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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
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Fusion gene:TTC13-JAK2 (FusionGDB2 ID:94248)

Fusion Gene Summary for TTC13-JAK2

Fusion gene summary

Fusion gene information	Fusion gene name: TTC13-JAK2
	Fusion gene ID: 94248
		Hgene	Tgene
	Gene symbol	TTC13	JAK2
	Gene ID	79573	3717
	Gene name	tetratricopeptide repeat domain 13	Janus kinase 2
	Synonyms	-	JTK10\|THCYT3
	Cytomap	1q42.2	9p24.1
	Type of gene	protein-coding	protein-coding
	Description	tetratricopeptide repeat protein 13TPR repeat protein 13epididymis secretory sperm binding protein	tyrosine-protein kinase JAK2JAK-2Janus kinase 2 (a protein tyrosine kinase)
	Modification date	20200313	20200329
	UniProtAcc	.	O60674
	Ensembl transtripts involved in fusion gene	ENST00000366661, ENST00000366662, ENST00000414259,	ENST00000539801, ENST00000381652, ENST00000544510, ENST00000487310,
Fusion gene scores	* DoF score	5 X 8 X 3=120	22 X 26 X 9=5148
	# samples	6	15
	** MAII score	log2(6/120*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(15/5148*10)=-5.10097764772482 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: TTC13 [Title/Abstract] AND JAK2 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	TTC13(231075132)-JAK2(5064883), # samples:3
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	JAK2	GO:0010811	positive regulation of cell-substrate adhesion	10925297
Tgene	JAK2	GO:0019221	cytokine-mediated signaling pathway	8609418
Tgene	JAK2	GO:0033209	tumor necrosis factor-mediated signaling pathway	8609418
Tgene	JAK2	GO:0034612	response to tumor necrosis factor	8609418
Tgene	JAK2	GO:0035409	histone H3-Y41 phosphorylation	19783980
Tgene	JAK2	GO:0035722	interleukin-12-mediated signaling pathway	7528775
Tgene	JAK2	GO:0046677	response to antibiotic	16280321
Tgene	JAK2	GO:0050727	regulation of inflammatory response	10925297
Tgene	JAK2	GO:0060396	growth hormone receptor signaling pathway	10925297
Tgene	JAK2	GO:0070671	response to interleukin-12	7528775

Fusion gene breakpoints across TTC13 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across JAK2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BRCA	TCGA-E9-A22D-01A	TTC13	chr1	231075132	-	JAK2	chr9	5064883	+
ChimerDB4	BRCA	TCGA-E9-A22D	TTC13	chr1	231075131	-	JAK2	chr9	5064882	+
ChimerDB4	BRCA	TCGA-E9-A22D-01A	TTC13	chr1	231075132	-	JAK2	chr9	5064883	+
ChimerDB4	BRCA	TCGA-E9-A22D-01A	TTC13	chr1	231079552	-	JAK2	chr9	5064883	+
ChimerDB4	BRCA	TCGA-E9-A22D-01A	TTC13	chr1	231090079	-	JAK2	chr9	5064883	+
ChimerDB4	BRCA	TCGA-E9-A22D-01A	TTC13	chr1	231075132	-	JAK2	chr9	5064883	+

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Fusion Gene ORF analysis for TTC13-JAK2

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
In-frame	ENST00000366661	ENST00000539801	TTC13	chr1	231075132	-	JAK2	chr9	5064883	+
In-frame	ENST00000366661	ENST00000381652	TTC13	chr1	231075132	-	JAK2	chr9	5064883	+
In-frame	ENST00000366661	ENST00000544510	TTC13	chr1	231075132	-	JAK2	chr9	5064883	+
5CDS-intron	ENST00000366661	ENST00000487310	TTC13	chr1	231075132	-	JAK2	chr9	5064883	+
In-frame	ENST00000366662	ENST00000539801	TTC13	chr1	231075132	-	JAK2	chr9	5064883	+
In-frame	ENST00000366662	ENST00000381652	TTC13	chr1	231075132	-	JAK2	chr9	5064883	+
In-frame	ENST00000366662	ENST00000544510	TTC13	chr1	231075132	-	JAK2	chr9	5064883	+
5CDS-intron	ENST00000366662	ENST00000487310	TTC13	chr1	231075132	-	JAK2	chr9	5064883	+
In-frame	ENST00000414259	ENST00000539801	TTC13	chr1	231075132	-	JAK2	chr9	5064883	+
In-frame	ENST00000414259	ENST00000381652	TTC13	chr1	231075132	-	JAK2	chr9	5064883	+
In-frame	ENST00000414259	ENST00000544510	TTC13	chr1	231075132	-	JAK2	chr9	5064883	+
5CDS-intron	ENST00000414259	ENST00000487310	TTC13	chr1	231075132	-	JAK2	chr9	5064883	+
In-frame	ENST00000366661	ENST00000539801	TTC13	chr1	231075131	-	JAK2	chr9	5064882	+
In-frame	ENST00000366661	ENST00000381652	TTC13	chr1	231075131	-	JAK2	chr9	5064882	+
In-frame	ENST00000366661	ENST00000544510	TTC13	chr1	231075131	-	JAK2	chr9	5064882	+
5CDS-intron	ENST00000366661	ENST00000487310	TTC13	chr1	231075131	-	JAK2	chr9	5064882	+
In-frame	ENST00000366662	ENST00000539801	TTC13	chr1	231075131	-	JAK2	chr9	5064882	+
In-frame	ENST00000366662	ENST00000381652	TTC13	chr1	231075131	-	JAK2	chr9	5064882	+
In-frame	ENST00000366662	ENST00000544510	TTC13	chr1	231075131	-	JAK2	chr9	5064882	+
5CDS-intron	ENST00000366662	ENST00000487310	TTC13	chr1	231075131	-	JAK2	chr9	5064882	+
In-frame	ENST00000414259	ENST00000539801	TTC13	chr1	231075131	-	JAK2	chr9	5064882	+
In-frame	ENST00000414259	ENST00000381652	TTC13	chr1	231075131	-	JAK2	chr9	5064882	+
In-frame	ENST00000414259	ENST00000544510	TTC13	chr1	231075131	-	JAK2	chr9	5064882	+
5CDS-intron	ENST00000414259	ENST00000487310	TTC13	chr1	231075131	-	JAK2	chr9	5064882	+
In-frame	ENST00000366661	ENST00000539801	TTC13	chr1	231079552	-	JAK2	chr9	5064883	+
In-frame	ENST00000366661	ENST00000381652	TTC13	chr1	231079552	-	JAK2	chr9	5064883	+
In-frame	ENST00000366661	ENST00000544510	TTC13	chr1	231079552	-	JAK2	chr9	5064883	+
5CDS-intron	ENST00000366661	ENST00000487310	TTC13	chr1	231079552	-	JAK2	chr9	5064883	+
intron-3CDS	ENST00000366662	ENST00000539801	TTC13	chr1	231079552	-	JAK2	chr9	5064883	+
intron-3CDS	ENST00000366662	ENST00000381652	TTC13	chr1	231079552	-	JAK2	chr9	5064883	+
intron-3CDS	ENST00000366662	ENST00000544510	TTC13	chr1	231079552	-	JAK2	chr9	5064883	+
intron-intron	ENST00000366662	ENST00000487310	TTC13	chr1	231079552	-	JAK2	chr9	5064883	+
intron-3CDS	ENST00000414259	ENST00000539801	TTC13	chr1	231079552	-	JAK2	chr9	5064883	+
intron-3CDS	ENST00000414259	ENST00000381652	TTC13	chr1	231079552	-	JAK2	chr9	5064883	+
intron-3CDS	ENST00000414259	ENST00000544510	TTC13	chr1	231079552	-	JAK2	chr9	5064883	+
intron-intron	ENST00000414259	ENST00000487310	TTC13	chr1	231079552	-	JAK2	chr9	5064883	+
In-frame	ENST00000366661	ENST00000539801	TTC13	chr1	231090079	-	JAK2	chr9	5064883	+
In-frame	ENST00000366661	ENST00000381652	TTC13	chr1	231090079	-	JAK2	chr9	5064883	+
In-frame	ENST00000366661	ENST00000544510	TTC13	chr1	231090079	-	JAK2	chr9	5064883	+
5CDS-intron	ENST00000366661	ENST00000487310	TTC13	chr1	231090079	-	JAK2	chr9	5064883	+
In-frame	ENST00000366662	ENST00000539801	TTC13	chr1	231090079	-	JAK2	chr9	5064883	+
In-frame	ENST00000366662	ENST00000381652	TTC13	chr1	231090079	-	JAK2	chr9	5064883	+
In-frame	ENST00000366662	ENST00000544510	TTC13	chr1	231090079	-	JAK2	chr9	5064883	+
5CDS-intron	ENST00000366662	ENST00000487310	TTC13	chr1	231090079	-	JAK2	chr9	5064883	+
In-frame	ENST00000414259	ENST00000539801	TTC13	chr1	231090079	-	JAK2	chr9	5064883	+
In-frame	ENST00000414259	ENST00000381652	TTC13	chr1	231090079	-	JAK2	chr9	5064883	+
In-frame	ENST00000414259	ENST00000544510	TTC13	chr1	231090079	-	JAK2	chr9	5064883	+
5CDS-intron	ENST00000414259	ENST00000487310	TTC13	chr1	231090079	-	JAK2	chr9	5064883	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000366661	TTC13	chr1	231075132	-	ENST00000539801	JAK2	chr9	5064883	+	3274	908	8	3250	1080
ENST00000366661	TTC13	chr1	231075132	-	ENST00000381652	JAK2	chr9	5064883	+	4643	908	8	3250	1080
ENST00000366661	TTC13	chr1	231075132	-	ENST00000544510	JAK2	chr9	5064883	+	3309	908	8	3250	1080
ENST00000366662	TTC13	chr1	231075132	-	ENST00000539801	JAK2	chr9	5064883	+	3136	770	29	3112	1027
ENST00000366662	TTC13	chr1	231075132	-	ENST00000381652	JAK2	chr9	5064883	+	4505	770	29	3112	1027
ENST00000366662	TTC13	chr1	231075132	-	ENST00000544510	JAK2	chr9	5064883	+	3171	770	29	3112	1027
ENST00000414259	TTC13	chr1	231075132	-	ENST00000539801	JAK2	chr9	5064883	+	3138	772	31	3114	1027
ENST00000414259	TTC13	chr1	231075132	-	ENST00000381652	JAK2	chr9	5064883	+	4507	772	31	3114	1027
ENST00000414259	TTC13	chr1	231075132	-	ENST00000544510	JAK2	chr9	5064883	+	3173	772	31	3114	1027
ENST00000366661	TTC13	chr1	231075131	-	ENST00000539801	JAK2	chr9	5064882	+	3274	908	8	3250	1080
ENST00000366661	TTC13	chr1	231075131	-	ENST00000381652	JAK2	chr9	5064882	+	4643	908	8	3250	1080
ENST00000366661	TTC13	chr1	231075131	-	ENST00000544510	JAK2	chr9	5064882	+	3309	908	8	3250	1080
ENST00000366662	TTC13	chr1	231075131	-	ENST00000539801	JAK2	chr9	5064882	+	3136	770	29	3112	1027
ENST00000366662	TTC13	chr1	231075131	-	ENST00000381652	JAK2	chr9	5064882	+	4505	770	29	3112	1027
ENST00000366662	TTC13	chr1	231075131	-	ENST00000544510	JAK2	chr9	5064882	+	3171	770	29	3112	1027
ENST00000414259	TTC13	chr1	231075131	-	ENST00000539801	JAK2	chr9	5064882	+	3138	772	31	3114	1027
ENST00000414259	TTC13	chr1	231075131	-	ENST00000381652	JAK2	chr9	5064882	+	4507	772	31	3114	1027
ENST00000414259	TTC13	chr1	231075131	-	ENST00000544510	JAK2	chr9	5064882	+	3173	772	31	3114	1027
ENST00000366661	TTC13	chr1	231079552	-	ENST00000539801	JAK2	chr9	5064883	+	3046	680	8	3022	1004
ENST00000366661	TTC13	chr1	231079552	-	ENST00000381652	JAK2	chr9	5064883	+	4415	680	8	3022	1004
ENST00000366661	TTC13	chr1	231079552	-	ENST00000544510	JAK2	chr9	5064883	+	3081	680	8	3022	1004
ENST00000366661	TTC13	chr1	231090079	-	ENST00000539801	JAK2	chr9	5064883	+	2887	521	8	2863	951
ENST00000366661	TTC13	chr1	231090079	-	ENST00000381652	JAK2	chr9	5064883	+	4256	521	8	2863	951
ENST00000366661	TTC13	chr1	231090079	-	ENST00000544510	JAK2	chr9	5064883	+	2922	521	8	2863	951
ENST00000366662	TTC13	chr1	231090079	-	ENST00000539801	JAK2	chr9	5064883	+	2908	542	29	2884	951
ENST00000366662	TTC13	chr1	231090079	-	ENST00000381652	JAK2	chr9	5064883	+	4277	542	29	2884	951
ENST00000366662	TTC13	chr1	231090079	-	ENST00000544510	JAK2	chr9	5064883	+	2943	542	29	2884	951
ENST00000414259	TTC13	chr1	231090079	-	ENST00000539801	JAK2	chr9	5064883	+	2910	544	31	2886	951
ENST00000414259	TTC13	chr1	231090079	-	ENST00000381652	JAK2	chr9	5064883	+	4279	544	31	2886	951
ENST00000414259	TTC13	chr1	231090079	-	ENST00000544510	JAK2	chr9	5064883	+	2945	544	31	2886	951

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000366661	ENST00000539801	TTC13	chr1	231075132	-	JAK2	chr9	5064883	+	0.000817559	0.9991824
ENST00000366661	ENST00000381652	TTC13	chr1	231075132	-	JAK2	chr9	5064883	+	0.000163512	0.99983644
ENST00000366661	ENST00000544510	TTC13	chr1	231075132	-	JAK2	chr9	5064883	+	0.000801881	0.99919814
ENST00000366662	ENST00000539801	TTC13	chr1	231075132	-	JAK2	chr9	5064883	+	0.000386289	0.9996137
ENST00000366662	ENST00000381652	TTC13	chr1	231075132	-	JAK2	chr9	5064883	+	6.75E-05	0.9999325
ENST00000366662	ENST00000544510	TTC13	chr1	231075132	-	JAK2	chr9	5064883	+	0.000377563	0.99962246
ENST00000414259	ENST00000539801	TTC13	chr1	231075132	-	JAK2	chr9	5064883	+	0.000384994	0.99961495
ENST00000414259	ENST00000381652	TTC13	chr1	231075132	-	JAK2	chr9	5064883	+	6.77E-05	0.9999323
ENST00000414259	ENST00000544510	TTC13	chr1	231075132	-	JAK2	chr9	5064883	+	0.000376356	0.99962366
ENST00000366661	ENST00000539801	TTC13	chr1	231075131	-	JAK2	chr9	5064882	+	0.000817559	0.9991824
ENST00000366661	ENST00000381652	TTC13	chr1	231075131	-	JAK2	chr9	5064882	+	0.000163512	0.99983644
ENST00000366661	ENST00000544510	TTC13	chr1	231075131	-	JAK2	chr9	5064882	+	0.000801881	0.99919814
ENST00000366662	ENST00000539801	TTC13	chr1	231075131	-	JAK2	chr9	5064882	+	0.000386289	0.9996137
ENST00000366662	ENST00000381652	TTC13	chr1	231075131	-	JAK2	chr9	5064882	+	6.75E-05	0.9999325
ENST00000366662	ENST00000544510	TTC13	chr1	231075131	-	JAK2	chr9	5064882	+	0.000377563	0.99962246
ENST00000414259	ENST00000539801	TTC13	chr1	231075131	-	JAK2	chr9	5064882	+	0.000384994	0.99961495
ENST00000414259	ENST00000381652	TTC13	chr1	231075131	-	JAK2	chr9	5064882	+	6.77E-05	0.9999323
ENST00000414259	ENST00000544510	TTC13	chr1	231075131	-	JAK2	chr9	5064882	+	0.000376356	0.99962366
ENST00000366661	ENST00000539801	TTC13	chr1	231079552	-	JAK2	chr9	5064883	+	0.000262902	0.9997371
ENST00000366661	ENST00000381652	TTC13	chr1	231079552	-	JAK2	chr9	5064883	+	6.06E-05	0.99993944
ENST00000366661	ENST00000544510	TTC13	chr1	231079552	-	JAK2	chr9	5064883	+	0.000257958	0.9997421
ENST00000366661	ENST00000539801	TTC13	chr1	231090079	-	JAK2	chr9	5064883	+	0.000389553	0.9996105
ENST00000366661	ENST00000381652	TTC13	chr1	231090079	-	JAK2	chr9	5064883	+	9.47E-05	0.9999052
ENST00000366661	ENST00000544510	TTC13	chr1	231090079	-	JAK2	chr9	5064883	+	0.000383062	0.99961686
ENST00000366662	ENST00000539801	TTC13	chr1	231090079	-	JAK2	chr9	5064883	+	0.000381649	0.9996183
ENST00000366662	ENST00000381652	TTC13	chr1	231090079	-	JAK2	chr9	5064883	+	9.45E-05	0.99990547
ENST00000366662	ENST00000544510	TTC13	chr1	231090079	-	JAK2	chr9	5064883	+	0.000376062	0.9996239
ENST00000414259	ENST00000539801	TTC13	chr1	231090079	-	JAK2	chr9	5064883	+	0.000379677	0.9996203
ENST00000414259	ENST00000381652	TTC13	chr1	231090079	-	JAK2	chr9	5064883	+	9.45E-05	0.99990547
ENST00000414259	ENST00000544510	TTC13	chr1	231090079	-	JAK2	chr9	5064883	+	0.000374345	0.9996257

