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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TTK-TMEM63B (FusionGDB2 ID:94477)

Fusion Gene Summary for TTK-TMEM63B

check button Fusion gene summary
Fusion gene informationFusion gene name: TTK-TMEM63B
Fusion gene ID: 94477
HgeneTgene
Gene symbol

TTK

TMEM63B

Gene ID

7272

55362

Gene nameTTK protein kinasetransmembrane protein 63B
SynonymsCT96|ESK|MPH1|MPS1|MPS1L1|PYTC6orf110
Cytomap

6q14.1

6p21.1

Type of geneprotein-codingprotein-coding
Descriptiondual specificity protein kinase TTKcancer/testis antigen 96monopolar spindle 1 kinasemonopolar spindle 1-like 1phosphotyrosine picked threonine kinasephosphotyrosine picked threonine-protein kinaseCSC1-like protein 2
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000509894, ENST00000230510, 
ENST00000369798, ENST00000515751, 
ENST00000259746, ENST00000323267, 
ENST00000527188, 
Fusion gene scores* DoF score2 X 2 X 2=83 X 5 X 3=45
# samples 35
** MAII scorelog2(3/8*10)=1.90689059560852log2(5/45*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: TTK [Title/Abstract] AND TMEM63B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTTK(80721265)-TMEM63B(44119583), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across TTK (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across TMEM63B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-DX-A23Y-01ATTKchr6

80721265

+TMEM63Bchr6

44119583

+
ChimerDB4SARCTCGA-DX-A23YTTKchr6

80721265

+TMEM63Bchr6

44119582

+
ChimerDB4SARCTCGA-DX-A23Y-01ATTKchr6

80721265

-TMEM63Bchr6

44119583

+


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Fusion Gene ORF analysis for TTK-TMEM63B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000509894ENST00000259746TTKchr6

80721265

+TMEM63Bchr6

44119583

+
In-frameENST00000509894ENST00000323267TTKchr6

80721265

+TMEM63Bchr6

44119583

+
5CDS-intronENST00000509894ENST00000527188TTKchr6

80721265

+TMEM63Bchr6

44119583

+
In-frameENST00000230510ENST00000259746TTKchr6

80721265

+TMEM63Bchr6

44119583

+
In-frameENST00000230510ENST00000323267TTKchr6

80721265

+TMEM63Bchr6

44119583

+
5CDS-intronENST00000230510ENST00000527188TTKchr6

80721265

+TMEM63Bchr6

44119583

+
In-frameENST00000369798ENST00000259746TTKchr6

80721265

+TMEM63Bchr6

44119583

+
In-frameENST00000369798ENST00000323267TTKchr6

80721265

+TMEM63Bchr6

44119583

+
5CDS-intronENST00000369798ENST00000527188TTKchr6

80721265

+TMEM63Bchr6

44119583

+
intron-3CDSENST00000515751ENST00000259746TTKchr6

80721265

+TMEM63Bchr6

44119583

+
intron-3CDSENST00000515751ENST00000323267TTKchr6

80721265

+TMEM63Bchr6

44119583

+
intron-intronENST00000515751ENST00000527188TTKchr6

80721265

+TMEM63Bchr6

44119583

+
In-frameENST00000509894ENST00000259746TTKchr6

80721265

+TMEM63Bchr6

44119582

+
In-frameENST00000509894ENST00000323267TTKchr6

80721265

+TMEM63Bchr6

44119582

+
5CDS-intronENST00000509894ENST00000527188TTKchr6

80721265

+TMEM63Bchr6

44119582

+
In-frameENST00000230510ENST00000259746TTKchr6

80721265

+TMEM63Bchr6

44119582

+
In-frameENST00000230510ENST00000323267TTKchr6

80721265

+TMEM63Bchr6

44119582

+
5CDS-intronENST00000230510ENST00000527188TTKchr6

80721265

+TMEM63Bchr6

44119582

+
In-frameENST00000369798ENST00000259746TTKchr6

80721265

+TMEM63Bchr6

44119582

+
In-frameENST00000369798ENST00000323267TTKchr6

80721265

+TMEM63Bchr6

44119582

+
5CDS-intronENST00000369798ENST00000527188TTKchr6

80721265

+TMEM63Bchr6

44119582

+
intron-3CDSENST00000515751ENST00000259746TTKchr6

80721265

+TMEM63Bchr6

44119582

+
intron-3CDSENST00000515751ENST00000323267TTKchr6

80721265

+TMEM63Bchr6

44119582

+
intron-intronENST00000515751ENST00000527188TTKchr6

80721265

+TMEM63Bchr6

44119582

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000509894TTKchr680721265+ENST00000259746TMEM63Bchr644119583+301915578292382517
ENST00000509894TTKchr680721265+ENST00000323267TMEM63Bchr644119583+301815578292382517
ENST00000230510TTKchr680721265+ENST00000259746TMEM63Bchr644119583+277113095812134517
ENST00000230510TTKchr680721265+ENST00000323267TMEM63Bchr644119583+277013095812134517
ENST00000369798TTKchr680721265+ENST00000259746TMEM63Bchr644119583+23018391111664517
ENST00000369798TTKchr680721265+ENST00000323267TMEM63Bchr644119583+23008391111664517
ENST00000509894TTKchr680721265+ENST00000259746TMEM63Bchr644119582+301915578292382517
ENST00000509894TTKchr680721265+ENST00000323267TMEM63Bchr644119582+301815578292382517
ENST00000230510TTKchr680721265+ENST00000259746TMEM63Bchr644119582+277113095812134517
ENST00000230510TTKchr680721265+ENST00000323267TMEM63Bchr644119582+277013095812134517
ENST00000369798TTKchr680721265+ENST00000259746TMEM63Bchr644119582+23018391111664517
ENST00000369798TTKchr680721265+ENST00000323267TMEM63Bchr644119582+23008391111664517

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000509894ENST00000259746TTKchr680721265+TMEM63Bchr644119583+0.0012814030.9987186
ENST00000509894ENST00000323267TTKchr680721265+TMEM63Bchr644119583+0.0012681830.9987318
ENST00000230510ENST00000259746TTKchr680721265+TMEM63Bchr644119583+0.0013166890.9986833
ENST00000230510ENST00000323267TTKchr680721265+TMEM63Bchr644119583+0.0013054430.9986946
ENST00000369798ENST00000259746TTKchr680721265+TMEM63Bchr644119583+0.0009392720.9990607
ENST00000369798ENST00000323267TTKchr680721265+TMEM63Bchr644119583+0.0009308940.99906915
ENST00000509894ENST00000259746TTKchr680721265+TMEM63Bchr644119582+0.0012814030.9987186
ENST00000509894ENST00000323267TTKchr680721265+TMEM63Bchr644119582+0.0012681830.9987318
ENST00000230510ENST00000259746TTKchr680721265+TMEM63Bchr644119582+0.0013166890.9986833
ENST00000230510ENST00000323267TTKchr680721265+TMEM63Bchr644119582+0.0013054430.9986946
ENST00000369798ENST00000259746TTKchr680721265+TMEM63Bchr644119582+0.0009392720.9990607
ENST00000369798ENST00000323267TTKchr680721265+TMEM63Bchr644119582+0.0009308940.99906915

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Fusion Genomic Features for TTK-TMEM63B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
TTKchr680721265+TMEM63Bchr644119582+1.07E-050.9999893
TTKchr680721265+TMEM63Bchr644119582+1.07E-050.9999893
TTKchr680721265+TMEM63Bchr644119582+1.07E-050.9999893
TTKchr680721265+TMEM63Bchr644119582+1.07E-050.9999893

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for TTK-TMEM63B


check button Go to

FGviewer for the breakpoints of chr6:80721265-chr6:44119583

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTMEM63Bchr6:80721265chr6:44119582ENST000002597461724560_580557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119582ENST000002597461724630_650557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119582ENST000002597461724678_698557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119582ENST000002597461724711_731557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119582ENST000003232671724560_580557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119582ENST000003232671724630_650557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119582ENST000003232671724678_698557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119582ENST000003232671724711_731557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119583ENST000002597461724560_580557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119583ENST000002597461724630_650557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119583ENST000002597461724678_698557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119583ENST000002597461724711_731557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119583ENST000003232671724560_580557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119583ENST000003232671724630_650557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119583ENST000003232671724678_698557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119583ENST000003232671724711_731557.6666666666666833.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTTKchr6:80721265chr6:44119582ENST00000230510+622525_791242.66666666666666857.0DomainProtein kinase
HgeneTTKchr6:80721265chr6:44119582ENST00000369798+622525_791242.66666666666666858.0DomainProtein kinase
HgeneTTKchr6:80721265chr6:44119582ENST00000509894+622525_791242.66666666666666857.0DomainProtein kinase
HgeneTTKchr6:80721265chr6:44119583ENST00000230510+622525_791242.66666666666666857.0DomainProtein kinase
HgeneTTKchr6:80721265chr6:44119583ENST00000369798+622525_791242.66666666666666858.0DomainProtein kinase
HgeneTTKchr6:80721265chr6:44119583ENST00000509894+622525_791242.66666666666666857.0DomainProtein kinase
HgeneTTKchr6:80721265chr6:44119582ENST00000230510+622531_539242.66666666666666857.0Nucleotide bindingATP
HgeneTTKchr6:80721265chr6:44119582ENST00000369798+622531_539242.66666666666666858.0Nucleotide bindingATP
HgeneTTKchr6:80721265chr6:44119582ENST00000509894+622531_539242.66666666666666857.0Nucleotide bindingATP
HgeneTTKchr6:80721265chr6:44119583ENST00000230510+622531_539242.66666666666666857.0Nucleotide bindingATP
HgeneTTKchr6:80721265chr6:44119583ENST00000369798+622531_539242.66666666666666858.0Nucleotide bindingATP
HgeneTTKchr6:80721265chr6:44119583ENST00000509894+622531_539242.66666666666666857.0Nucleotide bindingATP
TgeneTMEM63Bchr6:80721265chr6:44119582ENST000002597461724158_178557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119582ENST000002597461724203_223557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119582ENST00000259746172441_61557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119582ENST000002597461724435_455557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119582ENST000002597461724481_501557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119582ENST000002597461724521_541557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119582ENST000003232671724158_178557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119582ENST000003232671724203_223557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119582ENST00000323267172441_61557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119582ENST000003232671724435_455557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119582ENST000003232671724481_501557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119582ENST000003232671724521_541557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119583ENST000002597461724158_178557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119583ENST000002597461724203_223557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119583ENST00000259746172441_61557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119583ENST000002597461724435_455557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119583ENST000002597461724481_501557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119583ENST000002597461724521_541557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119583ENST000003232671724158_178557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119583ENST000003232671724203_223557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119583ENST00000323267172441_61557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119583ENST000003232671724435_455557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119583ENST000003232671724481_501557.6666666666666833.0TransmembraneHelical
TgeneTMEM63Bchr6:80721265chr6:44119583ENST000003232671724521_541557.6666666666666833.0TransmembraneHelical


