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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TMEM30A-SMAP1 (FusionGDB2 ID:91431)

Fusion Gene Summary for TMEM30A-SMAP1

check button Fusion gene summary
Fusion gene informationFusion gene name: TMEM30A-SMAP1
Fusion gene ID: 91431
HgeneTgene
Gene symbol

TMEM30A

SMAP1

Gene ID

55754

60682

Gene nametransmembrane protein 30Asmall ArfGAP 1
SynonymsC6orf67|CDC50ASMAP-1
Cytomap

6q14.1

6q13

Type of geneprotein-codingprotein-coding
Descriptioncell cycle control protein 50AP4-ATPase flippase complex beta subunit TMEM30Astromal membrane-associated protein 1stromal membrane-associated GTPase-activating protein 1
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000230461, ENST00000370050, 
ENST00000475111, 		ENST00000316999, 
ENST00000370452, ENST00000370455, 
ENST00000422334, 
Fusion gene scores* DoF score8 X 7 X 6=3369 X 7 X 6=378
# samples 109
** MAII scorelog2(10/336*10)=-1.74846123300404
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/378*10)=-2.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TMEM30A [Title/Abstract] AND SMAP1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTMEM30A(75994118)-SMAP1(71546644), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneTMEM30A

GO:0006855

drug transmembrane transport

20510206

HgeneTMEM30A

GO:0015917

aminophospholipid transport

20510206

HgeneTMEM30A

GO:0045332

phospholipid translocation

20510206

HgeneTMEM30A

GO:0070863

positive regulation of protein exit from endoplasmic reticulum

21914794


check buttonFusion gene breakpoints across TMEM30A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across SMAP1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AR-A0U4-01ATMEM30Achr6

75994118

-SMAP1chr6

71546644

+


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Fusion Gene ORF analysis for TMEM30A-SMAP1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000230461ENST00000316999TMEM30Achr6

75994118

-SMAP1chr6

71546644

+
In-frameENST00000230461ENST00000370452TMEM30Achr6

75994118

-SMAP1chr6

71546644

+
In-frameENST00000230461ENST00000370455TMEM30Achr6

75994118

-SMAP1chr6

71546644

+
5CDS-intronENST00000230461ENST00000422334TMEM30Achr6

75994118

-SMAP1chr6

71546644

+
intron-3CDSENST00000370050ENST00000316999TMEM30Achr6

75994118

-SMAP1chr6

71546644

+
intron-3CDSENST00000370050ENST00000370452TMEM30Achr6

75994118

-SMAP1chr6

71546644

+
intron-3CDSENST00000370050ENST00000370455TMEM30Achr6

75994118

-SMAP1chr6

71546644

+
intron-intronENST00000370050ENST00000422334TMEM30Achr6

75994118

-SMAP1chr6

71546644

+
In-frameENST00000475111ENST00000316999TMEM30Achr6

75994118

-SMAP1chr6

71546644

+
In-frameENST00000475111ENST00000370452TMEM30Achr6

75994118

-SMAP1chr6

71546644

+
In-frameENST00000475111ENST00000370455TMEM30Achr6

75994118

-SMAP1chr6

71546644

+
5CDS-intronENST00000475111ENST00000422334TMEM30Achr6

75994118

-SMAP1chr6

71546644

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000230461TMEM30Achr675994118-ENST00000316999SMAP1chr671546644+2227567151394459
ENST00000230461TMEM30Achr675994118-ENST00000370452SMAP1chr671546644+2315567151382455
ENST00000230461TMEM30Achr675994118-ENST00000370455SMAP1chr671546644+3076567151394459
ENST00000475111TMEM30Achr675994118-ENST00000316999SMAP1chr671546644+22075471361374412
ENST00000475111TMEM30Achr675994118-ENST00000370452SMAP1chr671546644+22955471361362408
ENST00000475111TMEM30Achr675994118-ENST00000370455SMAP1chr671546644+30565471361374412

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000230461ENST00000316999TMEM30Achr675994118-SMAP1chr671546644+0.044414740.95558524
ENST00000230461ENST00000370452TMEM30Achr675994118-SMAP1chr671546644+0.027471260.97252876
ENST00000230461ENST00000370455TMEM30Achr675994118-SMAP1chr671546644+0.0233326160.9766674
ENST00000475111ENST00000316999TMEM30Achr675994118-SMAP1chr671546644+0.0012574630.9987425
ENST00000475111ENST00000370452TMEM30Achr675994118-SMAP1chr671546644+0.0009758080.99902415
ENST00000475111ENST00000370455TMEM30Achr675994118-SMAP1chr671546644+0.0005446090.9994554

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Fusion Genomic Features for TMEM30A-SMAP1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
TMEM30Achr675994117-SMAP1chr671546643+0.0001176780.99988234
TMEM30Achr675994117-SMAP1chr671546643+0.0001176780.99988234

