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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:VPS13B-AHI1 (FusionGDB2 ID:97587)

Fusion Gene Summary for VPS13B-AHI1

check button Fusion gene summary
Fusion gene informationFusion gene name: VPS13B-AHI1
Fusion gene ID: 97587
HgeneTgene
Gene symbol

VPS13B

AHI1

Gene ID

157680

54806

Gene namevacuolar protein sorting 13 homolog BAbelson helper integration site 1
SynonymsCHS1|COH1AHI-1|JBTS3|ORF1|dJ71N10.1
Cytomap

8q22.2

6q23.3

Type of geneprotein-codingprotein-coding
Descriptionvacuolar protein sorting-associated protein 13Bjouberinabelson helper integration site 1 protein homologcontatins SH3 and WD40 domains
Modification date2020031320200313
UniProtAcc.

Q8N157

Ensembl transtripts involved in fusion geneENST00000395996, ENST00000358544, 
ENST00000357162, ENST00000355155, 
ENST00000441350, ENST00000521932, 
ENST00000367800, ENST00000457866, 
ENST00000417892, ENST00000327035, 
ENST00000488690, ENST00000367798, 
ENST00000528103, ENST00000534469, 
ENST00000531527, 
Fusion gene scores* DoF score43 X 36 X 17=263169 X 10 X 7=630
# samples 5010
** MAII scorelog2(50/26316*10)=-5.71786831273266
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/630*10)=-2.65535182861255
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: VPS13B [Title/Abstract] AND AHI1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointVPS13B(100050794)-AHI1(135644462), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across VPS13B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across AHI1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-BH-A1F0-01AVPS13Bchr8

100050794

+AHI1chr6

135644462

-
ChimerDB4BRCATCGA-BH-A1F0-01AVPS13Bchr8

100050794

+AHI1chr6

135644462

-


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Fusion Gene ORF analysis for VPS13B-AHI1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000395996ENST00000367800VPS13Bchr8

100050794

+AHI1chr6

135644462

-
In-frameENST00000395996ENST00000457866VPS13Bchr8

100050794

+AHI1chr6

135644462

-
In-frameENST00000395996ENST00000417892VPS13Bchr8

100050794

+AHI1chr6

135644462

-
5CDS-intronENST00000395996ENST00000327035VPS13Bchr8

100050794

+AHI1chr6

135644462

-
5CDS-intronENST00000395996ENST00000488690VPS13Bchr8

100050794

+AHI1chr6

135644462

-
5CDS-intronENST00000395996ENST00000367798VPS13Bchr8

100050794

+AHI1chr6

135644462

-
5CDS-intronENST00000395996ENST00000528103VPS13Bchr8

100050794

+AHI1chr6

135644462

-
5CDS-intronENST00000395996ENST00000534469VPS13Bchr8

100050794

+AHI1chr6

135644462

-
5CDS-intronENST00000395996ENST00000531527VPS13Bchr8

100050794

+AHI1chr6

135644462

-
In-frameENST00000358544ENST00000367800VPS13Bchr8

100050794

+AHI1chr6

135644462

-
In-frameENST00000358544ENST00000457866VPS13Bchr8

100050794

+AHI1chr6

135644462

-
In-frameENST00000358544ENST00000417892VPS13Bchr8

100050794

+AHI1chr6

135644462

-
5CDS-intronENST00000358544ENST00000327035VPS13Bchr8

100050794

+AHI1chr6

135644462

-
5CDS-intronENST00000358544ENST00000488690VPS13Bchr8

100050794

+AHI1chr6

135644462

-
5CDS-intronENST00000358544ENST00000367798VPS13Bchr8

100050794

+AHI1chr6

135644462

-
5CDS-intronENST00000358544ENST00000528103VPS13Bchr8

100050794

+AHI1chr6

135644462

-
5CDS-intronENST00000358544ENST00000534469VPS13Bchr8

100050794

+AHI1chr6

135644462

-
5CDS-intronENST00000358544ENST00000531527VPS13Bchr8

100050794

+AHI1chr6

135644462

-
In-frameENST00000357162ENST00000367800VPS13Bchr8

100050794

+AHI1chr6

135644462

-
In-frameENST00000357162ENST00000457866VPS13Bchr8

100050794

+AHI1chr6

135644462

-
In-frameENST00000357162ENST00000417892VPS13Bchr8

100050794

+AHI1chr6

135644462

-
5CDS-intronENST00000357162ENST00000327035VPS13Bchr8

100050794

+AHI1chr6

135644462

-
5CDS-intronENST00000357162ENST00000488690VPS13Bchr8

100050794

+AHI1chr6

135644462

-
5CDS-intronENST00000357162ENST00000367798VPS13Bchr8

100050794

+AHI1chr6

135644462

-
5CDS-intronENST00000357162ENST00000528103VPS13Bchr8

100050794

+AHI1chr6

135644462

-
5CDS-intronENST00000357162ENST00000534469VPS13Bchr8

100050794

+AHI1chr6

135644462

-
5CDS-intronENST00000357162ENST00000531527VPS13Bchr8

100050794

+AHI1chr6

135644462

-
In-frameENST00000355155ENST00000367800VPS13Bchr8

100050794

+AHI1chr6

135644462

-
In-frameENST00000355155ENST00000457866VPS13Bchr8

100050794

+AHI1chr6

135644462

-
In-frameENST00000355155ENST00000417892VPS13Bchr8

100050794

+AHI1chr6

135644462

-
5CDS-intronENST00000355155ENST00000327035VPS13Bchr8

100050794

+AHI1chr6

135644462

-
5CDS-intronENST00000355155ENST00000488690VPS13Bchr8

100050794

+AHI1chr6

135644462

-
5CDS-intronENST00000355155ENST00000367798VPS13Bchr8

100050794

+AHI1chr6

135644462

-
5CDS-intronENST00000355155ENST00000528103VPS13Bchr8

100050794

+AHI1chr6

135644462

-
5CDS-intronENST00000355155ENST00000534469VPS13Bchr8

100050794

+AHI1chr6

135644462

-
5CDS-intronENST00000355155ENST00000531527VPS13Bchr8

100050794

+AHI1chr6

135644462

-
In-frameENST00000441350ENST00000367800VPS13Bchr8

100050794

+AHI1chr6

135644462

-
In-frameENST00000441350ENST00000457866VPS13Bchr8

100050794

+AHI1chr6

135644462

-
In-frameENST00000441350ENST00000417892VPS13Bchr8

100050794

+AHI1chr6

135644462

-
5CDS-intronENST00000441350ENST00000327035VPS13Bchr8

100050794

+AHI1chr6

135644462

-
5CDS-intronENST00000441350ENST00000488690VPS13Bchr8

100050794

+AHI1chr6

135644462

-
5CDS-intronENST00000441350ENST00000367798VPS13Bchr8

100050794

+AHI1chr6

135644462

-
5CDS-intronENST00000441350ENST00000528103VPS13Bchr8

100050794

+AHI1chr6

135644462

-
5CDS-intronENST00000441350ENST00000534469VPS13Bchr8

100050794

+AHI1chr6

135644462

-
5CDS-intronENST00000441350ENST00000531527VPS13Bchr8

100050794

+AHI1chr6

135644462

-
intron-3CDSENST00000521932ENST00000367800VPS13Bchr8

100050794

+AHI1chr6

135644462

-
intron-3CDSENST00000521932ENST00000457866VPS13Bchr8

100050794

+AHI1chr6

135644462

-
intron-3CDSENST00000521932ENST00000417892VPS13Bchr8

100050794

+AHI1chr6

135644462

-
intron-intronENST00000521932ENST00000327035VPS13Bchr8

100050794

+AHI1chr6

135644462

-
intron-intronENST00000521932ENST00000488690VPS13Bchr8

100050794

+AHI1chr6

135644462

-
intron-intronENST00000521932ENST00000367798VPS13Bchr8

100050794

+AHI1chr6

135644462

-
intron-intronENST00000521932ENST00000528103VPS13Bchr8

100050794

+AHI1chr6

135644462

-
intron-intronENST00000521932ENST00000534469VPS13Bchr8

100050794

+AHI1chr6

135644462

-
intron-intronENST00000521932ENST00000531527VPS13Bchr8

100050794

+AHI1chr6

135644462

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000395996VPS13Bchr8100050794+ENST00000367800AHI1chr6135644462-2941402111827238
ENST00000395996VPS13Bchr8100050794+ENST00000457866AHI1chr6135644462-2487402111827238
ENST00000395996VPS13Bchr8100050794+ENST00000417892AHI1chr6135644462-1965402111671186
ENST00000358544VPS13Bchr8100050794+ENST00000367800AHI1chr6135644462-2941402111827238
ENST00000358544VPS13Bchr8100050794+ENST00000457866AHI1chr6135644462-2487402111827238
ENST00000358544VPS13Bchr8100050794+ENST00000417892AHI1chr6135644462-1965402111671186
ENST00000357162VPS13Bchr8100050794+ENST00000367800AHI1chr6135644462-2941402111827238
ENST00000357162VPS13Bchr8100050794+ENST00000457866AHI1chr6135644462-2487402111827238
ENST00000357162VPS13Bchr8100050794+ENST00000417892AHI1chr6135644462-1965402111671186
ENST00000355155VPS13Bchr8100050794+ENST00000367800AHI1chr6135644462-2941402111827238
ENST00000355155VPS13Bchr8100050794+ENST00000457866AHI1chr6135644462-2487402111827238
ENST00000355155VPS13Bchr8100050794+ENST00000417892AHI1chr6135644462-1965402111671186
ENST00000441350VPS13Bchr8100050794+ENST00000367800AHI1chr6135644462-2933394103819238
ENST00000441350VPS13Bchr8100050794+ENST00000457866AHI1chr6135644462-2479394103819238
ENST00000441350VPS13Bchr8100050794+ENST00000417892AHI1chr6135644462-1957394103663186

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000395996ENST00000367800VPS13Bchr8100050794+AHI1chr6135644462-0.000854930.99914503
ENST00000395996ENST00000457866VPS13Bchr8100050794+AHI1chr6135644462-0.0009909140.999009
ENST00000395996ENST00000417892VPS13Bchr8100050794+AHI1chr6135644462-0.0029926040.9970074
ENST00000358544ENST00000367800VPS13Bchr8100050794+AHI1chr6135644462-0.000854930.99914503
ENST00000358544ENST00000457866VPS13Bchr8100050794+AHI1chr6135644462-0.0009909140.999009
ENST00000358544ENST00000417892VPS13Bchr8100050794+AHI1chr6135644462-0.0029926040.9970074
ENST00000357162ENST00000367800VPS13Bchr8100050794+AHI1chr6135644462-0.000854930.99914503
ENST00000357162ENST00000457866VPS13Bchr8100050794+AHI1chr6135644462-0.0009909140.999009
ENST00000357162ENST00000417892VPS13Bchr8100050794+AHI1chr6135644462-0.0029926040.9970074
ENST00000355155ENST00000367800VPS13Bchr8100050794+AHI1chr6135644462-0.000854930.99914503
ENST00000355155ENST00000457866VPS13Bchr8100050794+AHI1chr6135644462-0.0009909140.999009
ENST00000355155ENST00000417892VPS13Bchr8100050794+AHI1chr6135644462-0.0029926040.9970074
ENST00000441350ENST00000367800VPS13Bchr8100050794+AHI1chr6135644462-0.0007272650.99927276
ENST00000441350ENST00000457866VPS13Bchr8100050794+AHI1chr6135644462-0.0008141820.99918586
ENST00000441350ENST00000417892VPS13Bchr8100050794+AHI1chr6135644462-0.0030949040.996905

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Fusion Genomic Features for VPS13B-AHI1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for VPS13B-AHI1


check button Go to

FGviewer for the breakpoints of chr8:100050794-chr6:135644462

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.AHI1

Q8N157

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Involved in vesicle trafficking and required for ciliogenesis, formation of primary non-motile cilium, and recruitment of RAB8A to the basal body of primary cilium. Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in neuronal differentiation. As a positive modulator of classical Wnt signaling, may play a crucial role in ciliary signaling during cerebellum embryonic development (PubMed:21623382). {ECO:0000250|UniProtKB:Q8K3E5, ECO:0000269|PubMed:21623382}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneAHI1chr8:100050794chr6:135644462ENST0000032703502313_4501054.0Coiled coilOntology_term=ECO:0000255
TgeneAHI1chr8:100050794chr6:135644462ENST00000327035023234_23901054.0Compositional biasNote=Poly-Lys
TgeneAHI1chr8:100050794chr6:135644462ENST000003270350231051_111101054.0DomainSH3
TgeneAHI1chr8:100050794chr6:135644462ENST00000327035023607_64901054.0RepeatNote=WD 1
TgeneAHI1chr8:100050794chr6:135644462ENST00000327035023652_69101054.0RepeatNote=WD 2
TgeneAHI1chr8:100050794chr6:135644462ENST00000327035023695_73501054.0RepeatNote=WD 3
TgeneAHI1chr8:100050794chr6:135644462ENST00000327035023742_78101054.0RepeatNote=WD 4
TgeneAHI1chr8:100050794chr6:135644462ENST00000327035023797_83701054.0RepeatNote=WD 5
TgeneAHI1chr8:100050794chr6:135644462ENST00000327035023841_88001054.0RepeatNote=WD 6
TgeneAHI1chr8:100050794chr6:135644462ENST00000327035023885_92601054.0RepeatNote=WD 7

