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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ZBTB17-MTOR (FusionGDB2 ID:99653)

Fusion Gene Summary for ZBTB17-MTOR

check button Fusion gene summary
Fusion gene informationFusion gene name: ZBTB17-MTOR
Fusion gene ID: 99653
HgeneTgene
Gene symbol

ZBTB17

MTOR

Gene ID

7709

2475

Gene namezinc finger and BTB domain containing 17mechanistic target of rapamycin kinase
SynonymsMIZ-1|ZNF151|ZNF60|pHZ-67FRAP|FRAP1|FRAP2|RAFT1|RAPT1|SKS
Cytomap

1p36.13

1p36.22

Type of geneprotein-codingprotein-coding
Descriptionzinc finger and BTB domain-containing protein 17Myc-interacting Zn finger protein-1zinc finger protein 151 (pHZ-67)zinc finger protein 60serine/threonine-protein kinase mTORFK506 binding protein 12-rapamycin associated protein 2FK506-binding protein 12-rapamycin complex-associated protein 1FKBP-rapamycin associated proteinFKBP12-rapamycin complex-associated protein 1mammalian target o
Modification date2020031320200329
UniProtAcc.

TLDC1

Ensembl transtripts involved in fusion geneENST00000375743, ENST00000537142, 
ENST00000375733, ENST00000448462, 
ENST00000479282, 		ENST00000361445, 
ENST00000376838, ENST00000495435, 
Fusion gene scores* DoF score8 X 7 X 6=33612 X 11 X 8=1056
# samples 919
** MAII scorelog2(9/336*10)=-1.90046432644909
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(19/1056*10)=-2.47453851102751
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ZBTB17 [Title/Abstract] AND MTOR [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointZBTB17(16269559)-MTOR(11227574), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneZBTB17

GO:0008285

negative regulation of cell proliferation

19160485

HgeneZBTB17

GO:0045944

positive regulation of transcription by RNA polymerase II

9312026

HgeneZBTB17

GO:0071158

positive regulation of cell cycle arrest

19160485

TgeneMTOR

GO:0001558

regulation of cell growth

18762023

TgeneMTOR

GO:0001934

positive regulation of protein phosphorylation

20233713

TgeneMTOR

GO:0006468

protein phosphorylation

12150926|15467718|18925875

TgeneMTOR

GO:0009267

cellular response to starvation

28223137

TgeneMTOR

GO:0010507

negative regulation of autophagy

30704899

TgeneMTOR

GO:0016242

negative regulation of macroautophagy

25327288

TgeneMTOR

GO:0016310

phosphorylation

11853878|25327288

TgeneMTOR

GO:0031667

response to nutrient levels

29750193

TgeneMTOR

GO:0034198

cellular response to amino acid starvation

22424946

TgeneMTOR

GO:0038202

TORC1 signaling

28223137

TgeneMTOR

GO:0043200

response to amino acid

18497260

TgeneMTOR

GO:0045727

positive regulation of translation

18762023

TgeneMTOR

GO:0046777

protein autophosphorylation

15467718

TgeneMTOR

GO:0071230

cellular response to amino acid stimulus

22424946

TgeneMTOR

GO:0071233

cellular response to leucine

22424946

TgeneMTOR

GO:1990253

cellular response to leucine starvation

22424946


check buttonFusion gene breakpoints across ZBTB17 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across MTOR (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-4357-01AZBTB17chr1

16269559

-MTORchr1

11227574

-


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Fusion Gene ORF analysis for ZBTB17-MTOR

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000375743ENST00000361445ZBTB17chr1

16269559

-MTORchr1

11227574

-
5CDS-intronENST00000375743ENST00000376838ZBTB17chr1

16269559

-MTORchr1

11227574

-
5CDS-intronENST00000375743ENST00000495435ZBTB17chr1

16269559

-MTORchr1

11227574

-
In-frameENST00000537142ENST00000361445ZBTB17chr1

16269559

-MTORchr1

11227574

-
5CDS-intronENST00000537142ENST00000376838ZBTB17chr1

16269559

-MTORchr1

11227574

-
5CDS-intronENST00000537142ENST00000495435ZBTB17chr1

16269559

-MTORchr1

11227574

-
In-frameENST00000375733ENST00000361445ZBTB17chr1

16269559

-MTORchr1

11227574

-
5CDS-intronENST00000375733ENST00000376838ZBTB17chr1

16269559

-MTORchr1

11227574

-
5CDS-intronENST00000375733ENST00000495435ZBTB17chr1

16269559

-MTORchr1

11227574

-
intron-3CDSENST00000448462ENST00000361445ZBTB17chr1

16269559

-MTORchr1

11227574

-
intron-intronENST00000448462ENST00000376838ZBTB17chr1

16269559

-MTORchr1

11227574

-
intron-intronENST00000448462ENST00000495435ZBTB17chr1

16269559

-MTORchr1

11227574

-
intron-3CDSENST00000479282ENST00000361445ZBTB17chr1

16269559

-MTORchr1

11227574

-
intron-intronENST00000479282ENST00000376838ZBTB17chr1

16269559

-MTORchr1

11227574

-
intron-intronENST00000479282ENST00000495435ZBTB17chr1

16269559

-MTORchr1

11227574

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000375743ZBTB17chr116269559-ENST00000361445MTORchr111227574-64082061190954571182
ENST00000537142ZBTB17chr116269559-ENST00000361445MTORchr111227574-61761829167752251182
ENST00000375733ZBTB17chr116269559-ENST00000361445MTORchr111227574-64142067191554631182

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000375743ENST00000361445ZBTB17chr116269559-MTORchr111227574-0.0214171130.97858286
ENST00000537142ENST00000361445ZBTB17chr116269559-MTORchr111227574-0.0189182310.9810817
ENST00000375733ENST00000361445ZBTB17chr116269559-MTORchr111227574-0.0213819650.978618

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Fusion Genomic Features for ZBTB17-MTOR