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Fusion Gene Sequence for TTK-TMEM63B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000509894_ENST00000259746_TCGA-DX-A23Y-01A_TTK_chr6_80721265_+_TMEM63B_chr6_44119583_length(transcript)=3019nt_BP=1557nt
ACCACAAAGCCACTTAGCGGCAGAGCCTCGCACCCGCGAAGATTATTACTAGGGAGATGTTTTTACCCCTGAGGACACCTGAGCCCTTAA
GTGGGGCAGGCTTCGAGGGAGGGGGGCCGATAAGGCGACTTCAGACAGGGCAATCACGATGGGCGCTTGAGTTCTGCGCAGAATTTTGAC
AAGGGGGAGGGTCTTGGCTTGAAGACAGAGCGTGGAGTCATTTAAGGATAATGGAAGGGCATAAGCAGAAGCTCAAGGATAAAAAGCACT
GAAATTCTTGAGCTGGCGGCAGGGCTGAACGTAGCTCAGTGAAAGATCCTTTCTTGCCACATCCTCTCTAAGCCAGGCTGTGAGAACCGC
GGGAAACGAAGGAGAAGGGTGGCGGTGGGGTCAGTAAAGGGCCGGCCCAAGGTGCATCTTTTAGGTCCTGATGCTAGGAGCAGCCGTCCC
TGCCCCTATATTCCTCTCACTGGGTAGGTTTGCTCGGGAGTGGCTACCTCCCAGGCAAAAATTCGGCCTGGTTAAACTGGAAAGACCAGG
AAAGCCCGCCCACGGGCGTCCGGGGAACGCCTGCAAAGTGCCAGCACCCTACCAACCCAGGCGCCGCACGGGTGGGGTCGCGGCCGCAGG
CTCTTCCGGGGCGGGCCTAGCCTGACGCAGGAGGAGGGGCGGCCCCCGTCGCACAAGAACCAATCACGACTGTCGCTTCTACGTGGCTAG
CATTGACCAATAGGAGACCGTAGTGATAGCGACGGGGAAATTCAAACGTGTTTGCGGAAAGGAGTTTGGGTTCCATCTTTTCATTTCCCC
AGCGCAGCTTTCTGTAGAAATGGAATCCGAGGATTTAAGTGGCAGAGAATTGACAATTGATTCCATAATGAACAAAGTGAGAGACATTAA
AAATAAGTTTAAAAATGAAGACCTTACTGATGAACTAAGCTTGAATAAAATTTCTGCTGATACTACAGATAACTCGGGAACTGTTAACCA
AATTATGATGATGGCAAACAACCCAGAGGACTGGTTGAGTTTGTTGCTCAAACTAGAGAAAAACAGTGTTCCGCTAAGTGATGCTCTTTT
AAATAAATTGATTGGTCGTTACAGTCAAGCAATTGAAGCGCTTCCCCCAGATAAATATGGCCAAAATGAGAGTTTTGCTAGAATTCAAGT
GAGATTTGCTGAATTAAAAGCTATTCAAGAGCCAGATGATGCACGTGACTACTTTCAAATGGCCAGAGCAAACTGCAAGAAATTTGCTTT
TGTTCATATATCTTTTGCACAATTTGAACTGTCACAAGGTAATGTCAAAAAAAGTAAACAACTTCTTCAAAAAGCTGTAGAACGTGGAGC
AGTACCACTAGAAATGCTGGAAATTGCCCTGCGGAATTTAAACCTCCAAAAAAAGCAGCTGCTTTCAGAGGAGGAAAAGAAGAATTTATC
AGCATCTACGGTATTAACTGCCCAAGAATCATTTTCCGGTTCACTTGGGCATTTACAGAATAGGAACAACAGTTGTGATTCCAGAGGACA
GACTACTAAAGCCAGGTTTTTATATGGGTGTGTGTTCCTGCCCGACAACGGCGCCTTCTTCGTGAACTACGTCATTGCCTCAGCCTTTAT
CGGCAACGCCATGGACCTGCTGCGCATCCCAGGCCTGCTCATGTACATGATCCGGCTCTGCCTGGCGCGCTCGGCCGCCGAGAGGCGCAA
CGTGAAGCGGCATCAGGCCTACGAGTTCCAGTTTGGCGCAGCCTACGCCTGGATGATGTGCGTCTTCACGGTGGTCATGACCTACAGTAT
CACCTGCCCCATCATCGTGCCCTTCGGGCTCATGTACATGCTGCTGAAGCACCTGGTAGACAGGTACAATCTCTACTACGCCTACCTGCC
GGCCAAGCTGGACAAGAAGATCCACTCGGGGGCTGTGAACCAGGTGGTGGCCGCGCCCATCCTCTGCCTCTTCTGGCTGCTCTTCTTTTC
CACCATGCGCACGGGGTTCCTAGCTCCCACGTCTATGTTCACATTTGTGGTCCTGGTCATCACCATCGTCATCTGTCTCTGCCACGTCTG
CTTTGGACACTTCAAATACCTCAGTGCCCACAACTACAAGATTGAGCACACGGAGACAGATACTGTGGACCCCAGAAGCAATGGACGGCC
CCCCACTGCTGCTGCTGTCCCCAAATCTGCGAAATACATCGCTCAGGTGCTGCAGGACTCAGAGGTGGACGGGGATGGGGATGGGGCTCC
TGGGAGCTCAGGGGATGAGCCCCCATCATCCTCATCCCAAGATGAGGAGTTGCTGATGCCACCCGACGCCCTCACGGACACAGACTTCCA
GTCTTGCGAGGACAGCCTCATAGAGAATGAGATTCACCAGTAAGGGGAGGGAGGGGCCCTGGAGGCCACATCCTGCCCCACCCCACCCCC
ACTCCCACGGACACTAAAACGCTAATAATTTATTAGATCTAAAGCCCCTTCCTCCCCAGCCCCTGCTTTCATTAAGGTATTTAAACTTGG
GGGTTTCACTGCTCTCCCCCATGATGGAGGGAGGGAGCCCCCCAACCTCAGTGAGGAGAGCCCCGAGCCGGCCCCGGGGCAAAGAGGGGT
GCAGAGGGAGTTCCCCCAGATCAGTACCCCCCACCCCTCCCCAGCTAGTAGCATGACCAGGAGAGGGTTAATGAGAGCCAAGAGGAGTAC
CTGGTGCACCTGGTGCCGGTGGCTGGAGACCTGGGGGGCAGGTGGATCTGGGGCTGTTCCCCCCCCTCCGTTTTTTCCACCCCACAGTTC
CTCCTGGGATCTGGCCCTCCAGGGAAGTGGAGCCTCCAGCCCCTAGGGGATGCATGAGGGGGGAGGGGGTGCTGAGTGGGAGGAAGAGTC
AGGCTCACAGCTGGGGTGGCCTGGGGGTGGGGGTGGGCAAGGCTGACACTGGAAAATGGGTTTTTGCACTGTTTTTTTTTTGGTTTTTTT

>In-frame_ENST00000509894_ENST00000259746_TCGA-DX-A23Y-01A_TTK_chr6_80721265_+_TMEM63B_chr6_44119583_length(amino acids)=517AA_start in transcript=829_stop in transcript=2382
MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMANNPEDWLSLLLKLEKNSVPLSDALLNKLIGR
YSQAIEALPPDKYGQNESFARIQVRFAELKAIQEPDDARDYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEML
EIALRNLNLQKKQLLSEEEKKNLSASTVLTAQESFSGSLGHLQNRNNSCDSRGQTTKARFLYGCVFLPDNGAFFVNYVIASAFIGNAMDL
LRIPGLLMYMIRLCLARSAAERRNVKRHQAYEFQFGAAYAWMMCVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNLYYAYLPAKLDKK
IHSGAVNQVVAAPILCLFWLLFFSTMRTGFLAPTSMFTFVVLVITIVICLCHVCFGHFKYLSAHNYKIEHTETDTVDPRSNGRPPTAAAV

--------------------------------------------------------------
>In-frame_ENST00000509894_ENST00000323267_TCGA-DX-A23Y-01A_TTK_chr6_80721265_+_TMEM63B_chr6_44119583_length(transcript)=3018nt_BP=1557nt
ACCACAAAGCCACTTAGCGGCAGAGCCTCGCACCCGCGAAGATTATTACTAGGGAGATGTTTTTACCCCTGAGGACACCTGAGCCCTTAA
GTGGGGCAGGCTTCGAGGGAGGGGGGCCGATAAGGCGACTTCAGACAGGGCAATCACGATGGGCGCTTGAGTTCTGCGCAGAATTTTGAC
AAGGGGGAGGGTCTTGGCTTGAAGACAGAGCGTGGAGTCATTTAAGGATAATGGAAGGGCATAAGCAGAAGCTCAAGGATAAAAAGCACT
GAAATTCTTGAGCTGGCGGCAGGGCTGAACGTAGCTCAGTGAAAGATCCTTTCTTGCCACATCCTCTCTAAGCCAGGCTGTGAGAACCGC
GGGAAACGAAGGAGAAGGGTGGCGGTGGGGTCAGTAAAGGGCCGGCCCAAGGTGCATCTTTTAGGTCCTGATGCTAGGAGCAGCCGTCCC
TGCCCCTATATTCCTCTCACTGGGTAGGTTTGCTCGGGAGTGGCTACCTCCCAGGCAAAAATTCGGCCTGGTTAAACTGGAAAGACCAGG
AAAGCCCGCCCACGGGCGTCCGGGGAACGCCTGCAAAGTGCCAGCACCCTACCAACCCAGGCGCCGCACGGGTGGGGTCGCGGCCGCAGG
CTCTTCCGGGGCGGGCCTAGCCTGACGCAGGAGGAGGGGCGGCCCCCGTCGCACAAGAACCAATCACGACTGTCGCTTCTACGTGGCTAG
CATTGACCAATAGGAGACCGTAGTGATAGCGACGGGGAAATTCAAACGTGTTTGCGGAAAGGAGTTTGGGTTCCATCTTTTCATTTCCCC
AGCGCAGCTTTCTGTAGAAATGGAATCCGAGGATTTAAGTGGCAGAGAATTGACAATTGATTCCATAATGAACAAAGTGAGAGACATTAA
AAATAAGTTTAAAAATGAAGACCTTACTGATGAACTAAGCTTGAATAAAATTTCTGCTGATACTACAGATAACTCGGGAACTGTTAACCA
AATTATGATGATGGCAAACAACCCAGAGGACTGGTTGAGTTTGTTGCTCAAACTAGAGAAAAACAGTGTTCCGCTAAGTGATGCTCTTTT
AAATAAATTGATTGGTCGTTACAGTCAAGCAATTGAAGCGCTTCCCCCAGATAAATATGGCCAAAATGAGAGTTTTGCTAGAATTCAAGT
GAGATTTGCTGAATTAAAAGCTATTCAAGAGCCAGATGATGCACGTGACTACTTTCAAATGGCCAGAGCAAACTGCAAGAAATTTGCTTT
TGTTCATATATCTTTTGCACAATTTGAACTGTCACAAGGTAATGTCAAAAAAAGTAAACAACTTCTTCAAAAAGCTGTAGAACGTGGAGC
AGTACCACTAGAAATGCTGGAAATTGCCCTGCGGAATTTAAACCTCCAAAAAAAGCAGCTGCTTTCAGAGGAGGAAAAGAAGAATTTATC
AGCATCTACGGTATTAACTGCCCAAGAATCATTTTCCGGTTCACTTGGGCATTTACAGAATAGGAACAACAGTTGTGATTCCAGAGGACA
GACTACTAAAGCCAGGTTTTTATATGGGTGTGTGTTCCTGCCCGACAACGGCGCCTTCTTCGTGAACTACGTCATTGCCTCAGCCTTTAT
CGGCAACGCCATGGACCTGCTGCGCATCCCAGGCCTGCTCATGTACATGATCCGGCTCTGCCTGGCGCGCTCGGCCGCCGAGAGGCGCAA
CGTGAAGCGGCATCAGGCCTACGAGTTCCAGTTTGGCGCAGCCTACGCCTGGATGATGTGCGTCTTCACGGTGGTCATGACCTACAGTAT
CACCTGCCCCATCATCGTGCCCTTCGGGCTCATGTACATGCTGCTGAAGCACCTGGTAGACAGGTACAATCTCTACTACGCCTACCTGCC
GGCCAAGCTGGACAAGAAGATCCACTCGGGGGCTGTGAACCAGGTGGTGGCCGCGCCCATCCTCTGCCTCTTCTGGCTGCTCTTCTTTTC
CACCATGCGCACGGGGTTCCTAGCTCCCACGTCTATGTTCACATTTGTGGTCCTGGTCATCACCATCGTCATCTGTCTCTGCCACGTCTG
CTTTGGACACTTCAAATACCTCAGTGCCCACAACTACAAGATTGAGCACACGGAGACAGATACTGTGGACCCCAGAAGCAATGGACGGCC
CCCCACTGCTGCTGCTGTCCCCAAATCTGCGAAATACATCGCTCAGGTGCTGCAGGACTCAGAGGTGGACGGGGATGGGGATGGGGCTCC
TGGGAGCTCAGGGGATGAGCCCCCATCATCCTCATCCCAAGATGAGGAGTTGCTGATGCCACCCGACGCCCTCACGGACACAGACTTCCA
GTCTTGCGAGGACAGCCTCATAGAGAATGAGATTCACCAGTAAGGGGAGGGAGGGGCCCTGGAGGCCACATCCTGCCCCACCCCACCCCC
ACTCCCACGGACACTAAAACGCTAATAATTTATTAGATCTAAAGCCCCTTCCTCCCCAGCCCCTGCTTTCATTAAGGTATTTAAACTTGG
GGGTTTCACTGCTCTCCCCCATGATGGAGGGAGGGAGCCCCCCAACCTCAGTGAGGAGAGCCCCGAGCCGGCCCCGGGGCAAAGAGGGGT
GCAGAGGGAGTTCCCCCAGATCAGTACCCCCCACCCCTCCCCAGCTAGTAGCATGACCAGGAGAGGGTTAATGAGAGCCAAGAGGAGTAC
CTGGTGCACCTGGTGCCGGTGGCTGGAGACCTGGGGGGCAGGTGGATCTGGGGCTGTTCCCCCCCCTCCGTTTTTTCCACCCCACAGTTC
CTCCTGGGATCTGGCCCTCCAGGGAAGTGGAGCCTCCAGCCCCTAGGGGATGCATGAGGGGGGAGGGGGTGCTGAGTGGGAGGAAGAGTC
AGGCTCACAGCTGGGGTGGCCTGGGGGTGGGGGTGGGCAAGGCTGACACTGGAAAATGGGTTTTTGCACTGTTTTTTTTTTGGTTTTTTT

