Home

Download

Statistics

Examples

About

Contact

	Fusion Gene Summary
	Fusion Gene Breakpoints
	Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Geness
	Fusion Genomic Features
	Fusion Gene ORF Annotations
	Fusion Protein Retained/Non-Retained Functional Features
	Fusion Transcript Sequences
	Fusion Protein Sequences
	Personalized Fusion Protein Sequences
	Fusion Gene Expressed Samples
	Related Drugs

Fusion gene:FAM102B_TRAPPC8 (FusionGDB2 ID:HG284611TG22878)

Fusion Gene Summary for FAM102B_TRAPPC8

Fusion gene summary

Fusion gene information	Fusion gene name: FAM102B_TRAPPC8
	Fusion gene ID: hg284611tg22878
		Hgene	Tgene
	Gene symbol	FAM102B	TRAPPC8
	Gene ID	284611	22878
	Gene name	EEIG family member 2	trafficking protein particle complex subunit 8
	Synonyms	FAM102B\|SYM-3B	GSG1\|HsT2706\|KIAA1012\|TRS85
	Cytomap	1p13.3	18q12.1
	Type of gene	protein-coding	protein-coding
	Description	EEIG family member 2family with sequence similarity 102 member Bprotein FAM102Bsym-3 homolog B	trafficking protein particle complex subunit 8general sporulation gene 1 homologprotein TRS85 homologtrafficking protein particle complex 8
	Modification date	20240305	20240403
	UniProtAcc	Q5T8I3	.
	Ensembl transtripts involved in fusion gene	ENST00000370035, ENST00000405454,
Fusion gene scores	* DoF score	* DoF score (Degree of Frequency) = # partners X # break points X # disease types 7 X 5 X 6=210	* DoF score (Degree of Frequency) = # partners X # break points X # disease types 6 X 10 X 7=420
	# samples	11	10
	** MAII score	** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score10) log2(11/21010)=-0.932885804141463 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score10) log2(10/42010)=-2.0703893278914 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: FAM102B [Title/Abstract] AND TRAPPC8 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	FAM102B(109148874)-TRAPPC8(29419420), # samples:1

Fusion gene breakpoints across FAM102B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across TRAPPC8 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Top

Fusion Gene Breakpoints for FAM102B_TRAPPC8

RNA-seq based exon junction arranged fusion gene breakpoints from 8 resources (TCGA, CCLE, cBioPortal, GenBank, ChimerDB, ChimerKB, ChildHoodFusions, and GTEx). For the expressed sample information, go to Fusion Gene Sample section.

Hgene	Hchr	Hbp	Tgene	Tchr	Tbp
FAM102B	chr1	109148874	TRAPPC8	chr18	29419420
EEIG2	chr1	108606252	TRAPPC8	chr18	31839457

DNA-seq based exon junction arranged fusion gene breakpoints from dbVar. For the expressed sample information, go to Fusion Gene Sample section.

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

SV type

Top

Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Genes for FAM102B_TRAPPC8

To generate these tumorigenic scenario annotations, we implemented a deduction-first, retrieval-later computational framework. The pipeline first applies rule-guided reasoning across ten core mechanistic categories (M1–M10) derived from fusion gene biology to infer candidate mechanisms, tumorigenic scenarios, targeting points, and targeting backgrounds. To ensure empirical accountability, a governed Python workflow retrieves literature candidates via NCBI E-utilities and Europe PMC using tiered searches. Using JSON Schema-constrained LLM evidence judges (GPT-5.6 Luna and Terra), retrieved articles are evaluated for specificity and confidence without de novo PMID generation. This produces two distinct versions: a strict version restricted to high- or medium-confidence fusion-specific evidence, and an extended version incorporating broader gene-, pathway-, and contextual evidence.

* We have 10 tumorigenic mechanism categories of fusion genes as shown below.