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TMEM30A-SMAP1


check button Go to

FGviewer for the breakpoints of chr6:75994118-chr6:71546644

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTMEM30Achr6:75994118chr6:71546644ENST00000230461-172_4979.0362.0Topological domainCytoplasmic
HgeneTMEM30Achr6:75994118chr6:71546644ENST00000475111-162_4979.0326.0Topological domainCytoplasmic
HgeneTMEM30Achr6:75994118chr6:71546644ENST00000230461-1750_7079.0362.0TransmembraneHelical
HgeneTMEM30Achr6:75994118chr6:71546644ENST00000475111-1650_7079.0326.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTMEM30Achr6:75994118chr6:71546644ENST00000230461-17347_36179.0362.0Topological domainCytoplasmic
HgeneTMEM30Achr6:75994118chr6:71546644ENST00000230461-1771_32579.0362.0Topological domainExoplasmic loop
HgeneTMEM30Achr6:75994118chr6:71546644ENST00000370050-172_490243.0Topological domainCytoplasmic
HgeneTMEM30Achr6:75994118chr6:71546644ENST00000370050-17347_3610243.0Topological domainCytoplasmic
HgeneTMEM30Achr6:75994118chr6:71546644ENST00000370050-1771_3250243.0Topological domainExoplasmic loop
HgeneTMEM30Achr6:75994118chr6:71546644ENST00000475111-16347_36179.0326.0Topological domainCytoplasmic
HgeneTMEM30Achr6:75994118chr6:71546644ENST00000475111-1671_32579.0326.0Topological domainExoplasmic loop
HgeneTMEM30Achr6:75994118chr6:71546644ENST00000230461-17326_34679.0362.0TransmembraneHelical
HgeneTMEM30Achr6:75994118chr6:71546644ENST00000370050-17326_3460243.0TransmembraneHelical
HgeneTMEM30Achr6:75994118chr6:71546644ENST00000370050-1750_700243.0TransmembraneHelical
HgeneTMEM30Achr6:75994118chr6:71546644ENST00000475111-16326_34679.0326.0TransmembraneHelical
TgeneSMAP1chr6:75994118chr6:71546644ENST0000031699941018_136165.0441.0DomainArf-GAP
TgeneSMAP1chr6:75994118chr6:71546644ENST0000037045241118_136165.0437.0DomainArf-GAP
TgeneSMAP1chr6:75994118chr6:71546644ENST0000037045551118_136192.0468.0DomainArf-GAP
TgeneSMAP1chr6:75994118chr6:71546644ENST0000031699941033_56165.0441.0Zinc fingerC4-type
TgeneSMAP1chr6:75994118chr6:71546644ENST0000037045241133_56165.0437.0Zinc fingerC4-type
TgeneSMAP1chr6:75994118chr6:71546644ENST0000037045551133_56192.0468.0Zinc fingerC4-type


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Fusion Gene Sequence for TMEM30A-SMAP1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000230461_ENST00000316999_TCGA-AR-A0U4-01A_TMEM30A_chr6_75994118_-_SMAP1_chr6_71546644_length(transcript)=2227nt_BP=567nt
CCCGTCACAGGACAGATGATCAGGGTGCGTCCGCCTTTTCGTTCCCGCTTCTATCCTCCTCCCCTTTCCCCTCCCCATGTCCCTCCTTCT
TCTCCCTCCTCCCTCTCTCCCTCCCTCTGGCGTCTCCAGCCGACTTTCGCTTCCCGTCAGCAGCCTTTGGCGGAAGAGTGTCCCGCCTCT
TCCGCTCTACAGCGGAGGTGGCTGTGGCGGTGGCGCTGGTGGCTGCGGCGGCGGCGGCGGCAGCGGCGCTCGAGCGGTTCCTGTCAGGGT
CAGCCGGCGGGCCCCCTGGGTGGTCCACCTGCAAATCGCGGAGCGGCGCCCCAGGGATCGATGGCGATGAACTATAACGCGAAGGATGAA
GTGGACGGTGGGCCCCCGTGTGCTCCGGGGGGCACCGCGAAGACTCGGAGACCGGATAACACGGCCTTCAAACAGCAACGGCTGCCAGCT
TGGCAGCCCATCCTTACGGCTGGCACGGTGCTACCTATTTTCTTCATCATCGGTCTCATCTTCATTCCCATCGGCATTGGCATTTTTGTC
ACCTCCAACAACATCCGCGAGATCGAGCTGCAGAAGAAAGATCAGCAACTGGAGCCTAAAAAAAGTACCAGCCCTAAAAAAGCTGCGGAG
CCCACTGTGGATCTTTTAGGACTTGATGGCCCTGCTGTGGCACCAGTGACCAACGGGAACACAACGGTGCCACCCCTGAACGATGATCTG
GACATCTTTGGACCGATGATTTCTAATCCCTTACCTGCAACTGTCATGCCCCCAGCTCAGGGGACACCCTCTGCACCAGCAGCTGCAACC
CTGTCTACAGTAACATCTGGGGATCTAGATTTATTCACTGAGCAAACTACAAAATCAGAAGAAGTGGCAAAGAAACAACTTTCCAAAGAC
TCCATCTTATCTCTGTATGGCACAGGAACCATTCAACAGCAAAGTACTCCTGGTGTATTTATGGGACCCACAAATATACCATTTACCTCA
CAAGCACCAGCTGCATTTCAGGGCTTTCCATCGATGGGCGTGCCTGTGCCTGCAGCTCCTGGCCTTATAGGAAATGTGATGGGACAGAGT
CCAAGCATGATGGTGGGCATGCCCATGCCCAATGGGTTTATGGGAAATGCACAAACTGGTGTGATGCCACTTCCTCAGAACGTTGTTGGC
CCCCAAGGAGGAATGGTGGGACAAATGGGTGCACCCCAGAGTAAGTTTGGCCTGCCGCAAGCTCAGCAGCCCCAGTGGAGCCTCTCACAG
ATGAATCAGCAGATGGCTGGCATGAGTATCAGTAGTGCAACCCCTACTGCAGGTTTTGGCCAGCCCTCCAGCACAACAGCAGGATGGTCT
GGAAGCTCATCAGGTCAGACTCTCAGCACACAACTGTGGAAATGAAAACTGCAATACAAGTTTCATCCAGAACTACCACCTGACATTCCT
TGCTGAAACGCATCTAGTTCCCCTGTTTATTCATATGCATATTTTTTTTCTTTTTACCCATTTGTTCATATTAAGAATGATCTGATTGAC
CGTGTTGGTCTGTACTGATTCAATTTGATGTGGTGAAAAGCAGGTTGATAAATCATTTTATGTCAAGGGCAGCTTTGCTCATATTTCCCA
TGATTTCATGTACTGCATTATTTGAGAAGCTGCTCAACTTGCAAAATCAGTTTTCCTCTCAATAAAATTATAGCTCTAATGTTTGCATAT
AAGGGAAGTAGTTATCATGTTAGTAATACCTCTAATAGTATAAACCCCACCCCAAAATTAGCCAGTAATCCTGTAGGAAGGTACTGTATG
ATCAAATGTTTAATCATATAAATAGAATGTAAATGTCTCACTGAGCACTGTTTTCTAGTGTATCAAAATGCTCTTATTTCATCATTCACT
TCACTGTGCTGTTGTTATGATGTGCTTAACAGGGAACGTGATTAGTGAAAGGAAGATAAACGTGGATGTTACTCCAAAACTTCGTTTAAT
GAATGCTTAAAGAATTCAAATTTTATCTGCCTCTCTTGTAATTTGGATCTCTTCTTAATGTACATAGTGCTAACATGAAGACCTTTTTCT
GCACTATATGCAAACAGGGTAACTAACTAAAACAAAGCCACTTTCAATCTTCAATCCTTGAAGGTATATCTAGGTTTATGACAGTAATTG