>In-frame_ENST00000509894_ENST00000323267_TCGA-DX-A23Y-01A_TTK_chr6_80721265_+_TMEM63B_chr6_44119583_length(amino acids)=517AA_start in transcript=829_stop in transcript=2382
MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMANNPEDWLSLLLKLEKNSVPLSDALLNKLIGR
YSQAIEALPPDKYGQNESFARIQVRFAELKAIQEPDDARDYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEML
EIALRNLNLQKKQLLSEEEKKNLSASTVLTAQESFSGSLGHLQNRNNSCDSRGQTTKARFLYGCVFLPDNGAFFVNYVIASAFIGNAMDL
LRIPGLLMYMIRLCLARSAAERRNVKRHQAYEFQFGAAYAWMMCVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNLYYAYLPAKLDKK
IHSGAVNQVVAAPILCLFWLLFFSTMRTGFLAPTSMFTFVVLVITIVICLCHVCFGHFKYLSAHNYKIEHTETDTVDPRSNGRPPTAAAV

--------------------------------------------------------------
>In-frame_ENST00000230510_ENST00000259746_TCGA-DX-A23Y-01A_TTK_chr6_80721265_+_TMEM63B_chr6_44119583_length(transcript)=2771nt_BP=1309nt
AAAAAGCACTGAAATTCTTGAGCTGGCGGCAGGGCTGAACGTAGCTCAGTGAAAGATCCTTTCTTGCCACATCCTCTCTAAGCCAGGCTG
TGAGAACCGCGGGAAACGAAGGAGAAGGGTGGCGGTGGGGTCAGTAAAGGGCCGGCCCAAGGTGCATCTTTTAGGTCCTGATGCTAGGAG
CAGCCGTCCCTGCCCCTATATTCCTCTCACTGGGTAGGTTTGCTCGGGAGTGGCTACCTCCCAGGCAAAAATTCGGCCTGGTTAAACTGG
AAAGACCAGGAAAGCCCGCCCACGGGCGTCCGGGGAACGCCTGCAAAGTGCCAGCACCCTACCAACCCAGGCGCCGCACGGGTGGGGTCG
CGGCCGCAGGCTCTTCCGGGGCGGGCCTAGCCTGACGCAGGAGGAGGGGCGGCCCCCGTCGCACAAGAACCAATCACGACTGTCGCTTCT
ACGTGGCTAGCATTGACCAATAGGAGACCGTAGTGATAGCGACGGGGAAATTCAAACGTGTTTGCGGAAAGGAGTTTGGGTTCCATCTTT
TCATTTCCCCAGCGCAGCTTTCTGTAGTTTTTTTCTTAGAAATGGAATCCGAGGATTTAAGTGGCAGAGAATTGACAATTGATTCCATAA
TGAACAAAGTGAGAGACATTAAAAATAAGTTTAAAAATGAAGACCTTACTGATGAACTAAGCTTGAATAAAATTTCTGCTGATACTACAG
ATAACTCGGGAACTGTTAACCAAATTATGATGATGGCAAACAACCCAGAGGACTGGTTGAGTTTGTTGCTCAAACTAGAGAAAAACAGTG
TTCCGCTAAGTGATGCTCTTTTAAATAAATTGATTGGTCGTTACAGTCAAGCAATTGAAGCGCTTCCCCCAGATAAATATGGCCAAAATG
AGAGTTTTGCTAGAATTCAAGTGAGATTTGCTGAATTAAAAGCTATTCAAGAGCCAGATGATGCACGTGACTACTTTCAAATGGCCAGAG
CAAACTGCAAGAAATTTGCTTTTGTTCATATATCTTTTGCACAATTTGAACTGTCACAAGGTAATGTCAAAAAAAGTAAACAACTTCTTC
AAAAAGCTGTAGAACGTGGAGCAGTACCACTAGAAATGCTGGAAATTGCCCTGCGGAATTTAAACCTCCAAAAAAAGCAGCTGCTTTCAG
AGGAGGAAAAGAAGAATTTATCAGCATCTACGGTATTAACTGCCCAAGAATCATTTTCCGGTTCACTTGGGCATTTACAGAATAGGAACA
ACAGTTGTGATTCCAGAGGACAGACTACTAAAGCCAGGTTTTTATATGGGTGTGTGTTCCTGCCCGACAACGGCGCCTTCTTCGTGAACT
ACGTCATTGCCTCAGCCTTTATCGGCAACGCCATGGACCTGCTGCGCATCCCAGGCCTGCTCATGTACATGATCCGGCTCTGCCTGGCGC
GCTCGGCCGCCGAGAGGCGCAACGTGAAGCGGCATCAGGCCTACGAGTTCCAGTTTGGCGCAGCCTACGCCTGGATGATGTGCGTCTTCA
CGGTGGTCATGACCTACAGTATCACCTGCCCCATCATCGTGCCCTTCGGGCTCATGTACATGCTGCTGAAGCACCTGGTAGACAGGTACA
ATCTCTACTACGCCTACCTGCCGGCCAAGCTGGACAAGAAGATCCACTCGGGGGCTGTGAACCAGGTGGTGGCCGCGCCCATCCTCTGCC
TCTTCTGGCTGCTCTTCTTTTCCACCATGCGCACGGGGTTCCTAGCTCCCACGTCTATGTTCACATTTGTGGTCCTGGTCATCACCATCG
TCATCTGTCTCTGCCACGTCTGCTTTGGACACTTCAAATACCTCAGTGCCCACAACTACAAGATTGAGCACACGGAGACAGATACTGTGG
ACCCCAGAAGCAATGGACGGCCCCCCACTGCTGCTGCTGTCCCCAAATCTGCGAAATACATCGCTCAGGTGCTGCAGGACTCAGAGGTGG
ACGGGGATGGGGATGGGGCTCCTGGGAGCTCAGGGGATGAGCCCCCATCATCCTCATCCCAAGATGAGGAGTTGCTGATGCCACCCGACG
CCCTCACGGACACAGACTTCCAGTCTTGCGAGGACAGCCTCATAGAGAATGAGATTCACCAGTAAGGGGAGGGAGGGGCCCTGGAGGCCA
CATCCTGCCCCACCCCACCCCCACTCCCACGGACACTAAAACGCTAATAATTTATTAGATCTAAAGCCCCTTCCTCCCCAGCCCCTGCTT
TCATTAAGGTATTTAAACTTGGGGGTTTCACTGCTCTCCCCCATGATGGAGGGAGGGAGCCCCCCAACCTCAGTGAGGAGAGCCCCGAGC
CGGCCCCGGGGCAAAGAGGGGTGCAGAGGGAGTTCCCCCAGATCAGTACCCCCCACCCCTCCCCAGCTAGTAGCATGACCAGGAGAGGGT
TAATGAGAGCCAAGAGGAGTACCTGGTGCACCTGGTGCCGGTGGCTGGAGACCTGGGGGGCAGGTGGATCTGGGGCTGTTCCCCCCCCTC
CGTTTTTTCCACCCCACAGTTCCTCCTGGGATCTGGCCCTCCAGGGAAGTGGAGCCTCCAGCCCCTAGGGGATGCATGAGGGGGGAGGGG
GTGCTGAGTGGGAGGAAGAGTCAGGCTCACAGCTGGGGTGGCCTGGGGGTGGGGGTGGGCAAGGCTGACACTGGAAAATGGGTTTTTGCA

>In-frame_ENST00000230510_ENST00000259746_TCGA-DX-A23Y-01A_TTK_chr6_80721265_+_TMEM63B_chr6_44119583_length(amino acids)=517AA_start in transcript=581_stop in transcript=2134
MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMANNPEDWLSLLLKLEKNSVPLSDALLNKLIGR
YSQAIEALPPDKYGQNESFARIQVRFAELKAIQEPDDARDYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEML
EIALRNLNLQKKQLLSEEEKKNLSASTVLTAQESFSGSLGHLQNRNNSCDSRGQTTKARFLYGCVFLPDNGAFFVNYVIASAFIGNAMDL
LRIPGLLMYMIRLCLARSAAERRNVKRHQAYEFQFGAAYAWMMCVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNLYYAYLPAKLDKK
IHSGAVNQVVAAPILCLFWLLFFSTMRTGFLAPTSMFTFVVLVITIVICLCHVCFGHFKYLSAHNYKIEHTETDTVDPRSNGRPPTAAAV

