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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TMOD3-PICALM (FusionGDB2 ID:91695)

Fusion Gene Summary for TMOD3-PICALM

check button Fusion gene summary
Fusion gene informationFusion gene name: TMOD3-PICALM
Fusion gene ID: 91695
HgeneTgene
Gene symbol

TMOD3

PICALM

Gene ID

29766

8301

Gene nametropomodulin 3phosphatidylinositol binding clathrin assembly protein
SynonymsUTMODCALM|CLTH|LAP
Cytomap

15q21.2

11q14.2

Type of geneprotein-codingprotein-coding
Descriptiontropomodulin-3tropomodulin 3 (ubiquitous)ubiquitous tropomodulinphosphatidylinositol-binding clathrin assembly proteinclathrin assembly lymphoid myeloid leukemia protein
Modification date2020031320200322
UniProtAcc.

Q13492

Ensembl transtripts involved in fusion geneENST00000308580, ENST00000544199, 
ENST00000561136, 		ENST00000532317, 
ENST00000526033, ENST00000393346, 
ENST00000528398, ENST00000356360, 
ENST00000528411, 
Fusion gene scores* DoF score9 X 8 X 6=43235 X 26 X 12=10920
# samples 1044
** MAII scorelog2(10/432*10)=-2.11103131238874
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(44/10920*10)=-4.63332552228256
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TMOD3 [Title/Abstract] AND PICALM [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTMOD3(52194233)-PICALM(85722179), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgenePICALM

GO:0006897

endocytosis

22118466

TgenePICALM

GO:0006898

receptor-mediated endocytosis

10436022

TgenePICALM

GO:0032880

regulation of protein localization

10436022

TgenePICALM

GO:0045893

positive regulation of transcription, DNA-templated

11425879

TgenePICALM

GO:0048261

negative regulation of receptor-mediated endocytosis

10436022

TgenePICALM

GO:1905224

clathrin-coated pit assembly

16262731


check buttonFusion gene breakpoints across TMOD3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across PICALM (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-06-0878-01ATMOD3chr15

52194233

+PICALMchr11

85722179

-


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Fusion Gene ORF analysis for TMOD3-PICALM

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000308580ENST00000532317TMOD3chr15

52194233

+PICALMchr11

85722179

-
In-frameENST00000308580ENST00000526033TMOD3chr15

52194233

+PICALMchr11

85722179

-
In-frameENST00000308580ENST00000393346TMOD3chr15

52194233

+PICALMchr11

85722179

-
In-frameENST00000308580ENST00000528398TMOD3chr15

52194233

+PICALMchr11

85722179

-
In-frameENST00000308580ENST00000356360TMOD3chr15

52194233

+PICALMchr11

85722179

-
5CDS-intronENST00000308580ENST00000528411TMOD3chr15

52194233

+PICALMchr11

85722179

-
In-frameENST00000544199ENST00000532317TMOD3chr15

52194233

+PICALMchr11

85722179

-
In-frameENST00000544199ENST00000526033TMOD3chr15

52194233

+PICALMchr11

85722179

-
In-frameENST00000544199ENST00000393346TMOD3chr15

52194233

+PICALMchr11

85722179

-
In-frameENST00000544199ENST00000528398TMOD3chr15

52194233

+PICALMchr11

85722179

-
In-frameENST00000544199ENST00000356360TMOD3chr15

52194233

+PICALMchr11

85722179

-
5CDS-intronENST00000544199ENST00000528411TMOD3chr15

52194233

+PICALMchr11

85722179

-
intron-3CDSENST00000561136ENST00000532317TMOD3chr15

52194233

+PICALMchr11

85722179

-
intron-3CDSENST00000561136ENST00000526033TMOD3chr15

52194233

+PICALMchr11

85722179

-
intron-3CDSENST00000561136ENST00000393346TMOD3chr15

52194233

+PICALMchr11

85722179

-
intron-3CDSENST00000561136ENST00000528398TMOD3chr15

52194233

+PICALMchr11

85722179

-
intron-3CDSENST00000561136ENST00000356360TMOD3chr15

52194233

+PICALMchr11

85722179

-
intron-intronENST00000561136ENST00000528411TMOD3chr15

52194233

+PICALMchr11

85722179

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000308580TMOD3chr1552194233+ENST00000532317PICALMchr1185722179-384213052722479735
ENST00000308580TMOD3chr1552194233+ENST00000526033PICALMchr1185722179-394313052722584770
ENST00000308580TMOD3chr1552194233+ENST00000393346PICALMchr1185722179-283813052722605777
ENST00000308580TMOD3chr1552194233+ENST00000528398PICALMchr1185722179-266313052722455727
ENST00000308580TMOD3chr1552194233+ENST00000356360PICALMchr1185722179-260513052722545757
ENST00000544199TMOD3chr1552194233+ENST00000532317PICALMchr1185722179-36081071382245735
ENST00000544199TMOD3chr1552194233+ENST00000526033PICALMchr1185722179-37091071382350770
ENST00000544199TMOD3chr1552194233+ENST00000393346PICALMchr1185722179-26041071382371777
ENST00000544199TMOD3chr1552194233+ENST00000528398PICALMchr1185722179-24291071382221727
ENST00000544199TMOD3chr1552194233+ENST00000356360PICALMchr1185722179-23711071382311757

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000308580ENST00000532317TMOD3chr1552194233+PICALMchr1185722179-0.0006662040.9993338
ENST00000308580ENST00000526033TMOD3chr1552194233+PICALMchr1185722179-0.0006229340.9993771
ENST00000308580ENST00000393346TMOD3chr1552194233+PICALMchr1185722179-0.0014368940.9985631
ENST00000308580ENST00000528398TMOD3chr1552194233+PICALMchr1185722179-0.0015522070.9984478
ENST00000308580ENST00000356360TMOD3chr1552194233+PICALMchr1185722179-0.0015648830.9984351
ENST00000544199ENST00000532317TMOD3chr1552194233+PICALMchr1185722179-0.0006640080.99933594
ENST00000544199ENST00000526033TMOD3chr1552194233+PICALMchr1185722179-0.0006311870.99936885
ENST00000544199ENST00000393346TMOD3chr1552194233+PICALMchr1185722179-0.0014934860.9985065
ENST00000544199ENST00000528398TMOD3chr1552194233+PICALMchr1185722179-0.0015631550.99843687
ENST00000544199ENST00000356360TMOD3chr1552194233+PICALMchr1185722179-0.0016981360.99830186

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Fusion Genomic Features for TMOD3-PICALM


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TMOD3-PICALM


check button Go to

FGviewer for the breakpoints of chr15:52194233-chr11:85722179

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.PICALM

Q13492

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Cytoplasmic adapter protein that plays a critical role in clathrin-mediated endocytosis which is important in processes such as internalization of cell receptors, synaptic transmission or removal of apoptotic cells. Recruits AP-2 and attaches clathrin triskelions to the cytoplasmic side of plasma membrane leading to clathrin-coated vesicles (CCVs) assembly (PubMed:10436022, PubMed:16262731, PubMed:27574975). Furthermore, regulates clathrin-coated vesicle size and maturation by directly sensing and driving membrane curvature (PubMed:25898166). In addition to binding to clathrin, mediates the endocytosis of small R-SNARES (Soluble NSF Attachment Protein REceptors) between plasma membranes and endosomes including VAMP2, VAMP3, VAMP4, VAMP7 or VAMP8 (PubMed:22118466, PubMed:21808019, PubMed:23741335). In turn, PICALM-dependent SNARE endocytosis is required for the formation and maturation of autophagic precursors (PubMed:25241929). Modulates thereby autophagy and the turnover of autophagy substrates such as MAPT/TAU or amyloid precursor protein cleaved C-terminal fragment (APP-CTF) (PubMed:25241929, PubMed:24067654). {ECO:0000269|PubMed:10436022, ECO:0000269|PubMed:16262731, ECO:0000269|PubMed:21808019, ECO:0000269|PubMed:22118466, ECO:0000269|PubMed:23741335, ECO:0000269|PubMed:24067654, ECO:0000269|PubMed:25241929, ECO:0000269|PubMed:25898166, ECO:0000269|PubMed:27574975}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePICALMchr15:52194233chr11:85722179ENST0000035636051914_145219.33333333333334633.0DomainENTH
TgenePICALMchr15:52194233chr11:85722179ENST0000039334652014_145219.33333333333334653.0DomainENTH
TgenePICALMchr15:52194233chr11:85722179ENST0000052603352014_145219.33333333333334646.0DomainENTH
TgenePICALMchr15:52194233chr11:85722179ENST0000052839851914_145168.33333333333334552.0DomainENTH
TgenePICALMchr15:52194233chr11:85722179ENST0000053231752014_145219.33333333333334611.0DomainENTH


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Fusion Gene Sequence for TMOD3-PICALM


