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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:UBA1-RAB3GAP2 (FusionGDB2 ID:95140) |
Fusion Gene Summary for UBA1-RAB3GAP2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: UBA1-RAB3GAP2 | Fusion gene ID: 95140 | Hgene | Tgene | Gene symbol | UBA1 | RAB3GAP2 | Gene ID | 7317 | 25782 |
| Gene name | ubiquitin like modifier activating enzyme 1 | RAB3 GTPase activating non-catalytic protein subunit 2 | |
| Synonyms | A1S9|A1S9T|A1ST|AMCX1|CFAP124|GXP1|POC20|SMAX2|UBA1A|UBE1|UBE1X | RAB3-GAP150|RAB3GAP150|SPG69|WARBM2|p150 | |
| Cytomap | Xp11.3 | 1q41 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ubiquitin-like modifier-activating enzyme 1A1S9T and BN75 temperature sensitivity complementingPOC20 centriolar protein homologUBA1, ubiquitin-activating enzyme E1 homolog Atesticular secretory protein Li 63 | rab3 GTPase-activating protein non-catalytic subunitRAB3 GTPase activating protein subunit 2 (non-catalytic)RGAP-isorab3 GTPase-activating protein 150 kDa subunitrab3-GAP p150rab3-GAP regulatory subunit | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000377351, ENST00000335972, ENST00000490869, ENST00000377269, | ENST00000358951, ENST00000462353, | |
| Fusion gene scores | * DoF score | 10 X 10 X 5=500 | 11 X 15 X 5=825 |
| # samples | 11 | 15 | |
| ** MAII score | log2(11/500*10)=-2.18442457113743 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(15/825*10)=-2.4594316186373 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: UBA1 [Title/Abstract] AND RAB3GAP2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | UBA1(47071866)-RAB3GAP2(220326669), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | UBA1 | GO:0006974 | cellular response to DNA damage stimulus | 22456334 |
| Fusion gene breakpoints across UBA1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene breakpoints across RAB3GAP2 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | Non-Cancer | ERR315385 | UBA1 | chrX | 47071866 | + | RAB3GAP2 | chr1 | 220326669 | - |
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Fusion Gene ORF analysis for UBA1-RAB3GAP2 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000377351 | ENST00000358951 | UBA1 | chrX | 47071866 | + | RAB3GAP2 | chr1 | 220326669 | - |
| 5CDS-intron | ENST00000377351 | ENST00000462353 | UBA1 | chrX | 47071866 | + | RAB3GAP2 | chr1 | 220326669 | - |
| In-frame | ENST00000335972 | ENST00000358951 | UBA1 | chrX | 47071866 | + | RAB3GAP2 | chr1 | 220326669 | - |
| 5CDS-intron | ENST00000335972 | ENST00000462353 | UBA1 | chrX | 47071866 | + | RAB3GAP2 | chr1 | 220326669 | - |
| intron-3CDS | ENST00000490869 | ENST00000358951 | UBA1 | chrX | 47071866 | + | RAB3GAP2 | chr1 | 220326669 | - |
| intron-intron | ENST00000490869 | ENST00000462353 | UBA1 | chrX | 47071866 | + | RAB3GAP2 | chr1 | 220326669 | - |
| In-frame | ENST00000377269 | ENST00000358951 | UBA1 | chrX | 47071866 | + | RAB3GAP2 | chr1 | 220326669 | - |
| 5CDS-intron | ENST00000377269 | ENST00000462353 | UBA1 | chrX | 47071866 | + | RAB3GAP2 | chr1 | 220326669 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000377351 | UBA1 | chrX | 47071866 | + | ENST00000358951 | RAB3GAP2 | chr1 | 220326669 | - | 6015 | 2599 | 30 | 2588 | 852 |
| ENST00000335972 | UBA1 | chrX | 47071866 | + | ENST00000358951 | RAB3GAP2 | chr1 | 220326669 | - | 6108 | 2692 | 150 | 2681 | 843 |
| ENST00000377269 | UBA1 | chrX | 47071866 | + | ENST00000358951 | RAB3GAP2 | chr1 | 220326669 | - | 5048 | 1632 | 779 | 1621 | 280 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000377351 | ENST00000358951 | UBA1 | chrX | 47071866 | + | RAB3GAP2 | chr1 | 220326669 | - | 0.00025569 | 0.99974436 |
| ENST00000335972 | ENST00000358951 | UBA1 | chrX | 47071866 | + | RAB3GAP2 | chr1 | 220326669 | - | 0.000271956 | 0.999728 |
| ENST00000377269 | ENST00000358951 | UBA1 | chrX | 47071866 | + | RAB3GAP2 | chr1 | 220326669 | - | 0.028194936 | 0.9718051 |
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Fusion Genomic Features for UBA1-RAB3GAP2 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for UBA1-RAB3GAP2 |
| Go to FGviewer for the breakpoints of chrX:47071866-chr1:220326669 - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes. | FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | UBA1 | chrX:47071866 | chr1:220326669 | ENST00000335972 | + | 1 | 26 | 5_11 | 0 | 1059.0 | Motif | Note=Nuclear localization signal |
| Hgene | UBA1 | chrX:47071866 | chr1:220326669 | ENST00000377351 | + | 1 | 26 | 5_11 | 0 | 1059.0 | Motif | Note=Nuclear localization signal |
| Hgene | UBA1 | chrX:47071866 | chr1:220326669 | ENST00000335972 | + | 1 | 26 | 576_577 | 0 | 1059.0 | Nucleotide binding | ATP |
| Hgene | UBA1 | chrX:47071866 | chr1:220326669 | ENST00000377351 | + | 1 | 26 | 576_577 | 0 | 1059.0 | Nucleotide binding | ATP |
| Hgene | UBA1 | chrX:47071866 | chr1:220326669 | ENST00000335972 | + | 1 | 26 | 63_611 | 0 | 1059.0 | Region | Note=2 approximate repeats |
| Hgene | UBA1 | chrX:47071866 | chr1:220326669 | ENST00000377351 | + | 1 | 26 | 63_611 | 0 | 1059.0 | Region | Note=2 approximate repeats |
| Hgene | UBA1 | chrX:47071866 | chr1:220326669 | ENST00000335972 | + | 1 | 26 | 459_611 | 0 | 1059.0 | Repeat | Note=1-2 |
| Hgene | UBA1 | chrX:47071866 | chr1:220326669 | ENST00000335972 | + | 1 | 26 | 63_199 | 0 | 1059.0 | Repeat | Note=1-1 |
| Hgene | UBA1 | chrX:47071866 | chr1:220326669 | ENST00000377351 | + | 1 | 26 | 459_611 | 0 | 1059.0 | Repeat | Note=1-2 |
| Hgene | UBA1 | chrX:47071866 | chr1:220326669 | ENST00000377351 | + | 1 | 26 | 63_199 | 0 | 1059.0 | Repeat | Note=1-1 |
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Fusion Gene Sequence for UBA1-RAB3GAP2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >In-frame_ENST00000377351_ENST00000358951_ERR315385_UBA1_chrX_47071866_+_RAB3GAP2_chr1_220326669_length(transcript)=6015nt_BP=2599nt CTTGTACGACAGAGGTGGTTTGCTCTTCCGTTGCCCCGTGGCTTCAGCTCATCTTTGGCAGGAAGGCGAGGCTTCCGCCCGGCACAGGGG ATGTCCAGCTCGCCGCTGTCCAAGAAACGTCGCGTGTCCGGGCCTGATCCAAAGCCGGGTTCTAACTGCTCCCCTGCCCAGTCCGTGTTG TCCGAAGTGCCCTCGGTGCCAACCAACGGAATGGCCAAGAACGGCAGTGAAGCAGACATAGACGAGGGCCTTTACTCCCGGCAGCTGTAT GTGTTGGGCCATGAGGCAATGAAGCGGCTCCAGACATCCAGTGTCCTGGTATCAGGCCTGCGGGGCCTGGGCGTGGAGATCGCTAAGAAC ATCATCCTTGGTGGGGTCAAGGCTGTTACCCTACATGACCAGGGCACTGCCCAGTGGGCTGATCTTTCCTCCCAGTTCTACCTGCGGGAG GAGGACATCGGTAAAAACCGGGCCGAGGTATCACAGCCCCGCCTCGCTGAGCTCAACAGCTATGTGCCTGTCACTGCCTACACTGGACCC CTCGTTGAGGACTTCCTTAGTGGTTTCCAGGTGGTGGTGCTCACCAACACCCCCCTGGAGGACCAGCTGCGAGTGGGTGAGTTCTGTCAC AACCGTGGCATCAAGCTGGTGGTGGCAGACACGCGGGGCCTGTTTGGGCAGCTCTTCTGTGACTTTGGAGAGGAAATGATCCTCACAGAT TCCAATGGGGAGCAGCCACTCAGTGCTATGGTTTCTATGGTTACCAAGGACAACCCCGGTGTGGTTACCTGCCTGGATGAGGCCCGACAC GGGTTTGAGAGCGGGGACTTTGTCTCCTTTTCAGAAGTACAGGGCATGGTTGAACTCAACGGAAATCAGCCCATGGAGATCAAAGTCCTG GGTCCTTATACCTTTAGCATCTGTGACACCTCCAACTTCTCCGACTACATCCGTGGAGGCATCGTCAGTCAGGTCAAAGTACCTAAGAAG ATTAGCTTTAAATCCTTGGTGGCCTCACTGGCAGAACCTGACTTTGTGGTGACGGACTTCGCCAAGTTTTCTCGCCCTGCCCAGCTGCAC ATTGGCTTCCAGGCCCTGCACCAGTTCTGTGCTCAGCATGGCCGGCCACCTCGGCCCCGCAATGAGGAGGATGCAGCAGAACTGGTAGCC TTAGCACAGGCTGTGAATGCTCGAGCCCTGCCAGCAGTGCAGCAAAATAACCTGGACGAGGACCTCATCCGGAAGCTGGCATATGTGGCT GCTGGGGATCTGGCACCCATAAACGCCTTCATTGGGGGCCTGGCTGCCCAGGAAGTCATGAAGGCCTGCTCCGGGAAGTTCATGCCCATC ATGCAGTGGCTATACTTTGATGCCCTTGAGTGTCTCCCTGAGGACAAAGAGGTCCTCACAGAGGACAAGTGCCTCCAGCGCCAGAACCGT TATGACGGGCAAGTGGCTGTGTTTGGCTCAGACCTGCAAGAGAAGCTGGGCAAGCAGAAGTATTTCCTGGTGGGTGCGGGGGCCATTGGC TGTGAGCTGCTCAAGAACTTTGCCATGATTGGGCTGGGCTGCGGGGAGGGTGGAGAAATCATCGTTACAGACATGGACACCATTGAGAAG TCAAATCTGAATCGACAGTTTCTTTTCCGGCCCTGGGATGTCACGAAGTTAAAGTCTGACACGGCTGCTGCAGCTGTGCGCCAAATGAAT CCACATATCCGGGTGACAAGCCACCAGAACCGTGTGGGTCCTGACACGGAGCGCATCTATGATGACGATTTTTTCCAAAACCTAGATGGC GTGGCCAATGCCCTGGACAACGTGGATGCCCGCATGTACATGGACCGCCGCTGTGTCTACTACCGGAAGCCACTGCTGGAGTCAGGCACA CTGGGCACCAAAGGCAATGTGCAGGTGGTGATCCCCTTCCTGACAGAGTCGTACAGTTCCAGCCAGGACCCACCTGAGAAGTCCATCCCC ATCTGTACCCTGAAGAACTTCCCTAATGCCATCGAGCACACCCTGCAGTGGGCTCGGGATGAGTTTGAAGGCCTCTTCAAGCAGCCAGCA GAAAATGTCAACCAGTACCTCACAGACCCCAAGTTTGTGGAGCGAACACTGCGGCTGGCAGGCACTCAGCCCTTGGAGGTGCTGGAGGCT GTGCAGCGCAGCCTGGTGCTGCAGCGACCACAGACCTGGGCTGACTGCGTGACCTGGGCCTGCCACCACTGGCACACCCAGTACTCGAAC AACATCCGGCAGCTGCTGCACAACTTCCCTCCTGACCAGCTCACAAGCTCAGGAGCGCCGTTCTGGTCTGGGCCCAAACGCTGTCCACAC CCGCTCACCTTTGATGTCAACAATCCCCTGCATCTGGACTATGTGATGGCTGCTGCCAACCTGTTTGCCCAGACCTACGGGCTGACAGGC TCTCAGGACCGAGCTGCTGTGGCCACATTCCTGCAGTCTGTGCAGGTCCCCGAATTCACCCCCAAGTCTGGCGTCAAGATCCATGTTTCT GACCAGGAGCTGCAGAGCGCCAATGCCTCTGTTGGACAAGCTCCCTGGATTCAAGATGTACCCCATTGACTTTGAGAAGGACCCCCAGGA CCTTCAAAACACTGAAGTGCCAATTGCAACAACAGCTAAACTAGTAAATAAAGTAATTGAGCTTTTACCAGAAAAACATGGGCAATATGG TCTAGCCTTACACCTCATTGAAGCTGTGGAAGCCATATCTCTTCCTTCTTTATGACACTTACCTACTGGAAATAGTCTAAAATTATGATT ATAACATGAAGTAGTGCATGGTTATTTTACATAGTAAGACCTGGAATTTTATGGGAAAAGTATGTCTTTTTTTTTCCTTTTGTAAAATAA ATAAAAGTATATACAACTTTTAAAAAGTGCAACCCTGGCTAAATTCCACTCCTTTGGTTAATACTGAAGATAAAATATAAACAAATGTCA ACTCTGTTATAATTAATACAGATGTTTTACTGTTTATTTCTAATTCAAACACTTAAGTAGCTTTATTGTTAAACTTTGCTATTTAAAATT GGTTATAATTTAGATTATGTTCTTATAAGATTCTATATTTCCTATCTAAAATGTTGTTGTAATTCAATTTAAATGTGTTCATGTACAGTC CCCATCAGTAGCGTATAGAACACCCCACTCTCCTTTAGTAAATGTTGAGAAAATGCCTTTGTTGTCATGCTCCAAATCCCACACTGGGCT GCCACCTGGGAGTTCTGGATACCGAAAGGTTCCTTTCCCAGAGGTTCTGCTGTTGCCATCAGAGGAGGATGACCGTGCTTGAGGAGGAAG AATGGGTTCAAGATCATCATATTCATCAGAAGGGGACACTAAATAGAACCCTTAACCTGTTGTACTTGCCAAAATTGAGAATCAGAGATG TGTAAAATGCAGCAAATTAATTATAATGTAAGTTAAGATTTGCTTTTTGCCAAGTTGCAAAGTTGTATCCACATCAGGTCACTGTAAAAA TGTATTATCTTGTAAAACTTATGTAAAAAAAAAAAAAAAAAAAAGGCAAAGATACTAAAAATTTTAAGTCCGACTTTATTTTTCCTACAA GTGTTTAGAAATGCTTCTGGGATTTGCTAATATTATCTGTCCTTGGGAACAGTATTGAAAAAACTGCTTAGTGGTATTACAGCTTTAGCA AACCTACCTCACAGCTGGGATGAGAGGATAAAATACAACTAATTTTGTACCCTATAGTGCCTAGAGCAGTCCAAGTGCTAAATAAATATT TACTGATTAAAACCAAACTATAGCTACTCGGGAGGCTGGAGGAGGATCGCTTGAGCCCAGGAGTTTGAGGCCATTCTGGGCAATATAGCA AGACCCTGTCTCGAAAAAAAAAAAAAAAAGAAAAAACCAAACTAACCAAAACTCTGTAAAAGAGTGCTTTGAGCTCTACAAATACCAAGT ATTTATTGTGGTATATTTTTAGAATGTAGCCATACAGTGTAATTATGGGTATCTGTCATGGATCACAATTATTATTCATAGTAAGTCATT GTGATACAGAAGTTTGTTTCTTCACTTCCCCTTAAGAAGCCAACTATAGTAATCATGCAAAGTTGAGGAGTATGTCCTTCAGGGATATAA AAAGAAAAACAAATCTGTTTTTTGAGCTAAAAGAGCACATCCAAACAAGAATTTAACTGGCTAAAATTTAGTAATTACTGTTAAGTAACT ATCAAACTTGAAATCTTACAAGATAAATGGTTAAGATGTCTTGAGTATTTGGGATGGGGGCCTGTGAGTCTGATTGAGACATACATTTTA CAGAGTAGCAGCACTGGAAAGGGCTAGTCCAACCTCCCAGCCTCTGCTTGGGTCTCCGCTGCCCCAGCCACACACATCCTAGAATTCTTG TAAACATATCTGGCTCTGTGTTAACAGTCACTTGTTATATGTTTTCTAAGAGATTAGTTCTTCCTGTGATTTTTCCAAGTACGCTGAAAG TAGTAGTATGAACTTAAGGAGGCTAGTCAAAGAAACTTGGAGTTATAGGTATTTTTAAAGAATAAATCCTCAATTCCATCATCACTTGGC GGGGAGGGGGCACTTATTAAGCATTTTAGATAATAAAACTGGTTAAGCTTACTCTGGTAGAACAGACAATCAAATCTGGGGATTGCTGAG AACAATAATAAGCTGAAGTATGGCTCACAGAATCCTAACACAAATCATTAAGTCTCTAGTTAGATTTGTTATCCTAAAATTTTTCATAGA ATTTTAAAATCTAATTCTGACTTGTATGGTTAAGAAAAGCAGTTAAATATTTTACTACTTATCAAGGGCTTTTAAAATAAATAAATCTGA TTGATAGGAAGAAAGGCAAATAAATACCTATGTAGACATTCTATAATAACAAAGAGCCATAGATGATAAAGGAATTAGATTTTAATGTAG AATGGGTGGTTTCTGAAACAAAGGTATGTGGTACTTTGTAGTTATTGATGAGAAGCCAGTAACCAGTAGTGTTTTCCTAGATATATGCCC ACCCTCACACAACTTTCTTCATTAACAAACATTAAATATGCATTTGTATCTTATTAAATTATATTGTATAATGCTGAAGGAAAACAAAAA GTGTTCAAATAATCATAACTTCTACATTACAGGTTCTGTTTAGATGCAGAACTAGAGGGGCCAGGGTAAATGTAGATAAAGAGATATATA GCACCATGCTTCTTAATGCTTCATACTTTTGCAAACAGAAAAAAAAAGTTTTACTTTTATTATAAAACTTCATCTATGGTCAAAGTAAAC ACTGTTACATTTAAATTGCTTTTTAAAAACAATTGCGATCTAAAAAGTCAAAAATCTGAAATTTAATAATATGAGACTTACACTGAATAT AATGTTCATTTAGAAGTTGCTGTGGTCCACTTCATTTATAAGGAACAAATATTTTTACAGTACACTATAGCAACAGCAAAAGCCCTCTCT CACCCTGATAGGAATGGGTTTGCTGGGTGTCTAGAAGTTAGATTCCTGCTGAATAGAATTAGCCATCCTTAAAAGATTTTAATCCAATAC TGAACTGTTTATAAAATGCTTTCTCTATTGTAATGTACTGTAAGTAGTGAAATTCTGTATATACTGCTATTTTCTGTCTGTTCATTGTTG TGAACTTCTTATGTATATTAGTGAAATAAATTTTCAGCTTTCAGCCATTCTACAGGTTCATGACAAAGAGGTCCTTGCCTCTCAGCTGCT GGTGCTCACGGGGCAAAGGCTGGCTCATGCGCTTCTCCACACCCAGACAAAAGAAGGAATGGAGCTGCTTGCCAGACTTCCACCCACACT GTGTACTTGGCTGAAAGCAATGCACCCACTCCTTTTGGGAAAGACCAAGATTGGCCAGCTCTAGCTGTGGATTTAGCCCATCACCTTCAA >In-frame_ENST00000377351_ENST00000358951_ERR315385_UBA1_chrX_47071866_+_RAB3GAP2_chr1_220326669_length(amino acids)=852AA_start in transcript=30_stop in transcript=2588 MPRGFSSSLAGRRGFRPAQGMSSSPLSKKRRVSGPDPKPGSNCSPAQSVLSEVPSVPTNGMAKNGSEADIDEGLYSRQLYVLGHEAMKRL QTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVEDFLSGFQ VVVLTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLSAMVSMVTKDNPGVVTCLDEARHGFESGDFVSF SEVQGMVELNGNQPMEIKVLGPYTFSICDTSNFSDYIRGGIVSQVKVPKKISFKSLVASLAEPDFVVTDFAKFSRPAQLHIGFQALHQFC AQHGRPPRPRNEEDAAELVALAQAVNARALPAVQQNNLDEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFMPIMQWLYFDALE CLPEDKEVLTEDKCLQRQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIEKSNLNRQFLFR PWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERIYDDDFFQNLDGVANALDNVDARMYMDRRCVYYRKPLLESGTLGTKGNVQVV IPFLTESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDEFEGLFKQPAENVNQYLTDPKFVERTLRLAGTQPLEVLEAVQRSLVLQRP QTWADCVTWACHHWHTQYSNNIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPLTFDVNNPLHLDYVMAAANLFAQTYGLTGSQDRAAVATF -------------------------------------------------------------- >In-frame_ENST00000335972_ENST00000358951_ERR315385_UBA1_chrX_47071866_+_RAB3GAP2_chr1_220326669_length(transcript)=6108nt_BP=2692nt GGCTCGGCTGTAAGGAGGTGGCAGGGACAACCACAACCACAACGGCCGGGGGAGGAGAAGGCGGCAGCGGCGATTCTAGGCGGCCCAGGC GGCGGGGAGGAGGAGAAGGAGGAGGGTGGCGGCCGGGCTTGGCTTCGGCTCCTTGAGGAGTTGGCGGCGGCGCGACCCGGGGAACCGGCA TTGATGTCCAGCTCGCCGCTGTCCAAGAAACGTCGCGTGTCCGGGCCTGATCCAAAGCCGGGTTCTAACTGCTCCCCTGCCCAGTCCGTG TTGTCCGAAGTGCCCTCGGTGCCAACCAACGGAATGGCCAAGAACGGCAGTGAAGCAGACATAGACGAGGGCCTTTACTCCCGGCAGCTG TATGTGTTGGGCCATGAGGCAATGAAGCGGCTCCAGACATCCAGTGTCCTGGTATCAGGCCTGCGGGGCCTGGGCGTGGAGATCGCTAAG AACATCATCCTTGGTGGGGTCAAGGCTGTTACCCTACATGACCAGGGCACTGCCCAGTGGGCTGATCTTTCCTCCCAGTTCTACCTGCGG GAGGAGGACATCGGTAAAAACCGGGCCGAGGTATCACAGCCCCGCCTCGCTGAGCTCAACAGCTATGTGCCTGTCACTGCCTACACTGGA CCCCTCGTTGAGGACTTCCTTAGTGGTTTCCAGGTGGTGGTGCTCACCAACACCCCCCTGGAGGACCAGCTGCGAGTGGGTGAGTTCTGT CACAACCGTGGCATCAAGCTGGTGGTGGCAGACACGCGGGGCCTGTTTGGGCAGCTCTTCTGTGACTTTGGAGAGGAAATGATCCTCACA GATTCCAATGGGGAGCAGCCACTCAGTGCTATGGTTTCTATGGTTACCAAGGACAACCCCGGTGTGGTTACCTGCCTGGATGAGGCCCGA CACGGGTTTGAGAGCGGGGACTTTGTCTCCTTTTCAGAAGTACAGGGCATGGTTGAACTCAACGGAAATCAGCCCATGGAGATCAAAGTC CTGGGTCCTTATACCTTTAGCATCTGTGACACCTCCAACTTCTCCGACTACATCCGTGGAGGCATCGTCAGTCAGGTCAAAGTACCTAAG AAGATTAGCTTTAAATCCTTGGTGGCCTCACTGGCAGAACCTGACTTTGTGGTGACGGACTTCGCCAAGTTTTCTCGCCCTGCCCAGCTG CACATTGGCTTCCAGGCCCTGCACCAGTTCTGTGCTCAGCATGGCCGGCCACCTCGGCCCCGCAATGAGGAGGATGCAGCAGAACTGGTA GCCTTAGCACAGGCTGTGAATGCTCGAGCCCTGCCAGCAGTGCAGCAAAATAACCTGGACGAGGACCTCATCCGGAAGCTGGCATATGTG GCTGCTGGGGATCTGGCACCCATAAACGCCTTCATTGGGGGCCTGGCTGCCCAGGAAGTCATGAAGGCCTGCTCCGGGAAGTTCATGCCC ATCATGCAGTGGCTATACTTTGATGCCCTTGAGTGTCTCCCTGAGGACAAAGAGGTCCTCACAGAGGACAAGTGCCTCCAGCGCCAGAAC CGTTATGACGGGCAAGTGGCTGTGTTTGGCTCAGACCTGCAAGAGAAGCTGGGCAAGCAGAAGTATTTCCTGGTGGGTGCGGGGGCCATT GGCTGTGAGCTGCTCAAGAACTTTGCCATGATTGGGCTGGGCTGCGGGGAGGGTGGAGAAATCATCGTTACAGACATGGACACCATTGAG AAGTCAAATCTGAATCGACAGTTTCTTTTCCGGCCCTGGGATGTCACGAAGTTAAAGTCTGACACGGCTGCTGCAGCTGTGCGCCAAATG AATCCACATATCCGGGTGACAAGCCACCAGAACCGTGTGGGTCCTGACACGGAGCGCATCTATGATGACGATTTTTTCCAAAACCTAGAT GGCGTGGCCAATGCCCTGGACAACGTGGATGCCCGCATGTACATGGACCGCCGCTGTGTCTACTACCGGAAGCCACTGCTGGAGTCAGGC ACACTGGGCACCAAAGGCAATGTGCAGGTGGTGATCCCCTTCCTGACAGAGTCGTACAGTTCCAGCCAGGACCCACCTGAGAAGTCCATC CCCATCTGTACCCTGAAGAACTTCCCTAATGCCATCGAGCACACCCTGCAGTGGGCTCGGGATGAGTTTGAAGGCCTCTTCAAGCAGCCA GCAGAAAATGTCAACCAGTACCTCACAGACCCCAAGTTTGTGGAGCGAACACTGCGGCTGGCAGGCACTCAGCCCTTGGAGGTGCTGGAG GCTGTGCAGCGCAGCCTGGTGCTGCAGCGACCACAGACCTGGGCTGACTGCGTGACCTGGGCCTGCCACCACTGGCACACCCAGTACTCG AACAACATCCGGCAGCTGCTGCACAACTTCCCTCCTGACCAGCTCACAAGCTCAGGAGCGCCGTTCTGGTCTGGGCCCAAACGCTGTCCA CACCCGCTCACCTTTGATGTCAACAATCCCCTGCATCTGGACTATGTGATGGCTGCTGCCAACCTGTTTGCCCAGACCTACGGGCTGACA GGCTCTCAGGACCGAGCTGCTGTGGCCACATTCCTGCAGTCTGTGCAGGTCCCCGAATTCACCCCCAAGTCTGGCGTCAAGATCCATGTT TCTGACCAGGAGCTGCAGAGCGCCAATGCCTCTGTTGGACAAGCTCCCTGGATTCAAGATGTACCCCATTGACTTTGAGAAGGACCCCCA GGACCTTCAAAACACTGAAGTGCCAATTGCAACAACAGCTAAACTAGTAAATAAAGTAATTGAGCTTTTACCAGAAAAACATGGGCAATA TGGTCTAGCCTTACACCTCATTGAAGCTGTGGAAGCCATATCTCTTCCTTCTTTATGACACTTACCTACTGGAAATAGTCTAAAATTATG ATTATAACATGAAGTAGTGCATGGTTATTTTACATAGTAAGACCTGGAATTTTATGGGAAAAGTATGTCTTTTTTTTTCCTTTTGTAAAA TAAATAAAAGTATATACAACTTTTAAAAAGTGCAACCCTGGCTAAATTCCACTCCTTTGGTTAATACTGAAGATAAAATATAAACAAATG TCAACTCTGTTATAATTAATACAGATGTTTTACTGTTTATTTCTAATTCAAACACTTAAGTAGCTTTATTGTTAAACTTTGCTATTTAAA ATTGGTTATAATTTAGATTATGTTCTTATAAGATTCTATATTTCCTATCTAAAATGTTGTTGTAATTCAATTTAAATGTGTTCATGTACA GTCCCCATCAGTAGCGTATAGAACACCCCACTCTCCTTTAGTAAATGTTGAGAAAATGCCTTTGTTGTCATGCTCCAAATCCCACACTGG GCTGCCACCTGGGAGTTCTGGATACCGAAAGGTTCCTTTCCCAGAGGTTCTGCTGTTGCCATCAGAGGAGGATGACCGTGCTTGAGGAGG AAGAATGGGTTCAAGATCATCATATTCATCAGAAGGGGACACTAAATAGAACCCTTAACCTGTTGTACTTGCCAAAATTGAGAATCAGAG ATGTGTAAAATGCAGCAAATTAATTATAATGTAAGTTAAGATTTGCTTTTTGCCAAGTTGCAAAGTTGTATCCACATCAGGTCACTGTAA AAATGTATTATCTTGTAAAACTTATGTAAAAAAAAAAAAAAAAAAAAGGCAAAGATACTAAAAATTTTAAGTCCGACTTTATTTTTCCTA CAAGTGTTTAGAAATGCTTCTGGGATTTGCTAATATTATCTGTCCTTGGGAACAGTATTGAAAAAACTGCTTAGTGGTATTACAGCTTTA GCAAACCTACCTCACAGCTGGGATGAGAGGATAAAATACAACTAATTTTGTACCCTATAGTGCCTAGAGCAGTCCAAGTGCTAAATAAAT ATTTACTGATTAAAACCAAACTATAGCTACTCGGGAGGCTGGAGGAGGATCGCTTGAGCCCAGGAGTTTGAGGCCATTCTGGGCAATATA GCAAGACCCTGTCTCGAAAAAAAAAAAAAAAAGAAAAAACCAAACTAACCAAAACTCTGTAAAAGAGTGCTTTGAGCTCTACAAATACCA AGTATTTATTGTGGTATATTTTTAGAATGTAGCCATACAGTGTAATTATGGGTATCTGTCATGGATCACAATTATTATTCATAGTAAGTC ATTGTGATACAGAAGTTTGTTTCTTCACTTCCCCTTAAGAAGCCAACTATAGTAATCATGCAAAGTTGAGGAGTATGTCCTTCAGGGATA TAAAAAGAAAAACAAATCTGTTTTTTGAGCTAAAAGAGCACATCCAAACAAGAATTTAACTGGCTAAAATTTAGTAATTACTGTTAAGTA ACTATCAAACTTGAAATCTTACAAGATAAATGGTTAAGATGTCTTGAGTATTTGGGATGGGGGCCTGTGAGTCTGATTGAGACATACATT TTACAGAGTAGCAGCACTGGAAAGGGCTAGTCCAACCTCCCAGCCTCTGCTTGGGTCTCCGCTGCCCCAGCCACACACATCCTAGAATTC TTGTAAACATATCTGGCTCTGTGTTAACAGTCACTTGTTATATGTTTTCTAAGAGATTAGTTCTTCCTGTGATTTTTCCAAGTACGCTGA AAGTAGTAGTATGAACTTAAGGAGGCTAGTCAAAGAAACTTGGAGTTATAGGTATTTTTAAAGAATAAATCCTCAATTCCATCATCACTT GGCGGGGAGGGGGCACTTATTAAGCATTTTAGATAATAAAACTGGTTAAGCTTACTCTGGTAGAACAGACAATCAAATCTGGGGATTGCT GAGAACAATAATAAGCTGAAGTATGGCTCACAGAATCCTAACACAAATCATTAAGTCTCTAGTTAGATTTGTTATCCTAAAATTTTTCAT AGAATTTTAAAATCTAATTCTGACTTGTATGGTTAAGAAAAGCAGTTAAATATTTTACTACTTATCAAGGGCTTTTAAAATAAATAAATC TGATTGATAGGAAGAAAGGCAAATAAATACCTATGTAGACATTCTATAATAACAAAGAGCCATAGATGATAAAGGAATTAGATTTTAATG TAGAATGGGTGGTTTCTGAAACAAAGGTATGTGGTACTTTGTAGTTATTGATGAGAAGCCAGTAACCAGTAGTGTTTTCCTAGATATATG CCCACCCTCACACAACTTTCTTCATTAACAAACATTAAATATGCATTTGTATCTTATTAAATTATATTGTATAATGCTGAAGGAAAACAA AAAGTGTTCAAATAATCATAACTTCTACATTACAGGTTCTGTTTAGATGCAGAACTAGAGGGGCCAGGGTAAATGTAGATAAAGAGATAT ATAGCACCATGCTTCTTAATGCTTCATACTTTTGCAAACAGAAAAAAAAAGTTTTACTTTTATTATAAAACTTCATCTATGGTCAAAGTA AACACTGTTACATTTAAATTGCTTTTTAAAAACAATTGCGATCTAAAAAGTCAAAAATCTGAAATTTAATAATATGAGACTTACACTGAA TATAATGTTCATTTAGAAGTTGCTGTGGTCCACTTCATTTATAAGGAACAAATATTTTTACAGTACACTATAGCAACAGCAAAAGCCCTC TCTCACCCTGATAGGAATGGGTTTGCTGGGTGTCTAGAAGTTAGATTCCTGCTGAATAGAATTAGCCATCCTTAAAAGATTTTAATCCAA TACTGAACTGTTTATAAAATGCTTTCTCTATTGTAATGTACTGTAAGTAGTGAAATTCTGTATATACTGCTATTTTCTGTCTGTTCATTG TTGTGAACTTCTTATGTATATTAGTGAAATAAATTTTCAGCTTTCAGCCATTCTACAGGTTCATGACAAAGAGGTCCTTGCCTCTCAGCT GCTGGTGCTCACGGGGCAAAGGCTGGCTCATGCGCTTCTCCACACCCAGACAAAAGAAGGAATGGAGCTGCTTGCCAGACTTCCACCCAC ACTGTGTACTTGGCTGAAAGCAATGCACCCACTCCTTTTGGGAAAGACCAAGATTGGCCAGCTCTAGCTGTGGATTTAGCCCATCACCTT >In-frame_ENST00000335972_ENST00000358951_ERR315385_UBA1_chrX_47071866_+_RAB3GAP2_chr1_220326669_length(amino acids)=843AA_start in transcript=150_stop in transcript=2681 MAAARPGEPALMSSSPLSKKRRVSGPDPKPGSNCSPAQSVLSEVPSVPTNGMAKNGSEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSG LRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVEDFLSGFQVVVLTNTPL EDQLRVGEFCHNRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLSAMVSMVTKDNPGVVTCLDEARHGFESGDFVSFSEVQGMVEL NGNQPMEIKVLGPYTFSICDTSNFSDYIRGGIVSQVKVPKKISFKSLVASLAEPDFVVTDFAKFSRPAQLHIGFQALHQFCAQHGRPPRP RNEEDAAELVALAQAVNARALPAVQQNNLDEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFMPIMQWLYFDALECLPEDKEVL TEDKCLQRQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIEKSNLNRQFLFRPWDVTKLKS DTAAAAVRQMNPHIRVTSHQNRVGPDTERIYDDDFFQNLDGVANALDNVDARMYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTESYS SSQDPPEKSIPICTLKNFPNAIEHTLQWARDEFEGLFKQPAENVNQYLTDPKFVERTLRLAGTQPLEVLEAVQRSLVLQRPQTWADCVTW ACHHWHTQYSNNIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPLTFDVNNPLHLDYVMAAANLFAQTYGLTGSQDRAAVATFLQSVQVPEF -------------------------------------------------------------- >In-frame_ENST00000377269_ENST00000358951_ERR315385_UBA1_chrX_47071866_+_RAB3GAP2_chr1_220326669_length(transcript)=5048nt_BP=1632nt CTAATTGAAGTTTTTATTTTTTATGGAGGCATAACATATCTAGAATAAGGTACACAGATTTTTTTTTTTTTTTTTTTGAGGTGGAGTTTT GCTCATGTTGCCCAGGTTGGAGTGCAGTGGCGCAGTCTCGGCTCACTGCAGCCTCCGCCTCCCAGGTTCAAGCGATTCTCCTGCCTCAGC CTTCCAAAGTGCTGGGAATACAGGCGTGAGCCACCTCGCCTGGCACTCAGATCTTAATACATTTTTAGGCTGGGCATGGCGGCTGACACC TATAATCTCAGCACTCAGGAGGCCAAGGAGTGAGGTTTGTTTGAGCCCAGGAGTTCAAGACCAGCCTAGGCAACATAGCAAGACCCTGTC TCTACAACAAATCTTAAAAATTAGCCGGGTGTGGTGGCATGTGCCTGCTGTCCCAGCTATTCGGGAGGCTGAGGTGGGAGGATCGTTTCA ACCTGGGAGGTCAAGGCTGCTGTGAGCCGTGATTGCATCGCTGCACTCCAGCTCGGGTGACAGTGTGAGACTTTGTCTCAAACAACAAAA CAAAACAGTTTTCCACATACACAGCACTATTGTAACCACTGCCCAAATCAACTTCATTGATTTTTCTTTTTTTGAGACAGTCTTCCTCTG TCACCCAGGCTGGAGTGCAATGGCATGATCTCGGCTCACTGCAACCTCCGCCTCCCGGGTTCAAGAGATTTCCTGCCTCAGCCTCCTGAG TAGCTGGGATTACAGGCATCTGCCACCACGCCCAGCTACTTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGTCAGGCTGGTC TCGAACCCTTGACCTCAGGTGATCCATCTGCCTTAGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCTACTGTGCCTGGCCTGGTTTTT CAATTGAGGTGGGGGAATGGGGAAGGCTAGAGGGCTTCCCCACTTCCAGAGTAGCTGTGCGCCTTGTACTTGCTTTATTCACTGATGGTC CTTCTAATAATGCCTGCGGAAACCCATTTTGTCAACTGTGGCCACATGTAATCTGTTTGCTCTGTCTGCAGTGGGCTCGGGATGAGTTTG AAGGCCTCTTCAAGCAGCCAGCAGAAAATGTCAACCAGTACCTCACAGACCCCAAGTTTGTGGAGCGAACACTGCGGCTGGCAGGCACTC AGCCCTTGGAGGTGCTGGAGGCTGTGCAGCGCAGCCTGGTGCTGCAGCGACCACAGACCTGGGCTGACTGCGTGACCTGGGCCTGCCACC ACTGGCACACCCAGTACTCGAACAACATCCGGCAGCTGCTGCACAACTTCCCTCCTGACCAGCTCACAAGCTCAGGAGCGCCGTTCTGGT CTGGGCCCAAACGCTGTCCACACCCGCTCACCTTTGATGTCAACAATCCCCTGCATCTGGACTATGTGATGGCTGCTGCCAACCTGTTTG CCCAGACCTACGGGCTGACAGGCTCTCAGGACCGAGCTGCTGTGGCCACATTCCTGCAGTCTGTGCAGGTCCCCGAATTCACCCCCAAGT CTGGCGTCAAGATCCATGTTTCTGACCAGGAGCTGCAGAGCGCCAATGCCTCTGTTGGACAAGCTCCCTGGATTCAAGATGTACCCCATT GACTTTGAGAAGGACCCCCAGGACCTTCAAAACACTGAAGTGCCAATTGCAACAACAGCTAAACTAGTAAATAAAGTAATTGAGCTTTTA CCAGAAAAACATGGGCAATATGGTCTAGCCTTACACCTCATTGAAGCTGTGGAAGCCATATCTCTTCCTTCTTTATGACACTTACCTACT GGAAATAGTCTAAAATTATGATTATAACATGAAGTAGTGCATGGTTATTTTACATAGTAAGACCTGGAATTTTATGGGAAAAGTATGTCT TTTTTTTTCCTTTTGTAAAATAAATAAAAGTATATACAACTTTTAAAAAGTGCAACCCTGGCTAAATTCCACTCCTTTGGTTAATACTGA AGATAAAATATAAACAAATGTCAACTCTGTTATAATTAATACAGATGTTTTACTGTTTATTTCTAATTCAAACACTTAAGTAGCTTTATT GTTAAACTTTGCTATTTAAAATTGGTTATAATTTAGATTATGTTCTTATAAGATTCTATATTTCCTATCTAAAATGTTGTTGTAATTCAA TTTAAATGTGTTCATGTACAGTCCCCATCAGTAGCGTATAGAACACCCCACTCTCCTTTAGTAAATGTTGAGAAAATGCCTTTGTTGTCA TGCTCCAAATCCCACACTGGGCTGCCACCTGGGAGTTCTGGATACCGAAAGGTTCCTTTCCCAGAGGTTCTGCTGTTGCCATCAGAGGAG GATGACCGTGCTTGAGGAGGAAGAATGGGTTCAAGATCATCATATTCATCAGAAGGGGACACTAAATAGAACCCTTAACCTGTTGTACTT GCCAAAATTGAGAATCAGAGATGTGTAAAATGCAGCAAATTAATTATAATGTAAGTTAAGATTTGCTTTTTGCCAAGTTGCAAAGTTGTA TCCACATCAGGTCACTGTAAAAATGTATTATCTTGTAAAACTTATGTAAAAAAAAAAAAAAAAAAAAGGCAAAGATACTAAAAATTTTAA GTCCGACTTTATTTTTCCTACAAGTGTTTAGAAATGCTTCTGGGATTTGCTAATATTATCTGTCCTTGGGAACAGTATTGAAAAAACTGC TTAGTGGTATTACAGCTTTAGCAAACCTACCTCACAGCTGGGATGAGAGGATAAAATACAACTAATTTTGTACCCTATAGTGCCTAGAGC AGTCCAAGTGCTAAATAAATATTTACTGATTAAAACCAAACTATAGCTACTCGGGAGGCTGGAGGAGGATCGCTTGAGCCCAGGAGTTTG AGGCCATTCTGGGCAATATAGCAAGACCCTGTCTCGAAAAAAAAAAAAAAAAGAAAAAACCAAACTAACCAAAACTCTGTAAAAGAGTGC TTTGAGCTCTACAAATACCAAGTATTTATTGTGGTATATTTTTAGAATGTAGCCATACAGTGTAATTATGGGTATCTGTCATGGATCACA