Constitutively Active Kinases, Catalytic Domain Dysregulation, & Transmembrane Ligand Fusions	Aberrant Chimeric Transcription Factor / Fusion Transcription Factor Activity	Epigenetic Reprogramming / Histone Modifier Dysregulation	Chromatin Remodeling Dysregulation	Condensate-Driven Transcriptional Rewiring / LLP	Promoter / Enhancer Hijacking	Dominant-Negative Antagonism	Cell Cycle / Checkpoint Bypass / RNA Processing Dysregulation	Subcellular Mislocalization / Spatial Dysregulation	Nuclear Body / Sub-organellar Architecture Disruption & Differentiation Blockade

* Strict version: Restricted to high- or medium-confidence fusion-specific evidence.

Fusion Gene Name

Mechanism Category

Mechanism PubMed

Tumorigenic Scenarios

Tumorigenic Scenario PubMed

Targeting Points

Targeting PubMed

Mechanism Background

Mechanism Background PubMed

* Extended version: Includes all strict-level fusion evidence plus broader gene-, pathway-, and low-confidence contextual evidence.

Fusion Gene Name

Mechanism Category

Mechanism PubMed

Tumorigenic Scenarios

Tumorigenic Scenario PubMed

Targeting Points

Targeting PubMed

Mechanism Background

Mechanism Background PubMed

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
FAM102B Q5T8I3	.

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Top

Fusion Genomic Features for FAM102B_TRAPPC8

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of In-frame fusion genes. FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
FAM102B	chr1	109148874	+	TRAPPC8	chr18	29419420	-	5.45e-04	9.99e-01
FAM102B	chr1	109148874	-	TRAPPC8	chr18	29419420	-	1.26e-02	9.87e-01

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5UTR-3CSD fusion genes (N-truncated cases).

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5CDS-3UTR fusion genes (C-truncated cases).

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of six genomic regulatory feature tracks across a ±5 kb window centered on the fusion breakpoints. We input the breakpoint sequences into AlphaGenome and obtained predicted genome tracks at single-base-pair resolution for each modality by running a single forward pass over the reference sequence. Specifically, for each breakpoint, AlphaGenome processed and returned predicted track data across diverse modalities, which were then averaged across all tracks within each output type and visualized across the ±5 kb window. The left panel shows the 5'-gene breakpoint ±5 kb area, and the right panel shows the 3'-gene breakpoint area, with tracks grouped by category: chromatin accessibility (DNase-seq, ATAC-seq), active transcription (RNA-seq, CAGE), and chromatin binding (ChIP-Histone, ChIP-TF).

Top

Fusion Gene ORF Annotations for FAM102B_TRAPPC8

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
In-frame	ENST00000370035	ENST00000283351	FAM102B	chr1	109148874	-	TRAPPC8	chr18	29419420	-
In-frame	ENST00000370035	ENST00000582539	FAM102B	chr1	109148874	-	TRAPPC8	chr18	29419420	-
In-frame	ENST00000405454	ENST00000283351	FAM102B	chr1	109148874	-	TRAPPC8	chr18	29419420	-
In-frame	ENST00000405454	ENST00000582539	FAM102B	chr1	109148874	-	TRAPPC8	chr18	29419420	-

ORFfinder Result Based On The Fusion Transcript Sequences of the In-frame Fusion Genes.

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	Seq length (transcript)	Seq length (peptide)
ENST00000370035	ENST00000283351	FAM102B	chr1	109148874	TRAPPC8	chr18	29419420	628	346
ENST00000370035	ENST00000582539	FAM102B	chr1	109148874	TRAPPC8	chr18	29419420	628	346
ENST00000405454	ENST00000283351	FAM102B	chr1	109148874	TRAPPC8	chr18	29419420	628	596
ENST00000405454	ENST00000582539	FAM102B	chr1	109148874	TRAPPC8	chr18	29419420	628	346

ORFfinder Result Based On The Fusion Transcript Sequences of the 5UTR-3CDS Fusion Genes for N-Truncated Protein Search.

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

Seq length
(transcript)

Seq length
(peptide)

ORFfinder Result Based On The Fusion Transcript Sequences of the 5CDS-3UTR Fusion Genes for C-Truncated Protein Search.

