|
||||||
|
 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:TRNAU1AP-NOL9 (FusionGDB2 ID:93670) |
Fusion Gene Summary for TRNAU1AP-NOL9 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TRNAU1AP-NOL9 | Fusion gene ID: 93670 | Hgene | Tgene | Gene symbol | TRNAU1AP | NOL9 | Gene ID | 54952 | 79707 |
| Gene name | tRNA selenocysteine 1 associated protein 1 | nucleolar protein 9 | |
| Synonyms | PRO1902|SECP43|TRSPAP1 | Grc3|NET6 | |
| Cytomap | 1p35.3 | 1p36.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | tRNA selenocysteine 1-associated protein 1tRNA selenocysteine associated protein (SECP43)tRNA selenocysteine-associated protein 1 | polynucleotide 5'-hydroxyl-kinase NOL9polynucleotide 5'-kinase | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | Q5SY16 | |
| Ensembl transtripts involved in fusion gene | ENST00000373830, ENST00000495995, | ENST00000377705, | |
| Fusion gene scores | * DoF score | 7 X 6 X 5=210 | 7 X 6 X 4=168 |
| # samples | 8 | 7 | |
| ** MAII score | log2(8/210*10)=-1.39231742277876 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(7/168*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: TRNAU1AP [Title/Abstract] AND NOL9 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | NOL9(6601890)-TRNAU1AP(28904012), # samples:2 TRNAU1AP(28898412)-NOL9(6593501), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | NOL9-TRNAU1AP seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. NOL9-TRNAU1AP seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across TRNAU1AP (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene breakpoints across NOL9 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | KIRC | TCGA-B0-5119-01A | TRNAU1AP | chr1 | 28898412 | + | NOL9 | chr1 | 6593501 | - |
Top |
Fusion Gene ORF analysis for TRNAU1AP-NOL9 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000373830 | ENST00000377705 | TRNAU1AP | chr1 | 28898412 | + | NOL9 | chr1 | 6593501 | - |
| intron-3CDS | ENST00000495995 | ENST00000377705 | TRNAU1AP | chr1 | 28898412 | + | NOL9 | chr1 | 6593501 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000373830 | TRNAU1AP | chr1 | 28898412 | + | ENST00000377705 | NOL9 | chr1 | 6593501 | - | 6294 | 753 | 26 | 1786 | 586 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000373830 | ENST00000377705 | TRNAU1AP | chr1 | 28898412 | + | NOL9 | chr1 | 6593501 | - | 0.001107425 | 0.9988926 |