--------------------------------------------------------------
>In-frame_ENST00000230510_ENST00000323267_TCGA-DX-A23Y-01A_TTK_chr6_80721265_+_TMEM63B_chr6_44119583_length(transcript)=2770nt_BP=1309nt
AAAAAGCACTGAAATTCTTGAGCTGGCGGCAGGGCTGAACGTAGCTCAGTGAAAGATCCTTTCTTGCCACATCCTCTCTAAGCCAGGCTG
TGAGAACCGCGGGAAACGAAGGAGAAGGGTGGCGGTGGGGTCAGTAAAGGGCCGGCCCAAGGTGCATCTTTTAGGTCCTGATGCTAGGAG
CAGCCGTCCCTGCCCCTATATTCCTCTCACTGGGTAGGTTTGCTCGGGAGTGGCTACCTCCCAGGCAAAAATTCGGCCTGGTTAAACTGG
AAAGACCAGGAAAGCCCGCCCACGGGCGTCCGGGGAACGCCTGCAAAGTGCCAGCACCCTACCAACCCAGGCGCCGCACGGGTGGGGTCG
CGGCCGCAGGCTCTTCCGGGGCGGGCCTAGCCTGACGCAGGAGGAGGGGCGGCCCCCGTCGCACAAGAACCAATCACGACTGTCGCTTCT
ACGTGGCTAGCATTGACCAATAGGAGACCGTAGTGATAGCGACGGGGAAATTCAAACGTGTTTGCGGAAAGGAGTTTGGGTTCCATCTTT
TCATTTCCCCAGCGCAGCTTTCTGTAGTTTTTTTCTTAGAAATGGAATCCGAGGATTTAAGTGGCAGAGAATTGACAATTGATTCCATAA
TGAACAAAGTGAGAGACATTAAAAATAAGTTTAAAAATGAAGACCTTACTGATGAACTAAGCTTGAATAAAATTTCTGCTGATACTACAG
ATAACTCGGGAACTGTTAACCAAATTATGATGATGGCAAACAACCCAGAGGACTGGTTGAGTTTGTTGCTCAAACTAGAGAAAAACAGTG
TTCCGCTAAGTGATGCTCTTTTAAATAAATTGATTGGTCGTTACAGTCAAGCAATTGAAGCGCTTCCCCCAGATAAATATGGCCAAAATG
AGAGTTTTGCTAGAATTCAAGTGAGATTTGCTGAATTAAAAGCTATTCAAGAGCCAGATGATGCACGTGACTACTTTCAAATGGCCAGAG
CAAACTGCAAGAAATTTGCTTTTGTTCATATATCTTTTGCACAATTTGAACTGTCACAAGGTAATGTCAAAAAAAGTAAACAACTTCTTC
AAAAAGCTGTAGAACGTGGAGCAGTACCACTAGAAATGCTGGAAATTGCCCTGCGGAATTTAAACCTCCAAAAAAAGCAGCTGCTTTCAG
AGGAGGAAAAGAAGAATTTATCAGCATCTACGGTATTAACTGCCCAAGAATCATTTTCCGGTTCACTTGGGCATTTACAGAATAGGAACA
ACAGTTGTGATTCCAGAGGACAGACTACTAAAGCCAGGTTTTTATATGGGTGTGTGTTCCTGCCCGACAACGGCGCCTTCTTCGTGAACT
ACGTCATTGCCTCAGCCTTTATCGGCAACGCCATGGACCTGCTGCGCATCCCAGGCCTGCTCATGTACATGATCCGGCTCTGCCTGGCGC
GCTCGGCCGCCGAGAGGCGCAACGTGAAGCGGCATCAGGCCTACGAGTTCCAGTTTGGCGCAGCCTACGCCTGGATGATGTGCGTCTTCA
CGGTGGTCATGACCTACAGTATCACCTGCCCCATCATCGTGCCCTTCGGGCTCATGTACATGCTGCTGAAGCACCTGGTAGACAGGTACA
ATCTCTACTACGCCTACCTGCCGGCCAAGCTGGACAAGAAGATCCACTCGGGGGCTGTGAACCAGGTGGTGGCCGCGCCCATCCTCTGCC
TCTTCTGGCTGCTCTTCTTTTCCACCATGCGCACGGGGTTCCTAGCTCCCACGTCTATGTTCACATTTGTGGTCCTGGTCATCACCATCG
TCATCTGTCTCTGCCACGTCTGCTTTGGACACTTCAAATACCTCAGTGCCCACAACTACAAGATTGAGCACACGGAGACAGATACTGTGG
ACCCCAGAAGCAATGGACGGCCCCCCACTGCTGCTGCTGTCCCCAAATCTGCGAAATACATCGCTCAGGTGCTGCAGGACTCAGAGGTGG
ACGGGGATGGGGATGGGGCTCCTGGGAGCTCAGGGGATGAGCCCCCATCATCCTCATCCCAAGATGAGGAGTTGCTGATGCCACCCGACG
CCCTCACGGACACAGACTTCCAGTCTTGCGAGGACAGCCTCATAGAGAATGAGATTCACCAGTAAGGGGAGGGAGGGGCCCTGGAGGCCA
CATCCTGCCCCACCCCACCCCCACTCCCACGGACACTAAAACGCTAATAATTTATTAGATCTAAAGCCCCTTCCTCCCCAGCCCCTGCTT
TCATTAAGGTATTTAAACTTGGGGGTTTCACTGCTCTCCCCCATGATGGAGGGAGGGAGCCCCCCAACCTCAGTGAGGAGAGCCCCGAGC
CGGCCCCGGGGCAAAGAGGGGTGCAGAGGGAGTTCCCCCAGATCAGTACCCCCCACCCCTCCCCAGCTAGTAGCATGACCAGGAGAGGGT
TAATGAGAGCCAAGAGGAGTACCTGGTGCACCTGGTGCCGGTGGCTGGAGACCTGGGGGGCAGGTGGATCTGGGGCTGTTCCCCCCCCTC
CGTTTTTTCCACCCCACAGTTCCTCCTGGGATCTGGCCCTCCAGGGAAGTGGAGCCTCCAGCCCCTAGGGGATGCATGAGGGGGGAGGGG
GTGCTGAGTGGGAGGAAGAGTCAGGCTCACAGCTGGGGTGGCCTGGGGGTGGGGGTGGGCAAGGCTGACACTGGAAAATGGGTTTTTGCA

>In-frame_ENST00000230510_ENST00000323267_TCGA-DX-A23Y-01A_TTK_chr6_80721265_+_TMEM63B_chr6_44119583_length(amino acids)=517AA_start in transcript=581_stop in transcript=2134
MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMANNPEDWLSLLLKLEKNSVPLSDALLNKLIGR
YSQAIEALPPDKYGQNESFARIQVRFAELKAIQEPDDARDYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEML
EIALRNLNLQKKQLLSEEEKKNLSASTVLTAQESFSGSLGHLQNRNNSCDSRGQTTKARFLYGCVFLPDNGAFFVNYVIASAFIGNAMDL
LRIPGLLMYMIRLCLARSAAERRNVKRHQAYEFQFGAAYAWMMCVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNLYYAYLPAKLDKK
IHSGAVNQVVAAPILCLFWLLFFSTMRTGFLAPTSMFTFVVLVITIVICLCHVCFGHFKYLSAHNYKIEHTETDTVDPRSNGRPPTAAAV

--------------------------------------------------------------
>In-frame_ENST00000369798_ENST00000259746_TCGA-DX-A23Y-01A_TTK_chr6_80721265_+_TMEM63B_chr6_44119583_length(transcript)=2301nt_BP=839nt
AGCATTGACCAATAGGAGACCGTAGTGATAGCGACGGGGAAATTCAAACGTGTTTGCGGAAAGGAGTTTGGGTTCCATCTTTTCATTTCC
CCAGCGCAGCTTTCTGTAGAAATGGAATCCGAGGATTTAAGTGGCAGAGAATTGACAATTGATTCCATAATGAACAAAGTGAGAGACATT
AAAAATAAGTTTAAAAATGAAGACCTTACTGATGAACTAAGCTTGAATAAAATTTCTGCTGATACTACAGATAACTCGGGAACTGTTAAC
CAAATTATGATGATGGCAAACAACCCAGAGGACTGGTTGAGTTTGTTGCTCAAACTAGAGAAAAACAGTGTTCCGCTAAGTGATGCTCTT
TTAAATAAATTGATTGGTCGTTACAGTCAAGCAATTGAAGCGCTTCCCCCAGATAAATATGGCCAAAATGAGAGTTTTGCTAGAATTCAA
GTGAGATTTGCTGAATTAAAAGCTATTCAAGAGCCAGATGATGCACGTGACTACTTTCAAATGGCCAGAGCAAACTGCAAGAAATTTGCT
TTTGTTCATATATCTTTTGCACAATTTGAACTGTCACAAGGTAATGTCAAAAAAAGTAAACAACTTCTTCAAAAAGCTGTAGAACGTGGA
GCAGTACCACTAGAAATGCTGGAAATTGCCCTGCGGAATTTAAACCTCCAAAAAAAGCAGCTGCTTTCAGAGGAGGAAAAGAAGAATTTA
TCAGCATCTACGGTATTAACTGCCCAAGAATCATTTTCCGGTTCACTTGGGCATTTACAGAATAGGAACAACAGTTGTGATTCCAGAGGA
CAGACTACTAAAGCCAGGTTTTTATATGGGTGTGTGTTCCTGCCCGACAACGGCGCCTTCTTCGTGAACTACGTCATTGCCTCAGCCTTT
ATCGGCAACGCCATGGACCTGCTGCGCATCCCAGGCCTGCTCATGTACATGATCCGGCTCTGCCTGGCGCGCTCGGCCGCCGAGAGGCGC
AACGTGAAGCGGCATCAGGCCTACGAGTTCCAGTTTGGCGCAGCCTACGCCTGGATGATGTGCGTCTTCACGGTGGTCATGACCTACAGT
ATCACCTGCCCCATCATCGTGCCCTTCGGGCTCATGTACATGCTGCTGAAGCACCTGGTAGACAGGTACAATCTCTACTACGCCTACCTG
CCGGCCAAGCTGGACAAGAAGATCCACTCGGGGGCTGTGAACCAGGTGGTGGCCGCGCCCATCCTCTGCCTCTTCTGGCTGCTCTTCTTT
TCCACCATGCGCACGGGGTTCCTAGCTCCCACGTCTATGTTCACATTTGTGGTCCTGGTCATCACCATCGTCATCTGTCTCTGCCACGTC
TGCTTTGGACACTTCAAATACCTCAGTGCCCACAACTACAAGATTGAGCACACGGAGACAGATACTGTGGACCCCAGAAGCAATGGACGG
CCCCCCACTGCTGCTGCTGTCCCCAAATCTGCGAAATACATCGCTCAGGTGCTGCAGGACTCAGAGGTGGACGGGGATGGGGATGGGGCT
CCTGGGAGCTCAGGGGATGAGCCCCCATCATCCTCATCCCAAGATGAGGAGTTGCTGATGCCACCCGACGCCCTCACGGACACAGACTTC
CAGTCTTGCGAGGACAGCCTCATAGAGAATGAGATTCACCAGTAAGGGGAGGGAGGGGCCCTGGAGGCCACATCCTGCCCCACCCCACCC
CCACTCCCACGGACACTAAAACGCTAATAATTTATTAGATCTAAAGCCCCTTCCTCCCCAGCCCCTGCTTTCATTAAGGTATTTAAACTT
GGGGGTTTCACTGCTCTCCCCCATGATGGAGGGAGGGAGCCCCCCAACCTCAGTGAGGAGAGCCCCGAGCCGGCCCCGGGGCAAAGAGGG
GTGCAGAGGGAGTTCCCCCAGATCAGTACCCCCCACCCCTCCCCAGCTAGTAGCATGACCAGGAGAGGGTTAATGAGAGCCAAGAGGAGT
ACCTGGTGCACCTGGTGCCGGTGGCTGGAGACCTGGGGGGCAGGTGGATCTGGGGCTGTTCCCCCCCCTCCGTTTTTTCCACCCCACAGT
TCCTCCTGGGATCTGGCCCTCCAGGGAAGTGGAGCCTCCAGCCCCTAGGGGATGCATGAGGGGGGAGGGGGTGCTGAGTGGGAGGAAGAG
TCAGGCTCACAGCTGGGGTGGCCTGGGGGTGGGGGTGGGCAAGGCTGACACTGGAAAATGGGTTTTTGCACTGTTTTTTTTTTGGTTTTT

>In-frame_ENST00000369798_ENST00000259746_TCGA-DX-A23Y-01A_TTK_chr6_80721265_+_TMEM63B_chr6_44119583_length(amino acids)=517AA_start in transcript=111_stop in transcript=1664
MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMANNPEDWLSLLLKLEKNSVPLSDALLNKLIGR
YSQAIEALPPDKYGQNESFARIQVRFAELKAIQEPDDARDYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEML
EIALRNLNLQKKQLLSEEEKKNLSASTVLTAQESFSGSLGHLQNRNNSCDSRGQTTKARFLYGCVFLPDNGAFFVNYVIASAFIGNAMDL
LRIPGLLMYMIRLCLARSAAERRNVKRHQAYEFQFGAAYAWMMCVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNLYYAYLPAKLDKK
IHSGAVNQVVAAPILCLFWLLFFSTMRTGFLAPTSMFTFVVLVITIVICLCHVCFGHFKYLSAHNYKIEHTETDTVDPRSNGRPPTAAAV