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000308580_ENST00000532317_TCGA-06-0878-01A_TMOD3_chr15_52194233_+_PICALM_chr11_85722179_length(transcript)=3842nt_BP=1305nt
GAGTGCGCACGCGCGTCGGAGGCGAAGGAGGAACCCACCGCACCTACAGGGCGGTCGAGTGAGGGAGCTGCTGGCGGGTGGGTCTGGCAA
CTCTTTGGGAGGCCGACGCGGGCGGACCGGCGGGTGCTGGGAACCGAGCCTCGGCTTGCGGCCGGCAGTTTCCGTGGGTCTGTGAAGAGG
TCGGCGGCCCCTGCGGGCGCCAGTCAGCTTTAAGAAAAAGTAGAGATCACTTCTGACTGTACTGAACAGCAAAAATTAAGTGACTTGCTG
CCCTGCACATCATGGCACTGCCATTCCGTAAGGACTTAGAAAAGTACAAAGACCTTGATGAAGATGAGCTCCTTGGGAATCTGTCAGAAA
CAGAACTGAAACAACTGGAAACTGTTTTGGATGATCTTGACCCCGAGAATGCCCTTCTGCCTGCAGGGTTCCGGCAGAAGAACCAGACAT
CAAAGTCCACCACAGGGCCATTTGATAGAGAGCATCTCCTTTCATATCTGGAGAAAGAAGCATTGGAGCATAAAGACAGGGAAGACTATG
TGCCCTACACTGGAGAAAAAAAAGGGAAAATATTTATCCCCAAACAGAAACCTGTACAGACTTTTACAGAAGAAAAAGTGTCTCTTGATC
CAGAATTAGAAGAAGCTTTGACAAGTGCTTCTGATACAGAATTGTGTGACCTCGCAGCAATTCTTGGGATGCACAATTTGATAACGAATA
CAAAGTTCTGTAATATAATGGGAAGTAGTAATGGTGTTGACCAAGAACATTTTTCAAATGTGGTCAAAGGTGAAAAGATTCTTCCGGTAT
TTGATGAGCCACCAAATCCAACCAATGTAGAAGAGAGTTTGAAGAGAACTAAAGAAAACGATGCTCATCTTGTTGAAGTTAATTTGAATA
ATATAAAGAATATCCCAATTCCAACCCTAAAAGATTTTGCAAAGGCTTTGGAAACCAACACACATGTGAAATGTTTCAGTCTTGCAGCCA
CCCGGAGCAATGACCCTGTTGCTACTGCTTTTGCAGAAATGCTGAAAGTGAACAAAACTTTGAAGAGCTTAAATGTGGAGTCCAACTTTA
TCACGGGAGTTGGGATTCTGGCACTGATTGATGCGTTAAGAGATAATGAAACCCTGGCAGAGCTCAAGATTGACAATCAGAGGCAGCAGT
TGGGGACAGCTGTAGAATTGGAAATGGCCAAGATGCTTGAGGAAAATACAAATATCCTTAAATTTGGATATCAGTTTACACAGCAGGGAC
CACGAACCAGAGCAGCTAATGCTATAACAAAAAACAATGACTTAGAAAAATATTTTGATATGAAAAAGAACCAATGCAAAGAAGGTCTTG
ACATCTATAAGAAGTTCCTAACTAGGATGACAAGAATCTCAGAGTTCCTCAAAGTTGCAGAGCAAGTTGGAATTGACAGAGGTGATATAC
CAGACCTTTCACAGGCCCCTAGCAGTCTTCTTGATGCTTTGGAACAACATTTAGCTTCCTTGGAAGGAAAGAAAATCAAAGATTCTACAG
CTGCAAGCAGGGCAACTACACTTTCCAATGCAGTGTCTTCCCTGGCAAGCACTGGTCTATCTCTGACCAAAGTGGATGAAAGGGAAAAGC
AGGCAGCATTAGAGGAAGAACAGGCACGTTTGAAAGCTTTAAAGGAACAGCGCCTAAAAGAACTTGCAAAGAAACCTCATACCTCTTTAA
CAACTGCAGCCTCTCCTGTATCCACCTCAGCAGGAGGGATAATGACTGCACCAGCCATTGACATATTTTCTACCCCTAGTTCTTCTAACA
GCACATCAAAGCTGCCCAATGATCTGCTTGATTTGCAGCAGCCAACTTTTCACCCATCTGTACATCCTATGTCAACTGCTTCTCAGGTAG
CAAGTACATGGGGAGGATTCACTCCTTCTCCAGTTGCACAGCCACACCCTTCAGCTGGCCTTAATGTTGACTTTGAATCTGTGTTTGGAA
ATAAATCTACAAATGTTATTGTAGATTCTGGGGGCTTTGATGAACTAGGTGGACTTCTCAAACCAACAGTGGCCTCTCAGAACCAGAACC
TTCCTGTTGCCAAACTCCCACCTAGCAAGTTAGTATCTGATGACTTGGATTCATCTTTAGCCAACCTTGTGGGCAATCTTGGCATCGGAA
ATGGAACCACTAAGAATGATGTAAATTGGAGTCAACCAGGTGAAAAGAAGTTAACTGGGGGATCTAACTGGCAACCAAAGGTTGCACCAA
CAACCGCTTGGAATGCTGCAACAATGAATGGCATGCATTTTCCACAATACGCACCCCCTGTAATGGCCTATCCTGCTACTACACCAACAG
GCATGATAGGATATGGAATTCCTCCACAAATGGGAAGTGTTCCTGTAATGACGCAACCAACCTTAATATACAGCCAGCCTGTCATGAGAC
CTCCAAACCCCTTTGGCCCTGTATCAGGAGCACAGATACAGTTTATGTAACTTGATGGAAGAAAATGGAATTACTCCAAAAAGACAAGTG
CTCAAGCAGCAAAATCCTTACTTCCAGCAAAATCCAAACTGCTGTCTCTTAAATCTCTTAAACTCTCTTCTTCCATTAGAATGCTACAAG
TAACTCAGTGAAGGCCCATGAAGGAAATTGGGACTAGTTTATAGGAGAACGTATCAATACAGTTTATAAAGCCAAGAATTGCTATGATTT
AAGACTAAGATCTGTCTTTTTGGTGACTAACCCTTCAATTCTTTCAACTCCTGTTAATACCCATAATCAGTAACCTATCAAGAAAAGCCC
TTATTTGGAAAGTGTGAAATTTGTATTTGGAAAAGCTGCCTGGAGAGAAGAACTGTGTCCTTTACTGTATTTCAACAGGACTCTTTTGGG
GGATCAAAATTAAAATTCCTAATTATGCATTATCTTTCTTTTCTCCAGTCCTCACAAATACAGAAACAATAACTGAAATTAACTTTTCTT
TTTTTAAAAAAAATTATATTCAGTTTGCAGTAGACATTCCTTAAGTATTTGTATTTATTTATGATTATCAATTTTACATAACATTAATAT
TGTATCAGACCTCCTTATGAAAATGAGTATGGATGTGCACAGTATGTTTGATTTTTATCCACAAGAATGAATCTGATTCAGAATGCTTTT
CTCAGCTGACATACAGAGCACTAAATATTTTAAGGCAAGTCCATAGGTCTGAATCTCTTAAGAATTCTCGGCCTCTGTGGGATTTAGGGA
AGCATTATAAATGCATTAATCCTTATAGTCAATTCTGTGCCTAGGATTTTGCCAGGGAACAGTTCACTGACTAGGAAAAGCACTACATTT
TAAATTCAGCATTAGTGCATTGGGAAGGATCTTTACTGCTTTGTGCTTGGCATGTCATTATTTTCCATTTGACATTAGGGCCTTTCCAAA
ATGAATGTGAGGAATTGCTTTCACTTCAAGACTTTCCTTCTTTTCACTAAAACTCTAGAAGGTGTTACAAGGGGGAGGGAAGGGGGGCAA
AGTCCTTGAACATTTTCTTTGGCTCGTGCCATGTTATGATCATATACCTTTTAAATAAGGGGAAATAGTATCTTTAAAGTTAATGTCTAG
CCAAGAGTTTAGTAAACGAAGAATTAAACTGCACTGTTGATCGGTGCTTTGTGTAAATACATCTTTAACATTTGGGTGGAGAGGGGCCTT
AAGAAGGACAGTTCATTGTAGGAAAGCAATTCTGTACATGAGTTTAAGCATTCTTGTTGCATTGTCTCTGCAGATTCTATTTTTGTTTAC

>In-frame_ENST00000308580_ENST00000532317_TCGA-06-0878-01A_TMOD3_chr15_52194233_+_PICALM_chr11_85722179_length(amino acids)=735AA_start in transcript=272_stop in transcript=2479
MHIMALPFRKDLEKYKDLDEDELLGNLSETELKQLETVLDDLDPENALLPAGFRQKNQTSKSTTGPFDREHLLSYLEKEALEHKDREDYV
PYTGEKKGKIFIPKQKPVQTFTEEKVSLDPELEEALTSASDTELCDLAAILGMHNLITNTKFCNIMGSSNGVDQEHFSNVVKGEKILPVF
DEPPNPTNVEESLKRTKENDAHLVEVNLNNIKNIPIPTLKDFAKALETNTHVKCFSLAATRSNDPVATAFAEMLKVNKTLKSLNVESNFI
TGVGILALIDALRDNETLAELKIDNQRQQLGTAVELEMAKMLEENTNILKFGYQFTQQGPRTRAANAITKNNDLEKYFDMKKNQCKEGLD
IYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQ
AALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVA
STWGGFTPSPVAQPHPSAGLNVDFESVFGNKSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKLPPSKLVSDDLDSSLANLVGNLGIGN
GTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMNGMHFPQYAPPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPTLIYSQPVMRP

--------------------------------------------------------------
>In-frame_ENST00000308580_ENST00000526033_TCGA-06-0878-01A_TMOD3_chr15_52194233_+_PICALM_chr11_85722179_length(transcript)=3943nt_BP=1305nt
GAGTGCGCACGCGCGTCGGAGGCGAAGGAGGAACCCACCGCACCTACAGGGCGGTCGAGTGAGGGAGCTGCTGGCGGGTGGGTCTGGCAA
CTCTTTGGGAGGCCGACGCGGGCGGACCGGCGGGTGCTGGGAACCGAGCCTCGGCTTGCGGCCGGCAGTTTCCGTGGGTCTGTGAAGAGG
TCGGCGGCCCCTGCGGGCGCCAGTCAGCTTTAAGAAAAAGTAGAGATCACTTCTGACTGTACTGAACAGCAAAAATTAAGTGACTTGCTG
CCCTGCACATCATGGCACTGCCATTCCGTAAGGACTTAGAAAAGTACAAAGACCTTGATGAAGATGAGCTCCTTGGGAATCTGTCAGAAA
CAGAACTGAAACAACTGGAAACTGTTTTGGATGATCTTGACCCCGAGAATGCCCTTCTGCCTGCAGGGTTCCGGCAGAAGAACCAGACAT
CAAAGTCCACCACAGGGCCATTTGATAGAGAGCATCTCCTTTCATATCTGGAGAAAGAAGCATTGGAGCATAAAGACAGGGAAGACTATG
TGCCCTACACTGGAGAAAAAAAAGGGAAAATATTTATCCCCAAACAGAAACCTGTACAGACTTTTACAGAAGAAAAAGTGTCTCTTGATC
CAGAATTAGAAGAAGCTTTGACAAGTGCTTCTGATACAGAATTGTGTGACCTCGCAGCAATTCTTGGGATGCACAATTTGATAACGAATA
CAAAGTTCTGTAATATAATGGGAAGTAGTAATGGTGTTGACCAAGAACATTTTTCAAATGTGGTCAAAGGTGAAAAGATTCTTCCGGTAT
TTGATGAGCCACCAAATCCAACCAATGTAGAAGAGAGTTTGAAGAGAACTAAAGAAAACGATGCTCATCTTGTTGAAGTTAATTTGAATA
ATATAAAGAATATCCCAATTCCAACCCTAAAAGATTTTGCAAAGGCTTTGGAAACCAACACACATGTGAAATGTTTCAGTCTTGCAGCCA
CCCGGAGCAATGACCCTGTTGCTACTGCTTTTGCAGAAATGCTGAAAGTGAACAAAACTTTGAAGAGCTTAAATGTGGAGTCCAACTTTA
TCACGGGAGTTGGGATTCTGGCACTGATTGATGCGTTAAGAGATAATGAAACCCTGGCAGAGCTCAAGATTGACAATCAGAGGCAGCAGT
TGGGGACAGCTGTAGAATTGGAAATGGCCAAGATGCTTGAGGAAAATACAAATATCCTTAAATTTGGATATCAGTTTACACAGCAGGGAC
CACGAACCAGAGCAGCTAATGCTATAACAAAAAACAATGACTTAGAAAAATATTTTGATATGAAAAAGAACCAATGCAAAGAAGGTCTTG
ACATCTATAAGAAGTTCCTAACTAGGATGACAAGAATCTCAGAGTTCCTCAAAGTTGCAGAGCAAGTTGGAATTGACAGAGGTGATATAC
CAGACCTTTCACAGGCCCCTAGCAGTCTTCTTGATGCTTTGGAACAACATTTAGCTTCCTTGGAAGGAAAGAAAATCAAAGATTCTACAG
CTGCAAGCAGGGCAACTACACTTTCCAATGCAGTGTCTTCCCTGGCAAGCACTGGTCTATCTCTGACCAAAGTGGATGAAAGGGAAAAGC
AGGCAGCATTAGAGGAAGAACAGGCACGTTTGAAAGCTTTAAAGGAACAGCGCCTAAAAGAACTTGCAAAGAAACCTCATACCTCTTTAA
CAACTGCAGCCTCTCCTGTATCCACCTCAGCAGGAGGGATAATGACTGCACCAGCCATTGACATATTTTCTACCCCTAGTTCTTCTAACA
GCACATCAAAGCTGCCCAATGATCTGCTTGATTTGCAGCAGCCAACTTTTCACCCATCTGTACATCCTATGTCAACTGCTTCTCAGGTAG
CAAGTACATGGGGAGATGCTGTTGATGATGCCATTCCAAGCTTAAATCCTTTCCTCACAAAAAGTAGTGGTGATGTTCACCTTTCCATTT
CTTCAGATGTATCTACTTTTACTACTAGGACACCTACTCATGAAATGTTTGTTGGATTCACTCCTTCTCCAGTTGCACAGCCACACCCTT
CAGCTGGCCTTAATGTTGACTTTGAATCTGTGTTTGGAAATAAATCTACAAATGTTATTGTAGATTCTGGGGGCTTTGATGAACTAGGTG
GACTTCTCAAACCAACAGTGGCCTCTCAGAACCAGAACCTTCCTGTTGCCAAACTCCCACCTAGCAAGTTAGTATCTGATGACTTGGATT
CATCTTTAGCCAACCTTGTGGGCAATCTTGGCATCGGAAATGGAACCACTAAGAATGATGTAAATTGGAGTCAACCAGGTGAAAAGAAGT
TAACTGGGGGATCTAACTGGCAACCAAAGGTTGCACCAACAACCGCTTGGAATGCTGCAACAATGGCACCCCCTGTAATGGCCTATCCTG
CTACTACACCAACAGGCATGATAGGATATGGAATTCCTCCACAAATGGGAAGTGTTCCTGTAATGACGCAACCAACCTTAATATACAGCC
AGCCTGTCATGAGACCTCCAAACCCCTTTGGCCCTGTATCAGGAGCACAGATACAGTTTATGTAACTTGATGGAAGAAAATGGAATTACT
CCAAAAAGACAAGTGCTCAAGCAGCAAAATCCTTACTTCCAGCAAAATCCAAACTGCTGTCTCTTAAATCTCTTAAACTCTCTTCTTCCA
TTAGAATGCTACAAGTAACTCAGTGAAGGCCCATGAAGGAAATTGGGACTAGTTTATAGGAGAACGTATCAATACAGTTTATAAAGCCAA
GAATTGCTATGATTTAAGACTAAGATCTGTCTTTTTGGTGACTAACCCTTCAATTCTTTCAACTCCTGTTAATACCCATAATCAGTAACC
TATCAAGAAAAGCCCTTATTTGGAAAGTGTGAAATTTGTATTTGGAAAAGCTGCCTGGAGAGAAGAACTGTGTCCTTTACTGTATTTCAA
CAGGACTCTTTTGGGGGATCAAAATTAAAATTCCTAATTATGCATTATCTTTCTTTTCTCCAGTCCTCACAAATACAGAAACAATAACTG
AAATTAACTTTTCTTTTTTTAAAAAAAATTATATTCAGTTTGCAGTAGACATTCCTTAAGTATTTGTATTTATTTATGATTATCAATTTT
ACATAACATTAATATTGTATCAGACCTCCTTATGAAAATGAGTATGGATGTGCACAGTATGTTTGATTTTTATCCACAAGAATGAATCTG
ATTCAGAATGCTTTTCTCAGCTGACATACAGAGCACTAAATATTTTAAGGCAAGTCCATAGGTCTGAATCTCTTAAGAATTCTCGGCCTC
TGTGGGATTTAGGGAAGCATTATAAATGCATTAATCCTTATAGTCAATTCTGTGCCTAGGATTTTGCCAGGGAACAGTTCACTGACTAGG
AAAAGCACTACATTTTAAATTCAGCATTAGTGCATTGGGAAGGATCTTTACTGCTTTGTGCTTGGCATGTCATTATTTTCCATTTGACAT
TAGGGCCTTTCCAAAATGAATGTGAGGAATTGCTTTCACTTCAAGACTTTCCTTCTTTTCACTAAAACTCTAGAAGGTGTTACAAGGGGG
AGGGAAGGGGGGCAAAGTCCTTGAACATTTTCTTTGGCTCGTGCCATGTTATGATCATATACCTTTTAAATAAGGGGAAATAGTATCTTT
AAAGTTAATGTCTAGCCAAGAGTTTAGTAAACGAAGAATTAAACTGCACTGTTGATCGGTGCTTTGTGTAAATACATCTTTAACATTTGG
GTGGAGAGGGGCCTTAAGAAGGACAGTTCATTGTAGGAAAGCAATTCTGTACATGAGTTTAAGCATTCTTGTTGCATTGTCTCTGCAGAT

>In-frame_ENST00000308580_ENST00000526033_TCGA-06-0878-01A_TMOD3_chr15_52194233_+_PICALM_chr11_85722179_length(amino acids)=770AA_start in transcript=272_stop in transcript=2584
MHIMALPFRKDLEKYKDLDEDELLGNLSETELKQLETVLDDLDPENALLPAGFRQKNQTSKSTTGPFDREHLLSYLEKEALEHKDREDYV
PYTGEKKGKIFIPKQKPVQTFTEEKVSLDPELEEALTSASDTELCDLAAILGMHNLITNTKFCNIMGSSNGVDQEHFSNVVKGEKILPVF
DEPPNPTNVEESLKRTKENDAHLVEVNLNNIKNIPIPTLKDFAKALETNTHVKCFSLAATRSNDPVATAFAEMLKVNKTLKSLNVESNFI
TGVGILALIDALRDNETLAELKIDNQRQQLGTAVELEMAKMLEENTNILKFGYQFTQQGPRTRAANAITKNNDLEKYFDMKKNQCKEGLD
IYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQ
AALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVA
STWGDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTRTPTHEMFVGFTPSPVAQPHPSAGLNVDFESVFGNKSTNVIVDSGGFDELGG
LLKPTVASQNQNLPVAKLPPSKLVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMAPPVMAYPA

--------------------------------------------------------------
>In-frame_ENST00000308580_ENST00000393346_TCGA-06-0878-01A_TMOD3_chr15_52194233_+_PICALM_chr11_85722179_length(transcript)=2838nt_BP=1305nt
GAGTGCGCACGCGCGTCGGAGGCGAAGGAGGAACCCACCGCACCTACAGGGCGGTCGAGTGAGGGAGCTGCTGGCGGGTGGGTCTGGCAA
CTCTTTGGGAGGCCGACGCGGGCGGACCGGCGGGTGCTGGGAACCGAGCCTCGGCTTGCGGCCGGCAGTTTCCGTGGGTCTGTGAAGAGG
TCGGCGGCCCCTGCGGGCGCCAGTCAGCTTTAAGAAAAAGTAGAGATCACTTCTGACTGTACTGAACAGCAAAAATTAAGTGACTTGCTG
CCCTGCACATCATGGCACTGCCATTCCGTAAGGACTTAGAAAAGTACAAAGACCTTGATGAAGATGAGCTCCTTGGGAATCTGTCAGAAA
CAGAACTGAAACAACTGGAAACTGTTTTGGATGATCTTGACCCCGAGAATGCCCTTCTGCCTGCAGGGTTCCGGCAGAAGAACCAGACAT
CAAAGTCCACCACAGGGCCATTTGATAGAGAGCATCTCCTTTCATATCTGGAGAAAGAAGCATTGGAGCATAAAGACAGGGAAGACTATG
TGCCCTACACTGGAGAAAAAAAAGGGAAAATATTTATCCCCAAACAGAAACCTGTACAGACTTTTACAGAAGAAAAAGTGTCTCTTGATC
CAGAATTAGAAGAAGCTTTGACAAGTGCTTCTGATACAGAATTGTGTGACCTCGCAGCAATTCTTGGGATGCACAATTTGATAACGAATA
CAAAGTTCTGTAATATAATGGGAAGTAGTAATGGTGTTGACCAAGAACATTTTTCAAATGTGGTCAAAGGTGAAAAGATTCTTCCGGTAT
TTGATGAGCCACCAAATCCAACCAATGTAGAAGAGAGTTTGAAGAGAACTAAAGAAAACGATGCTCATCTTGTTGAAGTTAATTTGAATA
ATATAAAGAATATCCCAATTCCAACCCTAAAAGATTTTGCAAAGGCTTTGGAAACCAACACACATGTGAAATGTTTCAGTCTTGCAGCCA
CCCGGAGCAATGACCCTGTTGCTACTGCTTTTGCAGAAATGCTGAAAGTGAACAAAACTTTGAAGAGCTTAAATGTGGAGTCCAACTTTA
TCACGGGAGTTGGGATTCTGGCACTGATTGATGCGTTAAGAGATAATGAAACCCTGGCAGAGCTCAAGATTGACAATCAGAGGCAGCAGT
TGGGGACAGCTGTAGAATTGGAAATGGCCAAGATGCTTGAGGAAAATACAAATATCCTTAAATTTGGATATCAGTTTACACAGCAGGGAC
CACGAACCAGAGCAGCTAATGCTATAACAAAAAACAATGACTTAGAAAAATATTTTGATATGAAAAAGAACCAATGCAAAGAAGGTCTTG
ACATCTATAAGAAGTTCCTAACTAGGATGACAAGAATCTCAGAGTTCCTCAAAGTTGCAGAGCAAGTTGGAATTGACAGAGGTGATATAC
CAGACCTTTCACAGGCCCCTAGCAGTCTTCTTGATGCTTTGGAACAACATTTAGCTTCCTTGGAAGGAAAGAAAATCAAAGATTCTACAG
CTGCAAGCAGGGCAACTACACTTTCCAATGCAGTGTCTTCCCTGGCAAGCACTGGTCTATCTCTGACCAAAGTGGATGAAAGGGAAAAGC
AGGCAGCATTAGAGGAAGAACAGGCACGTTTGAAAGCTTTAAAGGAACAGCGCCTAAAAGAACTTGCAAAGAAACCTCATACCTCTTTAA
CAACTGCAGCCTCTCCTGTATCCACCTCAGCAGGAGGGATAATGACTGCACCAGCCATTGACATATTTTCTACCCCTAGTTCTTCTAACA
GCACATCAAAGCTGCCCAATGATCTGCTTGATTTGCAGCAGCCAACTTTTCACCCATCTGTACATCCTATGTCAACTGCTTCTCAGGTAG
CAAGTACATGGGGAGATCCTTTCTCTGCTACTGTAGATGCTGTTGATGATGCCATTCCAAGCTTAAATCCTTTCCTCACAAAAAGTAGTG
GTGATGTTCACCTTTCCATTTCTTCAGATGTATCTACTTTTACTACTAGGACACCTACTCATGAAATGTTTGTTGGATTCACTCCTTCTC
CAGTTGCACAGCCACACCCTTCAGCTGGCCTTAATGTTGACTTTGAATCTGTGTTTGGAAATAAATCTACAAATGTTATTGTAGATTCTG
GGGGCTTTGATGAACTAGGTGGACTTCTCAAACCAACAGTGGCCTCTCAGAACCAGAACCTTCCTGTTGCCAAACTCCCACCTAGCAAGT
TAGTATCTGATGACTTGGATTCATCTTTAGCCAACCTTGTGGGCAATCTTGGCATCGGAAATGGAACCACTAAGAATGATGTAAATTGGA
GTCAACCAGGTGAAAAGAAGTTAACTGGGGGATCTAACTGGCAACCAAAGGTTGCACCAACAACCGCTTGGAATGCTGCAACAATGGCAC
CCCCTGTAATGGCCTATCCTGCTACTACACCAACAGGCATGATAGGATATGGAATTCCTCCACAAATGGGAAGTGTTCCTGTAATGACGC
AACCAACCTTAATATACAGCCAGCCTGTCATGAGACCTCCAAACCCCTTTGGCCCTGTATCAGGAGCACAGATACAGTTTATGTAACTTG
ATGGAAGAAAATGGAATTACTCCAAAAAGACAAGTGCTCAAGCAGCAAAATCCTTACTTCCAGCAAAATCCAAACTGCTGTCTCTTAAAT
CTCTTAAACTCTCTTCTTCCATTAGAATGCTACAAGTAACTCAGTGAAGGCCCATGAAGGAAATTGGGACTAGTTTATAGGAGAACGTAT