>In-frame_ENST00000230461_ENST00000316999_TCGA-AR-A0U4-01A_TMEM30A_chr6_75994118_-_SMAP1_chr6_71546644_length(amino acids)=459AA_start in transcript=15_stop in transcript=1394
MIRVRPPFRSRFYPPPLSPPHVPPSSPSSLSPSLWRLQPTFASRQQPLAEECPASSALQRRWLWRWRWWLRRRRRQRRSSGSCQGQPAGP
LGGPPANRGAAPQGSMAMNYNAKDEVDGGPPCAPGGTAKTRRPDNTAFKQQRLPAWQPILTAGTVLPIFFIIGLIFIPIGIGIFVTSNNI
REIELQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAVAPVTNGNTTVPPLNDDLDIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVT
SGDLDLFTEQTTKSEEVAKKQLSKDSILSLYGTGTIQQQSTPGVFMGPTNIPFTSQAPAAFQGFPSMGVPVPAAPGLIGNVMGQSPSMMV
GMPMPNGFMGNAQTGVMPLPQNVVGPQGGMVGQMGAPQSKFGLPQAQQPQWSLSQMNQQMAGMSISSATPTAGFGQPSSTTAGWSGSSSG

--------------------------------------------------------------
>In-frame_ENST00000230461_ENST00000370452_TCGA-AR-A0U4-01A_TMEM30A_chr6_75994118_-_SMAP1_chr6_71546644_length(transcript)=2315nt_BP=567nt
CCCGTCACAGGACAGATGATCAGGGTGCGTCCGCCTTTTCGTTCCCGCTTCTATCCTCCTCCCCTTTCCCCTCCCCATGTCCCTCCTTCT
TCTCCCTCCTCCCTCTCTCCCTCCCTCTGGCGTCTCCAGCCGACTTTCGCTTCCCGTCAGCAGCCTTTGGCGGAAGAGTGTCCCGCCTCT
TCCGCTCTACAGCGGAGGTGGCTGTGGCGGTGGCGCTGGTGGCTGCGGCGGCGGCGGCGGCAGCGGCGCTCGAGCGGTTCCTGTCAGGGT
CAGCCGGCGGGCCCCCTGGGTGGTCCACCTGCAAATCGCGGAGCGGCGCCCCAGGGATCGATGGCGATGAACTATAACGCGAAGGATGAA
GTGGACGGTGGGCCCCCGTGTGCTCCGGGGGGCACCGCGAAGACTCGGAGACCGGATAACACGGCCTTCAAACAGCAACGGCTGCCAGCT
TGGCAGCCCATCCTTACGGCTGGCACGGTGCTACCTATTTTCTTCATCATCGGTCTCATCTTCATTCCCATCGGCATTGGCATTTTTGTC
ACCTCCAACAACATCCGCGAGATCGAGCTGCAGAAGAAAGATCAGCAACTGGAGCCTAAAAAAAGTACCAGCCCTAAAAAAGCTGCGGAG
CCCACTGTGGATCTTTTAGGACTTGATGGCCCTGCTGTGGCACCAGTGACCAACGGGAACACAACGGTGCCACCCCTGAACGATGATCTG
GACATCTTTGGACCGATGATTTCTAATCCCTTACCTGCAACTGTCATGCCCCCAGCTCAGGGGACACCCTCTGCACCAGCAGCTGCAACC
CTGTCTACAGTAACATCTGGGGATCTAGATTTATTCACTGAGCAAACTACAAAATCAGAAGAAGTGGCAAAGAAACAACTTTCCAAAGAC
TCCATCTTATCTCTGTATGGCACAGGAACCATTCAACAGCAAAGTACTCCTGGTGTATTTATGGGACCCACAAATATACCATTTACCTCA
CAAGCACCAGCTGCATTTCAGGGCTTTCCATCGATGGGCGTGCCTGTGCCTGCAGCTCCTGGCCTTATAGGAAATGTGATGGGACAGAGT
CCAAGCATGATGGTGGGCATGCCCATGCCCAATGGGTTTATGGGAAATGCACAAACTGGTGTGATGCCACTTCCTCAGAACGTTGTTGGC
CCCCAAGGAGGAATGGTGGGACAAATGGGTGCACCCCAGAGTAAGTTTGGCCTGCCGCAAGCTCAGCAGCCCCAGTGGAGCCTCTCACAG
ATAATGCAGAAGGGTGATGCTGTTCTCCAGCACTCCATCAGTGCAATCTACTGGCCAATGACAAGGTGGTTAAAATGTCCTTTAGTAGAT
GAATCAGCAGATGGCTGGCATGAGTATCAGTAGTGCAACCCCTACTGCAGGTTTTGGCCAGCCCTCCAGCACAACAGCAGGATGGTCTGG
AAGCTCATCAGGTCAGACTCTCAGCACACAACTGTGGAAATGAAAACTGCAATACAAGTTTCATCCAGAACTACCACCTGACATTCCTTG
CTGAAACGCATCTAGTTCCCCTGTTTATTCATATGCATATTTTTTTTCTTTTTACCCATTTGTTCATATTAAGAATGATCTGATTGACCG
TGTTGGTCTGTACTGATTCAATTTGATGTGGTGAAAAGCAGGTTGATAAATCATTTTATGTCAAGGGCAGCTTTGCTCATATTTCCCATG
ATTTCATGTACTGCATTATTTGAGAAGCTGCTCAACTTGCAAAATCAGTTTTCCTCTCAATAAAATTATAGCTCTAATGTTTGCATATAA
GGGAAGTAGTTATCATGTTAGTAATACCTCTAATAGTATAAACCCCACCCCAAAATTAGCCAGTAATCCTGTAGGAAGGTACTGTATGAT
CAAATGTTTAATCATATAAATAGAATGTAAATGTCTCACTGAGCACTGTTTTCTAGTGTATCAAAATGCTCTTATTTCATCATTCACTTC
ACTGTGCTGTTGTTATGATGTGCTTAACAGGGAACGTGATTAGTGAAAGGAAGATAAACGTGGATGTTACTCCAAAACTTCGTTTAATGA
ATGCTTAAAGAATTCAAATTTTATCTGCCTCTCTTGTAATTTGGATCTCTTCTTAATGTACATAGTGCTAACATGAAGACCTTTTTCTGC
ACTATATGCAAACAGGGTAACTAACTAAAACAAAGCCACTTTCAATCTTCAATCCTTGAAGGTATATCTAGGTTTATGACAGTAATTGTG