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Fusion Genomic Features for TTC13-JAK2

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
TTC13	chr1	231075131	-	JAK2	chr9	5064882	+	0.001407714	0.9985923
TTC13	chr1	231075131	-	JAK2	chr9	5064882	+	0.001407714	0.9985923
TTC13	chr1	231090078	-	JAK2	chr9	5064882	+	2.05E-06	0.999998
TTC13	chr1	231079551	-	JAK2	chr9	5064882	+	4.54E-07	0.9999995
TTC13	chr1	231075131	-	JAK2	chr9	5064882	+	0.001407714	0.9985923
TTC13	chr1	231075131	-	JAK2	chr9	5064882	+	0.001407714	0.9985923
TTC13	chr1	231090078	-	JAK2	chr9	5064882	+	2.05E-06	0.999998
TTC13	chr1	231079551	-	JAK2	chr9	5064882	+	4.54E-07	0.9999995

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TTC13-JAK2

Go to
FGviewer for the breakpoints of chr1:231075132-chr9:5064883
.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	JAK2 O60674
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.	FUNCTION: Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors such as growth hormone (GHR), prolactin (PRLR), leptin (LEPR), erythropoietin (EPOR), thrombopoietin (THPO); or type II receptors including IFN-alpha, IFN-beta, IFN-gamma and multiple interleukins (PubMed:7615558). Following ligand-binding to cell surface receptors, phosphorylates specific tyrosine residues on the cytoplasmic tails of the receptor, creating docking sites for STATs proteins (PubMed:9618263). Subsequently, phosphorylates the STATs proteins once they are recruited to the receptor. Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, cell stimulation with erythropoietin (EPO) during erythropoiesis leads to JAK2 autophosphorylation, activation, and its association with erythropoietin receptor (EPOR) that becomes phosphorylated in its cytoplasmic domain. Then, STAT5 (STAT5A or STAT5B) is recruited, phosphorylated and activated by JAK2. Once activated, dimerized STAT5 translocates into the nucleus and promotes the transcription of several essential genes involved in the modulation of erythropoiesis. Part of a signaling cascade that is activated by increased cellular retinol and that leads to the activation of STAT5 (STAT5A or STAT5B) (PubMed:21368206). In addition, JAK2 mediates angiotensin-2-induced ARHGEF1 phosphorylation (PubMed:20098430). Plays a role in cell cycle by phosphorylating CDKN1B (PubMed:21423214). Cooperates with TEC through reciprocal phosphorylation to mediate cytokine-driven activation of FOS transcription. In the nucleus, plays a key role in chromatin by specifically mediating phosphorylation of 'Tyr-41' of histone H3 (H3Y41ph), a specific tag that promotes exclusion of CBX5 (HP1 alpha) from chromatin (PubMed:19783980). {ECO:0000269\|PubMed:12023369, ECO:0000269\|PubMed:19783980, ECO:0000269\|PubMed:20098430, ECO:0000269\|PubMed:21368206, ECO:0000269\|PubMed:21423214, ECO:0000269\|PubMed:7615558, ECO:0000269\|PubMed:9618263}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

TTC13

chr1:231075131

chr9:5064882

ENST00000366661

143_176

300.0

861.0

Repeat

Note=TPR 1

Hgene

TTC13

chr1:231075131

chr9:5064882

ENST00000366661

216_248

300.0

861.0

Repeat

Note=TPR 2

Hgene

TTC13

chr1:231075131

chr9:5064882

ENST00000366661

249_282

300.0

861.0

Repeat

Note=TPR 3

Hgene

TTC13

chr1:231075131

chr9:5064882

ENST00000366662

143_176

247.0

807.0

Repeat

Note=TPR 1

Hgene

TTC13

chr1:231075131

chr9:5064882

ENST00000366662

216_248

247.0

807.0

Repeat

Note=TPR 2

Hgene

TTC13

chr1:231075132

chr9:5064883

ENST00000366661

143_176

300.0

861.0

Repeat

Note=TPR 1

Hgene

TTC13

chr1:231075132

chr9:5064883

ENST00000366661

216_248

300.0

861.0

Repeat

Note=TPR 2

Hgene

TTC13

chr1:231075132

chr9:5064883

ENST00000366661

249_282

300.0

861.0

Repeat

Note=TPR 3

Hgene

TTC13

chr1:231075132

chr9:5064883

ENST00000366662

143_176

247.0

807.0

Repeat

Note=TPR 1

Hgene

TTC13

chr1:231075132

chr9:5064883

ENST00000366662

216_248

247.0

807.0

Repeat

Note=TPR 2

Hgene

TTC13

chr1:231079552

chr9:5064883

ENST00000366661

143_176

224.0

861.0

Repeat

Note=TPR 1

Tgene

JAK2

chr1:231075131

chr9:5064882

ENST00000381652

401_482

352.0

1133.0

Domain

SH2%3B atypical

Tgene

JAK2

chr1:231075131

chr9:5064882

ENST00000381652

545_809

352.0

1133.0

Domain

Protein kinase 1

Tgene

JAK2

chr1:231075131

chr9:5064882

ENST00000381652

849_1124

352.0

1133.0

Domain

Protein kinase 2

Tgene

JAK2

chr1:231075131

chr9:5064882

ENST00000539801

401_482

352.0

1133.0

Domain

SH2%3B atypical

Tgene

JAK2

chr1:231075131

chr9:5064882

ENST00000539801

545_809

352.0

1133.0

Domain

Protein kinase 1

Tgene

JAK2

chr1:231075131

chr9:5064882

ENST00000539801

849_1124

352.0

1133.0

Domain

Protein kinase 2

Tgene

JAK2

chr1:231075132

chr9:5064883

ENST00000381652

401_482

352.0

1133.0

Domain

SH2%3B atypical

Tgene

JAK2

chr1:231075132

chr9:5064883

ENST00000381652

545_809

352.0

1133.0

Domain

Protein kinase 1

Tgene

JAK2

chr1:231075132

chr9:5064883

ENST00000381652

849_1124

352.0

1133.0

Domain

Protein kinase 2

Tgene

JAK2

chr1:231075132

chr9:5064883

ENST00000539801

401_482

352.0

1133.0

Domain

SH2%3B atypical

Tgene

JAK2

chr1:231075132

chr9:5064883

ENST00000539801

545_809

352.0

1133.0

Domain

Protein kinase 1

Tgene

JAK2

chr1:231075132

chr9:5064883

ENST00000539801

849_1124

352.0

1133.0

Domain

Protein kinase 2

Tgene

JAK2

chr1:231079552

chr9:5064883

ENST00000381652

401_482

352.0

1133.0

Domain

SH2%3B atypical

Tgene

JAK2

chr1:231079552

chr9:5064883

ENST00000381652

545_809

352.0

1133.0

Domain

Protein kinase 1

Tgene

JAK2

chr1:231079552

chr9:5064883

ENST00000381652

849_1124

352.0

1133.0

Domain

Protein kinase 2

Tgene

JAK2

chr1:231079552

chr9:5064883

ENST00000539801

401_482

352.0

1133.0

Domain

SH2%3B atypical

Tgene

JAK2

chr1:231079552

chr9:5064883

ENST00000539801

545_809

352.0

1133.0

Domain

Protein kinase 1

Tgene

JAK2

chr1:231079552

chr9:5064883

ENST00000539801

849_1124

352.0

1133.0

Domain

Protein kinase 2

Tgene

JAK2

chr1:231090079

chr9:5064883

ENST00000381652

401_482

352.0

1133.0

Domain

SH2%3B atypical

Tgene

JAK2

chr1:231090079

chr9:5064883

ENST00000381652

545_809

352.0

1133.0

Domain

Protein kinase 1

Tgene

JAK2

chr1:231090079

chr9:5064883

ENST00000381652

849_1124

352.0

1133.0

Domain

Protein kinase 2

Tgene

JAK2

chr1:231090079

chr9:5064883

ENST00000539801

401_482

352.0

1133.0

Domain

SH2%3B atypical

Tgene

JAK2

chr1:231090079

chr9:5064883

ENST00000539801

545_809

352.0

1133.0

Domain

Protein kinase 1

Tgene

JAK2

chr1:231090079

chr9:5064883

ENST00000539801

849_1124

352.0

1133.0

Domain

Protein kinase 2

Tgene

JAK2

chr1:231075131

chr9:5064882

ENST00000381652

855_863

352.0

1133.0

Nucleotide binding

ATP

Tgene

JAK2

chr1:231075131

chr9:5064882

ENST00000539801

855_863

352.0

1133.0

Nucleotide binding

ATP

Tgene

JAK2

chr1:231075132

chr9:5064883

ENST00000381652

855_863

352.0

1133.0

Nucleotide binding

ATP

Tgene

JAK2

chr1:231075132

chr9:5064883

ENST00000539801

855_863

352.0

1133.0

Nucleotide binding

ATP

Tgene

JAK2

chr1:231079552

chr9:5064883

ENST00000381652

855_863

352.0

1133.0

Nucleotide binding

ATP

Tgene

JAK2

chr1:231079552

chr9:5064883

ENST00000539801

855_863

352.0

1133.0

Nucleotide binding

ATP

Tgene

JAK2

chr1:231090079

chr9:5064883

ENST00000381652

855_863

352.0

1133.0

Nucleotide binding

ATP

Tgene

JAK2

chr1:231090079

chr9:5064883

ENST00000539801

855_863

352.0

1133.0

Nucleotide binding

ATP

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

TTC13

chr1:231075131

chr9:5064882

ENST00000366661

284_316

300.0

861.0

Repeat

Note=TPR 4

Hgene

TTC13

chr1:231075131

chr9:5064882

ENST00000366661

317_350

300.0

861.0

Repeat

Note=TPR 5

Hgene

TTC13

chr1:231075131

chr9:5064882

ENST00000366661

352_384

300.0

861.0

Repeat

Note=TPR 6

Hgene

TTC13

chr1:231075131

chr9:5064882

ENST00000366661

386_418

300.0

861.0

Repeat

Note=TPR 7

Hgene

TTC13

chr1:231075131

chr9:5064882

ENST00000366662

249_282

247.0

807.0

Repeat

Note=TPR 3

Hgene

TTC13

chr1:231075131

chr9:5064882

ENST00000366662

284_316

247.0

807.0

Repeat

Note=TPR 4

Hgene

TTC13

chr1:231075131

chr9:5064882

ENST00000366662

317_350

247.0

807.0

Repeat

Note=TPR 5

Hgene

TTC13

chr1:231075131

chr9:5064882

ENST00000366662

352_384

247.0

807.0

Repeat

Note=TPR 6

Hgene

TTC13

chr1:231075131

chr9:5064882

ENST00000366662

386_418

247.0

807.0

Repeat

Note=TPR 7

Hgene

TTC13

chr1:231075132

chr9:5064883

ENST00000366661

284_316

300.0

861.0

Repeat

Note=TPR 4

Hgene

TTC13

chr1:231075132

chr9:5064883

ENST00000366661

317_350

300.0

861.0

Repeat

Note=TPR 5

Hgene

TTC13

chr1:231075132

chr9:5064883

ENST00000366661

352_384

300.0

861.0

Repeat

Note=TPR 6

Hgene

TTC13

chr1:231075132

chr9:5064883

ENST00000366661

386_418

300.0

861.0

Repeat

Note=TPR 7

Hgene

TTC13

chr1:231075132

chr9:5064883

ENST00000366662

249_282

247.0

807.0

Repeat

Note=TPR 3

Hgene

TTC13

chr1:231075132

chr9:5064883

ENST00000366662

284_316

247.0

807.0

Repeat

Note=TPR 4

Hgene

TTC13

chr1:231075132

chr9:5064883

ENST00000366662

317_350

247.0

807.0

Repeat

Note=TPR 5

Hgene

TTC13

chr1:231075132

chr9:5064883

ENST00000366662

352_384

247.0

807.0

Repeat

Note=TPR 6

Hgene

TTC13

chr1:231075132

chr9:5064883

ENST00000366662

386_418

247.0

807.0

Repeat

Note=TPR 7

Hgene

TTC13

chr1:231079552

chr9:5064883

ENST00000366661

216_248

224.0

861.0

Repeat

Note=TPR 2

Hgene

TTC13

chr1:231079552

chr9:5064883

ENST00000366661

249_282

224.0

861.0

Repeat

Note=TPR 3

Hgene

TTC13

chr1:231079552

chr9:5064883

ENST00000366661

284_316

224.0

861.0

Repeat

Note=TPR 4

Hgene

TTC13

chr1:231079552

chr9:5064883

ENST00000366661

317_350

224.0

861.0

Repeat

Note=TPR 5

Hgene

TTC13

chr1:231079552

chr9:5064883

ENST00000366661

352_384

224.0

861.0

Repeat

Note=TPR 6

Hgene

TTC13

chr1:231079552

chr9:5064883

ENST00000366661

386_418

224.0

861.0

Repeat

Note=TPR 7

Hgene

TTC13

chr1:231079552

chr9:5064883

ENST00000366662

143_176

807.0

Repeat

Note=TPR 1

Hgene

TTC13

chr1:231079552

chr9:5064883

ENST00000366662

216_248

807.0

Repeat

Note=TPR 2

Hgene

TTC13

chr1:231079552

chr9:5064883

ENST00000366662

249_282

807.0

Repeat

Note=TPR 3

Hgene

TTC13

chr1:231079552

chr9:5064883

ENST00000366662

284_316

807.0

Repeat

Note=TPR 4

Hgene

TTC13

chr1:231079552

chr9:5064883

ENST00000366662

317_350

807.0

Repeat

Note=TPR 5

Hgene

TTC13

chr1:231079552

chr9:5064883

ENST00000366662

352_384

807.0

Repeat

Note=TPR 6

Hgene

TTC13

chr1:231079552

chr9:5064883

ENST00000366662

386_418

807.0

Repeat

Note=TPR 7

Hgene

TTC13

chr1:231090079

chr9:5064883

ENST00000366661

143_176

171.0

861.0

Repeat

Note=TPR 1

Hgene

TTC13

chr1:231090079

chr9:5064883

ENST00000366661

216_248

171.0

861.0

Repeat

Note=TPR 2

Hgene

TTC13

chr1:231090079

chr9:5064883

ENST00000366661

249_282

171.0

861.0

Repeat

Note=TPR 3

Hgene

TTC13

chr1:231090079

chr9:5064883

ENST00000366661

284_316

171.0

861.0

Repeat

Note=TPR 4

Hgene

TTC13

chr1:231090079

chr9:5064883

ENST00000366661

317_350

171.0

861.0

Repeat

Note=TPR 5

Hgene

TTC13

chr1:231090079

chr9:5064883

ENST00000366661

352_384

171.0

861.0

Repeat

Note=TPR 6

Hgene

TTC13

chr1:231090079

chr9:5064883

ENST00000366661

386_418

171.0

861.0

Repeat

Note=TPR 7

Hgene

TTC13

chr1:231090079

chr9:5064883

ENST00000366662

143_176

171.0

807.0

Repeat

Note=TPR 1

Hgene

TTC13

chr1:231090079

chr9:5064883

ENST00000366662

216_248

171.0

807.0

Repeat

Note=TPR 2

Hgene

TTC13

chr1:231090079

chr9:5064883

ENST00000366662

249_282

171.0

807.0

Repeat

Note=TPR 3

Hgene

TTC13

chr1:231090079

chr9:5064883

ENST00000366662

284_316

171.0

807.0

Repeat

Note=TPR 4

Hgene

TTC13

chr1:231090079

chr9:5064883

ENST00000366662

317_350

171.0

807.0

Repeat

Note=TPR 5

Hgene

TTC13

chr1:231090079

chr9:5064883

ENST00000366662

352_384

171.0

807.0

Repeat

Note=TPR 6

Hgene

TTC13

chr1:231090079

chr9:5064883

ENST00000366662

386_418

171.0

807.0

Repeat

Note=TPR 7

Tgene

JAK2

chr1:231075131

chr9:5064882

ENST00000381652

37_380

352.0

1133.0

Domain

FERM

Tgene

JAK2

chr1:231075131

chr9:5064882

ENST00000539801

37_380

352.0

1133.0

Domain

FERM

Tgene

JAK2

chr1:231075132

chr9:5064883

ENST00000381652

37_380

352.0

1133.0

Domain

FERM

Tgene

JAK2

chr1:231075132

chr9:5064883

ENST00000539801

37_380

352.0

1133.0

Domain

FERM

Tgene

JAK2

chr1:231079552

chr9:5064883

ENST00000381652

37_380

352.0

1133.0

Domain

FERM

Tgene

JAK2

chr1:231079552

chr9:5064883

ENST00000539801

37_380

352.0

1133.0

Domain

FERM

Tgene

JAK2

chr1:231090079

chr9:5064883

ENST00000381652

37_380

352.0

1133.0

Domain

FERM

Tgene

JAK2

chr1:231090079

chr9:5064883

ENST00000539801

37_380

352.0

1133.0

Domain

FERM

Top

Fusion Gene Sequence for TTC13-JAK2

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>In-frame_ENST00000366661_ENST00000539801_TCGA-E9-A22D-01A_TTC13_chr1_231075132_-_JAK2_chr9_5064883_length(transcript)=3274nt_BP=908nt
GAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGGGCGCCGCCCGGCGTGTCCTGC
TGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGCCGCTCTCCCTGCTCAAGCAGG
AGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACTGGGGGGACCAGTACTCTGCCG
AGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTGACTCCTTGCTTTCCCTCAACA
CTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATGACAGCACAAATGAAGAGTTAG
CTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTCAGGAGGAGCCTGATCTGGTTA
GTGCAATTTATGGCCGAGGGATAGCCTATGGAAAGAAGGGACTACATGACATTAAGAATGCTGAGCTTGCTCTGTTCGAACTGAGCCGAG
TAATTACCTTGGAACCAGATCGTCCAGAGGTATTTGAGCAGCGAGCAGAAATTCTGTCCCCTCTGGGACGAATTAATGAAGCAGTGAATG
ACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAGACATCGGGGAACCCTGTACTTCATATCAGAGGACTATGCAACAG
CCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCCTATAGCTATGCTATACAAAGGTTTAACTTTCTTTCACAGAGGAC
TTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCGTGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCAC
ATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATATACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCA
TTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTCGATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTG
CTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAAAAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGA
ACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTGTTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTC
CCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATGGTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTA
CTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGATATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTT
TTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAACAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACT
ATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTCACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAG
ACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATACATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGA
AACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAGAAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTC
TGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCAAACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGG
ACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAAATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTG
GTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTGCTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGC
ATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATAATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAG
CCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTATTAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCC
TGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAGAGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATT
TTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTGGGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAG
AGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTACAGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTG
CTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAAGTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATC
ACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGTATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGA
GAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTGGGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAG
TAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCACTGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCT
TTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAAGTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAAC
AAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATGGAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATA
TGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCTTTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACA

>In-frame_ENST00000366661_ENST00000539801_TCGA-E9-A22D-01A_TTC13_chr1_231075132_-_JAK2_chr9_5064883_length(amino acids)=1080AA_start in transcript=8_stop in transcript=3250
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG
ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEEPDLVSAI
YGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHE
DFQQSLELNKNQPIAMLYKGLTFFHRGLLKEIELSSLREALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISK
LKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLSGTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPK
PKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSE
SFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLI
REEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQL
PAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGS
VEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIK
LLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGV
VLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG

--------------------------------------------------------------
>In-frame_ENST00000366661_ENST00000381652_TCGA-E9-A22D-01A_TTC13_chr1_231075132_-_JAK2_chr9_5064883_length(transcript)=4643nt_BP=908nt
GAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGGGCGCCGCCCGGCGTGTCCTGC
TGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGCCGCTCTCCCTGCTCAAGCAGG
AGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACTGGGGGGACCAGTACTCTGCCG
AGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTGACTCCTTGCTTTCCCTCAACA
CTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATGACAGCACAAATGAAGAGTTAG
CTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTCAGGAGGAGCCTGATCTGGTTA
GTGCAATTTATGGCCGAGGGATAGCCTATGGAAAGAAGGGACTACATGACATTAAGAATGCTGAGCTTGCTCTGTTCGAACTGAGCCGAG
TAATTACCTTGGAACCAGATCGTCCAGAGGTATTTGAGCAGCGAGCAGAAATTCTGTCCCCTCTGGGACGAATTAATGAAGCAGTGAATG
ACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAGACATCGGGGAACCCTGTACTTCATATCAGAGGACTATGCAACAG
CCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCCTATAGCTATGCTATACAAAGGTTTAACTTTCTTTCACAGAGGAC
TTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCGTGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCAC
ATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATATACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCA
TTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTCGATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTG
CTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAAAAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGA
ACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTGTTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTC
CCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATGGTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTA
CTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGATATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTT
TTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAACAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACT
ATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTCACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAG
ACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATACATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGA
AACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAGAAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTC
TGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCAAACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGG
ACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAAATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTG
GTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTGCTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGC
ATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATAATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAG
CCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTATTAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCC
TGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAGAGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATT
TTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTGGGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAG
AGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTACAGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTG
CTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAAGTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATC
ACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGTATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGA
GAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTGGGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAG
TAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCACTGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCT
TTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAAGTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAAC
AAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATGGAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATA
TGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCTTTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACA
TGGCTGGATGAAAGAAATGACCTTCATTCTGAGACCAAAGTAGATTTACAGAACAAAGTTTTATATTTCACATTGCTGTGGACTATTATT
ACATATATCATTATTATATAAATCATGATGCTAGCCAGCAAAGATGTGAAAATATCTGCTCAAAACTTTCAAAGTTTAGTAAGTTTTTCT
TCATGAGGCCACCAGTAAAAGACATTAATGAGAATTCCTTAGCAAGGATTTTGTAAGAAGTTTCTTAAACATTGTCAGTTAACATCACTC
TTGTCTGGCAAAAGAAAAAAAATAGACTTTTTCAACTCAGCTTTTTGAGACCTGAAAAAATTATTATGTAAATTTTGCAATGTTAAAGAT
GCACAGAATATGTATGTATAGTTTTTACCACAGTGGATGTATAATACCTTGGCATCTTGTGTGATGTTTTACACACATGAGGGCTGGTGT
TCATTAATACTGTTTTCTAATTTTTCCATAGTTAATCTATAATTAATTACTTCACTATACAAACAAATTAAGATGTTCAGATAATTGAAT
AAGTACCTTTGTGTCCTTGTTCATTTATATCGCTGGCCAGCATTATAAGCAGGTGTATACTTTTAGCTTGTAGTTCCATGTACTGTAAAT
ATTTTTCACATAAAGGGAACAAATGTCTAGTTTTATTTGTATAGGAAATTTCCCTGACCCTAAATAATACATTTTGAAATGAAACAAGCT
TACAAAGATATAATCTATTTTATTATGGTTTCCCTTGTATCTATTTGTGGTGAATGTGTTTTTTAAATGGAACTATCTCCAAATTTTTCT
AAGACTACTATGAACAGTTTTCTTTTAAAATTTTGAGATTAAGAATGCCAGGAATATTGTCATCCTTTGAGCTGCTGACTGCCAATAACA
TTCTTCGATCTCTGGGATTTATGCTCATGAACTAAATTTAAGCTTAAGCCATAAAATAGATTAGATTGTTTTTTAAAAATGGATAGCTCA
TTAAGAAGTGCAGCAGGTTAAGAATTTTTTCCTAAAGACTGTATATTTGAGGGGTTTCAGAATTTTGCATTGCAGTCATAGAAGAGATTT
ATTTCCTTTTTAGAGGGGAAATGAGGTAAATAAGTAAAAAAGTATGCTTGTTAATTTTATTCAAGAATGCCAGTAGAAAATTCATAACGT
GTATCTTTAAGAAAAATGAGCATACATCTTAAATCTTTTCAATTAAGTATAAGGGGTTGTTCGTTGTTGTCATTTGTTATAGTGCTACTC
CACTTTAGACACCATAGCTAAAATAAAATATGGTGGGTTTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTATTTATAC

>In-frame_ENST00000366661_ENST00000381652_TCGA-E9-A22D-01A_TTC13_chr1_231075132_-_JAK2_chr9_5064883_length(amino acids)=1080AA_start in transcript=8_stop in transcript=3250
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG
ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEEPDLVSAI
YGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHE
DFQQSLELNKNQPIAMLYKGLTFFHRGLLKEIELSSLREALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISK
LKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLSGTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPK
PKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSE
SFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLI
REEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQL
PAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGS
VEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIK
LLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGV
VLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG

--------------------------------------------------------------
>In-frame_ENST00000366661_ENST00000544510_TCGA-E9-A22D-01A_TTC13_chr1_231075132_-_JAK2_chr9_5064883_length(transcript)=3309nt_BP=908nt
GAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGGGCGCCGCCCGGCGTGTCCTGC
TGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGCCGCTCTCCCTGCTCAAGCAGG
AGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACTGGGGGGACCAGTACTCTGCCG
AGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTGACTCCTTGCTTTCCCTCAACA
CTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATGACAGCACAAATGAAGAGTTAG
CTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTCAGGAGGAGCCTGATCTGGTTA
GTGCAATTTATGGCCGAGGGATAGCCTATGGAAAGAAGGGACTACATGACATTAAGAATGCTGAGCTTGCTCTGTTCGAACTGAGCCGAG
TAATTACCTTGGAACCAGATCGTCCAGAGGTATTTGAGCAGCGAGCAGAAATTCTGTCCCCTCTGGGACGAATTAATGAAGCAGTGAATG
ACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAGACATCGGGGAACCCTGTACTTCATATCAGAGGACTATGCAACAG
CCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCCTATAGCTATGCTATACAAAGGTTTAACTTTCTTTCACAGAGGAC
TTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCGTGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCAC
ATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATATACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCA
TTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTCGATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTG
CTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAAAAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGA
ACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTGTTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTC
CCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATGGTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTA
CTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGATATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTT
TTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAACAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACT
ATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTCACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAG
ACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATACATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGA
AACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAGAAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTC
TGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCAAACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGG
ACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAAATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTG
GTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTGCTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGC
ATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATAATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAG
CCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTATTAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCC
TGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAGAGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATT
TTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTGGGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAG
AGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTACAGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTG
CTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAAGTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATC
ACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGTATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGA
GAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTGGGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAG
TAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCACTGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCT
TTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAAGTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAAC
AAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATGGAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATA
TGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCTTTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACA

>In-frame_ENST00000366661_ENST00000544510_TCGA-E9-A22D-01A_TTC13_chr1_231075132_-_JAK2_chr9_5064883_length(amino acids)=1080AA_start in transcript=8_stop in transcript=3250
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG
ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEEPDLVSAI
YGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHE
DFQQSLELNKNQPIAMLYKGLTFFHRGLLKEIELSSLREALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISK
LKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLSGTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPK
PKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSE
SFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLI
REEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQL
PAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGS
VEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIK
LLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGV
VLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG

--------------------------------------------------------------
>In-frame_ENST00000366662_ENST00000539801_TCGA-E9-A22D-01A_TTC13_chr1_231075132_-_JAK2_chr9_5064883_length(transcript)=3136nt_BP=770nt
GGGCTGTCGCGCATGCGCCTTGAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGG
GCGCCGCCCGGCGTGTCCTGCTGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGC
CGCTCTCCCTGCTCAAGCAGGAGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACT
GGGGGGACCAGTACTCTGCCGAGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTG
ACTCCTTGCTTTCCCTCAACACTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATG
ACAGCACAAATGAAGAGTTAGCTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTC
AGATTCTGTCCCCTCTGGGACGAATTAATGAAGCAGTGAATGACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAGAC
ATCGGGGAACCCTGTACTTCATATCAGAGGACTATGCAACAGCCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCCTA
TAGCTATGCTATACAAAGGTTTAACTTTCTTTCACAGAGGACTTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCG
TGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATA
TACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTC
GATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAA
AAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTG
TTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATG
GTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGA
TATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAA
CAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTC
ACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATA
CATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAG
AAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCA
AACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAA
ATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTG
CTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATA
ATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTAT
TAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAG
AGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTG
GGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTAC
AGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAA
GTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGT
ATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTG
GGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCAC
TGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAA
GTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATG
GAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCT

>In-frame_ENST00000366662_ENST00000539801_TCGA-E9-A22D-01A_TTC13_chr1_231075132_-_JAK2_chr9_5064883_length(amino acids)=1027AA_start in transcript=29_stop in transcript=3112
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG
ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQILSPLGRIN
EAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEIELSSLREALSFVSLIDGYYRL
TADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLS
GTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGT
FTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCI
NILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATD
KWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNM
RIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKG
VCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDK
EYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCP

--------------------------------------------------------------
>In-frame_ENST00000366662_ENST00000381652_TCGA-E9-A22D-01A_TTC13_chr1_231075132_-_JAK2_chr9_5064883_length(transcript)=4505nt_BP=770nt
GGGCTGTCGCGCATGCGCCTTGAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGG
GCGCCGCCCGGCGTGTCCTGCTGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGC
CGCTCTCCCTGCTCAAGCAGGAGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACT
GGGGGGACCAGTACTCTGCCGAGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTG
ACTCCTTGCTTTCCCTCAACACTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATG
ACAGCACAAATGAAGAGTTAGCTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTC
AGATTCTGTCCCCTCTGGGACGAATTAATGAAGCAGTGAATGACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAGAC
ATCGGGGAACCCTGTACTTCATATCAGAGGACTATGCAACAGCCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCCTA
TAGCTATGCTATACAAAGGTTTAACTTTCTTTCACAGAGGACTTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCG
TGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATA
TACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTC
GATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAA
AAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTG
TTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATG
GTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGA
TATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAA
CAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTC
ACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATA
CATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAG
AAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCA
AACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAA
ATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTG
CTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATA
ATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTAT
TAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAG
AGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTG
GGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTAC
AGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAA
GTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGT
ATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTG
GGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCAC
TGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAA
GTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATG
GAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCT
TTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACATGGCTGGATGAAAGAAATGACCTTCATTCTGAGACCAAAGTAGATTTA
CAGAACAAAGTTTTATATTTCACATTGCTGTGGACTATTATTACATATATCATTATTATATAAATCATGATGCTAGCCAGCAAAGATGTG
AAAATATCTGCTCAAAACTTTCAAAGTTTAGTAAGTTTTTCTTCATGAGGCCACCAGTAAAAGACATTAATGAGAATTCCTTAGCAAGGA
TTTTGTAAGAAGTTTCTTAAACATTGTCAGTTAACATCACTCTTGTCTGGCAAAAGAAAAAAAATAGACTTTTTCAACTCAGCTTTTTGA
GACCTGAAAAAATTATTATGTAAATTTTGCAATGTTAAAGATGCACAGAATATGTATGTATAGTTTTTACCACAGTGGATGTATAATACC
TTGGCATCTTGTGTGATGTTTTACACACATGAGGGCTGGTGTTCATTAATACTGTTTTCTAATTTTTCCATAGTTAATCTATAATTAATT
ACTTCACTATACAAACAAATTAAGATGTTCAGATAATTGAATAAGTACCTTTGTGTCCTTGTTCATTTATATCGCTGGCCAGCATTATAA
GCAGGTGTATACTTTTAGCTTGTAGTTCCATGTACTGTAAATATTTTTCACATAAAGGGAACAAATGTCTAGTTTTATTTGTATAGGAAA
TTTCCCTGACCCTAAATAATACATTTTGAAATGAAACAAGCTTACAAAGATATAATCTATTTTATTATGGTTTCCCTTGTATCTATTTGT
GGTGAATGTGTTTTTTAAATGGAACTATCTCCAAATTTTTCTAAGACTACTATGAACAGTTTTCTTTTAAAATTTTGAGATTAAGAATGC
CAGGAATATTGTCATCCTTTGAGCTGCTGACTGCCAATAACATTCTTCGATCTCTGGGATTTATGCTCATGAACTAAATTTAAGCTTAAG
CCATAAAATAGATTAGATTGTTTTTTAAAAATGGATAGCTCATTAAGAAGTGCAGCAGGTTAAGAATTTTTTCCTAAAGACTGTATATTT
GAGGGGTTTCAGAATTTTGCATTGCAGTCATAGAAGAGATTTATTTCCTTTTTAGAGGGGAAATGAGGTAAATAAGTAAAAAAGTATGCT
TGTTAATTTTATTCAAGAATGCCAGTAGAAAATTCATAACGTGTATCTTTAAGAAAAATGAGCATACATCTTAAATCTTTTCAATTAAGT
ATAAGGGGTTGTTCGTTGTTGTCATTTGTTATAGTGCTACTCCACTTTAGACACCATAGCTAAAATAAAATATGGTGGGTTTTGTGTGTG
TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTATTTATACAAAACTTAAAATACTTGCTGTTTTGATTAAAAAGAAAATAGTTTCTTA

>In-frame_ENST00000366662_ENST00000381652_TCGA-E9-A22D-01A_TTC13_chr1_231075132_-_JAK2_chr9_5064883_length(amino acids)=1027AA_start in transcript=29_stop in transcript=3112
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG
ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQILSPLGRIN
EAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEIELSSLREALSFVSLIDGYYRL
TADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLS
GTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGT
FTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCI
NILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATD
KWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNM
RIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKG
VCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDK
EYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCP

--------------------------------------------------------------
>In-frame_ENST00000366662_ENST00000544510_TCGA-E9-A22D-01A_TTC13_chr1_231075132_-_JAK2_chr9_5064883_length(transcript)=3171nt_BP=770nt
GGGCTGTCGCGCATGCGCCTTGAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGG
GCGCCGCCCGGCGTGTCCTGCTGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGC
CGCTCTCCCTGCTCAAGCAGGAGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACT
GGGGGGACCAGTACTCTGCCGAGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTG
ACTCCTTGCTTTCCCTCAACACTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATG
ACAGCACAAATGAAGAGTTAGCTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTC
AGATTCTGTCCCCTCTGGGACGAATTAATGAAGCAGTGAATGACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAGAC
ATCGGGGAACCCTGTACTTCATATCAGAGGACTATGCAACAGCCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCCTA
TAGCTATGCTATACAAAGGTTTAACTTTCTTTCACAGAGGACTTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCG
TGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATA
TACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTC
GATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAA
AAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTG
TTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATG
GTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGA
TATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAA
CAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTC
ACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATA
CATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAG
AAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCA
AACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAA
ATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTG
CTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATA
ATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTAT
TAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAG
AGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTG
GGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTAC
AGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAA
GTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGT
ATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTG
GGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCAC
TGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAA
GTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATG
GAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCT
TTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACATGGCTGGATGAAAGAAATGACCTTCATTCTGAGACCAAAGTAGATTTA

