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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:UBE2D3-MANBA (FusionGDB2 ID:95372)

Fusion Gene Summary for UBE2D3-MANBA

check button Fusion gene summary
Fusion gene informationFusion gene name: UBE2D3-MANBA
Fusion gene ID: 95372
HgeneTgene
Gene symbol

UBE2D3

MANBA

Gene ID

7323

4126

Gene nameubiquitin conjugating enzyme E2 D3mannosidase beta
SynonymsE2(17)KB3|UBC4/5|UBCH5CMANB1
Cytomap

4q24

4q24

Type of geneprotein-codingprotein-coding
Descriptionubiquitin-conjugating enzyme E2 D3(E3-independent) E2 ubiquitin-conjugating enzyme D3E2 ubiquitin-conjugating enzyme D3ubiquitin carrier protein D3ubiquitin conjugating enzyme E2D 3ubiquitin-conjugating enzyme E2(17)KB 3ubiquitin-conjugating enzyme beta-mannosidasebeta-mannosidase Alysosomal beta A mannosidasemannanasemannasemannosidase, beta A, lysosomal
Modification date2020031320200313
UniProtAcc.

Q9NQG1

Ensembl transtripts involved in fusion geneENST00000453744, ENST00000394801, 
ENST00000394803, ENST00000394804, 
ENST00000343106, ENST00000321805, 
ENST00000350435, ENST00000338145, 
ENST00000349311, ENST00000504211, 
ENST00000357194, ENST00000505207, 
ENST00000507845, ENST00000502404, 
ENST00000513098, 		ENST00000226578, 
ENST00000505239, 
Fusion gene scores* DoF score12 X 14 X 7=11767 X 6 X 7=294
# samples 177
** MAII scorelog2(17/1176*10)=-2.79028140869866
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/294*10)=-2.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: UBE2D3 [Title/Abstract] AND MANBA [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMANBA(103571694)-UBE2D3(103723795), # samples:1
MANBA(103681875)-UBE2D3(103731012), # samples:1
UBE2D3(103722611)-MANBA(103611928), # samples:1
Anticipated loss of major functional domain due to fusion event.UBE2D3-MANBA seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
UBE2D3-MANBA seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneUBE2D3

GO:0000209

protein polyubiquitination

14765125|16522193

HgeneUBE2D3

GO:0006513

protein monoubiquitination

20347421

HgeneUBE2D3

GO:0016567

protein ubiquitination

9990509|21532592

HgeneUBE2D3

GO:0043161

proteasome-mediated ubiquitin-dependent protein catabolic process

20347421

HgeneUBE2D3

GO:0051865

protein autoubiquitination

21068390

HgeneUBE2D3

GO:0070936

protein K48-linked ubiquitination

20061386

HgeneUBE2D3

GO:0070979

protein K11-linked ubiquitination

20061386


check buttonFusion gene breakpoints across UBE2D3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across MANBA (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-25-1632-01AUBE2D3chr4

103722611

-MANBAchr4

103611928

-


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Fusion Gene ORF analysis for UBE2D3-MANBA

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000453744ENST00000226578UBE2D3chr4

103722611

-MANBAchr4

103611928

-
Frame-shiftENST00000453744ENST00000505239UBE2D3chr4

103722611

-MANBAchr4

103611928

-
Frame-shiftENST00000394801ENST00000226578UBE2D3chr4

103722611

-MANBAchr4

103611928

-
Frame-shiftENST00000394801ENST00000505239UBE2D3chr4

103722611

-MANBAchr4

103611928

-
Frame-shiftENST00000394803ENST00000226578UBE2D3chr4

103722611

-MANBAchr4

103611928

-
Frame-shiftENST00000394803ENST00000505239UBE2D3chr4

103722611

-MANBAchr4

103611928

-
In-frameENST00000394804ENST00000226578UBE2D3chr4

103722611

-MANBAchr4

103611928

-
In-frameENST00000394804ENST00000505239UBE2D3chr4

103722611

-MANBAchr4

103611928

-
Frame-shiftENST00000343106ENST00000226578UBE2D3chr4

103722611

-MANBAchr4

103611928

-
Frame-shiftENST00000343106ENST00000505239UBE2D3chr4

103722611

-MANBAchr4

103611928

-
In-frameENST00000321805ENST00000226578UBE2D3chr4

103722611

-MANBAchr4

103611928

-
In-frameENST00000321805ENST00000505239UBE2D3chr4

103722611

-MANBAchr4

103611928

-
In-frameENST00000350435ENST00000226578UBE2D3chr4

103722611

-MANBAchr4

103611928

-
In-frameENST00000350435ENST00000505239UBE2D3chr4

103722611

-MANBAchr4

103611928

-
In-frameENST00000338145ENST00000226578UBE2D3chr4

103722611

-MANBAchr4

103611928

-
In-frameENST00000338145ENST00000505239UBE2D3chr4

103722611

-MANBAchr4

103611928

-
In-frameENST00000349311ENST00000226578UBE2D3chr4

103722611

-MANBAchr4

103611928

-
In-frameENST00000349311ENST00000505239UBE2D3chr4

103722611

-MANBAchr4

103611928

-
Frame-shiftENST00000504211ENST00000226578UBE2D3chr4

103722611

-MANBAchr4

103611928

-
Frame-shiftENST00000504211ENST00000505239UBE2D3chr4

103722611

-MANBAchr4

103611928

-
In-frameENST00000357194ENST00000226578UBE2D3chr4

103722611

-MANBAchr4

103611928

-
In-frameENST00000357194ENST00000505239UBE2D3chr4

103722611

-MANBAchr4

103611928

-
Frame-shiftENST00000505207ENST00000226578UBE2D3chr4

103722611

-MANBAchr4

103611928

-
Frame-shiftENST00000505207ENST00000505239UBE2D3chr4

103722611

-MANBAchr4

103611928

-
Frame-shiftENST00000507845ENST00000226578UBE2D3chr4

103722611

-MANBAchr4

103611928

-
Frame-shiftENST00000507845ENST00000505239UBE2D3chr4

103722611

-MANBAchr4

103611928

-
Frame-shiftENST00000502404ENST00000226578UBE2D3chr4

103722611

-MANBAchr4

103611928

-
Frame-shiftENST00000502404ENST00000505239UBE2D3chr4

103722611

-MANBAchr4

103611928

-
intron-3CDSENST00000513098ENST00000226578UBE2D3chr4

103722611

-MANBAchr4

103611928

-
intron-3CDSENST00000513098ENST00000505239UBE2D3chr4

103722611

-MANBAchr4

103611928

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000394804UBE2D3chr4103722611-ENST00000226578MANBAchr4103611928-31289976932963756
ENST00000394804UBE2D3chr4103722611-ENST00000505239MANBAchr4103611928-30339976932963756
ENST00000321805UBE2D3chr4103722611-ENST00000226578MANBAchr4103611928-28987674632733756
ENST00000321805UBE2D3chr4103722611-ENST00000505239MANBAchr4103611928-28037674632733756
ENST00000350435UBE2D3chr4103722611-ENST00000226578MANBAchr4103611928-2534403842369761
ENST00000350435UBE2D3chr4103722611-ENST00000505239MANBAchr4103611928-2439403842369761
ENST00000338145UBE2D3chr4103722611-ENST00000226578MANBAchr4103611928-27245932892559756
ENST00000338145UBE2D3chr4103722611-ENST00000505239MANBAchr4103611928-26295932892559756
ENST00000349311UBE2D3chr4103722611-ENST00000226578MANBAchr4103611928-26785472432513756
ENST00000349311UBE2D3chr4103722611-ENST00000505239MANBAchr4103611928-25835472432513756
ENST00000357194UBE2D3chr4103722611-ENST00000226578MANBAchr4103611928-25934621522428758
ENST00000357194UBE2D3chr4103722611-ENST00000505239MANBAchr4103611928-24984621522428758

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000394804ENST00000226578UBE2D3chr4103722611-MANBAchr4103611928-0.0008455340.99915445
ENST00000394804ENST00000505239UBE2D3chr4103722611-MANBAchr4103611928-0.0007921470.9992079
ENST00000321805ENST00000226578UBE2D3chr4103722611-MANBAchr4103611928-0.0010616690.9989384
ENST00000321805ENST00000505239UBE2D3chr4103722611-MANBAchr4103611928-0.0009746870.99902534
ENST00000350435ENST00000226578UBE2D3chr4103722611-MANBAchr4103611928-0.0013371190.9986628
ENST00000350435ENST00000505239UBE2D3chr4103722611-MANBAchr4103611928-0.0012018980.99879813
ENST00000338145ENST00000226578UBE2D3chr4103722611-MANBAchr4103611928-0.0009756150.9990244
ENST00000338145ENST00000505239UBE2D3chr4103722611-MANBAchr4103611928-0.0008779320.9991221
ENST00000349311ENST00000226578UBE2D3chr4103722611-MANBAchr4103611928-0.0010780370.998922
ENST00000349311ENST00000505239UBE2D3chr4103722611-MANBAchr4103611928-0.0009661850.9990338
ENST00000357194ENST00000226578UBE2D3chr4103722611-MANBAchr4103611928-0.0026579340.99734205
ENST00000357194ENST00000505239UBE2D3chr4103722611-MANBAchr4103611928-0.0024551770.9975448

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Fusion Genomic Features for UBE2D3-MANBA


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for UBE2D3-MANBA


check button Go to

FGviewer for the breakpoints of chr4:103722611-chr4:103611928

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.MANBA

Q9NQG1

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneUBE2D3chr4:103722611chr4:103611928ENST00000321805-681_147101.33333333333333148.0DomainUBC core
HgeneUBE2D3chr4:103722611chr4:103611928ENST00000338145-681_147101.33333333333333148.0DomainUBC core
HgeneUBE2D3chr4:103722611chr4:103611928ENST00000343106-581_147101.33333333333333374.0DomainUBC core
HgeneUBE2D3chr4:103722611chr4:103611928ENST00000349311-681_147101.33333333333333148.0DomainUBC core
HgeneUBE2D3chr4:103722611chr4:103611928ENST00000357194-571_147103.33333333333333150.0DomainUBC core
HgeneUBE2D3chr4:103722611chr4:103611928ENST00000394801-681_147101.33333333333333148.0DomainUBC core
HgeneUBE2D3chr4:103722611chr4:103611928ENST00000394803-681_147101.33333333333333148.0DomainUBC core
HgeneUBE2D3chr4:103722611chr4:103611928ENST00000394804-681_147101.33333333333333148.0DomainUBC core
HgeneUBE2D3chr4:103722611chr4:103611928ENST00000453744-681_147101.33333333333333148.0DomainUBC core
TgeneMANBAchr4:103722611chr4:103611928ENST00000226578417190_192224.33333333333334880.0RegionSubstrate binding


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Fusion Gene Sequence for UBE2D3-MANBA