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

Seq length
(transcript)

Seq length
(peptide)

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of In-frame Fusion Genes. DeepORF is a Coding Potential Classifier Based on Convolutional Neural Network by Comparing the Real Ribo-seq Data. If the No-coding Score < 0.5 and Coding Score > 0.5, Then The In-frame Fusion Transcript is Predicted as Being Likely Translated.

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	No-coding score	Coding score
ENST00000370035	ENST00000283351	FAM102B	chr1	109148874	TRAPPC8	chr18	29419420	9.13e-03	9.91e-01
ENST00000370035	ENST00000582539	FAM102B	chr1	109148874	TRAPPC8	chr18	29419420	9.25e-04	9.99e-01
ENST00000405454	ENST00000283351	FAM102B	chr1	109148874	TRAPPC8	chr18	29419420	9.13e-03	9.91e-01
ENST00000405454	ENST00000582539	FAM102B	chr1	109148874	TRAPPC8	chr18	29419420	9.25e-04	9.99e-01

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5UTR-3CDS Fusion Genes (Potential N-Truncated Proteins).

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

No-coding score

Coding score

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5CDS-3UTR Fusion Genes (Potential C-Truncated Proteins).

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

No-coding score

Coding score

Top

Fusion Protein Retained/Non-Retained Functional Features for FAM102B_TRAPPC8

Protein Level Annotation from FGviewer
* Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at download page. Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features (visualization across fusion protein length).

No matching images found for ${hg}_${tg}.

- In-frame and retained protein feature among the 13 regional features (texts).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

FAM102B

chr1:109148874

chr18:29419420

ENST00000370035

Q5T8I3

1_142

96.0

361.0

Domain

C2 NT-type

Tgene

TRAPPC8

chr1:109148874

chr18:29419420

ENST00000283351

Q9Y2L5

302_312

1279.0

1436.0

Compositional bias

Polar residues

Tgene

TRAPPC8

chr1:109148874

chr18:29419420

ENST00000283351

Q9Y2L5

301_321

1279.0

1436.0

Region

Disordered

- Retained PPIs in in-frame fusion.

Partner

Hgene

Hbp

Tgene

Tbp

ENST

UniProt

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Hgene

Hbp

Tgene

Tbp

ENST

UniProt

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Fusion Transcript Sequence for FAM102B_TRAPPC8

In-frame Fusion Transcript Sequences.