Top |
Fusion Genomic Features for TRNAU1AP-NOL9 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
Top |
Fusion Protein Features for TRNAU1AP-NOL9 |
| Go to FGviewer for the breakpoints of chr1:28898412-chr1:6593501 - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. |
 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | NOL9 |
| FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes. | FUNCTION: Polynucleotide 5'-kinase involved in rRNA processing. The kinase activity is required for the processing of the 32S precursor into 5.8S and 28S rRNAs, more specifically for the generation of the major 5.8S(S) form. In vitro, has both DNA and RNA 5'-kinase activities. Probably binds RNA. {ECO:0000269|PubMed:21063389}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | TRNAU1AP | chr1:28898412 | chr1:6593501 | ENST00000373830 | + | 8 | 9 | 185_225 | 242.33333333333334 | 288.0 | Compositional bias | Note=Tyr-rich |
| Hgene | TRNAU1AP | chr1:28898412 | chr1:6593501 | ENST00000373830 | + | 8 | 9 | 3_86 | 242.33333333333334 | 288.0 | Domain | RRM 1 |
| Hgene | TRNAU1AP | chr1:28898412 | chr1:6593501 | ENST00000373830 | + | 8 | 9 | 96_175 | 242.33333333333334 | 288.0 | Domain | RRM 2 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | NOL9 | chr1:28898412 | chr1:6593501 | ENST00000377705 | 5 | 12 | 306_313 | 358.3333333333333 | 703.0 | Nucleotide binding | ATP |
Top |
Fusion Gene Sequence for TRNAU1AP-NOL9 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >In-frame_ENST00000373830_ENST00000377705_TCGA-B0-5119-01A_TRNAU1AP_chr1_28898412_+_NOL9_chr1_6593501_length(transcript)=6294nt_BP=753nt GCAAAGCCCCACCCCGGTGCGCGGGTATGGCGGCCAGCCTGTGGATGGGCGACCTGGAACCCTACATGGATGAGAACTTCATCTCCAGAG CCTTTGCCACCATGGGGGAGACCGTAATGAGCGTCAAAATTATCCGAAACCGCCTCACTGGGATCCCAGCTGGCTACTGCTTTGTAGAAT TTGCAGATTTGGCCACAGCTGAGAAGTGTTTGCATAAAATTAATGGGAAACCCCTTCCAGGAGCCACACCTGCGAAACGTTTTAAACTGA ACTATGCCACTTACGGGAAACAACCAGATAACAGCCCTGAGTATTCCCTCTTTGTGGGGGACCTGACCCCGGACGTGGATGATGGCATGC TGTATGAATTCTTCGTCAAAGTCTACCCCTCCTGTCGGGGAGGCAAGGTGGTTTTGGACCAGACAGGCGTGTCTAAGGGTTATGGTTTTG TGAAATTCACAGATGAACTGGAACAGAAGCGAGCCCTGACGGAGTGCCAGGGAGCAGTGGGACTGGGGTCTAAGCCTGTGCGGCTGAGCG