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneAHI1chr8:100050794chr6:135644462ENST00000367800212713_451055.01197.0Coiled coilOntology_term=ECO:0000255
TgeneAHI1chr8:100050794chr6:135644462ENST00000457866222813_451055.01197.0Coiled coilOntology_term=ECO:0000255
TgeneAHI1chr8:100050794chr6:135644462ENST000003678002127234_2391055.01197.0Compositional biasNote=Poly-Lys
TgeneAHI1chr8:100050794chr6:135644462ENST000004578662228234_2391055.01197.0Compositional biasNote=Poly-Lys
TgeneAHI1chr8:100050794chr6:135644462ENST0000036780021271051_11111055.01197.0DomainSH3
TgeneAHI1chr8:100050794chr6:135644462ENST0000045786622281051_11111055.01197.0DomainSH3
TgeneAHI1chr8:100050794chr6:135644462ENST000003678002127607_6491055.01197.0RepeatNote=WD 1
TgeneAHI1chr8:100050794chr6:135644462ENST000003678002127652_6911055.01197.0RepeatNote=WD 2
TgeneAHI1chr8:100050794chr6:135644462ENST000003678002127695_7351055.01197.0RepeatNote=WD 3
TgeneAHI1chr8:100050794chr6:135644462ENST000003678002127742_7811055.01197.0RepeatNote=WD 4
TgeneAHI1chr8:100050794chr6:135644462ENST000003678002127797_8371055.01197.0RepeatNote=WD 5
TgeneAHI1chr8:100050794chr6:135644462ENST000003678002127841_8801055.01197.0RepeatNote=WD 6
TgeneAHI1chr8:100050794chr6:135644462ENST000003678002127885_9261055.01197.0RepeatNote=WD 7
TgeneAHI1chr8:100050794chr6:135644462ENST000004578662228607_6491055.01197.0RepeatNote=WD 1
TgeneAHI1chr8:100050794chr6:135644462ENST000004578662228652_6911055.01197.0RepeatNote=WD 2
TgeneAHI1chr8:100050794chr6:135644462ENST000004578662228695_7351055.01197.0RepeatNote=WD 3
TgeneAHI1chr8:100050794chr6:135644462ENST000004578662228742_7811055.01197.0RepeatNote=WD 4
TgeneAHI1chr8:100050794chr6:135644462ENST000004578662228797_8371055.01197.0RepeatNote=WD 5
TgeneAHI1chr8:100050794chr6:135644462ENST000004578662228841_8801055.01197.0RepeatNote=WD 6
TgeneAHI1chr8:100050794chr6:135644462ENST000004578662228885_9261055.01197.0RepeatNote=WD 7


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Fusion Gene Sequence for VPS13B-AHI1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000395996_ENST00000367800_TCGA-BH-A1F0-01A_VPS13B_chr8_100050794_+_AHI1_chr6_135644462_length(transcript)=2941nt_BP=402nt
GGCGCGGTACAGGAGCAGCACTGCCGGCGGGGGCGGGTGCCAGGGACTTGGAGGTGGAGGGGACGCGGCGGTACTCTGGCGTCTTCCGAC
TTCGACTCCTTACCTTAAAAGATGCTGGAGTCATATGTAACTCCAATTTTAATGAGCTATGTGAATCGCTACATCAAGAACTTAAAGCCG
TCGGATCTACAGCTTTCACTATGGGGTGGAGACGTGGTACTCAGCAAGCTCGAGTTAAAGTTGGATGTGCTGGAACAGGAACTGAAATTA
CCATTCACTTTTTTAAGTGGACATATTCATGAATTGAGGATTCATGTACCATGGACAAAACTGGGTTCAGAACCAGTGGTAATTACCATC
AATACTATGGAATGCATTTTGAAACTTAAGGATGGGATACAGGTAGTGGCTCTTTATGACTACACAGCGAATCGATCAGATGAACTAACC
ATCCATCGCGGAGACATTATCCGAGTGTTTTTCAAAGATAATGAAGACTGGTGGTATGGCAGCATAGGAAAGGGACAGGAAGGTTATTTT
CCAGCTAATCATGTGGCTAGTGAAACACTGTATCAAGAACTGCCTCCTGAGATAAAGGAGCGATCCCCTCCTTTAAGCCCTGAGGAAAAA
ACTAAAATAGAAAAATCTCCAGCTCCTCAAAAGCAATCAATCAATAAGAACAAGTCCCAGGACTTCAGACTAGGCTCAGAATCTATGACA
CATTCTGAAATGAGAAAAGAACAGAGCCATGAGGACCAAGGACACATAATGGATACACGGATGAGGAAGAACAAGCAAGCAGGCAGAAAA
GTCACTCTAATAGAGTAAAGAATTGAAGAAAAGTTAAGAGCTGCCGAAATGCACAGAGGTGAAAATGACAAACCAAATGGAATTTCTCTT
CAGAGTTCAGAATTTTCAGATACTAAGGAGGAAGAAAGGATCCACTACTTCTTGTTCTTATGAATGACTCTAGAAAAATCAGAATCAAGT
TGTGGGTGGAAAAATCAACGTGGCCTTTGAGTTCAGTTGTTATAAACCATTGTGACTATTGTTGGTCAAAGTATTGGTACTTATATTGTT
AGTAATTGCATCATAATTACATTACCAGTGTTGGAAAACTAATGAAGAAAACACTGTAATTGCTACTCAGCAAATGTGAATAAAAGGTGT
TTGCGTTATTAGGATGTCTGTTAAGTAATCATTTAATATTATTATATTGGTAATGGTTGTATGTGTGATGCTATGCCCAGAATATGAAGT
ATCTGTTTTTGAAATTCACTTTATTTAAAAGATAAGCAGCTGACTGGGCACGGTGCCTCATGCCTGTAATCCTAGCACCTTGGGAGGCTG
AGGCAGGTGGATCACCTAAGGTCAGGAGTTCAACAACACCAGCCTGACCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATCA
GCCGGGTCTCATGGCAGGCACCTGTAATCCCATCTACTGAGGCAGGAGAATTGCTTGACCCAGGAGGCAGAGGTTGCAGTGAGCCAAGAT
CACGCCATTGCACTCCAGCCTGGGGGACAGAGCAAGACTCTATCTCCAAAAAACAAAAAAGATAAGCAGCTTTAGAATATGGCGCATTCA
AAACAGTCTCAGTAACAAAGACATTAAAAGAAAACAATTTACTTTCTAATTAAAATTTTGTGTTTCTTAAGATCAAATCATATAGGTAAC
TTCATAGACCTAAATTAAAAGTGATTTTTGGCTGGACTGGCAACAATGTTCCCAATGTCTTTACTTTTTAAAAAAGGCTTTTCATATTTA
AGCACATACCTATTTTGTAGACTTACATTGTTTAATATTTATTTTAATCTTAATATTTTTACATTATTATATTGCATTATTTATTTTTTC
TAAGTTCCAGAATAATAGTGTCATTATTATAGACTATATGTTTTGAAGTTTGATATTATAATGGGATATTCATTTTTTGTTCTTTTCTTG
ACTCCTTTCTCAAGTGTGTGATAAGGTCTGCTGATAAAATATTTAACCCCAAGAAAGTGAAAACTAATATAAAATTAGAAAGACCTATCC
AAATTAGACAGTCAATTCCATTAAAATAAGAAGTGAGAAAAACAATGTTGGGCATTGAGGTGTAAATTTTGCCCAGATGTATACCCAGTG
TGAAATATCTTCTAATAAAAATATATTTGGCTCTTATCCCTGCACATGTAGAGGCATAAAAATTGGTAAACATGTCCCGCTGTGTAGAAC
TTTAAAAAAAAGGCATTTTTGAAAGTGTTGAGTGGCACTGATAACTGGTGAAGCCTACAGCCATCCGCCCAAAAGTCTGTTCTGATGGCA
CTGAGTTTTCATTGTTCTGGATGTATAAGTCTGTGTGTCAGGTACAGCTGGGCCCAGCCAGCTTGAGTCACTCTTGTACAAGCTTGTTTT
TTTCTGTCTTGTGAATGCACTTGATAATTTAAAAATAAAAATATCTGTTTCTCTGCAGTTTCAGCTAATAATTTTGAGATATGTGTTGAT
TTTCTGATTGAATCACCAAGAATTTCAACAAGTTTAGAAATAATTTAAGATGAATGAAAAATATGTCAGGGGGAGCTAAGCATTTGCTAA
GCTCTTGATGTTTATATGAAAAATAAAGGGTTGTTTTTATATTGCAACTACTAAAGAGAAAAATAGCAGTTGAAGCAAACACCAGGAAAA
TTTGGCTCTACTGAAAGCCCAGTCCTTTTCCCCTTTGTCTCGCTGACAAAGTAAGACTAGGGTTATGTTCATGAATAGATTAATAAAAGA
TGTTTCTTTACCACACAATCTGAGATGAGATGGGGTGGGGGAGATCATGACAGTGCCCTCCAAGCAATAGATCCAGCTGATAATCAAGCA

>In-frame_ENST00000395996_ENST00000367800_TCGA-BH-A1F0-01A_VPS13B_chr8_100050794_+_AHI1_chr6_135644462_length(amino acids)=238AA_start in transcript=111_stop in transcript=827
MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSGHIHELRIHVPWTKLGSEPVVITINTMECIL
KLKDGIQVVALYDYTANRSDELTIHRGDIIRVFFKDNEDWWYGSIGKGQEGYFPANHVASETLYQELPPEIKERSPPLSPEEKTKIEKSP

--------------------------------------------------------------
>In-frame_ENST00000395996_ENST00000457866_TCGA-BH-A1F0-01A_VPS13B_chr8_100050794_+_AHI1_chr6_135644462_length(transcript)=2487nt_BP=402nt
GGCGCGGTACAGGAGCAGCACTGCCGGCGGGGGCGGGTGCCAGGGACTTGGAGGTGGAGGGGACGCGGCGGTACTCTGGCGTCTTCCGAC
TTCGACTCCTTACCTTAAAAGATGCTGGAGTCATATGTAACTCCAATTTTAATGAGCTATGTGAATCGCTACATCAAGAACTTAAAGCCG
TCGGATCTACAGCTTTCACTATGGGGTGGAGACGTGGTACTCAGCAAGCTCGAGTTAAAGTTGGATGTGCTGGAACAGGAACTGAAATTA
CCATTCACTTTTTTAAGTGGACATATTCATGAATTGAGGATTCATGTACCATGGACAAAACTGGGTTCAGAACCAGTGGTAATTACCATC
AATACTATGGAATGCATTTTGAAACTTAAGGATGGGATACAGGTAGTGGCTCTTTATGACTACACAGCGAATCGATCAGATGAACTAACC
ATCCATCGCGGAGACATTATCCGAGTGTTTTTCAAAGATAATGAAGACTGGTGGTATGGCAGCATAGGAAAGGGACAGGAAGGTTATTTT
CCAGCTAATCATGTGGCTAGTGAAACACTGTATCAAGAACTGCCTCCTGAGATAAAGGAGCGATCCCCTCCTTTAAGCCCTGAGGAAAAA
ACTAAAATAGAAAAATCTCCAGCTCCTCAAAAGCAATCAATCAATAAGAACAAGTCCCAGGACTTCAGACTAGGCTCAGAATCTATGACA
CATTCTGAAATGAGAAAAGAACAGAGCCATGAGGACCAAGGACACATAATGGATACACGGATGAGGAAGAACAAGCAAGCAGGCAGAAAA
GTCACTCTAATAGAGTAAAGAATTGAAGAAAAGTTAAGAGCTGCCGAAATGCACAGAGGTGAAAATGACAAACCAAATGGAATTTCTCTT
CAGAGTTCAGAATTTTCAGATACTAAGGAGGAAGAAAGGATCCACTACTTCTTGTTCTTATGAATGACTCTAGAAAAATCAGAATCAAGT
TGTGGGTGGAAAAATCAACGTGGCCTTTGAGTTCAGTTGTTATAAACCATTGTGACTATTGTTGGTCAAAGTATTGGTACTTATATTGTT
AGTAATTGCATCATAATTACATTACCAGTGTTGGAAAACTAATGAAGAAAACACTGTAATTGCTACTCAGCAAATGTGAATAAAAGGTGT
TTGCGTTATTAGGATGTCTGTTAAGTAATCATTTAATATTATTATATTGGTAATGGTTGTATGTGTGATGCTATGCCCAGAATATGAAGT
ATCTGTTTTTGAAATTCACTTTATTTAAAAGATAAGCAGCTGACTGGGCACGGTGCCTCATGCCTGTAATCCTAGCACCTTGGGAGGCTG
AGGCAGGTGGATCACCTAAGGTCAGGAGTTCAACAACACCAGCCTGACCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATCA
GCCGGGTCTCATGGCAGGCACCTGTAATCCCATCTACTGAGGCAGGAGAATTGCTTGACCCAGGAGGCAGAGGTTGCAGTGAGCCAAGAT
CACGCCATTGCACTCCAGCCTGGGGGACAGAGCAAGACTCTATCTCCAAAAAACAAAAAAGATAAGCAGCTTTAGAATATGGCGCATTCA
AAACAGTCTCAGTAACAAAGACATTAAAAGAAAACAATTTACTTTCTAATTAAAATTTTGTGTTTCTTAAGATCAAATCATATAGGTAAC
TTCATAGACCTAAATTAAAAGTGATTTTTGGCTGGACTGGCAACAATGTTCCCAATGTCTTTACTTTTTAAAAAAGGCTTTTCATATTTA
AGCACATACCTATTTTGTAGACTTACATTGTTTAATATTTATTTTAATCTTAATATTTTTACATTATTATATTGCATTATTTATTTTTTC
TAAGTTCCAGAATAATAGTGTCATTATTATAGACTATATGTTTTGAAGTTTGATATTATAATGGGATATTCATTTTTTGTTCTTTTCTTG
ACTCCTTTCTCAAGTGTGTGATAAGGTCTGCTGATAAAATATTTAACCCCAAGAAAGTGAAAACTAATATAAAATTAGAAAGACCTATCC
AAATTAGACAGTCAATTCCATTAAAATAAGAAGTGAGAAAAACAATGTTGGGCATTGAGGTGTAAATTTTGCCCAGATGTATACCCAGTG
TGAAATATCTTCTAATAAAAATATATTTGGCTCTTATCCCTGCACATGTAGAGGCATAAAAATTGGTAAACATGTCCCGCTGTGTAGAAC
TTTAAAAAAAAGGCATTTTTGAAAGTGTTGAGTGGCACTGATAACTGGTGAAGCCTACAGCCATCCGCCCAAAAGTCTGTTCTGATGGCA
CTGAGTTTTCATTGTTCTGGATGTATAAGTCTGTGTGTCAGGTACAGCTGGGCCCAGCCAGCTTGAGTCACTCTTGTACAAGCTTGTTTT