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ZBTB17-MTOR


check button Go to

FGviewer for the breakpoints of chr1:16269559-chr1:11227574

.
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.MTOR

TLDC1

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.456

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375733-13161_104609.3333333333334811.0DomainBTB
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375743-13161_104609.3333333333334804.0DomainBTB
HgeneZBTB17chr1:16269559chr1:11227574ENST00000537142-12151_104527.3333333333334722.0DomainBTB
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375733-1316306_328609.3333333333334811.0Zinc fingerC2H2-type 1
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375733-1316334_356609.3333333333334811.0Zinc fingerC2H2-type 2
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375733-1316362_384609.3333333333334811.0Zinc fingerC2H2-type 3
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375733-1316390_412609.3333333333334811.0Zinc fingerC2H2-type 4
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375733-1316418_440609.3333333333334811.0Zinc fingerC2H2-type 5
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375733-1316446_468609.3333333333334811.0Zinc fingerC2H2-type 6
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375733-1316474_496609.3333333333334811.0Zinc fingerC2H2-type 7
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375733-1316502_524609.3333333333334811.0Zinc fingerC2H2-type 8
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375733-1316530_552609.3333333333334811.0Zinc fingerC2H2-type 9
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375733-1316558_580609.3333333333334811.0Zinc fingerC2H2-type 10
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375733-1316586_608609.3333333333334811.0Zinc fingerC2H2-type 11
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375743-1316306_328609.3333333333334804.0Zinc fingerC2H2-type 1
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375743-1316334_356609.3333333333334804.0Zinc fingerC2H2-type 2
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375743-1316362_384609.3333333333334804.0Zinc fingerC2H2-type 3
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375743-1316390_412609.3333333333334804.0Zinc fingerC2H2-type 4
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375743-1316418_440609.3333333333334804.0Zinc fingerC2H2-type 5
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375743-1316446_468609.3333333333334804.0Zinc fingerC2H2-type 6
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375743-1316474_496609.3333333333334804.0Zinc fingerC2H2-type 7
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375743-1316502_524609.3333333333334804.0Zinc fingerC2H2-type 8
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375743-1316530_552609.3333333333334804.0Zinc fingerC2H2-type 9
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375743-1316558_580609.3333333333334804.0Zinc fingerC2H2-type 10
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375743-1316586_608609.3333333333334804.0Zinc fingerC2H2-type 11
HgeneZBTB17chr1:16269559chr1:11227574ENST00000537142-1215306_328527.3333333333334722.0Zinc fingerC2H2-type 1
HgeneZBTB17chr1:16269559chr1:11227574ENST00000537142-1215334_356527.3333333333334722.0Zinc fingerC2H2-type 2
HgeneZBTB17chr1:16269559chr1:11227574ENST00000537142-1215362_384527.3333333333334722.0Zinc fingerC2H2-type 3
HgeneZBTB17chr1:16269559chr1:11227574ENST00000537142-1215390_412527.3333333333334722.0Zinc fingerC2H2-type 4
HgeneZBTB17chr1:16269559chr1:11227574ENST00000537142-1215418_440527.3333333333334722.0Zinc fingerC2H2-type 5
HgeneZBTB17chr1:16269559chr1:11227574ENST00000537142-1215446_468527.3333333333334722.0Zinc fingerC2H2-type 6
HgeneZBTB17chr1:16269559chr1:11227574ENST00000537142-1215474_496527.3333333333334722.0Zinc fingerC2H2-type 7
HgeneZBTB17chr1:16269559chr1:11227574ENST00000537142-1215502_524527.3333333333334722.0Zinc fingerC2H2-type 8
TgeneMTORchr1:16269559chr1:11227574ENST0000036144527582182_25161417.66666666666672550.0DomainPI3K/PI4K
TgeneMTORchr1:16269559chr1:11227574ENST0000036144527582517_25491417.66666666666672550.0DomainFATC
TgeneMTORchr1:16269559chr1:11227574ENST0000036144527581443_14731417.66666666666672550.0RepeatNote=TPR 4
TgeneMTORchr1:16269559chr1:11227574ENST0000036144527581474_15071417.66666666666672550.0RepeatNote=TPR 5
TgeneMTORchr1:16269559chr1:11227574ENST0000036144527581508_15411417.66666666666672550.0RepeatNote=TPR 6
TgeneMTORchr1:16269559chr1:11227574ENST0000036144527581542_15741417.66666666666672550.0RepeatNote=TPR 7
TgeneMTORchr1:16269559chr1:11227574ENST0000036144527581575_16141417.66666666666672550.0RepeatNote=TPR 8
TgeneMTORchr1:16269559chr1:11227574ENST0000036144527581615_16491417.66666666666672550.0RepeatNote=TPR 9
TgeneMTORchr1:16269559chr1:11227574ENST0000036144527581650_16931417.66666666666672550.0RepeatNote=TPR 10
TgeneMTORchr1:16269559chr1:11227574ENST0000036144527581694_17311417.66666666666672550.0RepeatNote=TPR 11
TgeneMTORchr1:16269559chr1:11227574ENST0000036144527581732_17861417.66666666666672550.0RepeatNote=TPR 12
TgeneMTORchr1:16269559chr1:11227574ENST0000036144527581787_18461417.66666666666672550.0RepeatNote=TPR 13
TgeneMTORchr1:16269559chr1:11227574ENST0000036144527581898_19301417.66666666666672550.0RepeatNote=TPR 14
TgeneMTORchr1:16269559chr1:11227574ENST0000036144527581931_19701417.66666666666672550.0RepeatNote=TPR 15
TgeneMTORchr1:16269559chr1:11227574ENST0000036144527581971_20051417.66666666666672550.0RepeatNote=TPR 16

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375733-1316614_637609.3333333333334811.0Zinc fingerC2H2-type 12
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375733-1316717_739609.3333333333334811.0Zinc fingerC2H2-type 13
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375743-1316614_637609.3333333333334804.0Zinc fingerC2H2-type 12
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375743-1316717_739609.3333333333334804.0Zinc fingerC2H2-type 13
HgeneZBTB17chr1:16269559chr1:11227574ENST00000537142-1215530_552527.3333333333334722.0Zinc fingerC2H2-type 9
HgeneZBTB17chr1:16269559chr1:11227574ENST00000537142-1215558_580527.3333333333334722.0Zinc fingerC2H2-type 10
HgeneZBTB17chr1:16269559chr1:11227574ENST00000537142-1215586_608527.3333333333334722.0Zinc fingerC2H2-type 11
HgeneZBTB17chr1:16269559chr1:11227574ENST00000537142-1215614_637527.3333333333334722.0Zinc fingerC2H2-type 12
HgeneZBTB17chr1:16269559chr1:11227574ENST00000537142-1215717_739527.3333333333334722.0Zinc fingerC2H2-type 13
TgeneMTORchr1:16269559chr1:11227574ENST0000036144527581382_19821417.66666666666672550.0DomainFAT
TgeneMTORchr1:16269559chr1:11227574ENST000003614452758100_1371417.66666666666672550.0RepeatNote=HEAT 3
TgeneMTORchr1:16269559chr1:11227574ENST0000036144527581029_10681417.66666666666672550.0RepeatNote=HEAT 25
TgeneMTORchr1:16269559chr1:11227574ENST0000036144527581069_11051417.66666666666672550.0RepeatNote=HEAT 26
TgeneMTORchr1:16269559chr1:11227574ENST0000036144527581106_11441417.66666666666672550.0RepeatNote=HEAT 27
TgeneMTORchr1:16269559chr1:11227574ENST0000036144527581145_11881417.66666666666672550.0RepeatNote=HEAT 28
TgeneMTORchr1:16269559chr1:11227574ENST0000036144527581189_12251417.66666666666672550.0RepeatNote=HEAT 29
TgeneMTORchr1:16269559chr1:11227574ENST0000036144527581226_12731417.66666666666672550.0RepeatNote=HEAT 30
TgeneMTORchr1:16269559chr1:11227574ENST0000036144527581274_13111417.66666666666672550.0RepeatNote=HEAT 31
TgeneMTORchr1:16269559chr1:11227574ENST0000036144527581312_13451417.66666666666672550.0RepeatNote=HEAT 32
TgeneMTORchr1:16269559chr1:11227574ENST0000036144527581346_13821417.66666666666672550.0RepeatNote=TPR 1
TgeneMTORchr1:16269559chr1:11227574ENST0000036144527581383_14081417.66666666666672550.0RepeatNote=TPR 2
TgeneMTORchr1:16269559chr1:11227574ENST000003614452758138_1791417.66666666666672550.0RepeatNote=HEAT 4
TgeneMTORchr1:16269559chr1:11227574ENST0000036144527581409_14421417.66666666666672550.0RepeatNote=TPR 3
TgeneMTORchr1:16269559chr1:11227574ENST00000361445275816_531417.66666666666672550.0RepeatNote=HEAT 1
TgeneMTORchr1:16269559chr1:11227574ENST000003614452758180_2201417.66666666666672550.0RepeatNote=HEAT 5
TgeneMTORchr1:16269559chr1:11227574ENST000003614452758222_2761417.66666666666672550.0RepeatNote=HEAT 6
TgeneMTORchr1:16269559chr1:11227574ENST000003614452758277_3131417.66666666666672550.0RepeatNote=HEAT 7
TgeneMTORchr1:16269559chr1:11227574ENST000003614452758314_3641417.66666666666672550.0RepeatNote=HEAT 8
TgeneMTORchr1:16269559chr1:11227574ENST000003614452758365_4091417.66666666666672550.0RepeatNote=HEAT 9
TgeneMTORchr1:16269559chr1:11227574ENST000003614452758410_4451417.66666666666672550.0RepeatNote=HEAT 10
TgeneMTORchr1:16269559chr1:11227574ENST000003614452758446_4941417.66666666666672550.0RepeatNote=HEAT 11
TgeneMTORchr1:16269559chr1:11227574ENST000003614452758495_5291417.66666666666672550.0RepeatNote=HEAT 12
TgeneMTORchr1:16269559chr1:11227574ENST000003614452758530_5631417.66666666666672550.0RepeatNote=HEAT 13
TgeneMTORchr1:16269559chr1:11227574ENST00000361445275855_991417.66666666666672550.0RepeatNote=HEAT 2
TgeneMTORchr1:16269559chr1:11227574ENST000003614452758564_5961417.66666666666672550.0RepeatNote=HEAT 14
TgeneMTORchr1:16269559chr1:11227574ENST000003614452758597_6361417.66666666666672550.0RepeatNote=HEAT 15
TgeneMTORchr1:16269559chr1:11227574ENST000003614452758637_6831417.66666666666672550.0RepeatNote=HEAT 16
TgeneMTORchr1:16269559chr1:11227574ENST000003614452758686_7241417.66666666666672550.0RepeatNote=HEAT 17
TgeneMTORchr1:16269559chr1:11227574ENST000003614452758727_7661417.66666666666672550.0RepeatNote=HEAT 18
TgeneMTORchr1:16269559chr1:11227574ENST000003614452758769_8111417.66666666666672550.0RepeatNote=HEAT 19
TgeneMTORchr1:16269559chr1:11227574ENST000003614452758814_8531417.66666666666672550.0RepeatNote=HEAT 20
TgeneMTORchr1:16269559chr1:11227574ENST000003614452758857_8931417.66666666666672550.0RepeatNote=HEAT 21
TgeneMTORchr1:16269559chr1:11227574ENST000003614452758894_9421417.66666666666672550.0RepeatNote=HEAT 22
TgeneMTORchr1:16269559chr1:11227574ENST000003614452758943_9881417.66666666666672550.0RepeatNote=HEAT 23
TgeneMTORchr1:16269559chr1:11227574ENST000003614452758989_10271417.66666666666672550.0RepeatNote=HEAT 24