TGGCAATCCCTAAAGCGAGCCGTGTAAAGCCAGTGGAATATAGTCAGATGTACAGTTATAGCTACAACCAGTATTATCAGCAGTACCAGA ACTACTATGCTCAGTGGGGCTATGACCAGAACACAGGCAGCTACAGCTACAGTTACCCCCAGTATGGCTATACCCAGAGCACCATGCAGA CATATGAAGAAGTTGGAGATGATGCATTGGAAGGACCACCTTTCACTCACCTGAGGACTCCACAGAAGATGGTATATTATGGGAAACCTT CTTGTAAAAACAACTATGAGAATTATATTGACATAGTGAAATATGTGTTCAGCGCTTACAAGAGAGAGTCCCCTCTCATCGTCAACACTA TGGGATGGGTTTCAGACCAGGGGCTCCTGCTTCTCATTGATCTGATCCGATTGCTGTCTCCCAGCCACGTGGTTCAGTTCCGCTCTGACC ACAGTAAATATATGCCAGACCTTACCCCGCAGTATGTAGATGACATGGATGGCTTGTACACAAAAAGCAAGACCAAGATGAGAAATCGAC GTTTCAGACTCGCAGCATTTGCAGATGCTTTGGAATTTGCTGATGAAGAAAAAGAGAGTCCAGTTGAGTTCACTGGACATAAACTGATAG GTGTTTATACAGACTTTGCATTCAGAATAACTCCAAGAAATAGAGAGTCACATAACAAAATTCTTCGAGATCTGTCCATCTTGAGTTACC TTAGCCAGCTGCAGCCCCCGATGCCCAAACCACTTTCTCCTTTACATAGCCTGACACCCTATCAGGTCCCTTTCAATGCAGTCGCACTCC GGATTACCCACTCTGATGTCGCCCCTACCCATATACTATATGCTGTAAACGCCAGCTGGGTTGGTCTTTGCAAGATCCAGGATGACGTCA GAGGATACACGAATGGGCCCATCCTGCTTGCCCAGACTCCAATCTGTGACTGCTTGGGCTTTGGCATCTGTAGAGGCATTGACATGGAGA AGCGGCTGTACCACATCCTCACCCCTGTGCCCCCGGAAGAGCTAAGGACCGTGAATTGTCTGCTCGTTGGAGCTATTGCCATTCCACATT GTGTCCTTAAGTGCCAGCGTGGGATCGAAGGGACAGTACCTTATGTCACAACGGATTACAATTTTAAACTTCCTGGAGCATCAGAGAAAA TTGGAGCAAGAGAACCTGAGGAGGCACATAAAGAGAAACCATACCGAAGACCTAAGTTCTGTCGAAAAATGAAGTGATGCTCGCGTTTTT AATAAGGGAAGAAACTTTCCTACCAGAAAGCTTTGTCTCAAGCCTGACCACAAGAGACATGATGGAGTTTCATGGCCATGAATGGTGCCC TTATTAGCAACAGTGTTTTTTGTGTAATTCGTGAATGTCATATAGTAGTCTTAAGTTTCTCTTTTAAAGCTGCATGAGCTAGAATTTGTT CTAGTCTTCTGTGTGATACTCATACTTGCTGTCCAGAGGGAGTAAAACAGCAGAGAACAGTTTGTGTGCCATTAAAACAGAGATTCCTCA GAAAGTTCTTCAGGGACCTGGTTATTAGAATCAGGATAAAAATAAGGAAACTGGGGCCATTACAATGTACCGAGAAGGAAGGAAGAAGGC CGACCTGCAGGATCTCAAGCATAATGGATACAAGGGCTCGCCACGGGCCTTGCCTGAGCCATGTGCAGAGCTGGGGTCCAGCGGTCTGCT TCCTTGGAGCCAGTGTGGATGGTTACAGCCCATCCATTTGGTGCAGTTGTACTTGGTCTGTTATATTCAATCAAGGTTTAATAGATAGGG CTGGGCATGGTGGCTCATGCACACCTGTAATCCTAGCACTTTGGGAGGCTGAGGCGGGAGGATTGCTTGAGCCTCGGAGTTCCAGGCTGG AGTACACCAACTACTCCAGCCTGAGCGACAGAGTAAGACCTTATCTTTTAAAAAAGAAAAGAAAAATTTAAACGGGTTTGATAGATATAA ATTTGGACCCAAGAGCCCTTCCTTTTTTTTAATCCTGAGGTTTTATGCTGAGGAAATTTCTTTCAAATCTGGAAAACCTCGGGGCCAGGC GCAGTGGCTCACGCCTGTAATTCCAGCACTTTGGGAGGCCAAGGCAGGCGGTTCACGAGGTCAGGAGATTGAGACCATCCTGGCTAACAC AGTGAAACTCCGTCTCTACTAAAAATACAAAAAACTAGCTGGGCGTGGTGGTGGGCGCCTATAGTCCCAGCTACTCAGGAGGCTGAGGCA GGAGAATGGCATGAACCCAGGAGGCGGAGCTTGCAGTGAGCCGAGGTCACGCCACTGCACTCCAGCCTGGGCAACAAGAGCAAGACTCCA