>In-frame_ENST00000230461_ENST00000370452_TCGA-AR-A0U4-01A_TMEM30A_chr6_75994118_-_SMAP1_chr6_71546644_length(amino acids)=455AA_start in transcript=15_stop in transcript=1382
MIRVRPPFRSRFYPPPLSPPHVPPSSPSSLSPSLWRLQPTFASRQQPLAEECPASSALQRRWLWRWRWWLRRRRRQRRSSGSCQGQPAGP
LGGPPANRGAAPQGSMAMNYNAKDEVDGGPPCAPGGTAKTRRPDNTAFKQQRLPAWQPILTAGTVLPIFFIIGLIFIPIGIGIFVTSNNI
REIELQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAVAPVTNGNTTVPPLNDDLDIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVT
SGDLDLFTEQTTKSEEVAKKQLSKDSILSLYGTGTIQQQSTPGVFMGPTNIPFTSQAPAAFQGFPSMGVPVPAAPGLIGNVMGQSPSMMV
GMPMPNGFMGNAQTGVMPLPQNVVGPQGGMVGQMGAPQSKFGLPQAQQPQWSLSQIMQKGDAVLQHSISAIYWPMTRWLKCPLVDESADG

--------------------------------------------------------------
>In-frame_ENST00000230461_ENST00000370455_TCGA-AR-A0U4-01A_TMEM30A_chr6_75994118_-_SMAP1_chr6_71546644_length(transcript)=3076nt_BP=567nt
CCCGTCACAGGACAGATGATCAGGGTGCGTCCGCCTTTTCGTTCCCGCTTCTATCCTCCTCCCCTTTCCCCTCCCCATGTCCCTCCTTCT
TCTCCCTCCTCCCTCTCTCCCTCCCTCTGGCGTCTCCAGCCGACTTTCGCTTCCCGTCAGCAGCCTTTGGCGGAAGAGTGTCCCGCCTCT
TCCGCTCTACAGCGGAGGTGGCTGTGGCGGTGGCGCTGGTGGCTGCGGCGGCGGCGGCGGCAGCGGCGCTCGAGCGGTTCCTGTCAGGGT
CAGCCGGCGGGCCCCCTGGGTGGTCCACCTGCAAATCGCGGAGCGGCGCCCCAGGGATCGATGGCGATGAACTATAACGCGAAGGATGAA
GTGGACGGTGGGCCCCCGTGTGCTCCGGGGGGCACCGCGAAGACTCGGAGACCGGATAACACGGCCTTCAAACAGCAACGGCTGCCAGCT
TGGCAGCCCATCCTTACGGCTGGCACGGTGCTACCTATTTTCTTCATCATCGGTCTCATCTTCATTCCCATCGGCATTGGCATTTTTGTC
ACCTCCAACAACATCCGCGAGATCGAGCTGCAGAAGAAAGATCAGCAACTGGAGCCTAAAAAAAGTACCAGCCCTAAAAAAGCTGCGGAG
CCCACTGTGGATCTTTTAGGACTTGATGGCCCTGCTGTGGCACCAGTGACCAACGGGAACACAACGGTGCCACCCCTGAACGATGATCTG
GACATCTTTGGACCGATGATTTCTAATCCCTTACCTGCAACTGTCATGCCCCCAGCTCAGGGGACACCCTCTGCACCAGCAGCTGCAACC
CTGTCTACAGTAACATCTGGGGATCTAGATTTATTCACTGAGCAAACTACAAAATCAGAAGAAGTGGCAAAGAAACAACTTTCCAAAGAC
TCCATCTTATCTCTGTATGGCACAGGAACCATTCAACAGCAAAGTACTCCTGGTGTATTTATGGGACCCACAAATATACCATTTACCTCA
CAAGCACCAGCTGCATTTCAGGGCTTTCCATCGATGGGCGTGCCTGTGCCTGCAGCTCCTGGCCTTATAGGAAATGTGATGGGACAGAGT