>FAM102B_TRAPPC8_ENST00000370035_ENST00000283351_109148874_29419420 length=2681nt 
 Breakpoint=628nt
TCCCGACTCCCAGACGGGCGGCAGCGGCGGCGGAGGCGGCGGCGGCGGCGGCGGCGAGCTGAGCACCAAAAGGGCGCTCACCTCCCCGGGCGAGCTGCAGCACGACCGCTCCCCGCGGGCGGTCGGGGTCCGCGCCGCAGCTGCCGCCGC
GTTCCGGCCCAGGCTGCCGCGAGAGGCGGCGGCAGCGGCCCCGGCCGCGGCCGGCCTGCGGCGCCCCCCGGCCGCGCCCCCGCGCACAGCTCGCGGCCCCGGCCATGGGGCTGGGCTGATCCGGGGCTCGGCCAAGCTGAGGCGGCGGCG
CCCGGCCGTGCGCCCAGCTTGCAGGCGCCTGGCTCTCACGATGATGAAGAAGAAGAAGTTTAAGTTTAAGGTGGACTTCGAGCTCGAGGAGCTCTCCTCAGTGCCCTTCGTCAATGGGGTCCTCTTCTGCAAGATGCGGCTGCTGGACGG
CGGCAGCTTCACCGCCGAGTCCTCCAGGGAGGTGGTACAAGCAAACTGTGTTCGCTGGAGAAAGAAGTTCTCATTTATGTGCAAAATGAGTGCAAGTGCTGCCACAGGCATCCTAGATCCTTGTATCTACAGAGTATCCGTGAGGAAGGA
ATTAAAAGGTGGAAAAGCTTATGCAAAGGAGCCACCAGAAATGGAACTATTGAAATTTTTCAGGCCAGAAAACATTACAGTTTCCTCAAGGCCATCAGTAGAGCAGCTTTCTAGTCTCATTAAAACGAGTCTTCACTACCCAGAATCATT
TAATCATCCATTTCATCAAAAAAGCCTTTGTTTAGTACCAGTCACTCTTTTACTTTCCAATTGTTCTAAGGCTGATGTAGATGTCATAGTTGATCTTCGGCATAAAACAACAAGTCCAGAAGCACTGGAAATCCATGGATCATTCACATG
GCTTGGACAAACACAGTATAAACTTCAACTTAAAAGCCAGGAGATTCACAGTCTGCAGCTGAAAGCATGCTTTGTTCATACAGGTGTTTATAACCTTGGAACTCCTAGGGTATTTGCCAAGTTATCGGACCAAGTTACAGTGTTTGAAAC
AAGTCAGCAGAATTCCATGCCTGCCCTGATCATCATCAGTAATGTGTGACAACTTGGAAATTTGTACTGAAATCCACAATAATCAGTTTTTGCTGGATGGGTTTTACAGCAGTATTTGATATACCTAACTTGTTATGGAGGTTGATTGAT
ATCTGATCCCTGCAAAATACTTTGACTTGTCATTTTGTTGATGATGCAAAGCACGTTGGACTGAGAATACTTAACATTCTTTTTCTGTATTTCTTTAAACCCTGAGAATAATTTACATGCTCATAATACAGGATATCAGCATATTTGTGC
ACCTTATTAAGCCCCATCTTAAGAAAACACAAAGTCTAAGTCTGCTGTTACAACTTGTCAATGGTATACGAATATTAGGAGATGATTCTGAGAAAGGAAAGGCCTTGTTGGCAGTACTCCTGTTAAGCCATTAGTCTCTAAATTCCAGCT
TTACTGTGAAGTTCTATAGAGTGTTAAATACAAATTTTCCTGTCTTGCTTCACACAGTTCCTTAAAATCAGTTTTGAACTTTGGTCATAGAGTCTTCATATTTCAGTATTTGGTGGTCCCTATGACTTATACATAACTTTGTAAAAAGAA
AAAAAAATTTTTTCTGATGCTTTGAATATAGTTTTGAAAGGAGTTTTGACTTTTTTCCCCTCATTCATCTCAGTATAGAGTGCGCTATTTCACAATACGATTTTTGTCATTAAAATTACCATATTCTTTATTATATAACGTTAACTATTG
AGTTGATCTGTTTAAAATATAAATCTCAAGTTAATTAAAAATAAGCTTTTCAAAAATGTATTATATTTATAACAAATATACTGTAAATAGAATAAAGACATGCTATTCACTGTATAGCGTATTAGTATCTGTTGATTAGAAAGTCTGGTT
TCAAAATATTTTTTTATTCAGAGAATGGGCATTTGGACATAAGAAATTTCAATTCAGCCCTGCTGCAGATAGAGAAATGGGAGCAAGGTTGTTTCAATGAATATCTCTTGTCATTGGAGAAGGAGGGAAGACAGGGTGTAGGAGTGGGTG
GCAGGGAGTACAAGAGCCAGGGTCAGTCAAGTCTGGAGCAGATGGGGTCCTTGTGCCATTGACAGCTACCATGGTTTGTTCCAGTCTCAATCTCGGCACTAATCGGAGCAGACTGCACCAAAGTGGGGAGAGATCAAAAGACCCCGTTTT
CAGACTGAAGATTCCAAACCTGTACTTGGAACAACTCTTCTTGAGAGATGGGTGGCTAGTCTGTGTGCCTCTCTGCAACTGCTGCTTATGCTTCTGGATCTTAAGTGGGTCTCTGGCTTTTCAGCTCCTTCCACTCTGTGTCTTAGCAGG
TGTGGGACAAGTTGGAGAGGAAGGTCACATTCTAAGGACACTCATTTCCTTCTTGAGAGTTTAGGGCCATGGGCTTATAAAAAGTCTGAGGAGGAAAGACAAGAATGAGGAGGCATAATCACAGTGGTATCTCATATTTAAACCACTCAG
CTGAATATTAAATTGAACCGATTGTTAAACAGACACTAATAAAAAAATTAAACTATATAAACCTACAACTGAATATATTAAAAATAAAGGTAATAAAGCACTCAAAATTACTTCCTGAATATTACTCAGGA