>In-frame_ENST00000395996_ENST00000457866_TCGA-BH-A1F0-01A_VPS13B_chr8_100050794_+_AHI1_chr6_135644462_length(amino acids)=238AA_start in transcript=111_stop in transcript=827
MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSGHIHELRIHVPWTKLGSEPVVITINTMECIL
KLKDGIQVVALYDYTANRSDELTIHRGDIIRVFFKDNEDWWYGSIGKGQEGYFPANHVASETLYQELPPEIKERSPPLSPEEKTKIEKSP

--------------------------------------------------------------
>In-frame_ENST00000395996_ENST00000417892_TCGA-BH-A1F0-01A_VPS13B_chr8_100050794_+_AHI1_chr6_135644462_length(transcript)=1965nt_BP=402nt
GGCGCGGTACAGGAGCAGCACTGCCGGCGGGGGCGGGTGCCAGGGACTTGGAGGTGGAGGGGACGCGGCGGTACTCTGGCGTCTTCCGAC
TTCGACTCCTTACCTTAAAAGATGCTGGAGTCATATGTAACTCCAATTTTAATGAGCTATGTGAATCGCTACATCAAGAACTTAAAGCCG
TCGGATCTACAGCTTTCACTATGGGGTGGAGACGTGGTACTCAGCAAGCTCGAGTTAAAGTTGGATGTGCTGGAACAGGAACTGAAATTA
CCATTCACTTTTTTAAGTGGACATATTCATGAATTGAGGATTCATGTACCATGGACAAAACTGGGTTCAGAACCAGTGGTAATTACCATC
AATACTATGGAATGCATTTTGAAACTTAAGGATGGGATACAGGTAGTGGCTCTTTATGACTACACAGCGAATCGATCAGATGAACTAACC
ATCCATCGCGGAGACATTATCCGAGTGTTTTTCAAAGATAATGAAGACTGGTGGTATGGCAGCATAGGAAAGGGACAGGAAGGTTATTTT
CCAGCTAATCATGTGGCTAGTGAAACACTGTATCAAGAACTGCCTCCTGAGATAAAGGAGCGATCCCCTCCTTTAAGCCCTGAGGAAAAA
ACTAAAATAGAAAAATCTCCAGCTCCTCAAAAGGTAAAATAAAACAAAACAGCTCACAGAGACACCTCCTTCTTCCCCCTGCTTCTGCCT
CCATGAGTAACTACCTATATGACGTGCTGCTGCTGAGACCAAGGAATGAATAGTGCCAAATCTTGCTGAAGAATGATCTTGCAGAAATCT
GATTGTGAAGAAGGAAATCTAAAAAGGCCAAACAAGCTTCAGTAGAGATAACACCAGGAAAGCAGTTACTCAAACAAGACTGAAAGAGAA
GCAATCAATCAATAAGAACAAGTCCCAGGACTTCAGACTAGGCTCAGAATCTATGACACATTCTGAAATGAGAAAAGAACAGAGCCATGA
GGACCAAGGACACATAATGGATACACGGATGAGGAAGAACAAGCAAGCAGGCAGAAAAGTCACTCTAATAGAGTGTGCCAGCTGTCACTT
TTCTCAGGAGTGGTCGATGGAGTTGACTGCTACCTTAACCAGATTTGCCATCGTTCTGAAACTGCCGTGTGTTTTCTAAGGACAACCAGG
TGTTAAGCCTTTCTCTTTAGAAGAAGGACAGTAACCTTTCTGTTAAAGAATTGAAGAAAAGTTAAGAGCTGCCGAAATGCACAGAGGTGA
AAATGACAAACCAAATGGAATTTCTCTTCAGAGTTCAGAATTTTCAGATACTAAGGAGGAAGAAAGGATCCACTACTTCTTGTTCTTATG
AATGACTCTAGAAAAATCAGAATCAAGTTGTGGGTGGAAAAATCAACGTGGCCTTTGAGTTCAGTTGTTATAAACCATTGTGACTATTGT
TGGTCAAAGTATTGGTACTTATATTGTTAGTAATTGCATCATAATTACATTACCAGTGTTGGAAAACTAATGAAGAAAACACTGTAATTG
CTACTCAGCAAATGTGAATAAAAGGTGTTTGCGTTATTAGGATGTCTGTTAAGTAATCATTTAATATTATTATATTGGTAATGGTTGTAT
GTGTGATGCTATGCCCAGAATATGAAGTATCTGTTTTTGAAATTCACTTTATTTAAAAGATAAGCAGCTGACTGGGCACGGTGCCTCATG
CCTGTAATCCTAGCACCTTGGGAGGCTGAGGCAGGTGGATCACCTAAGGTCAGGAGTTCAACAACACCAGCCTGACCAACATGGTGAAAC
CCCATCTCTACTAAAAATACAAAAATCAGCCGGGTCTCATGGCAGGCACCTGTAATCCCATCTACTGAGGCAGGAGAATTGCTTGACCCA

>In-frame_ENST00000395996_ENST00000417892_TCGA-BH-A1F0-01A_VPS13B_chr8_100050794_+_AHI1_chr6_135644462_length(amino acids)=186AA_start in transcript=111_stop in transcript=671
MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSGHIHELRIHVPWTKLGSEPVVITINTMECIL
KLKDGIQVVALYDYTANRSDELTIHRGDIIRVFFKDNEDWWYGSIGKGQEGYFPANHVASETLYQELPPEIKERSPPLSPEEKTKIEKSP

--------------------------------------------------------------
>In-frame_ENST00000358544_ENST00000367800_TCGA-BH-A1F0-01A_VPS13B_chr8_100050794_+_AHI1_chr6_135644462_length(transcript)=2941nt_BP=402nt
GGCGCGGTACAGGAGCAGCACTGCCGGCGGGGGCGGGTGCCAGGGACTTGGAGGTGGAGGGGACGCGGCGGTACTCTGGCGTCTTCCGAC
TTCGACTCCTTACCTTAAAAGATGCTGGAGTCATATGTAACTCCAATTTTAATGAGCTATGTGAATCGCTACATCAAGAACTTAAAGCCG
TCGGATCTACAGCTTTCACTATGGGGTGGAGACGTGGTACTCAGCAAGCTCGAGTTAAAGTTGGATGTGCTGGAACAGGAACTGAAATTA
CCATTCACTTTTTTAAGTGGACATATTCATGAATTGAGGATTCATGTACCATGGACAAAACTGGGTTCAGAACCAGTGGTAATTACCATC
AATACTATGGAATGCATTTTGAAACTTAAGGATGGGATACAGGTAGTGGCTCTTTATGACTACACAGCGAATCGATCAGATGAACTAACC
ATCCATCGCGGAGACATTATCCGAGTGTTTTTCAAAGATAATGAAGACTGGTGGTATGGCAGCATAGGAAAGGGACAGGAAGGTTATTTT
CCAGCTAATCATGTGGCTAGTGAAACACTGTATCAAGAACTGCCTCCTGAGATAAAGGAGCGATCCCCTCCTTTAAGCCCTGAGGAAAAA
ACTAAAATAGAAAAATCTCCAGCTCCTCAAAAGCAATCAATCAATAAGAACAAGTCCCAGGACTTCAGACTAGGCTCAGAATCTATGACA
CATTCTGAAATGAGAAAAGAACAGAGCCATGAGGACCAAGGACACATAATGGATACACGGATGAGGAAGAACAAGCAAGCAGGCAGAAAA
GTCACTCTAATAGAGTAAAGAATTGAAGAAAAGTTAAGAGCTGCCGAAATGCACAGAGGTGAAAATGACAAACCAAATGGAATTTCTCTT
CAGAGTTCAGAATTTTCAGATACTAAGGAGGAAGAAAGGATCCACTACTTCTTGTTCTTATGAATGACTCTAGAAAAATCAGAATCAAGT
TGTGGGTGGAAAAATCAACGTGGCCTTTGAGTTCAGTTGTTATAAACCATTGTGACTATTGTTGGTCAAAGTATTGGTACTTATATTGTT
AGTAATTGCATCATAATTACATTACCAGTGTTGGAAAACTAATGAAGAAAACACTGTAATTGCTACTCAGCAAATGTGAATAAAAGGTGT
TTGCGTTATTAGGATGTCTGTTAAGTAATCATTTAATATTATTATATTGGTAATGGTTGTATGTGTGATGCTATGCCCAGAATATGAAGT
ATCTGTTTTTGAAATTCACTTTATTTAAAAGATAAGCAGCTGACTGGGCACGGTGCCTCATGCCTGTAATCCTAGCACCTTGGGAGGCTG
AGGCAGGTGGATCACCTAAGGTCAGGAGTTCAACAACACCAGCCTGACCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATCA
GCCGGGTCTCATGGCAGGCACCTGTAATCCCATCTACTGAGGCAGGAGAATTGCTTGACCCAGGAGGCAGAGGTTGCAGTGAGCCAAGAT
CACGCCATTGCACTCCAGCCTGGGGGACAGAGCAAGACTCTATCTCCAAAAAACAAAAAAGATAAGCAGCTTTAGAATATGGCGCATTCA
AAACAGTCTCAGTAACAAAGACATTAAAAGAAAACAATTTACTTTCTAATTAAAATTTTGTGTTTCTTAAGATCAAATCATATAGGTAAC
TTCATAGACCTAAATTAAAAGTGATTTTTGGCTGGACTGGCAACAATGTTCCCAATGTCTTTACTTTTTAAAAAAGGCTTTTCATATTTA
AGCACATACCTATTTTGTAGACTTACATTGTTTAATATTTATTTTAATCTTAATATTTTTACATTATTATATTGCATTATTTATTTTTTC
TAAGTTCCAGAATAATAGTGTCATTATTATAGACTATATGTTTTGAAGTTTGATATTATAATGGGATATTCATTTTTTGTTCTTTTCTTG
ACTCCTTTCTCAAGTGTGTGATAAGGTCTGCTGATAAAATATTTAACCCCAAGAAAGTGAAAACTAATATAAAATTAGAAAGACCTATCC
AAATTAGACAGTCAATTCCATTAAAATAAGAAGTGAGAAAAACAATGTTGGGCATTGAGGTGTAAATTTTGCCCAGATGTATACCCAGTG
TGAAATATCTTCTAATAAAAATATATTTGGCTCTTATCCCTGCACATGTAGAGGCATAAAAATTGGTAAACATGTCCCGCTGTGTAGAAC
TTTAAAAAAAAGGCATTTTTGAAAGTGTTGAGTGGCACTGATAACTGGTGAAGCCTACAGCCATCCGCCCAAAAGTCTGTTCTGATGGCA
CTGAGTTTTCATTGTTCTGGATGTATAAGTCTGTGTGTCAGGTACAGCTGGGCCCAGCCAGCTTGAGTCACTCTTGTACAAGCTTGTTTT
TTTCTGTCTTGTGAATGCACTTGATAATTTAAAAATAAAAATATCTGTTTCTCTGCAGTTTCAGCTAATAATTTTGAGATATGTGTTGAT
TTTCTGATTGAATCACCAAGAATTTCAACAAGTTTAGAAATAATTTAAGATGAATGAAAAATATGTCAGGGGGAGCTAAGCATTTGCTAA
GCTCTTGATGTTTATATGAAAAATAAAGGGTTGTTTTTATATTGCAACTACTAAAGAGAAAAATAGCAGTTGAAGCAAACACCAGGAAAA
TTTGGCTCTACTGAAAGCCCAGTCCTTTTCCCCTTTGTCTCGCTGACAAAGTAAGACTAGGGTTATGTTCATGAATAGATTAATAAAAGA
TGTTTCTTTACCACACAATCTGAGATGAGATGGGGTGGGGGAGATCATGACAGTGCCCTCCAAGCAATAGATCCAGCTGATAATCAAGCA