--------------------------------------------------------------
>In-frame_ENST00000369798_ENST00000323267_TCGA-DX-A23Y-01A_TTK_chr6_80721265_+_TMEM63B_chr6_44119583_length(transcript)=2300nt_BP=839nt
AGCATTGACCAATAGGAGACCGTAGTGATAGCGACGGGGAAATTCAAACGTGTTTGCGGAAAGGAGTTTGGGTTCCATCTTTTCATTTCC
CCAGCGCAGCTTTCTGTAGAAATGGAATCCGAGGATTTAAGTGGCAGAGAATTGACAATTGATTCCATAATGAACAAAGTGAGAGACATT
AAAAATAAGTTTAAAAATGAAGACCTTACTGATGAACTAAGCTTGAATAAAATTTCTGCTGATACTACAGATAACTCGGGAACTGTTAAC
CAAATTATGATGATGGCAAACAACCCAGAGGACTGGTTGAGTTTGTTGCTCAAACTAGAGAAAAACAGTGTTCCGCTAAGTGATGCTCTT
TTAAATAAATTGATTGGTCGTTACAGTCAAGCAATTGAAGCGCTTCCCCCAGATAAATATGGCCAAAATGAGAGTTTTGCTAGAATTCAA
GTGAGATTTGCTGAATTAAAAGCTATTCAAGAGCCAGATGATGCACGTGACTACTTTCAAATGGCCAGAGCAAACTGCAAGAAATTTGCT
TTTGTTCATATATCTTTTGCACAATTTGAACTGTCACAAGGTAATGTCAAAAAAAGTAAACAACTTCTTCAAAAAGCTGTAGAACGTGGA
GCAGTACCACTAGAAATGCTGGAAATTGCCCTGCGGAATTTAAACCTCCAAAAAAAGCAGCTGCTTTCAGAGGAGGAAAAGAAGAATTTA
TCAGCATCTACGGTATTAACTGCCCAAGAATCATTTTCCGGTTCACTTGGGCATTTACAGAATAGGAACAACAGTTGTGATTCCAGAGGA
CAGACTACTAAAGCCAGGTTTTTATATGGGTGTGTGTTCCTGCCCGACAACGGCGCCTTCTTCGTGAACTACGTCATTGCCTCAGCCTTT
ATCGGCAACGCCATGGACCTGCTGCGCATCCCAGGCCTGCTCATGTACATGATCCGGCTCTGCCTGGCGCGCTCGGCCGCCGAGAGGCGC
AACGTGAAGCGGCATCAGGCCTACGAGTTCCAGTTTGGCGCAGCCTACGCCTGGATGATGTGCGTCTTCACGGTGGTCATGACCTACAGT
ATCACCTGCCCCATCATCGTGCCCTTCGGGCTCATGTACATGCTGCTGAAGCACCTGGTAGACAGGTACAATCTCTACTACGCCTACCTG
CCGGCCAAGCTGGACAAGAAGATCCACTCGGGGGCTGTGAACCAGGTGGTGGCCGCGCCCATCCTCTGCCTCTTCTGGCTGCTCTTCTTT
TCCACCATGCGCACGGGGTTCCTAGCTCCCACGTCTATGTTCACATTTGTGGTCCTGGTCATCACCATCGTCATCTGTCTCTGCCACGTC
TGCTTTGGACACTTCAAATACCTCAGTGCCCACAACTACAAGATTGAGCACACGGAGACAGATACTGTGGACCCCAGAAGCAATGGACGG
CCCCCCACTGCTGCTGCTGTCCCCAAATCTGCGAAATACATCGCTCAGGTGCTGCAGGACTCAGAGGTGGACGGGGATGGGGATGGGGCT
CCTGGGAGCTCAGGGGATGAGCCCCCATCATCCTCATCCCAAGATGAGGAGTTGCTGATGCCACCCGACGCCCTCACGGACACAGACTTC
CAGTCTTGCGAGGACAGCCTCATAGAGAATGAGATTCACCAGTAAGGGGAGGGAGGGGCCCTGGAGGCCACATCCTGCCCCACCCCACCC
CCACTCCCACGGACACTAAAACGCTAATAATTTATTAGATCTAAAGCCCCTTCCTCCCCAGCCCCTGCTTTCATTAAGGTATTTAAACTT
GGGGGTTTCACTGCTCTCCCCCATGATGGAGGGAGGGAGCCCCCCAACCTCAGTGAGGAGAGCCCCGAGCCGGCCCCGGGGCAAAGAGGG
GTGCAGAGGGAGTTCCCCCAGATCAGTACCCCCCACCCCTCCCCAGCTAGTAGCATGACCAGGAGAGGGTTAATGAGAGCCAAGAGGAGT
ACCTGGTGCACCTGGTGCCGGTGGCTGGAGACCTGGGGGGCAGGTGGATCTGGGGCTGTTCCCCCCCCTCCGTTTTTTCCACCCCACAGT
TCCTCCTGGGATCTGGCCCTCCAGGGAAGTGGAGCCTCCAGCCCCTAGGGGATGCATGAGGGGGGAGGGGGTGCTGAGTGGGAGGAAGAG
TCAGGCTCACAGCTGGGGTGGCCTGGGGGTGGGGGTGGGCAAGGCTGACACTGGAAAATGGGTTTTTGCACTGTTTTTTTTTTGGTTTTT

>In-frame_ENST00000369798_ENST00000323267_TCGA-DX-A23Y-01A_TTK_chr6_80721265_+_TMEM63B_chr6_44119583_length(amino acids)=517AA_start in transcript=111_stop in transcript=1664
MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMANNPEDWLSLLLKLEKNSVPLSDALLNKLIGR
YSQAIEALPPDKYGQNESFARIQVRFAELKAIQEPDDARDYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEML
EIALRNLNLQKKQLLSEEEKKNLSASTVLTAQESFSGSLGHLQNRNNSCDSRGQTTKARFLYGCVFLPDNGAFFVNYVIASAFIGNAMDL
LRIPGLLMYMIRLCLARSAAERRNVKRHQAYEFQFGAAYAWMMCVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNLYYAYLPAKLDKK
IHSGAVNQVVAAPILCLFWLLFFSTMRTGFLAPTSMFTFVVLVITIVICLCHVCFGHFKYLSAHNYKIEHTETDTVDPRSNGRPPTAAAV

--------------------------------------------------------------
>In-frame_ENST00000509894_ENST00000259746_TCGA-DX-A23Y_TTK_chr6_80721265_+_TMEM63B_chr6_44119582_length(transcript)=3019nt_BP=1557nt
ACCACAAAGCCACTTAGCGGCAGAGCCTCGCACCCGCGAAGATTATTACTAGGGAGATGTTTTTACCCCTGAGGACACCTGAGCCCTTAA
GTGGGGCAGGCTTCGAGGGAGGGGGGCCGATAAGGCGACTTCAGACAGGGCAATCACGATGGGCGCTTGAGTTCTGCGCAGAATTTTGAC
AAGGGGGAGGGTCTTGGCTTGAAGACAGAGCGTGGAGTCATTTAAGGATAATGGAAGGGCATAAGCAGAAGCTCAAGGATAAAAAGCACT
GAAATTCTTGAGCTGGCGGCAGGGCTGAACGTAGCTCAGTGAAAGATCCTTTCTTGCCACATCCTCTCTAAGCCAGGCTGTGAGAACCGC
GGGAAACGAAGGAGAAGGGTGGCGGTGGGGTCAGTAAAGGGCCGGCCCAAGGTGCATCTTTTAGGTCCTGATGCTAGGAGCAGCCGTCCC
TGCCCCTATATTCCTCTCACTGGGTAGGTTTGCTCGGGAGTGGCTACCTCCCAGGCAAAAATTCGGCCTGGTTAAACTGGAAAGACCAGG
AAAGCCCGCCCACGGGCGTCCGGGGAACGCCTGCAAAGTGCCAGCACCCTACCAACCCAGGCGCCGCACGGGTGGGGTCGCGGCCGCAGG
CTCTTCCGGGGCGGGCCTAGCCTGACGCAGGAGGAGGGGCGGCCCCCGTCGCACAAGAACCAATCACGACTGTCGCTTCTACGTGGCTAG
CATTGACCAATAGGAGACCGTAGTGATAGCGACGGGGAAATTCAAACGTGTTTGCGGAAAGGAGTTTGGGTTCCATCTTTTCATTTCCCC
AGCGCAGCTTTCTGTAGAAATGGAATCCGAGGATTTAAGTGGCAGAGAATTGACAATTGATTCCATAATGAACAAAGTGAGAGACATTAA
AAATAAGTTTAAAAATGAAGACCTTACTGATGAACTAAGCTTGAATAAAATTTCTGCTGATACTACAGATAACTCGGGAACTGTTAACCA
AATTATGATGATGGCAAACAACCCAGAGGACTGGTTGAGTTTGTTGCTCAAACTAGAGAAAAACAGTGTTCCGCTAAGTGATGCTCTTTT
AAATAAATTGATTGGTCGTTACAGTCAAGCAATTGAAGCGCTTCCCCCAGATAAATATGGCCAAAATGAGAGTTTTGCTAGAATTCAAGT
GAGATTTGCTGAATTAAAAGCTATTCAAGAGCCAGATGATGCACGTGACTACTTTCAAATGGCCAGAGCAAACTGCAAGAAATTTGCTTT
TGTTCATATATCTTTTGCACAATTTGAACTGTCACAAGGTAATGTCAAAAAAAGTAAACAACTTCTTCAAAAAGCTGTAGAACGTGGAGC
AGTACCACTAGAAATGCTGGAAATTGCCCTGCGGAATTTAAACCTCCAAAAAAAGCAGCTGCTTTCAGAGGAGGAAAAGAAGAATTTATC
AGCATCTACGGTATTAACTGCCCAAGAATCATTTTCCGGTTCACTTGGGCATTTACAGAATAGGAACAACAGTTGTGATTCCAGAGGACA
GACTACTAAAGCCAGGTTTTTATATGGGTGTGTGTTCCTGCCCGACAACGGCGCCTTCTTCGTGAACTACGTCATTGCCTCAGCCTTTAT
CGGCAACGCCATGGACCTGCTGCGCATCCCAGGCCTGCTCATGTACATGATCCGGCTCTGCCTGGCGCGCTCGGCCGCCGAGAGGCGCAA
CGTGAAGCGGCATCAGGCCTACGAGTTCCAGTTTGGCGCAGCCTACGCCTGGATGATGTGCGTCTTCACGGTGGTCATGACCTACAGTAT
CACCTGCCCCATCATCGTGCCCTTCGGGCTCATGTACATGCTGCTGAAGCACCTGGTAGACAGGTACAATCTCTACTACGCCTACCTGCC
GGCCAAGCTGGACAAGAAGATCCACTCGGGGGCTGTGAACCAGGTGGTGGCCGCGCCCATCCTCTGCCTCTTCTGGCTGCTCTTCTTTTC
CACCATGCGCACGGGGTTCCTAGCTCCCACGTCTATGTTCACATTTGTGGTCCTGGTCATCACCATCGTCATCTGTCTCTGCCACGTCTG
CTTTGGACACTTCAAATACCTCAGTGCCCACAACTACAAGATTGAGCACACGGAGACAGATACTGTGGACCCCAGAAGCAATGGACGGCC
CCCCACTGCTGCTGCTGTCCCCAAATCTGCGAAATACATCGCTCAGGTGCTGCAGGACTCAGAGGTGGACGGGGATGGGGATGGGGCTCC
TGGGAGCTCAGGGGATGAGCCCCCATCATCCTCATCCCAAGATGAGGAGTTGCTGATGCCACCCGACGCCCTCACGGACACAGACTTCCA
GTCTTGCGAGGACAGCCTCATAGAGAATGAGATTCACCAGTAAGGGGAGGGAGGGGCCCTGGAGGCCACATCCTGCCCCACCCCACCCCC
ACTCCCACGGACACTAAAACGCTAATAATTTATTAGATCTAAAGCCCCTTCCTCCCCAGCCCCTGCTTTCATTAAGGTATTTAAACTTGG
GGGTTTCACTGCTCTCCCCCATGATGGAGGGAGGGAGCCCCCCAACCTCAGTGAGGAGAGCCCCGAGCCGGCCCCGGGGCAAAGAGGGGT
GCAGAGGGAGTTCCCCCAGATCAGTACCCCCCACCCCTCCCCAGCTAGTAGCATGACCAGGAGAGGGTTAATGAGAGCCAAGAGGAGTAC
CTGGTGCACCTGGTGCCGGTGGCTGGAGACCTGGGGGGCAGGTGGATCTGGGGCTGTTCCCCCCCCTCCGTTTTTTCCACCCCACAGTTC
CTCCTGGGATCTGGCCCTCCAGGGAAGTGGAGCCTCCAGCCCCTAGGGGATGCATGAGGGGGGAGGGGGTGCTGAGTGGGAGGAAGAGTC
AGGCTCACAGCTGGGGTGGCCTGGGGGTGGGGGTGGGCAAGGCTGACACTGGAAAATGGGTTTTTGCACTGTTTTTTTTTTGGTTTTTTT