>FAM102B_TRAPPC8_ENST00000370035_ENST00000582539_109148874_29419420 length=1264nt 
 Breakpoint=628nt
TCCCGACTCCCAGACGGGCGGCAGCGGCGGCGGAGGCGGCGGCGGCGGCGGCGGCGAGCTGAGCACCAAAAGGGCGCTCACCTCCCCGGGCGAGCTGCAGCACGACCGCTCCCCGCGGGCGGTCGGGGTCCGCGCCGCAGCTGCCGCCGC
GTTCCGGCCCAGGCTGCCGCGAGAGGCGGCGGCAGCGGCCCCGGCCGCGGCCGGCCTGCGGCGCCCCCCGGCCGCGCCCCCGCGCACAGCTCGCGGCCCCGGCCATGGGGCTGGGCTGATCCGGGGCTCGGCCAAGCTGAGGCGGCGGCG
CCCGGCCGTGCGCCCAGCTTGCAGGCGCCTGGCTCTCACGATGATGAAGAAGAAGAAGTTTAAGTTTAAGGTGGACTTCGAGCTCGAGGAGCTCTCCTCAGTGCCCTTCGTCAATGGGGTCCTCTTCTGCAAGATGCGGCTGCTGGACGG
CGGCAGCTTCACCGCCGAGTCCTCCAGGGAGGTGGTACAAGCAAACTGTGTTCGCTGGAGAAAGAAGTTCTCATTTATGTGCAAAATGAGTGCAAGTGCTGCCACAGGCATCCTAGATCCTTGTATCTACAGAGTATCCGTGAGGAAGGA
ATTAAAAGGTGGAAAAGCTTATGCAAAGGAGCCACCAGAAATGGAACTATTGAAATTTTTCAGGCCAGAAAACATTACAGTTTCCTCAAGGCCATCAGTAGAGCAGCTTTCTAGTCTCATTAAAACGAGTCTTCACTACCCAGAATCATT
TAATCATCCATTTCATCAAAAAAGCCTTTGTTTAGTACCAGTCACTCTTTTACTTTCCAATTGTTCTAAGGCTGATGTAGATGTCATAGTTGATCTTCGGCATAAAACAACAAGTCCAGAAGCACTGGAAATCCATGGATCATTCACATG
GCTTGGACAAACACAGTATAAACTTCAACTTAAAAGCCAGGAGATTCACAGTCTGCAGCTGAAAGCATGCTTTGTTCATACAGGTGTTTATAACCTTGGAACTCCTAGGGTATTTGCCAAGTTATCGGACCAAGTTACAGTGTTTGAAAC
AAGTCAGCAGAATTCCATGCCTGCCCTGATCATCATCAGTAATGTGTGACAACTTGGAAATTTGTACTGAAATCCACAATAATCAGTTTTTGCTGGATGGGTTTTACAGCAGTATTTGATATACCTAACTTGTTATGGAGGTTGATTGAT
ATCTGATCCCTGCAAAATACTTTGACTTGTCATTTTGTTGATGATGCAAAGCACGTTGGACTGA