>In-frame_ENST00000366662_ENST00000544510_TCGA-E9-A22D-01A_TTC13_chr1_231075132_-_JAK2_chr9_5064883_length(amino acids)=1027AA_start in transcript=29_stop in transcript=3112
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG
ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQILSPLGRIN
EAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEIELSSLREALSFVSLIDGYYRL
TADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLS
GTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGT
FTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCI
NILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATD
KWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNM
RIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKG
VCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDK
EYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCP

--------------------------------------------------------------
>In-frame_ENST00000414259_ENST00000539801_TCGA-E9-A22D-01A_TTC13_chr1_231075132_-_JAK2_chr9_5064883_length(transcript)=3138nt_BP=772nt
AAGGGCTGTCGCGCATGCGCCTTGAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGC
GGGCGCCGCCCGGCGTGTCCTGCTGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTC
GCCGCTCTCCCTGCTCAAGCAGGAGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGA
CTGGGGGGACCAGTACTCTGCCGAGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTG
TGACTCCTTGCTTTCCCTCAACACTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAA
TGACAGCACAAATGAAGAGTTAGCTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCT
TCAGATTCTGTCCCCTCTGGGACGAATTAATGAAGCAGTGAATGACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAG
ACATCGGGGAACCCTGTACTTCATATCAGAGGACTATGCAACAGCCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCC
TATAGCTATGCTATACAAAGGTTTAACTTTCTTTCACAGAGGACTTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTT
CGTGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAA
TATACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACT
TCGATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTAC
AAAAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAAC
TGTTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAA
TGGTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTT
GATATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGA
AACAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTC
TCACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGA
TACATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGA
AGAAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCAT
CAAACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGA
AAATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAG
TGCTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAA
TAATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACT
ATTAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGA
AGAGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACAC
TGGGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCT
ACAGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGG
AAGTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGA
GTATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTT
TGGGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATC
ACTGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAA
AAGTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAA
TGGAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTC

>In-frame_ENST00000414259_ENST00000539801_TCGA-E9-A22D-01A_TTC13_chr1_231075132_-_JAK2_chr9_5064883_length(amino acids)=1027AA_start in transcript=31_stop in transcript=3114
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG
ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQILSPLGRIN
EAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEIELSSLREALSFVSLIDGYYRL
TADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLS
GTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGT
FTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCI
NILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATD
KWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNM
RIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKG
VCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDK
EYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCP

--------------------------------------------------------------
>In-frame_ENST00000414259_ENST00000381652_TCGA-E9-A22D-01A_TTC13_chr1_231075132_-_JAK2_chr9_5064883_length(transcript)=4507nt_BP=772nt
AAGGGCTGTCGCGCATGCGCCTTGAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGC
GGGCGCCGCCCGGCGTGTCCTGCTGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTC
GCCGCTCTCCCTGCTCAAGCAGGAGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGA
CTGGGGGGACCAGTACTCTGCCGAGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTG
TGACTCCTTGCTTTCCCTCAACACTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAA
TGACAGCACAAATGAAGAGTTAGCTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCT
TCAGATTCTGTCCCCTCTGGGACGAATTAATGAAGCAGTGAATGACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAG
ACATCGGGGAACCCTGTACTTCATATCAGAGGACTATGCAACAGCCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCC
TATAGCTATGCTATACAAAGGTTTAACTTTCTTTCACAGAGGACTTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTT
CGTGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAA
TATACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACT
TCGATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTAC
AAAAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAAC
TGTTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAA
TGGTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTT
GATATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGA
AACAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTC
TCACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGA
TACATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGA
AGAAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCAT
CAAACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGA
AAATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAG
TGCTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAA
TAATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACT
ATTAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGA
AGAGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACAC
TGGGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCT
ACAGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGG
AAGTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGA
GTATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTT
TGGGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATC
ACTGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAA
AAGTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAA
TGGAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTC
CTTTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACATGGCTGGATGAAAGAAATGACCTTCATTCTGAGACCAAAGTAGATT
TACAGAACAAAGTTTTATATTTCACATTGCTGTGGACTATTATTACATATATCATTATTATATAAATCATGATGCTAGCCAGCAAAGATG
TGAAAATATCTGCTCAAAACTTTCAAAGTTTAGTAAGTTTTTCTTCATGAGGCCACCAGTAAAAGACATTAATGAGAATTCCTTAGCAAG
GATTTTGTAAGAAGTTTCTTAAACATTGTCAGTTAACATCACTCTTGTCTGGCAAAAGAAAAAAAATAGACTTTTTCAACTCAGCTTTTT
GAGACCTGAAAAAATTATTATGTAAATTTTGCAATGTTAAAGATGCACAGAATATGTATGTATAGTTTTTACCACAGTGGATGTATAATA
CCTTGGCATCTTGTGTGATGTTTTACACACATGAGGGCTGGTGTTCATTAATACTGTTTTCTAATTTTTCCATAGTTAATCTATAATTAA
TTACTTCACTATACAAACAAATTAAGATGTTCAGATAATTGAATAAGTACCTTTGTGTCCTTGTTCATTTATATCGCTGGCCAGCATTAT
AAGCAGGTGTATACTTTTAGCTTGTAGTTCCATGTACTGTAAATATTTTTCACATAAAGGGAACAAATGTCTAGTTTTATTTGTATAGGA
AATTTCCCTGACCCTAAATAATACATTTTGAAATGAAACAAGCTTACAAAGATATAATCTATTTTATTATGGTTTCCCTTGTATCTATTT
GTGGTGAATGTGTTTTTTAAATGGAACTATCTCCAAATTTTTCTAAGACTACTATGAACAGTTTTCTTTTAAAATTTTGAGATTAAGAAT
GCCAGGAATATTGTCATCCTTTGAGCTGCTGACTGCCAATAACATTCTTCGATCTCTGGGATTTATGCTCATGAACTAAATTTAAGCTTA
AGCCATAAAATAGATTAGATTGTTTTTTAAAAATGGATAGCTCATTAAGAAGTGCAGCAGGTTAAGAATTTTTTCCTAAAGACTGTATAT
TTGAGGGGTTTCAGAATTTTGCATTGCAGTCATAGAAGAGATTTATTTCCTTTTTAGAGGGGAAATGAGGTAAATAAGTAAAAAAGTATG
CTTGTTAATTTTATTCAAGAATGCCAGTAGAAAATTCATAACGTGTATCTTTAAGAAAAATGAGCATACATCTTAAATCTTTTCAATTAA
GTATAAGGGGTTGTTCGTTGTTGTCATTTGTTATAGTGCTACTCCACTTTAGACACCATAGCTAAAATAAAATATGGTGGGTTTTGTGTG
TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTATTTATACAAAACTTAAAATACTTGCTGTTTTGATTAAAAAGAAAATAGTTTCT

>In-frame_ENST00000414259_ENST00000381652_TCGA-E9-A22D-01A_TTC13_chr1_231075132_-_JAK2_chr9_5064883_length(amino acids)=1027AA_start in transcript=31_stop in transcript=3114
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG
ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQILSPLGRIN
EAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEIELSSLREALSFVSLIDGYYRL
TADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLS
GTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGT
FTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCI
NILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATD
KWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNM
RIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKG
VCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDK
EYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCP

--------------------------------------------------------------
>In-frame_ENST00000414259_ENST00000544510_TCGA-E9-A22D-01A_TTC13_chr1_231075132_-_JAK2_chr9_5064883_length(transcript)=3173nt_BP=772nt
AAGGGCTGTCGCGCATGCGCCTTGAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGC
GGGCGCCGCCCGGCGTGTCCTGCTGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTC
GCCGCTCTCCCTGCTCAAGCAGGAGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGA
CTGGGGGGACCAGTACTCTGCCGAGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTG
TGACTCCTTGCTTTCCCTCAACACTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAA
TGACAGCACAAATGAAGAGTTAGCTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCT
TCAGATTCTGTCCCCTCTGGGACGAATTAATGAAGCAGTGAATGACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAG
ACATCGGGGAACCCTGTACTTCATATCAGAGGACTATGCAACAGCCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCC
TATAGCTATGCTATACAAAGGTTTAACTTTCTTTCACAGAGGACTTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTT
CGTGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAA
TATACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACT
TCGATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTAC
AAAAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAAC
TGTTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAA
TGGTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTT
GATATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGA
AACAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTC
TCACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGA
TACATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGA
AGAAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCAT
CAAACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGA
AAATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAG
TGCTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAA
TAATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACT
ATTAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGA
AGAGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACAC
TGGGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCT
ACAGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGG
AAGTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGA
GTATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTT
TGGGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATC
ACTGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAA
AAGTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAA
TGGAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTC
CTTTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACATGGCTGGATGAAAGAAATGACCTTCATTCTGAGACCAAAGTAGATT

>In-frame_ENST00000414259_ENST00000544510_TCGA-E9-A22D-01A_TTC13_chr1_231075132_-_JAK2_chr9_5064883_length(amino acids)=1027AA_start in transcript=31_stop in transcript=3114
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG
ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQILSPLGRIN
EAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEIELSSLREALSFVSLIDGYYRL
TADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLS
GTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGT
FTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCI
NILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATD
KWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNM
RIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKG
VCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDK
EYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCP

--------------------------------------------------------------
>In-frame_ENST00000366661_ENST00000539801_TCGA-E9-A22D_TTC13_chr1_231075131_-_JAK2_chr9_5064882_length(transcript)=3274nt_BP=908nt
GAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGGGCGCCGCCCGGCGTGTCCTGC
TGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGCCGCTCTCCCTGCTCAAGCAGG
AGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACTGGGGGGACCAGTACTCTGCCG
AGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTGACTCCTTGCTTTCCCTCAACA
CTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATGACAGCACAAATGAAGAGTTAG
CTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTCAGGAGGAGCCTGATCTGGTTA
GTGCAATTTATGGCCGAGGGATAGCCTATGGAAAGAAGGGACTACATGACATTAAGAATGCTGAGCTTGCTCTGTTCGAACTGAGCCGAG
TAATTACCTTGGAACCAGATCGTCCAGAGGTATTTGAGCAGCGAGCAGAAATTCTGTCCCCTCTGGGACGAATTAATGAAGCAGTGAATG
ACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAGACATCGGGGAACCCTGTACTTCATATCAGAGGACTATGCAACAG
CCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCCTATAGCTATGCTATACAAAGGTTTAACTTTCTTTCACAGAGGAC
TTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCGTGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCAC
ATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATATACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCA
TTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTCGATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTG
CTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAAAAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGA
ACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTGTTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTC
CCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATGGTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTA
CTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGATATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTT
TTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAACAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACT
ATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTCACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAG
ACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATACATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGA
AACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAGAAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTC
TGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCAAACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGG
ACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAAATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTG
GTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTGCTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGC
ATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATAATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAG
CCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTATTAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCC
TGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAGAGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATT
TTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTGGGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAG
AGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTACAGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTG
CTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAAGTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATC
ACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGTATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGA
GAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTGGGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAG
TAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCACTGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCT
TTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAAGTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAAC
AAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATGGAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATA
TGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCTTTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACA

>In-frame_ENST00000366661_ENST00000539801_TCGA-E9-A22D_TTC13_chr1_231075131_-_JAK2_chr9_5064882_length(amino acids)=1080AA_start in transcript=8_stop in transcript=3250
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG
ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEEPDLVSAI
YGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHE
DFQQSLELNKNQPIAMLYKGLTFFHRGLLKEIELSSLREALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISK
LKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLSGTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPK
PKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSE
SFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLI
REEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQL
PAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGS
VEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIK
LLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGV
VLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG

--------------------------------------------------------------
>In-frame_ENST00000366661_ENST00000381652_TCGA-E9-A22D_TTC13_chr1_231075131_-_JAK2_chr9_5064882_length(transcript)=4643nt_BP=908nt
GAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGGGCGCCGCCCGGCGTGTCCTGC
TGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGCCGCTCTCCCTGCTCAAGCAGG
AGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACTGGGGGGACCAGTACTCTGCCG
AGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTGACTCCTTGCTTTCCCTCAACA
CTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATGACAGCACAAATGAAGAGTTAG
CTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTCAGGAGGAGCCTGATCTGGTTA
GTGCAATTTATGGCCGAGGGATAGCCTATGGAAAGAAGGGACTACATGACATTAAGAATGCTGAGCTTGCTCTGTTCGAACTGAGCCGAG
TAATTACCTTGGAACCAGATCGTCCAGAGGTATTTGAGCAGCGAGCAGAAATTCTGTCCCCTCTGGGACGAATTAATGAAGCAGTGAATG
ACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAGACATCGGGGAACCCTGTACTTCATATCAGAGGACTATGCAACAG
CCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCCTATAGCTATGCTATACAAAGGTTTAACTTTCTTTCACAGAGGAC
TTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCGTGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCAC
ATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATATACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCA
TTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTCGATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTG
CTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAAAAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGA
ACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTGTTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTC
CCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATGGTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTA
CTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGATATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTT
TTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAACAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACT
ATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTCACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAG
ACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATACATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGA
AACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAGAAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTC
TGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCAAACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGG
ACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAAATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTG
GTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTGCTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGC
ATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATAATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAG
CCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTATTAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCC
TGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAGAGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATT
TTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTGGGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAG
AGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTACAGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTG
CTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAAGTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATC
ACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGTATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGA
GAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTGGGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAG
TAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCACTGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCT
TTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAAGTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAAC
AAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATGGAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATA
TGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCTTTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACA
TGGCTGGATGAAAGAAATGACCTTCATTCTGAGACCAAAGTAGATTTACAGAACAAAGTTTTATATTTCACATTGCTGTGGACTATTATT
ACATATATCATTATTATATAAATCATGATGCTAGCCAGCAAAGATGTGAAAATATCTGCTCAAAACTTTCAAAGTTTAGTAAGTTTTTCT
TCATGAGGCCACCAGTAAAAGACATTAATGAGAATTCCTTAGCAAGGATTTTGTAAGAAGTTTCTTAAACATTGTCAGTTAACATCACTC
TTGTCTGGCAAAAGAAAAAAAATAGACTTTTTCAACTCAGCTTTTTGAGACCTGAAAAAATTATTATGTAAATTTTGCAATGTTAAAGAT
GCACAGAATATGTATGTATAGTTTTTACCACAGTGGATGTATAATACCTTGGCATCTTGTGTGATGTTTTACACACATGAGGGCTGGTGT
TCATTAATACTGTTTTCTAATTTTTCCATAGTTAATCTATAATTAATTACTTCACTATACAAACAAATTAAGATGTTCAGATAATTGAAT
AAGTACCTTTGTGTCCTTGTTCATTTATATCGCTGGCCAGCATTATAAGCAGGTGTATACTTTTAGCTTGTAGTTCCATGTACTGTAAAT
ATTTTTCACATAAAGGGAACAAATGTCTAGTTTTATTTGTATAGGAAATTTCCCTGACCCTAAATAATACATTTTGAAATGAAACAAGCT
TACAAAGATATAATCTATTTTATTATGGTTTCCCTTGTATCTATTTGTGGTGAATGTGTTTTTTAAATGGAACTATCTCCAAATTTTTCT
AAGACTACTATGAACAGTTTTCTTTTAAAATTTTGAGATTAAGAATGCCAGGAATATTGTCATCCTTTGAGCTGCTGACTGCCAATAACA
TTCTTCGATCTCTGGGATTTATGCTCATGAACTAAATTTAAGCTTAAGCCATAAAATAGATTAGATTGTTTTTTAAAAATGGATAGCTCA
TTAAGAAGTGCAGCAGGTTAAGAATTTTTTCCTAAAGACTGTATATTTGAGGGGTTTCAGAATTTTGCATTGCAGTCATAGAAGAGATTT
ATTTCCTTTTTAGAGGGGAAATGAGGTAAATAAGTAAAAAAGTATGCTTGTTAATTTTATTCAAGAATGCCAGTAGAAAATTCATAACGT
GTATCTTTAAGAAAAATGAGCATACATCTTAAATCTTTTCAATTAAGTATAAGGGGTTGTTCGTTGTTGTCATTTGTTATAGTGCTACTC
CACTTTAGACACCATAGCTAAAATAAAATATGGTGGGTTTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTATTTATAC

>In-frame_ENST00000366661_ENST00000381652_TCGA-E9-A22D_TTC13_chr1_231075131_-_JAK2_chr9_5064882_length(amino acids)=1080AA_start in transcript=8_stop in transcript=3250
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG
ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEEPDLVSAI
YGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHE
DFQQSLELNKNQPIAMLYKGLTFFHRGLLKEIELSSLREALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISK
LKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLSGTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPK
PKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSE
SFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLI
REEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQL
PAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGS
VEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIK
LLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGV
VLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG

--------------------------------------------------------------
>In-frame_ENST00000366661_ENST00000544510_TCGA-E9-A22D_TTC13_chr1_231075131_-_JAK2_chr9_5064882_length(transcript)=3309nt_BP=908nt
GAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGGGCGCCGCCCGGCGTGTCCTGC
TGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGCCGCTCTCCCTGCTCAAGCAGG
AGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACTGGGGGGACCAGTACTCTGCCG
AGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTGACTCCTTGCTTTCCCTCAACA
CTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATGACAGCACAAATGAAGAGTTAG
CTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTCAGGAGGAGCCTGATCTGGTTA
GTGCAATTTATGGCCGAGGGATAGCCTATGGAAAGAAGGGACTACATGACATTAAGAATGCTGAGCTTGCTCTGTTCGAACTGAGCCGAG
TAATTACCTTGGAACCAGATCGTCCAGAGGTATTTGAGCAGCGAGCAGAAATTCTGTCCCCTCTGGGACGAATTAATGAAGCAGTGAATG
ACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAGACATCGGGGAACCCTGTACTTCATATCAGAGGACTATGCAACAG
CCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCCTATAGCTATGCTATACAAAGGTTTAACTTTCTTTCACAGAGGAC
TTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCGTGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCAC
ATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATATACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCA
TTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTCGATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTG
CTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAAAAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGA
ACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTGTTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTC
CCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATGGTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTA
CTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGATATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTT
TTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAACAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACT
ATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTCACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAG
ACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATACATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGA
AACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAGAAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTC
TGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCAAACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGG
ACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAAATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTG
GTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTGCTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGC
ATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATAATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAG
CCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTATTAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCC
TGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAGAGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATT
TTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTGGGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAG
AGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTACAGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTG
CTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAAGTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATC
ACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGTATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGA
GAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTGGGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAG
TAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCACTGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCT
TTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAAGTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAAC
AAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATGGAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATA
TGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCTTTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACA

>In-frame_ENST00000366661_ENST00000544510_TCGA-E9-A22D_TTC13_chr1_231075131_-_JAK2_chr9_5064882_length(amino acids)=1080AA_start in transcript=8_stop in transcript=3250
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG
ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEEPDLVSAI
YGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHE
DFQQSLELNKNQPIAMLYKGLTFFHRGLLKEIELSSLREALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISK
LKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLSGTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPK
PKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSE
SFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLI
REEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQL
PAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGS
VEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIK
LLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGV
VLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG

--------------------------------------------------------------
>In-frame_ENST00000366662_ENST00000539801_TCGA-E9-A22D_TTC13_chr1_231075131_-_JAK2_chr9_5064882_length(transcript)=3136nt_BP=770nt
GGGCTGTCGCGCATGCGCCTTGAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGG
GCGCCGCCCGGCGTGTCCTGCTGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGC
CGCTCTCCCTGCTCAAGCAGGAGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACT
GGGGGGACCAGTACTCTGCCGAGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTG
ACTCCTTGCTTTCCCTCAACACTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATG
ACAGCACAAATGAAGAGTTAGCTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTC
AGATTCTGTCCCCTCTGGGACGAATTAATGAAGCAGTGAATGACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAGAC
ATCGGGGAACCCTGTACTTCATATCAGAGGACTATGCAACAGCCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCCTA
TAGCTATGCTATACAAAGGTTTAACTTTCTTTCACAGAGGACTTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCG
TGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATA
TACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTC
GATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAA
AAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTG
TTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATG
GTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGA
TATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAA
CAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTC
ACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATA
CATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAG
AAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCA
AACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAA
ATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTG
CTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATA
ATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTAT
TAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAG
AGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTG
GGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTAC
AGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAA
GTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGT
ATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTG
GGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCAC
TGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAA
GTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATG
GAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCT

>In-frame_ENST00000366662_ENST00000539801_TCGA-E9-A22D_TTC13_chr1_231075131_-_JAK2_chr9_5064882_length(amino acids)=1027AA_start in transcript=29_stop in transcript=3112
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG
ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQILSPLGRIN
EAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEIELSSLREALSFVSLIDGYYRL
TADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLS
GTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGT
FTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCI
NILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATD
KWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNM
RIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKG
VCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDK
EYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCP

--------------------------------------------------------------
>In-frame_ENST00000366662_ENST00000381652_TCGA-E9-A22D_TTC13_chr1_231075131_-_JAK2_chr9_5064882_length(transcript)=4505nt_BP=770nt
GGGCTGTCGCGCATGCGCCTTGAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGG
GCGCCGCCCGGCGTGTCCTGCTGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGC
CGCTCTCCCTGCTCAAGCAGGAGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACT
GGGGGGACCAGTACTCTGCCGAGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTG
ACTCCTTGCTTTCCCTCAACACTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATG
ACAGCACAAATGAAGAGTTAGCTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTC
AGATTCTGTCCCCTCTGGGACGAATTAATGAAGCAGTGAATGACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAGAC
ATCGGGGAACCCTGTACTTCATATCAGAGGACTATGCAACAGCCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCCTA
TAGCTATGCTATACAAAGGTTTAACTTTCTTTCACAGAGGACTTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCG
TGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATA
TACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTC
GATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAA
AAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTG
TTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATG
GTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGA
TATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAA
CAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTC
ACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATA
CATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAG
AAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCA
AACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAA
ATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTG
CTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATA
ATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTAT
TAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAG
AGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTG
GGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTAC
AGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAA
GTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGT
ATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTG
GGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCAC
TGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAA
GTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATG
GAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCT
TTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACATGGCTGGATGAAAGAAATGACCTTCATTCTGAGACCAAAGTAGATTTA
CAGAACAAAGTTTTATATTTCACATTGCTGTGGACTATTATTACATATATCATTATTATATAAATCATGATGCTAGCCAGCAAAGATGTG
AAAATATCTGCTCAAAACTTTCAAAGTTTAGTAAGTTTTTCTTCATGAGGCCACCAGTAAAAGACATTAATGAGAATTCCTTAGCAAGGA
TTTTGTAAGAAGTTTCTTAAACATTGTCAGTTAACATCACTCTTGTCTGGCAAAAGAAAAAAAATAGACTTTTTCAACTCAGCTTTTTGA
GACCTGAAAAAATTATTATGTAAATTTTGCAATGTTAAAGATGCACAGAATATGTATGTATAGTTTTTACCACAGTGGATGTATAATACC
TTGGCATCTTGTGTGATGTTTTACACACATGAGGGCTGGTGTTCATTAATACTGTTTTCTAATTTTTCCATAGTTAATCTATAATTAATT
ACTTCACTATACAAACAAATTAAGATGTTCAGATAATTGAATAAGTACCTTTGTGTCCTTGTTCATTTATATCGCTGGCCAGCATTATAA
GCAGGTGTATACTTTTAGCTTGTAGTTCCATGTACTGTAAATATTTTTCACATAAAGGGAACAAATGTCTAGTTTTATTTGTATAGGAAA
TTTCCCTGACCCTAAATAATACATTTTGAAATGAAACAAGCTTACAAAGATATAATCTATTTTATTATGGTTTCCCTTGTATCTATTTGT
GGTGAATGTGTTTTTTAAATGGAACTATCTCCAAATTTTTCTAAGACTACTATGAACAGTTTTCTTTTAAAATTTTGAGATTAAGAATGC
CAGGAATATTGTCATCCTTTGAGCTGCTGACTGCCAATAACATTCTTCGATCTCTGGGATTTATGCTCATGAACTAAATTTAAGCTTAAG
CCATAAAATAGATTAGATTGTTTTTTAAAAATGGATAGCTCATTAAGAAGTGCAGCAGGTTAAGAATTTTTTCCTAAAGACTGTATATTT
GAGGGGTTTCAGAATTTTGCATTGCAGTCATAGAAGAGATTTATTTCCTTTTTAGAGGGGAAATGAGGTAAATAAGTAAAAAAGTATGCT
TGTTAATTTTATTCAAGAATGCCAGTAGAAAATTCATAACGTGTATCTTTAAGAAAAATGAGCATACATCTTAAATCTTTTCAATTAAGT
ATAAGGGGTTGTTCGTTGTTGTCATTTGTTATAGTGCTACTCCACTTTAGACACCATAGCTAAAATAAAATATGGTGGGTTTTGTGTGTG
TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTATTTATACAAAACTTAAAATACTTGCTGTTTTGATTAAAAAGAAAATAGTTTCTTA

>In-frame_ENST00000366662_ENST00000381652_TCGA-E9-A22D_TTC13_chr1_231075131_-_JAK2_chr9_5064882_length(amino acids)=1027AA_start in transcript=29_stop in transcript=3112
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG
ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQILSPLGRIN
EAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEIELSSLREALSFVSLIDGYYRL
TADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLS
GTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGT
FTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCI
NILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATD
KWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNM
RIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKG
VCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDK
EYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCP

--------------------------------------------------------------
>In-frame_ENST00000366662_ENST00000544510_TCGA-E9-A22D_TTC13_chr1_231075131_-_JAK2_chr9_5064882_length(transcript)=3171nt_BP=770nt
GGGCTGTCGCGCATGCGCCTTGAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGG
GCGCCGCCCGGCGTGTCCTGCTGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGC
CGCTCTCCCTGCTCAAGCAGGAGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACT
GGGGGGACCAGTACTCTGCCGAGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTG
ACTCCTTGCTTTCCCTCAACACTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATG
ACAGCACAAATGAAGAGTTAGCTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTC
AGATTCTGTCCCCTCTGGGACGAATTAATGAAGCAGTGAATGACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAGAC
ATCGGGGAACCCTGTACTTCATATCAGAGGACTATGCAACAGCCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCCTA
TAGCTATGCTATACAAAGGTTTAACTTTCTTTCACAGAGGACTTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCG
TGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATA
TACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTC
GATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAA
AAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTG
TTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATG
GTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGA
TATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAA
CAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTC
ACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATA
CATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAG
AAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCA
AACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAA
ATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTG
CTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATA
ATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTAT
TAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAG
AGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTG
GGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTAC
AGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAA
GTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGT
ATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTG
GGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCAC
TGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAA
GTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATG
GAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCT
TTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACATGGCTGGATGAAAGAAATGACCTTCATTCTGAGACCAAAGTAGATTTA

>In-frame_ENST00000366662_ENST00000544510_TCGA-E9-A22D_TTC13_chr1_231075131_-_JAK2_chr9_5064882_length(amino acids)=1027AA_start in transcript=29_stop in transcript=3112
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG
ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQILSPLGRIN
EAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEIELSSLREALSFVSLIDGYYRL
TADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLS
GTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGT
FTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCI
NILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATD
KWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNM
RIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKG
VCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDK
EYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCP

--------------------------------------------------------------
>In-frame_ENST00000414259_ENST00000539801_TCGA-E9-A22D_TTC13_chr1_231075131_-_JAK2_chr9_5064882_length(transcript)=3138nt_BP=772nt
AAGGGCTGTCGCGCATGCGCCTTGAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGC
GGGCGCCGCCCGGCGTGTCCTGCTGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTC
GCCGCTCTCCCTGCTCAAGCAGGAGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGA
CTGGGGGGACCAGTACTCTGCCGAGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTG
TGACTCCTTGCTTTCCCTCAACACTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAA
TGACAGCACAAATGAAGAGTTAGCTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCT
TCAGATTCTGTCCCCTCTGGGACGAATTAATGAAGCAGTGAATGACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAG
ACATCGGGGAACCCTGTACTTCATATCAGAGGACTATGCAACAGCCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCC
TATAGCTATGCTATACAAAGGTTTAACTTTCTTTCACAGAGGACTTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTT
CGTGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAA
TATACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACT
TCGATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTAC
AAAAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAAC
TGTTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAA
TGGTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTT
GATATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGA
AACAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTC
TCACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGA
TACATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGA
AGAAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCAT
CAAACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGA
AAATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAG
TGCTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAA
TAATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACT
ATTAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGA
AGAGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACAC
TGGGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCT
ACAGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGG
AAGTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGA
GTATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTT
TGGGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATC
ACTGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAA
AAGTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAA
TGGAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTC

>In-frame_ENST00000414259_ENST00000539801_TCGA-E9-A22D_TTC13_chr1_231075131_-_JAK2_chr9_5064882_length(amino acids)=1027AA_start in transcript=31_stop in transcript=3114
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG
ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQILSPLGRIN
EAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEIELSSLREALSFVSLIDGYYRL
TADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLS
GTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGT
FTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCI
NILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATD
KWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNM
RIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKG
VCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDK
EYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCP

--------------------------------------------------------------
>In-frame_ENST00000414259_ENST00000381652_TCGA-E9-A22D_TTC13_chr1_231075131_-_JAK2_chr9_5064882_length(transcript)=4507nt_BP=772nt
AAGGGCTGTCGCGCATGCGCCTTGAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGC
GGGCGCCGCCCGGCGTGTCCTGCTGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTC
GCCGCTCTCCCTGCTCAAGCAGGAGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGA
CTGGGGGGACCAGTACTCTGCCGAGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTG
TGACTCCTTGCTTTCCCTCAACACTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAA
TGACAGCACAAATGAAGAGTTAGCTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCT
TCAGATTCTGTCCCCTCTGGGACGAATTAATGAAGCAGTGAATGACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAG
ACATCGGGGAACCCTGTACTTCATATCAGAGGACTATGCAACAGCCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCC
TATAGCTATGCTATACAAAGGTTTAACTTTCTTTCACAGAGGACTTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTT
CGTGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAA
TATACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACT
TCGATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTAC
AAAAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAAC
TGTTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAA
TGGTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTT
GATATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGA
AACAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTC
TCACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGA
TACATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGA
AGAAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCAT
CAAACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGA
AAATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAG
TGCTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAA
TAATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACT
ATTAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGA
AGAGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACAC
TGGGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCT
ACAGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGG
AAGTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGA
GTATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTT
TGGGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATC
ACTGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAA
AAGTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAA
TGGAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTC
CTTTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACATGGCTGGATGAAAGAAATGACCTTCATTCTGAGACCAAAGTAGATT
TACAGAACAAAGTTTTATATTTCACATTGCTGTGGACTATTATTACATATATCATTATTATATAAATCATGATGCTAGCCAGCAAAGATG
TGAAAATATCTGCTCAAAACTTTCAAAGTTTAGTAAGTTTTTCTTCATGAGGCCACCAGTAAAAGACATTAATGAGAATTCCTTAGCAAG
GATTTTGTAAGAAGTTTCTTAAACATTGTCAGTTAACATCACTCTTGTCTGGCAAAAGAAAAAAAATAGACTTTTTCAACTCAGCTTTTT
GAGACCTGAAAAAATTATTATGTAAATTTTGCAATGTTAAAGATGCACAGAATATGTATGTATAGTTTTTACCACAGTGGATGTATAATA
CCTTGGCATCTTGTGTGATGTTTTACACACATGAGGGCTGGTGTTCATTAATACTGTTTTCTAATTTTTCCATAGTTAATCTATAATTAA
TTACTTCACTATACAAACAAATTAAGATGTTCAGATAATTGAATAAGTACCTTTGTGTCCTTGTTCATTTATATCGCTGGCCAGCATTAT
AAGCAGGTGTATACTTTTAGCTTGTAGTTCCATGTACTGTAAATATTTTTCACATAAAGGGAACAAATGTCTAGTTTTATTTGTATAGGA
AATTTCCCTGACCCTAAATAATACATTTTGAAATGAAACAAGCTTACAAAGATATAATCTATTTTATTATGGTTTCCCTTGTATCTATTT
GTGGTGAATGTGTTTTTTAAATGGAACTATCTCCAAATTTTTCTAAGACTACTATGAACAGTTTTCTTTTAAAATTTTGAGATTAAGAAT
GCCAGGAATATTGTCATCCTTTGAGCTGCTGACTGCCAATAACATTCTTCGATCTCTGGGATTTATGCTCATGAACTAAATTTAAGCTTA
AGCCATAAAATAGATTAGATTGTTTTTTAAAAATGGATAGCTCATTAAGAAGTGCAGCAGGTTAAGAATTTTTTCCTAAAGACTGTATAT
TTGAGGGGTTTCAGAATTTTGCATTGCAGTCATAGAAGAGATTTATTTCCTTTTTAGAGGGGAAATGAGGTAAATAAGTAAAAAAGTATG
CTTGTTAATTTTATTCAAGAATGCCAGTAGAAAATTCATAACGTGTATCTTTAAGAAAAATGAGCATACATCTTAAATCTTTTCAATTAA
GTATAAGGGGTTGTTCGTTGTTGTCATTTGTTATAGTGCTACTCCACTTTAGACACCATAGCTAAAATAAAATATGGTGGGTTTTGTGTG
TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTATTTATACAAAACTTAAAATACTTGCTGTTTTGATTAAAAAGAAAATAGTTTCT

>In-frame_ENST00000414259_ENST00000381652_TCGA-E9-A22D_TTC13_chr1_231075131_-_JAK2_chr9_5064882_length(amino acids)=1027AA_start in transcript=31_stop in transcript=3114
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG
ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQILSPLGRIN
EAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEIELSSLREALSFVSLIDGYYRL
TADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLS
GTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGT
FTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCI
NILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATD
KWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNM
RIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKG
VCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDK
EYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCP

--------------------------------------------------------------
>In-frame_ENST00000414259_ENST00000544510_TCGA-E9-A22D_TTC13_chr1_231075131_-_JAK2_chr9_5064882_length(transcript)=3173nt_BP=772nt
AAGGGCTGTCGCGCATGCGCCTTGAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGC
GGGCGCCGCCCGGCGTGTCCTGCTGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTC
GCCGCTCTCCCTGCTCAAGCAGGAGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGA
CTGGGGGGACCAGTACTCTGCCGAGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTG
TGACTCCTTGCTTTCCCTCAACACTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAA
TGACAGCACAAATGAAGAGTTAGCTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCT
TCAGATTCTGTCCCCTCTGGGACGAATTAATGAAGCAGTGAATGACCTCACTAAAGCTATCCAACTGCAGCCCTCAGCACGGCTGTACAG
ACATCGGGGAACCCTGTACTTCATATCAGAGGACTATGCAACAGCCCATGAAGACTTTCAGCAGTCCTTAGAACTGAACAAAAACCAGCC
TATAGCTATGCTATACAAAGGTTTAACTTTCTTTCACAGAGGACTTCTGAAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTT
CGTGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAA
TATACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACT
TCGATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTAC
AAAAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAAC
TGTTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAA
TGGTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTT
GATATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGA
AACAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTC
TCACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGA
TACATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGA
AGAAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCAT
CAAACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGA
AAATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAG
TGCTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAA
TAATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACT
ATTAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGA
AGAGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACAC
TGGGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCT
ACAGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGG
AAGTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGA
GTATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTT
TGGGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATC
ACTGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAA
AAGTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAA
TGGAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTC
CTTTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACATGGCTGGATGAAAGAAATGACCTTCATTCTGAGACCAAAGTAGATT