>In-frame_ENST00000308580_ENST00000393346_TCGA-06-0878-01A_TMOD3_chr15_52194233_+_PICALM_chr11_85722179_length(amino acids)=777AA_start in transcript=272_stop in transcript=2605
MHIMALPFRKDLEKYKDLDEDELLGNLSETELKQLETVLDDLDPENALLPAGFRQKNQTSKSTTGPFDREHLLSYLEKEALEHKDREDYV
PYTGEKKGKIFIPKQKPVQTFTEEKVSLDPELEEALTSASDTELCDLAAILGMHNLITNTKFCNIMGSSNGVDQEHFSNVVKGEKILPVF
DEPPNPTNVEESLKRTKENDAHLVEVNLNNIKNIPIPTLKDFAKALETNTHVKCFSLAATRSNDPVATAFAEMLKVNKTLKSLNVESNFI
TGVGILALIDALRDNETLAELKIDNQRQQLGTAVELEMAKMLEENTNILKFGYQFTQQGPRTRAANAITKNNDLEKYFDMKKNQCKEGLD
IYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQ
AALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVA
STWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTRTPTHEMFVGFTPSPVAQPHPSAGLNVDFESVFGNKSTNVIVDSG
GFDELGGLLKPTVASQNQNLPVAKLPPSKLVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMAP

--------------------------------------------------------------
>In-frame_ENST00000308580_ENST00000528398_TCGA-06-0878-01A_TMOD3_chr15_52194233_+_PICALM_chr11_85722179_length(transcript)=2663nt_BP=1305nt
GAGTGCGCACGCGCGTCGGAGGCGAAGGAGGAACCCACCGCACCTACAGGGCGGTCGAGTGAGGGAGCTGCTGGCGGGTGGGTCTGGCAA
CTCTTTGGGAGGCCGACGCGGGCGGACCGGCGGGTGCTGGGAACCGAGCCTCGGCTTGCGGCCGGCAGTTTCCGTGGGTCTGTGAAGAGG
TCGGCGGCCCCTGCGGGCGCCAGTCAGCTTTAAGAAAAAGTAGAGATCACTTCTGACTGTACTGAACAGCAAAAATTAAGTGACTTGCTG
CCCTGCACATCATGGCACTGCCATTCCGTAAGGACTTAGAAAAGTACAAAGACCTTGATGAAGATGAGCTCCTTGGGAATCTGTCAGAAA
CAGAACTGAAACAACTGGAAACTGTTTTGGATGATCTTGACCCCGAGAATGCCCTTCTGCCTGCAGGGTTCCGGCAGAAGAACCAGACAT
CAAAGTCCACCACAGGGCCATTTGATAGAGAGCATCTCCTTTCATATCTGGAGAAAGAAGCATTGGAGCATAAAGACAGGGAAGACTATG
TGCCCTACACTGGAGAAAAAAAAGGGAAAATATTTATCCCCAAACAGAAACCTGTACAGACTTTTACAGAAGAAAAAGTGTCTCTTGATC
CAGAATTAGAAGAAGCTTTGACAAGTGCTTCTGATACAGAATTGTGTGACCTCGCAGCAATTCTTGGGATGCACAATTTGATAACGAATA
CAAAGTTCTGTAATATAATGGGAAGTAGTAATGGTGTTGACCAAGAACATTTTTCAAATGTGGTCAAAGGTGAAAAGATTCTTCCGGTAT
TTGATGAGCCACCAAATCCAACCAATGTAGAAGAGAGTTTGAAGAGAACTAAAGAAAACGATGCTCATCTTGTTGAAGTTAATTTGAATA
ATATAAAGAATATCCCAATTCCAACCCTAAAAGATTTTGCAAAGGCTTTGGAAACCAACACACATGTGAAATGTTTCAGTCTTGCAGCCA
CCCGGAGCAATGACCCTGTTGCTACTGCTTTTGCAGAAATGCTGAAAGTGAACAAAACTTTGAAGAGCTTAAATGTGGAGTCCAACTTTA
TCACGGGAGTTGGGATTCTGGCACTGATTGATGCGTTAAGAGATAATGAAACCCTGGCAGAGCTCAAGATTGACAATCAGAGGCAGCAGT
TGGGGACAGCTGTAGAATTGGAAATGGCCAAGATGCTTGAGGAAAATACAAATATCCTTAAATTTGGATATCAGTTTACACAGCAGGGAC
CACGAACCAGAGCAGCTAATGCTATAACAAAAAACAATGACTTAGAAAAATATTTTGATATGAAAAAGAACCAATGCAAAGAAGGTCTTG
ACATCTATAAGAAGTTCCTAACTAGGATGACAAGAATCTCAGAGTTCCTCAAAGTTGCAGAGCAAGTTGGAATTGACAGAGGTGATATAC
CAGACCTTTCACAGGCCCCTAGCAGTCTTCTTGATGCTTTGGAACAACATTTAGCTTCCTTGGAAGGAAAGAAAATCAAAGATTCTACAG
CTGCAAGCAGGGCAACTACACTTTCCAATGCAGTGTCTTCCCTGGCAAGCACTGGTCTATCTCTGACCAAAGTGGATGAAAGGGAAAAGC
AGGCAGCATTAGAGGAAGAACAGGCACGTTTGAAAGCTTTAAAGGAACAGCGCCTAAAAGAACTTGCAAAGAAACCTCATACCTCTTTAA
CAACTGCAGCCTCTCCTGTATCCACCTCAGCAGGAGGGATAATGACTGCACCAGCCATTGACATATTTTCTACCCCTAGTTCTTCTAACA
GCACATCAAAGCTGCCCAATGATCTGCTTGATTTGCAGCAGCCAACTTTTCACCCATCTGTACATCCTATGTCAACTGCTTCTCAGGTAG
CAAGTACATGGGGAGGATTCACTCCTTCTCCAGTTGCACAGCCACACCCTTCAGCTGGCCTTAATGTTGACTTTGAATCTGTGTTTGGAA
ATAAATCTACAAATGTTATTGTAGATTCTGGGGGCTTTGATGAACTAGGTGGACTTCTCAAACCAACAGTGGCCTCTCAGAACCAGAACC
TTCCTGTTGCCAAACTCCCACCTAGCAAGTTAGTATCTGATGACTTGGATTCATCTTTAGCCAACCTTGTGGGCAATCTTGGCATCGGAA
ATGGAACCACTAAGAATGATGTAAATTGGAGTCAACCAGGTGAAAAGAAGTTAACTGGGGGATCTAACTGGCAACCAAAGGTTGCACCAA
CAACCGCTTGGAATGCTGCAACAATGGCACCCCCTGTAATGGCCTATCCTGCTACTACACCAACAGGCATGATAGGATATGGAATTCCTC
CACAAATGGGAAGTGTTCCTGTAATGACGCAACCAACCTTAATATACAGCCAGCCTGTCATGAGACCTCCAAACCCCTTTGGCCCTGTAT
CAGGAGCACAGATACAGTTTATGTAACTTGATGGAAGAAAATGGAATTACTCCAAAAAGACAAGTGCTCAAGCAGCAAAATCCTTACTTC
CAGCAAAATCCAAACTGCTGTCTCTTAAATCTCTTAAACTCTCTTCTTCCATTAGAATGCTACAAGTAACTCAGTGAAGGCCCATGAAGG

>In-frame_ENST00000308580_ENST00000528398_TCGA-06-0878-01A_TMOD3_chr15_52194233_+_PICALM_chr11_85722179_length(amino acids)=727AA_start in transcript=272_stop in transcript=2455
MHIMALPFRKDLEKYKDLDEDELLGNLSETELKQLETVLDDLDPENALLPAGFRQKNQTSKSTTGPFDREHLLSYLEKEALEHKDREDYV
PYTGEKKGKIFIPKQKPVQTFTEEKVSLDPELEEALTSASDTELCDLAAILGMHNLITNTKFCNIMGSSNGVDQEHFSNVVKGEKILPVF
DEPPNPTNVEESLKRTKENDAHLVEVNLNNIKNIPIPTLKDFAKALETNTHVKCFSLAATRSNDPVATAFAEMLKVNKTLKSLNVESNFI
TGVGILALIDALRDNETLAELKIDNQRQQLGTAVELEMAKMLEENTNILKFGYQFTQQGPRTRAANAITKNNDLEKYFDMKKNQCKEGLD
IYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQ
AALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVA
STWGGFTPSPVAQPHPSAGLNVDFESVFGNKSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKLPPSKLVSDDLDSSLANLVGNLGIGN
GTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMAPPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFGPVS

--------------------------------------------------------------
>In-frame_ENST00000308580_ENST00000356360_TCGA-06-0878-01A_TMOD3_chr15_52194233_+_PICALM_chr11_85722179_length(transcript)=2605nt_BP=1305nt
GAGTGCGCACGCGCGTCGGAGGCGAAGGAGGAACCCACCGCACCTACAGGGCGGTCGAGTGAGGGAGCTGCTGGCGGGTGGGTCTGGCAA
CTCTTTGGGAGGCCGACGCGGGCGGACCGGCGGGTGCTGGGAACCGAGCCTCGGCTTGCGGCCGGCAGTTTCCGTGGGTCTGTGAAGAGG
TCGGCGGCCCCTGCGGGCGCCAGTCAGCTTTAAGAAAAAGTAGAGATCACTTCTGACTGTACTGAACAGCAAAAATTAAGTGACTTGCTG
CCCTGCACATCATGGCACTGCCATTCCGTAAGGACTTAGAAAAGTACAAAGACCTTGATGAAGATGAGCTCCTTGGGAATCTGTCAGAAA
CAGAACTGAAACAACTGGAAACTGTTTTGGATGATCTTGACCCCGAGAATGCCCTTCTGCCTGCAGGGTTCCGGCAGAAGAACCAGACAT
CAAAGTCCACCACAGGGCCATTTGATAGAGAGCATCTCCTTTCATATCTGGAGAAAGAAGCATTGGAGCATAAAGACAGGGAAGACTATG
TGCCCTACACTGGAGAAAAAAAAGGGAAAATATTTATCCCCAAACAGAAACCTGTACAGACTTTTACAGAAGAAAAAGTGTCTCTTGATC
CAGAATTAGAAGAAGCTTTGACAAGTGCTTCTGATACAGAATTGTGTGACCTCGCAGCAATTCTTGGGATGCACAATTTGATAACGAATA
CAAAGTTCTGTAATATAATGGGAAGTAGTAATGGTGTTGACCAAGAACATTTTTCAAATGTGGTCAAAGGTGAAAAGATTCTTCCGGTAT
TTGATGAGCCACCAAATCCAACCAATGTAGAAGAGAGTTTGAAGAGAACTAAAGAAAACGATGCTCATCTTGTTGAAGTTAATTTGAATA
ATATAAAGAATATCCCAATTCCAACCCTAAAAGATTTTGCAAAGGCTTTGGAAACCAACACACATGTGAAATGTTTCAGTCTTGCAGCCA
CCCGGAGCAATGACCCTGTTGCTACTGCTTTTGCAGAAATGCTGAAAGTGAACAAAACTTTGAAGAGCTTAAATGTGGAGTCCAACTTTA
TCACGGGAGTTGGGATTCTGGCACTGATTGATGCGTTAAGAGATAATGAAACCCTGGCAGAGCTCAAGATTGACAATCAGAGGCAGCAGT
TGGGGACAGCTGTAGAATTGGAAATGGCCAAGATGCTTGAGGAAAATACAAATATCCTTAAATTTGGATATCAGTTTACACAGCAGGGAC
CACGAACCAGAGCAGCTAATGCTATAACAAAAAACAATGACTTAGAAAAATATTTTGATATGAAAAAGAACCAATGCAAAGAAGGTCTTG
ACATCTATAAGAAGTTCCTAACTAGGATGACAAGAATCTCAGAGTTCCTCAAAGTTGCAGAGCAAGTTGGAATTGACAGAGGTGATATAC
CAGACCTTTCACAGGCCCCTAGCAGTCTTCTTGATGCTTTGGAACAACATTTAGCTTCCTTGGAAGGAAAGAAAATCAAAGATTCTACAG
CTGCAAGCAGGGCAACTACACTTTCCAATGCAGTGTCTTCCCTGGCAAGCACTGGTCTATCTCTGACCAAAGTGGATGAAAGGGAAAAGC
AGGCAGCATTAGAGGAAGAACAGGCACGTTTGAAAGCTTTAAAGGAACAGCGCCTAAAAGAACTTGCAAAGAAACCTCATACCTCTTTAA
CAACTGCAGCCTCTCCTGTATCCACCTCAGCAGGAGGGATAATGACTGCACCAGCCATTGACATATTTTCTACCCCTAGTTCTTCTAACA
GCACATCAAAGCTGCCCAATGATCTGCTTGATTTGCAGCAGCCAACTTTTCACCCATCTGTACATCCTATGTCAACTGCTTCTCAGGTAG
CAAGTACATGGGGAGATCCTTTCTCTGCTACTGTAGATGCTGTTGATGATGCCATTCCAAGCTTAAATCCTTTCCTCACAAAAAGTAGTG
GTGATGTTCACCTTTCCATTTCTTCAGATGTATCTACTTTTACTACTAGGACACCTACTCATGAAATGTTTGTTGGATTCACTCCTTCTC
CAGTTGCACAGCCACACCCTTCAGCTGGCCTTAATGTTGACTTTGAATCTGTGTTTGGAAATAAATCTACAAATGTTATTGTAGATTCTG
GGGGCTTTGATGAACTAGGTGGACTTCTCAAACCAACAGTGGCCTCTCAGAACCAGAACCTTCCTGTTGCCAAACTCCCACCTAGCAAGT
TAGTATCTGATGACTTGGATTCATCTTTAGCCAACCTTGTGGGCAATCTTGGCATCGGAAATGGAACCACTAAGAATGATGTAAATTGGA
GTCAACCAGGTGAAAAGAAGTTAACTGGGGGATCTAACTGGCAACCAAAGGTTGCACCAACAACCGCTTGGAATGCTGCAACAATGCCTC
CACAAATGGGAAGTGTTCCTGTAATGACGCAACCAACCTTAATATACAGCCAGCCTGTCATGAGACCTCCAAACCCCTTTGGCCCTGTAT

>In-frame_ENST00000308580_ENST00000356360_TCGA-06-0878-01A_TMOD3_chr15_52194233_+_PICALM_chr11_85722179_length(amino acids)=757AA_start in transcript=272_stop in transcript=2545
MHIMALPFRKDLEKYKDLDEDELLGNLSETELKQLETVLDDLDPENALLPAGFRQKNQTSKSTTGPFDREHLLSYLEKEALEHKDREDYV
PYTGEKKGKIFIPKQKPVQTFTEEKVSLDPELEEALTSASDTELCDLAAILGMHNLITNTKFCNIMGSSNGVDQEHFSNVVKGEKILPVF
DEPPNPTNVEESLKRTKENDAHLVEVNLNNIKNIPIPTLKDFAKALETNTHVKCFSLAATRSNDPVATAFAEMLKVNKTLKSLNVESNFI
TGVGILALIDALRDNETLAELKIDNQRQQLGTAVELEMAKMLEENTNILKFGYQFTQQGPRTRAANAITKNNDLEKYFDMKKNQCKEGLD
IYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQ
AALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVA
STWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTRTPTHEMFVGFTPSPVAQPHPSAGLNVDFESVFGNKSTNVIVDSG
GFDELGGLLKPTVASQNQNLPVAKLPPSKLVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMPP

--------------------------------------------------------------
>In-frame_ENST00000544199_ENST00000532317_TCGA-06-0878-01A_TMOD3_chr15_52194233_+_PICALM_chr11_85722179_length(transcript)=3608nt_BP=1071nt
GACTGTACTGAACAGCAAAAATTAAGTGACTTGCTGCCCTGCACATCATGGCACTGCCATTCCGTAAGGACTTAGAAAAGTACAAAGACC
TTGATGAAGATGAGCTCCTTGGGAATCTGTCAGAAACAGAACTGAAACAACTGGAAACTGTTTTGGATGATCTTGACCCCGAGAATGCCC
TTCTGCCTGCAGGGTTCCGGCAGAAGAACCAGACATCAAAGTCCACCACAGGGCCATTTGATAGAGAGCATCTCCTTTCATATCTGGAGA
AAGAAGCATTGGAGCATAAAGACAGGGAAGACTATGTGCCCTACACTGGAGAAAAAAAAGGGAAAATATTTATCCCCAAACAGAAACCTG
TACAGACTTTTACAGAAGAAAAAGTGTCTCTTGATCCAGAATTAGAAGAAGCTTTGACAAGTGCTTCTGATACAGAATTGTGTGACCTCG
CAGCAATTCTTGGGATGCACAATTTGATAACGAATACAAAGTTCTGTAATATAATGGGAAGTAGTAATGGTGTTGACCAAGAACATTTTT
CAAATGTGGTCAAAGGTGAAAAGATTCTTCCGGTATTTGATGAGCCACCAAATCCAACCAATGTAGAAGAGAGTTTGAAGAGAACTAAAG
AAAACGATGCTCATCTTGTTGAAGTTAATTTGAATAATATAAAGAATATCCCAATTCCAACCCTAAAAGATTTTGCAAAGGCTTTGGAAA
CCAACACACATGTGAAATGTTTCAGTCTTGCAGCCACCCGGAGCAATGACCCTGTTGCTACTGCTTTTGCAGAAATGCTGAAAGTGAACA
AAACTTTGAAGAGCTTAAATGTGGAGTCCAACTTTATCACGGGAGTTGGGATTCTGGCACTGATTGATGCGTTAAGAGATAATGAAACCC
TGGCAGAGCTCAAGATTGACAATCAGAGGCAGCAGTTGGGGACAGCTGTAGAATTGGAAATGGCCAAGATGCTTGAGGAAAATACAAATA
TCCTTAAATTTGGATATCAGTTTACACAGCAGGGACCACGAACCAGAGCAGCTAATGCTATAACAAAAAACAATGACTTAGAAAAATATT
TTGATATGAAAAAGAACCAATGCAAAGAAGGTCTTGACATCTATAAGAAGTTCCTAACTAGGATGACAAGAATCTCAGAGTTCCTCAAAG
TTGCAGAGCAAGTTGGAATTGACAGAGGTGATATACCAGACCTTTCACAGGCCCCTAGCAGTCTTCTTGATGCTTTGGAACAACATTTAG
CTTCCTTGGAAGGAAAGAAAATCAAAGATTCTACAGCTGCAAGCAGGGCAACTACACTTTCCAATGCAGTGTCTTCCCTGGCAAGCACTG
GTCTATCTCTGACCAAAGTGGATGAAAGGGAAAAGCAGGCAGCATTAGAGGAAGAACAGGCACGTTTGAAAGCTTTAAAGGAACAGCGCC
TAAAAGAACTTGCAAAGAAACCTCATACCTCTTTAACAACTGCAGCCTCTCCTGTATCCACCTCAGCAGGAGGGATAATGACTGCACCAG
CCATTGACATATTTTCTACCCCTAGTTCTTCTAACAGCACATCAAAGCTGCCCAATGATCTGCTTGATTTGCAGCAGCCAACTTTTCACC
CATCTGTACATCCTATGTCAACTGCTTCTCAGGTAGCAAGTACATGGGGAGGATTCACTCCTTCTCCAGTTGCACAGCCACACCCTTCAG
CTGGCCTTAATGTTGACTTTGAATCTGTGTTTGGAAATAAATCTACAAATGTTATTGTAGATTCTGGGGGCTTTGATGAACTAGGTGGAC
TTCTCAAACCAACAGTGGCCTCTCAGAACCAGAACCTTCCTGTTGCCAAACTCCCACCTAGCAAGTTAGTATCTGATGACTTGGATTCAT
CTTTAGCCAACCTTGTGGGCAATCTTGGCATCGGAAATGGAACCACTAAGAATGATGTAAATTGGAGTCAACCAGGTGAAAAGAAGTTAA
CTGGGGGATCTAACTGGCAACCAAAGGTTGCACCAACAACCGCTTGGAATGCTGCAACAATGAATGGCATGCATTTTCCACAATACGCAC
CCCCTGTAATGGCCTATCCTGCTACTACACCAACAGGCATGATAGGATATGGAATTCCTCCACAAATGGGAAGTGTTCCTGTAATGACGC
AACCAACCTTAATATACAGCCAGCCTGTCATGAGACCTCCAAACCCCTTTGGCCCTGTATCAGGAGCACAGATACAGTTTATGTAACTTG
ATGGAAGAAAATGGAATTACTCCAAAAAGACAAGTGCTCAAGCAGCAAAATCCTTACTTCCAGCAAAATCCAAACTGCTGTCTCTTAAAT
CTCTTAAACTCTCTTCTTCCATTAGAATGCTACAAGTAACTCAGTGAAGGCCCATGAAGGAAATTGGGACTAGTTTATAGGAGAACGTAT
CAATACAGTTTATAAAGCCAAGAATTGCTATGATTTAAGACTAAGATCTGTCTTTTTGGTGACTAACCCTTCAATTCTTTCAACTCCTGT
TAATACCCATAATCAGTAACCTATCAAGAAAAGCCCTTATTTGGAAAGTGTGAAATTTGTATTTGGAAAAGCTGCCTGGAGAGAAGAACT
GTGTCCTTTACTGTATTTCAACAGGACTCTTTTGGGGGATCAAAATTAAAATTCCTAATTATGCATTATCTTTCTTTTCTCCAGTCCTCA
CAAATACAGAAACAATAACTGAAATTAACTTTTCTTTTTTTAAAAAAAATTATATTCAGTTTGCAGTAGACATTCCTTAAGTATTTGTAT
TTATTTATGATTATCAATTTTACATAACATTAATATTGTATCAGACCTCCTTATGAAAATGAGTATGGATGTGCACAGTATGTTTGATTT
TTATCCACAAGAATGAATCTGATTCAGAATGCTTTTCTCAGCTGACATACAGAGCACTAAATATTTTAAGGCAAGTCCATAGGTCTGAAT
CTCTTAAGAATTCTCGGCCTCTGTGGGATTTAGGGAAGCATTATAAATGCATTAATCCTTATAGTCAATTCTGTGCCTAGGATTTTGCCA
GGGAACAGTTCACTGACTAGGAAAAGCACTACATTTTAAATTCAGCATTAGTGCATTGGGAAGGATCTTTACTGCTTTGTGCTTGGCATG
TCATTATTTTCCATTTGACATTAGGGCCTTTCCAAAATGAATGTGAGGAATTGCTTTCACTTCAAGACTTTCCTTCTTTTCACTAAAACT
CTAGAAGGTGTTACAAGGGGGAGGGAAGGGGGGCAAAGTCCTTGAACATTTTCTTTGGCTCGTGCCATGTTATGATCATATACCTTTTAA
ATAAGGGGAAATAGTATCTTTAAAGTTAATGTCTAGCCAAGAGTTTAGTAAACGAAGAATTAAACTGCACTGTTGATCGGTGCTTTGTGT
AAATACATCTTTAACATTTGGGTGGAGAGGGGCCTTAAGAAGGACAGTTCATTGTAGGAAAGCAATTCTGTACATGAGTTTAAGCATTCT
TGTTGCATTGTCTCTGCAGATTCTATTTTTGTTTACAATATTAAAATGTATGTTAGCAAAATGGGTGGATTTTCAAATAAAATGCAGCTT

