTGTGCAC
AACCATCCCTAATGCCAGAAAAATGGGGTAAGGGTGAAGGGAACTGGGTCTAGAGCTTTGCATGTTTTTTTCTGGTTAACCCTTAGAGTC
ACCCTGAAGGTGTGGATCCCATCTTATAATAAGGTGAGGACACTGAGTCAGGAAACTAACTTGCTAAAATCAAGTCCTCCCAGTCCTCCC
ATCAGGTCCTTCCAGATCTGGAGGAGCCAGGATTTGAACTCACATTTGTCTGACTTCAAAATCCATGCTTTTTCTTGTGTTCCAAATTGC
ACAATGGAGTCACTGCCAGTTCAAGCTCCTATGAAAAGGGATGGATGTGAAAAGTCATTTGTTGATTCCACAGATTTTTAGTAGGTACCA
TGTCTCCTGCCTTTATCACTATCCTACTCCTCTGCTACAACTTCTCTGCTACAGGCACCCACTGCAGTTACTTGATATGAGTTAAATGAA
TCCATCCATCCAAACTTCCATTCATTGAATAAATACTTAGCAATGGCTTCCTTTGTATCAGGCACTATTCTAGGAGCTGGGGCTACAGTG
CAGATGGAAACCAGCAAAGCTCACTGCCCTCATGGAGCTTATATGTAAGTGAATAAATCTCAGGGTGGTTCTCCTGTCATAGGTCCTGGC
TCCTCTGCCAGCTCTTCCAAATGGGTTCAGAGAGGTTTTCTCCTTGTCCTGTTGTGTAACTGATAATCCCATGGTGGACCTCACTTTGCT
ATTCATATGCACTAAGTAGTTTATGGTGTGCTTTGTGGCTGGCAATTGTGACAGATTCTATTCTTCTATTGGTATGTGGTTTCTTTGGGG
CATTTGTTTGGATACTGATGGCATCTTCCGGGGGTCTGAGGCACCTACACAAACCTCAGGTCACTATCACGTGATACTGGAGTTGCCTGT
TAAATTATATTTCTTCTTCCACAAAACTGCAGGTTCCCTGAGGGAAAGGTCTATGTCCTGCTCATTTTTGGATCCCTAATGGCTGGCACA
GTACCTGGTGCATAATATGGTTCAACAAATATTTGTAAAATGAATGAATCAAATAGTCCTTCAAAGCATCTTCAGAATCAAGATTGTCAT
CTAGATTGCACCCGAAGTTTATCTTTCTAGTATTCAGAATATAATCAATCATTGCTTAAATTATTCCATTTCATCATTCTTGAATAAAAG
CTACTAATTTTAAATACTAATATCTGAGATATCTTCGAAAAGAAGATTAGTCGTTGTATGTGTTGCTTATAAATTTTCTCTATGGTGGAA
AATATTCCCAAACCATGTCTAAGCAATGAAAAACCAGTGTTCTGGCAGGAAATAAACTGATGTTTGTTGTGTTTTGTATCTGTCTTCCCG
TTCCAAATCATTTATATATACTTGATGGTCTGTGGGCTTGACTTGCAAGTATTTTCCTGGGAGACATTTTTATTCAAAAGACCTGTATTG
CCTGCCAAACCTTCATTTAAGAGACTCATTATGGATGTCATCTGCATCATTGCAAACTTTTCTGGTCGTCTCTATAAATAGCAAGATAAT
ATTTACAGAGTTTTACATTGGCTCTTGAATTTTAAAATATTCTTATAGACAAACATTAATTGGAATGGGGGGTAAGGAGGTAGGAATGGC
TTACTTGCGGAAATGCAGGCTCATTGTTGTGTCTAGTAGGTGCTAGGTGCATTCACACATCTCTTAAGCTTTAAACAACCTATTGAGCCG
GTTTCCATTTCCTTGATCTATTAGATTTAAAAAAATGAAGCATAAAGGAGTTGGCTCTTGCCCTAAGTCATACTACTGATGGAATGAGAA
TACAAACCAAAAACACTTTATTCAAGTCCAGGAAATATCTGCCTTGAAAAAGAATAACTTAAAAATTAAAAGTGTCCTCTATTTGAACAT
GAAAACAGCTAATAAAGATGTGTTATTTTATTTTATTATTATTAATTTTGTCCTCCCATATTGGCAAAGATAAAGCAATTGACAAAAATG
GAATTCTTGTTCAATACTGGCAGGAGTGAAAATTGGTAGAACCTTTCTAGAAGGCAATTTGGCAACATGTATGAAAACCTAAATGTTGAT
ACACCTTTACCCAGCAGTTTGTTTAGGAATTTATCCTAATGAATAAAAGTTGTCCAAGTCTTCAAACATGAGCCCAAAGGTATATTTCAT
GATGTTTATGATATTAAAACATTGGAAACAACTGAAACATCCTTCAGTAAAAGATGGATTAAATAAATTCCATGCAGTTGTCATTTAAAA
ATATTTAGATATATGTTTATTGCTATGGATATATGTTCCCAAAATATTATTGAATCAAAAAGTAGACTACAGGATATATGTTGAATATGA
GCTCATTTATAACATTGAATATTTTAAGATAATGTATGTTTCATAGAGAGATCTTCACCAAATGTTAAGGATTTTTTTTTCTGGGCTGTG
GTATTTGGGTGATCTTTACATTCTTCAGACTCATGTGTGTTTGAAACTTTTTATAATGAACATATATCATTTTTATTAGAAAAGAATAAA