>In-frame_ENST00000414259_ENST00000544510_TCGA-E9-A22D_TTC13_chr1_231075131_-_JAK2_chr9_5064882_length(amino acids)=1027AA_start in transcript=31_stop in transcript=3114
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG
ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQILSPLGRIN
EAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEIELSSLREALSFVSLIDGYYRL
TADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLS
GTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGT
FTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCI
NILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATD
KWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNM
RIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKG
VCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDK
EYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCP

--------------------------------------------------------------
>In-frame_ENST00000366661_ENST00000539801_TCGA-E9-A22D-01A_TTC13_chr1_231079552_-_JAK2_chr9_5064883_length(transcript)=3046nt_BP=680nt
GAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGGGCGCCGCCCGGCGTGTCCTGC
TGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGCCGCTCTCCCTGCTCAAGCAGG
AGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACTGGGGGGACCAGTACTCTGCCG
AGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTGACTCCTTGCTTTCCCTCAACA
CTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATGACAGCACAAATGAAGAGTTAG
CTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTCAGGAGGAGCCTGATCTGGTTA
GTGCAATTTATGGCCGAGGGATAGCCTATGGAAAGAAGGGACTACATGACATTAAGAATGCTGAGCTTGCTCTGTTCGAACTGAGCCGAG
TAATTACCTTGGAACCAGATCGTCCAGAGGTATTTGAGCAGCGAGCAGAAGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCG
TGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATA
TACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTC
GATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAA
AAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTG
TTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATG
GTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGA
TATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAA
CAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTC
ACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATA
CATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAG
AAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCA
AACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAA
ATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTG
CTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATA
ATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTAT
TAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAG
AGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTG
GGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTAC
AGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAA
GTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGT
ATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTG
GGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCAC
TGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAA
GTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATG
GAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCT

>In-frame_ENST00000366661_ENST00000539801_TCGA-E9-A22D-01A_TTC13_chr1_231079552_-_JAK2_chr9_5064883_length(amino acids)=1004AA_start in transcript=8_stop in transcript=3022
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG
ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEEPDLVSAI
YGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRPEVFEQRAEEIELSSLREALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIQS
NCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLSGTKKNFSSLKDLLNCYQMETVRS
DNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEV
LLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMHFLEENT
LIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALD
SQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDPTQFEERH
LKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLR
DYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTE
SKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRD

--------------------------------------------------------------
>In-frame_ENST00000366661_ENST00000381652_TCGA-E9-A22D-01A_TTC13_chr1_231079552_-_JAK2_chr9_5064883_length(transcript)=4415nt_BP=680nt
GAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGGGCGCCGCCCGGCGTGTCCTGC
TGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGCCGCTCTCCCTGCTCAAGCAGG
AGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACTGGGGGGACCAGTACTCTGCCG
AGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTGACTCCTTGCTTTCCCTCAACA
CTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATGACAGCACAAATGAAGAGTTAG
CTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTCAGGAGGAGCCTGATCTGGTTA
GTGCAATTTATGGCCGAGGGATAGCCTATGGAAAGAAGGGACTACATGACATTAAGAATGCTGAGCTTGCTCTGTTCGAACTGAGCCGAG
TAATTACCTTGGAACCAGATCGTCCAGAGGTATTTGAGCAGCGAGCAGAAGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCG
TGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATA
TACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTC
GATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAA
AAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTG
TTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATG
GTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGA
TATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAA
CAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTC
ACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATA
CATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAG
AAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCA
AACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAA
ATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTG
CTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATA
ATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTAT
TAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAG
AGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTG
GGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTAC
AGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAA
GTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGT
ATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTG
GGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCAC
TGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAA
GTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATG
GAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCT
TTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACATGGCTGGATGAAAGAAATGACCTTCATTCTGAGACCAAAGTAGATTTA
CAGAACAAAGTTTTATATTTCACATTGCTGTGGACTATTATTACATATATCATTATTATATAAATCATGATGCTAGCCAGCAAAGATGTG
AAAATATCTGCTCAAAACTTTCAAAGTTTAGTAAGTTTTTCTTCATGAGGCCACCAGTAAAAGACATTAATGAGAATTCCTTAGCAAGGA
TTTTGTAAGAAGTTTCTTAAACATTGTCAGTTAACATCACTCTTGTCTGGCAAAAGAAAAAAAATAGACTTTTTCAACTCAGCTTTTTGA
GACCTGAAAAAATTATTATGTAAATTTTGCAATGTTAAAGATGCACAGAATATGTATGTATAGTTTTTACCACAGTGGATGTATAATACC
TTGGCATCTTGTGTGATGTTTTACACACATGAGGGCTGGTGTTCATTAATACTGTTTTCTAATTTTTCCATAGTTAATCTATAATTAATT
ACTTCACTATACAAACAAATTAAGATGTTCAGATAATTGAATAAGTACCTTTGTGTCCTTGTTCATTTATATCGCTGGCCAGCATTATAA
GCAGGTGTATACTTTTAGCTTGTAGTTCCATGTACTGTAAATATTTTTCACATAAAGGGAACAAATGTCTAGTTTTATTTGTATAGGAAA
TTTCCCTGACCCTAAATAATACATTTTGAAATGAAACAAGCTTACAAAGATATAATCTATTTTATTATGGTTTCCCTTGTATCTATTTGT
GGTGAATGTGTTTTTTAAATGGAACTATCTCCAAATTTTTCTAAGACTACTATGAACAGTTTTCTTTTAAAATTTTGAGATTAAGAATGC
CAGGAATATTGTCATCCTTTGAGCTGCTGACTGCCAATAACATTCTTCGATCTCTGGGATTTATGCTCATGAACTAAATTTAAGCTTAAG
CCATAAAATAGATTAGATTGTTTTTTAAAAATGGATAGCTCATTAAGAAGTGCAGCAGGTTAAGAATTTTTTCCTAAAGACTGTATATTT
GAGGGGTTTCAGAATTTTGCATTGCAGTCATAGAAGAGATTTATTTCCTTTTTAGAGGGGAAATGAGGTAAATAAGTAAAAAAGTATGCT
TGTTAATTTTATTCAAGAATGCCAGTAGAAAATTCATAACGTGTATCTTTAAGAAAAATGAGCATACATCTTAAATCTTTTCAATTAAGT
ATAAGGGGTTGTTCGTTGTTGTCATTTGTTATAGTGCTACTCCACTTTAGACACCATAGCTAAAATAAAATATGGTGGGTTTTGTGTGTG
TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTATTTATACAAAACTTAAAATACTTGCTGTTTTGATTAAAAAGAAAATAGTTTCTTA

>In-frame_ENST00000366661_ENST00000381652_TCGA-E9-A22D-01A_TTC13_chr1_231079552_-_JAK2_chr9_5064883_length(amino acids)=1004AA_start in transcript=8_stop in transcript=3022
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG
ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEEPDLVSAI
YGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRPEVFEQRAEEIELSSLREALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIQS
NCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLSGTKKNFSSLKDLLNCYQMETVRS
DNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEV
LLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMHFLEENT
LIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALD
SQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDPTQFEERH
LKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLR
DYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTE
SKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRD

--------------------------------------------------------------
>In-frame_ENST00000366661_ENST00000544510_TCGA-E9-A22D-01A_TTC13_chr1_231079552_-_JAK2_chr9_5064883_length(transcript)=3081nt_BP=680nt
GAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGGGCGCCGCCCGGCGTGTCCTGC
TGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGCCGCTCTCCCTGCTCAAGCAGG
AGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACTGGGGGGACCAGTACTCTGCCG
AGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTGACTCCTTGCTTTCCCTCAACA
CTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATGACAGCACAAATGAAGAGTTAG
CTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTCAGGAGGAGCCTGATCTGGTTA
GTGCAATTTATGGCCGAGGGATAGCCTATGGAAAGAAGGGACTACATGACATTAAGAATGCTGAGCTTGCTCTGTTCGAACTGAGCCGAG
TAATTACCTTGGAACCAGATCGTCCAGAGGTATTTGAGCAGCGAGCAGAAGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCG
TGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCATTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATA
TACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAGTAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTC
GATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGTCGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAA
AAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTTCAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTG
TTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCCAAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATG
GTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCATATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGA
TATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAAAGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAA
CAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTCAGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTC
ACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGAGAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATA
CATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACTTGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAG
AAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCTTATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCA
AACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACATTCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAA
ATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTACCACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTG
CTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCAGCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATA
ATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCATCATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTAT
TAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGGGTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAG
AGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGGGAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTG
GGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCACCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTAC
AGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGGTCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAA
GTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACATAAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGT
ATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAATATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTG
GGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAAAGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCAC
TGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGGAGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAA
GTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGGACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATG
GAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGATCATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCT
TTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACATGGCTGGATGAAAGAAATGACCTTCATTCTGAGACCAAAGTAGATTTA

>In-frame_ENST00000366661_ENST00000544510_TCGA-E9-A22D-01A_TTC13_chr1_231079552_-_JAK2_chr9_5064883_length(amino acids)=1004AA_start in transcript=8_stop in transcript=3022
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG
ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEEPDLVSAI
YGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRPEVFEQRAEEIELSSLREALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIQS
NCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLSGTKKNFSSLKDLLNCYQMETVRS
DNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEV
LLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMHFLEENT
LIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALD
SQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDPTQFEERH
LKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLR
DYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTE
SKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRD

--------------------------------------------------------------
>In-frame_ENST00000366661_ENST00000539801_TCGA-E9-A22D-01A_TTC13_chr1_231090079_-_JAK2_chr9_5064883_length(transcript)=2887nt_BP=521nt
GAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGGGCGCCGCCCGGCGTGTCCTGC
TGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGCCGCTCTCCCTGCTCAAGCAGG
AGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACTGGGGGGACCAGTACTCTGCCG
AGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTGACTCCTTGCTTTCCCTCAACA
CTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATGACAGCACAAATGAAGAGTTAG
CTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTCAGGAAATTGAACTTAGCTCAT
TAAGGGAAGCTTTGTCTTTCGTGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCATTACCTCTGTAAAGAAGTAGCAC
CTCCAGCCGTGCTTGAAAATATACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAGTAAACTGAAGAAAGCAGGTAATC
AGACTGGACTGTATGTACTTCGATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGTCGAGCGAGAAAATGTCATTGAAT
ATAAACACTGTTTGATTACAAAAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTTCAGCAGTCTTAAAGATCTTTTGA
ATTGTTACCAGATGGAAACTGTTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCCAAAGCCAAAAGATAAATCAAACC
TTCTAGTCTTCAGAACGAATGGTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCATATGAACCAAATGGTGTTTCACA
AAATCAGAAATGAAGATTTGATATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAAAGGCGTACGAAGAGAAGTAGGAG
ACTACGGTCAACTGCATGAAACAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTCAGAGTCTTTCTTTGAAGCAGCAA
GTATGATGAGCAAGCTTTCTCACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGAGAATATTCTGGTTCAGGAGTTTG
TAAAATTTGGATCACTAGATACATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACTTGAAGTTGCTAAACAGTTGGCAT
GGGCCATGCATTTTCTAGAAGAAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCTTATCAGAGAAGAAGACAGGAAGA
CAGGAAATCCTCCTTTCATCAAACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACATTCTTCAGGAGAGAATACCATGGG
TACCACCTGAATGCATTGAAAATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTACCACTTTGTGGGAAATCTGCAGTG
GAGGAGATAAACCTCTAAGTGCTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCAGCTTCCTGCACCAAAGTGGGCAG
AATTAGCAAACCTTATAAATAATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCATCATACGAGATCTTAACAGTTTGT
TTACTCCAGATTATGAACTATTAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGGGTTTTCTGGTGCCTTTGAAGACC
GGGATCCTACACAGTTTGAAGAGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGGGAGTGTGGAGATGTGCCGGTATG
ACCCTCTACAGGACAACACTGGGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCACCTAAGAGACTTTGAAAGGGAAA
TTGAAATCCTGAAATCCCTACAGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGGTCGGCGTAATCTAAAATTAATTA
TGGAATATTTACCATATGGAAGTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACATAAAACTTCTGCAGTACACATCTC
AGATATGCAAGGGTATGGAGTATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAATATATTGGTGGAGAACGAGAACA
GAGTTAAAATTGGAGATTTTGGGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAAAGAACCTGGTGAAAGTCCCATAT
TCTGGTATGCTCCAGAATCACTGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGGAGTGGTTCTGTATGAACTTTTCA
CATACATTGAGAAGAGTAAAAGTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGGACAGATGATCGTGTTCCATTTGA
TAGAACTTTTGAAGAATAATGGAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGATCATGACAGAATGCTGGAACAATA
ATGTAAATCAACGCCCCTCCTTTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACATGGCTGGATGAAAGAAATGACCTTCAT

>In-frame_ENST00000366661_ENST00000539801_TCGA-E9-A22D-01A_TTC13_chr1_231090079_-_JAK2_chr9_5064883_length(amino acids)=951AA_start in transcript=8_stop in transcript=2863
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG
ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEIELSSLRE
ALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKH
CLITKNENEEYNLSGTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIR
NEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKF
GSLDTYLKKNKNCINILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPP
ECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTP
DYELLTENDMLPNMRIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEI
LKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVK
IGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIEL

--------------------------------------------------------------
>In-frame_ENST00000366661_ENST00000381652_TCGA-E9-A22D-01A_TTC13_chr1_231090079_-_JAK2_chr9_5064883_length(transcript)=4256nt_BP=521nt
GAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGGGCGCCGCCCGGCGTGTCCTGC
TGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGCCGCTCTCCCTGCTCAAGCAGG
AGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACTGGGGGGACCAGTACTCTGCCG
AGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTGACTCCTTGCTTTCCCTCAACA
CTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATGACAGCACAAATGAAGAGTTAG
CTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTCAGGAAATTGAACTTAGCTCAT
TAAGGGAAGCTTTGTCTTTCGTGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCATTACCTCTGTAAAGAAGTAGCAC
CTCCAGCCGTGCTTGAAAATATACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAGTAAACTGAAGAAAGCAGGTAATC
AGACTGGACTGTATGTACTTCGATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGTCGAGCGAGAAAATGTCATTGAAT
ATAAACACTGTTTGATTACAAAAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTTCAGCAGTCTTAAAGATCTTTTGA
ATTGTTACCAGATGGAAACTGTTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCCAAAGCCAAAAGATAAATCAAACC
TTCTAGTCTTCAGAACGAATGGTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCATATGAACCAAATGGTGTTTCACA
AAATCAGAAATGAAGATTTGATATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAAAGGCGTACGAAGAGAAGTAGGAG
ACTACGGTCAACTGCATGAAACAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTCAGAGTCTTTCTTTGAAGCAGCAA
GTATGATGAGCAAGCTTTCTCACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGAGAATATTCTGGTTCAGGAGTTTG
TAAAATTTGGATCACTAGATACATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACTTGAAGTTGCTAAACAGTTGGCAT
GGGCCATGCATTTTCTAGAAGAAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCTTATCAGAGAAGAAGACAGGAAGA
CAGGAAATCCTCCTTTCATCAAACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACATTCTTCAGGAGAGAATACCATGGG
TACCACCTGAATGCATTGAAAATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTACCACTTTGTGGGAAATCTGCAGTG
GAGGAGATAAACCTCTAAGTGCTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCAGCTTCCTGCACCAAAGTGGGCAG
AATTAGCAAACCTTATAAATAATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCATCATACGAGATCTTAACAGTTTGT
TTACTCCAGATTATGAACTATTAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGGGTTTTCTGGTGCCTTTGAAGACC
GGGATCCTACACAGTTTGAAGAGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGGGAGTGTGGAGATGTGCCGGTATG
ACCCTCTACAGGACAACACTGGGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCACCTAAGAGACTTTGAAAGGGAAA
TTGAAATCCTGAAATCCCTACAGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGGTCGGCGTAATCTAAAATTAATTA
TGGAATATTTACCATATGGAAGTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACATAAAACTTCTGCAGTACACATCTC
AGATATGCAAGGGTATGGAGTATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAATATATTGGTGGAGAACGAGAACA
GAGTTAAAATTGGAGATTTTGGGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAAAGAACCTGGTGAAAGTCCCATAT
TCTGGTATGCTCCAGAATCACTGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGGAGTGGTTCTGTATGAACTTTTCA
CATACATTGAGAAGAGTAAAAGTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGGACAGATGATCGTGTTCCATTTGA
TAGAACTTTTGAAGAATAATGGAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGATCATGACAGAATGCTGGAACAATA
ATGTAAATCAACGCCCCTCCTTTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACATGGCTGGATGAAAGAAATGACCTTCAT
TCTGAGACCAAAGTAGATTTACAGAACAAAGTTTTATATTTCACATTGCTGTGGACTATTATTACATATATCATTATTATATAAATCATG
ATGCTAGCCAGCAAAGATGTGAAAATATCTGCTCAAAACTTTCAAAGTTTAGTAAGTTTTTCTTCATGAGGCCACCAGTAAAAGACATTA
ATGAGAATTCCTTAGCAAGGATTTTGTAAGAAGTTTCTTAAACATTGTCAGTTAACATCACTCTTGTCTGGCAAAAGAAAAAAAATAGAC
TTTTTCAACTCAGCTTTTTGAGACCTGAAAAAATTATTATGTAAATTTTGCAATGTTAAAGATGCACAGAATATGTATGTATAGTTTTTA
CCACAGTGGATGTATAATACCTTGGCATCTTGTGTGATGTTTTACACACATGAGGGCTGGTGTTCATTAATACTGTTTTCTAATTTTTCC
ATAGTTAATCTATAATTAATTACTTCACTATACAAACAAATTAAGATGTTCAGATAATTGAATAAGTACCTTTGTGTCCTTGTTCATTTA
TATCGCTGGCCAGCATTATAAGCAGGTGTATACTTTTAGCTTGTAGTTCCATGTACTGTAAATATTTTTCACATAAAGGGAACAAATGTC
TAGTTTTATTTGTATAGGAAATTTCCCTGACCCTAAATAATACATTTTGAAATGAAACAAGCTTACAAAGATATAATCTATTTTATTATG
GTTTCCCTTGTATCTATTTGTGGTGAATGTGTTTTTTAAATGGAACTATCTCCAAATTTTTCTAAGACTACTATGAACAGTTTTCTTTTA
AAATTTTGAGATTAAGAATGCCAGGAATATTGTCATCCTTTGAGCTGCTGACTGCCAATAACATTCTTCGATCTCTGGGATTTATGCTCA
TGAACTAAATTTAAGCTTAAGCCATAAAATAGATTAGATTGTTTTTTAAAAATGGATAGCTCATTAAGAAGTGCAGCAGGTTAAGAATTT
TTTCCTAAAGACTGTATATTTGAGGGGTTTCAGAATTTTGCATTGCAGTCATAGAAGAGATTTATTTCCTTTTTAGAGGGGAAATGAGGT
AAATAAGTAAAAAAGTATGCTTGTTAATTTTATTCAAGAATGCCAGTAGAAAATTCATAACGTGTATCTTTAAGAAAAATGAGCATACAT
CTTAAATCTTTTCAATTAAGTATAAGGGGTTGTTCGTTGTTGTCATTTGTTATAGTGCTACTCCACTTTAGACACCATAGCTAAAATAAA
ATATGGTGGGTTTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTATTTATACAAAACTTAAAATACTTGCTGTTTTGAT