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Fusion Gene Sequence for ZBTB17-MTOR


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>In-frame_ENST00000375743_ENST00000361445_TCGA-BR-4357-01A_ZBTB17_chr1_16269559_-_MTOR_chr1_11227574_length(transcript)=6408nt_BP=2061nt
CGGAAGTTGCAGCCGGGAAGCCTGCGAGGTCGGTTCCGCCCGACTCTAACATGGCGGCGCCCTTTGTCTGCTCTGGAGTGCCGTCCCCGG
CCTTCTCGCGGCCGTGATGCACCTCCCTCTGCGGTGGGGTCCGGGACATGGCAGGTAATGAGCCGGACGAGGGGAGCCAAGCTGGAGTTT
ACACAGGCAAACTGTCAGAAAAGAGTAGCCTGGGCTGTCTGGAAATCTGAGCCATGGACTTTCCCCAGCACAGCCAGCATGTCTTGGAAC
AGCTGAACCAGCAGCGGCAGCTGGGGCTTCTCTGTGACTGCACCTTTGTGGTGGACGGTGTTCACTTTAAGGCTCATAAAGCAGTGCTGG
CGGCCTGCAGCGAGTACTTCAAGATGCTCTTCGTGGACCAGAAGGACGTGGTGCACCTGGACATCAGTAACGCGGCAGGCCTGGGGCAGG
TGCTGGAGTTTATGTACACGGCCAAGCTGAGCCTGAGCCCTGAGAACGTGGATGATGTGCTGGCCGTGGCCACTTTCCTCCAAATGCAGG
ACATCATCACGGCCTGCCATGCCCTCAAGTCACTTGCTGAGCCGGCTACCAGCCCTGGGGGAAATGCGGAGGCCTTGGCCACAGAAGGAG
GGGACAAGAGAGCCAAAGAGGAGAAGGTGGCCACCAGCACGCTGAGCAGGCTGGAGCAGGCAGGACGCAGCACACCCATAGGCCCCAGCA
GGGACCTCAAGGAGGAGCGCGGCGGTCAGGCCCAGAGTGCGGCCAGCGGTGCAGAGCAGACAGAGAAAGCCGATGCGCCCCGGGAGCCGC
CGCCTGTGGAGCTCAAGCCAGACCCCACGAGTGGCATGGCTGCTGCAGAAGCTGAGGCCGCTTTGTCCGAGAGCTCGGAGCAAGAAATGG
AGGTGGAGCCCGCCCGGAAAGGGGAAGAGGAGCAAAAGGAGCAAGAGGAGCAAGAGGAGGAGGGCGCAGGGCCAGCTGAGGTCAAGGAGG
AGGGTTCCCAGCTGGAGAACGGAGAGGCCCCCGAGGAGAACGAGAATGAGGAGTCAGCGGGCACAGACTCGGGGCAGGAGCTCGGCTCCG
AGGCCCGGGGCCTGCGCTCAGGCACCTACGGCGACCGCACGGAGTCCAAGGCCTACGGCTCCGTCATCCACAAGTGCGAGGACTGTGGGA
AGGAGTTCACGCACACGGGGAACTTCAAGCGGCACATCCGCATCCACACGGGGGAGAAGCCCTTCTCGTGCCGGGAGTGCAGCAAGGCCT
TTTCCGACCCGGCCGCGTGCAAGGCCCATGAGAAGACGCACAGCCCTCTGAAGCCCTACGGCTGCGAGGAGTGCGGGAAGAGCTACCGCC
TCATCAGCCTGCTGAACCTGCACAAGAAGCGGCACTCGGGCGAGGCGCGCTACCGCTGCGAGGACTGCGGCAAGCTCTTCACCACCTCGG
GCAACCTCAAGCGCCACCAGCTGGTGCACAGCGGCGAGAAGCCCTACCAGTGCGACTACTGCGGCCGCTCCTTCTCCGACCCCACTTCCA
AGATGCGCCACCTGGAGACCCACGACACGGACAAGGAGCACAAGTGCCCACACTGCGACAAGAAGTTCAACCAGGTAGGGAACCTGAAGG
CCCACCTGAAGATCCACATCGCTGACGGGCCCCTCAAGTGCCGAGAGTGTGGGAAGCAGTTCACCACCTCAGGGAACCTGAAGCGGCACC
TTCGGATCCACAGCGGGGAGAAGCCCTACGTGTGCATCCACTGCCAGCGACAGTTTGCAGACCCCGGCGCTCTGCAGCGGCACGTCCGCA
TTCACACAGGTGAGAAGCCATGCCAGTGTGTGATGTGCGGTAAGGCCTTCACCCAGGCCAGCTCCCTCATCGCCCACGTGCGCCAGCACA
CCGGGGAGAAGCCCTACGTCTGCGAGCGCTGCGGCAAGAGATTCGTCCAGTCCAGCCAGTTGGCCAATCATATTCGCCACCACGACAACA
TCCGCCCACACAAGTGCAGCGTGTGCAGCAAGGCCTTCGTGAACGTGGGGGACCTGTCCAAGCACATCATCATTCACACTGCATTAATAA
TAAGCTACAGCAGCCGGAGGCAGCGGCCGGAGTGTTAGAATATGCCATGAAACACTTTGGAGAGCTGGAGATCCAGGCTACCTGGTATGA
GAAACTGCACGAGTGGGAGGATGCCCTTGTGGCCTATGACAAGAAAATGGACACCAACAAGGACGACCCAGAGCTGATGCTGGGCCGCAT
GCGCTGCCTCGAGGCCTTGGGGGAATGGGGTCAACTCCACCAGCAGTGCTGTGAAAAGTGGACCCTGGTTAATGATGAGACCCAAGCCAA
GATGGCCCGGATGGCTGCTGCAGCTGCATGGGGTTTAGGTCAGTGGGACAGCATGGAAGAATACACCTGTATGATCCCTCGGGACACCCA
TGATGGGGCATTTTATAGAGCTGTGCTGGCACTGCATCAGGACCTCTTCTCCTTGGCACAACAGTGCATTGACAAGGCCAGGGACCTGCT
GGATGCTGAATTAACTGCGATGGCAGGAGAGAGTTACAGTCGGGCATATGGGGCCATGGTTTCTTGCCACATGCTGTCCGAGCTGGAGGA
GGTTATCCAGTACAAACTTGTCCCCGAGCGACGAGAGATCATCCGCCAGATCTGGTGGGAGAGACTGCAGGGCTGCCAGCGTATCGTAGA
GGACTGGCAGAAAATCCTTATGGTGCGGTCCCTTGTGGTCAGCCCTCATGAAGACATGAGAACCTGGCTCAAGTATGCAAGCCTGTGCGG
CAAGAGTGGCAGGCTGGCTCTTGCTCATAAAACTTTAGTGTTGCTCCTGGGAGTTGATCCGTCTCGGCAACTTGACCATCCTCTGCCAAC
AGTTCACCCTCAGGTGACCTATGCCTACATGAAAAACATGTGGAAGAGTGCCCGCAAGATCGATGCCTTCCAGCACATGCAGCATTTTGT
CCAGACCATGCAGCAACAGGCCCAGCATGCCATCGCTACTGAGGACCAGCAGCATAAGCAGGAACTGCACAAGCTCATGGCCCGATGCTT
CCTGAAACTTGGAGAGTGGCAGCTGAATCTACAGGGCATCAATGAGAGCACAATCCCCAAAGTGCTGCAGTACTACAGCGCCGCCACAGA
GCACGACCGCAGCTGGTACAAGGCCTGGCATGCGTGGGCAGTGATGAACTTCGAAGCTGTGCTACACTACAAACATCAGAACCAAGCCCG
CGATGAGAAGAAGAAACTGCGTCATGCCAGCGGGGCCAACATCACCAACGCCACCACTGCCGCCACCACGGCCGCCACTGCCACCACCAC
TGCCAGCACCGAGGGCAGCAACAGTGAGAGCGAGGCCGAGAGCACCGAGAACAGCCCCACCCCATCGCCGCTGCAGAAGAAGGTCACTGA
GGATCTGTCCAAAACCCTCCTGATGTACACGGTGCCTGCCGTCCAGGGCTTCTTCCGTTCCATCTCCTTGTCACGAGGCAACAACCTCCA
GGATACACTCAGAGTTCTCACCTTATGGTTTGATTATGGTCACTGGCCAGATGTCAATGAGGCCTTAGTGGAGGGGGTGAAAGCCATCCA
GATTGATACCTGGCTACAGGTTATACCTCAGCTCATTGCAAGAATTGATACGCCCAGACCCTTGGTGGGACGTCTCATTCACCAGCTTCT
CACAGACATTGGTCGGTACCACCCCCAGGCCCTCATCTACCCACTGACAGTGGCTTCTAAGTCTACCACGACAGCCCGGCACAATGCAGC
CAACAAGATTCTGAAGAACATGTGTGAGCACAGCAACACCCTGGTCCAGCAGGCCATGATGGTGAGCGAGGAGCTGATCCGAGTGGCCAT
CCTCTGGCATGAGATGTGGCATGAAGGCCTGGAAGAGGCATCTCGTTTGTACTTTGGGGAAAGGAACGTGAAAGGCATGTTTGAGGTGCT
GGAGCCCTTGCATGCTATGATGGAACGGGGCCCCCAGACTCTGAAGGAAACATCCTTTAATCAGGCCTATGGTCGAGATTTAATGGAGGC
CCAAGAGTGGTGCAGGAAGTACATGAAATCAGGGAATGTCAAGGACCTCACCCAAGCCTGGGACCTCTATTATCATGTGTTCCGACGAAT
CTCAAAGCAGCTGCCTCAGCTCACATCCTTAGAGCTGCAATATGTTTCCCCAAAACTTCTGATGTGCCGGGACCTTGAATTGGCTGTGCC
AGGAACATATGACCCCAACCAGCCAATCATTCGCATTCAGTCCATAGCACCGTCTTTGCAAGTCATCACATCCAAGCAGAGGCCCCGGAA
ATTGACACTTATGGGCAGCAACGGACATGAGTTTGTTTTCCTTCTAAAAGGCCATGAAGATCTGCGCCAGGATGAGCGTGTGATGCAGCT
CTTCGGCCTGGTTAACACCCTTCTGGCCAATGACCCAACATCTCTTCGGAAAAACCTCAGCATCCAGAGATACGCTGTCATCCCTTTATC
GACCAACTCGGGCCTCATTGGCTGGGTTCCCCACTGTGACACACTGCACGCCCTCATCCGGGACTACAGGGAGAAGAAGAAGATCCTTCT
CAACATCGAGCATCGCATCATGTTGCGGATGGCTCCGGACTATGACCACTTGACTCTGATGCAGAAGGTGGAGGTGTTTGAGCATGCCGT
CAATAATACAGCTGGGGACGACCTGGCCAAGCTGCTGTGGCTGAAAAGCCCCAGCTCCGAGGTGTGGTTTGACCGAAGAACCAATTATAC
CCGTTCTTTAGCGGTCATGTCAATGGTTGGGTATATTTTAGGCCTGGGAGATAGACACCCATCCAACCTGATGCTGGACCGTCTGAGTGG
GAAGATCCTGCACATTGACTTTGGGGACTGCTTTGAGGTTGCTATGACCCGAGAGAAGTTTCCAGAGAAGATTCCATTTAGACTAACAAG
AATGTTGACCAATGCTATGGAGGTTACAGGCCTGGATGGCAACTACAGAATCACATGCCACACAGTGATGGAGGTGCTGCGAGAGCACAA
GGACAGTGTCATGGCCGTGCTGGAAGCCTTTGTCTATGACCCCTTGCTGAACTGGAGGCTGATGGACACAAATACCAAAGGCAACAAGCG
ATCCCGAACGAGGACGGATTCCTACTCTGCTGGCCAGTCAGTCGAAATTTTGGACGGTGTGGAACTTGGAGAGCCAGCCCATAAGAAAAC
GGGGACCACAGTGCCAGAATCTATTCATTCTTTCATTGGAGACGGTTTGGTGAAACCAGAGGCCCTAAATAAGAAAGCTATCCAGATTAT
TAACAGGGTTCGAGATAAGCTCACTGGTCGGGACTTCTCTCATGATGACACTTTGGATGTTCCAACGCAAGTTGAGCTGCTCATCAAACA
AGCGACATCCCATGAAAACCTCTGCCAGTGCTATATTGGCTGGTGCCCTTTCTGGTAACTGGAGGCCCAGATGTGCCCATCACGTTTTTT
CTGAGGCTTTTGTACTTTAGTAAATGCTTCCACTAAACTGAAACCATGGTGAGAAAGTTTGACTTTGTTAAATATTTTGAAATGTAAATG
AAAAGAACTACTGTATATTAAAAGTTGGTTTGAACCAACTTTCTAGCTGCTGTTGAAGAATATATTGTCAGAAACACAAGGCTTGATTTG
GTTCCCAGGACAGTGAAACATAGTAATACCACGTAAATCAAGCCATTCATTTTGGGGAACAGAAGATCCATAACTTTAGAAATACGGGTT
TTGACTTAACTCACAAGAGAACTCATCATAAGTACTTGCTGATGGAAGAATGACCTAGTTGCTCCTCTCAACATGGGTACAGCAAACTCA
GCACAGCCAAGAAGCCTCAGGTCGTGGAGAACATGGATTAGGATCCTAGACTGTAAAGACACAGAAGATGCTGACCTCACCCCTGCCACC
TATCCCAAGACCTCACTGGTCTGTGGACAGCAGCAGAAATGTTTGCAAGATAGGCCAAAATGAGTACAAAAGGTCTGTCTTCCATCAGAC
CCAGTGATGCTGCGACTCACACGCTTCAATTCAAGACCTGACCGCTAGTAGGGAGGTTTATTCAGATCGCTGGCAGCCTCGGCTGAGCAG
ATGCACAGAGGGGATCACTGTGCAGTGGGACCACCCTCACTGGCCTTCTGCAGCAGGGTTCTGGGATGTTTTCAGTGGTCAAAATACTCT
GTTTAGAGCAAGGGCTCAGAAAACAGAAATACTGTCATGGAGGTGCTGAACACAGGGAAGGTCTGGTACATATTGGAAATTATGAGCAGA
ACAAATACTCAACTAAATGCACAAAGTATAAAGTGTAGCCATGTCTAGACACCATGTTGTATCAGAATAATTTTTGTGCCAATAAATGAC