CCAAGCATGATGGTGGGCATGCCCATGCCCAATGGGTTTATGGGAAATGCACAAACTGGTGTGATGCCACTTCCTCAGAACGTTGTTGGC
CCCCAAGGAGGAATGGTGGGACAAATGGGTGCACCCCAGAGTAAGTTTGGCCTGCCGCAAGCTCAGCAGCCCCAGTGGAGCCTCTCACAG
ATGAATCAGCAGATGGCTGGCATGAGTATCAGTAGTGCAACCCCTACTGCAGGTTTTGGCCAGCCCTCCAGCACAACAGCAGGATGGTCT
GGAAGCTCATCAGGTCAGACTCTCAGCACACAACTGTGGAAATGAAAACTGCAATACAAGTTTCATCCAGAACTACCACCTGACATTCCT
TGCTGAAACGCATCTAGTTCCCCTGTTTATTCATATGCATATTTTTTTTCTTTTTACCCATTTGTTCATATTAAGAATGATCTGATTGAC
CGTGTTGGTCTGTACTGATTCAATTTGATGTGGTGAAAAGCAGGTTGATAAATCATTTTATGTCAAGGGCAGCTTTGCTCATATTTCCCA
TGATTTCATGTACTGCATTATTTGAGAAGCTGCTCAACTTGCAAAATCAGTTTTCCTCTCAATAAAATTATAGCTCTAATGTTTGCATAT
AAGGGAAGTAGTTATCATGTTAGTAATACCTCTAATAGTATAAACCCCACCCCAAAATTAGCCAGTAATCCTGTAGGAAGGTACTGTATG
ATCAAATGTTTAATCATATAAATAGAATGTAAATGTCTCACTGAGCACTGTTTTCTAGTGTATCAAAATGCTCTTATTTCATCATTCACT
TCACTGTGCTGTTGTTATGATGTGCTTAACAGGGAACGTGATTAGTGAAAGGAAGATAAACGTGGATGTTACTCCAAAACTTCGTTTAAT
GAATGCTTAAAGAATTCAAATTTTATCTGCCTCTCTTGTAATTTGGATCTCTTCTTAATGTACATAGTGCTAACATGAAGACCTTTTTCT
GCACTATATGCAAACAGGGTAACTAACTAAAACAAAGCCACTTTCAATCTTCAATCCTTGAAGGTATATCTAGGTTTATGACAGTAATTG
TGTTTACATTTTATGGTGCCTAGTATTGACAAAATGTTATTTCCCTACATTAAACATGACTCCATAGACCTTTTCATTTGTGGGTTTTTA
TTTCCTATGATGTATACTGCCACTAACCTTCCAAAAATTACTTAGTATTGCAAAGTCAGGAATCATCAGGAACGTTTAGCTGACAAAATA
CTTGTCTGTTTTAAAAACCTGTTCAAGTCTACCAACCTGTTCAAGTCTACCAATTATAAGGGCAAATTGGAGAAAAAGAAAAAATATATA
CTCAAGAGTGGTATCTTGCAGTATCGGCACTGTACAAAAAAATCTTCCAATTTAGTTGTTGTAGAGAAAACATGCAGAACAAATGAAGAC
AAAACATACATTTTGTACCAACCATCCAATTAGCTTATGTTAACTGACAAGCTCCATTTAAACAGATGTCCATCAGATGACAAGAAAGGC
TGCTGTACTGAAGTAAAACAAACAATACCTGAATGCTCTGTAGCCTAAACTCCAAACATCCTCTTCCATATGGATCCACTGGCTGGACAA
ACTGCACCAGTTGCTGCTTCAATTTATACCTCAATTTTCACTGTGTCCAGGTGGTACTTTGGCTCGTTGGCTAGATTAACCTTCTCTGTC
CGAGTGTGCCACACGAGAACCTGAAGGGGAAGGAAATAGCTTGGGTAGCGCACTCTTCATGGTGACACTCGAGGTCGGGCAGCACAAGTG
TAATGAATACCTTAGTGCAGTTATTTGCTTTCGGTTCCAGTTCTTCGACTGTTGTTATCTGTTTGAGAAAGTCAGATTCTTGCATCCCTG
GCTGGGATCCACGACGCTTAAATACAGCTTTTGGATTGGACAAAATGACTTGAAGACTTACAGCAAATCCTTTGTGAAAAATAAAAAAAA