ATTATTATTCATAGTAAGTCATTGTGATACAGAAGTTTGTTTCTTCACTTCCCCTTAAGAAGCCAACTATAGTAATCATGCAAAGTTGAG GAGTATGTCCTTCAGGGATATAAAAAGAAAAACAAATCTGTTTTTTGAGCTAAAAGAGCACATCCAAACAAGAATTTAACTGGCTAAAAT TTAGTAATTACTGTTAAGTAACTATCAAACTTGAAATCTTACAAGATAAATGGTTAAGATGTCTTGAGTATTTGGGATGGGGGCCTGTGA GTCTGATTGAGACATACATTTTACAGAGTAGCAGCACTGGAAAGGGCTAGTCCAACCTCCCAGCCTCTGCTTGGGTCTCCGCTGCCCCAG CCACACACATCCTAGAATTCTTGTAAACATATCTGGCTCTGTGTTAACAGTCACTTGTTATATGTTTTCTAAGAGATTAGTTCTTCCTGT GATTTTTCCAAGTACGCTGAAAGTAGTAGTATGAACTTAAGGAGGCTAGTCAAAGAAACTTGGAGTTATAGGTATTTTTAAAGAATAAAT CCTCAATTCCATCATCACTTGGCGGGGAGGGGGCACTTATTAAGCATTTTAGATAATAAAACTGGTTAAGCTTACTCTGGTAGAACAGAC AATCAAATCTGGGGATTGCTGAGAACAATAATAAGCTGAAGTATGGCTCACAGAATCCTAACACAAATCATTAAGTCTCTAGTTAGATTT GTTATCCTAAAATTTTTCATAGAATTTTAAAATCTAATTCTGACTTGTATGGTTAAGAAAAGCAGTTAAATATTTTACTACTTATCAAGG GCTTTTAAAATAAATAAATCTGATTGATAGGAAGAAAGGCAAATAAATACCTATGTAGACATTCTATAATAACAAAGAGCCATAGATGAT AAAGGAATTAGATTTTAATGTAGAATGGGTGGTTTCTGAAACAAAGGTATGTGGTACTTTGTAGTTATTGATGAGAAGCCAGTAACCAGT AGTGTTTTCCTAGATATATGCCCACCCTCACACAACTTTCTTCATTAACAAACATTAAATATGCATTTGTATCTTATTAAATTATATTGT ATAATGCTGAAGGAAAACAAAAAGTGTTCAAATAATCATAACTTCTACATTACAGGTTCTGTTTAGATGCAGAACTAGAGGGGCCAGGGT AAATGTAGATAAAGAGATATATAGCACCATGCTTCTTAATGCTTCATACTTTTGCAAACAGAAAAAAAAAGTTTTACTTTTATTATAAAA CTTCATCTATGGTCAAAGTAAACACTGTTACATTTAAATTGCTTTTTAAAAACAATTGCGATCTAAAAAGTCAAAAATCTGAAATTTAAT AATATGAGACTTACACTGAATATAATGTTCATTTAGAAGTTGCTGTGGTCCACTTCATTTATAAGGAACAAATATTTTTACAGTACACTA TAGCAACAGCAAAAGCCCTCTCTCACCCTGATAGGAATGGGTTTGCTGGGTGTCTAGAAGTTAGATTCCTGCTGAATAGAATTAGCCATC CTTAAAAGATTTTAATCCAATACTGAACTGTTTATAAAATGCTTTCTCTATTGTAATGTACTGTAAGTAGTGAAATTCTGTATATACTGC TATTTTCTGTCTGTTCATTGTTGTGAACTTCTTATGTATATTAGTGAAATAAATTTTCAGCTTTCAGCCATTCTACAGGTTCATGACAAA GAGGTCCTTGCCTCTCAGCTGCTGGTGCTCACGGGGCAAAGGCTGGCTCATGCGCTTCTCCACACCCAGACAAAAGAAGGAATGGAGCTG CTTGCCAGACTTCCACCCACACTGTGTACTTGGCTGAAAGCAATGCACCCACTCCTTTTGGGAAAGACCAAGATTGGCCAGCTCTAGCTG TGGATTTAGCCCATCACCTTCAAGTTAGTGAAGATGTTGTTAGAAGGCATTATGTGGGGGAACTATACAACTATGGAGTTGACCACTTAG >In-frame_ENST00000377269_ENST00000358951_ERR315385_UBA1_chrX_47071866_+_RAB3GAP2_chr1_220326669_length(amino acids)=280AA_start in transcript=779_stop in transcript=1621 MGFHHVGQAGLEPLTSGDPSALASQSAGITGVSYCAWPGFSIEVGEWGRLEGFPTSRVAVRLVLALFTDGPSNNACGNPFCQLWPHVICL LCLQWARDEFEGLFKQPAENVNQYLTDPKFVERTLRLAGTQPLEVLEAVQRSLVLQRPQTWADCVTWACHHWHTQYSNNIRQLLHNFPPD QLTSSGAPFWSGPKRCPHPLTFDVNNPLHLDYVMAAANLFAQTYGLTGSQDRAAVATFLQSVQVPEFTPKSGVKIHVSDQELQSANASVG -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for UBA1-RAB3GAP2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for UBA1-RAB3GAP2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for UBA1-RAB3GAP2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | UBA1 | C1844934 | Arthrogryposis multiplex congenita, distal, X-linked | 2 | CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT |
| Hgene | UBA1 | C0007137 | Squamous cell carcinoma | 1 | CTD_human |
| Tgene | RAB3GAP2 | C3280214 | WARBURG MICRO SYNDROME 2 | 4 | GENOMICS_ENGLAND |
| Tgene | RAB3GAP2 | C0796037 | Martsolf syndrome | 3 | CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT |
| Tgene | RAB3GAP2 | C0037772 | Spastic Paraplegia | 1 | GENOMICS_ENGLAND |
| Tgene | RAB3GAP2 | C1838625 | Warburg Sjo Fledelius syndrome | 1 | CTD_human;GENOMICS_ENGLAND;ORPHANET |
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