>In-frame_ENST00000375743_ENST00000361445_TCGA-BR-4357-01A_ZBTB17_chr1_16269559_-_MTOR_chr1_11227574_length(amino acids)=1182AA_start in transcript=1909_stop in transcript=5457
MRALRQEIRPVQPVGQSYSPPRQHPPTQVQRVQQGLRERGGPVQAHHHSHCINNKLQQPEAAAGVLEYAMKHFGELEIQATWYEKLHEWE
DALVAYDKKMDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEKWTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYR
AVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLVPERREIIRQIWWERLQGCQRIVEDWQKIL
MVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQLDHPLPTVHPQVTYAYMKNMWKSARKIDAFQHMQHFVQTMQQQ
AQHAIATEDQQHKQELHKLMARCFLKLGEWQLNLQGINESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEAVLHYKHQNQARDEKKKL
RHASGANITNATTAATTAATATTTASTEGSNSESEAESTENSPTPSPLQKKVTEDLSKTLLMYTVPAVQGFFRSISLSRGNNLQDTLRVL
TLWFDYGHWPDVNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANKILKN
MCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRK
YMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGS
NGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRI
MLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHID
FGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTD
SYSAGQSVEILDGVELGEPAHKKTGTTVPESIHSFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVELLIKQATSHEN

--------------------------------------------------------------
>In-frame_ENST00000537142_ENST00000361445_TCGA-BR-4357-01A_ZBTB17_chr1_16269559_-_MTOR_chr1_11227574_length(transcript)=6176nt_BP=1829nt
AACATGGCGGCGCCCTTTGTCTGCTCTGGAGTGCCGTCCCCGGCCTTCTCGCGGCCGTGATGCACCTCCCTCTGCGGTGGGGTCCGGGAC
ATGGCAGGTAATGAGCCGGACGAGGGGAGCCAAGCTGGAGTTTACACAGGCAAACTGTCAGAAAAGAGTAGCCTGGGCTGTCTGGAAATC
TGAGGCCTGGGGCAGGTGCTGGAGTTTATGTACACGGCCAAGCTGAGCCTGAGCCCTGAGAACGTGGATGATGTGCTGGCCGTGGCCACT
TTCCTCCAAATGCAGGACATCATCACGGCCTGCCATGCCCTCAAGTCACTTGCTGAGCCGGCTACCAGCCCTGGGGGAAATGCGGAGGCC
TTGGCCACAGAAGGTCTGCCCTGTTCCATCTCCAGGAGGGGACAAGAGAGCCAAAGAGGAGAAGGTGGCCACCAGCACGCTGAGCAGGCT
GGAGCAGGCAGGACGCAGCACACCCATAGGCCCCAGCAGGGACCTCAAGGAGGAGCGCGGCGGTCAGGCCCAGAGTGCGGCCAGCGGTGC
AGAGCAGACAGAGAAAGCCGATGCGCCCCGGGAGCCGCCGCCTGTGGAGCTCAAGCCAGACCCCACGAGTGGCATGGCTGCTGCAGAAGC
TGAGGCCGCTTTGTCCGAGAGCTCGGAGCAAGAAATGGAGGTGGAGCCCGCCCGGAAAGGGGAAGAGGAGCAAAAGGAGCAAGAGGAGCA
AGAGGAGGAGGGCGCAGGGCCAGCTGAGGTCAAGGAGGAGGGTTCCCAGCTGGAGAACGGAGAGGCCCCCGAGGAGAACGAGAATGAGGA
GTCAGCGGGCACAGACTCGGGGCAGGAGCTCGGCTCCGAGGCCCGGGGCCTGCGCTCAGGCACCTACGGCGACCGCACGGAGTCCAAGGC
CTACGGCTCCGTCATCCACAAGTGCGAGGACTGTGGGAAGGAGTTCACGCACACGGGGAACTTCAAGCGGCACATCCGCATCCACACGGG
GGAGAAGCCCTTCTCGTGCCGGGAGTGCAGCAAGGCCTTTTCCGACCCGGCCGCGTGCAAGGCCCATGAGAAGACGCACAGCCCTCTGAA
GCCCTACGGCTGCGAGGAGTGCGGGAAGAGCTACCGCCTCATCAGCCTGCTGAACCTGCACAAGAAGCGGCACTCGGGCGAGGCGCGCTA
CCGCTGCGAGGACTGCGGCAAGCTCTTCACCACCTCGGGCAACCTCAAGCGCCACCAGCTGGTGCACAGCGGCGAGAAGCCCTACCAGTG
CGACTACTGCGGCCGCTCCTTCTCCGACCCCACTTCCAAGATGCGCCACCTGGAGACCCACGACACGGACAAGGAGCACAAGTGCCCACA
CTGCGACAAGAAGTTCAACCAGGTAGGGAACCTGAAGGCCCACCTGAAGATCCACATCGCTGACGGGCCCCTCAAGTGCCGAGAGTGTGG
GAAGCAGTTCACCACCTCAGGGAACCTGAAGCGGCACCTTCGGATCCACAGCGGGGAGAAGCCCTACGTGTGCATCCACTGCCAGCGACA
GTTTGCAGACCCCGGCGCTCTGCAGCGGCACGTCCGCATTCACACAGGTGAGAAGCCATGCCAGTGTGTGATGTGCGGTAAGGCCTTCAC
CCAGGCCAGCTCCCTCATCGCCCACGTGCGCCAGCACACCGGGGAGAAGCCCTACGTCTGCGAGCGCTGCGGCAAGAGATTCGTCCAGTC
CAGCCAGTTGGCCAATCATATTCGCCACCACGACAACATCCGCCCACACAAGTGCAGCGTGTGCAGCAAGGCCTTCGTGAACGTGGGGGA
CCTGTCCAAGCACATCATCATTCACACTGCATTAATAATAAGCTACAGCAGCCGGAGGCAGCGGCCGGAGTGTTAGAATATGCCATGAAA
CACTTTGGAGAGCTGGAGATCCAGGCTACCTGGTATGAGAAACTGCACGAGTGGGAGGATGCCCTTGTGGCCTATGACAAGAAAATGGAC
ACCAACAAGGACGACCCAGAGCTGATGCTGGGCCGCATGCGCTGCCTCGAGGCCTTGGGGGAATGGGGTCAACTCCACCAGCAGTGCTGT
GAAAAGTGGACCCTGGTTAATGATGAGACCCAAGCCAAGATGGCCCGGATGGCTGCTGCAGCTGCATGGGGTTTAGGTCAGTGGGACAGC
ATGGAAGAATACACCTGTATGATCCCTCGGGACACCCATGATGGGGCATTTTATAGAGCTGTGCTGGCACTGCATCAGGACCTCTTCTCC
TTGGCACAACAGTGCATTGACAAGGCCAGGGACCTGCTGGATGCTGAATTAACTGCGATGGCAGGAGAGAGTTACAGTCGGGCATATGGG
GCCATGGTTTCTTGCCACATGCTGTCCGAGCTGGAGGAGGTTATCCAGTACAAACTTGTCCCCGAGCGACGAGAGATCATCCGCCAGATC
TGGTGGGAGAGACTGCAGGGCTGCCAGCGTATCGTAGAGGACTGGCAGAAAATCCTTATGGTGCGGTCCCTTGTGGTCAGCCCTCATGAA
GACATGAGAACCTGGCTCAAGTATGCAAGCCTGTGCGGCAAGAGTGGCAGGCTGGCTCTTGCTCATAAAACTTTAGTGTTGCTCCTGGGA
GTTGATCCGTCTCGGCAACTTGACCATCCTCTGCCAACAGTTCACCCTCAGGTGACCTATGCCTACATGAAAAACATGTGGAAGAGTGCC
CGCAAGATCGATGCCTTCCAGCACATGCAGCATTTTGTCCAGACCATGCAGCAACAGGCCCAGCATGCCATCGCTACTGAGGACCAGCAG
CATAAGCAGGAACTGCACAAGCTCATGGCCCGATGCTTCCTGAAACTTGGAGAGTGGCAGCTGAATCTACAGGGCATCAATGAGAGCACA
ATCCCCAAAGTGCTGCAGTACTACAGCGCCGCCACAGAGCACGACCGCAGCTGGTACAAGGCCTGGCATGCGTGGGCAGTGATGAACTTC
GAAGCTGTGCTACACTACAAACATCAGAACCAAGCCCGCGATGAGAAGAAGAAACTGCGTCATGCCAGCGGGGCCAACATCACCAACGCC
ACCACTGCCGCCACCACGGCCGCCACTGCCACCACCACTGCCAGCACCGAGGGCAGCAACAGTGAGAGCGAGGCCGAGAGCACCGAGAAC
AGCCCCACCCCATCGCCGCTGCAGAAGAAGGTCACTGAGGATCTGTCCAAAACCCTCCTGATGTACACGGTGCCTGCCGTCCAGGGCTTC
TTCCGTTCCATCTCCTTGTCACGAGGCAACAACCTCCAGGATACACTCAGAGTTCTCACCTTATGGTTTGATTATGGTCACTGGCCAGAT
GTCAATGAGGCCTTAGTGGAGGGGGTGAAAGCCATCCAGATTGATACCTGGCTACAGGTTATACCTCAGCTCATTGCAAGAATTGATACG
CCCAGACCCTTGGTGGGACGTCTCATTCACCAGCTTCTCACAGACATTGGTCGGTACCACCCCCAGGCCCTCATCTACCCACTGACAGTG
GCTTCTAAGTCTACCACGACAGCCCGGCACAATGCAGCCAACAAGATTCTGAAGAACATGTGTGAGCACAGCAACACCCTGGTCCAGCAG
GCCATGATGGTGAGCGAGGAGCTGATCCGAGTGGCCATCCTCTGGCATGAGATGTGGCATGAAGGCCTGGAAGAGGCATCTCGTTTGTAC
TTTGGGGAAAGGAACGTGAAAGGCATGTTTGAGGTGCTGGAGCCCTTGCATGCTATGATGGAACGGGGCCCCCAGACTCTGAAGGAAACA
TCCTTTAATCAGGCCTATGGTCGAGATTTAATGGAGGCCCAAGAGTGGTGCAGGAAGTACATGAAATCAGGGAATGTCAAGGACCTCACC
CAAGCCTGGGACCTCTATTATCATGTGTTCCGACGAATCTCAAAGCAGCTGCCTCAGCTCACATCCTTAGAGCTGCAATATGTTTCCCCA
AAACTTCTGATGTGCCGGGACCTTGAATTGGCTGTGCCAGGAACATATGACCCCAACCAGCCAATCATTCGCATTCAGTCCATAGCACCG
TCTTTGCAAGTCATCACATCCAAGCAGAGGCCCCGGAAATTGACACTTATGGGCAGCAACGGACATGAGTTTGTTTTCCTTCTAAAAGGC
CATGAAGATCTGCGCCAGGATGAGCGTGTGATGCAGCTCTTCGGCCTGGTTAACACCCTTCTGGCCAATGACCCAACATCTCTTCGGAAA
AACCTCAGCATCCAGAGATACGCTGTCATCCCTTTATCGACCAACTCGGGCCTCATTGGCTGGGTTCCCCACTGTGACACACTGCACGCC
CTCATCCGGGACTACAGGGAGAAGAAGAAGATCCTTCTCAACATCGAGCATCGCATCATGTTGCGGATGGCTCCGGACTATGACCACTTG
ACTCTGATGCAGAAGGTGGAGGTGTTTGAGCATGCCGTCAATAATACAGCTGGGGACGACCTGGCCAAGCTGCTGTGGCTGAAAAGCCCC
AGCTCCGAGGTGTGGTTTGACCGAAGAACCAATTATACCCGTTCTTTAGCGGTCATGTCAATGGTTGGGTATATTTTAGGCCTGGGAGAT
AGACACCCATCCAACCTGATGCTGGACCGTCTGAGTGGGAAGATCCTGCACATTGACTTTGGGGACTGCTTTGAGGTTGCTATGACCCGA
GAGAAGTTTCCAGAGAAGATTCCATTTAGACTAACAAGAATGTTGACCAATGCTATGGAGGTTACAGGCCTGGATGGCAACTACAGAATC
ACATGCCACACAGTGATGGAGGTGCTGCGAGAGCACAAGGACAGTGTCATGGCCGTGCTGGAAGCCTTTGTCTATGACCCCTTGCTGAAC
TGGAGGCTGATGGACACAAATACCAAAGGCAACAAGCGATCCCGAACGAGGACGGATTCCTACTCTGCTGGCCAGTCAGTCGAAATTTTG
GACGGTGTGGAACTTGGAGAGCCAGCCCATAAGAAAACGGGGACCACAGTGCCAGAATCTATTCATTCTTTCATTGGAGACGGTTTGGTG
AAACCAGAGGCCCTAAATAAGAAAGCTATCCAGATTATTAACAGGGTTCGAGATAAGCTCACTGGTCGGGACTTCTCTCATGATGACACT
TTGGATGTTCCAACGCAAGTTGAGCTGCTCATCAAACAAGCGACATCCCATGAAAACCTCTGCCAGTGCTATATTGGCTGGTGCCCTTTC
TGGTAACTGGAGGCCCAGATGTGCCCATCACGTTTTTTCTGAGGCTTTTGTACTTTAGTAAATGCTTCCACTAAACTGAAACCATGGTGA
GAAAGTTTGACTTTGTTAAATATTTTGAAATGTAAATGAAAAGAACTACTGTATATTAAAAGTTGGTTTGAACCAACTTTCTAGCTGCTG
TTGAAGAATATATTGTCAGAAACACAAGGCTTGATTTGGTTCCCAGGACAGTGAAACATAGTAATACCACGTAAATCAAGCCATTCATTT
TGGGGAACAGAAGATCCATAACTTTAGAAATACGGGTTTTGACTTAACTCACAAGAGAACTCATCATAAGTACTTGCTGATGGAAGAATG
ACCTAGTTGCTCCTCTCAACATGGGTACAGCAAACTCAGCACAGCCAAGAAGCCTCAGGTCGTGGAGAACATGGATTAGGATCCTAGACT
GTAAAGACACAGAAGATGCTGACCTCACCCCTGCCACCTATCCCAAGACCTCACTGGTCTGTGGACAGCAGCAGAAATGTTTGCAAGATA
GGCCAAAATGAGTACAAAAGGTCTGTCTTCCATCAGACCCAGTGATGCTGCGACTCACACGCTTCAATTCAAGACCTGACCGCTAGTAGG
GAGGTTTATTCAGATCGCTGGCAGCCTCGGCTGAGCAGATGCACAGAGGGGATCACTGTGCAGTGGGACCACCCTCACTGGCCTTCTGCA
GCAGGGTTCTGGGATGTTTTCAGTGGTCAAAATACTCTGTTTAGAGCAAGGGCTCAGAAAACAGAAATACTGTCATGGAGGTGCTGAACA
CAGGGAAGGTCTGGTACATATTGGAAATTATGAGCAGAACAAATACTCAACTAAATGCACAAAGTATAAAGTGTAGCCATGTCTAGACAC