>FAM102B_TRAPPC8_ENST00000405454_ENST00000283351_109148874_29419420 length=2681nt 
 Breakpoint=628nt
TCCCGACTCCCAGACGGGCGGCAGCGGCGGCGGAGGCGGCGGCGGCGGCGGCGGCGAGCTGAGCACCAAAAGGGCGCTCACCTCCCCGGGCGAGCTGCAGCACGACCGCTCCCCGCGGGCGGTCGGGGTCCGCGCCGCAGCTGCCGCCGC
GTTCCGGCCCAGGCTGCCGCGAGAGGCGGCGGCAGCGGCCCCGGCCGCGGCCGGCCTGCGGCGCCCCCCGGCCGCGCCCCCGCGCACAGCTCGCGGCCCCGGCCATGGGGCTGGGCTGATCCGGGGCTCGGCCAAGCTGAGGCGGCGGCG
CCCGGCCGTGCGCCCAGCTTGCAGGCGCCTGGCTCTCACGATGATGAAGAAGAAGAAGTTTAAGTTTAAGGTGGACTTCGAGCTCGAGGAGCTCTCCTCAGTGCCCTTCGTCAATGGGGTCCTCTTCTGCAAGATGCGGCTGCTGGACGG
CGGCAGCTTCACCGCCGAGTCCTCCAGGGAGGTGGTACAAGCAAACTGTGTTCGCTGGAGAAAGAAGTTCTCATTTATGTGCAAAATGAGTGCAAGTGCTGCCACAGGCATCCTAGATCCTTGTATCTACAGAGTATCCGTGAGGAAGGA
ATTAAAAGGTGGAAAAGCTTATGCAAAGGAGCCACCAGAAATGGAACTATTGAAATTTTTCAGGCCAGAAAACATTACAGTTTCCTCAAGGCCATCAGTAGAGCAGCTTTCTAGTCTCATTAAAACGAGTCTTCACTACCCAGAATCATT
TAATCATCCATTTCATCAAAAAAGCCTTTGTTTAGTACCAGTCACTCTTTTACTTTCCAATTGTTCTAAGGCTGATGTAGATGTCATAGTTGATCTTCGGCATAAAACAACAAGTCCAGAAGCACTGGAAATCCATGGATCATTCACATG
GCTTGGACAAACACAGTATAAACTTCAACTTAAAAGCCAGGAGATTCACAGTCTGCAGCTGAAAGCATGCTTTGTTCATACAGGTGTTTATAACCTTGGAACTCCTAGGGTATTTGCCAAGTTATCGGACCAAGTTACAGTGTTTGAAAC
AAGTCAGCAGAATTCCATGCCTGCCCTGATCATCATCAGTAATGTGTGACAACTTGGAAATTTGTACTGAAATCCACAATAATCAGTTTTTGCTGGATGGGTTTTACAGCAGTATTTGATATACCTAACTTGTTATGGAGGTTGATTGAT
ATCTGATCCCTGCAAAATACTTTGACTTGTCATTTTGTTGATGATGCAAAGCACGTTGGACTGAGAATACTTAACATTCTTTTTCTGTATTTCTTTAAACCCTGAGAATAATTTACATGCTCATAATACAGGATATCAGCATATTTGTGC
ACCTTATTAAGCCCCATCTTAAGAAAACACAAAGTCTAAGTCTGCTGTTACAACTTGTCAATGGTATACGAATATTAGGAGATGATTCTGAGAAAGGAAAGGCCTTGTTGGCAGTACTCCTGTTAAGCCATTAGTCTCTAAATTCCAGCT
TTACTGTGAAGTTCTATAGAGTGTTAAATACAAATTTTCCTGTCTTGCTTCACACAGTTCCTTAAAATCAGTTTTGAACTTTGGTCATAGAGTCTTCATATTTCAGTATTTGGTGGTCCCTATGACTTATACATAACTTTGTAAAAAGAA
AAAAAAATTTTTTCTGATGCTTTGAATATAGTTTTGAAAGGAGTTTTGACTTTTTTCCCCTCATTCATCTCAGTATAGAGTGCGCTATTTCACAATACGATTTTTGTCATTAAAATTACCATATTCTTTATTATATAACGTTAACTATTG
AGTTGATCTGTTTAAAATATAAATCTCAAGTTAATTAAAAATAAGCTTTTCAAAAATGTATTATATTTATAACAAATATACTGTAAATAGAATAAAGACATGCTATTCACTGTATAGCGTATTAGTATCTGTTGATTAGAAAGTCTGGTT
TCAAAATATTTTTTTATTCAGAGAATGGGCATTTGGACATAAGAAATTTCAATTCAGCCCTGCTGCAGATAGAGAAATGGGAGCAAGGTTGTTTCAATGAATATCTCTTGTCATTGGAGAAGGAGGGAAGACAGGGTGTAGGAGTGGGTG
GCAGGGAGTACAAGAGCCAGGGTCAGTCAAGTCTGGAGCAGATGGGGTCCTTGTGCCATTGACAGCTACCATGGTTTGTTCCAGTCTCAATCTCGGCACTAATCGGAGCAGACTGCACCAAAGTGGGGAGAGATCAAAAGACCCCGTTTT
CAGACTGAAGATTCCAAACCTGTACTTGGAACAACTCTTCTTGAGAGATGGGTGGCTAGTCTGTGTGCCTCTCTGCAACTGCTGCTTATGCTTCTGGATCTTAAGTGGGTCTCTGGCTTTTCAGCTCCTTCCACTCTGTGTCTTAGCAGG
TGTGGGACAAGTTGGAGAGGAAGGTCACATTCTAAGGACACTCATTTCCTTCTTGAGAGTTTAGGGCCATGGGCTTATAAAAAGTCTGAGGAGGAAAGACAAGAATGAGGAGGCATAATCACAGTGGTATCTCATATTTAAACCACTCAG
CTGAATATTAAATTGAACCGATTGTTAAACAGACACTAATAAAAAAATTAAACTATATAAACCTACAACTGAATATATTAAAAATAAAGGTAATAAAGCACTCAAAATTACTTCCTGAATATTACTCAGGA