>In-frame_ENST00000544199_ENST00000532317_TCGA-06-0878-01A_TMOD3_chr15_52194233_+_PICALM_chr11_85722179_length(amino acids)=735AA_start in transcript=38_stop in transcript=2245
MHIMALPFRKDLEKYKDLDEDELLGNLSETELKQLETVLDDLDPENALLPAGFRQKNQTSKSTTGPFDREHLLSYLEKEALEHKDREDYV
PYTGEKKGKIFIPKQKPVQTFTEEKVSLDPELEEALTSASDTELCDLAAILGMHNLITNTKFCNIMGSSNGVDQEHFSNVVKGEKILPVF
DEPPNPTNVEESLKRTKENDAHLVEVNLNNIKNIPIPTLKDFAKALETNTHVKCFSLAATRSNDPVATAFAEMLKVNKTLKSLNVESNFI
TGVGILALIDALRDNETLAELKIDNQRQQLGTAVELEMAKMLEENTNILKFGYQFTQQGPRTRAANAITKNNDLEKYFDMKKNQCKEGLD
IYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQ
AALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVA
STWGGFTPSPVAQPHPSAGLNVDFESVFGNKSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKLPPSKLVSDDLDSSLANLVGNLGIGN
GTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMNGMHFPQYAPPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPTLIYSQPVMRP

--------------------------------------------------------------
>In-frame_ENST00000544199_ENST00000526033_TCGA-06-0878-01A_TMOD3_chr15_52194233_+_PICALM_chr11_85722179_length(transcript)=3709nt_BP=1071nt
GACTGTACTGAACAGCAAAAATTAAGTGACTTGCTGCCCTGCACATCATGGCACTGCCATTCCGTAAGGACTTAGAAAAGTACAAAGACC
TTGATGAAGATGAGCTCCTTGGGAATCTGTCAGAAACAGAACTGAAACAACTGGAAACTGTTTTGGATGATCTTGACCCCGAGAATGCCC
TTCTGCCTGCAGGGTTCCGGCAGAAGAACCAGACATCAAAGTCCACCACAGGGCCATTTGATAGAGAGCATCTCCTTTCATATCTGGAGA
AAGAAGCATTGGAGCATAAAGACAGGGAAGACTATGTGCCCTACACTGGAGAAAAAAAAGGGAAAATATTTATCCCCAAACAGAAACCTG
TACAGACTTTTACAGAAGAAAAAGTGTCTCTTGATCCAGAATTAGAAGAAGCTTTGACAAGTGCTTCTGATACAGAATTGTGTGACCTCG
CAGCAATTCTTGGGATGCACAATTTGATAACGAATACAAAGTTCTGTAATATAATGGGAAGTAGTAATGGTGTTGACCAAGAACATTTTT
CAAATGTGGTCAAAGGTGAAAAGATTCTTCCGGTATTTGATGAGCCACCAAATCCAACCAATGTAGAAGAGAGTTTGAAGAGAACTAAAG
AAAACGATGCTCATCTTGTTGAAGTTAATTTGAATAATATAAAGAATATCCCAATTCCAACCCTAAAAGATTTTGCAAAGGCTTTGGAAA
CCAACACACATGTGAAATGTTTCAGTCTTGCAGCCACCCGGAGCAATGACCCTGTTGCTACTGCTTTTGCAGAAATGCTGAAAGTGAACA
AAACTTTGAAGAGCTTAAATGTGGAGTCCAACTTTATCACGGGAGTTGGGATTCTGGCACTGATTGATGCGTTAAGAGATAATGAAACCC
TGGCAGAGCTCAAGATTGACAATCAGAGGCAGCAGTTGGGGACAGCTGTAGAATTGGAAATGGCCAAGATGCTTGAGGAAAATACAAATA
TCCTTAAATTTGGATATCAGTTTACACAGCAGGGACCACGAACCAGAGCAGCTAATGCTATAACAAAAAACAATGACTTAGAAAAATATT
TTGATATGAAAAAGAACCAATGCAAAGAAGGTCTTGACATCTATAAGAAGTTCCTAACTAGGATGACAAGAATCTCAGAGTTCCTCAAAG
TTGCAGAGCAAGTTGGAATTGACAGAGGTGATATACCAGACCTTTCACAGGCCCCTAGCAGTCTTCTTGATGCTTTGGAACAACATTTAG
CTTCCTTGGAAGGAAAGAAAATCAAAGATTCTACAGCTGCAAGCAGGGCAACTACACTTTCCAATGCAGTGTCTTCCCTGGCAAGCACTG
GTCTATCTCTGACCAAAGTGGATGAAAGGGAAAAGCAGGCAGCATTAGAGGAAGAACAGGCACGTTTGAAAGCTTTAAAGGAACAGCGCC
TAAAAGAACTTGCAAAGAAACCTCATACCTCTTTAACAACTGCAGCCTCTCCTGTATCCACCTCAGCAGGAGGGATAATGACTGCACCAG
CCATTGACATATTTTCTACCCCTAGTTCTTCTAACAGCACATCAAAGCTGCCCAATGATCTGCTTGATTTGCAGCAGCCAACTTTTCACC
CATCTGTACATCCTATGTCAACTGCTTCTCAGGTAGCAAGTACATGGGGAGATGCTGTTGATGATGCCATTCCAAGCTTAAATCCTTTCC
TCACAAAAAGTAGTGGTGATGTTCACCTTTCCATTTCTTCAGATGTATCTACTTTTACTACTAGGACACCTACTCATGAAATGTTTGTTG
GATTCACTCCTTCTCCAGTTGCACAGCCACACCCTTCAGCTGGCCTTAATGTTGACTTTGAATCTGTGTTTGGAAATAAATCTACAAATG
TTATTGTAGATTCTGGGGGCTTTGATGAACTAGGTGGACTTCTCAAACCAACAGTGGCCTCTCAGAACCAGAACCTTCCTGTTGCCAAAC
TCCCACCTAGCAAGTTAGTATCTGATGACTTGGATTCATCTTTAGCCAACCTTGTGGGCAATCTTGGCATCGGAAATGGAACCACTAAGA
ATGATGTAAATTGGAGTCAACCAGGTGAAAAGAAGTTAACTGGGGGATCTAACTGGCAACCAAAGGTTGCACCAACAACCGCTTGGAATG
CTGCAACAATGGCACCCCCTGTAATGGCCTATCCTGCTACTACACCAACAGGCATGATAGGATATGGAATTCCTCCACAAATGGGAAGTG
TTCCTGTAATGACGCAACCAACCTTAATATACAGCCAGCCTGTCATGAGACCTCCAAACCCCTTTGGCCCTGTATCAGGAGCACAGATAC
AGTTTATGTAACTTGATGGAAGAAAATGGAATTACTCCAAAAAGACAAGTGCTCAAGCAGCAAAATCCTTACTTCCAGCAAAATCCAAAC
TGCTGTCTCTTAAATCTCTTAAACTCTCTTCTTCCATTAGAATGCTACAAGTAACTCAGTGAAGGCCCATGAAGGAAATTGGGACTAGTT
TATAGGAGAACGTATCAATACAGTTTATAAAGCCAAGAATTGCTATGATTTAAGACTAAGATCTGTCTTTTTGGTGACTAACCCTTCAAT
TCTTTCAACTCCTGTTAATACCCATAATCAGTAACCTATCAAGAAAAGCCCTTATTTGGAAAGTGTGAAATTTGTATTTGGAAAAGCTGC
CTGGAGAGAAGAACTGTGTCCTTTACTGTATTTCAACAGGACTCTTTTGGGGGATCAAAATTAAAATTCCTAATTATGCATTATCTTTCT
TTTCTCCAGTCCTCACAAATACAGAAACAATAACTGAAATTAACTTTTCTTTTTTTAAAAAAAATTATATTCAGTTTGCAGTAGACATTC
CTTAAGTATTTGTATTTATTTATGATTATCAATTTTACATAACATTAATATTGTATCAGACCTCCTTATGAAAATGAGTATGGATGTGCA
CAGTATGTTTGATTTTTATCCACAAGAATGAATCTGATTCAGAATGCTTTTCTCAGCTGACATACAGAGCACTAAATATTTTAAGGCAAG
TCCATAGGTCTGAATCTCTTAAGAATTCTCGGCCTCTGTGGGATTTAGGGAAGCATTATAAATGCATTAATCCTTATAGTCAATTCTGTG
CCTAGGATTTTGCCAGGGAACAGTTCACTGACTAGGAAAAGCACTACATTTTAAATTCAGCATTAGTGCATTGGGAAGGATCTTTACTGC
TTTGTGCTTGGCATGTCATTATTTTCCATTTGACATTAGGGCCTTTCCAAAATGAATGTGAGGAATTGCTTTCACTTCAAGACTTTCCTT
CTTTTCACTAAAACTCTAGAAGGTGTTACAAGGGGGAGGGAAGGGGGGCAAAGTCCTTGAACATTTTCTTTGGCTCGTGCCATGTTATGA
TCATATACCTTTTAAATAAGGGGAAATAGTATCTTTAAAGTTAATGTCTAGCCAAGAGTTTAGTAAACGAAGAATTAAACTGCACTGTTG
ATCGGTGCTTTGTGTAAATACATCTTTAACATTTGGGTGGAGAGGGGCCTTAAGAAGGACAGTTCATTGTAGGAAAGCAATTCTGTACAT
GAGTTTAAGCATTCTTGTTGCATTGTCTCTGCAGATTCTATTTTTGTTTACAATATTAAAATGTATGTTAGCAAAATGGGTGGATTTTCA