>In-frame_ENST00000230461_ENST00000370455_TCGA-AR-A0U4-01A_TMEM30A_chr6_75994118_-_SMAP1_chr6_71546644_length(amino acids)=459AA_start in transcript=15_stop in transcript=1394
MIRVRPPFRSRFYPPPLSPPHVPPSSPSSLSPSLWRLQPTFASRQQPLAEECPASSALQRRWLWRWRWWLRRRRRQRRSSGSCQGQPAGP
LGGPPANRGAAPQGSMAMNYNAKDEVDGGPPCAPGGTAKTRRPDNTAFKQQRLPAWQPILTAGTVLPIFFIIGLIFIPIGIGIFVTSNNI
REIELQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAVAPVTNGNTTVPPLNDDLDIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVT
SGDLDLFTEQTTKSEEVAKKQLSKDSILSLYGTGTIQQQSTPGVFMGPTNIPFTSQAPAAFQGFPSMGVPVPAAPGLIGNVMGQSPSMMV
GMPMPNGFMGNAQTGVMPLPQNVVGPQGGMVGQMGAPQSKFGLPQAQQPQWSLSQMNQQMAGMSISSATPTAGFGQPSSTTAGWSGSSSG

--------------------------------------------------------------
>In-frame_ENST00000475111_ENST00000316999_TCGA-AR-A0U4-01A_TMEM30A_chr6_75994118_-_SMAP1_chr6_71546644_length(transcript)=2207nt_BP=547nt
CAGGGTGCGTCCGCCTTTTCGTTCCCGCTTCTATCCTCCTCCCCTTTCCCCTCCCCATGTCCCTCCTTCTTCTCCCTCCTCCCTCTCTCC
CTCCCTCTGGCGTCTCCAGCCGACTTTCGCTTCCCGTCAGCAGCCTTTGGCGGAAGAGTGTCCCGCCTCTTCCGCTCTACAGCGGAGGTG
GCTGTGGCGGTGGCGCTGGTGGCTGCGGCGGCGGCGGCGGCAGCGGCGCTCGAGCGGTTCCTGTCAGGGTCAGCCGGCGGGCCCCCTGGG
TGGTCCACCTGCAAATCGCGGAGCGGCGCCCCAGGGATCGATGGCGATGAACTATAACGCGAAGGATGAAGTGGACGGTGGGCCCCCGTG
TGCTCCGGGGGGCACCGCGAAGACTCGGAGACCGGATAACACGGCCTTCAAACAGCAACGGCTGCCAGCTTGGCAGCCCATCCTTACGGC
TGGCACGGTGCTACCTATTTTCTTCATCATCGGTCTCATCTTCATTCCCATCGGCATTGGCATTTTTGTCACCTCCAACAACATCCGCGA
GATCGAGCTGCAGAAGAAAGATCAGCAACTGGAGCCTAAAAAAAGTACCAGCCCTAAAAAAGCTGCGGAGCCCACTGTGGATCTTTTAGG
ACTTGATGGCCCTGCTGTGGCACCAGTGACCAACGGGAACACAACGGTGCCACCCCTGAACGATGATCTGGACATCTTTGGACCGATGAT
TTCTAATCCCTTACCTGCAACTGTCATGCCCCCAGCTCAGGGGACACCCTCTGCACCAGCAGCTGCAACCCTGTCTACAGTAACATCTGG
GGATCTAGATTTATTCACTGAGCAAACTACAAAATCAGAAGAAGTGGCAAAGAAACAACTTTCCAAAGACTCCATCTTATCTCTGTATGG
CACAGGAACCATTCAACAGCAAAGTACTCCTGGTGTATTTATGGGACCCACAAATATACCATTTACCTCACAAGCACCAGCTGCATTTCA
GGGCTTTCCATCGATGGGCGTGCCTGTGCCTGCAGCTCCTGGCCTTATAGGAAATGTGATGGGACAGAGTCCAAGCATGATGGTGGGCAT
GCCCATGCCCAATGGGTTTATGGGAAATGCACAAACTGGTGTGATGCCACTTCCTCAGAACGTTGTTGGCCCCCAAGGAGGAATGGTGGG
ACAAATGGGTGCACCCCAGAGTAAGTTTGGCCTGCCGCAAGCTCAGCAGCCCCAGTGGAGCCTCTCACAGATGAATCAGCAGATGGCTGG
CATGAGTATCAGTAGTGCAACCCCTACTGCAGGTTTTGGCCAGCCCTCCAGCACAACAGCAGGATGGTCTGGAAGCTCATCAGGTCAGAC
TCTCAGCACACAACTGTGGAAATGAAAACTGCAATACAAGTTTCATCCAGAACTACCACCTGACATTCCTTGCTGAAACGCATCTAGTTC
CCCTGTTTATTCATATGCATATTTTTTTTCTTTTTACCCATTTGTTCATATTAAGAATGATCTGATTGACCGTGTTGGTCTGTACTGATT
CAATTTGATGTGGTGAAAAGCAGGTTGATAAATCATTTTATGTCAAGGGCAGCTTTGCTCATATTTCCCATGATTTCATGTACTGCATTA
TTTGAGAAGCTGCTCAACTTGCAAAATCAGTTTTCCTCTCAATAAAATTATAGCTCTAATGTTTGCATATAAGGGAAGTAGTTATCATGT
TAGTAATACCTCTAATAGTATAAACCCCACCCCAAAATTAGCCAGTAATCCTGTAGGAAGGTACTGTATGATCAAATGTTTAATCATATA
AATAGAATGTAAATGTCTCACTGAGCACTGTTTTCTAGTGTATCAAAATGCTCTTATTTCATCATTCACTTCACTGTGCTGTTGTTATGA
TGTGCTTAACAGGGAACGTGATTAGTGAAAGGAAGATAAACGTGGATGTTACTCCAAAACTTCGTTTAATGAATGCTTAAAGAATTCAAA
TTTTATCTGCCTCTCTTGTAATTTGGATCTCTTCTTAATGTACATAGTGCTAACATGAAGACCTTTTTCTGCACTATATGCAAACAGGGT
AACTAACTAAAACAAAGCCACTTTCAATCTTCAATCCTTGAAGGTATATCTAGGTTTATGACAGTAATTGTGTTTACATTTTATGGTGCC

>In-frame_ENST00000475111_ENST00000316999_TCGA-AR-A0U4-01A_TMEM30A_chr6_75994118_-_SMAP1_chr6_71546644_length(amino acids)=412AA_start in transcript=136_stop in transcript=1374
MAEECPASSALQRRWLWRWRWWLRRRRRQRRSSGSCQGQPAGPLGGPPANRGAAPQGSMAMNYNAKDEVDGGPPCAPGGTAKTRRPDNTA
FKQQRLPAWQPILTAGTVLPIFFIIGLIFIPIGIGIFVTSNNIREIELQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAVAPVTNGNTT
VPPLNDDLDIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQLSKDSILSLYGTGTIQQQSTPGVFMG
PTNIPFTSQAPAAFQGFPSMGVPVPAAPGLIGNVMGQSPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQGGMVGQMGAPQSKFGLPQAQ