>In-frame_ENST00000358544_ENST00000367800_TCGA-BH-A1F0-01A_VPS13B_chr8_100050794_+_AHI1_chr6_135644462_length(amino acids)=238AA_start in transcript=111_stop in transcript=827
MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSGHIHELRIHVPWTKLGSEPVVITINTMECIL
KLKDGIQVVALYDYTANRSDELTIHRGDIIRVFFKDNEDWWYGSIGKGQEGYFPANHVASETLYQELPPEIKERSPPLSPEEKTKIEKSP

--------------------------------------------------------------
>In-frame_ENST00000358544_ENST00000457866_TCGA-BH-A1F0-01A_VPS13B_chr8_100050794_+_AHI1_chr6_135644462_length(transcript)=2487nt_BP=402nt
GGCGCGGTACAGGAGCAGCACTGCCGGCGGGGGCGGGTGCCAGGGACTTGGAGGTGGAGGGGACGCGGCGGTACTCTGGCGTCTTCCGAC
TTCGACTCCTTACCTTAAAAGATGCTGGAGTCATATGTAACTCCAATTTTAATGAGCTATGTGAATCGCTACATCAAGAACTTAAAGCCG
TCGGATCTACAGCTTTCACTATGGGGTGGAGACGTGGTACTCAGCAAGCTCGAGTTAAAGTTGGATGTGCTGGAACAGGAACTGAAATTA
CCATTCACTTTTTTAAGTGGACATATTCATGAATTGAGGATTCATGTACCATGGACAAAACTGGGTTCAGAACCAGTGGTAATTACCATC
AATACTATGGAATGCATTTTGAAACTTAAGGATGGGATACAGGTAGTGGCTCTTTATGACTACACAGCGAATCGATCAGATGAACTAACC
ATCCATCGCGGAGACATTATCCGAGTGTTTTTCAAAGATAATGAAGACTGGTGGTATGGCAGCATAGGAAAGGGACAGGAAGGTTATTTT
CCAGCTAATCATGTGGCTAGTGAAACACTGTATCAAGAACTGCCTCCTGAGATAAAGGAGCGATCCCCTCCTTTAAGCCCTGAGGAAAAA
ACTAAAATAGAAAAATCTCCAGCTCCTCAAAAGCAATCAATCAATAAGAACAAGTCCCAGGACTTCAGACTAGGCTCAGAATCTATGACA
CATTCTGAAATGAGAAAAGAACAGAGCCATGAGGACCAAGGACACATAATGGATACACGGATGAGGAAGAACAAGCAAGCAGGCAGAAAA
GTCACTCTAATAGAGTAAAGAATTGAAGAAAAGTTAAGAGCTGCCGAAATGCACAGAGGTGAAAATGACAAACCAAATGGAATTTCTCTT
CAGAGTTCAGAATTTTCAGATACTAAGGAGGAAGAAAGGATCCACTACTTCTTGTTCTTATGAATGACTCTAGAAAAATCAGAATCAAGT
TGTGGGTGGAAAAATCAACGTGGCCTTTGAGTTCAGTTGTTATAAACCATTGTGACTATTGTTGGTCAAAGTATTGGTACTTATATTGTT
AGTAATTGCATCATAATTACATTACCAGTGTTGGAAAACTAATGAAGAAAACACTGTAATTGCTACTCAGCAAATGTGAATAAAAGGTGT
TTGCGTTATTAGGATGTCTGTTAAGTAATCATTTAATATTATTATATTGGTAATGGTTGTATGTGTGATGCTATGCCCAGAATATGAAGT
ATCTGTTTTTGAAATTCACTTTATTTAAAAGATAAGCAGCTGACTGGGCACGGTGCCTCATGCCTGTAATCCTAGCACCTTGGGAGGCTG
AGGCAGGTGGATCACCTAAGGTCAGGAGTTCAACAACACCAGCCTGACCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATCA
GCCGGGTCTCATGGCAGGCACCTGTAATCCCATCTACTGAGGCAGGAGAATTGCTTGACCCAGGAGGCAGAGGTTGCAGTGAGCCAAGAT
CACGCCATTGCACTCCAGCCTGGGGGACAGAGCAAGACTCTATCTCCAAAAAACAAAAAAGATAAGCAGCTTTAGAATATGGCGCATTCA
AAACAGTCTCAGTAACAAAGACATTAAAAGAAAACAATTTACTTTCTAATTAAAATTTTGTGTTTCTTAAGATCAAATCATATAGGTAAC
TTCATAGACCTAAATTAAAAGTGATTTTTGGCTGGACTGGCAACAATGTTCCCAATGTCTTTACTTTTTAAAAAAGGCTTTTCATATTTA
AGCACATACCTATTTTGTAGACTTACATTGTTTAATATTTATTTTAATCTTAATATTTTTACATTATTATATTGCATTATTTATTTTTTC
TAAGTTCCAGAATAATAGTGTCATTATTATAGACTATATGTTTTGAAGTTTGATATTATAATGGGATATTCATTTTTTGTTCTTTTCTTG
ACTCCTTTCTCAAGTGTGTGATAAGGTCTGCTGATAAAATATTTAACCCCAAGAAAGTGAAAACTAATATAAAATTAGAAAGACCTATCC
AAATTAGACAGTCAATTCCATTAAAATAAGAAGTGAGAAAAACAATGTTGGGCATTGAGGTGTAAATTTTGCCCAGATGTATACCCAGTG
TGAAATATCTTCTAATAAAAATATATTTGGCTCTTATCCCTGCACATGTAGAGGCATAAAAATTGGTAAACATGTCCCGCTGTGTAGAAC
TTTAAAAAAAAGGCATTTTTGAAAGTGTTGAGTGGCACTGATAACTGGTGAAGCCTACAGCCATCCGCCCAAAAGTCTGTTCTGATGGCA
CTGAGTTTTCATTGTTCTGGATGTATAAGTCTGTGTGTCAGGTACAGCTGGGCCCAGCCAGCTTGAGTCACTCTTGTACAAGCTTGTTTT

>In-frame_ENST00000358544_ENST00000457866_TCGA-BH-A1F0-01A_VPS13B_chr8_100050794_+_AHI1_chr6_135644462_length(amino acids)=238AA_start in transcript=111_stop in transcript=827
MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSGHIHELRIHVPWTKLGSEPVVITINTMECIL
KLKDGIQVVALYDYTANRSDELTIHRGDIIRVFFKDNEDWWYGSIGKGQEGYFPANHVASETLYQELPPEIKERSPPLSPEEKTKIEKSP

--------------------------------------------------------------
>In-frame_ENST00000358544_ENST00000417892_TCGA-BH-A1F0-01A_VPS13B_chr8_100050794_+_AHI1_chr6_135644462_length(transcript)=1965nt_BP=402nt
GGCGCGGTACAGGAGCAGCACTGCCGGCGGGGGCGGGTGCCAGGGACTTGGAGGTGGAGGGGACGCGGCGGTACTCTGGCGTCTTCCGAC
TTCGACTCCTTACCTTAAAAGATGCTGGAGTCATATGTAACTCCAATTTTAATGAGCTATGTGAATCGCTACATCAAGAACTTAAAGCCG
TCGGATCTACAGCTTTCACTATGGGGTGGAGACGTGGTACTCAGCAAGCTCGAGTTAAAGTTGGATGTGCTGGAACAGGAACTGAAATTA
CCATTCACTTTTTTAAGTGGACATATTCATGAATTGAGGATTCATGTACCATGGACAAAACTGGGTTCAGAACCAGTGGTAATTACCATC
AATACTATGGAATGCATTTTGAAACTTAAGGATGGGATACAGGTAGTGGCTCTTTATGACTACACAGCGAATCGATCAGATGAACTAACC
ATCCATCGCGGAGACATTATCCGAGTGTTTTTCAAAGATAATGAAGACTGGTGGTATGGCAGCATAGGAAAGGGACAGGAAGGTTATTTT
CCAGCTAATCATGTGGCTAGTGAAACACTGTATCAAGAACTGCCTCCTGAGATAAAGGAGCGATCCCCTCCTTTAAGCCCTGAGGAAAAA
ACTAAAATAGAAAAATCTCCAGCTCCTCAAAAGGTAAAATAAAACAAAACAGCTCACAGAGACACCTCCTTCTTCCCCCTGCTTCTGCCT
CCATGAGTAACTACCTATATGACGTGCTGCTGCTGAGACCAAGGAATGAATAGTGCCAAATCTTGCTGAAGAATGATCTTGCAGAAATCT
GATTGTGAAGAAGGAAATCTAAAAAGGCCAAACAAGCTTCAGTAGAGATAACACCAGGAAAGCAGTTACTCAAACAAGACTGAAAGAGAA
GCAATCAATCAATAAGAACAAGTCCCAGGACTTCAGACTAGGCTCAGAATCTATGACACATTCTGAAATGAGAAAAGAACAGAGCCATGA
GGACCAAGGACACATAATGGATACACGGATGAGGAAGAACAAGCAAGCAGGCAGAAAAGTCACTCTAATAGAGTGTGCCAGCTGTCACTT
TTCTCAGGAGTGGTCGATGGAGTTGACTGCTACCTTAACCAGATTTGCCATCGTTCTGAAACTGCCGTGTGTTTTCTAAGGACAACCAGG
TGTTAAGCCTTTCTCTTTAGAAGAAGGACAGTAACCTTTCTGTTAAAGAATTGAAGAAAAGTTAAGAGCTGCCGAAATGCACAGAGGTGA
AAATGACAAACCAAATGGAATTTCTCTTCAGAGTTCAGAATTTTCAGATACTAAGGAGGAAGAAAGGATCCACTACTTCTTGTTCTTATG
AATGACTCTAGAAAAATCAGAATCAAGTTGTGGGTGGAAAAATCAACGTGGCCTTTGAGTTCAGTTGTTATAAACCATTGTGACTATTGT
TGGTCAAAGTATTGGTACTTATATTGTTAGTAATTGCATCATAATTACATTACCAGTGTTGGAAAACTAATGAAGAAAACACTGTAATTG
CTACTCAGCAAATGTGAATAAAAGGTGTTTGCGTTATTAGGATGTCTGTTAAGTAATCATTTAATATTATTATATTGGTAATGGTTGTAT
GTGTGATGCTATGCCCAGAATATGAAGTATCTGTTTTTGAAATTCACTTTATTTAAAAGATAAGCAGCTGACTGGGCACGGTGCCTCATG
CCTGTAATCCTAGCACCTTGGGAGGCTGAGGCAGGTGGATCACCTAAGGTCAGGAGTTCAACAACACCAGCCTGACCAACATGGTGAAAC
CCCATCTCTACTAAAAATACAAAAATCAGCCGGGTCTCATGGCAGGCACCTGTAATCCCATCTACTGAGGCAGGAGAATTGCTTGACCCA

>In-frame_ENST00000358544_ENST00000417892_TCGA-BH-A1F0-01A_VPS13B_chr8_100050794_+_AHI1_chr6_135644462_length(amino acids)=186AA_start in transcript=111_stop in transcript=671
MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSGHIHELRIHVPWTKLGSEPVVITINTMECIL
KLKDGIQVVALYDYTANRSDELTIHRGDIIRVFFKDNEDWWYGSIGKGQEGYFPANHVASETLYQELPPEIKERSPPLSPEEKTKIEKSP

--------------------------------------------------------------
>In-frame_ENST00000357162_ENST00000367800_TCGA-BH-A1F0-01A_VPS13B_chr8_100050794_+_AHI1_chr6_135644462_length(transcript)=2941nt_BP=402nt
GGCGCGGTACAGGAGCAGCACTGCCGGCGGGGGCGGGTGCCAGGGACTTGGAGGTGGAGGGGACGCGGCGGTACTCTGGCGTCTTCCGAC
TTCGACTCCTTACCTTAAAAGATGCTGGAGTCATATGTAACTCCAATTTTAATGAGCTATGTGAATCGCTACATCAAGAACTTAAAGCCG
TCGGATCTACAGCTTTCACTATGGGGTGGAGACGTGGTACTCAGCAAGCTCGAGTTAAAGTTGGATGTGCTGGAACAGGAACTGAAATTA
CCATTCACTTTTTTAAGTGGACATATTCATGAATTGAGGATTCATGTACCATGGACAAAACTGGGTTCAGAACCAGTGGTAATTACCATC
AATACTATGGAATGCATTTTGAAACTTAAGGATGGGATACAGGTAGTGGCTCTTTATGACTACACAGCGAATCGATCAGATGAACTAACC
ATCCATCGCGGAGACATTATCCGAGTGTTTTTCAAAGATAATGAAGACTGGTGGTATGGCAGCATAGGAAAGGGACAGGAAGGTTATTTT
CCAGCTAATCATGTGGCTAGTGAAACACTGTATCAAGAACTGCCTCCTGAGATAAAGGAGCGATCCCCTCCTTTAAGCCCTGAGGAAAAA
ACTAAAATAGAAAAATCTCCAGCTCCTCAAAAGCAATCAATCAATAAGAACAAGTCCCAGGACTTCAGACTAGGCTCAGAATCTATGACA
CATTCTGAAATGAGAAAAGAACAGAGCCATGAGGACCAAGGACACATAATGGATACACGGATGAGGAAGAACAAGCAAGCAGGCAGAAAA
GTCACTCTAATAGAGTAAAGAATTGAAGAAAAGTTAAGAGCTGCCGAAATGCACAGAGGTGAAAATGACAAACCAAATGGAATTTCTCTT
CAGAGTTCAGAATTTTCAGATACTAAGGAGGAAGAAAGGATCCACTACTTCTTGTTCTTATGAATGACTCTAGAAAAATCAGAATCAAGT
TGTGGGTGGAAAAATCAACGTGGCCTTTGAGTTCAGTTGTTATAAACCATTGTGACTATTGTTGGTCAAAGTATTGGTACTTATATTGTT
AGTAATTGCATCATAATTACATTACCAGTGTTGGAAAACTAATGAAGAAAACACTGTAATTGCTACTCAGCAAATGTGAATAAAAGGTGT
TTGCGTTATTAGGATGTCTGTTAAGTAATCATTTAATATTATTATATTGGTAATGGTTGTATGTGTGATGCTATGCCCAGAATATGAAGT
ATCTGTTTTTGAAATTCACTTTATTTAAAAGATAAGCAGCTGACTGGGCACGGTGCCTCATGCCTGTAATCCTAGCACCTTGGGAGGCTG
AGGCAGGTGGATCACCTAAGGTCAGGAGTTCAACAACACCAGCCTGACCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATCA
GCCGGGTCTCATGGCAGGCACCTGTAATCCCATCTACTGAGGCAGGAGAATTGCTTGACCCAGGAGGCAGAGGTTGCAGTGAGCCAAGAT
CACGCCATTGCACTCCAGCCTGGGGGACAGAGCAAGACTCTATCTCCAAAAAACAAAAAAGATAAGCAGCTTTAGAATATGGCGCATTCA
AAACAGTCTCAGTAACAAAGACATTAAAAGAAAACAATTTACTTTCTAATTAAAATTTTGTGTTTCTTAAGATCAAATCATATAGGTAAC
TTCATAGACCTAAATTAAAAGTGATTTTTGGCTGGACTGGCAACAATGTTCCCAATGTCTTTACTTTTTAAAAAAGGCTTTTCATATTTA
AGCACATACCTATTTTGTAGACTTACATTGTTTAATATTTATTTTAATCTTAATATTTTTACATTATTATATTGCATTATTTATTTTTTC
TAAGTTCCAGAATAATAGTGTCATTATTATAGACTATATGTTTTGAAGTTTGATATTATAATGGGATATTCATTTTTTGTTCTTTTCTTG
ACTCCTTTCTCAAGTGTGTGATAAGGTCTGCTGATAAAATATTTAACCCCAAGAAAGTGAAAACTAATATAAAATTAGAAAGACCTATCC
AAATTAGACAGTCAATTCCATTAAAATAAGAAGTGAGAAAAACAATGTTGGGCATTGAGGTGTAAATTTTGCCCAGATGTATACCCAGTG
TGAAATATCTTCTAATAAAAATATATTTGGCTCTTATCCCTGCACATGTAGAGGCATAAAAATTGGTAAACATGTCCCGCTGTGTAGAAC
TTTAAAAAAAAGGCATTTTTGAAAGTGTTGAGTGGCACTGATAACTGGTGAAGCCTACAGCCATCCGCCCAAAAGTCTGTTCTGATGGCA
CTGAGTTTTCATTGTTCTGGATGTATAAGTCTGTGTGTCAGGTACAGCTGGGCCCAGCCAGCTTGAGTCACTCTTGTACAAGCTTGTTTT
TTTCTGTCTTGTGAATGCACTTGATAATTTAAAAATAAAAATATCTGTTTCTCTGCAGTTTCAGCTAATAATTTTGAGATATGTGTTGAT
TTTCTGATTGAATCACCAAGAATTTCAACAAGTTTAGAAATAATTTAAGATGAATGAAAAATATGTCAGGGGGAGCTAAGCATTTGCTAA
GCTCTTGATGTTTATATGAAAAATAAAGGGTTGTTTTTATATTGCAACTACTAAAGAGAAAAATAGCAGTTGAAGCAAACACCAGGAAAA
TTTGGCTCTACTGAAAGCCCAGTCCTTTTCCCCTTTGTCTCGCTGACAAAGTAAGACTAGGGTTATGTTCATGAATAGATTAATAAAAGA
TGTTTCTTTACCACACAATCTGAGATGAGATGGGGTGGGGGAGATCATGACAGTGCCCTCCAAGCAATAGATCCAGCTGATAATCAAGCA

>In-frame_ENST00000357162_ENST00000367800_TCGA-BH-A1F0-01A_VPS13B_chr8_100050794_+_AHI1_chr6_135644462_length(amino acids)=238AA_start in transcript=111_stop in transcript=827
MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSGHIHELRIHVPWTKLGSEPVVITINTMECIL
KLKDGIQVVALYDYTANRSDELTIHRGDIIRVFFKDNEDWWYGSIGKGQEGYFPANHVASETLYQELPPEIKERSPPLSPEEKTKIEKSP

--------------------------------------------------------------
>In-frame_ENST00000357162_ENST00000457866_TCGA-BH-A1F0-01A_VPS13B_chr8_100050794_+_AHI1_chr6_135644462_length(transcript)=2487nt_BP=402nt
GGCGCGGTACAGGAGCAGCACTGCCGGCGGGGGCGGGTGCCAGGGACTTGGAGGTGGAGGGGACGCGGCGGTACTCTGGCGTCTTCCGAC
TTCGACTCCTTACCTTAAAAGATGCTGGAGTCATATGTAACTCCAATTTTAATGAGCTATGTGAATCGCTACATCAAGAACTTAAAGCCG
TCGGATCTACAGCTTTCACTATGGGGTGGAGACGTGGTACTCAGCAAGCTCGAGTTAAAGTTGGATGTGCTGGAACAGGAACTGAAATTA
CCATTCACTTTTTTAAGTGGACATATTCATGAATTGAGGATTCATGTACCATGGACAAAACTGGGTTCAGAACCAGTGGTAATTACCATC
AATACTATGGAATGCATTTTGAAACTTAAGGATGGGATACAGGTAGTGGCTCTTTATGACTACACAGCGAATCGATCAGATGAACTAACC
ATCCATCGCGGAGACATTATCCGAGTGTTTTTCAAAGATAATGAAGACTGGTGGTATGGCAGCATAGGAAAGGGACAGGAAGGTTATTTT
CCAGCTAATCATGTGGCTAGTGAAACACTGTATCAAGAACTGCCTCCTGAGATAAAGGAGCGATCCCCTCCTTTAAGCCCTGAGGAAAAA
ACTAAAATAGAAAAATCTCCAGCTCCTCAAAAGCAATCAATCAATAAGAACAAGTCCCAGGACTTCAGACTAGGCTCAGAATCTATGACA
CATTCTGAAATGAGAAAAGAACAGAGCCATGAGGACCAAGGACACATAATGGATACACGGATGAGGAAGAACAAGCAAGCAGGCAGAAAA
GTCACTCTAATAGAGTAAAGAATTGAAGAAAAGTTAAGAGCTGCCGAAATGCACAGAGGTGAAAATGACAAACCAAATGGAATTTCTCTT
CAGAGTTCAGAATTTTCAGATACTAAGGAGGAAGAAAGGATCCACTACTTCTTGTTCTTATGAATGACTCTAGAAAAATCAGAATCAAGT
TGTGGGTGGAAAAATCAACGTGGCCTTTGAGTTCAGTTGTTATAAACCATTGTGACTATTGTTGGTCAAAGTATTGGTACTTATATTGTT
AGTAATTGCATCATAATTACATTACCAGTGTTGGAAAACTAATGAAGAAAACACTGTAATTGCTACTCAGCAAATGTGAATAAAAGGTGT
TTGCGTTATTAGGATGTCTGTTAAGTAATCATTTAATATTATTATATTGGTAATGGTTGTATGTGTGATGCTATGCCCAGAATATGAAGT
ATCTGTTTTTGAAATTCACTTTATTTAAAAGATAAGCAGCTGACTGGGCACGGTGCCTCATGCCTGTAATCCTAGCACCTTGGGAGGCTG
AGGCAGGTGGATCACCTAAGGTCAGGAGTTCAACAACACCAGCCTGACCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATCA
GCCGGGTCTCATGGCAGGCACCTGTAATCCCATCTACTGAGGCAGGAGAATTGCTTGACCCAGGAGGCAGAGGTTGCAGTGAGCCAAGAT
CACGCCATTGCACTCCAGCCTGGGGGACAGAGCAAGACTCTATCTCCAAAAAACAAAAAAGATAAGCAGCTTTAGAATATGGCGCATTCA
AAACAGTCTCAGTAACAAAGACATTAAAAGAAAACAATTTACTTTCTAATTAAAATTTTGTGTTTCTTAAGATCAAATCATATAGGTAAC
TTCATAGACCTAAATTAAAAGTGATTTTTGGCTGGACTGGCAACAATGTTCCCAATGTCTTTACTTTTTAAAAAAGGCTTTTCATATTTA
AGCACATACCTATTTTGTAGACTTACATTGTTTAATATTTATTTTAATCTTAATATTTTTACATTATTATATTGCATTATTTATTTTTTC
TAAGTTCCAGAATAATAGTGTCATTATTATAGACTATATGTTTTGAAGTTTGATATTATAATGGGATATTCATTTTTTGTTCTTTTCTTG
ACTCCTTTCTCAAGTGTGTGATAAGGTCTGCTGATAAAATATTTAACCCCAAGAAAGTGAAAACTAATATAAAATTAGAAAGACCTATCC
AAATTAGACAGTCAATTCCATTAAAATAAGAAGTGAGAAAAACAATGTTGGGCATTGAGGTGTAAATTTTGCCCAGATGTATACCCAGTG
TGAAATATCTTCTAATAAAAATATATTTGGCTCTTATCCCTGCACATGTAGAGGCATAAAAATTGGTAAACATGTCCCGCTGTGTAGAAC
TTTAAAAAAAAGGCATTTTTGAAAGTGTTGAGTGGCACTGATAACTGGTGAAGCCTACAGCCATCCGCCCAAAAGTCTGTTCTGATGGCA
CTGAGTTTTCATTGTTCTGGATGTATAAGTCTGTGTGTCAGGTACAGCTGGGCCCAGCCAGCTTGAGTCACTCTTGTACAAGCTTGTTTT

>In-frame_ENST00000357162_ENST00000457866_TCGA-BH-A1F0-01A_VPS13B_chr8_100050794_+_AHI1_chr6_135644462_length(amino acids)=238AA_start in transcript=111_stop in transcript=827
MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSGHIHELRIHVPWTKLGSEPVVITINTMECIL
KLKDGIQVVALYDYTANRSDELTIHRGDIIRVFFKDNEDWWYGSIGKGQEGYFPANHVASETLYQELPPEIKERSPPLSPEEKTKIEKSP

--------------------------------------------------------------
>In-frame_ENST00000357162_ENST00000417892_TCGA-BH-A1F0-01A_VPS13B_chr8_100050794_+_AHI1_chr6_135644462_length(transcript)=1965nt_BP=402nt
GGCGCGGTACAGGAGCAGCACTGCCGGCGGGGGCGGGTGCCAGGGACTTGGAGGTGGAGGGGACGCGGCGGTACTCTGGCGTCTTCCGAC
TTCGACTCCTTACCTTAAAAGATGCTGGAGTCATATGTAACTCCAATTTTAATGAGCTATGTGAATCGCTACATCAAGAACTTAAAGCCG
TCGGATCTACAGCTTTCACTATGGGGTGGAGACGTGGTACTCAGCAAGCTCGAGTTAAAGTTGGATGTGCTGGAACAGGAACTGAAATTA
CCATTCACTTTTTTAAGTGGACATATTCATGAATTGAGGATTCATGTACCATGGACAAAACTGGGTTCAGAACCAGTGGTAATTACCATC
AATACTATGGAATGCATTTTGAAACTTAAGGATGGGATACAGGTAGTGGCTCTTTATGACTACACAGCGAATCGATCAGATGAACTAACC
ATCCATCGCGGAGACATTATCCGAGTGTTTTTCAAAGATAATGAAGACTGGTGGTATGGCAGCATAGGAAAGGGACAGGAAGGTTATTTT
CCAGCTAATCATGTGGCTAGTGAAACACTGTATCAAGAACTGCCTCCTGAGATAAAGGAGCGATCCCCTCCTTTAAGCCCTGAGGAAAAA
ACTAAAATAGAAAAATCTCCAGCTCCTCAAAAGGTAAAATAAAACAAAACAGCTCACAGAGACACCTCCTTCTTCCCCCTGCTTCTGCCT
CCATGAGTAACTACCTATATGACGTGCTGCTGCTGAGACCAAGGAATGAATAGTGCCAAATCTTGCTGAAGAATGATCTTGCAGAAATCT
GATTGTGAAGAAGGAAATCTAAAAAGGCCAAACAAGCTTCAGTAGAGATAACACCAGGAAAGCAGTTACTCAAACAAGACTGAAAGAGAA
GCAATCAATCAATAAGAACAAGTCCCAGGACTTCAGACTAGGCTCAGAATCTATGACACATTCTGAAATGAGAAAAGAACAGAGCCATGA
GGACCAAGGACACATAATGGATACACGGATGAGGAAGAACAAGCAAGCAGGCAGAAAAGTCACTCTAATAGAGTGTGCCAGCTGTCACTT
TTCTCAGGAGTGGTCGATGGAGTTGACTGCTACCTTAACCAGATTTGCCATCGTTCTGAAACTGCCGTGTGTTTTCTAAGGACAACCAGG
TGTTAAGCCTTTCTCTTTAGAAGAAGGACAGTAACCTTTCTGTTAAAGAATTGAAGAAAAGTTAAGAGCTGCCGAAATGCACAGAGGTGA
AAATGACAAACCAAATGGAATTTCTCTTCAGAGTTCAGAATTTTCAGATACTAAGGAGGAAGAAAGGATCCACTACTTCTTGTTCTTATG
AATGACTCTAGAAAAATCAGAATCAAGTTGTGGGTGGAAAAATCAACGTGGCCTTTGAGTTCAGTTGTTATAAACCATTGTGACTATTGT
TGGTCAAAGTATTGGTACTTATATTGTTAGTAATTGCATCATAATTACATTACCAGTGTTGGAAAACTAATGAAGAAAACACTGTAATTG
CTACTCAGCAAATGTGAATAAAAGGTGTTTGCGTTATTAGGATGTCTGTTAAGTAATCATTTAATATTATTATATTGGTAATGGTTGTAT
GTGTGATGCTATGCCCAGAATATGAAGTATCTGTTTTTGAAATTCACTTTATTTAAAAGATAAGCAGCTGACTGGGCACGGTGCCTCATG
CCTGTAATCCTAGCACCTTGGGAGGCTGAGGCAGGTGGATCACCTAAGGTCAGGAGTTCAACAACACCAGCCTGACCAACATGGTGAAAC
CCCATCTCTACTAAAAATACAAAAATCAGCCGGGTCTCATGGCAGGCACCTGTAATCCCATCTACTGAGGCAGGAGAATTGCTTGACCCA