>In-frame_ENST00000544199_ENST00000526033_TCGA-06-0878-01A_TMOD3_chr15_52194233_+_PICALM_chr11_85722179_length(amino acids)=770AA_start in transcript=38_stop in transcript=2350
MHIMALPFRKDLEKYKDLDEDELLGNLSETELKQLETVLDDLDPENALLPAGFRQKNQTSKSTTGPFDREHLLSYLEKEALEHKDREDYV
PYTGEKKGKIFIPKQKPVQTFTEEKVSLDPELEEALTSASDTELCDLAAILGMHNLITNTKFCNIMGSSNGVDQEHFSNVVKGEKILPVF
DEPPNPTNVEESLKRTKENDAHLVEVNLNNIKNIPIPTLKDFAKALETNTHVKCFSLAATRSNDPVATAFAEMLKVNKTLKSLNVESNFI
TGVGILALIDALRDNETLAELKIDNQRQQLGTAVELEMAKMLEENTNILKFGYQFTQQGPRTRAANAITKNNDLEKYFDMKKNQCKEGLD
IYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQ
AALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVA
STWGDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTRTPTHEMFVGFTPSPVAQPHPSAGLNVDFESVFGNKSTNVIVDSGGFDELGG
LLKPTVASQNQNLPVAKLPPSKLVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMAPPVMAYPA

--------------------------------------------------------------
>In-frame_ENST00000544199_ENST00000393346_TCGA-06-0878-01A_TMOD3_chr15_52194233_+_PICALM_chr11_85722179_length(transcript)=2604nt_BP=1071nt
GACTGTACTGAACAGCAAAAATTAAGTGACTTGCTGCCCTGCACATCATGGCACTGCCATTCCGTAAGGACTTAGAAAAGTACAAAGACC
TTGATGAAGATGAGCTCCTTGGGAATCTGTCAGAAACAGAACTGAAACAACTGGAAACTGTTTTGGATGATCTTGACCCCGAGAATGCCC
TTCTGCCTGCAGGGTTCCGGCAGAAGAACCAGACATCAAAGTCCACCACAGGGCCATTTGATAGAGAGCATCTCCTTTCATATCTGGAGA
AAGAAGCATTGGAGCATAAAGACAGGGAAGACTATGTGCCCTACACTGGAGAAAAAAAAGGGAAAATATTTATCCCCAAACAGAAACCTG
TACAGACTTTTACAGAAGAAAAAGTGTCTCTTGATCCAGAATTAGAAGAAGCTTTGACAAGTGCTTCTGATACAGAATTGTGTGACCTCG
CAGCAATTCTTGGGATGCACAATTTGATAACGAATACAAAGTTCTGTAATATAATGGGAAGTAGTAATGGTGTTGACCAAGAACATTTTT
CAAATGTGGTCAAAGGTGAAAAGATTCTTCCGGTATTTGATGAGCCACCAAATCCAACCAATGTAGAAGAGAGTTTGAAGAGAACTAAAG
AAAACGATGCTCATCTTGTTGAAGTTAATTTGAATAATATAAAGAATATCCCAATTCCAACCCTAAAAGATTTTGCAAAGGCTTTGGAAA
CCAACACACATGTGAAATGTTTCAGTCTTGCAGCCACCCGGAGCAATGACCCTGTTGCTACTGCTTTTGCAGAAATGCTGAAAGTGAACA
AAACTTTGAAGAGCTTAAATGTGGAGTCCAACTTTATCACGGGAGTTGGGATTCTGGCACTGATTGATGCGTTAAGAGATAATGAAACCC
TGGCAGAGCTCAAGATTGACAATCAGAGGCAGCAGTTGGGGACAGCTGTAGAATTGGAAATGGCCAAGATGCTTGAGGAAAATACAAATA
TCCTTAAATTTGGATATCAGTTTACACAGCAGGGACCACGAACCAGAGCAGCTAATGCTATAACAAAAAACAATGACTTAGAAAAATATT
TTGATATGAAAAAGAACCAATGCAAAGAAGGTCTTGACATCTATAAGAAGTTCCTAACTAGGATGACAAGAATCTCAGAGTTCCTCAAAG
TTGCAGAGCAAGTTGGAATTGACAGAGGTGATATACCAGACCTTTCACAGGCCCCTAGCAGTCTTCTTGATGCTTTGGAACAACATTTAG
CTTCCTTGGAAGGAAAGAAAATCAAAGATTCTACAGCTGCAAGCAGGGCAACTACACTTTCCAATGCAGTGTCTTCCCTGGCAAGCACTG
GTCTATCTCTGACCAAAGTGGATGAAAGGGAAAAGCAGGCAGCATTAGAGGAAGAACAGGCACGTTTGAAAGCTTTAAAGGAACAGCGCC
TAAAAGAACTTGCAAAGAAACCTCATACCTCTTTAACAACTGCAGCCTCTCCTGTATCCACCTCAGCAGGAGGGATAATGACTGCACCAG
CCATTGACATATTTTCTACCCCTAGTTCTTCTAACAGCACATCAAAGCTGCCCAATGATCTGCTTGATTTGCAGCAGCCAACTTTTCACC
CATCTGTACATCCTATGTCAACTGCTTCTCAGGTAGCAAGTACATGGGGAGATCCTTTCTCTGCTACTGTAGATGCTGTTGATGATGCCA
TTCCAAGCTTAAATCCTTTCCTCACAAAAAGTAGTGGTGATGTTCACCTTTCCATTTCTTCAGATGTATCTACTTTTACTACTAGGACAC
CTACTCATGAAATGTTTGTTGGATTCACTCCTTCTCCAGTTGCACAGCCACACCCTTCAGCTGGCCTTAATGTTGACTTTGAATCTGTGT
TTGGAAATAAATCTACAAATGTTATTGTAGATTCTGGGGGCTTTGATGAACTAGGTGGACTTCTCAAACCAACAGTGGCCTCTCAGAACC
AGAACCTTCCTGTTGCCAAACTCCCACCTAGCAAGTTAGTATCTGATGACTTGGATTCATCTTTAGCCAACCTTGTGGGCAATCTTGGCA
TCGGAAATGGAACCACTAAGAATGATGTAAATTGGAGTCAACCAGGTGAAAAGAAGTTAACTGGGGGATCTAACTGGCAACCAAAGGTTG
CACCAACAACCGCTTGGAATGCTGCAACAATGGCACCCCCTGTAATGGCCTATCCTGCTACTACACCAACAGGCATGATAGGATATGGAA
TTCCTCCACAAATGGGAAGTGTTCCTGTAATGACGCAACCAACCTTAATATACAGCCAGCCTGTCATGAGACCTCCAAACCCCTTTGGCC
CTGTATCAGGAGCACAGATACAGTTTATGTAACTTGATGGAAGAAAATGGAATTACTCCAAAAAGACAAGTGCTCAAGCAGCAAAATCCT
TACTTCCAGCAAAATCCAAACTGCTGTCTCTTAAATCTCTTAAACTCTCTTCTTCCATTAGAATGCTACAAGTAACTCAGTGAAGGCCCA

>In-frame_ENST00000544199_ENST00000393346_TCGA-06-0878-01A_TMOD3_chr15_52194233_+_PICALM_chr11_85722179_length(amino acids)=777AA_start in transcript=38_stop in transcript=2371
MHIMALPFRKDLEKYKDLDEDELLGNLSETELKQLETVLDDLDPENALLPAGFRQKNQTSKSTTGPFDREHLLSYLEKEALEHKDREDYV
PYTGEKKGKIFIPKQKPVQTFTEEKVSLDPELEEALTSASDTELCDLAAILGMHNLITNTKFCNIMGSSNGVDQEHFSNVVKGEKILPVF
DEPPNPTNVEESLKRTKENDAHLVEVNLNNIKNIPIPTLKDFAKALETNTHVKCFSLAATRSNDPVATAFAEMLKVNKTLKSLNVESNFI
TGVGILALIDALRDNETLAELKIDNQRQQLGTAVELEMAKMLEENTNILKFGYQFTQQGPRTRAANAITKNNDLEKYFDMKKNQCKEGLD
IYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQ
AALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVA
STWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTRTPTHEMFVGFTPSPVAQPHPSAGLNVDFESVFGNKSTNVIVDSG
GFDELGGLLKPTVASQNQNLPVAKLPPSKLVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMAP

--------------------------------------------------------------
>In-frame_ENST00000544199_ENST00000528398_TCGA-06-0878-01A_TMOD3_chr15_52194233_+_PICALM_chr11_85722179_length(transcript)=2429nt_BP=1071nt
GACTGTACTGAACAGCAAAAATTAAGTGACTTGCTGCCCTGCACATCATGGCACTGCCATTCCGTAAGGACTTAGAAAAGTACAAAGACC
TTGATGAAGATGAGCTCCTTGGGAATCTGTCAGAAACAGAACTGAAACAACTGGAAACTGTTTTGGATGATCTTGACCCCGAGAATGCCC
TTCTGCCTGCAGGGTTCCGGCAGAAGAACCAGACATCAAAGTCCACCACAGGGCCATTTGATAGAGAGCATCTCCTTTCATATCTGGAGA
AAGAAGCATTGGAGCATAAAGACAGGGAAGACTATGTGCCCTACACTGGAGAAAAAAAAGGGAAAATATTTATCCCCAAACAGAAACCTG
TACAGACTTTTACAGAAGAAAAAGTGTCTCTTGATCCAGAATTAGAAGAAGCTTTGACAAGTGCTTCTGATACAGAATTGTGTGACCTCG
CAGCAATTCTTGGGATGCACAATTTGATAACGAATACAAAGTTCTGTAATATAATGGGAAGTAGTAATGGTGTTGACCAAGAACATTTTT
CAAATGTGGTCAAAGGTGAAAAGATTCTTCCGGTATTTGATGAGCCACCAAATCCAACCAATGTAGAAGAGAGTTTGAAGAGAACTAAAG
AAAACGATGCTCATCTTGTTGAAGTTAATTTGAATAATATAAAGAATATCCCAATTCCAACCCTAAAAGATTTTGCAAAGGCTTTGGAAA
CCAACACACATGTGAAATGTTTCAGTCTTGCAGCCACCCGGAGCAATGACCCTGTTGCTACTGCTTTTGCAGAAATGCTGAAAGTGAACA
AAACTTTGAAGAGCTTAAATGTGGAGTCCAACTTTATCACGGGAGTTGGGATTCTGGCACTGATTGATGCGTTAAGAGATAATGAAACCC
TGGCAGAGCTCAAGATTGACAATCAGAGGCAGCAGTTGGGGACAGCTGTAGAATTGGAAATGGCCAAGATGCTTGAGGAAAATACAAATA
TCCTTAAATTTGGATATCAGTTTACACAGCAGGGACCACGAACCAGAGCAGCTAATGCTATAACAAAAAACAATGACTTAGAAAAATATT
TTGATATGAAAAAGAACCAATGCAAAGAAGGTCTTGACATCTATAAGAAGTTCCTAACTAGGATGACAAGAATCTCAGAGTTCCTCAAAG
TTGCAGAGCAAGTTGGAATTGACAGAGGTGATATACCAGACCTTTCACAGGCCCCTAGCAGTCTTCTTGATGCTTTGGAACAACATTTAG
CTTCCTTGGAAGGAAAGAAAATCAAAGATTCTACAGCTGCAAGCAGGGCAACTACACTTTCCAATGCAGTGTCTTCCCTGGCAAGCACTG
GTCTATCTCTGACCAAAGTGGATGAAAGGGAAAAGCAGGCAGCATTAGAGGAAGAACAGGCACGTTTGAAAGCTTTAAAGGAACAGCGCC
TAAAAGAACTTGCAAAGAAACCTCATACCTCTTTAACAACTGCAGCCTCTCCTGTATCCACCTCAGCAGGAGGGATAATGACTGCACCAG
CCATTGACATATTTTCTACCCCTAGTTCTTCTAACAGCACATCAAAGCTGCCCAATGATCTGCTTGATTTGCAGCAGCCAACTTTTCACC
CATCTGTACATCCTATGTCAACTGCTTCTCAGGTAGCAAGTACATGGGGAGGATTCACTCCTTCTCCAGTTGCACAGCCACACCCTTCAG
CTGGCCTTAATGTTGACTTTGAATCTGTGTTTGGAAATAAATCTACAAATGTTATTGTAGATTCTGGGGGCTTTGATGAACTAGGTGGAC
TTCTCAAACCAACAGTGGCCTCTCAGAACCAGAACCTTCCTGTTGCCAAACTCCCACCTAGCAAGTTAGTATCTGATGACTTGGATTCAT
CTTTAGCCAACCTTGTGGGCAATCTTGGCATCGGAAATGGAACCACTAAGAATGATGTAAATTGGAGTCAACCAGGTGAAAAGAAGTTAA
CTGGGGGATCTAACTGGCAACCAAAGGTTGCACCAACAACCGCTTGGAATGCTGCAACAATGGCACCCCCTGTAATGGCCTATCCTGCTA
CTACACCAACAGGCATGATAGGATATGGAATTCCTCCACAAATGGGAAGTGTTCCTGTAATGACGCAACCAACCTTAATATACAGCCAGC
CTGTCATGAGACCTCCAAACCCCTTTGGCCCTGTATCAGGAGCACAGATACAGTTTATGTAACTTGATGGAAGAAAATGGAATTACTCCA
AAAAGACAAGTGCTCAAGCAGCAAAATCCTTACTTCCAGCAAAATCCAAACTGCTGTCTCTTAAATCTCTTAAACTCTCTTCTTCCATTA