--------------------------------------------------------------
>In-frame_ENST00000475111_ENST00000370452_TCGA-AR-A0U4-01A_TMEM30A_chr6_75994118_-_SMAP1_chr6_71546644_length(transcript)=2295nt_BP=547nt
CAGGGTGCGTCCGCCTTTTCGTTCCCGCTTCTATCCTCCTCCCCTTTCCCCTCCCCATGTCCCTCCTTCTTCTCCCTCCTCCCTCTCTCC
CTCCCTCTGGCGTCTCCAGCCGACTTTCGCTTCCCGTCAGCAGCCTTTGGCGGAAGAGTGTCCCGCCTCTTCCGCTCTACAGCGGAGGTG
GCTGTGGCGGTGGCGCTGGTGGCTGCGGCGGCGGCGGCGGCAGCGGCGCTCGAGCGGTTCCTGTCAGGGTCAGCCGGCGGGCCCCCTGGG
TGGTCCACCTGCAAATCGCGGAGCGGCGCCCCAGGGATCGATGGCGATGAACTATAACGCGAAGGATGAAGTGGACGGTGGGCCCCCGTG
TGCTCCGGGGGGCACCGCGAAGACTCGGAGACCGGATAACACGGCCTTCAAACAGCAACGGCTGCCAGCTTGGCAGCCCATCCTTACGGC
TGGCACGGTGCTACCTATTTTCTTCATCATCGGTCTCATCTTCATTCCCATCGGCATTGGCATTTTTGTCACCTCCAACAACATCCGCGA
GATCGAGCTGCAGAAGAAAGATCAGCAACTGGAGCCTAAAAAAAGTACCAGCCCTAAAAAAGCTGCGGAGCCCACTGTGGATCTTTTAGG
ACTTGATGGCCCTGCTGTGGCACCAGTGACCAACGGGAACACAACGGTGCCACCCCTGAACGATGATCTGGACATCTTTGGACCGATGAT
TTCTAATCCCTTACCTGCAACTGTCATGCCCCCAGCTCAGGGGACACCCTCTGCACCAGCAGCTGCAACCCTGTCTACAGTAACATCTGG
GGATCTAGATTTATTCACTGAGCAAACTACAAAATCAGAAGAAGTGGCAAAGAAACAACTTTCCAAAGACTCCATCTTATCTCTGTATGG
CACAGGAACCATTCAACAGCAAAGTACTCCTGGTGTATTTATGGGACCCACAAATATACCATTTACCTCACAAGCACCAGCTGCATTTCA
GGGCTTTCCATCGATGGGCGTGCCTGTGCCTGCAGCTCCTGGCCTTATAGGAAATGTGATGGGACAGAGTCCAAGCATGATGGTGGGCAT
GCCCATGCCCAATGGGTTTATGGGAAATGCACAAACTGGTGTGATGCCACTTCCTCAGAACGTTGTTGGCCCCCAAGGAGGAATGGTGGG
ACAAATGGGTGCACCCCAGAGTAAGTTTGGCCTGCCGCAAGCTCAGCAGCCCCAGTGGAGCCTCTCACAGATAATGCAGAAGGGTGATGC
TGTTCTCCAGCACTCCATCAGTGCAATCTACTGGCCAATGACAAGGTGGTTAAAATGTCCTTTAGTAGATGAATCAGCAGATGGCTGGCA
TGAGTATCAGTAGTGCAACCCCTACTGCAGGTTTTGGCCAGCCCTCCAGCACAACAGCAGGATGGTCTGGAAGCTCATCAGGTCAGACTC
TCAGCACACAACTGTGGAAATGAAAACTGCAATACAAGTTTCATCCAGAACTACCACCTGACATTCCTTGCTGAAACGCATCTAGTTCCC
CTGTTTATTCATATGCATATTTTTTTTCTTTTTACCCATTTGTTCATATTAAGAATGATCTGATTGACCGTGTTGGTCTGTACTGATTCA
ATTTGATGTGGTGAAAAGCAGGTTGATAAATCATTTTATGTCAAGGGCAGCTTTGCTCATATTTCCCATGATTTCATGTACTGCATTATT
TGAGAAGCTGCTCAACTTGCAAAATCAGTTTTCCTCTCAATAAAATTATAGCTCTAATGTTTGCATATAAGGGAAGTAGTTATCATGTTA
GTAATACCTCTAATAGTATAAACCCCACCCCAAAATTAGCCAGTAATCCTGTAGGAAGGTACTGTATGATCAAATGTTTAATCATATAAA
TAGAATGTAAATGTCTCACTGAGCACTGTTTTCTAGTGTATCAAAATGCTCTTATTTCATCATTCACTTCACTGTGCTGTTGTTATGATG
TGCTTAACAGGGAACGTGATTAGTGAAAGGAAGATAAACGTGGATGTTACTCCAAAACTTCGTTTAATGAATGCTTAAAGAATTCAAATT
TTATCTGCCTCTCTTGTAATTTGGATCTCTTCTTAATGTACATAGTGCTAACATGAAGACCTTTTTCTGCACTATATGCAAACAGGGTAA
CTAACTAAAACAAAGCCACTTTCAATCTTCAATCCTTGAAGGTATATCTAGGTTTATGACAGTAATTGTGTTTACATTTTATGGTGCCTA

>In-frame_ENST00000475111_ENST00000370452_TCGA-AR-A0U4-01A_TMEM30A_chr6_75994118_-_SMAP1_chr6_71546644_length(amino acids)=408AA_start in transcript=136_stop in transcript=1362
MAEECPASSALQRRWLWRWRWWLRRRRRQRRSSGSCQGQPAGPLGGPPANRGAAPQGSMAMNYNAKDEVDGGPPCAPGGTAKTRRPDNTA
FKQQRLPAWQPILTAGTVLPIFFIIGLIFIPIGIGIFVTSNNIREIELQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAVAPVTNGNTT
VPPLNDDLDIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQLSKDSILSLYGTGTIQQQSTPGVFMG
PTNIPFTSQAPAAFQGFPSMGVPVPAAPGLIGNVMGQSPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQGGMVGQMGAPQSKFGLPQAQ