>FAM102B_TRAPPC8_ENST00000405454_ENST00000582539_109148874_29419420 length=1264nt 
 Breakpoint=628nt
TCCCGACTCCCAGACGGGCGGCAGCGGCGGCGGAGGCGGCGGCGGCGGCGGCGGCGAGCTGAGCACCAAAAGGGCGCTCACCTCCCCGGGCGAGCTGCAGCACGACCGCTCCCCGCGGGCGGTCGGGGTCCGCGCCGCAGCTGCCGCCGC
GTTCCGGCCCAGGCTGCCGCGAGAGGCGGCGGCAGCGGCCCCGGCCGCGGCCGGCCTGCGGCGCCCCCCGGCCGCGCCCCCGCGCACAGCTCGCGGCCCCGGCCATGGGGCTGGGCTGATCCGGGGCTCGGCCAAGCTGAGGCGGCGGCG
CCCGGCCGTGCGCCCAGCTTGCAGGCGCCTGGCTCTCACGATGATGAAGAAGAAGAAGTTTAAGTTTAAGGTGGACTTCGAGCTCGAGGAGCTCTCCTCAGTGCCCTTCGTCAATGGGGTCCTCTTCTGCAAGATGCGGCTGCTGGACGG
CGGCAGCTTCACCGCCGAGTCCTCCAGGGAGGTGGTACAAGCAAACTGTGTTCGCTGGAGAAAGAAGTTCTCATTTATGTGCAAAATGAGTGCAAGTGCTGCCACAGGCATCCTAGATCCTTGTATCTACAGAGTATCCGTGAGGAAGGA
ATTAAAAGGTGGAAAAGCTTATGCAAAGGAGCCACCAGAAATGGAACTATTGAAATTTTTCAGGCCAGAAAACATTACAGTTTCCTCAAGGCCATCAGTAGAGCAGCTTTCTAGTCTCATTAAAACGAGTCTTCACTACCCAGAATCATT
TAATCATCCATTTCATCAAAAAAGCCTTTGTTTAGTACCAGTCACTCTTTTACTTTCCAATTGTTCTAAGGCTGATGTAGATGTCATAGTTGATCTTCGGCATAAAACAACAAGTCCAGAAGCACTGGAAATCCATGGATCATTCACATG
GCTTGGACAAACACAGTATAAACTTCAACTTAAAAGCCAGGAGATTCACAGTCTGCAGCTGAAAGCATGCTTTGTTCATACAGGTGTTTATAACCTTGGAACTCCTAGGGTATTTGCCAAGTTATCGGACCAAGTTACAGTGTTTGAAAC
AAGTCAGCAGAATTCCATGCCTGCCCTGATCATCATCAGTAATGTGTGACAACTTGGAAATTTGTACTGAAATCCACAATAATCAGTTTTTGCTGGATGGGTTTTACAGCAGTATTTGATATACCTAACTTGTTATGGAGGTTGATTGAT
ATCTGATCCCTGCAAAATACTTTGACTTGTCATTTTGTTGATGATGCAAAGCACGTTGGACTGA