>In-frame_ENST00000537142_ENST00000361445_TCGA-BR-4357-01A_ZBTB17_chr1_16269559_-_MTOR_chr1_11227574_length(amino acids)=1182AA_start in transcript=1677_stop in transcript=5225
MRALRQEIRPVQPVGQSYSPPRQHPPTQVQRVQQGLRERGGPVQAHHHSHCINNKLQQPEAAAGVLEYAMKHFGELEIQATWYEKLHEWE
DALVAYDKKMDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEKWTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYR
AVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLVPERREIIRQIWWERLQGCQRIVEDWQKIL
MVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQLDHPLPTVHPQVTYAYMKNMWKSARKIDAFQHMQHFVQTMQQQ
AQHAIATEDQQHKQELHKLMARCFLKLGEWQLNLQGINESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEAVLHYKHQNQARDEKKKL
RHASGANITNATTAATTAATATTTASTEGSNSESEAESTENSPTPSPLQKKVTEDLSKTLLMYTVPAVQGFFRSISLSRGNNLQDTLRVL
TLWFDYGHWPDVNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANKILKN
MCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRK
YMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGS
NGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRI
MLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHID
FGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTD
SYSAGQSVEILDGVELGEPAHKKTGTTVPESIHSFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVELLIKQATSHEN

--------------------------------------------------------------
>In-frame_ENST00000375733_ENST00000361445_TCGA-BR-4357-01A_ZBTB17_chr1_16269559_-_MTOR_chr1_11227574_length(transcript)=6414nt_BP=2067nt
ATGCGCCGGAAGTTGCAGCCGGGAAGCCTGCGAGGTCGGTTCCGCCCGACTCTAACATGGCGGCGCCCTTTGTCTGCTCTGGAGTGCCGT
CCCCGGCCTTCTCGCGGCCGTGATGCACCTCCCTCTGCGGTGGGGTCCGGGACATGGCAGGTAATGAGCCGGACGAGGGGAGCCAAGCTG
GAGTTTACACAGGCAAACTGTCAGAAAAGAGTAGCCTGGGCTGTCTGGAAATCTGAGCCATGGACTTTCCCCAGCACAGCCAGCATGTCT
TGGAACAGCTGAACCAGCAGCGGCAGCTGGGGCTTCTCTGTGACTGCACCTTTGTGGTGGACGGTGTTCACTTTAAGGCTCATAAAGCAG
TGCTGGCGGCCTGCAGCGAGTACTTCAAGATGCTCTTCGTGGACCAGAAGGACGTGGTGCACCTGGACATCAGTAACGCGGCAGGCCTGG
GGCAGGTGCTGGAGTTTATGTACACGGCCAAGCTGAGCCTGAGCCCTGAGAACGTGGATGATGTGCTGGCCGTGGCCACTTTCCTCCAAA
TGCAGGACATCATCACGGCCTGCCATGCCCTCAAGTCACTTGCTGAGCCGGCTACCAGCCCTGGGGGAAATGCGGAGGCCTTGGCCACAG
AAGGAGGGGACAAGAGAGCCAAAGAGGAGAAGGTGGCCACCAGCACGCTGAGCAGGCTGGAGCAGGCAGGACGCAGCACACCCATAGGCC
CCAGCAGGGACCTCAAGGAGGAGCGCGGCGGTCAGGCCCAGAGTGCGGCCAGCGGTGCAGAGCAGACAGAGAAAGCCGATGCGCCCCGGG
AGCCGCCGCCTGTGGAGCTCAAGCCAGACCCCACGAGTGGCATGGCTGCTGCAGAAGCTGAGGCCGCTTTGTCCGAGAGCTCGGAGCAAG
AAATGGAGGTGGAGCCCGCCCGGAAAGGGGAAGAGGAGCAAAAGGAGCAAGAGGAGCAAGAGGAGGAGGGCGCAGGGCCAGCTGAGGTCA
AGGAGGAGGGTTCCCAGCTGGAGAACGGAGAGGCCCCCGAGGAGAACGAGAATGAGGAGTCAGCGGGCACAGACTCGGGGCAGGAGCTCG
GCTCCGAGGCCCGGGGCCTGCGCTCAGGCACCTACGGCGACCGCACGGAGTCCAAGGCCTACGGCTCCGTCATCCACAAGTGCGAGGACT
GTGGGAAGGAGTTCACGCACACGGGGAACTTCAAGCGGCACATCCGCATCCACACGGGGGAGAAGCCCTTCTCGTGCCGGGAGTGCAGCA
AGGCCTTTTCCGACCCGGCCGCGTGCAAGGCCCATGAGAAGACGCACAGCCCTCTGAAGCCCTACGGCTGCGAGGAGTGCGGGAAGAGCT
ACCGCCTCATCAGCCTGCTGAACCTGCACAAGAAGCGGCACTCGGGCGAGGCGCGCTACCGCTGCGAGGACTGCGGCAAGCTCTTCACCA
CCTCGGGCAACCTCAAGCGCCACCAGCTGGTGCACAGCGGCGAGAAGCCCTACCAGTGCGACTACTGCGGCCGCTCCTTCTCCGACCCCA
CTTCCAAGATGCGCCACCTGGAGACCCACGACACGGACAAGGAGCACAAGTGCCCACACTGCGACAAGAAGTTCAACCAGGTAGGGAACC
TGAAGGCCCACCTGAAGATCCACATCGCTGACGGGCCCCTCAAGTGCCGAGAGTGTGGGAAGCAGTTCACCACCTCAGGGAACCTGAAGC
GGCACCTTCGGATCCACAGCGGGGAGAAGCCCTACGTGTGCATCCACTGCCAGCGACAGTTTGCAGACCCCGGCGCTCTGCAGCGGCACG
TCCGCATTCACACAGGTGAGAAGCCATGCCAGTGTGTGATGTGCGGTAAGGCCTTCACCCAGGCCAGCTCCCTCATCGCCCACGTGCGCC
AGCACACCGGGGAGAAGCCCTACGTCTGCGAGCGCTGCGGCAAGAGATTCGTCCAGTCCAGCCAGTTGGCCAATCATATTCGCCACCACG
ACAACATCCGCCCACACAAGTGCAGCGTGTGCAGCAAGGCCTTCGTGAACGTGGGGGACCTGTCCAAGCACATCATCATTCACACTGCAT
TAATAATAAGCTACAGCAGCCGGAGGCAGCGGCCGGAGTGTTAGAATATGCCATGAAACACTTTGGAGAGCTGGAGATCCAGGCTACCTG
GTATGAGAAACTGCACGAGTGGGAGGATGCCCTTGTGGCCTATGACAAGAAAATGGACACCAACAAGGACGACCCAGAGCTGATGCTGGG
CCGCATGCGCTGCCTCGAGGCCTTGGGGGAATGGGGTCAACTCCACCAGCAGTGCTGTGAAAAGTGGACCCTGGTTAATGATGAGACCCA
AGCCAAGATGGCCCGGATGGCTGCTGCAGCTGCATGGGGTTTAGGTCAGTGGGACAGCATGGAAGAATACACCTGTATGATCCCTCGGGA
CACCCATGATGGGGCATTTTATAGAGCTGTGCTGGCACTGCATCAGGACCTCTTCTCCTTGGCACAACAGTGCATTGACAAGGCCAGGGA
CCTGCTGGATGCTGAATTAACTGCGATGGCAGGAGAGAGTTACAGTCGGGCATATGGGGCCATGGTTTCTTGCCACATGCTGTCCGAGCT
GGAGGAGGTTATCCAGTACAAACTTGTCCCCGAGCGACGAGAGATCATCCGCCAGATCTGGTGGGAGAGACTGCAGGGCTGCCAGCGTAT
CGTAGAGGACTGGCAGAAAATCCTTATGGTGCGGTCCCTTGTGGTCAGCCCTCATGAAGACATGAGAACCTGGCTCAAGTATGCAAGCCT
GTGCGGCAAGAGTGGCAGGCTGGCTCTTGCTCATAAAACTTTAGTGTTGCTCCTGGGAGTTGATCCGTCTCGGCAACTTGACCATCCTCT
GCCAACAGTTCACCCTCAGGTGACCTATGCCTACATGAAAAACATGTGGAAGAGTGCCCGCAAGATCGATGCCTTCCAGCACATGCAGCA
TTTTGTCCAGACCATGCAGCAACAGGCCCAGCATGCCATCGCTACTGAGGACCAGCAGCATAAGCAGGAACTGCACAAGCTCATGGCCCG
ATGCTTCCTGAAACTTGGAGAGTGGCAGCTGAATCTACAGGGCATCAATGAGAGCACAATCCCCAAAGTGCTGCAGTACTACAGCGCCGC
CACAGAGCACGACCGCAGCTGGTACAAGGCCTGGCATGCGTGGGCAGTGATGAACTTCGAAGCTGTGCTACACTACAAACATCAGAACCA
AGCCCGCGATGAGAAGAAGAAACTGCGTCATGCCAGCGGGGCCAACATCACCAACGCCACCACTGCCGCCACCACGGCCGCCACTGCCAC
CACCACTGCCAGCACCGAGGGCAGCAACAGTGAGAGCGAGGCCGAGAGCACCGAGAACAGCCCCACCCCATCGCCGCTGCAGAAGAAGGT
CACTGAGGATCTGTCCAAAACCCTCCTGATGTACACGGTGCCTGCCGTCCAGGGCTTCTTCCGTTCCATCTCCTTGTCACGAGGCAACAA
CCTCCAGGATACACTCAGAGTTCTCACCTTATGGTTTGATTATGGTCACTGGCCAGATGTCAATGAGGCCTTAGTGGAGGGGGTGAAAGC
CATCCAGATTGATACCTGGCTACAGGTTATACCTCAGCTCATTGCAAGAATTGATACGCCCAGACCCTTGGTGGGACGTCTCATTCACCA
GCTTCTCACAGACATTGGTCGGTACCACCCCCAGGCCCTCATCTACCCACTGACAGTGGCTTCTAAGTCTACCACGACAGCCCGGCACAA
TGCAGCCAACAAGATTCTGAAGAACATGTGTGAGCACAGCAACACCCTGGTCCAGCAGGCCATGATGGTGAGCGAGGAGCTGATCCGAGT
GGCCATCCTCTGGCATGAGATGTGGCATGAAGGCCTGGAAGAGGCATCTCGTTTGTACTTTGGGGAAAGGAACGTGAAAGGCATGTTTGA
GGTGCTGGAGCCCTTGCATGCTATGATGGAACGGGGCCCCCAGACTCTGAAGGAAACATCCTTTAATCAGGCCTATGGTCGAGATTTAAT
GGAGGCCCAAGAGTGGTGCAGGAAGTACATGAAATCAGGGAATGTCAAGGACCTCACCCAAGCCTGGGACCTCTATTATCATGTGTTCCG
ACGAATCTCAAAGCAGCTGCCTCAGCTCACATCCTTAGAGCTGCAATATGTTTCCCCAAAACTTCTGATGTGCCGGGACCTTGAATTGGC
TGTGCCAGGAACATATGACCCCAACCAGCCAATCATTCGCATTCAGTCCATAGCACCGTCTTTGCAAGTCATCACATCCAAGCAGAGGCC
CCGGAAATTGACACTTATGGGCAGCAACGGACATGAGTTTGTTTTCCTTCTAAAAGGCCATGAAGATCTGCGCCAGGATGAGCGTGTGAT
GCAGCTCTTCGGCCTGGTTAACACCCTTCTGGCCAATGACCCAACATCTCTTCGGAAAAACCTCAGCATCCAGAGATACGCTGTCATCCC
TTTATCGACCAACTCGGGCCTCATTGGCTGGGTTCCCCACTGTGACACACTGCACGCCCTCATCCGGGACTACAGGGAGAAGAAGAAGAT
CCTTCTCAACATCGAGCATCGCATCATGTTGCGGATGGCTCCGGACTATGACCACTTGACTCTGATGCAGAAGGTGGAGGTGTTTGAGCA
TGCCGTCAATAATACAGCTGGGGACGACCTGGCCAAGCTGCTGTGGCTGAAAAGCCCCAGCTCCGAGGTGTGGTTTGACCGAAGAACCAA
TTATACCCGTTCTTTAGCGGTCATGTCAATGGTTGGGTATATTTTAGGCCTGGGAGATAGACACCCATCCAACCTGATGCTGGACCGTCT
GAGTGGGAAGATCCTGCACATTGACTTTGGGGACTGCTTTGAGGTTGCTATGACCCGAGAGAAGTTTCCAGAGAAGATTCCATTTAGACT
AACAAGAATGTTGACCAATGCTATGGAGGTTACAGGCCTGGATGGCAACTACAGAATCACATGCCACACAGTGATGGAGGTGCTGCGAGA
GCACAAGGACAGTGTCATGGCCGTGCTGGAAGCCTTTGTCTATGACCCCTTGCTGAACTGGAGGCTGATGGACACAAATACCAAAGGCAA
CAAGCGATCCCGAACGAGGACGGATTCCTACTCTGCTGGCCAGTCAGTCGAAATTTTGGACGGTGTGGAACTTGGAGAGCCAGCCCATAA
GAAAACGGGGACCACAGTGCCAGAATCTATTCATTCTTTCATTGGAGACGGTTTGGTGAAACCAGAGGCCCTAAATAAGAAAGCTATCCA
GATTATTAACAGGGTTCGAGATAAGCTCACTGGTCGGGACTTCTCTCATGATGACACTTTGGATGTTCCAACGCAAGTTGAGCTGCTCAT
CAAACAAGCGACATCCCATGAAAACCTCTGCCAGTGCTATATTGGCTGGTGCCCTTTCTGGTAACTGGAGGCCCAGATGTGCCCATCACG
TTTTTTCTGAGGCTTTTGTACTTTAGTAAATGCTTCCACTAAACTGAAACCATGGTGAGAAAGTTTGACTTTGTTAAATATTTTGAAATG
TAAATGAAAAGAACTACTGTATATTAAAAGTTGGTTTGAACCAACTTTCTAGCTGCTGTTGAAGAATATATTGTCAGAAACACAAGGCTT
GATTTGGTTCCCAGGACAGTGAAACATAGTAATACCACGTAAATCAAGCCATTCATTTTGGGGAACAGAAGATCCATAACTTTAGAAATA
CGGGTTTTGACTTAACTCACAAGAGAACTCATCATAAGTACTTGCTGATGGAAGAATGACCTAGTTGCTCCTCTCAACATGGGTACAGCA
AACTCAGCACAGCCAAGAAGCCTCAGGTCGTGGAGAACATGGATTAGGATCCTAGACTGTAAAGACACAGAAGATGCTGACCTCACCCCT
GCCACCTATCCCAAGACCTCACTGGTCTGTGGACAGCAGCAGAAATGTTTGCAAGATAGGCCAAAATGAGTACAAAAGGTCTGTCTTCCA
TCAGACCCAGTGATGCTGCGACTCACACGCTTCAATTCAAGACCTGACCGCTAGTAGGGAGGTTTATTCAGATCGCTGGCAGCCTCGGCT
GAGCAGATGCACAGAGGGGATCACTGTGCAGTGGGACCACCCTCACTGGCCTTCTGCAGCAGGGTTCTGGGATGTTTTCAGTGGTCAAAA
TACTCTGTTTAGAGCAAGGGCTCAGAAAACAGAAATACTGTCATGGAGGTGCTGAACACAGGGAAGGTCTGGTACATATTGGAAATTATG
AGCAGAACAAATACTCAACTAAATGCACAAAGTATAAAGTGTAGCCATGTCTAGACACCATGTTGTATCAGAATAATTTTTGTGCCAATA