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000394804_ENST00000226578_TCGA-25-1632-01A_UBE2D3_chr4_103722611_-_MANBA_chr4_103611928_length(transcript)=3128nt_BP=997nt
ACCAAGTGAGGAAACTGGGGGACGCTGTGGGGAGGGGCGTGGGGCTGGATCGCGCAGCGGCTGCTTCCTTTACCTTCCTCCCATGGTCTC
CTTCCGGTTCTCGATGCTTCTCTGAGCCTAAGGGTTTCCGCCACTCGTTCACCCTCCCCCCAGCTCATGATCCTCCTCCCTCCCCCGCCC
TCCTGGTCCAATCTCCGATCTGTTTAGTAAGAAGGTGCTGTTCCGAGAAGAAGGAAAAGGGCTTGACACGTATTCACTCGGCCCCGGACG
TGGGAAGCAAGCCGTCTGGCTTCGGCCTCACATCGGTCTTGTGCTCGGGACGGCGGCGTTGGCGGACTGATCCGCGGCGGTGAAGAGAGG
CCGGGAAGTTAAACTTGTAGCCACCACCTCCGCTCTTCCCGTCACCCTCGCCCCCACTTCGGGCCGAAAGCACGGTACAGAGGCTGTTGG
TGGCTTTGCCACGCCACCCCACCCACCCCGGATCGCGGCTGTCTTAAGGGACCTGGATTCATCAGGGGCTCTTCGGGGCCTGTGCGAGTG
CTGATCTGCTCCGTTTTTGCAAAAGGCGCCTGTGTCTGGCAGAGCTGGTGTGAGACGAGACAATCCTGCCCCGCCGCCGGGATAATCAAG
AGTTTTGGCCGGACCTTTGAGCATACACCGAGAGAGTGAGGAGCCAGACGACAAGCACACACTATGGCGCTGAAACGGATTAATAAGGAA
CTTAGTGATTTGGCCCGTGACCCTCCAGCACAATGTTCTGCAGGTCCAGTTGGGGATGATATGTTTCATTGGCAAGCCACAATTATGGGA
CCTAATGACAGCCCATATCAAGGCGGTGTATTCTTTTTGACAATTCATTTTCCTACAGACTACCCCTTCAAACCACCTAAGGTTGCATTT
ACAACAAGAATTTATCATCCAAATATTAACAGTAATGGCAGCATTTGTCTCGATATTCTAAGATCACAGTGGTCGCCTGCTTTAACAATT
TCTAAAGATAAGAGTGCCCAGGAGTGGAATCTGGAAATAGAGTCTACATTTGATGTTGTCAGCTCAAAGCCAGTTGGTGGTCAAGTGATC
GTAGCCATCCCTAAGTTGCAAACACAACAGACATACAGCATTGAACTTCAACCTGGGAAAAGGATTGTTGAGCTATTTGTGAACATTAGC
AAGAATATTACTGTAGAAACTTGGTGGCCTCATGGACATGGAAACCAGACTGGGTACAACATGACTGTTCTTTTTGAACTGGATGGAGGC
TTAAATATTGAAAAATCAGCTAAGGTTTATTTTAGGACAGTGGAACTTATAGAAGAGCCTATAAAAGGGTCTCCTGGTTTGAGTTTCTAT
TTCAAAATTAATGGATTTCCCATATTTCTAAAAGGCTCAAACTGGATCCCAGCAGATTCATTCCAGGACCGAGTAACCTCTGAGTTGTTA
CGGCTCCTTTTACAGTCTGTTGTGGATGCTAATATGAATACTCTTCGGGTTTGGGGAGGAGGAATTTATGAGCAGGATGAATTCTATGAA
CTCTGTGATGAACTAGGAATAATGGTATGGCAGGATTTTATGTTTGCCTGTGCCCTTTATCCAACTGATCAGGGCTTCCTGGATTCAGTG
ACAGCAGAAGTTGCCTACCAGATCAAGAGACTGAAATCTCATCCTTCTATCATCATATGGAGTGGCAATAATGAAAATGAGGAGGCGCTG
ATGATGAATTGGTATCATATCAGTTTCACTGACCGGCCAATCTACATCAAGGACTATGTGACACTCTATGTGAAAAACATCAGAGAGCTC
GTACTGGCAGGAGACAAGAGTCGTCCTTTTATTACGTCCAGTCCTACAAATGGGGCTGAAACTGTTGCAGAAGCCTGGGTCTCTCAAAAC
CCTAATAGCAATTATTTTGGTGATGTACATTTTTATGACTATATCAGTGATTGCTGGAACTGGAAAGTTTTCCCAAAAGCTCGATTTGCA
TCTGAATATGGATATCAGTCCTGGCCGTCCTTCAGTACATTAGAAAAGGTCTCGTCTACAGAGGACTGGTCTTTCAATAGCAAGTTTTCA
CTTCATCGACAACATCACGAAGGTGGTAACAAACAAATGCTTTATCAGGCTGGACTTCATTTCAAACTCCCCCAAAGCACAGATCCATTA
CGCACATTTAAAGATACCATCTACCTTACTCAGGTGATGCAGGCCCAGTGTGTCAAAACAGAAACTGAATTCTACCGCCGTAGTCGCAGC
GAGATAGTGGATCAGCAAGGGCACACGATGGGGGCACTTTATTGGCAGTTGAATGACATCTGGCAAGCTCCTTCCTGGGCTTCTCTTGAG
TACGGAGGAAAGTGGAAAATGCTTCATTACTTTGCTCAGAATTTCTTTGCTCCACTGTTGCCAGTAGGCTTTGAGAATGAAAACACGTTC
TATATCTATGGTGTGTCAGATCTTCACTCGGATTATTCGATGACACTCAGTGTGAGAGTCCATACATGGAGCTCCCTGGAGCCCGTGTGC
TCTCGTGTGACTGAACGTTTTGTGATGAAAGGAGGAGAGGCTGTCTGCCTTTATGAGGAGCCAGTGTCTGAATTGCTGAGGAGATGTGGG
AATTGCACACGGGAAAGCTGTGTGGTTTCCTTTTACCTTTCAGCTGACCATGAACTCCTGAGCCCGACCAACTACCACTTCTTGTCCTCA
CCGAAGGAGGCCGTGGGGCTCTGCAAGGCGCAGATCACTGCCATCATCTCTCAGCAAGGTGACATATTTGTTTTTGACCTGGAGACCTCA
GCTGTCGCTCCCTTTGTTTGGTTGGATGTAGGAAGCATCCCAGGGAGATTTAGTGACAATGGTTTCCTCATGACTGAGAAGACACGAACT
ATATTATTTTACCCTTGGGAGCCCACCAGCAAGAATGAGTTGGAGCAATCTTTTCATGTGACCTCCTTAACAGATATTTACTGAAGGAAT
CTAGGTTGTATTTTCAGTGGACAATGGGAATAAAGCATTTCTAAAGCACCGACTGGAGAGGAAGGCAACAGAGACAAGGAGAGAAGCCGA

>In-frame_ENST00000394804_ENST00000226578_TCGA-25-1632-01A_UBE2D3_chr4_103722611_-_MANBA_chr4_103611928_length(amino acids)=756AA_start in transcript=693_stop in transcript=2963
MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR
SQWSPALTISKDKSAQEWNLEIESTFDVVSSKPVGGQVIVAIPKLQTQQTYSIELQPGKRIVELFVNISKNITVETWWPHGHGNQTGYNM
TVLFELDGGLNIEKSAKVYFRTVELIEEPIKGSPGLSFYFKINGFPIFLKGSNWIPADSFQDRVTSELLRLLLQSVVDANMNTLRVWGGG
IYEQDEFYELCDELGIMVWQDFMFACALYPTDQGFLDSVTAEVAYQIKRLKSHPSIIIWSGNNENEEALMMNWYHISFTDRPIYIKDYVT
LYVKNIRELVLAGDKSRPFITSSPTNGAETVAEAWVSQNPNSNYFGDVHFYDYISDCWNWKVFPKARFASEYGYQSWPSFSTLEKVSSTE
DWSFNSKFSLHRQHHEGGNKQMLYQAGLHFKLPQSTDPLRTFKDTIYLTQVMQAQCVKTETEFYRRSRSEIVDQQGHTMGALYWQLNDIW
QAPSWASLEYGGKWKMLHYFAQNFFAPLLPVGFENENTFYIYGVSDLHSDYSMTLSVRVHTWSSLEPVCSRVTERFVMKGGEAVCLYEEP
VSELLRRCGNCTRESCVVSFYLSADHELLSPTNYHFLSSPKEAVGLCKAQITAIISQQGDIFVFDLETSAVAPFVWLDVGSIPGRFSDNG

--------------------------------------------------------------
>In-frame_ENST00000394804_ENST00000505239_TCGA-25-1632-01A_UBE2D3_chr4_103722611_-_MANBA_chr4_103611928_length(transcript)=3033nt_BP=997nt
ACCAAGTGAGGAAACTGGGGGACGCTGTGGGGAGGGGCGTGGGGCTGGATCGCGCAGCGGCTGCTTCCTTTACCTTCCTCCCATGGTCTC
CTTCCGGTTCTCGATGCTTCTCTGAGCCTAAGGGTTTCCGCCACTCGTTCACCCTCCCCCCAGCTCATGATCCTCCTCCCTCCCCCGCCC
TCCTGGTCCAATCTCCGATCTGTTTAGTAAGAAGGTGCTGTTCCGAGAAGAAGGAAAAGGGCTTGACACGTATTCACTCGGCCCCGGACG
TGGGAAGCAAGCCGTCTGGCTTCGGCCTCACATCGGTCTTGTGCTCGGGACGGCGGCGTTGGCGGACTGATCCGCGGCGGTGAAGAGAGG
CCGGGAAGTTAAACTTGTAGCCACCACCTCCGCTCTTCCCGTCACCCTCGCCCCCACTTCGGGCCGAAAGCACGGTACAGAGGCTGTTGG
TGGCTTTGCCACGCCACCCCACCCACCCCGGATCGCGGCTGTCTTAAGGGACCTGGATTCATCAGGGGCTCTTCGGGGCCTGTGCGAGTG
CTGATCTGCTCCGTTTTTGCAAAAGGCGCCTGTGTCTGGCAGAGCTGGTGTGAGACGAGACAATCCTGCCCCGCCGCCGGGATAATCAAG
AGTTTTGGCCGGACCTTTGAGCATACACCGAGAGAGTGAGGAGCCAGACGACAAGCACACACTATGGCGCTGAAACGGATTAATAAGGAA
CTTAGTGATTTGGCCCGTGACCCTCCAGCACAATGTTCTGCAGGTCCAGTTGGGGATGATATGTTTCATTGGCAAGCCACAATTATGGGA
CCTAATGACAGCCCATATCAAGGCGGTGTATTCTTTTTGACAATTCATTTTCCTACAGACTACCCCTTCAAACCACCTAAGGTTGCATTT
ACAACAAGAATTTATCATCCAAATATTAACAGTAATGGCAGCATTTGTCTCGATATTCTAAGATCACAGTGGTCGCCTGCTTTAACAATT
TCTAAAGATAAGAGTGCCCAGGAGTGGAATCTGGAAATAGAGTCTACATTTGATGTTGTCAGCTCAAAGCCAGTTGGTGGTCAAGTGATC
GTAGCCATCCCTAAGTTGCAAACACAACAGACATACAGCATTGAACTTCAACCTGGGAAAAGGATTGTTGAGCTATTTGTGAACATTAGC
AAGAATATTACTGTAGAAACTTGGTGGCCTCATGGACATGGAAACCAGACTGGGTACAACATGACTGTTCTTTTTGAACTGGATGGAGGC
TTAAATATTGAAAAATCAGCTAAGGTTTATTTTAGGACAGTGGAACTTATAGAAGAGCCTATAAAAGGGTCTCCTGGTTTGAGTTTCTAT
TTCAAAATTAATGGATTTCCCATATTTCTAAAAGGCTCAAACTGGATCCCAGCAGATTCATTCCAGGACCGAGTAACCTCTGAGTTGTTA
CGGCTCCTTTTACAGTCTGTTGTGGATGCTAATATGAATACTCTTCGGGTTTGGGGAGGAGGAATTTATGAGCAGGATGAATTCTATGAA
CTCTGTGATGAACTAGGAATAATGGTATGGCAGGATTTTATGTTTGCCTGTGCCCTTTATCCAACTGATCAGGGCTTCCTGGATTCAGTG
ACAGCAGAAGTTGCCTACCAGATCAAGAGACTGAAATCTCATCCTTCTATCATCATATGGAGTGGCAATAATGAAAATGAGGAGGCGCTG
ATGATGAATTGGTATCATATCAGTTTCACTGACCGGCCAATCTACATCAAGGACTATGTGACACTCTATGTGAAAAACATCAGAGAGCTC
GTACTGGCAGGAGACAAGAGTCGTCCTTTTATTACGTCCAGTCCTACAAATGGGGCTGAAACTGTTGCAGAAGCCTGGGTCTCTCAAAAC
CCTAATAGCAATTATTTTGGTGATGTACATTTTTATGACTATATCAGTGATTGCTGGAACTGGAAAGTTTTCCCAAAAGCTCGATTTGCA
TCTGAATATGGATATCAGTCCTGGCCGTCCTTCAGTACATTAGAAAAGGTCTCGTCTACAGAGGACTGGTCTTTCAATAGCAAGTTTTCA
CTTCATCGACAACATCACGAAGGTGGTAACAAACAAATGCTTTATCAGGCTGGACTTCATTTCAAACTCCCCCAAAGCACAGATCCATTA
CGCACATTTAAAGATACCATCTACCTTACTCAGGTGATGCAGGCCCAGTGTGTCAAAACAGAAACTGAATTCTACCGCCGTAGTCGCAGC
GAGATAGTGGATCAGCAAGGGCACACGATGGGGGCACTTTATTGGCAGTTGAATGACATCTGGCAAGCTCCTTCCTGGGCTTCTCTTGAG
TACGGAGGAAAGTGGAAAATGCTTCATTACTTTGCTCAGAATTTCTTTGCTCCACTGTTGCCAGTAGGCTTTGAGAATGAAAACACGTTC
TATATCTATGGTGTGTCAGATCTTCACTCGGATTATTCGATGACACTCAGTGTGAGAGTCCATACATGGAGCTCCCTGGAGCCCGTGTGC
TCTCGTGTGACTGAACGTTTTGTGATGAAAGGAGGAGAGGCTGTCTGCCTTTATGAGGAGCCAGTGTCTGAATTGCTGAGGAGATGTGGG
AATTGCACACGGGAAAGCTGTGTGGTTTCCTTTTACCTTTCAGCTGACCATGAACTCCTGAGCCCGACCAACTACCACTTCTTGTCCTCA
CCGAAGGAGGCCGTGGGGCTCTGCAAGGCGCAGATCACTGCCATCATCTCTCAGCAAGGTGACATATTTGTTTTTGACCTGGAGACCTCA
GCTGTCGCTCCCTTTGTTTGGTTGGATGTAGGAAGCATCCCAGGGAGATTTAGTGACAATGGTTTCCTCATGACTGAGAAGACACGAACT
ATATTATTTTACCCTTGGGAGCCCACCAGCAAGAATGAGTTGGAGCAATCTTTTCATGTGACCTCCTTAACAGATATTTACTGAAGGAAT