>In-frame_ENST00000509894_ENST00000259746_TCGA-DX-A23Y_TTK_chr6_80721265_+_TMEM63B_chr6_44119582_length(amino acids)=517AA_start in transcript=829_stop in transcript=2382
MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMANNPEDWLSLLLKLEKNSVPLSDALLNKLIGR
YSQAIEALPPDKYGQNESFARIQVRFAELKAIQEPDDARDYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEML
EIALRNLNLQKKQLLSEEEKKNLSASTVLTAQESFSGSLGHLQNRNNSCDSRGQTTKARFLYGCVFLPDNGAFFVNYVIASAFIGNAMDL
LRIPGLLMYMIRLCLARSAAERRNVKRHQAYEFQFGAAYAWMMCVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNLYYAYLPAKLDKK
IHSGAVNQVVAAPILCLFWLLFFSTMRTGFLAPTSMFTFVVLVITIVICLCHVCFGHFKYLSAHNYKIEHTETDTVDPRSNGRPPTAAAV

--------------------------------------------------------------
>In-frame_ENST00000509894_ENST00000323267_TCGA-DX-A23Y_TTK_chr6_80721265_+_TMEM63B_chr6_44119582_length(transcript)=3018nt_BP=1557nt
ACCACAAAGCCACTTAGCGGCAGAGCCTCGCACCCGCGAAGATTATTACTAGGGAGATGTTTTTACCCCTGAGGACACCTGAGCCCTTAA
GTGGGGCAGGCTTCGAGGGAGGGGGGCCGATAAGGCGACTTCAGACAGGGCAATCACGATGGGCGCTTGAGTTCTGCGCAGAATTTTGAC
AAGGGGGAGGGTCTTGGCTTGAAGACAGAGCGTGGAGTCATTTAAGGATAATGGAAGGGCATAAGCAGAAGCTCAAGGATAAAAAGCACT
GAAATTCTTGAGCTGGCGGCAGGGCTGAACGTAGCTCAGTGAAAGATCCTTTCTTGCCACATCCTCTCTAAGCCAGGCTGTGAGAACCGC
GGGAAACGAAGGAGAAGGGTGGCGGTGGGGTCAGTAAAGGGCCGGCCCAAGGTGCATCTTTTAGGTCCTGATGCTAGGAGCAGCCGTCCC
TGCCCCTATATTCCTCTCACTGGGTAGGTTTGCTCGGGAGTGGCTACCTCCCAGGCAAAAATTCGGCCTGGTTAAACTGGAAAGACCAGG
AAAGCCCGCCCACGGGCGTCCGGGGAACGCCTGCAAAGTGCCAGCACCCTACCAACCCAGGCGCCGCACGGGTGGGGTCGCGGCCGCAGG
CTCTTCCGGGGCGGGCCTAGCCTGACGCAGGAGGAGGGGCGGCCCCCGTCGCACAAGAACCAATCACGACTGTCGCTTCTACGTGGCTAG
CATTGACCAATAGGAGACCGTAGTGATAGCGACGGGGAAATTCAAACGTGTTTGCGGAAAGGAGTTTGGGTTCCATCTTTTCATTTCCCC
AGCGCAGCTTTCTGTAGAAATGGAATCCGAGGATTTAAGTGGCAGAGAATTGACAATTGATTCCATAATGAACAAAGTGAGAGACATTAA
AAATAAGTTTAAAAATGAAGACCTTACTGATGAACTAAGCTTGAATAAAATTTCTGCTGATACTACAGATAACTCGGGAACTGTTAACCA
AATTATGATGATGGCAAACAACCCAGAGGACTGGTTGAGTTTGTTGCTCAAACTAGAGAAAAACAGTGTTCCGCTAAGTGATGCTCTTTT
AAATAAATTGATTGGTCGTTACAGTCAAGCAATTGAAGCGCTTCCCCCAGATAAATATGGCCAAAATGAGAGTTTTGCTAGAATTCAAGT
GAGATTTGCTGAATTAAAAGCTATTCAAGAGCCAGATGATGCACGTGACTACTTTCAAATGGCCAGAGCAAACTGCAAGAAATTTGCTTT
TGTTCATATATCTTTTGCACAATTTGAACTGTCACAAGGTAATGTCAAAAAAAGTAAACAACTTCTTCAAAAAGCTGTAGAACGTGGAGC
AGTACCACTAGAAATGCTGGAAATTGCCCTGCGGAATTTAAACCTCCAAAAAAAGCAGCTGCTTTCAGAGGAGGAAAAGAAGAATTTATC
AGCATCTACGGTATTAACTGCCCAAGAATCATTTTCCGGTTCACTTGGGCATTTACAGAATAGGAACAACAGTTGTGATTCCAGAGGACA
GACTACTAAAGCCAGGTTTTTATATGGGTGTGTGTTCCTGCCCGACAACGGCGCCTTCTTCGTGAACTACGTCATTGCCTCAGCCTTTAT
CGGCAACGCCATGGACCTGCTGCGCATCCCAGGCCTGCTCATGTACATGATCCGGCTCTGCCTGGCGCGCTCGGCCGCCGAGAGGCGCAA
CGTGAAGCGGCATCAGGCCTACGAGTTCCAGTTTGGCGCAGCCTACGCCTGGATGATGTGCGTCTTCACGGTGGTCATGACCTACAGTAT
CACCTGCCCCATCATCGTGCCCTTCGGGCTCATGTACATGCTGCTGAAGCACCTGGTAGACAGGTACAATCTCTACTACGCCTACCTGCC
GGCCAAGCTGGACAAGAAGATCCACTCGGGGGCTGTGAACCAGGTGGTGGCCGCGCCCATCCTCTGCCTCTTCTGGCTGCTCTTCTTTTC
CACCATGCGCACGGGGTTCCTAGCTCCCACGTCTATGTTCACATTTGTGGTCCTGGTCATCACCATCGTCATCTGTCTCTGCCACGTCTG
CTTTGGACACTTCAAATACCTCAGTGCCCACAACTACAAGATTGAGCACACGGAGACAGATACTGTGGACCCCAGAAGCAATGGACGGCC
CCCCACTGCTGCTGCTGTCCCCAAATCTGCGAAATACATCGCTCAGGTGCTGCAGGACTCAGAGGTGGACGGGGATGGGGATGGGGCTCC
TGGGAGCTCAGGGGATGAGCCCCCATCATCCTCATCCCAAGATGAGGAGTTGCTGATGCCACCCGACGCCCTCACGGACACAGACTTCCA
GTCTTGCGAGGACAGCCTCATAGAGAATGAGATTCACCAGTAAGGGGAGGGAGGGGCCCTGGAGGCCACATCCTGCCCCACCCCACCCCC
ACTCCCACGGACACTAAAACGCTAATAATTTATTAGATCTAAAGCCCCTTCCTCCCCAGCCCCTGCTTTCATTAAGGTATTTAAACTTGG
GGGTTTCACTGCTCTCCCCCATGATGGAGGGAGGGAGCCCCCCAACCTCAGTGAGGAGAGCCCCGAGCCGGCCCCGGGGCAAAGAGGGGT
GCAGAGGGAGTTCCCCCAGATCAGTACCCCCCACCCCTCCCCAGCTAGTAGCATGACCAGGAGAGGGTTAATGAGAGCCAAGAGGAGTAC
CTGGTGCACCTGGTGCCGGTGGCTGGAGACCTGGGGGGCAGGTGGATCTGGGGCTGTTCCCCCCCCTCCGTTTTTTCCACCCCACAGTTC
CTCCTGGGATCTGGCCCTCCAGGGAAGTGGAGCCTCCAGCCCCTAGGGGATGCATGAGGGGGGAGGGGGTGCTGAGTGGGAGGAAGAGTC
AGGCTCACAGCTGGGGTGGCCTGGGGGTGGGGGTGGGCAAGGCTGACACTGGAAAATGGGTTTTTGCACTGTTTTTTTTTTGGTTTTTTT

>In-frame_ENST00000509894_ENST00000323267_TCGA-DX-A23Y_TTK_chr6_80721265_+_TMEM63B_chr6_44119582_length(amino acids)=517AA_start in transcript=829_stop in transcript=2382
MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMANNPEDWLSLLLKLEKNSVPLSDALLNKLIGR
YSQAIEALPPDKYGQNESFARIQVRFAELKAIQEPDDARDYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEML
EIALRNLNLQKKQLLSEEEKKNLSASTVLTAQESFSGSLGHLQNRNNSCDSRGQTTKARFLYGCVFLPDNGAFFVNYVIASAFIGNAMDL
LRIPGLLMYMIRLCLARSAAERRNVKRHQAYEFQFGAAYAWMMCVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNLYYAYLPAKLDKK
IHSGAVNQVVAAPILCLFWLLFFSTMRTGFLAPTSMFTFVVLVITIVICLCHVCFGHFKYLSAHNYKIEHTETDTVDPRSNGRPPTAAAV