>In-frame_ENST00000375733_ENST00000361445_TCGA-BR-4357-01A_ZBTB17_chr1_16269559_-_MTOR_chr1_11227574_length(amino acids)=1182AA_start in transcript=1915_stop in transcript=5463
MRALRQEIRPVQPVGQSYSPPRQHPPTQVQRVQQGLRERGGPVQAHHHSHCINNKLQQPEAAAGVLEYAMKHFGELEIQATWYEKLHEWE
DALVAYDKKMDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEKWTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYR
AVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLVPERREIIRQIWWERLQGCQRIVEDWQKIL
MVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQLDHPLPTVHPQVTYAYMKNMWKSARKIDAFQHMQHFVQTMQQQ
AQHAIATEDQQHKQELHKLMARCFLKLGEWQLNLQGINESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEAVLHYKHQNQARDEKKKL
RHASGANITNATTAATTAATATTTASTEGSNSESEAESTENSPTPSPLQKKVTEDLSKTLLMYTVPAVQGFFRSISLSRGNNLQDTLRVL
TLWFDYGHWPDVNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANKILKN
MCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRK
YMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGS
NGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRI
MLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHID
FGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTD
SYSAGQSVEILDGVELGEPAHKKTGTTVPESIHSFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVELLIKQATSHEN

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Fusion Gene PPI Analysis for ZBTB17-MTOR


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375733-1316269_308609.3333333333334811.0MYC
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375743-1316269_308609.3333333333334804.0MYC
HgeneZBTB17chr1:16269559chr1:11227574ENST00000537142-1215269_308527.3333333333334722.0MYC
TgeneMTORchr1:16269559chr1:11227574ENST0000036144527582258_22961417.66666666666672550.0MLST8


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375733-1316637_803609.3333333333334811.0HCFC1
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375743-1316637_803609.3333333333334804.0HCFC1
HgeneZBTB17chr1:16269559chr1:11227574ENST00000537142-1215637_803527.3333333333334722.0HCFC1
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375733-1316637_718609.3333333333334811.0MYC
HgeneZBTB17chr1:16269559chr1:11227574ENST00000375743-1316637_718609.3333333333334804.0MYC
HgeneZBTB17chr1:16269559chr1:11227574ENST00000537142-1215637_718527.3333333333334722.0MYC
TgeneMTORchr1:16269559chr1:11227574ENST0000036144527581_6511417.66666666666672550.0NBN


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ZBTB17-MTOR


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ZBTB17-MTOR


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneMTORC1846385FOCAL CORTICAL DYSPLASIA OF TAYLOR5CTD_human;GENOMICS_ENGLAND;UNIPROT
TgeneMTORC4225259SMITH-KINGSMORE SYNDROME5GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneMTORC0041696Unipolar Depression2PSYGENET
TgeneMTORC0919267ovarian neoplasm2CTD_human
TgeneMTORC1140680Malignant neoplasm of ovary2CTD_human
TgeneMTORC1269683Major Depressive Disorder2PSYGENET
TgeneMTORC0001418Adenocarcinoma1CTD_human
TgeneMTORC0006142Malignant neoplasm of breast1CTD_human
TgeneMTORC0007102Malignant tumor of colon1CTD_human
TgeneMTORC0007131Non-Small Cell Lung Carcinoma1CTD_human
TgeneMTORC0007134Renal Cell Carcinoma1CTD_human
TgeneMTORC0007873Uterine Cervical Neoplasm1CTD_human
TgeneMTORC0009375Colonic Neoplasms1CTD_human
TgeneMTORC0014130Endocrine System Diseases1CTD_human
TgeneMTORC0017636Glioblastoma1CTD_human
TgeneMTORC0020538Hypertensive disease1CTD_human
TgeneMTORC0024232Lymphatic Metastasis1CTD_human
TgeneMTORC0025500Mesothelioma1CTD_human
TgeneMTORC0034069Pulmonary Fibrosis1CTD_human
TgeneMTORC0036341Schizophrenia1CTD_human
TgeneMTORC0149504Encephalopathy, Toxic1CTD_human
TgeneMTORC0149721Left Ventricular Hypertrophy1CTD_human
TgeneMTORC0154659Toxic Encephalitis1CTD_human
TgeneMTORC0205641Adenocarcinoma, Basal Cell1CTD_human
TgeneMTORC0205642Adenocarcinoma, Oxyphilic1CTD_human
TgeneMTORC0205643Carcinoma, Cribriform1CTD_human
TgeneMTORC0205644Carcinoma, Granular Cell1CTD_human
TgeneMTORC0205645Adenocarcinoma, Tubular1CTD_human
TgeneMTORC0235032Neurotoxicity Syndromes1CTD_human
TgeneMTORC0262584Carcinoma, Small Cell1CTD_human
TgeneMTORC0267963Exocrine pancreatic insufficiency1CTD_human
TgeneMTORC0279702Conventional (Clear Cell) Renal Cell Carcinoma1CGI;CTD_human
TgeneMTORC0334588Giant Cell Glioblastoma1CTD_human
TgeneMTORC0334634Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse1CTD_human
TgeneMTORC0431380Cortical Dysplasia1CTD_human
TgeneMTORC0431391Hemimegalencephaly1GENOMICS_ENGLAND
TgeneMTORC0543888Epileptic encephalopathy1GENOMICS_ENGLAND
TgeneMTORC0588006Mild depression1PSYGENET
TgeneMTORC0678222Breast Carcinoma1CTD_human
TgeneMTORC0751958Lymphoma, Lymphocytic, Intermediate1CTD_human
TgeneMTORC1257931Mammary Neoplasms, Human1CTD_human
TgeneMTORC1266042Chromophobe Renal Cell Carcinoma1CTD_human
TgeneMTORC1266043Sarcomatoid Renal Cell Carcinoma1CTD_human
TgeneMTORC1266044Collecting Duct Carcinoma of the Kidney1CTD_human
TgeneMTORC1306837Papillary Renal Cell Carcinoma1CTD_human
TgeneMTORC1458155Mammary Neoplasms1CTD_human
TgeneMTORC1621958Glioblastoma Multiforme1CTD_human;UNIPROT
TgeneMTORC1955869Malformations of Cortical Development1CTD_human
TgeneMTORC1961099Precursor T-Cell Lymphoblastic Leukemia-Lymphoma1CTD_human
TgeneMTORC2239176Liver carcinoma1CTD_human
TgeneMTORC3714756Intellectual Disability1GENOMICS_ENGLAND
TgeneMTORC4048328cervical cancer1CTD_human
TgeneMTORC4704874Mammary Carcinoma, Human1CTD_human
TgeneMTORC4721507Alveolitis, Fibrosing1CTD_human