>In-frame_ENST00000394804_ENST00000505239_TCGA-25-1632-01A_UBE2D3_chr4_103722611_-_MANBA_chr4_103611928_length(amino acids)=756AA_start in transcript=693_stop in transcript=2963
MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR
SQWSPALTISKDKSAQEWNLEIESTFDVVSSKPVGGQVIVAIPKLQTQQTYSIELQPGKRIVELFVNISKNITVETWWPHGHGNQTGYNM
TVLFELDGGLNIEKSAKVYFRTVELIEEPIKGSPGLSFYFKINGFPIFLKGSNWIPADSFQDRVTSELLRLLLQSVVDANMNTLRVWGGG
IYEQDEFYELCDELGIMVWQDFMFACALYPTDQGFLDSVTAEVAYQIKRLKSHPSIIIWSGNNENEEALMMNWYHISFTDRPIYIKDYVT
LYVKNIRELVLAGDKSRPFITSSPTNGAETVAEAWVSQNPNSNYFGDVHFYDYISDCWNWKVFPKARFASEYGYQSWPSFSTLEKVSSTE
DWSFNSKFSLHRQHHEGGNKQMLYQAGLHFKLPQSTDPLRTFKDTIYLTQVMQAQCVKTETEFYRRSRSEIVDQQGHTMGALYWQLNDIW
QAPSWASLEYGGKWKMLHYFAQNFFAPLLPVGFENENTFYIYGVSDLHSDYSMTLSVRVHTWSSLEPVCSRVTERFVMKGGEAVCLYEEP
VSELLRRCGNCTRESCVVSFYLSADHELLSPTNYHFLSSPKEAVGLCKAQITAIISQQGDIFVFDLETSAVAPFVWLDVGSIPGRFSDNG

--------------------------------------------------------------
>In-frame_ENST00000321805_ENST00000226578_TCGA-25-1632-01A_UBE2D3_chr4_103722611_-_MANBA_chr4_103611928_length(transcript)=2898nt_BP=767nt
GTAGTTCCGTCAGAGCGGACATCTTGTGGCTGTGTCGTGCGCGTGAGCCCCGTAGGGCCGGGGAGGCACCAGCTGCCGCGCGGGGAGGAG
GCCGAGGCCGCAGCTTGAGGGAGGCCCCGGCCCCTCTAGGCCGGGAAGTTAAACTTGTAGCCACCACCTCCGCTCTTCCCGTCACCCTCG
CCCCCACTTCGGGCCGAAAGCACGGTACAGAGGCTGTTGGTGGCTTTGCCACGCCACCCCACCCACCCCGGATCGCGGCTGTCTTAAGGG
ACCTGGATTCATCAGGGGCTCTTCGGGGCCTGTGCGAGTGCTGATCTGCTCCGTTTTTGCAAAAGGCGCCTGTGTCTGGCAGAGCTGGTG
TGAGACGAGACAATCCTGCCCCGCCGCCGGGATAATCAAGAGTTTTGGCCGGACCTTTGAGCATACACCGAGAGAGTGAGGAGCCAGACG
ACAAGCACACACTATGGCGCTGAAACGGATTAATAAGGAACTTAGTGATTTGGCCCGTGACCCTCCAGCACAATGTTCTGCAGGTCCAGT
TGGGGATGATATGTTTCATTGGCAAGCCACAATTATGGGACCTAATGACAGCCCATATCAAGGCGGTGTATTCTTTTTGACAATTCATTT
TCCTACAGACTACCCCTTCAAACCACCTAAGGTTGCATTTACAACAAGAATTTATCATCCAAATATTAACAGTAATGGCAGCATTTGTCT
CGATATTCTAAGATCACAGTGGTCGCCTGCTTTAACAATTTCTAAAGATAAGAGTGCCCAGGAGTGGAATCTGGAAATAGAGTCTACATT
TGATGTTGTCAGCTCAAAGCCAGTTGGTGGTCAAGTGATCGTAGCCATCCCTAAGTTGCAAACACAACAGACATACAGCATTGAACTTCA
ACCTGGGAAAAGGATTGTTGAGCTATTTGTGAACATTAGCAAGAATATTACTGTAGAAACTTGGTGGCCTCATGGACATGGAAACCAGAC
TGGGTACAACATGACTGTTCTTTTTGAACTGGATGGAGGCTTAAATATTGAAAAATCAGCTAAGGTTTATTTTAGGACAGTGGAACTTAT
AGAAGAGCCTATAAAAGGGTCTCCTGGTTTGAGTTTCTATTTCAAAATTAATGGATTTCCCATATTTCTAAAAGGCTCAAACTGGATCCC
AGCAGATTCATTCCAGGACCGAGTAACCTCTGAGTTGTTACGGCTCCTTTTACAGTCTGTTGTGGATGCTAATATGAATACTCTTCGGGT
TTGGGGAGGAGGAATTTATGAGCAGGATGAATTCTATGAACTCTGTGATGAACTAGGAATAATGGTATGGCAGGATTTTATGTTTGCCTG
TGCCCTTTATCCAACTGATCAGGGCTTCCTGGATTCAGTGACAGCAGAAGTTGCCTACCAGATCAAGAGACTGAAATCTCATCCTTCTAT
CATCATATGGAGTGGCAATAATGAAAATGAGGAGGCGCTGATGATGAATTGGTATCATATCAGTTTCACTGACCGGCCAATCTACATCAA
GGACTATGTGACACTCTATGTGAAAAACATCAGAGAGCTCGTACTGGCAGGAGACAAGAGTCGTCCTTTTATTACGTCCAGTCCTACAAA
TGGGGCTGAAACTGTTGCAGAAGCCTGGGTCTCTCAAAACCCTAATAGCAATTATTTTGGTGATGTACATTTTTATGACTATATCAGTGA
TTGCTGGAACTGGAAAGTTTTCCCAAAAGCTCGATTTGCATCTGAATATGGATATCAGTCCTGGCCGTCCTTCAGTACATTAGAAAAGGT
CTCGTCTACAGAGGACTGGTCTTTCAATAGCAAGTTTTCACTTCATCGACAACATCACGAAGGTGGTAACAAACAAATGCTTTATCAGGC
TGGACTTCATTTCAAACTCCCCCAAAGCACAGATCCATTACGCACATTTAAAGATACCATCTACCTTACTCAGGTGATGCAGGCCCAGTG
TGTCAAAACAGAAACTGAATTCTACCGCCGTAGTCGCAGCGAGATAGTGGATCAGCAAGGGCACACGATGGGGGCACTTTATTGGCAGTT
GAATGACATCTGGCAAGCTCCTTCCTGGGCTTCTCTTGAGTACGGAGGAAAGTGGAAAATGCTTCATTACTTTGCTCAGAATTTCTTTGC
TCCACTGTTGCCAGTAGGCTTTGAGAATGAAAACACGTTCTATATCTATGGTGTGTCAGATCTTCACTCGGATTATTCGATGACACTCAG
TGTGAGAGTCCATACATGGAGCTCCCTGGAGCCCGTGTGCTCTCGTGTGACTGAACGTTTTGTGATGAAAGGAGGAGAGGCTGTCTGCCT
TTATGAGGAGCCAGTGTCTGAATTGCTGAGGAGATGTGGGAATTGCACACGGGAAAGCTGTGTGGTTTCCTTTTACCTTTCAGCTGACCA
TGAACTCCTGAGCCCGACCAACTACCACTTCTTGTCCTCACCGAAGGAGGCCGTGGGGCTCTGCAAGGCGCAGATCACTGCCATCATCTC
TCAGCAAGGTGACATATTTGTTTTTGACCTGGAGACCTCAGCTGTCGCTCCCTTTGTTTGGTTGGATGTAGGAAGCATCCCAGGGAGATT
TAGTGACAATGGTTTCCTCATGACTGAGAAGACACGAACTATATTATTTTACCCTTGGGAGCCCACCAGCAAGAATGAGTTGGAGCAATC
TTTTCATGTGACCTCCTTAACAGATATTTACTGAAGGAATCTAGGTTGTATTTTCAGTGGACAATGGGAATAAAGCATTTCTAAAGCACC
GACTGGAGAGGAAGGCAACAGAGACAAGGAGAGAAGCCGAGAGACATGTCTGCGTGCTGCCACGCATTTGAGCGATTGCTCTGTGAAGAG

>In-frame_ENST00000321805_ENST00000226578_TCGA-25-1632-01A_UBE2D3_chr4_103722611_-_MANBA_chr4_103611928_length(amino acids)=756AA_start in transcript=463_stop in transcript=2733
MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR
SQWSPALTISKDKSAQEWNLEIESTFDVVSSKPVGGQVIVAIPKLQTQQTYSIELQPGKRIVELFVNISKNITVETWWPHGHGNQTGYNM
TVLFELDGGLNIEKSAKVYFRTVELIEEPIKGSPGLSFYFKINGFPIFLKGSNWIPADSFQDRVTSELLRLLLQSVVDANMNTLRVWGGG
IYEQDEFYELCDELGIMVWQDFMFACALYPTDQGFLDSVTAEVAYQIKRLKSHPSIIIWSGNNENEEALMMNWYHISFTDRPIYIKDYVT
LYVKNIRELVLAGDKSRPFITSSPTNGAETVAEAWVSQNPNSNYFGDVHFYDYISDCWNWKVFPKARFASEYGYQSWPSFSTLEKVSSTE
DWSFNSKFSLHRQHHEGGNKQMLYQAGLHFKLPQSTDPLRTFKDTIYLTQVMQAQCVKTETEFYRRSRSEIVDQQGHTMGALYWQLNDIW
QAPSWASLEYGGKWKMLHYFAQNFFAPLLPVGFENENTFYIYGVSDLHSDYSMTLSVRVHTWSSLEPVCSRVTERFVMKGGEAVCLYEEP
VSELLRRCGNCTRESCVVSFYLSADHELLSPTNYHFLSSPKEAVGLCKAQITAIISQQGDIFVFDLETSAVAPFVWLDVGSIPGRFSDNG

--------------------------------------------------------------
>In-frame_ENST00000321805_ENST00000505239_TCGA-25-1632-01A_UBE2D3_chr4_103722611_-_MANBA_chr4_103611928_length(transcript)=2803nt_BP=767nt
GTAGTTCCGTCAGAGCGGACATCTTGTGGCTGTGTCGTGCGCGTGAGCCCCGTAGGGCCGGGGAGGCACCAGCTGCCGCGCGGGGAGGAG
GCCGAGGCCGCAGCTTGAGGGAGGCCCCGGCCCCTCTAGGCCGGGAAGTTAAACTTGTAGCCACCACCTCCGCTCTTCCCGTCACCCTCG
CCCCCACTTCGGGCCGAAAGCACGGTACAGAGGCTGTTGGTGGCTTTGCCACGCCACCCCACCCACCCCGGATCGCGGCTGTCTTAAGGG
ACCTGGATTCATCAGGGGCTCTTCGGGGCCTGTGCGAGTGCTGATCTGCTCCGTTTTTGCAAAAGGCGCCTGTGTCTGGCAGAGCTGGTG
TGAGACGAGACAATCCTGCCCCGCCGCCGGGATAATCAAGAGTTTTGGCCGGACCTTTGAGCATACACCGAGAGAGTGAGGAGCCAGACG
ACAAGCACACACTATGGCGCTGAAACGGATTAATAAGGAACTTAGTGATTTGGCCCGTGACCCTCCAGCACAATGTTCTGCAGGTCCAGT
TGGGGATGATATGTTTCATTGGCAAGCCACAATTATGGGACCTAATGACAGCCCATATCAAGGCGGTGTATTCTTTTTGACAATTCATTT
TCCTACAGACTACCCCTTCAAACCACCTAAGGTTGCATTTACAACAAGAATTTATCATCCAAATATTAACAGTAATGGCAGCATTTGTCT
CGATATTCTAAGATCACAGTGGTCGCCTGCTTTAACAATTTCTAAAGATAAGAGTGCCCAGGAGTGGAATCTGGAAATAGAGTCTACATT
TGATGTTGTCAGCTCAAAGCCAGTTGGTGGTCAAGTGATCGTAGCCATCCCTAAGTTGCAAACACAACAGACATACAGCATTGAACTTCA
ACCTGGGAAAAGGATTGTTGAGCTATTTGTGAACATTAGCAAGAATATTACTGTAGAAACTTGGTGGCCTCATGGACATGGAAACCAGAC
TGGGTACAACATGACTGTTCTTTTTGAACTGGATGGAGGCTTAAATATTGAAAAATCAGCTAAGGTTTATTTTAGGACAGTGGAACTTAT
AGAAGAGCCTATAAAAGGGTCTCCTGGTTTGAGTTTCTATTTCAAAATTAATGGATTTCCCATATTTCTAAAAGGCTCAAACTGGATCCC
AGCAGATTCATTCCAGGACCGAGTAACCTCTGAGTTGTTACGGCTCCTTTTACAGTCTGTTGTGGATGCTAATATGAATACTCTTCGGGT
TTGGGGAGGAGGAATTTATGAGCAGGATGAATTCTATGAACTCTGTGATGAACTAGGAATAATGGTATGGCAGGATTTTATGTTTGCCTG
TGCCCTTTATCCAACTGATCAGGGCTTCCTGGATTCAGTGACAGCAGAAGTTGCCTACCAGATCAAGAGACTGAAATCTCATCCTTCTAT
CATCATATGGAGTGGCAATAATGAAAATGAGGAGGCGCTGATGATGAATTGGTATCATATCAGTTTCACTGACCGGCCAATCTACATCAA
GGACTATGTGACACTCTATGTGAAAAACATCAGAGAGCTCGTACTGGCAGGAGACAAGAGTCGTCCTTTTATTACGTCCAGTCCTACAAA
TGGGGCTGAAACTGTTGCAGAAGCCTGGGTCTCTCAAAACCCTAATAGCAATTATTTTGGTGATGTACATTTTTATGACTATATCAGTGA
TTGCTGGAACTGGAAAGTTTTCCCAAAAGCTCGATTTGCATCTGAATATGGATATCAGTCCTGGCCGTCCTTCAGTACATTAGAAAAGGT
CTCGTCTACAGAGGACTGGTCTTTCAATAGCAAGTTTTCACTTCATCGACAACATCACGAAGGTGGTAACAAACAAATGCTTTATCAGGC
TGGACTTCATTTCAAACTCCCCCAAAGCACAGATCCATTACGCACATTTAAAGATACCATCTACCTTACTCAGGTGATGCAGGCCCAGTG
TGTCAAAACAGAAACTGAATTCTACCGCCGTAGTCGCAGCGAGATAGTGGATCAGCAAGGGCACACGATGGGGGCACTTTATTGGCAGTT
GAATGACATCTGGCAAGCTCCTTCCTGGGCTTCTCTTGAGTACGGAGGAAAGTGGAAAATGCTTCATTACTTTGCTCAGAATTTCTTTGC
TCCACTGTTGCCAGTAGGCTTTGAGAATGAAAACACGTTCTATATCTATGGTGTGTCAGATCTTCACTCGGATTATTCGATGACACTCAG
TGTGAGAGTCCATACATGGAGCTCCCTGGAGCCCGTGTGCTCTCGTGTGACTGAACGTTTTGTGATGAAAGGAGGAGAGGCTGTCTGCCT
TTATGAGGAGCCAGTGTCTGAATTGCTGAGGAGATGTGGGAATTGCACACGGGAAAGCTGTGTGGTTTCCTTTTACCTTTCAGCTGACCA
TGAACTCCTGAGCCCGACCAACTACCACTTCTTGTCCTCACCGAAGGAGGCCGTGGGGCTCTGCAAGGCGCAGATCACTGCCATCATCTC
TCAGCAAGGTGACATATTTGTTTTTGACCTGGAGACCTCAGCTGTCGCTCCCTTTGTTTGGTTGGATGTAGGAAGCATCCCAGGGAGATT
TAGTGACAATGGTTTCCTCATGACTGAGAAGACACGAACTATATTATTTTACCCTTGGGAGCCCACCAGCAAGAATGAGTTGGAGCAATC
TTTTCATGTGACCTCCTTAACAGATATTTACTGAAGGAATCTAGGTTGTATTTTCAGTGGACAATGGGAATAAAGCATTTCTAAAGCACC

>In-frame_ENST00000321805_ENST00000505239_TCGA-25-1632-01A_UBE2D3_chr4_103722611_-_MANBA_chr4_103611928_length(amino acids)=756AA_start in transcript=463_stop in transcript=2733
MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR
SQWSPALTISKDKSAQEWNLEIESTFDVVSSKPVGGQVIVAIPKLQTQQTYSIELQPGKRIVELFVNISKNITVETWWPHGHGNQTGYNM
TVLFELDGGLNIEKSAKVYFRTVELIEEPIKGSPGLSFYFKINGFPIFLKGSNWIPADSFQDRVTSELLRLLLQSVVDANMNTLRVWGGG
IYEQDEFYELCDELGIMVWQDFMFACALYPTDQGFLDSVTAEVAYQIKRLKSHPSIIIWSGNNENEEALMMNWYHISFTDRPIYIKDYVT
LYVKNIRELVLAGDKSRPFITSSPTNGAETVAEAWVSQNPNSNYFGDVHFYDYISDCWNWKVFPKARFASEYGYQSWPSFSTLEKVSSTE
DWSFNSKFSLHRQHHEGGNKQMLYQAGLHFKLPQSTDPLRTFKDTIYLTQVMQAQCVKTETEFYRRSRSEIVDQQGHTMGALYWQLNDIW
QAPSWASLEYGGKWKMLHYFAQNFFAPLLPVGFENENTFYIYGVSDLHSDYSMTLSVRVHTWSSLEPVCSRVTERFVMKGGEAVCLYEEP
VSELLRRCGNCTRESCVVSFYLSADHELLSPTNYHFLSSPKEAVGLCKAQITAIISQQGDIFVFDLETSAVAPFVWLDVGSIPGRFSDNG

--------------------------------------------------------------
>In-frame_ENST00000350435_ENST00000226578_TCGA-25-1632-01A_UBE2D3_chr4_103722611_-_MANBA_chr4_103611928_length(transcript)=2534nt_BP=403nt
AGTTGCAGCTTTTCACCCGAAGCTATTTATCCGAGGGACACCGGGAACTGATGTAAAAGGCATTCTGGAAGCTCCCTTTTCCTTTTGGCT
GGAGAGTGGGGGTGGATAAGGGGTGCGATGGCAGAACTTAGTGATTTGGCCCGTGACCCTCCAGCACAATGTTCTGCAGGTCCAGTTGGG
GATGATATGTTTCATTGGCAAGCCACAATTATGGGACCTAATGACAGCCCATATCAAGGCGGTGTATTCTTTTTGACAATTCATTTTCCT
ACAGACTACCCCTTCAAACCACCTAAGGTTGCATTTACAACAAGAATTTATCATCCAAATATTAACAGTAATGGCAGCATTTGTCTCGAT
ATTCTAAGATCACAGTGGTCGCCTGCTTTAACAATTTCTAAAGATAAGAGTGCCCAGGAGTGGAATCTGGAAATAGAGTCTACATTTGAT
GTTGTCAGCTCAAAGCCAGTTGGTGGTCAAGTGATCGTAGCCATCCCTAAGTTGCAAACACAACAGACATACAGCATTGAACTTCAACCT
GGGAAAAGGATTGTTGAGCTATTTGTGAACATTAGCAAGAATATTACTGTAGAAACTTGGTGGCCTCATGGACATGGAAACCAGACTGGG
TACAACATGACTGTTCTTTTTGAACTGGATGGAGGCTTAAATATTGAAAAATCAGCTAAGGTTTATTTTAGGACAGTGGAACTTATAGAA
GAGCCTATAAAAGGGTCTCCTGGTTTGAGTTTCTATTTCAAAATTAATGGATTTCCCATATTTCTAAAAGGCTCAAACTGGATCCCAGCA
GATTCATTCCAGGACCGAGTAACCTCTGAGTTGTTACGGCTCCTTTTACAGTCTGTTGTGGATGCTAATATGAATACTCTTCGGGTTTGG
GGAGGAGGAATTTATGAGCAGGATGAATTCTATGAACTCTGTGATGAACTAGGAATAATGGTATGGCAGGATTTTATGTTTGCCTGTGCC
CTTTATCCAACTGATCAGGGCTTCCTGGATTCAGTGACAGCAGAAGTTGCCTACCAGATCAAGAGACTGAAATCTCATCCTTCTATCATC
ATATGGAGTGGCAATAATGAAAATGAGGAGGCGCTGATGATGAATTGGTATCATATCAGTTTCACTGACCGGCCAATCTACATCAAGGAC
TATGTGACACTCTATGTGAAAAACATCAGAGAGCTCGTACTGGCAGGAGACAAGAGTCGTCCTTTTATTACGTCCAGTCCTACAAATGGG
GCTGAAACTGTTGCAGAAGCCTGGGTCTCTCAAAACCCTAATAGCAATTATTTTGGTGATGTACATTTTTATGACTATATCAGTGATTGC
TGGAACTGGAAAGTTTTCCCAAAAGCTCGATTTGCATCTGAATATGGATATCAGTCCTGGCCGTCCTTCAGTACATTAGAAAAGGTCTCG
TCTACAGAGGACTGGTCTTTCAATAGCAAGTTTTCACTTCATCGACAACATCACGAAGGTGGTAACAAACAAATGCTTTATCAGGCTGGA
CTTCATTTCAAACTCCCCCAAAGCACAGATCCATTACGCACATTTAAAGATACCATCTACCTTACTCAGGTGATGCAGGCCCAGTGTGTC
AAAACAGAAACTGAATTCTACCGCCGTAGTCGCAGCGAGATAGTGGATCAGCAAGGGCACACGATGGGGGCACTTTATTGGCAGTTGAAT
GACATCTGGCAAGCTCCTTCCTGGGCTTCTCTTGAGTACGGAGGAAAGTGGAAAATGCTTCATTACTTTGCTCAGAATTTCTTTGCTCCA
CTGTTGCCAGTAGGCTTTGAGAATGAAAACACGTTCTATATCTATGGTGTGTCAGATCTTCACTCGGATTATTCGATGACACTCAGTGTG
AGAGTCCATACATGGAGCTCCCTGGAGCCCGTGTGCTCTCGTGTGACTGAACGTTTTGTGATGAAAGGAGGAGAGGCTGTCTGCCTTTAT
GAGGAGCCAGTGTCTGAATTGCTGAGGAGATGTGGGAATTGCACACGGGAAAGCTGTGTGGTTTCCTTTTACCTTTCAGCTGACCATGAA
CTCCTGAGCCCGACCAACTACCACTTCTTGTCCTCACCGAAGGAGGCCGTGGGGCTCTGCAAGGCGCAGATCACTGCCATCATCTCTCAG
CAAGGTGACATATTTGTTTTTGACCTGGAGACCTCAGCTGTCGCTCCCTTTGTTTGGTTGGATGTAGGAAGCATCCCAGGGAGATTTAGT
GACAATGGTTTCCTCATGACTGAGAAGACACGAACTATATTATTTTACCCTTGGGAGCCCACCAGCAAGAATGAGTTGGAGCAATCTTTT
CATGTGACCTCCTTAACAGATATTTACTGAAGGAATCTAGGTTGTATTTTCAGTGGACAATGGGAATAAAGCATTTCTAAAGCACCGACT
GGAGAGGAAGGCAACAGAGACAAGGAGAGAAGCCGAGAGACATGTCTGCGTGCTGCCACGCATTTGAGCGATTGCTCTGTGAAGAGTTGT

>In-frame_ENST00000350435_ENST00000226578_TCGA-25-1632-01A_UBE2D3_chr4_103722611_-_MANBA_chr4_103611928_length(amino acids)=761AA_start in transcript=84_stop in transcript=2369
MAGEWGWIRGAMAELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSIC
LDILRSQWSPALTISKDKSAQEWNLEIESTFDVVSSKPVGGQVIVAIPKLQTQQTYSIELQPGKRIVELFVNISKNITVETWWPHGHGNQ
TGYNMTVLFELDGGLNIEKSAKVYFRTVELIEEPIKGSPGLSFYFKINGFPIFLKGSNWIPADSFQDRVTSELLRLLLQSVVDANMNTLR
VWGGGIYEQDEFYELCDELGIMVWQDFMFACALYPTDQGFLDSVTAEVAYQIKRLKSHPSIIIWSGNNENEEALMMNWYHISFTDRPIYI
KDYVTLYVKNIRELVLAGDKSRPFITSSPTNGAETVAEAWVSQNPNSNYFGDVHFYDYISDCWNWKVFPKARFASEYGYQSWPSFSTLEK
VSSTEDWSFNSKFSLHRQHHEGGNKQMLYQAGLHFKLPQSTDPLRTFKDTIYLTQVMQAQCVKTETEFYRRSRSEIVDQQGHTMGALYWQ
LNDIWQAPSWASLEYGGKWKMLHYFAQNFFAPLLPVGFENENTFYIYGVSDLHSDYSMTLSVRVHTWSSLEPVCSRVTERFVMKGGEAVC
LYEEPVSELLRRCGNCTRESCVVSFYLSADHELLSPTNYHFLSSPKEAVGLCKAQITAIISQQGDIFVFDLETSAVAPFVWLDVGSIPGR

--------------------------------------------------------------
>In-frame_ENST00000350435_ENST00000505239_TCGA-25-1632-01A_UBE2D3_chr4_103722611_-_MANBA_chr4_103611928_length(transcript)=2439nt_BP=403nt
AGTTGCAGCTTTTCACCCGAAGCTATTTATCCGAGGGACACCGGGAACTGATGTAAAAGGCATTCTGGAAGCTCCCTTTTCCTTTTGGCT
GGAGAGTGGGGGTGGATAAGGGGTGCGATGGCAGAACTTAGTGATTTGGCCCGTGACCCTCCAGCACAATGTTCTGCAGGTCCAGTTGGG
GATGATATGTTTCATTGGCAAGCCACAATTATGGGACCTAATGACAGCCCATATCAAGGCGGTGTATTCTTTTTGACAATTCATTTTCCT
ACAGACTACCCCTTCAAACCACCTAAGGTTGCATTTACAACAAGAATTTATCATCCAAATATTAACAGTAATGGCAGCATTTGTCTCGAT
ATTCTAAGATCACAGTGGTCGCCTGCTTTAACAATTTCTAAAGATAAGAGTGCCCAGGAGTGGAATCTGGAAATAGAGTCTACATTTGAT
GTTGTCAGCTCAAAGCCAGTTGGTGGTCAAGTGATCGTAGCCATCCCTAAGTTGCAAACACAACAGACATACAGCATTGAACTTCAACCT
GGGAAAAGGATTGTTGAGCTATTTGTGAACATTAGCAAGAATATTACTGTAGAAACTTGGTGGCCTCATGGACATGGAAACCAGACTGGG
TACAACATGACTGTTCTTTTTGAACTGGATGGAGGCTTAAATATTGAAAAATCAGCTAAGGTTTATTTTAGGACAGTGGAACTTATAGAA
GAGCCTATAAAAGGGTCTCCTGGTTTGAGTTTCTATTTCAAAATTAATGGATTTCCCATATTTCTAAAAGGCTCAAACTGGATCCCAGCA
GATTCATTCCAGGACCGAGTAACCTCTGAGTTGTTACGGCTCCTTTTACAGTCTGTTGTGGATGCTAATATGAATACTCTTCGGGTTTGG
GGAGGAGGAATTTATGAGCAGGATGAATTCTATGAACTCTGTGATGAACTAGGAATAATGGTATGGCAGGATTTTATGTTTGCCTGTGCC
CTTTATCCAACTGATCAGGGCTTCCTGGATTCAGTGACAGCAGAAGTTGCCTACCAGATCAAGAGACTGAAATCTCATCCTTCTATCATC
ATATGGAGTGGCAATAATGAAAATGAGGAGGCGCTGATGATGAATTGGTATCATATCAGTTTCACTGACCGGCCAATCTACATCAAGGAC
TATGTGACACTCTATGTGAAAAACATCAGAGAGCTCGTACTGGCAGGAGACAAGAGTCGTCCTTTTATTACGTCCAGTCCTACAAATGGG
GCTGAAACTGTTGCAGAAGCCTGGGTCTCTCAAAACCCTAATAGCAATTATTTTGGTGATGTACATTTTTATGACTATATCAGTGATTGC
TGGAACTGGAAAGTTTTCCCAAAAGCTCGATTTGCATCTGAATATGGATATCAGTCCTGGCCGTCCTTCAGTACATTAGAAAAGGTCTCG
TCTACAGAGGACTGGTCTTTCAATAGCAAGTTTTCACTTCATCGACAACATCACGAAGGTGGTAACAAACAAATGCTTTATCAGGCTGGA
CTTCATTTCAAACTCCCCCAAAGCACAGATCCATTACGCACATTTAAAGATACCATCTACCTTACTCAGGTGATGCAGGCCCAGTGTGTC
AAAACAGAAACTGAATTCTACCGCCGTAGTCGCAGCGAGATAGTGGATCAGCAAGGGCACACGATGGGGGCACTTTATTGGCAGTTGAAT
GACATCTGGCAAGCTCCTTCCTGGGCTTCTCTTGAGTACGGAGGAAAGTGGAAAATGCTTCATTACTTTGCTCAGAATTTCTTTGCTCCA
CTGTTGCCAGTAGGCTTTGAGAATGAAAACACGTTCTATATCTATGGTGTGTCAGATCTTCACTCGGATTATTCGATGACACTCAGTGTG
AGAGTCCATACATGGAGCTCCCTGGAGCCCGTGTGCTCTCGTGTGACTGAACGTTTTGTGATGAAAGGAGGAGAGGCTGTCTGCCTTTAT
GAGGAGCCAGTGTCTGAATTGCTGAGGAGATGTGGGAATTGCACACGGGAAAGCTGTGTGGTTTCCTTTTACCTTTCAGCTGACCATGAA
CTCCTGAGCCCGACCAACTACCACTTCTTGTCCTCACCGAAGGAGGCCGTGGGGCTCTGCAAGGCGCAGATCACTGCCATCATCTCTCAG
CAAGGTGACATATTTGTTTTTGACCTGGAGACCTCAGCTGTCGCTCCCTTTGTTTGGTTGGATGTAGGAAGCATCCCAGGGAGATTTAGT
GACAATGGTTTCCTCATGACTGAGAAGACACGAACTATATTATTTTACCCTTGGGAGCCCACCAGCAAGAATGAGTTGGAGCAATCTTTT
CATGTGACCTCCTTAACAGATATTTACTGAAGGAATCTAGGTTGTATTTTCAGTGGACAATGGGAATAAAGCATTTCTAAAGCACCGACT

>In-frame_ENST00000350435_ENST00000505239_TCGA-25-1632-01A_UBE2D3_chr4_103722611_-_MANBA_chr4_103611928_length(amino acids)=761AA_start in transcript=84_stop in transcript=2369
MAGEWGWIRGAMAELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSIC
LDILRSQWSPALTISKDKSAQEWNLEIESTFDVVSSKPVGGQVIVAIPKLQTQQTYSIELQPGKRIVELFVNISKNITVETWWPHGHGNQ
TGYNMTVLFELDGGLNIEKSAKVYFRTVELIEEPIKGSPGLSFYFKINGFPIFLKGSNWIPADSFQDRVTSELLRLLLQSVVDANMNTLR
VWGGGIYEQDEFYELCDELGIMVWQDFMFACALYPTDQGFLDSVTAEVAYQIKRLKSHPSIIIWSGNNENEEALMMNWYHISFTDRPIYI
KDYVTLYVKNIRELVLAGDKSRPFITSSPTNGAETVAEAWVSQNPNSNYFGDVHFYDYISDCWNWKVFPKARFASEYGYQSWPSFSTLEK
VSSTEDWSFNSKFSLHRQHHEGGNKQMLYQAGLHFKLPQSTDPLRTFKDTIYLTQVMQAQCVKTETEFYRRSRSEIVDQQGHTMGALYWQ
LNDIWQAPSWASLEYGGKWKMLHYFAQNFFAPLLPVGFENENTFYIYGVSDLHSDYSMTLSVRVHTWSSLEPVCSRVTERFVMKGGEAVC
LYEEPVSELLRRCGNCTRESCVVSFYLSADHELLSPTNYHFLSSPKEAVGLCKAQITAIISQQGDIFVFDLETSAVAPFVWLDVGSIPGR

--------------------------------------------------------------
>In-frame_ENST00000338145_ENST00000226578_TCGA-25-1632-01A_UBE2D3_chr4_103722611_-_MANBA_chr4_103611928_length(transcript)=2724nt_BP=593nt
GGGAACTGGCGGGTAGCGAGGCCCTCCTCGGAATCTCGTGTGAAGGTGGCCCTCCTCTTGGGCCTTTAACGTCTGTAGATGCTGGAGACC
AGCAGAAAGGATACTGTGTGCGATGAGATAAGCATGTGAGAATGCTTTCTAACCGAAAGTGCCTTTCAAAAGCGCCTGTGTCTGGCAGAG
CTGGTGTGAGACGAGACAATCCTGCCCCGCCGCCGGGATAATCAAGAGTTTTGGCCGGACCTTTGAGCATACACCGAGAGAGTGAGGAGC
CAGACGACAAGCACACACTATGGCGCTGAAACGGATTAATAAGGAACTTAGTGATTTGGCCCGTGACCCTCCAGCACAATGTTCTGCAGG
TCCAGTTGGGGATGATATGTTTCATTGGCAAGCCACAATTATGGGACCTAATGACAGCCCATATCAAGGCGGTGTATTCTTTTTGACAAT
TCATTTTCCTACAGACTACCCCTTCAAACCACCTAAGGTTGCATTTACAACAAGAATTTATCATCCAAATATTAACAGTAATGGCAGCAT
TTGTCTCGATATTCTAAGATCACAGTGGTCGCCTGCTTTAACAATTTCTAAAGATAAGAGTGCCCAGGAGTGGAATCTGGAAATAGAGTC
TACATTTGATGTTGTCAGCTCAAAGCCAGTTGGTGGTCAAGTGATCGTAGCCATCCCTAAGTTGCAAACACAACAGACATACAGCATTGA
ACTTCAACCTGGGAAAAGGATTGTTGAGCTATTTGTGAACATTAGCAAGAATATTACTGTAGAAACTTGGTGGCCTCATGGACATGGAAA
CCAGACTGGGTACAACATGACTGTTCTTTTTGAACTGGATGGAGGCTTAAATATTGAAAAATCAGCTAAGGTTTATTTTAGGACAGTGGA
ACTTATAGAAGAGCCTATAAAAGGGTCTCCTGGTTTGAGTTTCTATTTCAAAATTAATGGATTTCCCATATTTCTAAAAGGCTCAAACTG
GATCCCAGCAGATTCATTCCAGGACCGAGTAACCTCTGAGTTGTTACGGCTCCTTTTACAGTCTGTTGTGGATGCTAATATGAATACTCT
TCGGGTTTGGGGAGGAGGAATTTATGAGCAGGATGAATTCTATGAACTCTGTGATGAACTAGGAATAATGGTATGGCAGGATTTTATGTT
TGCCTGTGCCCTTTATCCAACTGATCAGGGCTTCCTGGATTCAGTGACAGCAGAAGTTGCCTACCAGATCAAGAGACTGAAATCTCATCC
TTCTATCATCATATGGAGTGGCAATAATGAAAATGAGGAGGCGCTGATGATGAATTGGTATCATATCAGTTTCACTGACCGGCCAATCTA
CATCAAGGACTATGTGACACTCTATGTGAAAAACATCAGAGAGCTCGTACTGGCAGGAGACAAGAGTCGTCCTTTTATTACGTCCAGTCC
TACAAATGGGGCTGAAACTGTTGCAGAAGCCTGGGTCTCTCAAAACCCTAATAGCAATTATTTTGGTGATGTACATTTTTATGACTATAT
CAGTGATTGCTGGAACTGGAAAGTTTTCCCAAAAGCTCGATTTGCATCTGAATATGGATATCAGTCCTGGCCGTCCTTCAGTACATTAGA
AAAGGTCTCGTCTACAGAGGACTGGTCTTTCAATAGCAAGTTTTCACTTCATCGACAACATCACGAAGGTGGTAACAAACAAATGCTTTA
TCAGGCTGGACTTCATTTCAAACTCCCCCAAAGCACAGATCCATTACGCACATTTAAAGATACCATCTACCTTACTCAGGTGATGCAGGC
CCAGTGTGTCAAAACAGAAACTGAATTCTACCGCCGTAGTCGCAGCGAGATAGTGGATCAGCAAGGGCACACGATGGGGGCACTTTATTG
GCAGTTGAATGACATCTGGCAAGCTCCTTCCTGGGCTTCTCTTGAGTACGGAGGAAAGTGGAAAATGCTTCATTACTTTGCTCAGAATTT
CTTTGCTCCACTGTTGCCAGTAGGCTTTGAGAATGAAAACACGTTCTATATCTATGGTGTGTCAGATCTTCACTCGGATTATTCGATGAC
ACTCAGTGTGAGAGTCCATACATGGAGCTCCCTGGAGCCCGTGTGCTCTCGTGTGACTGAACGTTTTGTGATGAAAGGAGGAGAGGCTGT
CTGCCTTTATGAGGAGCCAGTGTCTGAATTGCTGAGGAGATGTGGGAATTGCACACGGGAAAGCTGTGTGGTTTCCTTTTACCTTTCAGC
TGACCATGAACTCCTGAGCCCGACCAACTACCACTTCTTGTCCTCACCGAAGGAGGCCGTGGGGCTCTGCAAGGCGCAGATCACTGCCAT
CATCTCTCAGCAAGGTGACATATTTGTTTTTGACCTGGAGACCTCAGCTGTCGCTCCCTTTGTTTGGTTGGATGTAGGAAGCATCCCAGG
GAGATTTAGTGACAATGGTTTCCTCATGACTGAGAAGACACGAACTATATTATTTTACCCTTGGGAGCCCACCAGCAAGAATGAGTTGGA
GCAATCTTTTCATGTGACCTCCTTAACAGATATTTACTGAAGGAATCTAGGTTGTATTTTCAGTGGACAATGGGAATAAAGCATTTCTAA
AGCACCGACTGGAGAGGAAGGCAACAGAGACAAGGAGAGAAGCCGAGAGACATGTCTGCGTGCTGCCACGCATTTGAGCGATTGCTCTGT

>In-frame_ENST00000338145_ENST00000226578_TCGA-25-1632-01A_UBE2D3_chr4_103722611_-_MANBA_chr4_103611928_length(amino acids)=756AA_start in transcript=289_stop in transcript=2559
MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR
SQWSPALTISKDKSAQEWNLEIESTFDVVSSKPVGGQVIVAIPKLQTQQTYSIELQPGKRIVELFVNISKNITVETWWPHGHGNQTGYNM
TVLFELDGGLNIEKSAKVYFRTVELIEEPIKGSPGLSFYFKINGFPIFLKGSNWIPADSFQDRVTSELLRLLLQSVVDANMNTLRVWGGG
IYEQDEFYELCDELGIMVWQDFMFACALYPTDQGFLDSVTAEVAYQIKRLKSHPSIIIWSGNNENEEALMMNWYHISFTDRPIYIKDYVT
LYVKNIRELVLAGDKSRPFITSSPTNGAETVAEAWVSQNPNSNYFGDVHFYDYISDCWNWKVFPKARFASEYGYQSWPSFSTLEKVSSTE
DWSFNSKFSLHRQHHEGGNKQMLYQAGLHFKLPQSTDPLRTFKDTIYLTQVMQAQCVKTETEFYRRSRSEIVDQQGHTMGALYWQLNDIW
QAPSWASLEYGGKWKMLHYFAQNFFAPLLPVGFENENTFYIYGVSDLHSDYSMTLSVRVHTWSSLEPVCSRVTERFVMKGGEAVCLYEEP
VSELLRRCGNCTRESCVVSFYLSADHELLSPTNYHFLSSPKEAVGLCKAQITAIISQQGDIFVFDLETSAVAPFVWLDVGSIPGRFSDNG

--------------------------------------------------------------
>In-frame_ENST00000338145_ENST00000505239_TCGA-25-1632-01A_UBE2D3_chr4_103722611_-_MANBA_chr4_103611928_length(transcript)=2629nt_BP=593nt
GGGAACTGGCGGGTAGCGAGGCCCTCCTCGGAATCTCGTGTGAAGGTGGCCCTCCTCTTGGGCCTTTAACGTCTGTAGATGCTGGAGACC
AGCAGAAAGGATACTGTGTGCGATGAGATAAGCATGTGAGAATGCTTTCTAACCGAAAGTGCCTTTCAAAAGCGCCTGTGTCTGGCAGAG
CTGGTGTGAGACGAGACAATCCTGCCCCGCCGCCGGGATAATCAAGAGTTTTGGCCGGACCTTTGAGCATACACCGAGAGAGTGAGGAGC
CAGACGACAAGCACACACTATGGCGCTGAAACGGATTAATAAGGAACTTAGTGATTTGGCCCGTGACCCTCCAGCACAATGTTCTGCAGG
TCCAGTTGGGGATGATATGTTTCATTGGCAAGCCACAATTATGGGACCTAATGACAGCCCATATCAAGGCGGTGTATTCTTTTTGACAAT
TCATTTTCCTACAGACTACCCCTTCAAACCACCTAAGGTTGCATTTACAACAAGAATTTATCATCCAAATATTAACAGTAATGGCAGCAT
TTGTCTCGATATTCTAAGATCACAGTGGTCGCCTGCTTTAACAATTTCTAAAGATAAGAGTGCCCAGGAGTGGAATCTGGAAATAGAGTC
TACATTTGATGTTGTCAGCTCAAAGCCAGTTGGTGGTCAAGTGATCGTAGCCATCCCTAAGTTGCAAACACAACAGACATACAGCATTGA
ACTTCAACCTGGGAAAAGGATTGTTGAGCTATTTGTGAACATTAGCAAGAATATTACTGTAGAAACTTGGTGGCCTCATGGACATGGAAA
CCAGACTGGGTACAACATGACTGTTCTTTTTGAACTGGATGGAGGCTTAAATATTGAAAAATCAGCTAAGGTTTATTTTAGGACAGTGGA
ACTTATAGAAGAGCCTATAAAAGGGTCTCCTGGTTTGAGTTTCTATTTCAAAATTAATGGATTTCCCATATTTCTAAAAGGCTCAAACTG
GATCCCAGCAGATTCATTCCAGGACCGAGTAACCTCTGAGTTGTTACGGCTCCTTTTACAGTCTGTTGTGGATGCTAATATGAATACTCT
TCGGGTTTGGGGAGGAGGAATTTATGAGCAGGATGAATTCTATGAACTCTGTGATGAACTAGGAATAATGGTATGGCAGGATTTTATGTT
TGCCTGTGCCCTTTATCCAACTGATCAGGGCTTCCTGGATTCAGTGACAGCAGAAGTTGCCTACCAGATCAAGAGACTGAAATCTCATCC
TTCTATCATCATATGGAGTGGCAATAATGAAAATGAGGAGGCGCTGATGATGAATTGGTATCATATCAGTTTCACTGACCGGCCAATCTA
CATCAAGGACTATGTGACACTCTATGTGAAAAACATCAGAGAGCTCGTACTGGCAGGAGACAAGAGTCGTCCTTTTATTACGTCCAGTCC
TACAAATGGGGCTGAAACTGTTGCAGAAGCCTGGGTCTCTCAAAACCCTAATAGCAATTATTTTGGTGATGTACATTTTTATGACTATAT
CAGTGATTGCTGGAACTGGAAAGTTTTCCCAAAAGCTCGATTTGCATCTGAATATGGATATCAGTCCTGGCCGTCCTTCAGTACATTAGA
AAAGGTCTCGTCTACAGAGGACTGGTCTTTCAATAGCAAGTTTTCACTTCATCGACAACATCACGAAGGTGGTAACAAACAAATGCTTTA
TCAGGCTGGACTTCATTTCAAACTCCCCCAAAGCACAGATCCATTACGCACATTTAAAGATACCATCTACCTTACTCAGGTGATGCAGGC
CCAGTGTGTCAAAACAGAAACTGAATTCTACCGCCGTAGTCGCAGCGAGATAGTGGATCAGCAAGGGCACACGATGGGGGCACTTTATTG
GCAGTTGAATGACATCTGGCAAGCTCCTTCCTGGGCTTCTCTTGAGTACGGAGGAAAGTGGAAAATGCTTCATTACTTTGCTCAGAATTT
CTTTGCTCCACTGTTGCCAGTAGGCTTTGAGAATGAAAACACGTTCTATATCTATGGTGTGTCAGATCTTCACTCGGATTATTCGATGAC
ACTCAGTGTGAGAGTCCATACATGGAGCTCCCTGGAGCCCGTGTGCTCTCGTGTGACTGAACGTTTTGTGATGAAAGGAGGAGAGGCTGT
CTGCCTTTATGAGGAGCCAGTGTCTGAATTGCTGAGGAGATGTGGGAATTGCACACGGGAAAGCTGTGTGGTTTCCTTTTACCTTTCAGC
TGACCATGAACTCCTGAGCCCGACCAACTACCACTTCTTGTCCTCACCGAAGGAGGCCGTGGGGCTCTGCAAGGCGCAGATCACTGCCAT
CATCTCTCAGCAAGGTGACATATTTGTTTTTGACCTGGAGACCTCAGCTGTCGCTCCCTTTGTTTGGTTGGATGTAGGAAGCATCCCAGG
GAGATTTAGTGACAATGGTTTCCTCATGACTGAGAAGACACGAACTATATTATTTTACCCTTGGGAGCCCACCAGCAAGAATGAGTTGGA
GCAATCTTTTCATGTGACCTCCTTAACAGATATTTACTGAAGGAATCTAGGTTGTATTTTCAGTGGACAATGGGAATAAAGCATTTCTAA

>In-frame_ENST00000338145_ENST00000505239_TCGA-25-1632-01A_UBE2D3_chr4_103722611_-_MANBA_chr4_103611928_length(amino acids)=756AA_start in transcript=289_stop in transcript=2559
MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR
SQWSPALTISKDKSAQEWNLEIESTFDVVSSKPVGGQVIVAIPKLQTQQTYSIELQPGKRIVELFVNISKNITVETWWPHGHGNQTGYNM
TVLFELDGGLNIEKSAKVYFRTVELIEEPIKGSPGLSFYFKINGFPIFLKGSNWIPADSFQDRVTSELLRLLLQSVVDANMNTLRVWGGG
IYEQDEFYELCDELGIMVWQDFMFACALYPTDQGFLDSVTAEVAYQIKRLKSHPSIIIWSGNNENEEALMMNWYHISFTDRPIYIKDYVT
LYVKNIRELVLAGDKSRPFITSSPTNGAETVAEAWVSQNPNSNYFGDVHFYDYISDCWNWKVFPKARFASEYGYQSWPSFSTLEKVSSTE
DWSFNSKFSLHRQHHEGGNKQMLYQAGLHFKLPQSTDPLRTFKDTIYLTQVMQAQCVKTETEFYRRSRSEIVDQQGHTMGALYWQLNDIW
QAPSWASLEYGGKWKMLHYFAQNFFAPLLPVGFENENTFYIYGVSDLHSDYSMTLSVRVHTWSSLEPVCSRVTERFVMKGGEAVCLYEEP
VSELLRRCGNCTRESCVVSFYLSADHELLSPTNYHFLSSPKEAVGLCKAQITAIISQQGDIFVFDLETSAVAPFVWLDVGSIPGRFSDNG

--------------------------------------------------------------
>In-frame_ENST00000349311_ENST00000226578_TCGA-25-1632-01A_UBE2D3_chr4_103722611_-_MANBA_chr4_103611928_length(transcript)=2678nt_BP=547nt
CTCGATGCTTCTCTGAGCCTAAGGGTTTCCGCCACTCGTTCACCCTCCCCCCAGCTCATGATCCTCCTCCCTCCCCCGCCCTCCTGGTCC
AATCTCCGATCTGTTTAGTAAGAAGGCGCCTGTGTCTGGCAGAGCTGGTGTGAGACGAGACAATCCTGCCCCGCCGCCGGGATAATCAAG
AGTTTTGGCCGGACCTTTGAGCATACACCGAGAGAGTGAGGAGCCAGACGACAAGCACACACTATGGCGCTGAAACGGATTAATAAGGAA
CTTAGTGATTTGGCCCGTGACCCTCCAGCACAATGTTCTGCAGGTCCAGTTGGGGATGATATGTTTCATTGGCAAGCCACAATTATGGGA
CCTAATGACAGCCCATATCAAGGCGGTGTATTCTTTTTGACAATTCATTTTCCTACAGACTACCCCTTCAAACCACCTAAGGTTGCATTT
ACAACAAGAATTTATCATCCAAATATTAACAGTAATGGCAGCATTTGTCTCGATATTCTAAGATCACAGTGGTCGCCTGCTTTAACAATT
TCTAAAGATAAGAGTGCCCAGGAGTGGAATCTGGAAATAGAGTCTACATTTGATGTTGTCAGCTCAAAGCCAGTTGGTGGTCAAGTGATC
GTAGCCATCCCTAAGTTGCAAACACAACAGACATACAGCATTGAACTTCAACCTGGGAAAAGGATTGTTGAGCTATTTGTGAACATTAGC
AAGAATATTACTGTAGAAACTTGGTGGCCTCATGGACATGGAAACCAGACTGGGTACAACATGACTGTTCTTTTTGAACTGGATGGAGGC
TTAAATATTGAAAAATCAGCTAAGGTTTATTTTAGGACAGTGGAACTTATAGAAGAGCCTATAAAAGGGTCTCCTGGTTTGAGTTTCTAT
TTCAAAATTAATGGATTTCCCATATTTCTAAAAGGCTCAAACTGGATCCCAGCAGATTCATTCCAGGACCGAGTAACCTCTGAGTTGTTA
CGGCTCCTTTTACAGTCTGTTGTGGATGCTAATATGAATACTCTTCGGGTTTGGGGAGGAGGAATTTATGAGCAGGATGAATTCTATGAA
CTCTGTGATGAACTAGGAATAATGGTATGGCAGGATTTTATGTTTGCCTGTGCCCTTTATCCAACTGATCAGGGCTTCCTGGATTCAGTG
ACAGCAGAAGTTGCCTACCAGATCAAGAGACTGAAATCTCATCCTTCTATCATCATATGGAGTGGCAATAATGAAAATGAGGAGGCGCTG
ATGATGAATTGGTATCATATCAGTTTCACTGACCGGCCAATCTACATCAAGGACTATGTGACACTCTATGTGAAAAACATCAGAGAGCTC
GTACTGGCAGGAGACAAGAGTCGTCCTTTTATTACGTCCAGTCCTACAAATGGGGCTGAAACTGTTGCAGAAGCCTGGGTCTCTCAAAAC
CCTAATAGCAATTATTTTGGTGATGTACATTTTTATGACTATATCAGTGATTGCTGGAACTGGAAAGTTTTCCCAAAAGCTCGATTTGCA
TCTGAATATGGATATCAGTCCTGGCCGTCCTTCAGTACATTAGAAAAGGTCTCGTCTACAGAGGACTGGTCTTTCAATAGCAAGTTTTCA
CTTCATCGACAACATCACGAAGGTGGTAACAAACAAATGCTTTATCAGGCTGGACTTCATTTCAAACTCCCCCAAAGCACAGATCCATTA
CGCACATTTAAAGATACCATCTACCTTACTCAGGTGATGCAGGCCCAGTGTGTCAAAACAGAAACTGAATTCTACCGCCGTAGTCGCAGC
GAGATAGTGGATCAGCAAGGGCACACGATGGGGGCACTTTATTGGCAGTTGAATGACATCTGGCAAGCTCCTTCCTGGGCTTCTCTTGAG
TACGGAGGAAAGTGGAAAATGCTTCATTACTTTGCTCAGAATTTCTTTGCTCCACTGTTGCCAGTAGGCTTTGAGAATGAAAACACGTTC
TATATCTATGGTGTGTCAGATCTTCACTCGGATTATTCGATGACACTCAGTGTGAGAGTCCATACATGGAGCTCCCTGGAGCCCGTGTGC
TCTCGTGTGACTGAACGTTTTGTGATGAAAGGAGGAGAGGCTGTCTGCCTTTATGAGGAGCCAGTGTCTGAATTGCTGAGGAGATGTGGG
AATTGCACACGGGAAAGCTGTGTGGTTTCCTTTTACCTTTCAGCTGACCATGAACTCCTGAGCCCGACCAACTACCACTTCTTGTCCTCA
CCGAAGGAGGCCGTGGGGCTCTGCAAGGCGCAGATCACTGCCATCATCTCTCAGCAAGGTGACATATTTGTTTTTGACCTGGAGACCTCA
GCTGTCGCTCCCTTTGTTTGGTTGGATGTAGGAAGCATCCCAGGGAGATTTAGTGACAATGGTTTCCTCATGACTGAGAAGACACGAACT
ATATTATTTTACCCTTGGGAGCCCACCAGCAAGAATGAGTTGGAGCAATCTTTTCATGTGACCTCCTTAACAGATATTTACTGAAGGAAT
CTAGGTTGTATTTTCAGTGGACAATGGGAATAAAGCATTTCTAAAGCACCGACTGGAGAGGAAGGCAACAGAGACAAGGAGAGAAGCCGA

>In-frame_ENST00000349311_ENST00000226578_TCGA-25-1632-01A_UBE2D3_chr4_103722611_-_MANBA_chr4_103611928_length(amino acids)=756AA_start in transcript=243_stop in transcript=2513
MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR
SQWSPALTISKDKSAQEWNLEIESTFDVVSSKPVGGQVIVAIPKLQTQQTYSIELQPGKRIVELFVNISKNITVETWWPHGHGNQTGYNM
TVLFELDGGLNIEKSAKVYFRTVELIEEPIKGSPGLSFYFKINGFPIFLKGSNWIPADSFQDRVTSELLRLLLQSVVDANMNTLRVWGGG
IYEQDEFYELCDELGIMVWQDFMFACALYPTDQGFLDSVTAEVAYQIKRLKSHPSIIIWSGNNENEEALMMNWYHISFTDRPIYIKDYVT
LYVKNIRELVLAGDKSRPFITSSPTNGAETVAEAWVSQNPNSNYFGDVHFYDYISDCWNWKVFPKARFASEYGYQSWPSFSTLEKVSSTE
DWSFNSKFSLHRQHHEGGNKQMLYQAGLHFKLPQSTDPLRTFKDTIYLTQVMQAQCVKTETEFYRRSRSEIVDQQGHTMGALYWQLNDIW
QAPSWASLEYGGKWKMLHYFAQNFFAPLLPVGFENENTFYIYGVSDLHSDYSMTLSVRVHTWSSLEPVCSRVTERFVMKGGEAVCLYEEP
VSELLRRCGNCTRESCVVSFYLSADHELLSPTNYHFLSSPKEAVGLCKAQITAIISQQGDIFVFDLETSAVAPFVWLDVGSIPGRFSDNG

--------------------------------------------------------------
>In-frame_ENST00000349311_ENST00000505239_TCGA-25-1632-01A_UBE2D3_chr4_103722611_-_MANBA_chr4_103611928_length(transcript)=2583nt_BP=547nt
CTCGATGCTTCTCTGAGCCTAAGGGTTTCCGCCACTCGTTCACCCTCCCCCCAGCTCATGATCCTCCTCCCTCCCCCGCCCTCCTGGTCC
AATCTCCGATCTGTTTAGTAAGAAGGCGCCTGTGTCTGGCAGAGCTGGTGTGAGACGAGACAATCCTGCCCCGCCGCCGGGATAATCAAG
AGTTTTGGCCGGACCTTTGAGCATACACCGAGAGAGTGAGGAGCCAGACGACAAGCACACACTATGGCGCTGAAACGGATTAATAAGGAA
CTTAGTGATTTGGCCCGTGACCCTCCAGCACAATGTTCTGCAGGTCCAGTTGGGGATGATATGTTTCATTGGCAAGCCACAATTATGGGA
CCTAATGACAGCCCATATCAAGGCGGTGTATTCTTTTTGACAATTCATTTTCCTACAGACTACCCCTTCAAACCACCTAAGGTTGCATTT
ACAACAAGAATTTATCATCCAAATATTAACAGTAATGGCAGCATTTGTCTCGATATTCTAAGATCACAGTGGTCGCCTGCTTTAACAATT
TCTAAAGATAAGAGTGCCCAGGAGTGGAATCTGGAAATAGAGTCTACATTTGATGTTGTCAGCTCAAAGCCAGTTGGTGGTCAAGTGATC
GTAGCCATCCCTAAGTTGCAAACACAACAGACATACAGCATTGAACTTCAACCTGGGAAAAGGATTGTTGAGCTATTTGTGAACATTAGC
AAGAATATTACTGTAGAAACTTGGTGGCCTCATGGACATGGAAACCAGACTGGGTACAACATGACTGTTCTTTTTGAACTGGATGGAGGC
TTAAATATTGAAAAATCAGCTAAGGTTTATTTTAGGACAGTGGAACTTATAGAAGAGCCTATAAAAGGGTCTCCTGGTTTGAGTTTCTAT
TTCAAAATTAATGGATTTCCCATATTTCTAAAAGGCTCAAACTGGATCCCAGCAGATTCATTCCAGGACCGAGTAACCTCTGAGTTGTTA
CGGCTCCTTTTACAGTCTGTTGTGGATGCTAATATGAATACTCTTCGGGTTTGGGGAGGAGGAATTTATGAGCAGGATGAATTCTATGAA
CTCTGTGATGAACTAGGAATAATGGTATGGCAGGATTTTATGTTTGCCTGTGCCCTTTATCCAACTGATCAGGGCTTCCTGGATTCAGTG
ACAGCAGAAGTTGCCTACCAGATCAAGAGACTGAAATCTCATCCTTCTATCATCATATGGAGTGGCAATAATGAAAATGAGGAGGCGCTG
ATGATGAATTGGTATCATATCAGTTTCACTGACCGGCCAATCTACATCAAGGACTATGTGACACTCTATGTGAAAAACATCAGAGAGCTC
GTACTGGCAGGAGACAAGAGTCGTCCTTTTATTACGTCCAGTCCTACAAATGGGGCTGAAACTGTTGCAGAAGCCTGGGTCTCTCAAAAC
CCTAATAGCAATTATTTTGGTGATGTACATTTTTATGACTATATCAGTGATTGCTGGAACTGGAAAGTTTTCCCAAAAGCTCGATTTGCA
TCTGAATATGGATATCAGTCCTGGCCGTCCTTCAGTACATTAGAAAAGGTCTCGTCTACAGAGGACTGGTCTTTCAATAGCAAGTTTTCA
CTTCATCGACAACATCACGAAGGTGGTAACAAACAAATGCTTTATCAGGCTGGACTTCATTTCAAACTCCCCCAAAGCACAGATCCATTA
CGCACATTTAAAGATACCATCTACCTTACTCAGGTGATGCAGGCCCAGTGTGTCAAAACAGAAACTGAATTCTACCGCCGTAGTCGCAGC
GAGATAGTGGATCAGCAAGGGCACACGATGGGGGCACTTTATTGGCAGTTGAATGACATCTGGCAAGCTCCTTCCTGGGCTTCTCTTGAG
TACGGAGGAAAGTGGAAAATGCTTCATTACTTTGCTCAGAATTTCTTTGCTCCACTGTTGCCAGTAGGCTTTGAGAATGAAAACACGTTC
TATATCTATGGTGTGTCAGATCTTCACTCGGATTATTCGATGACACTCAGTGTGAGAGTCCATACATGGAGCTCCCTGGAGCCCGTGTGC
TCTCGTGTGACTGAACGTTTTGTGATGAAAGGAGGAGAGGCTGTCTGCCTTTATGAGGAGCCAGTGTCTGAATTGCTGAGGAGATGTGGG
AATTGCACACGGGAAAGCTGTGTGGTTTCCTTTTACCTTTCAGCTGACCATGAACTCCTGAGCCCGACCAACTACCACTTCTTGTCCTCA
CCGAAGGAGGCCGTGGGGCTCTGCAAGGCGCAGATCACTGCCATCATCTCTCAGCAAGGTGACATATTTGTTTTTGACCTGGAGACCTCA
GCTGTCGCTCCCTTTGTTTGGTTGGATGTAGGAAGCATCCCAGGGAGATTTAGTGACAATGGTTTCCTCATGACTGAGAAGACACGAACT
ATATTATTTTACCCTTGGGAGCCCACCAGCAAGAATGAGTTGGAGCAATCTTTTCATGTGACCTCCTTAACAGATATTTACTGAAGGAAT

>In-frame_ENST00000349311_ENST00000505239_TCGA-25-1632-01A_UBE2D3_chr4_103722611_-_MANBA_chr4_103611928_length(amino acids)=756AA_start in transcript=243_stop in transcript=2513
MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR
SQWSPALTISKDKSAQEWNLEIESTFDVVSSKPVGGQVIVAIPKLQTQQTYSIELQPGKRIVELFVNISKNITVETWWPHGHGNQTGYNM
TVLFELDGGLNIEKSAKVYFRTVELIEEPIKGSPGLSFYFKINGFPIFLKGSNWIPADSFQDRVTSELLRLLLQSVVDANMNTLRVWGGG
IYEQDEFYELCDELGIMVWQDFMFACALYPTDQGFLDSVTAEVAYQIKRLKSHPSIIIWSGNNENEEALMMNWYHISFTDRPIYIKDYVT
LYVKNIRELVLAGDKSRPFITSSPTNGAETVAEAWVSQNPNSNYFGDVHFYDYISDCWNWKVFPKARFASEYGYQSWPSFSTLEKVSSTE
DWSFNSKFSLHRQHHEGGNKQMLYQAGLHFKLPQSTDPLRTFKDTIYLTQVMQAQCVKTETEFYRRSRSEIVDQQGHTMGALYWQLNDIW
QAPSWASLEYGGKWKMLHYFAQNFFAPLLPVGFENENTFYIYGVSDLHSDYSMTLSVRVHTWSSLEPVCSRVTERFVMKGGEAVCLYEEP
VSELLRRCGNCTRESCVVSFYLSADHELLSPTNYHFLSSPKEAVGLCKAQITAIISQQGDIFVFDLETSAVAPFVWLDVGSIPGRFSDNG