>In-frame_ENST00000357162_ENST00000417892_TCGA-BH-A1F0-01A_VPS13B_chr8_100050794_+_AHI1_chr6_135644462_length(amino acids)=186AA_start in transcript=111_stop in transcript=671
MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSGHIHELRIHVPWTKLGSEPVVITINTMECIL
KLKDGIQVVALYDYTANRSDELTIHRGDIIRVFFKDNEDWWYGSIGKGQEGYFPANHVASETLYQELPPEIKERSPPLSPEEKTKIEKSP

--------------------------------------------------------------
>In-frame_ENST00000355155_ENST00000367800_TCGA-BH-A1F0-01A_VPS13B_chr8_100050794_+_AHI1_chr6_135644462_length(transcript)=2941nt_BP=402nt
GGCGCGGTACAGGAGCAGCACTGCCGGCGGGGGCGGGTGCCAGGGACTTGGAGGTGGAGGGGACGCGGCGGTACTCTGGCGTCTTCCGAC
TTCGACTCCTTACCTTAAAAGATGCTGGAGTCATATGTAACTCCAATTTTAATGAGCTATGTGAATCGCTACATCAAGAACTTAAAGCCG
TCGGATCTACAGCTTTCACTATGGGGTGGAGACGTGGTACTCAGCAAGCTCGAGTTAAAGTTGGATGTGCTGGAACAGGAACTGAAATTA
CCATTCACTTTTTTAAGTGGACATATTCATGAATTGAGGATTCATGTACCATGGACAAAACTGGGTTCAGAACCAGTGGTAATTACCATC
AATACTATGGAATGCATTTTGAAACTTAAGGATGGGATACAGGTAGTGGCTCTTTATGACTACACAGCGAATCGATCAGATGAACTAACC
ATCCATCGCGGAGACATTATCCGAGTGTTTTTCAAAGATAATGAAGACTGGTGGTATGGCAGCATAGGAAAGGGACAGGAAGGTTATTTT
CCAGCTAATCATGTGGCTAGTGAAACACTGTATCAAGAACTGCCTCCTGAGATAAAGGAGCGATCCCCTCCTTTAAGCCCTGAGGAAAAA
ACTAAAATAGAAAAATCTCCAGCTCCTCAAAAGCAATCAATCAATAAGAACAAGTCCCAGGACTTCAGACTAGGCTCAGAATCTATGACA
CATTCTGAAATGAGAAAAGAACAGAGCCATGAGGACCAAGGACACATAATGGATACACGGATGAGGAAGAACAAGCAAGCAGGCAGAAAA
GTCACTCTAATAGAGTAAAGAATTGAAGAAAAGTTAAGAGCTGCCGAAATGCACAGAGGTGAAAATGACAAACCAAATGGAATTTCTCTT
CAGAGTTCAGAATTTTCAGATACTAAGGAGGAAGAAAGGATCCACTACTTCTTGTTCTTATGAATGACTCTAGAAAAATCAGAATCAAGT
TGTGGGTGGAAAAATCAACGTGGCCTTTGAGTTCAGTTGTTATAAACCATTGTGACTATTGTTGGTCAAAGTATTGGTACTTATATTGTT
AGTAATTGCATCATAATTACATTACCAGTGTTGGAAAACTAATGAAGAAAACACTGTAATTGCTACTCAGCAAATGTGAATAAAAGGTGT
TTGCGTTATTAGGATGTCTGTTAAGTAATCATTTAATATTATTATATTGGTAATGGTTGTATGTGTGATGCTATGCCCAGAATATGAAGT
ATCTGTTTTTGAAATTCACTTTATTTAAAAGATAAGCAGCTGACTGGGCACGGTGCCTCATGCCTGTAATCCTAGCACCTTGGGAGGCTG
AGGCAGGTGGATCACCTAAGGTCAGGAGTTCAACAACACCAGCCTGACCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATCA
GCCGGGTCTCATGGCAGGCACCTGTAATCCCATCTACTGAGGCAGGAGAATTGCTTGACCCAGGAGGCAGAGGTTGCAGTGAGCCAAGAT
CACGCCATTGCACTCCAGCCTGGGGGACAGAGCAAGACTCTATCTCCAAAAAACAAAAAAGATAAGCAGCTTTAGAATATGGCGCATTCA
AAACAGTCTCAGTAACAAAGACATTAAAAGAAAACAATTTACTTTCTAATTAAAATTTTGTGTTTCTTAAGATCAAATCATATAGGTAAC
TTCATAGACCTAAATTAAAAGTGATTTTTGGCTGGACTGGCAACAATGTTCCCAATGTCTTTACTTTTTAAAAAAGGCTTTTCATATTTA
AGCACATACCTATTTTGTAGACTTACATTGTTTAATATTTATTTTAATCTTAATATTTTTACATTATTATATTGCATTATTTATTTTTTC
TAAGTTCCAGAATAATAGTGTCATTATTATAGACTATATGTTTTGAAGTTTGATATTATAATGGGATATTCATTTTTTGTTCTTTTCTTG
ACTCCTTTCTCAAGTGTGTGATAAGGTCTGCTGATAAAATATTTAACCCCAAGAAAGTGAAAACTAATATAAAATTAGAAAGACCTATCC
AAATTAGACAGTCAATTCCATTAAAATAAGAAGTGAGAAAAACAATGTTGGGCATTGAGGTGTAAATTTTGCCCAGATGTATACCCAGTG
TGAAATATCTTCTAATAAAAATATATTTGGCTCTTATCCCTGCACATGTAGAGGCATAAAAATTGGTAAACATGTCCCGCTGTGTAGAAC
TTTAAAAAAAAGGCATTTTTGAAAGTGTTGAGTGGCACTGATAACTGGTGAAGCCTACAGCCATCCGCCCAAAAGTCTGTTCTGATGGCA
CTGAGTTTTCATTGTTCTGGATGTATAAGTCTGTGTGTCAGGTACAGCTGGGCCCAGCCAGCTTGAGTCACTCTTGTACAAGCTTGTTTT
TTTCTGTCTTGTGAATGCACTTGATAATTTAAAAATAAAAATATCTGTTTCTCTGCAGTTTCAGCTAATAATTTTGAGATATGTGTTGAT
TTTCTGATTGAATCACCAAGAATTTCAACAAGTTTAGAAATAATTTAAGATGAATGAAAAATATGTCAGGGGGAGCTAAGCATTTGCTAA
GCTCTTGATGTTTATATGAAAAATAAAGGGTTGTTTTTATATTGCAACTACTAAAGAGAAAAATAGCAGTTGAAGCAAACACCAGGAAAA
TTTGGCTCTACTGAAAGCCCAGTCCTTTTCCCCTTTGTCTCGCTGACAAAGTAAGACTAGGGTTATGTTCATGAATAGATTAATAAAAGA
TGTTTCTTTACCACACAATCTGAGATGAGATGGGGTGGGGGAGATCATGACAGTGCCCTCCAAGCAATAGATCCAGCTGATAATCAAGCA

>In-frame_ENST00000355155_ENST00000367800_TCGA-BH-A1F0-01A_VPS13B_chr8_100050794_+_AHI1_chr6_135644462_length(amino acids)=238AA_start in transcript=111_stop in transcript=827
MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSGHIHELRIHVPWTKLGSEPVVITINTMECIL
KLKDGIQVVALYDYTANRSDELTIHRGDIIRVFFKDNEDWWYGSIGKGQEGYFPANHVASETLYQELPPEIKERSPPLSPEEKTKIEKSP

--------------------------------------------------------------
>In-frame_ENST00000355155_ENST00000457866_TCGA-BH-A1F0-01A_VPS13B_chr8_100050794_+_AHI1_chr6_135644462_length(transcript)=2487nt_BP=402nt
GGCGCGGTACAGGAGCAGCACTGCCGGCGGGGGCGGGTGCCAGGGACTTGGAGGTGGAGGGGACGCGGCGGTACTCTGGCGTCTTCCGAC
TTCGACTCCTTACCTTAAAAGATGCTGGAGTCATATGTAACTCCAATTTTAATGAGCTATGTGAATCGCTACATCAAGAACTTAAAGCCG
TCGGATCTACAGCTTTCACTATGGGGTGGAGACGTGGTACTCAGCAAGCTCGAGTTAAAGTTGGATGTGCTGGAACAGGAACTGAAATTA
CCATTCACTTTTTTAAGTGGACATATTCATGAATTGAGGATTCATGTACCATGGACAAAACTGGGTTCAGAACCAGTGGTAATTACCATC
AATACTATGGAATGCATTTTGAAACTTAAGGATGGGATACAGGTAGTGGCTCTTTATGACTACACAGCGAATCGATCAGATGAACTAACC
ATCCATCGCGGAGACATTATCCGAGTGTTTTTCAAAGATAATGAAGACTGGTGGTATGGCAGCATAGGAAAGGGACAGGAAGGTTATTTT
CCAGCTAATCATGTGGCTAGTGAAACACTGTATCAAGAACTGCCTCCTGAGATAAAGGAGCGATCCCCTCCTTTAAGCCCTGAGGAAAAA
ACTAAAATAGAAAAATCTCCAGCTCCTCAAAAGCAATCAATCAATAAGAACAAGTCCCAGGACTTCAGACTAGGCTCAGAATCTATGACA
CATTCTGAAATGAGAAAAGAACAGAGCCATGAGGACCAAGGACACATAATGGATACACGGATGAGGAAGAACAAGCAAGCAGGCAGAAAA
GTCACTCTAATAGAGTAAAGAATTGAAGAAAAGTTAAGAGCTGCCGAAATGCACAGAGGTGAAAATGACAAACCAAATGGAATTTCTCTT
CAGAGTTCAGAATTTTCAGATACTAAGGAGGAAGAAAGGATCCACTACTTCTTGTTCTTATGAATGACTCTAGAAAAATCAGAATCAAGT
TGTGGGTGGAAAAATCAACGTGGCCTTTGAGTTCAGTTGTTATAAACCATTGTGACTATTGTTGGTCAAAGTATTGGTACTTATATTGTT
AGTAATTGCATCATAATTACATTACCAGTGTTGGAAAACTAATGAAGAAAACACTGTAATTGCTACTCAGCAAATGTGAATAAAAGGTGT
TTGCGTTATTAGGATGTCTGTTAAGTAATCATTTAATATTATTATATTGGTAATGGTTGTATGTGTGATGCTATGCCCAGAATATGAAGT
ATCTGTTTTTGAAATTCACTTTATTTAAAAGATAAGCAGCTGACTGGGCACGGTGCCTCATGCCTGTAATCCTAGCACCTTGGGAGGCTG
AGGCAGGTGGATCACCTAAGGTCAGGAGTTCAACAACACCAGCCTGACCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATCA
GCCGGGTCTCATGGCAGGCACCTGTAATCCCATCTACTGAGGCAGGAGAATTGCTTGACCCAGGAGGCAGAGGTTGCAGTGAGCCAAGAT
CACGCCATTGCACTCCAGCCTGGGGGACAGAGCAAGACTCTATCTCCAAAAAACAAAAAAGATAAGCAGCTTTAGAATATGGCGCATTCA
AAACAGTCTCAGTAACAAAGACATTAAAAGAAAACAATTTACTTTCTAATTAAAATTTTGTGTTTCTTAAGATCAAATCATATAGGTAAC
TTCATAGACCTAAATTAAAAGTGATTTTTGGCTGGACTGGCAACAATGTTCCCAATGTCTTTACTTTTTAAAAAAGGCTTTTCATATTTA
AGCACATACCTATTTTGTAGACTTACATTGTTTAATATTTATTTTAATCTTAATATTTTTACATTATTATATTGCATTATTTATTTTTTC
TAAGTTCCAGAATAATAGTGTCATTATTATAGACTATATGTTTTGAAGTTTGATATTATAATGGGATATTCATTTTTTGTTCTTTTCTTG
ACTCCTTTCTCAAGTGTGTGATAAGGTCTGCTGATAAAATATTTAACCCCAAGAAAGTGAAAACTAATATAAAATTAGAAAGACCTATCC
AAATTAGACAGTCAATTCCATTAAAATAAGAAGTGAGAAAAACAATGTTGGGCATTGAGGTGTAAATTTTGCCCAGATGTATACCCAGTG
TGAAATATCTTCTAATAAAAATATATTTGGCTCTTATCCCTGCACATGTAGAGGCATAAAAATTGGTAAACATGTCCCGCTGTGTAGAAC
TTTAAAAAAAAGGCATTTTTGAAAGTGTTGAGTGGCACTGATAACTGGTGAAGCCTACAGCCATCCGCCCAAAAGTCTGTTCTGATGGCA
CTGAGTTTTCATTGTTCTGGATGTATAAGTCTGTGTGTCAGGTACAGCTGGGCCCAGCCAGCTTGAGTCACTCTTGTACAAGCTTGTTTT

>In-frame_ENST00000355155_ENST00000457866_TCGA-BH-A1F0-01A_VPS13B_chr8_100050794_+_AHI1_chr6_135644462_length(amino acids)=238AA_start in transcript=111_stop in transcript=827
MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSGHIHELRIHVPWTKLGSEPVVITINTMECIL
KLKDGIQVVALYDYTANRSDELTIHRGDIIRVFFKDNEDWWYGSIGKGQEGYFPANHVASETLYQELPPEIKERSPPLSPEEKTKIEKSP

--------------------------------------------------------------
>In-frame_ENST00000355155_ENST00000417892_TCGA-BH-A1F0-01A_VPS13B_chr8_100050794_+_AHI1_chr6_135644462_length(transcript)=1965nt_BP=402nt
GGCGCGGTACAGGAGCAGCACTGCCGGCGGGGGCGGGTGCCAGGGACTTGGAGGTGGAGGGGACGCGGCGGTACTCTGGCGTCTTCCGAC
TTCGACTCCTTACCTTAAAAGATGCTGGAGTCATATGTAACTCCAATTTTAATGAGCTATGTGAATCGCTACATCAAGAACTTAAAGCCG
TCGGATCTACAGCTTTCACTATGGGGTGGAGACGTGGTACTCAGCAAGCTCGAGTTAAAGTTGGATGTGCTGGAACAGGAACTGAAATTA
CCATTCACTTTTTTAAGTGGACATATTCATGAATTGAGGATTCATGTACCATGGACAAAACTGGGTTCAGAACCAGTGGTAATTACCATC
AATACTATGGAATGCATTTTGAAACTTAAGGATGGGATACAGGTAGTGGCTCTTTATGACTACACAGCGAATCGATCAGATGAACTAACC
ATCCATCGCGGAGACATTATCCGAGTGTTTTTCAAAGATAATGAAGACTGGTGGTATGGCAGCATAGGAAAGGGACAGGAAGGTTATTTT
CCAGCTAATCATGTGGCTAGTGAAACACTGTATCAAGAACTGCCTCCTGAGATAAAGGAGCGATCCCCTCCTTTAAGCCCTGAGGAAAAA
ACTAAAATAGAAAAATCTCCAGCTCCTCAAAAGGTAAAATAAAACAAAACAGCTCACAGAGACACCTCCTTCTTCCCCCTGCTTCTGCCT
CCATGAGTAACTACCTATATGACGTGCTGCTGCTGAGACCAAGGAATGAATAGTGCCAAATCTTGCTGAAGAATGATCTTGCAGAAATCT
GATTGTGAAGAAGGAAATCTAAAAAGGCCAAACAAGCTTCAGTAGAGATAACACCAGGAAAGCAGTTACTCAAACAAGACTGAAAGAGAA
GCAATCAATCAATAAGAACAAGTCCCAGGACTTCAGACTAGGCTCAGAATCTATGACACATTCTGAAATGAGAAAAGAACAGAGCCATGA
GGACCAAGGACACATAATGGATACACGGATGAGGAAGAACAAGCAAGCAGGCAGAAAAGTCACTCTAATAGAGTGTGCCAGCTGTCACTT
TTCTCAGGAGTGGTCGATGGAGTTGACTGCTACCTTAACCAGATTTGCCATCGTTCTGAAACTGCCGTGTGTTTTCTAAGGACAACCAGG
TGTTAAGCCTTTCTCTTTAGAAGAAGGACAGTAACCTTTCTGTTAAAGAATTGAAGAAAAGTTAAGAGCTGCCGAAATGCACAGAGGTGA
AAATGACAAACCAAATGGAATTTCTCTTCAGAGTTCAGAATTTTCAGATACTAAGGAGGAAGAAAGGATCCACTACTTCTTGTTCTTATG
AATGACTCTAGAAAAATCAGAATCAAGTTGTGGGTGGAAAAATCAACGTGGCCTTTGAGTTCAGTTGTTATAAACCATTGTGACTATTGT
TGGTCAAAGTATTGGTACTTATATTGTTAGTAATTGCATCATAATTACATTACCAGTGTTGGAAAACTAATGAAGAAAACACTGTAATTG
CTACTCAGCAAATGTGAATAAAAGGTGTTTGCGTTATTAGGATGTCTGTTAAGTAATCATTTAATATTATTATATTGGTAATGGTTGTAT
GTGTGATGCTATGCCCAGAATATGAAGTATCTGTTTTTGAAATTCACTTTATTTAAAAGATAAGCAGCTGACTGGGCACGGTGCCTCATG
CCTGTAATCCTAGCACCTTGGGAGGCTGAGGCAGGTGGATCACCTAAGGTCAGGAGTTCAACAACACCAGCCTGACCAACATGGTGAAAC
CCCATCTCTACTAAAAATACAAAAATCAGCCGGGTCTCATGGCAGGCACCTGTAATCCCATCTACTGAGGCAGGAGAATTGCTTGACCCA

>In-frame_ENST00000355155_ENST00000417892_TCGA-BH-A1F0-01A_VPS13B_chr8_100050794_+_AHI1_chr6_135644462_length(amino acids)=186AA_start in transcript=111_stop in transcript=671
MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSGHIHELRIHVPWTKLGSEPVVITINTMECIL
KLKDGIQVVALYDYTANRSDELTIHRGDIIRVFFKDNEDWWYGSIGKGQEGYFPANHVASETLYQELPPEIKERSPPLSPEEKTKIEKSP

--------------------------------------------------------------
>In-frame_ENST00000441350_ENST00000367800_TCGA-BH-A1F0-01A_VPS13B_chr8_100050794_+_AHI1_chr6_135644462_length(transcript)=2933nt_BP=394nt
ACAGGAGCAGCACTGCCGGCGGGGGCGGGTGCCAGGGACTTGGAGGTGGAGGGGACGCGGCGGTACTCTGGCGTCTTCCGACTTCGACTC
CTTACCTTAAAAGATGCTGGAGTCATATGTAACTCCAATTTTAATGAGCTATGTGAATCGCTACATCAAGAACTTAAAGCCGTCGGATCT
ACAGCTTTCACTATGGGGTGGAGACGTGGTACTCAGCAAGCTCGAGTTAAAGTTGGATGTGCTGGAACAGGAACTGAAATTACCATTCAC
TTTTTTAAGTGGACATATTCATGAATTGAGGATTCATGTACCATGGACAAAACTGGGTTCAGAACCAGTGGTAATTACCATCAATACTAT
GGAATGCATTTTGAAACTTAAGGATGGGATACAGGTAGTGGCTCTTTATGACTACACAGCGAATCGATCAGATGAACTAACCATCCATCG
CGGAGACATTATCCGAGTGTTTTTCAAAGATAATGAAGACTGGTGGTATGGCAGCATAGGAAAGGGACAGGAAGGTTATTTTCCAGCTAA
TCATGTGGCTAGTGAAACACTGTATCAAGAACTGCCTCCTGAGATAAAGGAGCGATCCCCTCCTTTAAGCCCTGAGGAAAAAACTAAAAT
AGAAAAATCTCCAGCTCCTCAAAAGCAATCAATCAATAAGAACAAGTCCCAGGACTTCAGACTAGGCTCAGAATCTATGACACATTCTGA
AATGAGAAAAGAACAGAGCCATGAGGACCAAGGACACATAATGGATACACGGATGAGGAAGAACAAGCAAGCAGGCAGAAAAGTCACTCT
AATAGAGTAAAGAATTGAAGAAAAGTTAAGAGCTGCCGAAATGCACAGAGGTGAAAATGACAAACCAAATGGAATTTCTCTTCAGAGTTC
AGAATTTTCAGATACTAAGGAGGAAGAAAGGATCCACTACTTCTTGTTCTTATGAATGACTCTAGAAAAATCAGAATCAAGTTGTGGGTG
GAAAAATCAACGTGGCCTTTGAGTTCAGTTGTTATAAACCATTGTGACTATTGTTGGTCAAAGTATTGGTACTTATATTGTTAGTAATTG
CATCATAATTACATTACCAGTGTTGGAAAACTAATGAAGAAAACACTGTAATTGCTACTCAGCAAATGTGAATAAAAGGTGTTTGCGTTA
TTAGGATGTCTGTTAAGTAATCATTTAATATTATTATATTGGTAATGGTTGTATGTGTGATGCTATGCCCAGAATATGAAGTATCTGTTT
TTGAAATTCACTTTATTTAAAAGATAAGCAGCTGACTGGGCACGGTGCCTCATGCCTGTAATCCTAGCACCTTGGGAGGCTGAGGCAGGT
GGATCACCTAAGGTCAGGAGTTCAACAACACCAGCCTGACCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATCAGCCGGGTC
TCATGGCAGGCACCTGTAATCCCATCTACTGAGGCAGGAGAATTGCTTGACCCAGGAGGCAGAGGTTGCAGTGAGCCAAGATCACGCCAT
TGCACTCCAGCCTGGGGGACAGAGCAAGACTCTATCTCCAAAAAACAAAAAAGATAAGCAGCTTTAGAATATGGCGCATTCAAAACAGTC
TCAGTAACAAAGACATTAAAAGAAAACAATTTACTTTCTAATTAAAATTTTGTGTTTCTTAAGATCAAATCATATAGGTAACTTCATAGA
CCTAAATTAAAAGTGATTTTTGGCTGGACTGGCAACAATGTTCCCAATGTCTTTACTTTTTAAAAAAGGCTTTTCATATTTAAGCACATA
CCTATTTTGTAGACTTACATTGTTTAATATTTATTTTAATCTTAATATTTTTACATTATTATATTGCATTATTTATTTTTTCTAAGTTCC
AGAATAATAGTGTCATTATTATAGACTATATGTTTTGAAGTTTGATATTATAATGGGATATTCATTTTTTGTTCTTTTCTTGACTCCTTT
CTCAAGTGTGTGATAAGGTCTGCTGATAAAATATTTAACCCCAAGAAAGTGAAAACTAATATAAAATTAGAAAGACCTATCCAAATTAGA
CAGTCAATTCCATTAAAATAAGAAGTGAGAAAAACAATGTTGGGCATTGAGGTGTAAATTTTGCCCAGATGTATACCCAGTGTGAAATAT
CTTCTAATAAAAATATATTTGGCTCTTATCCCTGCACATGTAGAGGCATAAAAATTGGTAAACATGTCCCGCTGTGTAGAACTTTAAAAA
AAAGGCATTTTTGAAAGTGTTGAGTGGCACTGATAACTGGTGAAGCCTACAGCCATCCGCCCAAAAGTCTGTTCTGATGGCACTGAGTTT
TCATTGTTCTGGATGTATAAGTCTGTGTGTCAGGTACAGCTGGGCCCAGCCAGCTTGAGTCACTCTTGTACAAGCTTGTTTTTTTCTGTC
TTGTGAATGCACTTGATAATTTAAAAATAAAAATATCTGTTTCTCTGCAGTTTCAGCTAATAATTTTGAGATATGTGTTGATTTTCTGAT
TGAATCACCAAGAATTTCAACAAGTTTAGAAATAATTTAAGATGAATGAAAAATATGTCAGGGGGAGCTAAGCATTTGCTAAGCTCTTGA
TGTTTATATGAAAAATAAAGGGTTGTTTTTATATTGCAACTACTAAAGAGAAAAATAGCAGTTGAAGCAAACACCAGGAAAATTTGGCTC
TACTGAAAGCCCAGTCCTTTTCCCCTTTGTCTCGCTGACAAAGTAAGACTAGGGTTATGTTCATGAATAGATTAATAAAAGATGTTTCTT
TACCACACAATCTGAGATGAGATGGGGTGGGGGAGATCATGACAGTGCCCTCCAAGCAATAGATCCAGCTGATAATCAAGCAGAAAATCA

>In-frame_ENST00000441350_ENST00000367800_TCGA-BH-A1F0-01A_VPS13B_chr8_100050794_+_AHI1_chr6_135644462_length(amino acids)=238AA_start in transcript=103_stop in transcript=819
MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSGHIHELRIHVPWTKLGSEPVVITINTMECIL
KLKDGIQVVALYDYTANRSDELTIHRGDIIRVFFKDNEDWWYGSIGKGQEGYFPANHVASETLYQELPPEIKERSPPLSPEEKTKIEKSP

--------------------------------------------------------------
>In-frame_ENST00000441350_ENST00000457866_TCGA-BH-A1F0-01A_VPS13B_chr8_100050794_+_AHI1_chr6_135644462_length(transcript)=2479nt_BP=394nt
ACAGGAGCAGCACTGCCGGCGGGGGCGGGTGCCAGGGACTTGGAGGTGGAGGGGACGCGGCGGTACTCTGGCGTCTTCCGACTTCGACTC
CTTACCTTAAAAGATGCTGGAGTCATATGTAACTCCAATTTTAATGAGCTATGTGAATCGCTACATCAAGAACTTAAAGCCGTCGGATCT
ACAGCTTTCACTATGGGGTGGAGACGTGGTACTCAGCAAGCTCGAGTTAAAGTTGGATGTGCTGGAACAGGAACTGAAATTACCATTCAC
TTTTTTAAGTGGACATATTCATGAATTGAGGATTCATGTACCATGGACAAAACTGGGTTCAGAACCAGTGGTAATTACCATCAATACTAT
GGAATGCATTTTGAAACTTAAGGATGGGATACAGGTAGTGGCTCTTTATGACTACACAGCGAATCGATCAGATGAACTAACCATCCATCG
CGGAGACATTATCCGAGTGTTTTTCAAAGATAATGAAGACTGGTGGTATGGCAGCATAGGAAAGGGACAGGAAGGTTATTTTCCAGCTAA
TCATGTGGCTAGTGAAACACTGTATCAAGAACTGCCTCCTGAGATAAAGGAGCGATCCCCTCCTTTAAGCCCTGAGGAAAAAACTAAAAT
AGAAAAATCTCCAGCTCCTCAAAAGCAATCAATCAATAAGAACAAGTCCCAGGACTTCAGACTAGGCTCAGAATCTATGACACATTCTGA
AATGAGAAAAGAACAGAGCCATGAGGACCAAGGACACATAATGGATACACGGATGAGGAAGAACAAGCAAGCAGGCAGAAAAGTCACTCT
AATAGAGTAAAGAATTGAAGAAAAGTTAAGAGCTGCCGAAATGCACAGAGGTGAAAATGACAAACCAAATGGAATTTCTCTTCAGAGTTC
AGAATTTTCAGATACTAAGGAGGAAGAAAGGATCCACTACTTCTTGTTCTTATGAATGACTCTAGAAAAATCAGAATCAAGTTGTGGGTG
GAAAAATCAACGTGGCCTTTGAGTTCAGTTGTTATAAACCATTGTGACTATTGTTGGTCAAAGTATTGGTACTTATATTGTTAGTAATTG
CATCATAATTACATTACCAGTGTTGGAAAACTAATGAAGAAAACACTGTAATTGCTACTCAGCAAATGTGAATAAAAGGTGTTTGCGTTA
TTAGGATGTCTGTTAAGTAATCATTTAATATTATTATATTGGTAATGGTTGTATGTGTGATGCTATGCCCAGAATATGAAGTATCTGTTT
TTGAAATTCACTTTATTTAAAAGATAAGCAGCTGACTGGGCACGGTGCCTCATGCCTGTAATCCTAGCACCTTGGGAGGCTGAGGCAGGT
GGATCACCTAAGGTCAGGAGTTCAACAACACCAGCCTGACCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATCAGCCGGGTC
TCATGGCAGGCACCTGTAATCCCATCTACTGAGGCAGGAGAATTGCTTGACCCAGGAGGCAGAGGTTGCAGTGAGCCAAGATCACGCCAT
TGCACTCCAGCCTGGGGGACAGAGCAAGACTCTATCTCCAAAAAACAAAAAAGATAAGCAGCTTTAGAATATGGCGCATTCAAAACAGTC
TCAGTAACAAAGACATTAAAAGAAAACAATTTACTTTCTAATTAAAATTTTGTGTTTCTTAAGATCAAATCATATAGGTAACTTCATAGA
CCTAAATTAAAAGTGATTTTTGGCTGGACTGGCAACAATGTTCCCAATGTCTTTACTTTTTAAAAAAGGCTTTTCATATTTAAGCACATA
CCTATTTTGTAGACTTACATTGTTTAATATTTATTTTAATCTTAATATTTTTACATTATTATATTGCATTATTTATTTTTTCTAAGTTCC
AGAATAATAGTGTCATTATTATAGACTATATGTTTTGAAGTTTGATATTATAATGGGATATTCATTTTTTGTTCTTTTCTTGACTCCTTT
CTCAAGTGTGTGATAAGGTCTGCTGATAAAATATTTAACCCCAAGAAAGTGAAAACTAATATAAAATTAGAAAGACCTATCCAAATTAGA
CAGTCAATTCCATTAAAATAAGAAGTGAGAAAAACAATGTTGGGCATTGAGGTGTAAATTTTGCCCAGATGTATACCCAGTGTGAAATAT
CTTCTAATAAAAATATATTTGGCTCTTATCCCTGCACATGTAGAGGCATAAAAATTGGTAAACATGTCCCGCTGTGTAGAACTTTAAAAA
AAAGGCATTTTTGAAAGTGTTGAGTGGCACTGATAACTGGTGAAGCCTACAGCCATCCGCCCAAAAGTCTGTTCTGATGGCACTGAGTTT
TCATTGTTCTGGATGTATAAGTCTGTGTGTCAGGTACAGCTGGGCCCAGCCAGCTTGAGTCACTCTTGTACAAGCTTGTTTTTTTCTGTC

>In-frame_ENST00000441350_ENST00000457866_TCGA-BH-A1F0-01A_VPS13B_chr8_100050794_+_AHI1_chr6_135644462_length(amino acids)=238AA_start in transcript=103_stop in transcript=819
MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSGHIHELRIHVPWTKLGSEPVVITINTMECIL
KLKDGIQVVALYDYTANRSDELTIHRGDIIRVFFKDNEDWWYGSIGKGQEGYFPANHVASETLYQELPPEIKERSPPLSPEEKTKIEKSP

--------------------------------------------------------------
>In-frame_ENST00000441350_ENST00000417892_TCGA-BH-A1F0-01A_VPS13B_chr8_100050794_+_AHI1_chr6_135644462_length(transcript)=1957nt_BP=394nt
ACAGGAGCAGCACTGCCGGCGGGGGCGGGTGCCAGGGACTTGGAGGTGGAGGGGACGCGGCGGTACTCTGGCGTCTTCCGACTTCGACTC
CTTACCTTAAAAGATGCTGGAGTCATATGTAACTCCAATTTTAATGAGCTATGTGAATCGCTACATCAAGAACTTAAAGCCGTCGGATCT
ACAGCTTTCACTATGGGGTGGAGACGTGGTACTCAGCAAGCTCGAGTTAAAGTTGGATGTGCTGGAACAGGAACTGAAATTACCATTCAC
TTTTTTAAGTGGACATATTCATGAATTGAGGATTCATGTACCATGGACAAAACTGGGTTCAGAACCAGTGGTAATTACCATCAATACTAT
GGAATGCATTTTGAAACTTAAGGATGGGATACAGGTAGTGGCTCTTTATGACTACACAGCGAATCGATCAGATGAACTAACCATCCATCG
CGGAGACATTATCCGAGTGTTTTTCAAAGATAATGAAGACTGGTGGTATGGCAGCATAGGAAAGGGACAGGAAGGTTATTTTCCAGCTAA
TCATGTGGCTAGTGAAACACTGTATCAAGAACTGCCTCCTGAGATAAAGGAGCGATCCCCTCCTTTAAGCCCTGAGGAAAAAACTAAAAT
AGAAAAATCTCCAGCTCCTCAAAAGGTAAAATAAAACAAAACAGCTCACAGAGACACCTCCTTCTTCCCCCTGCTTCTGCCTCCATGAGT
AACTACCTATATGACGTGCTGCTGCTGAGACCAAGGAATGAATAGTGCCAAATCTTGCTGAAGAATGATCTTGCAGAAATCTGATTGTGA
AGAAGGAAATCTAAAAAGGCCAAACAAGCTTCAGTAGAGATAACACCAGGAAAGCAGTTACTCAAACAAGACTGAAAGAGAAGCAATCAA
TCAATAAGAACAAGTCCCAGGACTTCAGACTAGGCTCAGAATCTATGACACATTCTGAAATGAGAAAAGAACAGAGCCATGAGGACCAAG
GACACATAATGGATACACGGATGAGGAAGAACAAGCAAGCAGGCAGAAAAGTCACTCTAATAGAGTGTGCCAGCTGTCACTTTTCTCAGG
AGTGGTCGATGGAGTTGACTGCTACCTTAACCAGATTTGCCATCGTTCTGAAACTGCCGTGTGTTTTCTAAGGACAACCAGGTGTTAAGC
CTTTCTCTTTAGAAGAAGGACAGTAACCTTTCTGTTAAAGAATTGAAGAAAAGTTAAGAGCTGCCGAAATGCACAGAGGTGAAAATGACA
AACCAAATGGAATTTCTCTTCAGAGTTCAGAATTTTCAGATACTAAGGAGGAAGAAAGGATCCACTACTTCTTGTTCTTATGAATGACTC
TAGAAAAATCAGAATCAAGTTGTGGGTGGAAAAATCAACGTGGCCTTTGAGTTCAGTTGTTATAAACCATTGTGACTATTGTTGGTCAAA
GTATTGGTACTTATATTGTTAGTAATTGCATCATAATTACATTACCAGTGTTGGAAAACTAATGAAGAAAACACTGTAATTGCTACTCAG
CAAATGTGAATAAAAGGTGTTTGCGTTATTAGGATGTCTGTTAAGTAATCATTTAATATTATTATATTGGTAATGGTTGTATGTGTGATG
CTATGCCCAGAATATGAAGTATCTGTTTTTGAAATTCACTTTATTTAAAAGATAAGCAGCTGACTGGGCACGGTGCCTCATGCCTGTAAT
CCTAGCACCTTGGGAGGCTGAGGCAGGTGGATCACCTAAGGTCAGGAGTTCAACAACACCAGCCTGACCAACATGGTGAAACCCCATCTC
TACTAAAAATACAAAAATCAGCCGGGTCTCATGGCAGGCACCTGTAATCCCATCTACTGAGGCAGGAGAATTGCTTGACCCAGGAGGCAG

>In-frame_ENST00000441350_ENST00000417892_TCGA-BH-A1F0-01A_VPS13B_chr8_100050794_+_AHI1_chr6_135644462_length(amino acids)=186AA_start in transcript=103_stop in transcript=663
MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSGHIHELRIHVPWTKLGSEPVVITINTMECIL
KLKDGIQVVALYDYTANRSDELTIHRGDIIRVFFKDNEDWWYGSIGKGQEGYFPANHVASETLYQELPPEIKERSPPLSPEEKTKIEKSP

--------------------------------------------------------------

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Fusion Gene PPI Analysis for VPS13B-AHI1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneAHI1chr8:100050794chr6:135644462ENST00000327035023141_43401054.0HAP1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneAHI1chr8:100050794chr6:135644462ENST000003678002127141_4341055.01197.0HAP1
TgeneAHI1chr8:100050794chr6:135644462ENST000004578662228141_4341055.01197.0HAP1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for VPS13B-AHI1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for VPS13B-AHI1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneVPS13BC0265223Cohen syndrome10CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
HgeneVPS13BC1854061Cutis Verticis Gyrata, Retinitis Pigmentosa, and Sensorineural Deafness8CLINGEN
TgeneAHI1C1837713JOUBERT SYNDROME 37CTD_human;GENOMICS_ENGLAND;UNIPROT
TgeneAHI1C0004352Autistic Disorder1CTD_human
TgeneAHI1C0007760Cerebellar Diseases1CTD_human
TgeneAHI1C0020796Profound Mental Retardation1CTD_human
TgeneAHI1C0025363Mental Retardation, Psychosocial1CTD_human
TgeneAHI1C0035304Retinal Degeneration1CTD_human
TgeneAHI1C0036341Schizophrenia1CTD_human
TgeneAHI1C0152427Polydactyly1GENOMICS_ENGLAND
TgeneAHI1C0162538Immunoglobulin A deficiency (disorder)1CTD_human
TgeneAHI1C0431399Familial aplasia of the vermis1GENOMICS_ENGLAND;ORPHANET
TgeneAHI1C0917816Mental deficiency1CTD_human
TgeneAHI1C3553264JOUBERT SYNDROME 171GENOMICS_ENGLAND
TgeneAHI1C3714756Intellectual Disability1CTD_human
TgeneAHI1C4274118Joubert syndrome with ocular defect1ORPHANET
TgeneAHI1C4551568Joubert syndrome 11ORPHANET