--------------------------------------------------------------
>In-frame_ENST00000475111_ENST00000370455_TCGA-AR-A0U4-01A_TMEM30A_chr6_75994118_-_SMAP1_chr6_71546644_length(transcript)=3056nt_BP=547nt
CAGGGTGCGTCCGCCTTTTCGTTCCCGCTTCTATCCTCCTCCCCTTTCCCCTCCCCATGTCCCTCCTTCTTCTCCCTCCTCCCTCTCTCC
CTCCCTCTGGCGTCTCCAGCCGACTTTCGCTTCCCGTCAGCAGCCTTTGGCGGAAGAGTGTCCCGCCTCTTCCGCTCTACAGCGGAGGTG
GCTGTGGCGGTGGCGCTGGTGGCTGCGGCGGCGGCGGCGGCAGCGGCGCTCGAGCGGTTCCTGTCAGGGTCAGCCGGCGGGCCCCCTGGG
TGGTCCACCTGCAAATCGCGGAGCGGCGCCCCAGGGATCGATGGCGATGAACTATAACGCGAAGGATGAAGTGGACGGTGGGCCCCCGTG
TGCTCCGGGGGGCACCGCGAAGACTCGGAGACCGGATAACACGGCCTTCAAACAGCAACGGCTGCCAGCTTGGCAGCCCATCCTTACGGC
TGGCACGGTGCTACCTATTTTCTTCATCATCGGTCTCATCTTCATTCCCATCGGCATTGGCATTTTTGTCACCTCCAACAACATCCGCGA
GATCGAGCTGCAGAAGAAAGATCAGCAACTGGAGCCTAAAAAAAGTACCAGCCCTAAAAAAGCTGCGGAGCCCACTGTGGATCTTTTAGG
ACTTGATGGCCCTGCTGTGGCACCAGTGACCAACGGGAACACAACGGTGCCACCCCTGAACGATGATCTGGACATCTTTGGACCGATGAT
TTCTAATCCCTTACCTGCAACTGTCATGCCCCCAGCTCAGGGGACACCCTCTGCACCAGCAGCTGCAACCCTGTCTACAGTAACATCTGG
GGATCTAGATTTATTCACTGAGCAAACTACAAAATCAGAAGAAGTGGCAAAGAAACAACTTTCCAAAGACTCCATCTTATCTCTGTATGG
CACAGGAACCATTCAACAGCAAAGTACTCCTGGTGTATTTATGGGACCCACAAATATACCATTTACCTCACAAGCACCAGCTGCATTTCA
GGGCTTTCCATCGATGGGCGTGCCTGTGCCTGCAGCTCCTGGCCTTATAGGAAATGTGATGGGACAGAGTCCAAGCATGATGGTGGGCAT
GCCCATGCCCAATGGGTTTATGGGAAATGCACAAACTGGTGTGATGCCACTTCCTCAGAACGTTGTTGGCCCCCAAGGAGGAATGGTGGG
ACAAATGGGTGCACCCCAGAGTAAGTTTGGCCTGCCGCAAGCTCAGCAGCCCCAGTGGAGCCTCTCACAGATGAATCAGCAGATGGCTGG
CATGAGTATCAGTAGTGCAACCCCTACTGCAGGTTTTGGCCAGCCCTCCAGCACAACAGCAGGATGGTCTGGAAGCTCATCAGGTCAGAC
TCTCAGCACACAACTGTGGAAATGAAAACTGCAATACAAGTTTCATCCAGAACTACCACCTGACATTCCTTGCTGAAACGCATCTAGTTC
CCCTGTTTATTCATATGCATATTTTTTTTCTTTTTACCCATTTGTTCATATTAAGAATGATCTGATTGACCGTGTTGGTCTGTACTGATT
CAATTTGATGTGGTGAAAAGCAGGTTGATAAATCATTTTATGTCAAGGGCAGCTTTGCTCATATTTCCCATGATTTCATGTACTGCATTA
TTTGAGAAGCTGCTCAACTTGCAAAATCAGTTTTCCTCTCAATAAAATTATAGCTCTAATGTTTGCATATAAGGGAAGTAGTTATCATGT
TAGTAATACCTCTAATAGTATAAACCCCACCCCAAAATTAGCCAGTAATCCTGTAGGAAGGTACTGTATGATCAAATGTTTAATCATATA
AATAGAATGTAAATGTCTCACTGAGCACTGTTTTCTAGTGTATCAAAATGCTCTTATTTCATCATTCACTTCACTGTGCTGTTGTTATGA
TGTGCTTAACAGGGAACGTGATTAGTGAAAGGAAGATAAACGTGGATGTTACTCCAAAACTTCGTTTAATGAATGCTTAAAGAATTCAAA
TTTTATCTGCCTCTCTTGTAATTTGGATCTCTTCTTAATGTACATAGTGCTAACATGAAGACCTTTTTCTGCACTATATGCAAACAGGGT
AACTAACTAAAACAAAGCCACTTTCAATCTTCAATCCTTGAAGGTATATCTAGGTTTATGACAGTAATTGTGTTTACATTTTATGGTGCC
TAGTATTGACAAAATGTTATTTCCCTACATTAAACATGACTCCATAGACCTTTTCATTTGTGGGTTTTTATTTCCTATGATGTATACTGC
CACTAACCTTCCAAAAATTACTTAGTATTGCAAAGTCAGGAATCATCAGGAACGTTTAGCTGACAAAATACTTGTCTGTTTTAAAAACCT
GTTCAAGTCTACCAACCTGTTCAAGTCTACCAATTATAAGGGCAAATTGGAGAAAAAGAAAAAATATATACTCAAGAGTGGTATCTTGCA
GTATCGGCACTGTACAAAAAAATCTTCCAATTTAGTTGTTGTAGAGAAAACATGCAGAACAAATGAAGACAAAACATACATTTTGTACCA
ACCATCCAATTAGCTTATGTTAACTGACAAGCTCCATTTAAACAGATGTCCATCAGATGACAAGAAAGGCTGCTGTACTGAAGTAAAACA
AACAATACCTGAATGCTCTGTAGCCTAAACTCCAAACATCCTCTTCCATATGGATCCACTGGCTGGACAAACTGCACCAGTTGCTGCTTC
AATTTATACCTCAATTTTCACTGTGTCCAGGTGGTACTTTGGCTCGTTGGCTAGATTAACCTTCTCTGTCCGAGTGTGCCACACGAGAAC
CTGAAGGGGAAGGAAATAGCTTGGGTAGCGCACTCTTCATGGTGACACTCGAGGTCGGGCAGCACAAGTGTAATGAATACCTTAGTGCAG
TTATTTGCTTTCGGTTCCAGTTCTTCGACTGTTGTTATCTGTTTGAGAAAGTCAGATTCTTGCATCCCTGGCTGGGATCCACGACGCTTA

>In-frame_ENST00000475111_ENST00000370455_TCGA-AR-A0U4-01A_TMEM30A_chr6_75994118_-_SMAP1_chr6_71546644_length(amino acids)=412AA_start in transcript=136_stop in transcript=1374
MAEECPASSALQRRWLWRWRWWLRRRRRQRRSSGSCQGQPAGPLGGPPANRGAAPQGSMAMNYNAKDEVDGGPPCAPGGTAKTRRPDNTA
FKQQRLPAWQPILTAGTVLPIFFIIGLIFIPIGIGIFVTSNNIREIELQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAVAPVTNGNTT
VPPLNDDLDIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQLSKDSILSLYGTGTIQQQSTPGVFMG
PTNIPFTSQAPAAFQGFPSMGVPVPAAPGLIGNVMGQSPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQGGMVGQMGAPQSKFGLPQAQ

--------------------------------------------------------------

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Fusion Gene PPI Analysis for TMEM30A-SMAP1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TMEM30A-SMAP1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TMEM30A-SMAP1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource