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![]() | Fusion Gene Summary |
![]() | Fusion Gene ORF analysis |
![]() | Fusion Genomic Features |
![]() | Fusion Protein Features |
![]() | Fusion Gene Sequence |
![]() | Fusion Gene PPI analysis |
![]() | Related Drugs |
![]() | Related Diseases |
Fusion gene:VPS53-LRP1B (FusionGDB2 ID:97812) |
Fusion Gene Summary for VPS53-LRP1B |
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Fusion gene information | Fusion gene name: VPS53-LRP1B | Fusion gene ID: 97812 | Hgene | Tgene | Gene symbol | VPS53 | LRP1B | Gene ID | 55275 | 53353 |
Gene name | VPS53 subunit of GARP complex | LDL receptor related protein 1B | |
Synonyms | HCCS1|PCH2E|hVps53L|pp13624 | LRP-1B|LRP-DIT|LRPDIT | |
Cytomap | 17p13.3 | 2q22.1-q22.2 | |
Type of gene | protein-coding | protein-coding | |
Description | vacuolar protein sorting-associated protein 53 homologVPS53, GARP complex subunit | low-density lipoprotein receptor-related protein 1BLRP-deleted in tumorslow density lipoprotein receptor related protein-deleted in tumorlow density lipoprotein receptor-related protein 1Blow density lipoprotein-related protein 1B (deleted in tumors) | |
Modification date | 20200313 | 20200313 | |
UniProtAcc | . | Q9NZR2 | |
Ensembl transtripts involved in fusion gene | ENST00000437048, ENST00000574029, ENST00000576149, ENST00000446250, ENST00000291074, ENST00000571805, ENST00000401468, | ENST00000389484, ENST00000486364, | |
Fusion gene scores | * DoF score | 18 X 15 X 14=3780 | 12 X 13 X 5=780 |
# samples | 24 | 13 | |
** MAII score | log2(24/3780*10)=-3.97727992349992 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(13/780*10)=-2.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
Context | PubMed: VPS53 [Title/Abstract] AND LRP1B [Title/Abstract] AND fusion [Title/Abstract] | ||
Most frequent breakpoint | VPS53(463666)-LRP1B(142012210), # samples:1 | ||
Anticipated loss of major functional domain due to fusion event. | VPS53-LRP1B seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF. VPS53-LRP1B seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF. VPS53-LRP1B seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF. VPS53-LRP1B seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF. |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
![]() * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
![]() * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChimerDB4 | UCEC | TCGA-AJ-A3NF-01A | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - |
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Fusion Gene ORF analysis for VPS53-LRP1B |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
Frame-shift | ENST00000437048 | ENST00000389484 | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - |
5CDS-intron | ENST00000437048 | ENST00000486364 | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - |
intron-3CDS | ENST00000574029 | ENST00000389484 | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - |
intron-intron | ENST00000574029 | ENST00000486364 | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - |
5UTR-3CDS | ENST00000576149 | ENST00000389484 | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - |
5UTR-intron | ENST00000576149 | ENST00000486364 | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - |
In-frame | ENST00000446250 | ENST00000389484 | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - |
5CDS-intron | ENST00000446250 | ENST00000486364 | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - |
Frame-shift | ENST00000291074 | ENST00000389484 | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - |
5CDS-intron | ENST00000291074 | ENST00000486364 | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - |
Frame-shift | ENST00000571805 | ENST00000389484 | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - |
5CDS-intron | ENST00000571805 | ENST00000486364 | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - |
Frame-shift | ENST00000401468 | ENST00000389484 | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - |
5CDS-intron | ENST00000401468 | ENST00000486364 | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - |
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Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
ENST00000446250 | VPS53 | chr17 | 463666 | - | ENST00000389484 | LRP1B | chr2 | 142012210 | - | 17169 | 1949 | 1927 | 15405 | 4492 |
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Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
ENST00000446250 | ENST00000389484 | VPS53 | chr17 | 463666 | - | LRP1B | chr2 | 142012210 | - | 0.00146098 | 0.998539 |
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Fusion Genomic Features for VPS53-LRP1B |
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Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
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Fusion Protein Features for VPS53-LRP1B |
![]() FGviewer for the breakpoints of chr17:463666-chr2:142012210 - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. |