--------------------------------------------------------------
>In-frame_ENST00000230510_ENST00000259746_TCGA-DX-A23Y_TTK_chr6_80721265_+_TMEM63B_chr6_44119582_length(transcript)=2771nt_BP=1309nt
AAAAAGCACTGAAATTCTTGAGCTGGCGGCAGGGCTGAACGTAGCTCAGTGAAAGATCCTTTCTTGCCACATCCTCTCTAAGCCAGGCTG
TGAGAACCGCGGGAAACGAAGGAGAAGGGTGGCGGTGGGGTCAGTAAAGGGCCGGCCCAAGGTGCATCTTTTAGGTCCTGATGCTAGGAG
CAGCCGTCCCTGCCCCTATATTCCTCTCACTGGGTAGGTTTGCTCGGGAGTGGCTACCTCCCAGGCAAAAATTCGGCCTGGTTAAACTGG
AAAGACCAGGAAAGCCCGCCCACGGGCGTCCGGGGAACGCCTGCAAAGTGCCAGCACCCTACCAACCCAGGCGCCGCACGGGTGGGGTCG
CGGCCGCAGGCTCTTCCGGGGCGGGCCTAGCCTGACGCAGGAGGAGGGGCGGCCCCCGTCGCACAAGAACCAATCACGACTGTCGCTTCT
ACGTGGCTAGCATTGACCAATAGGAGACCGTAGTGATAGCGACGGGGAAATTCAAACGTGTTTGCGGAAAGGAGTTTGGGTTCCATCTTT
TCATTTCCCCAGCGCAGCTTTCTGTAGTTTTTTTCTTAGAAATGGAATCCGAGGATTTAAGTGGCAGAGAATTGACAATTGATTCCATAA
TGAACAAAGTGAGAGACATTAAAAATAAGTTTAAAAATGAAGACCTTACTGATGAACTAAGCTTGAATAAAATTTCTGCTGATACTACAG
ATAACTCGGGAACTGTTAACCAAATTATGATGATGGCAAACAACCCAGAGGACTGGTTGAGTTTGTTGCTCAAACTAGAGAAAAACAGTG
TTCCGCTAAGTGATGCTCTTTTAAATAAATTGATTGGTCGTTACAGTCAAGCAATTGAAGCGCTTCCCCCAGATAAATATGGCCAAAATG
AGAGTTTTGCTAGAATTCAAGTGAGATTTGCTGAATTAAAAGCTATTCAAGAGCCAGATGATGCACGTGACTACTTTCAAATGGCCAGAG
CAAACTGCAAGAAATTTGCTTTTGTTCATATATCTTTTGCACAATTTGAACTGTCACAAGGTAATGTCAAAAAAAGTAAACAACTTCTTC
AAAAAGCTGTAGAACGTGGAGCAGTACCACTAGAAATGCTGGAAATTGCCCTGCGGAATTTAAACCTCCAAAAAAAGCAGCTGCTTTCAG
AGGAGGAAAAGAAGAATTTATCAGCATCTACGGTATTAACTGCCCAAGAATCATTTTCCGGTTCACTTGGGCATTTACAGAATAGGAACA
ACAGTTGTGATTCCAGAGGACAGACTACTAAAGCCAGGTTTTTATATGGGTGTGTGTTCCTGCCCGACAACGGCGCCTTCTTCGTGAACT
ACGTCATTGCCTCAGCCTTTATCGGCAACGCCATGGACCTGCTGCGCATCCCAGGCCTGCTCATGTACATGATCCGGCTCTGCCTGGCGC
GCTCGGCCGCCGAGAGGCGCAACGTGAAGCGGCATCAGGCCTACGAGTTCCAGTTTGGCGCAGCCTACGCCTGGATGATGTGCGTCTTCA
CGGTGGTCATGACCTACAGTATCACCTGCCCCATCATCGTGCCCTTCGGGCTCATGTACATGCTGCTGAAGCACCTGGTAGACAGGTACA
ATCTCTACTACGCCTACCTGCCGGCCAAGCTGGACAAGAAGATCCACTCGGGGGCTGTGAACCAGGTGGTGGCCGCGCCCATCCTCTGCC
TCTTCTGGCTGCTCTTCTTTTCCACCATGCGCACGGGGTTCCTAGCTCCCACGTCTATGTTCACATTTGTGGTCCTGGTCATCACCATCG
TCATCTGTCTCTGCCACGTCTGCTTTGGACACTTCAAATACCTCAGTGCCCACAACTACAAGATTGAGCACACGGAGACAGATACTGTGG
ACCCCAGAAGCAATGGACGGCCCCCCACTGCTGCTGCTGTCCCCAAATCTGCGAAATACATCGCTCAGGTGCTGCAGGACTCAGAGGTGG
ACGGGGATGGGGATGGGGCTCCTGGGAGCTCAGGGGATGAGCCCCCATCATCCTCATCCCAAGATGAGGAGTTGCTGATGCCACCCGACG
CCCTCACGGACACAGACTTCCAGTCTTGCGAGGACAGCCTCATAGAGAATGAGATTCACCAGTAAGGGGAGGGAGGGGCCCTGGAGGCCA
CATCCTGCCCCACCCCACCCCCACTCCCACGGACACTAAAACGCTAATAATTTATTAGATCTAAAGCCCCTTCCTCCCCAGCCCCTGCTT
TCATTAAGGTATTTAAACTTGGGGGTTTCACTGCTCTCCCCCATGATGGAGGGAGGGAGCCCCCCAACCTCAGTGAGGAGAGCCCCGAGC
CGGCCCCGGGGCAAAGAGGGGTGCAGAGGGAGTTCCCCCAGATCAGTACCCCCCACCCCTCCCCAGCTAGTAGCATGACCAGGAGAGGGT
TAATGAGAGCCAAGAGGAGTACCTGGTGCACCTGGTGCCGGTGGCTGGAGACCTGGGGGGCAGGTGGATCTGGGGCTGTTCCCCCCCCTC
CGTTTTTTCCACCCCACAGTTCCTCCTGGGATCTGGCCCTCCAGGGAAGTGGAGCCTCCAGCCCCTAGGGGATGCATGAGGGGGGAGGGG
GTGCTGAGTGGGAGGAAGAGTCAGGCTCACAGCTGGGGTGGCCTGGGGGTGGGGGTGGGCAAGGCTGACACTGGAAAATGGGTTTTTGCA

>In-frame_ENST00000230510_ENST00000259746_TCGA-DX-A23Y_TTK_chr6_80721265_+_TMEM63B_chr6_44119582_length(amino acids)=517AA_start in transcript=581_stop in transcript=2134
MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMANNPEDWLSLLLKLEKNSVPLSDALLNKLIGR
YSQAIEALPPDKYGQNESFARIQVRFAELKAIQEPDDARDYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEML
EIALRNLNLQKKQLLSEEEKKNLSASTVLTAQESFSGSLGHLQNRNNSCDSRGQTTKARFLYGCVFLPDNGAFFVNYVIASAFIGNAMDL
LRIPGLLMYMIRLCLARSAAERRNVKRHQAYEFQFGAAYAWMMCVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNLYYAYLPAKLDKK
IHSGAVNQVVAAPILCLFWLLFFSTMRTGFLAPTSMFTFVVLVITIVICLCHVCFGHFKYLSAHNYKIEHTETDTVDPRSNGRPPTAAAV

--------------------------------------------------------------
>In-frame_ENST00000230510_ENST00000323267_TCGA-DX-A23Y_TTK_chr6_80721265_+_TMEM63B_chr6_44119582_length(transcript)=2770nt_BP=1309nt
AAAAAGCACTGAAATTCTTGAGCTGGCGGCAGGGCTGAACGTAGCTCAGTGAAAGATCCTTTCTTGCCACATCCTCTCTAAGCCAGGCTG
TGAGAACCGCGGGAAACGAAGGAGAAGGGTGGCGGTGGGGTCAGTAAAGGGCCGGCCCAAGGTGCATCTTTTAGGTCCTGATGCTAGGAG
CAGCCGTCCCTGCCCCTATATTCCTCTCACTGGGTAGGTTTGCTCGGGAGTGGCTACCTCCCAGGCAAAAATTCGGCCTGGTTAAACTGG
AAAGACCAGGAAAGCCCGCCCACGGGCGTCCGGGGAACGCCTGCAAAGTGCCAGCACCCTACCAACCCAGGCGCCGCACGGGTGGGGTCG
CGGCCGCAGGCTCTTCCGGGGCGGGCCTAGCCTGACGCAGGAGGAGGGGCGGCCCCCGTCGCACAAGAACCAATCACGACTGTCGCTTCT
ACGTGGCTAGCATTGACCAATAGGAGACCGTAGTGATAGCGACGGGGAAATTCAAACGTGTTTGCGGAAAGGAGTTTGGGTTCCATCTTT
TCATTTCCCCAGCGCAGCTTTCTGTAGTTTTTTTCTTAGAAATGGAATCCGAGGATTTAAGTGGCAGAGAATTGACAATTGATTCCATAA
TGAACAAAGTGAGAGACATTAAAAATAAGTTTAAAAATGAAGACCTTACTGATGAACTAAGCTTGAATAAAATTTCTGCTGATACTACAG
ATAACTCGGGAACTGTTAACCAAATTATGATGATGGCAAACAACCCAGAGGACTGGTTGAGTTTGTTGCTCAAACTAGAGAAAAACAGTG
TTCCGCTAAGTGATGCTCTTTTAAATAAATTGATTGGTCGTTACAGTCAAGCAATTGAAGCGCTTCCCCCAGATAAATATGGCCAAAATG
AGAGTTTTGCTAGAATTCAAGTGAGATTTGCTGAATTAAAAGCTATTCAAGAGCCAGATGATGCACGTGACTACTTTCAAATGGCCAGAG
CAAACTGCAAGAAATTTGCTTTTGTTCATATATCTTTTGCACAATTTGAACTGTCACAAGGTAATGTCAAAAAAAGTAAACAACTTCTTC
AAAAAGCTGTAGAACGTGGAGCAGTACCACTAGAAATGCTGGAAATTGCCCTGCGGAATTTAAACCTCCAAAAAAAGCAGCTGCTTTCAG
AGGAGGAAAAGAAGAATTTATCAGCATCTACGGTATTAACTGCCCAAGAATCATTTTCCGGTTCACTTGGGCATTTACAGAATAGGAACA
ACAGTTGTGATTCCAGAGGACAGACTACTAAAGCCAGGTTTTTATATGGGTGTGTGTTCCTGCCCGACAACGGCGCCTTCTTCGTGAACT
ACGTCATTGCCTCAGCCTTTATCGGCAACGCCATGGACCTGCTGCGCATCCCAGGCCTGCTCATGTACATGATCCGGCTCTGCCTGGCGC
GCTCGGCCGCCGAGAGGCGCAACGTGAAGCGGCATCAGGCCTACGAGTTCCAGTTTGGCGCAGCCTACGCCTGGATGATGTGCGTCTTCA
CGGTGGTCATGACCTACAGTATCACCTGCCCCATCATCGTGCCCTTCGGGCTCATGTACATGCTGCTGAAGCACCTGGTAGACAGGTACA
ATCTCTACTACGCCTACCTGCCGGCCAAGCTGGACAAGAAGATCCACTCGGGGGCTGTGAACCAGGTGGTGGCCGCGCCCATCCTCTGCC
TCTTCTGGCTGCTCTTCTTTTCCACCATGCGCACGGGGTTCCTAGCTCCCACGTCTATGTTCACATTTGTGGTCCTGGTCATCACCATCG
TCATCTGTCTCTGCCACGTCTGCTTTGGACACTTCAAATACCTCAGTGCCCACAACTACAAGATTGAGCACACGGAGACAGATACTGTGG
ACCCCAGAAGCAATGGACGGCCCCCCACTGCTGCTGCTGTCCCCAAATCTGCGAAATACATCGCTCAGGTGCTGCAGGACTCAGAGGTGG
ACGGGGATGGGGATGGGGCTCCTGGGAGCTCAGGGGATGAGCCCCCATCATCCTCATCCCAAGATGAGGAGTTGCTGATGCCACCCGACG
CCCTCACGGACACAGACTTCCAGTCTTGCGAGGACAGCCTCATAGAGAATGAGATTCACCAGTAAGGGGAGGGAGGGGCCCTGGAGGCCA
CATCCTGCCCCACCCCACCCCCACTCCCACGGACACTAAAACGCTAATAATTTATTAGATCTAAAGCCCCTTCCTCCCCAGCCCCTGCTT
TCATTAAGGTATTTAAACTTGGGGGTTTCACTGCTCTCCCCCATGATGGAGGGAGGGAGCCCCCCAACCTCAGTGAGGAGAGCCCCGAGC
CGGCCCCGGGGCAAAGAGGGGTGCAGAGGGAGTTCCCCCAGATCAGTACCCCCCACCCCTCCCCAGCTAGTAGCATGACCAGGAGAGGGT
TAATGAGAGCCAAGAGGAGTACCTGGTGCACCTGGTGCCGGTGGCTGGAGACCTGGGGGGCAGGTGGATCTGGGGCTGTTCCCCCCCCTC
CGTTTTTTCCACCCCACAGTTCCTCCTGGGATCTGGCCCTCCAGGGAAGTGGAGCCTCCAGCCCCTAGGGGATGCATGAGGGGGGAGGGG
GTGCTGAGTGGGAGGAAGAGTCAGGCTCACAGCTGGGGTGGCCTGGGGGTGGGGGTGGGCAAGGCTGACACTGGAAAATGGGTTTTTGCA

>In-frame_ENST00000230510_ENST00000323267_TCGA-DX-A23Y_TTK_chr6_80721265_+_TMEM63B_chr6_44119582_length(amino acids)=517AA_start in transcript=581_stop in transcript=2134
MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMANNPEDWLSLLLKLEKNSVPLSDALLNKLIGR
YSQAIEALPPDKYGQNESFARIQVRFAELKAIQEPDDARDYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEML
EIALRNLNLQKKQLLSEEEKKNLSASTVLTAQESFSGSLGHLQNRNNSCDSRGQTTKARFLYGCVFLPDNGAFFVNYVIASAFIGNAMDL
LRIPGLLMYMIRLCLARSAAERRNVKRHQAYEFQFGAAYAWMMCVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNLYYAYLPAKLDKK
IHSGAVNQVVAAPILCLFWLLFFSTMRTGFLAPTSMFTFVVLVITIVICLCHVCFGHFKYLSAHNYKIEHTETDTVDPRSNGRPPTAAAV

--------------------------------------------------------------
>In-frame_ENST00000369798_ENST00000259746_TCGA-DX-A23Y_TTK_chr6_80721265_+_TMEM63B_chr6_44119582_length(transcript)=2301nt_BP=839nt
AGCATTGACCAATAGGAGACCGTAGTGATAGCGACGGGGAAATTCAAACGTGTTTGCGGAAAGGAGTTTGGGTTCCATCTTTTCATTTCC
CCAGCGCAGCTTTCTGTAGAAATGGAATCCGAGGATTTAAGTGGCAGAGAATTGACAATTGATTCCATAATGAACAAAGTGAGAGACATT
AAAAATAAGTTTAAAAATGAAGACCTTACTGATGAACTAAGCTTGAATAAAATTTCTGCTGATACTACAGATAACTCGGGAACTGTTAAC
CAAATTATGATGATGGCAAACAACCCAGAGGACTGGTTGAGTTTGTTGCTCAAACTAGAGAAAAACAGTGTTCCGCTAAGTGATGCTCTT
TTAAATAAATTGATTGGTCGTTACAGTCAAGCAATTGAAGCGCTTCCCCCAGATAAATATGGCCAAAATGAGAGTTTTGCTAGAATTCAA
GTGAGATTTGCTGAATTAAAAGCTATTCAAGAGCCAGATGATGCACGTGACTACTTTCAAATGGCCAGAGCAAACTGCAAGAAATTTGCT
TTTGTTCATATATCTTTTGCACAATTTGAACTGTCACAAGGTAATGTCAAAAAAAGTAAACAACTTCTTCAAAAAGCTGTAGAACGTGGA
GCAGTACCACTAGAAATGCTGGAAATTGCCCTGCGGAATTTAAACCTCCAAAAAAAGCAGCTGCTTTCAGAGGAGGAAAAGAAGAATTTA
TCAGCATCTACGGTATTAACTGCCCAAGAATCATTTTCCGGTTCACTTGGGCATTTACAGAATAGGAACAACAGTTGTGATTCCAGAGGA
CAGACTACTAAAGCCAGGTTTTTATATGGGTGTGTGTTCCTGCCCGACAACGGCGCCTTCTTCGTGAACTACGTCATTGCCTCAGCCTTT
ATCGGCAACGCCATGGACCTGCTGCGCATCCCAGGCCTGCTCATGTACATGATCCGGCTCTGCCTGGCGCGCTCGGCCGCCGAGAGGCGC
AACGTGAAGCGGCATCAGGCCTACGAGTTCCAGTTTGGCGCAGCCTACGCCTGGATGATGTGCGTCTTCACGGTGGTCATGACCTACAGT
ATCACCTGCCCCATCATCGTGCCCTTCGGGCTCATGTACATGCTGCTGAAGCACCTGGTAGACAGGTACAATCTCTACTACGCCTACCTG
CCGGCCAAGCTGGACAAGAAGATCCACTCGGGGGCTGTGAACCAGGTGGTGGCCGCGCCCATCCTCTGCCTCTTCTGGCTGCTCTTCTTT
TCCACCATGCGCACGGGGTTCCTAGCTCCCACGTCTATGTTCACATTTGTGGTCCTGGTCATCACCATCGTCATCTGTCTCTGCCACGTC
TGCTTTGGACACTTCAAATACCTCAGTGCCCACAACTACAAGATTGAGCACACGGAGACAGATACTGTGGACCCCAGAAGCAATGGACGG
CCCCCCACTGCTGCTGCTGTCCCCAAATCTGCGAAATACATCGCTCAGGTGCTGCAGGACTCAGAGGTGGACGGGGATGGGGATGGGGCT
CCTGGGAGCTCAGGGGATGAGCCCCCATCATCCTCATCCCAAGATGAGGAGTTGCTGATGCCACCCGACGCCCTCACGGACACAGACTTC
CAGTCTTGCGAGGACAGCCTCATAGAGAATGAGATTCACCAGTAAGGGGAGGGAGGGGCCCTGGAGGCCACATCCTGCCCCACCCCACCC
CCACTCCCACGGACACTAAAACGCTAATAATTTATTAGATCTAAAGCCCCTTCCTCCCCAGCCCCTGCTTTCATTAAGGTATTTAAACTT
GGGGGTTTCACTGCTCTCCCCCATGATGGAGGGAGGGAGCCCCCCAACCTCAGTGAGGAGAGCCCCGAGCCGGCCCCGGGGCAAAGAGGG
GTGCAGAGGGAGTTCCCCCAGATCAGTACCCCCCACCCCTCCCCAGCTAGTAGCATGACCAGGAGAGGGTTAATGAGAGCCAAGAGGAGT
ACCTGGTGCACCTGGTGCCGGTGGCTGGAGACCTGGGGGGCAGGTGGATCTGGGGCTGTTCCCCCCCCTCCGTTTTTTCCACCCCACAGT
TCCTCCTGGGATCTGGCCCTCCAGGGAAGTGGAGCCTCCAGCCCCTAGGGGATGCATGAGGGGGGAGGGGGTGCTGAGTGGGAGGAAGAG
TCAGGCTCACAGCTGGGGTGGCCTGGGGGTGGGGGTGGGCAAGGCTGACACTGGAAAATGGGTTTTTGCACTGTTTTTTTTTTGGTTTTT

>In-frame_ENST00000369798_ENST00000259746_TCGA-DX-A23Y_TTK_chr6_80721265_+_TMEM63B_chr6_44119582_length(amino acids)=517AA_start in transcript=111_stop in transcript=1664
MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMANNPEDWLSLLLKLEKNSVPLSDALLNKLIGR
YSQAIEALPPDKYGQNESFARIQVRFAELKAIQEPDDARDYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEML
EIALRNLNLQKKQLLSEEEKKNLSASTVLTAQESFSGSLGHLQNRNNSCDSRGQTTKARFLYGCVFLPDNGAFFVNYVIASAFIGNAMDL
LRIPGLLMYMIRLCLARSAAERRNVKRHQAYEFQFGAAYAWMMCVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNLYYAYLPAKLDKK
IHSGAVNQVVAAPILCLFWLLFFSTMRTGFLAPTSMFTFVVLVITIVICLCHVCFGHFKYLSAHNYKIEHTETDTVDPRSNGRPPTAAAV

--------------------------------------------------------------
>In-frame_ENST00000369798_ENST00000323267_TCGA-DX-A23Y_TTK_chr6_80721265_+_TMEM63B_chr6_44119582_length(transcript)=2300nt_BP=839nt
AGCATTGACCAATAGGAGACCGTAGTGATAGCGACGGGGAAATTCAAACGTGTTTGCGGAAAGGAGTTTGGGTTCCATCTTTTCATTTCC
CCAGCGCAGCTTTCTGTAGAAATGGAATCCGAGGATTTAAGTGGCAGAGAATTGACAATTGATTCCATAATGAACAAAGTGAGAGACATT
AAAAATAAGTTTAAAAATGAAGACCTTACTGATGAACTAAGCTTGAATAAAATTTCTGCTGATACTACAGATAACTCGGGAACTGTTAAC
CAAATTATGATGATGGCAAACAACCCAGAGGACTGGTTGAGTTTGTTGCTCAAACTAGAGAAAAACAGTGTTCCGCTAAGTGATGCTCTT
TTAAATAAATTGATTGGTCGTTACAGTCAAGCAATTGAAGCGCTTCCCCCAGATAAATATGGCCAAAATGAGAGTTTTGCTAGAATTCAA
GTGAGATTTGCTGAATTAAAAGCTATTCAAGAGCCAGATGATGCACGTGACTACTTTCAAATGGCCAGAGCAAACTGCAAGAAATTTGCT
TTTGTTCATATATCTTTTGCACAATTTGAACTGTCACAAGGTAATGTCAAAAAAAGTAAACAACTTCTTCAAAAAGCTGTAGAACGTGGA
GCAGTACCACTAGAAATGCTGGAAATTGCCCTGCGGAATTTAAACCTCCAAAAAAAGCAGCTGCTTTCAGAGGAGGAAAAGAAGAATTTA
TCAGCATCTACGGTATTAACTGCCCAAGAATCATTTTCCGGTTCACTTGGGCATTTACAGAATAGGAACAACAGTTGTGATTCCAGAGGA
CAGACTACTAAAGCCAGGTTTTTATATGGGTGTGTGTTCCTGCCCGACAACGGCGCCTTCTTCGTGAACTACGTCATTGCCTCAGCCTTT
ATCGGCAACGCCATGGACCTGCTGCGCATCCCAGGCCTGCTCATGTACATGATCCGGCTCTGCCTGGCGCGCTCGGCCGCCGAGAGGCGC
AACGTGAAGCGGCATCAGGCCTACGAGTTCCAGTTTGGCGCAGCCTACGCCTGGATGATGTGCGTCTTCACGGTGGTCATGACCTACAGT
ATCACCTGCCCCATCATCGTGCCCTTCGGGCTCATGTACATGCTGCTGAAGCACCTGGTAGACAGGTACAATCTCTACTACGCCTACCTG
CCGGCCAAGCTGGACAAGAAGATCCACTCGGGGGCTGTGAACCAGGTGGTGGCCGCGCCCATCCTCTGCCTCTTCTGGCTGCTCTTCTTT
TCCACCATGCGCACGGGGTTCCTAGCTCCCACGTCTATGTTCACATTTGTGGTCCTGGTCATCACCATCGTCATCTGTCTCTGCCACGTC
TGCTTTGGACACTTCAAATACCTCAGTGCCCACAACTACAAGATTGAGCACACGGAGACAGATACTGTGGACCCCAGAAGCAATGGACGG
CCCCCCACTGCTGCTGCTGTCCCCAAATCTGCGAAATACATCGCTCAGGTGCTGCAGGACTCAGAGGTGGACGGGGATGGGGATGGGGCT
CCTGGGAGCTCAGGGGATGAGCCCCCATCATCCTCATCCCAAGATGAGGAGTTGCTGATGCCACCCGACGCCCTCACGGACACAGACTTC
CAGTCTTGCGAGGACAGCCTCATAGAGAATGAGATTCACCAGTAAGGGGAGGGAGGGGCCCTGGAGGCCACATCCTGCCCCACCCCACCC
CCACTCCCACGGACACTAAAACGCTAATAATTTATTAGATCTAAAGCCCCTTCCTCCCCAGCCCCTGCTTTCATTAAGGTATTTAAACTT
GGGGGTTTCACTGCTCTCCCCCATGATGGAGGGAGGGAGCCCCCCAACCTCAGTGAGGAGAGCCCCGAGCCGGCCCCGGGGCAAAGAGGG
GTGCAGAGGGAGTTCCCCCAGATCAGTACCCCCCACCCCTCCCCAGCTAGTAGCATGACCAGGAGAGGGTTAATGAGAGCCAAGAGGAGT
ACCTGGTGCACCTGGTGCCGGTGGCTGGAGACCTGGGGGGCAGGTGGATCTGGGGCTGTTCCCCCCCCTCCGTTTTTTCCACCCCACAGT
TCCTCCTGGGATCTGGCCCTCCAGGGAAGTGGAGCCTCCAGCCCCTAGGGGATGCATGAGGGGGGAGGGGGTGCTGAGTGGGAGGAAGAG
TCAGGCTCACAGCTGGGGTGGCCTGGGGGTGGGGGTGGGCAAGGCTGACACTGGAAAATGGGTTTTTGCACTGTTTTTTTTTTGGTTTTT

>In-frame_ENST00000369798_ENST00000323267_TCGA-DX-A23Y_TTK_chr6_80721265_+_TMEM63B_chr6_44119582_length(amino acids)=517AA_start in transcript=111_stop in transcript=1664
MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMANNPEDWLSLLLKLEKNSVPLSDALLNKLIGR
YSQAIEALPPDKYGQNESFARIQVRFAELKAIQEPDDARDYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEML
EIALRNLNLQKKQLLSEEEKKNLSASTVLTAQESFSGSLGHLQNRNNSCDSRGQTTKARFLYGCVFLPDNGAFFVNYVIASAFIGNAMDL
LRIPGLLMYMIRLCLARSAAERRNVKRHQAYEFQFGAAYAWMMCVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNLYYAYLPAKLDKK
IHSGAVNQVVAAPILCLFWLLFFSTMRTGFLAPTSMFTFVVLVITIVICLCHVCFGHFKYLSAHNYKIEHTETDTVDPRSNGRPPTAAAV

--------------------------------------------------------------

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Fusion Gene PPI Analysis for TTK-TMEM63B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TTK-TMEM63B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TTK-TMEM63B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneTTKC0032460Polycystic Ovary Syndrome1CTD_human
HgeneTTKC1136382Sclerocystic Ovaries1CTD_human
HgeneTTKC2239176Liver carcinoma1CTD_human