TCTCAAAAAAAAAAAATAATAATCTGGAAAACCTCTTCTGGGGGCTCTTATAAAAGTAGATTTGTCCAAATTGACTTCTGATCTGAGGCC AGAGACAACCACAGGGCAGAGCTGGAGACTGGGCTGTTTTGAAGGAAGAAGGACTGGCAGACCAGCTCTTGGGAAAGCTCCATTATTGCC TGTGGGAGGCTGGACCTGAACTTGCACCTATGAACAACCCTGCCATTTAGAGCTTTTTCCTGGGGGTGCCGGCGGCTGGTGACCAGACTG CCATTCTCCACGTTCTCCCTGGTGCTTCCGACTCTGTCCTCTAGGTTGGAAGTGGTTTGTGTAAACGGGTGATGGGACCAGGTCACATCA TTTCTGCATTTAAGACAGCAGGATACTTCCTGGGGCTGAGGTTCAAACTGGTATTGTGACCACCGCTTTGACAGAATTCCATCTTCCCAG CATGATCACATTGTAAGACTATTAGGATGTGTGGGTTTTAACACTTATATACACTTATACAACTGTTGGTTATCATTGTCTTTAGTATTT TACAGTGGCCCCTCAGCACCTCTTAGACCCAACAGCAAAGGACTTAAAATAAGCACAGGAAACCTTGCTATGGTGATTAGTTTTGATACC TTTGAGACAATTGAGTCTAGCTTCTTAGTTGCCCCTTATTTATGTTGAAATCTGGCTCATTCATATGATGTTTTACTGTGCTGGCCTTGT AAAGAATTTTAAGACAATCCATCACCATCAATGTTTTGCCTTTCTCCACTTTCGTGTATCTTACAGTTATACTCACTGGAGGTCATTTGC AGCAAGGCTCTGGAAGAATGAAACTGGTGCCCTGTAATTGCATTTGCATTCAATCTAGGTTTGCCTTCAGGCTTTAAATGCGGCCTGTAT GAAGGTCAAGTCTTTTTCTTCAGTCCCTATCAGTAAAGAAAAATCGTTGCCTCTAGAGGGAGCTATCAGCTGTGGGTCAGGTGGCCGTAC TGGGGCTAGAGTTGGCCCAGGAAGCTGTACAGGGTTTAGGGAAGGAGGTTCGGAGACAGGGAGCCAAGGCCTCTGTCAGGTCTAGCTTGT GCCGGTCAGACCTGCAGCAGCACCATTCTCCAGGATGACAATTCATCCCATTATTGATGGCAGTGGCCTTTTTATCCTTTTTTTTTTTTT TTTTTTTTTTTGAGATGGAGTTTCGCTCTTGTTGCCCAGGCTGGAGTGCAGTGGCGCAATCTGGGCTCACTGCCACCTCCGCCTCCCGGG TTCAAGTGATTCTCTTGCCTCAACCTCCCGAGTAGCTGGGATTACAGGCATGCGCCACCATGCCTGGCTGATTTTCTATTTTTAGTAGAG AAGGGGTTTCACCATGTTGGCCAGGCTGGTTTTGAACTCCTGTCCTCAGGTGATCCACCTGCCTTGGCCTCCCAAAGTGTTGGGATTACA GGCATGAGCCACCGCACCCGGCTGGTGGCAGTGGCTTTAAGGGCATTTAGAAGAAGGACAAGATTGGACTTTTTATCATTTCCACAGTCT GTTATGGGTCAGATTAGGTAGTAAGGAGTTCTCCATTGGAGCTATTCTTTTTTTTTTTTCTTTTTTTTTGAGACAGAGTCTCGCTCTGTC ACCCAGGCTGGGGTGCAGTGGCACGACCTTGGCTCACTACAGCCTCTCCCCTCCCGGGTTCAAGTGATTCTTCTGCCCCAGCCTCCCAAG TAGCTGGGATTACAGGTGAGCGCCACCATGCCTGGCTAATTTTTATATTTTTAGTAGAGATAGGGTTTCACCGTATTGGCTAGGCTGGTC TCGATCTCCTGACCTTGTGATCCGCTTGCCTCGGCCTCCCAAAGTGCTGAAGCAATTTCTTTTTTTTTTTTTTTTTTGAGACAGAGTCTA GCTCTGTCGCCCAGGCTGGGGTGCAGTGGAGTGATCTCGGCTCACTGCAACTTCCGCCTCCCAGGTTTAAGCGATTCTCCTGCCTCAGCC TCCTGAGTAGCTGGGATTACAGGCGTATGCCACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGTCAG GCTGGTCTCGAACTCCTGACCTCGTGATCCGCCCGCCTTGGCCTCCGAAAGTGCTGGGATTACAGGCGTGAGCCACTGCGCCTGGCCTGA AGCTATTCTTTACAAAAGCTCTTAGTTTTTGTTTGTTTGTTTGTTTTTTTCTTTTGCGACGGACTCTCTGTCGCCAAGGCTGGAGTGCAG