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Hgene | Tgene |
. | LRP1B |
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes. | FUNCTION: Potential cell surface proteins that bind and internalize ligands in the process of receptor-mediated endocytosis. |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Hgene | VPS53 | chr17:463666 | chr2:142012210 | ENST00000291074 | - | 14 | 18 | 97_138 | 539.0 | 671.0 | Coiled coil | Ontology_term=ECO:0000255 |
Hgene | VPS53 | chr17:463666 | chr2:142012210 | ENST00000437048 | - | 15 | 22 | 97_138 | 568.0 | 833.0 | Coiled coil | Ontology_term=ECO:0000255 |
Hgene | VPS53 | chr17:463666 | chr2:142012210 | ENST00000571805 | - | 15 | 19 | 97_138 | 568.0 | 700.0 | Coiled coil | Ontology_term=ECO:0000255 |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1005_1043 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 7 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1052_1089 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 8 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1094_1132 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 9 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1135_1174 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 10 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 116_154 | 114.33333333333333 | 4600.0 | Domain | EGF-like 1 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1174_1213 | 114.33333333333333 | 4600.0 | Domain | EGF-like 5 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1214_1253 | 114.33333333333333 | 4600.0 | Domain | EGF-like 6 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1527_1570 | 114.33333333333333 | 4600.0 | Domain | EGF-like 7 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 155_194 | 114.33333333333333 | 4600.0 | Domain | EGF-like 2%3B calcium-binding | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1834_1875 | 114.33333333333333 | 4600.0 | Domain | EGF-like 8 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2143_2183 | 114.33333333333333 | 4600.0 | Domain | EGF-like 9 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2464_2504 | 114.33333333333333 | 4600.0 | Domain | EGF-like 10 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2509_2548 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 11 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2551_2587 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 12 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2590_2626 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 13 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2629_2675 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 14 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2681_2717 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 15 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2719_2757 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 16 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2760_2800 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 17 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2804_2841 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 18 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2844_2885 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 19 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2890_2926 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 20 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2927_2967 | 114.33333333333333 | 4600.0 | Domain | EGF-like 11 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2968_3008 | 114.33333333333333 | 4600.0 | Domain | EGF-like 12%3B calcium-binding | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3273_3314 | 114.33333333333333 | 4600.0 | Domain | EGF-like 13 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3316_3353 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 21 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3356_3392 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 22 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3395_3432 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 23 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3435_3472 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 24 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3475_3511 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 25 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3514_3550 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 26 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3552_3588 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 27 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3593_3629 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 28 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3631_3668 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 29 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3673_3711 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 30 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3714_3752 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 31 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3761_3797 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 32 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3801_3843 | 114.33333333333333 | 4600.0 | Domain | EGF-like 14 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3844_3881 | 114.33333333333333 | 4600.0 | Domain | EGF-like 15 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 4171_4208 | 114.33333333333333 | 4600.0 | Domain | EGF-like 16 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 4213_4249 | 114.33333333333333 | 4600.0 | Domain | EGF-like 17 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 4249_4285 | 114.33333333333333 | 4600.0 | Domain | EGF-like 18 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 4285_4321 | 114.33333333333333 | 4600.0 | Domain | EGF-like 19 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 4321_4357 | 114.33333333333333 | 4600.0 | Domain | EGF-like 20 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 4357_4392 | 114.33333333333333 | 4600.0 | Domain | EGF-like 21 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 4390_4427 | 114.33333333333333 | 4600.0 | Domain | EGF-like 22 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 471_517 | 114.33333333333333 | 4600.0 | Domain | EGF-like 3 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 794_834 | 114.33333333333333 | 4600.0 | Domain | EGF-like 4 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 844_882 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 3 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 885_923 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 4 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 926_963 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 5 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 966_1003 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 6 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 4492_4495 | 114.33333333333333 | 4600.0 | Motif | Endocytosis signal | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 4559_4562 | 114.33333333333333 | 4600.0 | Motif | Endocytosis signal | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1300_1346 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 8 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1347_1389 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 9 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1390_1436 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 10 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1437_1480 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 11 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1481_1522 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 12 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1618_1660 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 13 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1661_1704 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 14 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1705_1744 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 15 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1745_1787 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 16 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1922_1964 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 17 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 1965_2007 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 28 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2008_2051 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 19 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2052_2095 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 20 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2239_2280 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 21 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2281_2329 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 22 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2330_2374 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 23 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2375_2416 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 24 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 2417_2459 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 25 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 295_337 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 1 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3055_3098 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 26 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3099_3141 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 27 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3142_3185 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 28 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3186_3224 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 29 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3225_3268 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 30 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 338_381 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 2 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 382_425 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 3 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3933_3980 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 31 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 3981_4038 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 32 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 4039_4082 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 33 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 4083_4127 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 34 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 568_610 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 4 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 611_656 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 5 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 657_706 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 6 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 707_750 | 114.33333333333333 | 4600.0 | Repeat | Note=LDL-receptor class B 7 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 4468_4599 | 114.33333333333333 | 4600.0 | Topological domain | Cytoplasmic | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 4445_4467 | 114.33333333333333 | 4600.0 | Transmembrane | Helical |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 31_70 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 1 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 76_114 | 114.33333333333333 | 4600.0 | Domain | LDL-receptor class A 2 | |
Tgene | LRP1B | chr17:463666 | chr2:142012210 | ENST00000389484 | 2 | 91 | 25_4444 | 114.33333333333333 | 4600.0 | Topological domain | Extracellular |
Top |
Fusion Gene Sequence for VPS53-LRP1B |
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>In-frame_ENST00000446250_ENST00000389484_TCGA-AJ-A3NF-01A_VPS53_chr17_463666_-_LRP1B_chr2_142012210_length(transcript)=17169nt_BP=1949nt GAAGTGCCGGAGCGGCTGACAGAGCGGCTGACGGAGCCGGGCTCACCAGGTCGCTGCCGCGAGGGAGTTGCTGTGCTGGGGCCTGGGTGG CGGCTGGAGGCCTGAGTTGGGCTCGCGGCGGGGGTCGGCAGGGGGCCGGGTGGCGGAATGATGGAGGAGGAGGAACTGGAGTTCGTGGAG GAGCTGGAAGCCGTGCTGCAGCTCACGCCCGAGGTGCAGCTGGCCATCGAGCAGGTGTTTCCAAGCCAGGACCCTCTAGATCGAGCAGAT TTCAATGCTGTTGAGTATATCAATACCCTGTTCCCAACCGAGCAATCTCTGGCGAACATAGACGAAGTCGTGAACAAAATTAGGCTGAAA ATAAGGAGACTGGATGACAATATTCGAACTGTTGTAAGAGGTCAGACGAACGTGGGGCAGGATGGACGGCAAGCGCTTGAAGAGGCTCAG AAAGCTATCCAACAACTCTTTGGCAAAATCAAAGATATCAAAGACAAAGCTGAAAAATCAGAGCAAATGGTGAAAGAAATCACCCGTGAT ATTAAGCAATTAGATCACGCCAAACGCCACCTGACCACCTCAATCACCACACTGAACCACCTGCACATGCTGGCAGGAGGTGTCGACTCC CTCGAAGCCATGACCAGGCGAAGACAATACGGAGAAGTTGCTAATCTCCTTCAGGGTGTGATGAATGTCCTGGAGCACTTCCACAAGTAT ATGGGGATTCCGCAGATCCGGCAGCTTTCCGAAAGGAAACCCAAAACACTGCAGCTGCATGGATTGAACTGGACGTGATGTGAAATGAAA TAAGCCAGACACGGGAAGACAGATTCCTCATGTTCTCACTCATAGTGAAGGCTGCACAGACTGAGTTAGGACAGCAAATCCTGGCAGATT TTGAAGAAGCGTTTCCTTCCCAGGGCACCAAGAGACCAGGAGGACCCAGCAATGTTCTACGAGATGCATGTCTGGTTGCTAATATTCTAG ATCCCAGGATCAAACAGGAAATCATCAAAAAGTTTATTAAACAGCATCTGTCAGAGTATCTGGTACTTTTTCAAGAAAACCAAGATGTTG CCTGGCTGGACAAAATCGACAGACGCTATGCCTGGATAAAACGCCAGCTTGTGGACTATGAGGAGAAATACGGCCGCATGTTTCCACGTG AGTGGTGCATGGCTGAGAGGATTGCGGTGGAATTTTGCCATGTGACAAGGGCAGAACTTGCCAAGATTATGCGTACCAGAGCGAAGGAAA TTGAAGTGAAATTGCTTCTTTTTGCTATTCAAAGAACAACTAACTTTGAGGGGTTTCTTGCAAAACGCTTCTCCGGCTGCACCCTGACCG ATGGGACCCTGAAAAAGCTTGAGTCTCCACCCCCATCTACCAATCCCTTCCTGGAAGATGAGCCAACACCAGAGATGGAGGAACTGGCAA CGGAGAAAGGAGATTTAGATCAACCAAAGAAGCCTAAAGCCCCAGACAATCCATTTCATGGCATTGTTTCCAAGTGTTTTGAGCCTCATC TCTACGTGTATATCGAATCCCAAGACAAGAACCTCGGAGAGCTGATAGATCGGTTTGTGGCTGATTTCAAAGCCCAGGGGCCACCTAAGC CCAACACTGATGAAGGGGGTGCCGTGCTCCCCAGCTGCGCCGACCTCTTTGTCTACTACAAGAAGTGCATGGTGCAATGCTCTCAGCTCA GTACTGGGGAGCCCATGATCGCCCTGACCACCATTTTCCAGAAGTACCTCCGAGAATACGCCTGGAAAATCCTCTCTGGCAACCTGCCCA AAACCACAACCAGCAGTGGAGGACTGACTATCAGCAGCCTCCTCAAGGAAAAGGAGGGCTCAGAAGTAGCCAAGTTCACTCTGGAGGAGC TCTGCCTCATCTGTAACATCCTGAGCACGGCAGAGTACTGTCTGGCCACCACCCAGCAGAACTGTTATCCAATTGCCAACAGCTGAATTG TCAGTATAAATGTACAATGGTCAGAAATAGTACAAGATGTTACTGTGAGGATGGATTCGAAATAACAGAAGATGGGAGAAGCTGTAAAGA TCAAGATGAATGTGCTGTTTATGGTACATGCAGCCAGACCTGCAGAAACACACATGGATCCTACACTTGCAGTTGTGTGGAAGGCTACCT AATGCAGCCAGACAACAGATCTTGCAAGGCTAAAATTGAACCTACAGATAGACCACCTATACTATTAATTGCAAATTTTGAAACAATTGA GGTTTTCTATCTTAATGGAAGTAAAATGGCAACTCTAAGCTCAGTCAATGGAAATGAAATTCATACTCTGGATTTTATTTATAATGAAGA TATGATTTGTTGGATTGAATCAAGAGAATCTTCAAATCAACTCAAATGTATCCAGATAACAAAAGCAGGAGGATTAACAGATGAATGGAC AATCAATATTCTTCAATCCTTCCACAATGTGCAACAAATGGCGATTGACTGGCTCACTCGAAATCTCTATTTTGTGGACCATGTCGGTGA CCGGATCTTTGTTTGTAATTCCAACGGTTCTGTATGTGTCACCCTGATTGATCTGGAGCTTCACAATCCTAAAGCAATAGCAGTAGATCC AATAGCAGGAAAACTTTTCTTTACTGACTACGGGAATGTCGCCAAAGTGGAGAGATGTGACATGGATGGGATGAACCGAACAAGGATAAT TGATTCAAAGACAGAGCAGCCAGCTGCACTGGCACTAGACCTAGTCAACAAATTGGTTTACTGGGTAGATCTTTACTTGGACTATGTGGG AGTAGTGGACTATCAAGGAAAAAATAGACACACTGTCATTCAAGGCAGACAAGTTAGACATCTTTATGGTATAACTGTGTTTGAAGATTA TTTGTATGCAACCAATTCTGATAACTACAATATCGTAAGGATAAACCGATTTAATGGGACTGATATTCACTCATTAATTAAAATTGAGAA TGCTTGGGGAATCCGAATTTATCAAAAAAGAACTCAACCAACAGTCAGAAGCCATGCATGTGAAGTCGATCCATATGGAATGCCAGGGGG CTGTTCACACATCTGTCTACTCAGCAGCAGTTACAAAACTCGGACTTGTCGCTGCAGGACTGGCTTCAACTTGGGAAGTGATGGCAGGTC ATGCAAAAGACCAAAGAATGAGTTGTTCCTCTTTTATGGGAAAGGACGCCCAGGAATTGTTAGAGGAATGGACTTGAATACCAAGATAGC TGATGAATACATGATCCCCATAGAAAATCTGGTAAACCCTCGTGCTTTAGACTTTCACGCAGAAACCAATTACATCTACTTTGCTGACAC CACCAGTTTCCTAATTGGCCGGCAGAAGATAGATGGCACAGAGAGAGAAACCATCCTGAAAGATGATCTGGATAATGTAGAGGGCATTGC TGTGGACTGGATTGGAAATAATCTTTACTGGACCAATGATGGCCATAGGAAAACCATTAATGTGGCCAGGCTGGAAAAAGCTTCTCAGAG TCGGAAGACTCTTTTAGAGGGTGAAATGTCTCATCCCAGAGGAATTGTGGTGGATCCAGTTAATGGTTGGATGTATTGGACAGACTGGGA GGAAGATGAAATAGATGACAGCGTGGGAAGGATTGAGAAGGCCTGGATGGATGGATTCAATCGGCAGATTTTTGTGACTTCAAAGATGCT GTGGCCAAACGGTTTAACTCTGGACTTTCACACCAACACATTATACTGGTGTGATGCCTATTACGATCATATTGAAAAAGTATTTTTGAA TGGGACTCACAGGAAGATTGTTTACAGTGGGAGAGAGTTGAACCACCCTTTCGGACTGTCGCATCATGGAAATTATGTGTTCTGGACTGA TTATATGAATGGTTCCATTTTTCAACTAGATTTGATAACAAGTGAGGTGACATTGCTGAGGCATGAAAGACCACCCCTATTTGGGCTTCA GATTTATGATCCACGAAAGCAACAAGGTGACAATATGTGCCGAGTAAATAATGGGGGCTGTAGTACACTTTGCTTGGCTATCCCAGGAGG CCGGGTGTGTGCTTGTGCCGATAATCAACTTTTGGATGAAAATGGGACAACTTGCACATTTAATCCTGGAGAAGCACTACCTCACATATG TAAAGCTGGAGAGTTTCGCTGCAAAAACAGACACTGTATCCAAGCTCGGTGGAAATGTGATGGCGACGATGACTGCCTAGACGGAAGCGA TGAGGATTCAGTAAACTGCTTCAATCATAGCTGTCCTGATGATCAGTTTAAATGCCAGAATAATCGCTGCATCCCCAAGAGATGGCTTTG TGATGGAGCTAATGACTGTGGGAGCAATGAAGATGAATCCAATCAAACTTGCACAGCCAGAACATGCCAGGTAGACCAGTTTTCTTGCGG AAATGGGCGTTGCATTCCCAGAGCATGGCTGTGTGACAGGGAAGACGACTGTGGTGACCAGACAGATGAAATGGCATCTTGTGAATTCCC AACTTGTGAGCCACTAACCCAATTCGTATGCAAAAGTGGAAGATGCATTAGCAGCAAATGGCACTGCGACTCTGATGACGACTGTGGGGA CGGGAGTGATGAGGTGGGCTGTGTTCACTCTTGCTTTGATAATCAGTTCAGATGTTCCAGTGGCAGATGCATCCCAGGCCACTGGGCCTG TGATGGTGACAATGACTGTGGGGACTTCAGTGATGAAGCCCAGATCAATTGTACTAAAGAAGAGATTCATTCTCCTGCTGGTTGTAACGG AAATGAATTTCAGTGCCACCCTGATGGTAATTGCGTTCCTGATTTGTGGCGCTGTGATGGAGAAAAAGACTGTGAAGATGGTAGTGATGA AAAAGGTTGCAATGGTACCATACGATTGTGTGACCACAAAACCAAGTTTTCCTGTTGGAGTACAGGGAGATGCATCAACAAAGCATGGGT GTGTGATGGAGATATTGATTGCGAAGATCAGTCAGATGAAGATGACTGTGACAGTTTCTTGTGTGGACCACCCAAGCATCCTTGTGCTAA TGACACCTCAGTCTGCCTGCAGCCAGAGAAACTCTGCAATGGGAAAAAGGATTGTCCTGATGGCTCTGATGAAGGCTATCTCTGTGATGA GTGTTCGCTGAACAATGGAGGCTGTAGCAACCACTGTTCTGTTGTTCCTGGAAGAGGAATTGTCTGTTCCTGCCCTGAAGGACTTCAACT CAACAAAGACAATAAAACATGTGAAATTGTGGATTATTGTAGCAATCATCTAAAGTGCAGCCAAGTATGTGAGCAGCACAAGCACACAGT CAAGTGCTCATGTTATGAAGGTTGGAAGCTGGATGTAGACGGTGAAAGTTGTACAAGTGTTGATCCTTTTGAAGCATTCATCATCTTTTC TATTCGTCATGAGATCAGAAGGATTGATCTTCACAAAAGAGACTATAGTCTACTTGTTCCTGGATTGAGAAACACAATAGCACTTGATTT TCACTTCAATCAAAGTTTACTTTATTGGACAGATGTTGTAGAAGACAGAATATACCGGGGAAAGCTTTCTGAAAGTGGAGGTGTCAGTGC CATTGAAGTGGTTGTGGAGCATGGCCTGGCTACTCCAGAAGGCCTGACAGTCGACTGGATAGCAGGAAACATATACTGGATAGACAGCAA TCTGGACCAAATCGAAGTGGCCAAACTAGATGGCTCCCTAAGAACTACACTAATAGCAGGAGCCATGGAACACCCCAGGGCCATTGCTTT GGACCCAAGATATGGAATTCTTTTCTGGACAGACTGGGATGCAAATTTTCCTCGCATTGAATCTGCCTCTATGAGTGGTGCTGGGAGAAA AACCATCTATAAAGACATGAAAACTGGGGCTTGGCCTAATGGACTAACTGTGGACCACTTTGAGAAAAGGATAGTGTGGACAGACGCCAG GTCAGATGCTATTTATTCAGCCCTCTATGATGGAACAAACATGATAGAAATCATCCGAGGTCATGAATACCTTTCCCATCCCTTTGCTGT GTCTCTATATGGGAGTGAAGTCTACTGGACAGACTGGAGGACCAACACATTGTCCAAAGCCAATAAGTGGACAGGGCAGAATGTCAGTGT GATTCAGAAAACCAGTGCACAGCCATTTGACCTTCAGATATACCATCCCAGTCGCCAGCCACAGGCTCCCAATCCTTGTGCAGCTAATGA TGGCAAAGGCCCCTGCTCTCACATGTGTCTAATCAATCACAATAGGAGTGCTGCCTGTGCGTGCCCCCACTTGATGAAGCTTTCTTCAGA CAAGAAGACCTGCTATGAAATGAAAAAATTTCTTCTTTATGCAAGACGTTCTGAAATCAGAGGAGTGGATATTGACAATCCATACTTTAA CTTCATCACGGCATTTACAGTCCCTGATATTGATGACGTTACTGTGATAGACTTCGATGCATCTGAGGAACGTTTATACTGGACAGATAT TAAAACACAAACCATTAAACGAGCTTTTATTAACGGAACTGGGTTAGAAACTGTTATTTCAAGAGATATTCAGAGTATCAGAGGGCTAGC AGTGGATTGGGTGTCACGTAATTTATACTGGATTAGCTCAGAATTTGATGAAACGCAAATTAATGTGGCAAGGCTAGATGGCTCTTTGAA AACCTCAATTATCCATGGAATCGATAAGCCACAGTGTCTTGCAGCTCACCCAGTCAGGGGAAAACTCTACTGGACCGATGGAAACACAAT TAACATGGCAAATATGGATGGCAGTAATAGCAAGATTCTGTTTCAGAATCAGAAGGAGCCAGTTGGTCTATCGATAGACTATGTGGAAAA CAAGCTTTATTGGATCAGTTCAGGGAATGGAACCATAAATAGATGCAACCTGGATGGTGGTAATTTAGAAGTAATCGAGTCAATGAAAGA AGAATTAACAAAAGCTACAGCCCTAACCATCATGGATAAGAAACTGTGGTGGGCAGACCAAAACTTAGCCCAGCTAGGAACCTGCAGCAA AAGAGACGGAAGAAACCCCACCATCCTACGGAATAAGACTTCTGGGGTAGTTCATATGAAAGTCTATGATAAAGAAGCACAGCAAGGCAG CAATTCCTGCCAACTAAACAATGGTGGATGCTCTCAACTTTGTTTACCAACATCTGAAACTACAAGGACTTGTATGTGTACAGTGGGATA TTATCTCCAAAAGAACCGTATGTCATGTCAAGGTATAGAATCATTTCTTATGTACTCTGTTCATGAAGGAATCAGGGGAATACCTCTTGA ACCAAGTGACAAAATGGATGCTTTGATGCCTATATCAGGAACTTCATTTGCCGTGGGAATAGATTTCCATGCAGAAAATGATACCATCTA CTGGACAGACATGGGCTTCAATAAAATTAGCAGAGCTAAAAGAGATCAGACTTGGAAAGAAGATATCATTACCAATGGCTTGGGAAGAGT GGAAGGGATAGCTGTTGACTGGATTGCTGGTAACATATATTGGACAGATCATGGTTTCAACTTAATTGAAGTTGCAAGACTCAATGGTTC TTTCCGTTATGTAATTATTTCCCAAGGCCTGGATCAACCAAGATCTATAGCTGTGCACCCAGAGAAAGGCCTCTTGTTCTGGACTGAATG GGGACAAATGCCCTGTATTGGAAAGGCTCGCTTGGATGGCTCAGAGAAGGTTGTCCTTGTAAGCATGGGAATAGCATGGCCGAATGGCAT CTCCATCGACTATGAGGAAAATAAATTGTACTGGTGTGATGCTCGCACAGACAAGATAGAGAGAATCGACCTTGAGACTGGAGGGAATCG CGAGATGGTGCTGTCAGGAAGCAATGTGGATATGTTTTCAGTTGCAGTCTTTGGGGCTTACATCTACTGGTCTGACAGAGCACATGCAAA CGGGTCTGTCAGAAGGGGCCACAAGAATGATGCCACAGAAACGATAACCATGAGAACCGGCCTTGGAGTCAACCTGAAGGAGGTTAAAAT ATTTAACCGAGTAAGAGAGAAAGGGACCAATGTTTGTGCCAGGGACAATGGTGGCTGTAAGCAACTCTGTCTTTATCGAGGAAATTCCCG GAGAACTTGTGCTTGTGCCCATGGATATTTGGCAGAAGATGGAGTTACTTGCCTGAGGCATGAAGGCTATTTACTGTATTCAGGAAGAAC AATATTAAAAAGTATACATCTTTCTGATGAAACCAATTTAAATTCCCCAATAAGGCCATATGAGAATCCACGTTATTTCAAGAATGTCAT AGCCTTGGCTTTTGACTATAATCAAAGAAGAAAAGGTACCAACCGAATCTTTTACAGTGATGCACACTTTGGAAATATACAGCTTATTAA AGACAACTGGGAAGACAGACAAGTAATTGTTGAAAATGTGGGTTCTGTGGAAGGACTTGCCTATCACAGAGCCTGGGATACACTGTACTG GACAAGCTCTACCACCTCATCCATCACCAGACACACTGTGGACCAGACTCGGCCTGGAGCATTTGACAGGGAAGCTGTCATCACCATGTC AGAAGATGACCATCCACATGTGCTAGCCTTGGATGAATGTCAAAATTTAATGTTTTGGACCAACTGGAATGAACAACATCCAAGTATCAT GAGATCTACTCTGACTGGGAAAAATGCTCAAGTGGTGGTCAGTACAGACATACTCACTCCAAATGGACTTACTATCGACTACCGTGCAGA GAAGCTGTATTTCTCAGATGGCAGTCTAGGAAAAATTGAAAGGTGTGAATACGATGGATCCCAGAGACATGTGATAGTTAAATCTGGGCC AGGGACTTTCCTCAGTTTGGCTGTTTATGACAATTATATATTCTGGTCGGACTGGGGAAGAAGAGCTATACTGCGGTCCAACAAGTACAC AGGAGGAGATACAAAAATTCTTCGTTCCGATATTCCACATCAGCCAATGGGAATCATAGCTGTTGCCAATGACACCAATAGCTGTGAACT TTCTCCATGTGCATTATTGAATGGAGGCTGCCATGACTTGTGCCTTTTAACTCCCAATGGGAGAGTGAATTGTTCCTGCAGAGGGGACCG AATATTGCTAGAGGACAACAGATGTGTGACTAAAAATTCCTCCTGCAACGCTTATTCGGAGTTTGAATGTGGAAATGGTGAGTGCATTGA CTACCAGCTCACCTGTGATGGCATTCCTCACTGTAAAGATAAATCAGATGAAAAACTGCTCTACTGTGAAAACAGAAGCTGTCGAAGAGG CTTCAAGCCATGCTATAATCGCCGCTGCATTCCTCATGGCAAGTTATGTGATGGAGAAAATGACTGCGGAGACAACTCTGATGAATTAGA TTGTAAAGTTTCAACCTGTGCCACGGTTGAGTTCCGCTGTGCAGATGGGACTTGTATTCCAAGATCAGCACGATGCAACCAGAACATAGA TTGTGCAGATGCTTCAGATGAAAAGAACTGCAATAACACAGACTGCACACATTTCTATAAGCTTGGAGTGAAAACCACAGGGTTCATAAG ATGTAATTCTACCTCACTGTGTGTTCTGCCAACCTGGATATGCGACGGGTCTAATGACTGTGGAGACTATTCAGATGAATTAAAGTGCCC AGTTCAAAACAAACACAAATGTGAAGAAAATTATTTTAGTTGTCCTAGTGGAAGATGCATTTTGAATACCTGGATATGCGATGGTCAGAA AGATTGTGAGGATGGACGTGATGAATTCCACTGTGATTCTTCTTGCTCTTGGAACCAATTTGCTTGTTCCGCACAAAAATGTATTTCTAA GCATTGGATTTGTGATGGAGAAGATGACTGTGGGGATGGGTTAGATGAAAGTGACAGCATTTGTGGTGCCATAACCTGTGCTGCTGACAT GTTCAGCTGCCAGGGCTCTCGTGCCTGCGTGCCCCGACATTGGCTTTGTGATGGTGAAAGGGACTGTCCAGATGGAAGCGATGAGCTTTC CACAGCAGGCTGCGCTCCCAATAATACATGTGATGAAAATGCTTTCATGTGCCATAATAAAGTATGCATTCCCAAGCAATTTGTTTGTGA CCATGATGACGACTGTGGAGATGGCTCTGATGAGTCACCGCAGTGTGGATATCGACAGTGTGGTACAGAAGAATTTAGTTGTGCTGATGG GCGGTGTCTTCTAAATACTCAATGGCAGTGTGATGGAGACTTTGACTGTCCTGACCATTCTGATGAAGCACCTTTAAACCCAAAGTGTAA AAGTGCAGAACAGTCATGCAACAGTTCATTTTTTATGTGCAAAAATGGCAGGTGCATTCCCAGTGGAGGTCTTTGCGACAATAAGGATGA CTGTGGCGATGGTTCAGATGAGAGAAACTGCCATATAAATGAATGTTTGAGTAAGAAAGTCAGTGGATGTTCTCAAGACTGTCAAGACCT TCCGGTCAGTTATAAGTGCAAATGCTGGCCTGGATTCCAACTGAAGGATGACGGCAAAACATGTGTAGACATTGATGAATGCTCTTCAGG CTTTCCCTGTAGCCAGCAATGCATCAATACATACGGGACTTACAAGTGCCTCTGTACAGATGGGTATGAAATACAACCTGATAACCCAAA TGGCTGCAAATCGCTCTCAGATGAAGAACCTTTTTTAATTCTTGCTGATCATCATGAGATAAGGAAAATTAGCACTGATGGCTCCAACTA CACACTTTTAAAACAGGGATTAAACAATGTTATTGCTATAGACTTTGATTACAGAGAAGAATTCATCTATTGGATCGATTCTAGCCGACC CAATGGCAGTCGCATAAATAGAATGTGTTTAAATGGAAGTGACATTAAGGTAGTTCATAACACAGCGGTCCCCAATGCACTTGCTGTCGA TTGGATTGGAAAAAACCTCTATTGGTCTGACACAGAAAAAAGAATCATTGAAGTATCCAAACTCAATGGCTTGTACCCTACTATACTCGT TAGCAAAAGGCTGAAGTTTCCCAGAGACTTGTCTTTAGATCCTCAAGCTGGATATTTGTATTGGATTGACTGCTGCGAGTATCCTCATAT TGGCCGTGTTGGAATGGATGGAACCAATCAGAGTGTTGTCATAGAAACCAAGATTTCTAGACCTATGGCACTAACAATAGATTATGTTAA TCGTAGACTCTACTGGGCCGATGAAAATCACATTGAATTTAGCAACATGGATGGATCTCATAGACACAAAGTCCCTAATCAAGATATTCC AGGGGTGATTGCACTAACATTGTTTGAAGACTACATCTACTGGACTGATGGGAAAACCAAGTCACTCAGCCGTGCCCATAAAACATCGGG AGCAGACAGACTCTCACTGATTTACTCATGGCATGCCATCACAGATATCCAGGTGTATCATTCTTATAGACAACCTGATGTCTCCAAACA TCTCTGCATGATAAATAATGGTGGTTGCAGTCATTTGTGCCTTTTAGCCCCTGGAAAAACCCACACTTGTGCATGTCCCACTAACTTCTA TCTGGCAGCTGATAATAGGACTTGCTTATCCAACTGCACAGCCAGCCAGTTTCGTTGCAAAACTGACAAATGTATTCCATTCTGGTGGAA ATGTGACACCGTGGATGACTGTGGTGATGGATCTGATGAACCTGATGACTGTCCTGAATTTAGATGTCAGCCAGGCCGATTTCAGTGTGG GACTGGACTCTGTGCTCTACCAGCTTTCATCTGTGATGGAGAGAATGATTGTGGAGACAATTCTGATGAACTCAACTGTGACACACATGT CTGCCTGTCAGGTCAATTCAAATGTACCAAGAACCAGAAATGTATCCCAGTAAACTTAAGATGTAATGGGCAAGATGACTGTGGTGATGA GGAAGATGAAAGAGACTGTCCTGAAAACAGCTGTTCTCCAGACTATTTCCAGTGTAAGACTACGAAGCATTGCATTTCCAAGCTGTGGGT TTGTGACGAGGATCCAGACTGTGCAGATGCATCAGACGAGGCCAACTGCGATAAAAAGACTTGTGGACCTCATGAATTCCAGTGTAAAAA CAACAACTGTATTCCCGATCACTGGCGGTGTGATAGCCAAAATGACTGCAGTGATAATTCAGATGAAGAAAACTGTAAGCCACAGACATG TACATTGAAAGATTTCCTCTGTGCCAATGGGGACTGTGTTTCTTCAAGGTTTTGGTGTGATGGAGATTTTGACTGTGCAGATGGCTCTGA TGAGAGAAATTGTGAGACAAGTTGTTCCAAAGATCAGTTCCGGTGTTCCAATGGTCAGTGTATACCAGCAAAATGGAAATGTGATGGCCA TGAAGACTGCAAATATGGGGAAGATGAGAAAAGCTGTGAGCCAGCTTCTCCTACTTGCTCATCACGTGAATATATATGTGCCAGTGATGG ATGTATTTCAGCATCTTTGAAATGTAATGGAGAATATGATTGTGCTGATGGTTCAGATGAGATGGACTGTGTGACTGAATGTAAGGAAGA TCAGTTTCGGTGCAAAAATAAAGCCCACTGTATTCCAATTAGATGGCTGTGTGATGGAATTCATGACTGTGTGGATGGCAGTGATGAAGA GAACTGTGAAAGAGGAGGAAATATATGTAGAGCTGATGAGTTCCTTTGCAATAATTCTCTCTGCAAACTACATTTCTGGGTGTGTGATGG AGAGGACGACTGTGGAGACAACTCTGATGAAGCCCCTGATATGTGTGTCAAATTTCTTTGTCCATCCACGAGACCTCACAGATGCAGAAA TAACAGAATATGCCTACAGTCGGAGCAAATGTGCAATGGGATTGATGAATGCGGTGACAATTCAGATGAAGATCACTGTGGTGGTAAGCT GACATATAAAGCAAGGCCTTGTAAAAAGGATGAGTTTGCTTGTAGTAATAAAAAATGCATCCCTATGGATCTCCAGTGTGATCGACTTGA TGACTGCGGAGATGGTTCAGATGAGCAAGGATGCAGAATAGCTCCTACTGAATATACCTGTGAAGATAATGTGAATCCATGTGGAGATGA TGCATATTGTAATCAAATAAAAACATCTGTTTTCTGTCGCTGTAAGCCTGGATTTCAGAGAAACATGAAAAACAGACAATGTGAAGACCT TAATGAATGTTTGGTGTTTGGCACATGTTCCCATCAATGTATAAATGTGGAAGGATCATATAAATGTGTGTGTGACCAGAATTTTCAAGA AAGAAATAACACCTGCATAGCAGAAGGCTCTGAAGATCAAGTTCTCTACATTGCTAATGACACTGATATCCTGGGTTTTATATATCCATT CAACTACAGTGGCGATCATCAACAAATTTCTCATATTGAACATAATTCAAGAATAACAGGGATGGATGTATATTATCAAAGAGATATGAT TATTTGGAGTACTCAGTTTAATCCAGGCGGAATTTTCTACAAAAGGATCCATGGCAGAGAAAAAAGGCAAGCAAACAGTGGCTTGATTTG TCCTGAATTTAAAAGGCCCAGGGACATTGCAGTTGACTGGGTGGCTGGAAACATTTACTGGACTGATCATTCTAGAATGCATTGGTTCAG TTACTACACTACTCACTGGACCAGTCTGAGGTACTCTATCAACGTAGGGCAGCTGAATGGCCCCAACTGCACCAGACTCTTAACAAATAT GGCTGGAGAACCCTATGCTATTGCAGTAAATCCTAAAAGAGGGATGATGTACTGGACTGTTGTTGGGGATCATTCCCATATAGAAGAAGC AGCCATGGATGGTACACTGAGAAGGATTTTAGTACAAAAGAACTTACAGAGACCCACAGGTTTGGCTGTGGATTATTTTAGTGAACGCAT ATATTGGGCTGACTTTGAGCTCTCCATCATTGGCAGTGTTCTGTATGATGGCTCTAATTCAGTAGTCTCTGTCAGCAGCAAACAAGGTTT ATTACATCCACATAGGATCGATATCTTTGAAGATTATATATATGGAGCAGGACCTAAAAATGGTGTATTTCGAGTTCAAAAATTTGGCCA TGGTTCAGTAGAGTACTTAGCTTTAAATATTGATAAAACAAAAGGTGTTTTGATATCTCATCGTTATAAACAACTAGATTTACCCAATCC ATGCTTGGATTTAGCATGCGAATTTCTTTGCTTGCTAAATCCTTCTGGGGCCACTTGTGTGTGTCCAGAAGGAAAATATTTGATTAATGG CACCTGCAATGATGACAGCCTGTTAGATGATTCATGTAAGTTAACTTGTGAAAATGGAGGAAGATGCATTTTAAATGAGAAAGGTGATTT GAGGTGTCACTGTTGGCCCAGTTATTCAGGAGAAAGATGTGAAGTCAACCACTGTAGCAACTACTGCCAGAATGGAGGAACTTGCGTACC ATCAGTTCTAGGGAGACCCACCTGCAGCTGTGCACTGGGTTTCACTGGGCCAAACTGTGGTAAGACAGTCTGTGAGGATTTTTGTCAAAA TGGAGGAACCTGCATTGTGACTGCTGGAAACCAGCCTTACTGCCACTGCCAGCCGGAATACACCGGAGACAGATGTCAGTACTACGTGTG CCACCACTATTGTGTGAATTCTGAATCATGTACCATTGGGGATGATGGAAGTGTTGAATGTGTCTGTCCAACGCGCTATGAAGGACCAAA ATGTGAGGTTGACAAGTGTGTAAGGTGCCATGGGGGGCACTGCATTATAAATAAAGACAGTGAAGATATATTTTGCAACTGCACTAATGG AAAGATTGCCTCTAGCTGTCAGTTATGTGATGGCTACTGTTACAATGGTGGCACATGCCAGCTGGACCCCGAGACAAATGTACCTGTGTG TCTATGCTCCACCAACTGGTCAGGCACACAGTGTGAAAGGCCAGCCCCAAAGAGCAGCAAGTCTGATCATATCAGCACAAGAAGCATTGC CATCATTGTGCCTCTCGTCCTCTTGGTGACTTTGATAACCACCTTAGTAATTGGTTTAGTGCTTTGTAAAAGAAAAAGAAGGACAAAAAC AATTAGAAGACAACCTATTATCAATGGAGGAATAAATGTAGAAATTGGCAATCCATCTTATAACATGTATGAGGTAGATCATGATCACAA CGATGGAGGTCTTTTAGATCCTGGCTTTATGATAGACCCAACAAAGGCCAGGTACATAGGGGGAGGACCCAGTGCTTTCAAGCTTCCACA CACAGCGCCGCCCATCTACCTAAACTCTGATTTGAAAGGACCACTAACTGCTGGGCCAACAAATTACTCCAATCCGGTATATGCAAAATT ATATATGGATGGGCAAAACTGTCGAAACTCCTTAGGAAGTGTTGATGAAAGGAAAGAACTGCTTCCAAAGAAAATAGAAATTGGTATAAG AGAGACAGTGGCATAATCAGTGATATCTTTTATATGCTGTATAAATGTATAAAATATAAGGATTACTTTTGTATGTTCCAACAGTATTAT ACTTGTTTTGGCATCAGCATTACCTCTTTCTTTATCTTTTTCCTGGTTAATTGTTTTCTGAGTTTTTTGGGTTTTATTTTTTGCTGATGA CTATTGATTGACCATTTGTATGGTATTTTTATGAAAAAGAACTGCACTACAGTACAATTTACAACAATGCTGCTGATATGACACACCTTT GAATTTGTTAAAATTAAAAACAACGTATTCCTTTGTAGTGTGAATATGAGCAATCTATTTTATATGAACTTTTTTGGTTGTACTTAATCA ACGAGGAGAATCTCTGCACTTTTCCATTATACGGTTTGAAGGCTGTAATACAGTGTCATATTATTTTTCTGTTTAAATTGATGGAAAAAT GATTGAATGGTCAACTCTCTTCTTTGTGCCCATAAAGATCGATTCAGACTCTGCTGAAAATATATAGCTCTCACAAGTTCAGCATCACCT GCTTTGAAATTAGCCTTAGATTGCCAACCAATAGATGAGAATTTTGAGGAAAAAAATTAAAAATATGTAAAATTAATAATTTGCATGAAC ACAGATGACTACATTTTCCAAAACTTAGTGGACTCTATGTGATGTACTAAATGTATACACCTTGTAAGCAATAGTTATATTTAGGTGGTA GAACATAGCAAAAATATAACCGAAAGTTGGCCGACTGCACTTGCTATGGAATAAGACCTTTTATTCTCCCTCAGTCTCGAGATAAATAGC CAGCCTAGAGCACAACAGGGCATTGGGTACTTGCATCTTAGGTATTTCTTCCCAGTCACATCCATTTTGTGGAAGATTAACCCAACCCCT TACACTACACTGAACACTAAAGAATAATATATAAGCACACAAATTGGTGACAGAATTTCAATTACGTGAACGCATCCTCTTTGCTAGGTC AAAAAACAAAGGGCAAAGCAGACATTTTAGTATACAGAGTGATTGGCAAATATTTTCAAGATTTAATATGAGCAACCCATTATTTGCCCT ATCCAAAATATATTCAAGGGCCTTCCAAGTTGTAGAAGAACAATGATCTTCCCATAATCAAAAGTGGAGAGTCGAAATGCTGTGCCAGTT GCTCTGGTATTCAGGTTTCTCTGGGTTTTACAGAACGCATGGACCCCATTCACGTTTGGTTTGTTTATCTTCAAATTTGAGTTGAAACGA GTGCGATTTATTTAAGTTGTATATAAAAATAAAAGGATAGCATTTTTATACAAATATCTTTAAAGGCACAAAAGATTTATTCACAAGTTT TGGAGGGCTTTTTGTTCCTCTGATAGACATGACTGACTTTTAGCTGTCATAATGTATTAACCTAACAGATGAAATATGTTAAATATGTGG TTGCTCTTTATCCCTTTGTACAAGCATTAAAAAAACTGCTGTTTTATAAGAAGACTTTTTGTTGTACTATGTGCATGCATACTACCTATT TCTAAACTTTGCCATATTGAGGCCTTTATAAACTATTGATTTATGTAATACTAGTGCAATTTTGCTTGAACAATGTTATGCATATCATAA ACTTTTTCAGGTTCTTGTTTAAGTACATTTTTTAAATTGAACAGTATTTTTCATTTTGGTTATAATATAGTCATTTTGCCTATGTTTCTA >In-frame_ENST00000446250_ENST00000389484_TCGA-AJ-A3NF-01A_VPS53_chr17_463666_-_LRP1B_chr2_142012210_length(amino acids)=4492AA_start in transcript=1927_stop in transcript=15405 MSGHHPAELLSNCQQLNCQYKCTMVRNSTRCYCEDGFEITEDGRSCKDQDECAVYGTCSQTCRNTHGSYTCSCVEGYLMQPDNRSCKAKI EPTDRPPILLIANFETIEVFYLNGSKMATLSSVNGNEIHTLDFIYNEDMICWIESRESSNQLKCIQITKAGGLTDEWTINILQSFHNVQQ MAIDWLTRNLYFVDHVGDRIFVCNSNGSVCVTLIDLELHNPKAIAVDPIAGKLFFTDYGNVAKVERCDMDGMNRTRIIDSKTEQPAALAL DLVNKLVYWVDLYLDYVGVVDYQGKNRHTVIQGRQVRHLYGITVFEDYLYATNSDNYNIVRINRFNGTDIHSLIKIENAWGIRIYQKRTQ PTVRSHACEVDPYGMPGGCSHICLLSSSYKTRTCRCRTGFNLGSDGRSCKRPKNELFLFYGKGRPGIVRGMDLNTKIADEYMIPIENLVN PRALDFHAETNYIYFADTTSFLIGRQKIDGTERETILKDDLDNVEGIAVDWIGNNLYWTNDGHRKTINVARLEKASQSRKTLLEGEMSHP RGIVVDPVNGWMYWTDWEEDEIDDSVGRIEKAWMDGFNRQIFVTSKMLWPNGLTLDFHTNTLYWCDAYYDHIEKVFLNGTHRKIVYSGRE LNHPFGLSHHGNYVFWTDYMNGSIFQLDLITSEVTLLRHERPPLFGLQIYDPRKQQGDNMCRVNNGGCSTLCLAIPGGRVCACADNQLLD ENGTTCTFNPGEALPHICKAGEFRCKNRHCIQARWKCDGDDDCLDGSDEDSVNCFNHSCPDDQFKCQNNRCIPKRWLCDGANDCGSNEDE SNQTCTARTCQVDQFSCGNGRCIPRAWLCDREDDCGDQTDEMASCEFPTCEPLTQFVCKSGRCISSKWHCDSDDDCGDGSDEVGCVHSCF DNQFRCSSGRCIPGHWACDGDNDCGDFSDEAQINCTKEEIHSPAGCNGNEFQCHPDGNCVPDLWRCDGEKDCEDGSDEKGCNGTIRLCDH KTKFSCWSTGRCINKAWVCDGDIDCEDQSDEDDCDSFLCGPPKHPCANDTSVCLQPEKLCNGKKDCPDGSDEGYLCDECSLNNGGCSNHC SVVPGRGIVCSCPEGLQLNKDNKTCEIVDYCSNHLKCSQVCEQHKHTVKCSCYEGWKLDVDGESCTSVDPFEAFIIFSIRHEIRRIDLHK RDYSLLVPGLRNTIALDFHFNQSLLYWTDVVEDRIYRGKLSESGGVSAIEVVVEHGLATPEGLTVDWIAGNIYWIDSNLDQIEVAKLDGS LRTTLIAGAMEHPRAIALDPRYGILFWTDWDANFPRIESASMSGAGRKTIYKDMKTGAWPNGLTVDHFEKRIVWTDARSDAIYSALYDGT NMIEIIRGHEYLSHPFAVSLYGSEVYWTDWRTNTLSKANKWTGQNVSVIQKTSAQPFDLQIYHPSRQPQAPNPCAANDGKGPCSHMCLIN HNRSAACACPHLMKLSSDKKTCYEMKKFLLYARRSEIRGVDIDNPYFNFITAFTVPDIDDVTVIDFDASEERLYWTDIKTQTIKRAFING TGLETVISRDIQSIRGLAVDWVSRNLYWISSEFDETQINVARLDGSLKTSIIHGIDKPQCLAAHPVRGKLYWTDGNTINMANMDGSNSKI LFQNQKEPVGLSIDYVENKLYWISSGNGTINRCNLDGGNLEVIESMKEELTKATALTIMDKKLWWADQNLAQLGTCSKRDGRNPTILRNK TSGVVHMKVYDKEAQQGSNSCQLNNGGCSQLCLPTSETTRTCMCTVGYYLQKNRMSCQGIESFLMYSVHEGIRGIPLEPSDKMDALMPIS GTSFAVGIDFHAENDTIYWTDMGFNKISRAKRDQTWKEDIITNGLGRVEGIAVDWIAGNIYWTDHGFNLIEVARLNGSFRYVIISQGLDQ PRSIAVHPEKGLLFWTEWGQMPCIGKARLDGSEKVVLVSMGIAWPNGISIDYEENKLYWCDARTDKIERIDLETGGNREMVLSGSNVDMF SVAVFGAYIYWSDRAHANGSVRRGHKNDATETITMRTGLGVNLKEVKIFNRVREKGTNVCARDNGGCKQLCLYRGNSRRTCACAHGYLAE DGVTCLRHEGYLLYSGRTILKSIHLSDETNLNSPIRPYENPRYFKNVIALAFDYNQRRKGTNRIFYSDAHFGNIQLIKDNWEDRQVIVEN VGSVEGLAYHRAWDTLYWTSSTTSSITRHTVDQTRPGAFDREAVITMSEDDHPHVLALDECQNLMFWTNWNEQHPSIMRSTLTGKNAQVV VSTDILTPNGLTIDYRAEKLYFSDGSLGKIERCEYDGSQRHVIVKSGPGTFLSLAVYDNYIFWSDWGRRAILRSNKYTGGDTKILRSDIP HQPMGIIAVANDTNSCELSPCALLNGGCHDLCLLTPNGRVNCSCRGDRILLEDNRCVTKNSSCNAYSEFECGNGECIDYQLTCDGIPHCK DKSDEKLLYCENRSCRRGFKPCYNRRCIPHGKLCDGENDCGDNSDELDCKVSTCATVEFRCADGTCIPRSARCNQNIDCADASDEKNCNN TDCTHFYKLGVKTTGFIRCNSTSLCVLPTWICDGSNDCGDYSDELKCPVQNKHKCEENYFSCPSGRCILNTWICDGQKDCEDGRDEFHCD SSCSWNQFACSAQKCISKHWICDGEDDCGDGLDESDSICGAITCAADMFSCQGSRACVPRHWLCDGERDCPDGSDELSTAGCAPNNTCDE NAFMCHNKVCIPKQFVCDHDDDCGDGSDESPQCGYRQCGTEEFSCADGRCLLNTQWQCDGDFDCPDHSDEAPLNPKCKSAEQSCNSSFFM CKNGRCIPSGGLCDNKDDCGDGSDERNCHINECLSKKVSGCSQDCQDLPVSYKCKCWPGFQLKDDGKTCVDIDECSSGFPCSQQCINTYG TYKCLCTDGYEIQPDNPNGCKSLSDEEPFLILADHHEIRKISTDGSNYTLLKQGLNNVIAIDFDYREEFIYWIDSSRPNGSRINRMCLNG SDIKVVHNTAVPNALAVDWIGKNLYWSDTEKRIIEVSKLNGLYPTILVSKRLKFPRDLSLDPQAGYLYWIDCCEYPHIGRVGMDGTNQSV VIETKISRPMALTIDYVNRRLYWADENHIEFSNMDGSHRHKVPNQDIPGVIALTLFEDYIYWTDGKTKSLSRAHKTSGADRLSLIYSWHA ITDIQVYHSYRQPDVSKHLCMINNGGCSHLCLLAPGKTHTCACPTNFYLAADNRTCLSNCTASQFRCKTDKCIPFWWKCDTVDDCGDGSD EPDDCPEFRCQPGRFQCGTGLCALPAFICDGENDCGDNSDELNCDTHVCLSGQFKCTKNQKCIPVNLRCNGQDDCGDEEDERDCPENSCS PDYFQCKTTKHCISKLWVCDEDPDCADASDEANCDKKTCGPHEFQCKNNNCIPDHWRCDSQNDCSDNSDEENCKPQTCTLKDFLCANGDC VSSRFWCDGDFDCADGSDERNCETSCSKDQFRCSNGQCIPAKWKCDGHEDCKYGEDEKSCEPASPTCSSREYICASDGCISASLKCNGEY DCADGSDEMDCVTECKEDQFRCKNKAHCIPIRWLCDGIHDCVDGSDEENCERGGNICRADEFLCNNSLCKLHFWVCDGEDDCGDNSDEAP DMCVKFLCPSTRPHRCRNNRICLQSEQMCNGIDECGDNSDEDHCGGKLTYKARPCKKDEFACSNKKCIPMDLQCDRLDDCGDGSDEQGCR IAPTEYTCEDNVNPCGDDAYCNQIKTSVFCRCKPGFQRNMKNRQCEDLNECLVFGTCSHQCINVEGSYKCVCDQNFQERNNTCIAEGSED QVLYIANDTDILGFIYPFNYSGDHQQISHIEHNSRITGMDVYYQRDMIIWSTQFNPGGIFYKRIHGREKRQANSGLICPEFKRPRDIAVD WVAGNIYWTDHSRMHWFSYYTTHWTSLRYSINVGQLNGPNCTRLLTNMAGEPYAIAVNPKRGMMYWTVVGDHSHIEEAAMDGTLRRILVQ KNLQRPTGLAVDYFSERIYWADFELSIIGSVLYDGSNSVVSVSSKQGLLHPHRIDIFEDYIYGAGPKNGVFRVQKFGHGSVEYLALNIDK TKGVLISHRYKQLDLPNPCLDLACEFLCLLNPSGATCVCPEGKYLINGTCNDDSLLDDSCKLTCENGGRCILNEKGDLRCHCWPSYSGER CEVNHCSNYCQNGGTCVPSVLGRPTCSCALGFTGPNCGKTVCEDFCQNGGTCIVTAGNQPYCHCQPEYTGDRCQYYVCHHYCVNSESCTI GDDGSVECVCPTRYEGPKCEVDKCVRCHGGHCIINKDSEDIFCNCTNGKIASSCQLCDGYCYNGGTCQLDPETNVPVCLCSTNWSGTQCE RPAPKSSKSDHISTRSIAIIVPLVLLVTLITTLVIGLVLCKRKRRTKTIRRQPIINGGINVEIGNPSYNMYEVDHDHNDGGLLDPGFMID -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for VPS53-LRP1B |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for VPS53-LRP1B |
![]() (DrugBank Version 5.1.8 2021-05-08) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for VPS53-LRP1B |
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Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Hgene | VPS53 | C4014488 | PONTOCEREBELLAR HYPOPLASIA, TYPE 2E | 3 | CTD_human;GENOMICS_ENGLAND;UNIPROT |
Hgene | VPS53 | C0266468 | Congenital pontocerebellar hypoplasia | 1 | GENOMICS_ENGLAND |
Hgene | VPS53 | C0424605 | Developmental delay (disorder) | 1 | GENOMICS_ENGLAND |
Hgene | VPS53 | C0557874 | Global developmental delay | 1 | GENOMICS_ENGLAND |
Hgene | VPS53 | C3714756 | Intellectual Disability | 1 | GENOMICS_ENGLAND |
Tgene | LRP1B | C0007134 | Renal Cell Carcinoma | 1 | CTD_human |
Tgene | LRP1B | C0025202 | melanoma | 1 | CTD_human |
Tgene | LRP1B | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
Tgene | LRP1B | C0279702 | Conventional (Clear Cell) Renal Cell Carcinoma | 1 | CTD_human |
Tgene | LRP1B | C0376358 | Malignant neoplasm of prostate | 1 | CTD_human |
Tgene | LRP1B | C1266042 | Chromophobe Renal Cell Carcinoma | 1 | CTD_human |
Tgene | LRP1B | C1266043 | Sarcomatoid Renal Cell Carcinoma | 1 | CTD_human |
Tgene | LRP1B | C1266044 | Collecting Duct Carcinoma of the Kidney | 1 | CTD_human |
Tgene | LRP1B | C1306837 | Papillary Renal Cell Carcinoma | 1 | CTD_human |