>In-frame_ENST00000542523_ENST00000261233_TCGA-FD-A6TG_TLK2_chr17_60679541_+_IRAK3_chr12_66620502_length(amino acids)=966AA_start in transcript=25_stop in transcript=2925
MMEELHSLDPRRQELLEARFTGVGVSKGPLNSESSNQSLCSVGSLSDKEVETPEKKQNDQRNRKRKAEPYETSQGKGTPRGHKISDYFER
RVEQPLYGLDGSAAKEATEEQSALPTLMSVMLAKPRLDTEQLAQRGAGLCFTFVSAQQNSPSSTGSGNTEHSCSSQKQISIQHRQTQSDL
TIEKISALENSKNSDLEKKEGRIDDLLRANCDLRRQIDEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFTTV
RHGASFTEQWTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKPPAMGQAPPATNEQKQRKSKTNGAENETLTLAEYHEQEEIFKLRLG
HLKKEEAEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKK
ENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLK
PGNILLVNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWFHHPNILELAAYFTETEKFCLIYPYMRNGTLFDRLQCVGDTA
PLPWHIRIGILIGISKAIHYLHNVQPCSVICGSISSANILLDDQFQPKLTDFAMAHFRSHLEHQSCTINMTSSSSKHLWYMPEEYIRQGK
LSIKTDVYSFGIVIMEVLTGCRVVLDDPKHIQLRDLLRELMEKRGLDSCLSFLDKKVPPCPRNFSAKLFCLAGRCAATRAKLRPSMDEVL
NTLESTQASLYFAEDPPTSLKSFRCPSPLFLENVPSIPVEDDESQNNNLLPSDEGLRIDRMTQKTPFECSQSEVMFLSLDKKPESKRNEE

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Fusion Gene PPI Analysis for TLK2-IRAK3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TLK2-IRAK3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
TgeneIRAK3Q9Y616DB12010FostamatinibInhibitorSmall moleculeApproved|Investigational

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Related Diseases for TLK2-IRAK3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneTLK2C4748003MENTAL RETARDATION, AUTOSOMAL DOMINANT 572GENOMICS_ENGLAND;UNIPROT
HgeneTLK2C3714756Intellectual Disability1GENOMICS_ENGLAND
TgeneIRAK3C0035126Reperfusion Injury1CTD_human