TGGCCTGATCTCAGGTCACTGCAACCTCTGCCTCCTGGGTTCAAGCGATTCTCCTGCTTCAGCCTCCCAAGTAGCTGGGATTACAGGCGC CTGCCACCACACCCAGCTAATTTTTGTATTTTTAGTAGAGATGGCGTTTCACTTTATTGGTCAGGCTGGTCTCGAACTTCCAACCTCAGG GGATCCGCCTGCCTTGGCCTCCCAAGGTGTTGGGATTACAGGCATAAGACACTGTGCCTGGGCCTCTTAGTAATTTTTGTATGTAATTTT CAAAGTATCCGGGATTACAGGCGCCCGCCACTACACTAGCTAATTTTTTTTGTATTTTTAGTAGAGATGGGGTTTTACTATGTTGGCTAG GCTGGTCTCGAGCTCCTGACCTCGTGATCCGTCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGCCTAG GTCATTTGTTTTTGGGTTTGGATGGCAAGATCATGGATAAGACAGCAGGCTTTGATTATAGAGCTCTGAGTTCAAATCCTGGCTCTACCA CTTGTCAGTGGTGTAACTTGGAGGAAGATGCTTAGCCTGAGCCTGTTTTATGTTTTGAAGATTGGGTAATTGTCCTTCCTTCAGTGTTCC TGGGTGAGGAGTAAGTGAAGTCATGTCTATAAGAGATGTAGCACAGTCTCCGGCATGTAGAAACGGTCAGTAACTCCTAGTGTGTAGCTA GCCTCTGATGAGATGGTAAACTCAGGAGGCTGGCACCACGGCTGTGCTACTCACGGTCATGCTGGAGGGATGCAGAAACTAAATGAATCC ACAGCTACTTACTCATCTTGCCTCTGGCAGGTTCACCTTAAAATTGTTGCTACCAAGCTTCCTGTGGTCAAAGAGCCCTTGAGGAAGCAA GCTCCACGGCCACCATAGATAACCCATTCCTGAAAGTTTTTCATAAACCCCCACTTGTTGCTTTTAAAATTTTATAAGCAGCTTACACAT GTAGAAAATGATCCTCCAGCCCACCACCACATAGTAATCACTGACACTGTGAGGTGTCTCAGCTGGGGTTCTGCTGTGTGTGTGTGTATT >In-frame_ENST00000373830_ENST00000377705_TCGA-B0-5119-01A_TRNAU1AP_chr1_28898412_+_NOL9_chr1_6593501_length(amino acids)=586AA_start in transcript=26_stop in transcript=1786 MAASLWMGDLEPYMDENFISRAFATMGETVMSVKIIRNRLTGIPAGYCFVEFADLATAEKCLHKINGKPLPGATPAKRFKLNYATYGKQP DNSPEYSLFVGDLTPDVDDGMLYEFFVKVYPSCRGGKVVLDQTGVSKGYGFVKFTDELEQKRALTECQGAVGLGSKPVRLSVAIPKASRV KPVEYSQMYSYSYNQYYQQYQNYYAQWGYDQNTGSYSYSYPQYGYTQSTMQTYEEVGDDALEGPPFTHLRTPQKMVYYGKPSCKNNYENY IDIVKYVFSAYKRESPLIVNTMGWVSDQGLLLLIDLIRLLSPSHVVQFRSDHSKYMPDLTPQYVDDMDGLYTKSKTKMRNRRFRLAAFAD ALEFADEEKESPVEFTGHKLIGVYTDFAFRITPRNRESHNKILRDLSILSYLSQLQPPMPKPLSPLHSLTPYQVPFNAVALRITHSDVAP THILYAVNASWVGLCKIQDDVRGYTNGPILLAQTPICDCLGFGICRGIDMEKRLYHILTPVPPEELRTVNCLLVGAIAIPHCVLKCQRGI -------------------------------------------------------------- |
Top |
Fusion Gene PPI Analysis for TRNAU1AP-NOL9 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
Related Drugs for TRNAU1AP-NOL9 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
Related Diseases for TRNAU1AP-NOL9 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2021-Present -The University of Texas Health Science Center at Houston (UTHealth)
Web File Viewing | Emergency Information |Campus Carry|Site Policies