--------------------------------------------------------------
>In-frame_ENST00000357194_ENST00000226578_TCGA-25-1632-01A_UBE2D3_chr4_103722611_-_MANBA_chr4_103611928_length(transcript)=2593nt_BP=462nt
CGCGGCGGACTGCCGAGGCGCGGGAACTGGCGGGTAGCGAGGCCCTCCTCGGAATCTCGTGTGAAGGTGGCCCTCCTCTTGGGCCTTTAA
CGTCTGTAGATGCTGGAGACCAGCAGAAAGGATACTGTGTGCGATGAGATAAGCATGTGAGAATGCTTTCTAACCGAAAGTGCCTTTCAA
AAGAACTTAGTGATTTGGCCCGTGACCCTCCAGCACAATGTTCTGCAGGTCCAGTTGGGGATGATATGTTTCATTGGCAAGCCACAATTA
TGGGACCTAATGACAGCCCATATCAAGGCGGTGTATTCTTTTTGACAATTCATTTTCCTACAGACTACCCCTTCAAACCACCTAAGGTTG
CATTTACAACAAGAATTTATCATCCAAATATTAACAGTAATGGCAGCATTTGTCTCGATATTCTAAGATCACAGTGGTCGCCTGCTTTAA
CAATTTCTAAAGATAAGAGTGCCCAGGAGTGGAATCTGGAAATAGAGTCTACATTTGATGTTGTCAGCTCAAAGCCAGTTGGTGGTCAAG
TGATCGTAGCCATCCCTAAGTTGCAAACACAACAGACATACAGCATTGAACTTCAACCTGGGAAAAGGATTGTTGAGCTATTTGTGAACA
TTAGCAAGAATATTACTGTAGAAACTTGGTGGCCTCATGGACATGGAAACCAGACTGGGTACAACATGACTGTTCTTTTTGAACTGGATG
GAGGCTTAAATATTGAAAAATCAGCTAAGGTTTATTTTAGGACAGTGGAACTTATAGAAGAGCCTATAAAAGGGTCTCCTGGTTTGAGTT
TCTATTTCAAAATTAATGGATTTCCCATATTTCTAAAAGGCTCAAACTGGATCCCAGCAGATTCATTCCAGGACCGAGTAACCTCTGAGT
TGTTACGGCTCCTTTTACAGTCTGTTGTGGATGCTAATATGAATACTCTTCGGGTTTGGGGAGGAGGAATTTATGAGCAGGATGAATTCT
ATGAACTCTGTGATGAACTAGGAATAATGGTATGGCAGGATTTTATGTTTGCCTGTGCCCTTTATCCAACTGATCAGGGCTTCCTGGATT
CAGTGACAGCAGAAGTTGCCTACCAGATCAAGAGACTGAAATCTCATCCTTCTATCATCATATGGAGTGGCAATAATGAAAATGAGGAGG
CGCTGATGATGAATTGGTATCATATCAGTTTCACTGACCGGCCAATCTACATCAAGGACTATGTGACACTCTATGTGAAAAACATCAGAG
AGCTCGTACTGGCAGGAGACAAGAGTCGTCCTTTTATTACGTCCAGTCCTACAAATGGGGCTGAAACTGTTGCAGAAGCCTGGGTCTCTC
AAAACCCTAATAGCAATTATTTTGGTGATGTACATTTTTATGACTATATCAGTGATTGCTGGAACTGGAAAGTTTTCCCAAAAGCTCGAT
TTGCATCTGAATATGGATATCAGTCCTGGCCGTCCTTCAGTACATTAGAAAAGGTCTCGTCTACAGAGGACTGGTCTTTCAATAGCAAGT
TTTCACTTCATCGACAACATCACGAAGGTGGTAACAAACAAATGCTTTATCAGGCTGGACTTCATTTCAAACTCCCCCAAAGCACAGATC
CATTACGCACATTTAAAGATACCATCTACCTTACTCAGGTGATGCAGGCCCAGTGTGTCAAAACAGAAACTGAATTCTACCGCCGTAGTC
GCAGCGAGATAGTGGATCAGCAAGGGCACACGATGGGGGCACTTTATTGGCAGTTGAATGACATCTGGCAAGCTCCTTCCTGGGCTTCTC
TTGAGTACGGAGGAAAGTGGAAAATGCTTCATTACTTTGCTCAGAATTTCTTTGCTCCACTGTTGCCAGTAGGCTTTGAGAATGAAAACA
CGTTCTATATCTATGGTGTGTCAGATCTTCACTCGGATTATTCGATGACACTCAGTGTGAGAGTCCATACATGGAGCTCCCTGGAGCCCG
TGTGCTCTCGTGTGACTGAACGTTTTGTGATGAAAGGAGGAGAGGCTGTCTGCCTTTATGAGGAGCCAGTGTCTGAATTGCTGAGGAGAT
GTGGGAATTGCACACGGGAAAGCTGTGTGGTTTCCTTTTACCTTTCAGCTGACCATGAACTCCTGAGCCCGACCAACTACCACTTCTTGT
CCTCACCGAAGGAGGCCGTGGGGCTCTGCAAGGCGCAGATCACTGCCATCATCTCTCAGCAAGGTGACATATTTGTTTTTGACCTGGAGA
CCTCAGCTGTCGCTCCCTTTGTTTGGTTGGATGTAGGAAGCATCCCAGGGAGATTTAGTGACAATGGTTTCCTCATGACTGAGAAGACAC
GAACTATATTATTTTACCCTTGGGAGCCCACCAGCAAGAATGAGTTGGAGCAATCTTTTCATGTGACCTCCTTAACAGATATTTACTGAA
GGAATCTAGGTTGTATTTTCAGTGGACAATGGGAATAAAGCATTTCTAAAGCACCGACTGGAGAGGAAGGCAACAGAGACAAGGAGAGAA

>In-frame_ENST00000357194_ENST00000226578_TCGA-25-1632-01A_UBE2D3_chr4_103722611_-_MANBA_chr4_103611928_length(amino acids)=758AA_start in transcript=152_stop in transcript=2428
MLSNRKCLSKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDI
LRSQWSPALTISKDKSAQEWNLEIESTFDVVSSKPVGGQVIVAIPKLQTQQTYSIELQPGKRIVELFVNISKNITVETWWPHGHGNQTGY
NMTVLFELDGGLNIEKSAKVYFRTVELIEEPIKGSPGLSFYFKINGFPIFLKGSNWIPADSFQDRVTSELLRLLLQSVVDANMNTLRVWG
GGIYEQDEFYELCDELGIMVWQDFMFACALYPTDQGFLDSVTAEVAYQIKRLKSHPSIIIWSGNNENEEALMMNWYHISFTDRPIYIKDY
VTLYVKNIRELVLAGDKSRPFITSSPTNGAETVAEAWVSQNPNSNYFGDVHFYDYISDCWNWKVFPKARFASEYGYQSWPSFSTLEKVSS
TEDWSFNSKFSLHRQHHEGGNKQMLYQAGLHFKLPQSTDPLRTFKDTIYLTQVMQAQCVKTETEFYRRSRSEIVDQQGHTMGALYWQLND
IWQAPSWASLEYGGKWKMLHYFAQNFFAPLLPVGFENENTFYIYGVSDLHSDYSMTLSVRVHTWSSLEPVCSRVTERFVMKGGEAVCLYE
EPVSELLRRCGNCTRESCVVSFYLSADHELLSPTNYHFLSSPKEAVGLCKAQITAIISQQGDIFVFDLETSAVAPFVWLDVGSIPGRFSD

--------------------------------------------------------------
>In-frame_ENST00000357194_ENST00000505239_TCGA-25-1632-01A_UBE2D3_chr4_103722611_-_MANBA_chr4_103611928_length(transcript)=2498nt_BP=462nt
CGCGGCGGACTGCCGAGGCGCGGGAACTGGCGGGTAGCGAGGCCCTCCTCGGAATCTCGTGTGAAGGTGGCCCTCCTCTTGGGCCTTTAA
CGTCTGTAGATGCTGGAGACCAGCAGAAAGGATACTGTGTGCGATGAGATAAGCATGTGAGAATGCTTTCTAACCGAAAGTGCCTTTCAA
AAGAACTTAGTGATTTGGCCCGTGACCCTCCAGCACAATGTTCTGCAGGTCCAGTTGGGGATGATATGTTTCATTGGCAAGCCACAATTA
TGGGACCTAATGACAGCCCATATCAAGGCGGTGTATTCTTTTTGACAATTCATTTTCCTACAGACTACCCCTTCAAACCACCTAAGGTTG
CATTTACAACAAGAATTTATCATCCAAATATTAACAGTAATGGCAGCATTTGTCTCGATATTCTAAGATCACAGTGGTCGCCTGCTTTAA
CAATTTCTAAAGATAAGAGTGCCCAGGAGTGGAATCTGGAAATAGAGTCTACATTTGATGTTGTCAGCTCAAAGCCAGTTGGTGGTCAAG
TGATCGTAGCCATCCCTAAGTTGCAAACACAACAGACATACAGCATTGAACTTCAACCTGGGAAAAGGATTGTTGAGCTATTTGTGAACA
TTAGCAAGAATATTACTGTAGAAACTTGGTGGCCTCATGGACATGGAAACCAGACTGGGTACAACATGACTGTTCTTTTTGAACTGGATG
GAGGCTTAAATATTGAAAAATCAGCTAAGGTTTATTTTAGGACAGTGGAACTTATAGAAGAGCCTATAAAAGGGTCTCCTGGTTTGAGTT
TCTATTTCAAAATTAATGGATTTCCCATATTTCTAAAAGGCTCAAACTGGATCCCAGCAGATTCATTCCAGGACCGAGTAACCTCTGAGT
TGTTACGGCTCCTTTTACAGTCTGTTGTGGATGCTAATATGAATACTCTTCGGGTTTGGGGAGGAGGAATTTATGAGCAGGATGAATTCT
ATGAACTCTGTGATGAACTAGGAATAATGGTATGGCAGGATTTTATGTTTGCCTGTGCCCTTTATCCAACTGATCAGGGCTTCCTGGATT
CAGTGACAGCAGAAGTTGCCTACCAGATCAAGAGACTGAAATCTCATCCTTCTATCATCATATGGAGTGGCAATAATGAAAATGAGGAGG
CGCTGATGATGAATTGGTATCATATCAGTTTCACTGACCGGCCAATCTACATCAAGGACTATGTGACACTCTATGTGAAAAACATCAGAG
AGCTCGTACTGGCAGGAGACAAGAGTCGTCCTTTTATTACGTCCAGTCCTACAAATGGGGCTGAAACTGTTGCAGAAGCCTGGGTCTCTC
AAAACCCTAATAGCAATTATTTTGGTGATGTACATTTTTATGACTATATCAGTGATTGCTGGAACTGGAAAGTTTTCCCAAAAGCTCGAT
TTGCATCTGAATATGGATATCAGTCCTGGCCGTCCTTCAGTACATTAGAAAAGGTCTCGTCTACAGAGGACTGGTCTTTCAATAGCAAGT
TTTCACTTCATCGACAACATCACGAAGGTGGTAACAAACAAATGCTTTATCAGGCTGGACTTCATTTCAAACTCCCCCAAAGCACAGATC
CATTACGCACATTTAAAGATACCATCTACCTTACTCAGGTGATGCAGGCCCAGTGTGTCAAAACAGAAACTGAATTCTACCGCCGTAGTC
GCAGCGAGATAGTGGATCAGCAAGGGCACACGATGGGGGCACTTTATTGGCAGTTGAATGACATCTGGCAAGCTCCTTCCTGGGCTTCTC
TTGAGTACGGAGGAAAGTGGAAAATGCTTCATTACTTTGCTCAGAATTTCTTTGCTCCACTGTTGCCAGTAGGCTTTGAGAATGAAAACA
CGTTCTATATCTATGGTGTGTCAGATCTTCACTCGGATTATTCGATGACACTCAGTGTGAGAGTCCATACATGGAGCTCCCTGGAGCCCG
TGTGCTCTCGTGTGACTGAACGTTTTGTGATGAAAGGAGGAGAGGCTGTCTGCCTTTATGAGGAGCCAGTGTCTGAATTGCTGAGGAGAT
GTGGGAATTGCACACGGGAAAGCTGTGTGGTTTCCTTTTACCTTTCAGCTGACCATGAACTCCTGAGCCCGACCAACTACCACTTCTTGT
CCTCACCGAAGGAGGCCGTGGGGCTCTGCAAGGCGCAGATCACTGCCATCATCTCTCAGCAAGGTGACATATTTGTTTTTGACCTGGAGA
CCTCAGCTGTCGCTCCCTTTGTTTGGTTGGATGTAGGAAGCATCCCAGGGAGATTTAGTGACAATGGTTTCCTCATGACTGAGAAGACAC
GAACTATATTATTTTACCCTTGGGAGCCCACCAGCAAGAATGAGTTGGAGCAATCTTTTCATGTGACCTCCTTAACAGATATTTACTGAA

>In-frame_ENST00000357194_ENST00000505239_TCGA-25-1632-01A_UBE2D3_chr4_103722611_-_MANBA_chr4_103611928_length(amino acids)=758AA_start in transcript=152_stop in transcript=2428
MLSNRKCLSKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDI
LRSQWSPALTISKDKSAQEWNLEIESTFDVVSSKPVGGQVIVAIPKLQTQQTYSIELQPGKRIVELFVNISKNITVETWWPHGHGNQTGY
NMTVLFELDGGLNIEKSAKVYFRTVELIEEPIKGSPGLSFYFKINGFPIFLKGSNWIPADSFQDRVTSELLRLLLQSVVDANMNTLRVWG
GGIYEQDEFYELCDELGIMVWQDFMFACALYPTDQGFLDSVTAEVAYQIKRLKSHPSIIIWSGNNENEEALMMNWYHISFTDRPIYIKDY
VTLYVKNIRELVLAGDKSRPFITSSPTNGAETVAEAWVSQNPNSNYFGDVHFYDYISDCWNWKVFPKARFASEYGYQSWPSFSTLEKVSS
TEDWSFNSKFSLHRQHHEGGNKQMLYQAGLHFKLPQSTDPLRTFKDTIYLTQVMQAQCVKTETEFYRRSRSEIVDQQGHTMGALYWQLND
IWQAPSWASLEYGGKWKMLHYFAQNFFAPLLPVGFENENTFYIYGVSDLHSDYSMTLSVRVHTWSSLEPVCSRVTERFVMKGGEAVCLYE
EPVSELLRRCGNCTRESCVVSFYLSADHELLSPTNYHFLSSPKEAVGLCKAQITAIISQQGDIFVFDLETSAVAPFVWLDVGSIPGRFSD

--------------------------------------------------------------

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Fusion Gene PPI Analysis for UBE2D3-MANBA


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for UBE2D3-MANBA


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for UBE2D3-MANBA


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneMANBAC4048196beta-Mannosidosis8CTD_human;GENOMICS_ENGLAND;UNIPROT
TgeneMANBAC2931893Lysosomal beta-mannosidase deficiency1ORPHANET