>In-frame_ENST00000544199_ENST00000528398_TCGA-06-0878-01A_TMOD3_chr15_52194233_+_PICALM_chr11_85722179_length(amino acids)=727AA_start in transcript=38_stop in transcript=2221
MHIMALPFRKDLEKYKDLDEDELLGNLSETELKQLETVLDDLDPENALLPAGFRQKNQTSKSTTGPFDREHLLSYLEKEALEHKDREDYV
PYTGEKKGKIFIPKQKPVQTFTEEKVSLDPELEEALTSASDTELCDLAAILGMHNLITNTKFCNIMGSSNGVDQEHFSNVVKGEKILPVF
DEPPNPTNVEESLKRTKENDAHLVEVNLNNIKNIPIPTLKDFAKALETNTHVKCFSLAATRSNDPVATAFAEMLKVNKTLKSLNVESNFI
TGVGILALIDALRDNETLAELKIDNQRQQLGTAVELEMAKMLEENTNILKFGYQFTQQGPRTRAANAITKNNDLEKYFDMKKNQCKEGLD
IYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQ
AALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVA
STWGGFTPSPVAQPHPSAGLNVDFESVFGNKSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKLPPSKLVSDDLDSSLANLVGNLGIGN
GTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMAPPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFGPVS

--------------------------------------------------------------
>In-frame_ENST00000544199_ENST00000356360_TCGA-06-0878-01A_TMOD3_chr15_52194233_+_PICALM_chr11_85722179_length(transcript)=2371nt_BP=1071nt
GACTGTACTGAACAGCAAAAATTAAGTGACTTGCTGCCCTGCACATCATGGCACTGCCATTCCGTAAGGACTTAGAAAAGTACAAAGACC
TTGATGAAGATGAGCTCCTTGGGAATCTGTCAGAAACAGAACTGAAACAACTGGAAACTGTTTTGGATGATCTTGACCCCGAGAATGCCC
TTCTGCCTGCAGGGTTCCGGCAGAAGAACCAGACATCAAAGTCCACCACAGGGCCATTTGATAGAGAGCATCTCCTTTCATATCTGGAGA
AAGAAGCATTGGAGCATAAAGACAGGGAAGACTATGTGCCCTACACTGGAGAAAAAAAAGGGAAAATATTTATCCCCAAACAGAAACCTG
TACAGACTTTTACAGAAGAAAAAGTGTCTCTTGATCCAGAATTAGAAGAAGCTTTGACAAGTGCTTCTGATACAGAATTGTGTGACCTCG
CAGCAATTCTTGGGATGCACAATTTGATAACGAATACAAAGTTCTGTAATATAATGGGAAGTAGTAATGGTGTTGACCAAGAACATTTTT
CAAATGTGGTCAAAGGTGAAAAGATTCTTCCGGTATTTGATGAGCCACCAAATCCAACCAATGTAGAAGAGAGTTTGAAGAGAACTAAAG
AAAACGATGCTCATCTTGTTGAAGTTAATTTGAATAATATAAAGAATATCCCAATTCCAACCCTAAAAGATTTTGCAAAGGCTTTGGAAA
CCAACACACATGTGAAATGTTTCAGTCTTGCAGCCACCCGGAGCAATGACCCTGTTGCTACTGCTTTTGCAGAAATGCTGAAAGTGAACA
AAACTTTGAAGAGCTTAAATGTGGAGTCCAACTTTATCACGGGAGTTGGGATTCTGGCACTGATTGATGCGTTAAGAGATAATGAAACCC
TGGCAGAGCTCAAGATTGACAATCAGAGGCAGCAGTTGGGGACAGCTGTAGAATTGGAAATGGCCAAGATGCTTGAGGAAAATACAAATA
TCCTTAAATTTGGATATCAGTTTACACAGCAGGGACCACGAACCAGAGCAGCTAATGCTATAACAAAAAACAATGACTTAGAAAAATATT
TTGATATGAAAAAGAACCAATGCAAAGAAGGTCTTGACATCTATAAGAAGTTCCTAACTAGGATGACAAGAATCTCAGAGTTCCTCAAAG
TTGCAGAGCAAGTTGGAATTGACAGAGGTGATATACCAGACCTTTCACAGGCCCCTAGCAGTCTTCTTGATGCTTTGGAACAACATTTAG
CTTCCTTGGAAGGAAAGAAAATCAAAGATTCTACAGCTGCAAGCAGGGCAACTACACTTTCCAATGCAGTGTCTTCCCTGGCAAGCACTG
GTCTATCTCTGACCAAAGTGGATGAAAGGGAAAAGCAGGCAGCATTAGAGGAAGAACAGGCACGTTTGAAAGCTTTAAAGGAACAGCGCC
TAAAAGAACTTGCAAAGAAACCTCATACCTCTTTAACAACTGCAGCCTCTCCTGTATCCACCTCAGCAGGAGGGATAATGACTGCACCAG
CCATTGACATATTTTCTACCCCTAGTTCTTCTAACAGCACATCAAAGCTGCCCAATGATCTGCTTGATTTGCAGCAGCCAACTTTTCACC
CATCTGTACATCCTATGTCAACTGCTTCTCAGGTAGCAAGTACATGGGGAGATCCTTTCTCTGCTACTGTAGATGCTGTTGATGATGCCA
TTCCAAGCTTAAATCCTTTCCTCACAAAAAGTAGTGGTGATGTTCACCTTTCCATTTCTTCAGATGTATCTACTTTTACTACTAGGACAC
CTACTCATGAAATGTTTGTTGGATTCACTCCTTCTCCAGTTGCACAGCCACACCCTTCAGCTGGCCTTAATGTTGACTTTGAATCTGTGT
TTGGAAATAAATCTACAAATGTTATTGTAGATTCTGGGGGCTTTGATGAACTAGGTGGACTTCTCAAACCAACAGTGGCCTCTCAGAACC
AGAACCTTCCTGTTGCCAAACTCCCACCTAGCAAGTTAGTATCTGATGACTTGGATTCATCTTTAGCCAACCTTGTGGGCAATCTTGGCA
TCGGAAATGGAACCACTAAGAATGATGTAAATTGGAGTCAACCAGGTGAAAAGAAGTTAACTGGGGGATCTAACTGGCAACCAAAGGTTG
CACCAACAACCGCTTGGAATGCTGCAACAATGCCTCCACAAATGGGAAGTGTTCCTGTAATGACGCAACCAACCTTAATATACAGCCAGC
CTGTCATGAGACCTCCAAACCCCTTTGGCCCTGTATCAGGAGCACAGATACAGTTTATGTAACTTGATGGAAGAAAATGGAATTACTCCA

>In-frame_ENST00000544199_ENST00000356360_TCGA-06-0878-01A_TMOD3_chr15_52194233_+_PICALM_chr11_85722179_length(amino acids)=757AA_start in transcript=38_stop in transcript=2311
MHIMALPFRKDLEKYKDLDEDELLGNLSETELKQLETVLDDLDPENALLPAGFRQKNQTSKSTTGPFDREHLLSYLEKEALEHKDREDYV
PYTGEKKGKIFIPKQKPVQTFTEEKVSLDPELEEALTSASDTELCDLAAILGMHNLITNTKFCNIMGSSNGVDQEHFSNVVKGEKILPVF
DEPPNPTNVEESLKRTKENDAHLVEVNLNNIKNIPIPTLKDFAKALETNTHVKCFSLAATRSNDPVATAFAEMLKVNKTLKSLNVESNFI
TGVGILALIDALRDNETLAELKIDNQRQQLGTAVELEMAKMLEENTNILKFGYQFTQQGPRTRAANAITKNNDLEKYFDMKKNQCKEGLD
IYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQ
AALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVA
STWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTRTPTHEMFVGFTPSPVAQPHPSAGLNVDFESVFGNKSTNVIVDSG
GFDELGGLLKPTVASQNQNLPVAKLPPSKLVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMPP

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Fusion Gene PPI Analysis for TMOD3-PICALM


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgenePICALMchr15:52194233chr11:85722179ENST00000356360519221_294219.33333333333334633.0PIMREG
TgenePICALMchr15:52194233chr11:85722179ENST00000393346520221_294219.33333333333334653.0PIMREG
TgenePICALMchr15:52194233chr11:85722179ENST00000526033520221_294219.33333333333334646.0PIMREG
TgenePICALMchr15:52194233chr11:85722179ENST00000528398519221_294168.33333333333334552.0PIMREG
TgenePICALMchr15:52194233chr11:85722179ENST00000532317520221_294219.33333333333334611.0PIMREG


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TMOD3-PICALM


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TMOD3-PICALM


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgenePICALMC0002395Alzheimer's Disease2CTD_human
TgenePICALMC0011265Presenile dementia2CTD_human
TgenePICALMC0276496Familial Alzheimer Disease (FAD)2CTD_human
TgenePICALMC0494463Alzheimer Disease, Late Onset2CTD_human
TgenePICALMC0546126Acute Confusional Senile Dementia2CTD_human
TgenePICALMC0750900Alzheimer's Disease, Focal Onset2CTD_human
TgenePICALMC0750901Alzheimer Disease, Early Onset2CTD_human
TgenePICALMC0234985Mental deterioration1CTD_human
TgenePICALMC0338656Impaired cognition1CTD_human
TgenePICALMC1270972Mild cognitive disorder1CTD_human