>In-frame_ENST00000366661_ENST00000381652_TCGA-E9-A22D-01A_TTC13_chr1_231090079_-_JAK2_chr9_5064883_length(amino acids)=951AA_start in transcript=8_stop in transcript=2863
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG
ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEIELSSLRE
ALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKH
CLITKNENEEYNLSGTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIR
NEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKF
GSLDTYLKKNKNCINILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPP
ECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTP
DYELLTENDMLPNMRIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEI
LKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVK
IGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIEL

--------------------------------------------------------------
>In-frame_ENST00000366661_ENST00000544510_TCGA-E9-A22D-01A_TTC13_chr1_231090079_-_JAK2_chr9_5064883_length(transcript)=2922nt_BP=521nt
GAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGGGCGCCGCCCGGCGTGTCCTGC
TGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGCCGCTCTCCCTGCTCAAGCAGG
AGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACTGGGGGGACCAGTACTCTGCCG
AGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTGACTCCTTGCTTTCCCTCAACA
CTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATGACAGCACAAATGAAGAGTTAG
CTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTCAGGAAATTGAACTTAGCTCAT
TAAGGGAAGCTTTGTCTTTCGTGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCATTACCTCTGTAAAGAAGTAGCAC
CTCCAGCCGTGCTTGAAAATATACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAGTAAACTGAAGAAAGCAGGTAATC
AGACTGGACTGTATGTACTTCGATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGTCGAGCGAGAAAATGTCATTGAAT
ATAAACACTGTTTGATTACAAAAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTTCAGCAGTCTTAAAGATCTTTTGA
ATTGTTACCAGATGGAAACTGTTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCCAAAGCCAAAAGATAAATCAAACC
TTCTAGTCTTCAGAACGAATGGTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCATATGAACCAAATGGTGTTTCACA
AAATCAGAAATGAAGATTTGATATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAAAGGCGTACGAAGAGAAGTAGGAG
ACTACGGTCAACTGCATGAAACAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTCAGAGTCTTTCTTTGAAGCAGCAA
GTATGATGAGCAAGCTTTCTCACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGAGAATATTCTGGTTCAGGAGTTTG
TAAAATTTGGATCACTAGATACATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACTTGAAGTTGCTAAACAGTTGGCAT
GGGCCATGCATTTTCTAGAAGAAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCTTATCAGAGAAGAAGACAGGAAGA
CAGGAAATCCTCCTTTCATCAAACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACATTCTTCAGGAGAGAATACCATGGG
TACCACCTGAATGCATTGAAAATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTACCACTTTGTGGGAAATCTGCAGTG
GAGGAGATAAACCTCTAAGTGCTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCAGCTTCCTGCACCAAAGTGGGCAG
AATTAGCAAACCTTATAAATAATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCATCATACGAGATCTTAACAGTTTGT
TTACTCCAGATTATGAACTATTAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGGGTTTTCTGGTGCCTTTGAAGACC
GGGATCCTACACAGTTTGAAGAGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGGGAGTGTGGAGATGTGCCGGTATG
ACCCTCTACAGGACAACACTGGGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCACCTAAGAGACTTTGAAAGGGAAA
TTGAAATCCTGAAATCCCTACAGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGGTCGGCGTAATCTAAAATTAATTA
TGGAATATTTACCATATGGAAGTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACATAAAACTTCTGCAGTACACATCTC
AGATATGCAAGGGTATGGAGTATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAATATATTGGTGGAGAACGAGAACA
GAGTTAAAATTGGAGATTTTGGGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAAAGAACCTGGTGAAAGTCCCATAT
TCTGGTATGCTCCAGAATCACTGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGGAGTGGTTCTGTATGAACTTTTCA
CATACATTGAGAAGAGTAAAAGTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGGACAGATGATCGTGTTCCATTTGA
TAGAACTTTTGAAGAATAATGGAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGATCATGACAGAATGCTGGAACAATA
ATGTAAATCAACGCCCCTCCTTTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACATGGCTGGATGAAAGAAATGACCTTCAT

>In-frame_ENST00000366661_ENST00000544510_TCGA-E9-A22D-01A_TTC13_chr1_231090079_-_JAK2_chr9_5064883_length(amino acids)=951AA_start in transcript=8_stop in transcript=2863
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG
ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEIELSSLRE
ALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKH
CLITKNENEEYNLSGTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIR
NEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKF
GSLDTYLKKNKNCINILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPP
ECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTP
DYELLTENDMLPNMRIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEI
LKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVK
IGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIEL

--------------------------------------------------------------
>In-frame_ENST00000366662_ENST00000539801_TCGA-E9-A22D-01A_TTC13_chr1_231090079_-_JAK2_chr9_5064883_length(transcript)=2908nt_BP=542nt
GGGCTGTCGCGCATGCGCCTTGAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGG
GCGCCGCCCGGCGTGTCCTGCTGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGC
CGCTCTCCCTGCTCAAGCAGGAGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACT
GGGGGGACCAGTACTCTGCCGAGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTG
ACTCCTTGCTTTCCCTCAACACTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATG
ACAGCACAAATGAAGAGTTAGCTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTC
AGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCGTGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCATT
ACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATATACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAGTA
AACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTCGATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGTCG
AGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAAAAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTTCA
GCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTGTTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCCAA
AGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATGGTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCATA
TGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGATATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAAAG
GCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAACAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTCAG
AGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTCACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGAGA
ATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATACATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACTTG
AAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAGAAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCTTA
TCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCAAACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACATTC
TTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAAATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTACCA
CTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTGCTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCAGC
TTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATAATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCATCA
TACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTATTAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGGGT
TTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAGAGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGGGA
GTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTGGGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCACC
TAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTACAGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGGTC
GGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAAGTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACATAA
AACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGTATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAATA
TATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTGGGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAAAG
AACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCACTGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGGAG
TGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAAGTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGGAC
AGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATGGAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGATCA
TGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCTTTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACATGGCTG

>In-frame_ENST00000366662_ENST00000539801_TCGA-E9-A22D-01A_TTC13_chr1_231090079_-_JAK2_chr9_5064883_length(amino acids)=951AA_start in transcript=29_stop in transcript=2884
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG
ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEIELSSLRE
ALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKH
CLITKNENEEYNLSGTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIR
NEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKF
GSLDTYLKKNKNCINILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPP
ECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTP
DYELLTENDMLPNMRIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEI
LKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVK
IGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIEL

--------------------------------------------------------------
>In-frame_ENST00000366662_ENST00000381652_TCGA-E9-A22D-01A_TTC13_chr1_231090079_-_JAK2_chr9_5064883_length(transcript)=4277nt_BP=542nt
GGGCTGTCGCGCATGCGCCTTGAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGG
GCGCCGCCCGGCGTGTCCTGCTGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGC
CGCTCTCCCTGCTCAAGCAGGAGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACT
GGGGGGACCAGTACTCTGCCGAGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTG
ACTCCTTGCTTTCCCTCAACACTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATG
ACAGCACAAATGAAGAGTTAGCTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTC
AGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCGTGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCATT
ACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATATACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAGTA
AACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTCGATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGTCG
AGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAAAAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTTCA
GCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTGTTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCCAA
AGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATGGTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCATA
TGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGATATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAAAG
GCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAACAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTCAG
AGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTCACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGAGA
ATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATACATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACTTG
AAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAGAAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCTTA
TCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCAAACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACATTC
TTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAAATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTACCA
CTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTGCTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCAGC
TTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATAATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCATCA
TACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTATTAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGGGT
TTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAGAGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGGGA
GTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTGGGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCACC
TAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTACAGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGGTC
GGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAAGTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACATAA
AACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGTATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAATA
TATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTGGGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAAAG
AACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCACTGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGGAG
TGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAAGTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGGAC
AGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATGGAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGATCA
TGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCTTTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACATGGCTG
GATGAAAGAAATGACCTTCATTCTGAGACCAAAGTAGATTTACAGAACAAAGTTTTATATTTCACATTGCTGTGGACTATTATTACATAT
ATCATTATTATATAAATCATGATGCTAGCCAGCAAAGATGTGAAAATATCTGCTCAAAACTTTCAAAGTTTAGTAAGTTTTTCTTCATGA
GGCCACCAGTAAAAGACATTAATGAGAATTCCTTAGCAAGGATTTTGTAAGAAGTTTCTTAAACATTGTCAGTTAACATCACTCTTGTCT
GGCAAAAGAAAAAAAATAGACTTTTTCAACTCAGCTTTTTGAGACCTGAAAAAATTATTATGTAAATTTTGCAATGTTAAAGATGCACAG
AATATGTATGTATAGTTTTTACCACAGTGGATGTATAATACCTTGGCATCTTGTGTGATGTTTTACACACATGAGGGCTGGTGTTCATTA
ATACTGTTTTCTAATTTTTCCATAGTTAATCTATAATTAATTACTTCACTATACAAACAAATTAAGATGTTCAGATAATTGAATAAGTAC
CTTTGTGTCCTTGTTCATTTATATCGCTGGCCAGCATTATAAGCAGGTGTATACTTTTAGCTTGTAGTTCCATGTACTGTAAATATTTTT
CACATAAAGGGAACAAATGTCTAGTTTTATTTGTATAGGAAATTTCCCTGACCCTAAATAATACATTTTGAAATGAAACAAGCTTACAAA
GATATAATCTATTTTATTATGGTTTCCCTTGTATCTATTTGTGGTGAATGTGTTTTTTAAATGGAACTATCTCCAAATTTTTCTAAGACT
ACTATGAACAGTTTTCTTTTAAAATTTTGAGATTAAGAATGCCAGGAATATTGTCATCCTTTGAGCTGCTGACTGCCAATAACATTCTTC
GATCTCTGGGATTTATGCTCATGAACTAAATTTAAGCTTAAGCCATAAAATAGATTAGATTGTTTTTTAAAAATGGATAGCTCATTAAGA
AGTGCAGCAGGTTAAGAATTTTTTCCTAAAGACTGTATATTTGAGGGGTTTCAGAATTTTGCATTGCAGTCATAGAAGAGATTTATTTCC
TTTTTAGAGGGGAAATGAGGTAAATAAGTAAAAAAGTATGCTTGTTAATTTTATTCAAGAATGCCAGTAGAAAATTCATAACGTGTATCT
TTAAGAAAAATGAGCATACATCTTAAATCTTTTCAATTAAGTATAAGGGGTTGTTCGTTGTTGTCATTTGTTATAGTGCTACTCCACTTT
AGACACCATAGCTAAAATAAAATATGGTGGGTTTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTATTTATACAAAACT

>In-frame_ENST00000366662_ENST00000381652_TCGA-E9-A22D-01A_TTC13_chr1_231090079_-_JAK2_chr9_5064883_length(amino acids)=951AA_start in transcript=29_stop in transcript=2884
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG
ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEIELSSLRE
ALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKH
CLITKNENEEYNLSGTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIR
NEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKF
GSLDTYLKKNKNCINILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPP
ECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTP
DYELLTENDMLPNMRIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEI
LKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVK
IGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIEL

--------------------------------------------------------------
>In-frame_ENST00000366662_ENST00000544510_TCGA-E9-A22D-01A_TTC13_chr1_231090079_-_JAK2_chr9_5064883_length(transcript)=2943nt_BP=542nt
GGGCTGTCGCGCATGCGCCTTGAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGCGG
GCGCCGCCCGGCGTGTCCTGCTGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTCGC
CGCTCTCCCTGCTCAAGCAGGAGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGACT
GGGGGGACCAGTACTCTGCCGAGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTGTG
ACTCCTTGCTTTCCCTCAACACTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAATG
ACAGCACAAATGAAGAGTTAGCTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCTTC
AGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCGTGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCATT
ACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATATACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAGTA
AACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTCGATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGTCG
AGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAAAAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTTCA
GCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTGTTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCCAA
AGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATGGTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCATA
TGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGATATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAAAG
GCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAACAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTCAG
AGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTCACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGAGA
ATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATACATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACTTG
AAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAGAAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCTTA
TCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCAAACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACATTC
TTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAAATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTACCA
CTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTGCTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCAGC
TTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATAATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCATCA
TACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTATTAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGGGT
TTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAGAGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGGGA
GTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTGGGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCACC
TAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTACAGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGGTC
GGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAAGTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACATAA
AACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGTATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAATA
TATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTGGGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAAAG
AACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCACTGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGGAG
TGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAAGTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGGAC
AGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATGGAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGATCA
TGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCTTTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACATGGCTG

>In-frame_ENST00000366662_ENST00000544510_TCGA-E9-A22D-01A_TTC13_chr1_231090079_-_JAK2_chr9_5064883_length(amino acids)=951AA_start in transcript=29_stop in transcript=2884
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG
ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEIELSSLRE
ALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKH
CLITKNENEEYNLSGTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIR
NEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKF
GSLDTYLKKNKNCINILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPP
ECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTP
DYELLTENDMLPNMRIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEI
LKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVK
IGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIEL

--------------------------------------------------------------
>In-frame_ENST00000414259_ENST00000539801_TCGA-E9-A22D-01A_TTC13_chr1_231090079_-_JAK2_chr9_5064883_length(transcript)=2910nt_BP=544nt
AAGGGCTGTCGCGCATGCGCCTTGAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGC
GGGCGCCGCCCGGCGTGTCCTGCTGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTC
GCCGCTCTCCCTGCTCAAGCAGGAGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGA
CTGGGGGGACCAGTACTCTGCCGAGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTG
TGACTCCTTGCTTTCCCTCAACACTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAA
TGACAGCACAAATGAAGAGTTAGCTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCT
TCAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCGTGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCA
TTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATATACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAG
TAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTCGATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGT
CGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAAAAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTT
CAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTGTTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCC
AAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATGGTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCA
TATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGATATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAA
AGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAACAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTC
AGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTCACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGA
GAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATACATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACT
TGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAGAAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCT
TATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCAAACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACAT
TCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAAATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTAC
CACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTGCTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCA
GCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATAATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCAT
CATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTATTAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGG
GTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAGAGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGG
GAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTGGGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCA
CCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTACAGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGG
TCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAAGTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACAT
AAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGTATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAA
TATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTGGGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAA
AGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCACTGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGG
AGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAAGTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGG
ACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATGGAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGAT
CATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCTTTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACATGGC

>In-frame_ENST00000414259_ENST00000539801_TCGA-E9-A22D-01A_TTC13_chr1_231090079_-_JAK2_chr9_5064883_length(amino acids)=951AA_start in transcript=31_stop in transcript=2886
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG
ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEIELSSLRE
ALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKH
CLITKNENEEYNLSGTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIR
NEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKF
GSLDTYLKKNKNCINILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPP
ECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTP
DYELLTENDMLPNMRIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEI
LKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVK
IGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIEL

--------------------------------------------------------------
>In-frame_ENST00000414259_ENST00000381652_TCGA-E9-A22D-01A_TTC13_chr1_231090079_-_JAK2_chr9_5064883_length(transcript)=4279nt_BP=544nt
AAGGGCTGTCGCGCATGCGCCTTGAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGC
GGGCGCCGCCCGGCGTGTCCTGCTGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTC
GCCGCTCTCCCTGCTCAAGCAGGAGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGA
CTGGGGGGACCAGTACTCTGCCGAGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTG
TGACTCCTTGCTTTCCCTCAACACTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAA
TGACAGCACAAATGAAGAGTTAGCTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCT
TCAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCGTGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCA
TTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATATACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAG
TAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTCGATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGT
CGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAAAAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTT
CAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTGTTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCC
AAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATGGTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCA
TATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGATATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAA
AGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAACAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTC
AGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTCACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGA
GAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATACATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACT
TGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAGAAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCT
TATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCAAACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACAT
TCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAAATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTAC
CACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTGCTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCA
GCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATAATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCAT
CATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTATTAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGG
GTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAGAGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGG
GAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTGGGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCA
CCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTACAGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGG
TCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAAGTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACAT
AAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGTATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAA
TATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTGGGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAA
AGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCACTGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGG
AGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAAGTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGG
ACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATGGAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGAT
CATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCTTTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACATGGC
TGGATGAAAGAAATGACCTTCATTCTGAGACCAAAGTAGATTTACAGAACAAAGTTTTATATTTCACATTGCTGTGGACTATTATTACAT
ATATCATTATTATATAAATCATGATGCTAGCCAGCAAAGATGTGAAAATATCTGCTCAAAACTTTCAAAGTTTAGTAAGTTTTTCTTCAT
GAGGCCACCAGTAAAAGACATTAATGAGAATTCCTTAGCAAGGATTTTGTAAGAAGTTTCTTAAACATTGTCAGTTAACATCACTCTTGT
CTGGCAAAAGAAAAAAAATAGACTTTTTCAACTCAGCTTTTTGAGACCTGAAAAAATTATTATGTAAATTTTGCAATGTTAAAGATGCAC
AGAATATGTATGTATAGTTTTTACCACAGTGGATGTATAATACCTTGGCATCTTGTGTGATGTTTTACACACATGAGGGCTGGTGTTCAT
TAATACTGTTTTCTAATTTTTCCATAGTTAATCTATAATTAATTACTTCACTATACAAACAAATTAAGATGTTCAGATAATTGAATAAGT
ACCTTTGTGTCCTTGTTCATTTATATCGCTGGCCAGCATTATAAGCAGGTGTATACTTTTAGCTTGTAGTTCCATGTACTGTAAATATTT
TTCACATAAAGGGAACAAATGTCTAGTTTTATTTGTATAGGAAATTTCCCTGACCCTAAATAATACATTTTGAAATGAAACAAGCTTACA
AAGATATAATCTATTTTATTATGGTTTCCCTTGTATCTATTTGTGGTGAATGTGTTTTTTAAATGGAACTATCTCCAAATTTTTCTAAGA
CTACTATGAACAGTTTTCTTTTAAAATTTTGAGATTAAGAATGCCAGGAATATTGTCATCCTTTGAGCTGCTGACTGCCAATAACATTCT
TCGATCTCTGGGATTTATGCTCATGAACTAAATTTAAGCTTAAGCCATAAAATAGATTAGATTGTTTTTTAAAAATGGATAGCTCATTAA
GAAGTGCAGCAGGTTAAGAATTTTTTCCTAAAGACTGTATATTTGAGGGGTTTCAGAATTTTGCATTGCAGTCATAGAAGAGATTTATTT
CCTTTTTAGAGGGGAAATGAGGTAAATAAGTAAAAAAGTATGCTTGTTAATTTTATTCAAGAATGCCAGTAGAAAATTCATAACGTGTAT
CTTTAAGAAAAATGAGCATACATCTTAAATCTTTTCAATTAAGTATAAGGGGTTGTTCGTTGTTGTCATTTGTTATAGTGCTACTCCACT
TTAGACACCATAGCTAAAATAAAATATGGTGGGTTTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTATTTATACAAAA

>In-frame_ENST00000414259_ENST00000381652_TCGA-E9-A22D-01A_TTC13_chr1_231090079_-_JAK2_chr9_5064883_length(amino acids)=951AA_start in transcript=31_stop in transcript=2886
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG
ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEIELSSLRE
ALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKH
CLITKNENEEYNLSGTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIR
NEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKF
GSLDTYLKKNKNCINILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPP
ECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTP
DYELLTENDMLPNMRIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEI
LKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVK
IGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIEL

--------------------------------------------------------------
>In-frame_ENST00000414259_ENST00000544510_TCGA-E9-A22D-01A_TTC13_chr1_231090079_-_JAK2_chr9_5064883_length(transcript)=2945nt_BP=544nt
AAGGGCTGTCGCGCATGCGCCTTGAGGGAAGATGGCACCTGCCGGCTGCTGCTGCTGCTGCTGCTTCTGGGGCGGCGCTGTGGCCGCCGC
GGGCGCCGCCCGGCGTGTCCTGCTGCTGCTGCTGCTGGGGGTCCTGTCCGCCGGGCTGCGGCCAGGCGCCCTGGCCACCGAGCACTACTC
GCCGCTCTCCCTGCTCAAGCAGGAGCTGCAGCACCGGCAGCAGCAGGAGGCCCCGGCGGGCGGCGGCGGCTGCAGCCCGCAGTCCGGGGA
CTGGGGGGACCAGTACTCTGCCGAGTGCGGCGAGTCATCCTTTTTGAACTTCCATGACTCAGACTGCGAACCCAAGGGATCATCACCCTG
TGACTCCTTGCTTTCCCTCAACACTGAGAAGATTCTGAGCCAGGCCAAGTCTATTGCAGAACAGAAGAGATTCCCGTTTGCCACTGATAA
TGACAGCACAAATGAAGAGTTAGCTATTGCTTATGTCTTGATTGGCAGTGGTCTGTATGATGAAGCAATACGGCATTTTTCAACAATGCT
TCAGGAAATTGAACTTAGCTCATTAAGGGAAGCTTTGTCTTTCGTGTCATTAATTGATGGATATTATAGATTAACTGCAGATGCACATCA
TTACCTCTGTAAAGAAGTAGCACCTCCAGCCGTGCTTGAAAATATACAAAGCAACTGTCATGGCCCAATTTCGATGGATTTTGCCATTAG
TAAACTGAAGAAAGCAGGTAATCAGACTGGACTGTATGTACTTCGATGCAGTCCTAAGGACTTTAATAAATATTTTTTGACTTTTGCTGT
CGAGCGAGAAAATGTCATTGAATATAAACACTGTTTGATTACAAAAAATGAGAATGAAGAGTACAACCTCAGTGGGACAAAGAAGAACTT
CAGCAGTCTTAAAGATCTTTTGAATTGTTACCAGATGGAAACTGTTCGCTCAGACAATATAATTTTCCAGTTTACTAAATGCTGTCCCCC
AAAGCCAAAAGATAAATCAAACCTTCTAGTCTTCAGAACGAATGGTGTTTCTGATGTACCAACCTCACCAACATTACAGAGGCCTACTCA
TATGAACCAAATGGTGTTTCACAAAATCAGAAATGAAGATTTGATATTTAATGAAAGCCTTGGCCAAGGCACTTTTACAAAGATTTTTAA
AGGCGTACGAAGAGAAGTAGGAGACTACGGTCAACTGCATGAAACAGAAGTTCTTTTAAAAGTTCTGGATAAAGCACACAGAAACTATTC
AGAGTCTTTCTTTGAAGCAGCAAGTATGATGAGCAAGCTTTCTCACAAGCATTTGGTTTTAAATTATGGAGTATGTGTCTGTGGAGACGA
GAATATTCTGGTTCAGGAGTTTGTAAAATTTGGATCACTAGATACATATCTGAAAAAGAATAAAAATTGTATAAATATATTATGGAAACT
TGAAGTTGCTAAACAGTTGGCATGGGCCATGCATTTTCTAGAAGAAAACACCCTTATTCATGGGAATGTATGTGCCAAAAATATTCTGCT
TATCAGAGAAGAAGACAGGAAGACAGGAAATCCTCCTTTCATCAAACTTAGTGATCCTGGCATTAGTATTACAGTTTTGCCAAAGGACAT
TCTTCAGGAGAGAATACCATGGGTACCACCTGAATGCATTGAAAATCCTAAAAATTTAAATTTGGCAACAGACAAATGGAGTTTTGGTAC
CACTTTGTGGGAAATCTGCAGTGGAGGAGATAAACCTCTAAGTGCTCTGGATTCTCAAAGAAAGCTACAATTTTATGAAGATAGGCATCA
GCTTCCTGCACCAAAGTGGGCAGAATTAGCAAACCTTATAAATAATTGTATGGATTATGAACCAGATTTCAGGCCTTCTTTCAGAGCCAT
CATACGAGATCTTAACAGTTTGTTTACTCCAGATTATGAACTATTAACAGAAAATGACATGTTACCAAATATGAGGATAGGTGCCCTGGG
GTTTTCTGGTGCCTTTGAAGACCGGGATCCTACACAGTTTGAAGAGAGACATTTGAAATTTCTACAGCAACTTGGCAAGGGTAATTTTGG
GAGTGTGGAGATGTGCCGGTATGACCCTCTACAGGACAACACTGGGGAGGTGGTCGCTGTAAAAAAGCTTCAGCATAGTACTGAAGAGCA
CCTAAGAGACTTTGAAAGGGAAATTGAAATCCTGAAATCCCTACAGCATGACAACATTGTAAAGTACAAGGGAGTGTGCTACAGTGCTGG
TCGGCGTAATCTAAAATTAATTATGGAATATTTACCATATGGAAGTTTACGAGACTATCTTCAAAAACATAAAGAACGGATAGATCACAT
AAAACTTCTGCAGTACACATCTCAGATATGCAAGGGTATGGAGTATCTTGGTACAAAAAGGTATATCCACAGGGATCTGGCAACGAGAAA
TATATTGGTGGAGAACGAGAACAGAGTTAAAATTGGAGATTTTGGGTTAACCAAAGTCTTGCCACAAGACAAAGAATACTATAAAGTAAA
AGAACCTGGTGAAAGTCCCATATTCTGGTATGCTCCAGAATCACTGACAGAGAGCAAGTTTTCTGTGGCCTCAGATGTTTGGAGCTTTGG
AGTGGTTCTGTATGAACTTTTCACATACATTGAGAAGAGTAAAAGTCCACCAGCGGAATTTATGCGTATGATTGGCAATGACAAACAAGG
ACAGATGATCGTGTTCCATTTGATAGAACTTTTGAAGAATAATGGAAGATTACCAAGACCAGATGGATGCCCAGATGAGATCTATATGAT
CATGACAGAATGCTGGAACAATAATGTAAATCAACGCCCCTCCTTTAGGGATCTAGCTCTTCGAGTGGATCAAATAAGGGATAACATGGC

>In-frame_ENST00000414259_ENST00000544510_TCGA-E9-A22D-01A_TTC13_chr1_231090079_-_JAK2_chr9_5064883_length(amino acids)=951AA_start in transcript=31_stop in transcript=2886
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECG
ESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEIELSSLRE
ALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKH
CLITKNENEEYNLSGTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIR
NEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKF
GSLDTYLKKNKNCINILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPP
ECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTP
DYELLTENDMLPNMRIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEI
LKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVK
IGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIEL

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for TTC13-JAK2

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Interaction lost with
Tgene	JAK2	chr1:231075131	chr9:5064882	ENST00000381652		7	25	1_239	352.0	1133.0	cytokine/interferon/growth hormone receptors
Tgene	JAK2	chr1:231075131	chr9:5064882	ENST00000539801		6	24	1_239	352.0	1133.0	cytokine/interferon/growth hormone receptors
Tgene	JAK2	chr1:231075132	chr9:5064883	ENST00000381652		7	25	1_239	352.0	1133.0	cytokine/interferon/growth hormone receptors
Tgene	JAK2	chr1:231075132	chr9:5064883	ENST00000539801		6	24	1_239	352.0	1133.0	cytokine/interferon/growth hormone receptors
Tgene	JAK2	chr1:231079552	chr9:5064883	ENST00000381652		7	25	1_239	352.0	1133.0	cytokine/interferon/growth hormone receptors
Tgene	JAK2	chr1:231079552	chr9:5064883	ENST00000539801		6	24	1_239	352.0	1133.0	cytokine/interferon/growth hormone receptors
Tgene	JAK2	chr1:231090079	chr9:5064883	ENST00000381652		7	25	1_239	352.0	1133.0	cytokine/interferon/growth hormone receptors
Tgene	JAK2	chr1:231090079	chr9:5064883	ENST00000539801		6	24	1_239	352.0	1133.0	cytokine/interferon/growth hormone receptors

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for TTC13-JAK2

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner	Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
Tgene	JAK2	O60674	DB08877	Ruxolitinib	Inhibitor	Small molecule	Approved
Tgene	JAK2	O60674	DB08895	Tofacitinib	Antagonist\|Inhibitor	Small molecule	Approved\|Investigational
Tgene	JAK2	O60674	DB11817	Baricitinib	Inhibitor	Small molecule	Approved\|Investigational
Tgene	JAK2	O60674	DB11986	Entrectinib	Inhibitor	Small molecule	Approved\|Investigational
Tgene	JAK2	O60674	DB12010	Fostamatinib	Inhibitor	Small molecule	Approved\|Investigational
Tgene	JAK2	O60674	DB12500	Fedratinib	Inhibitor	Small molecule	Approved\|Investigational
Tgene	JAK2	O60674	DB15035	Zanubrutinib	Inhibitor	Small molecule	Approved\|Investigational
Tgene	JAK2	O60674	DB15822	Pralsetinib	Inhibitor	Small molecule	Approved\|Investigational

Top

Related Diseases for TTC13-JAK2

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Tgene	JAK2	C0032463	Polycythemia Vera	12	CTD_human;ORPHANET;UNIPROT
Tgene	JAK2	C0040028	Thrombocythemia, Essential	10	CTD_human;ORPHANET
Tgene	JAK2	C0001815	Primary Myelofibrosis	9	CGI;CTD_human;GENOMICS_ENGLAND;ORPHANET
Tgene	JAK2	C3489628	Thrombocytosis, Autosomal Dominant	8	CTD_human
Tgene	JAK2	C0019154	Hepatic Vein Thrombosis	3	CTD_human;ORPHANET
Tgene	JAK2	C0856761	Budd-Chiari Syndrome	3	CTD_human;ORPHANET
Tgene	JAK2	C0009324	Ulcerative Colitis	2	CTD_human
Tgene	JAK2	C0027022	Myeloproliferative disease	2	CTD_human
Tgene	JAK2	C0151744	Myocardial Ischemia	2	CTD_human
Tgene	JAK2	C0836924	Thrombocytosis	2	CTD_human
Tgene	JAK2	C3281125	THROMBOCYTHEMIA 3	2	UNIPROT
Tgene	JAK2	C0000786	Spontaneous abortion	1	CTD_human
Tgene	JAK2	C0000822	Abortion, Tubal	1	CTD_human
Tgene	JAK2	C0006663	Calcinosis	1	CTD_human
Tgene	JAK2	C0007873	Uterine Cervical Neoplasm	1	CTD_human
Tgene	JAK2	C0018824	Heart valve disease	1	CTD_human
Tgene	JAK2	C0019207	Hepatoma, Morris	1	CTD_human
Tgene	JAK2	C0019208	Hepatoma, Novikoff	1	CTD_human
Tgene	JAK2	C0021368	Inflammation	1	CTD_human
Tgene	JAK2	C0023418	leukemia	1	CTD_human
Tgene	JAK2	C0023467	Leukemia, Myelocytic, Acute	1	CGI;CTD_human;UNIPROT
Tgene	JAK2	C0023893	Liver Cirrhosis, Experimental	1	CTD_human
Tgene	JAK2	C0023904	Liver Neoplasms, Experimental	1	CTD_human
Tgene	JAK2	C0025472	Mesenteric Vascular Occlusion	1	CTD_human
Tgene	JAK2	C0026998	Acute Myeloid Leukemia, M1	1	CTD_human
Tgene	JAK2	C0032461	Polycythemia	1	CTD_human
Tgene	JAK2	C0032962	Pregnancy Complications	1	CTD_human
Tgene	JAK2	C0033578	Prostatic Neoplasms	1	CTD_human
Tgene	JAK2	C0040038	Thromboembolism	1	CTD_human
Tgene	JAK2	C0042487	Venous Thrombosis	1	CTD_human
Tgene	JAK2	C0086404	Experimental Hepatoma	1	CTD_human
Tgene	JAK2	C0149871	Deep Vein Thrombosis	1	CTD_human
Tgene	JAK2	C0263628	Tumoral calcinosis	1	CTD_human
Tgene	JAK2	C0376358	Malignant neoplasm of prostate	1	CTD_human
Tgene	JAK2	C0400966	Non-alcoholic Fatty Liver Disease	1	CTD_human
Tgene	JAK2	C0521174	Microcalcification	1	CTD_human
Tgene	JAK2	C1527405	Erythrocytosis	1	CTD_human
Tgene	JAK2	C1879321	Acute Myeloid Leukemia (AML-M2)	1	CTD_human
Tgene	JAK2	C3241937	Nonalcoholic Steatohepatitis	1	CTD_human
Tgene	JAK2	C3495676	Anorectal Malformations	1	GENOMICS_ENGLAND
Tgene	JAK2	C3830362	Early Pregnancy Loss	1	CTD_human
Tgene	JAK2	C4048328	cervical cancer	1	CTD_human
Tgene	JAK2	C4303761	Familial thrombocytosis	1	ORPHANET
Tgene	JAK2	C4552766	Miscarriage	1	CTD_human