N-Truncated Transcript (5UTR-3CDS) Sequences

C-Truncated Transcript (5CDS-3UTR) Sequences

Top

Fusion Protein Sequence for FAM102B_TRAPPC8

In-frame Fusion Protein Sequences.

>FAM102B_TRAPPC8_ENST00000370035_ENST00000283351_109148874_29419420 length=346nt
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000370035_ENST00000582539_109148874_29419420 length=346nt
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000405454_ENST00000283351_109148874_29419420 length=596nt
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIP
DEFTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCA
KKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK

>FAM102B_TRAPPC8_ENST00000405454_ENST00000582539_109148874_29419420 length=346nt
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

N-Truncated Protein (5UTR-3CDS) Sequences

C-Truncated Protein (5CDS-3UTR) Sequences

Top

Personalized Fusion Protein Sequence for FAM102B_TRAPPC8

TCGA Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

Num

Gene Group

Domain Loci

Fusion Protein ID

Fusion Gene Name

Partner

Mutated Residue in WT Protein

Seq. Length

Mutated Residue in Fusion Protein

CCLE Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

Num

Gene Group

Domain Loci

Fusion Protein ID

Fusion Gene Name

Partner

Mutated Residue in WT Protein

Seq. Length

Mutated Residue in Fusion Protein

TCGA All Mutated Fusion Protein Sequences

>FAM102B_TRAPPC8_ENST00000370035_ENST00000283351_109148874_29419420_3-gene_p.S1412P_346_S323P length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLPDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000370035_ENST00000283351_109148874_29419420_3-gene_p.S1319L_346_S230L length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPELFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000370035_ENST00000283351_109148874_29419420_3-gene_p.A1344V_346_A255V length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKVDVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000370035_ENST00000283351_109148874_29419420_3-gene_p.L1371F_346_L282F length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWFGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000370035_ENST00000283351_109148874_29419420_3-gene_p.H1354Y_346_H265Y length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRYKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000370035_ENST00000283351_109148874_29419420_3-gene_p.K1377T_346_K288T length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYTLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000370035_ENST00000283351_109148874_29419420_3-gene_p.L1287F_346_L198F length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELFKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000370035_ENST00000283351_109148874_29419420_3-gene_p.H1354R_346_H265R length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRRKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000370035_ENST00000283351_109148874_29419420_3-gene_p.E1304K_346_E215K length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVKQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000370035_ENST00000283351_109148874_29419420_3-gene_p.P1301S_346_P212S length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRSSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000370035_ENST00000283351_109148874_29419420_3-gene_p.S1382G_346_S293G length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKGQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000370035_ENST00000283351_109148874_29419420_3-gene_p.P1405S_346_P316S length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTSRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000370035_ENST00000582539_109148874_29419420_3-gene_p.S1412P_346_S323P length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLPDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000370035_ENST00000582539_109148874_29419420_3-gene_p.S1319L_346_S230L length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPELFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000370035_ENST00000582539_109148874_29419420_3-gene_p.A1344V_346_A255V length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKVDVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000370035_ENST00000582539_109148874_29419420_3-gene_p.L1371F_346_L282F length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWFGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000370035_ENST00000582539_109148874_29419420_3-gene_p.H1354Y_346_H265Y length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRYKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000370035_ENST00000582539_109148874_29419420_3-gene_p.K1377T_346_K288T length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYTLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000370035_ENST00000582539_109148874_29419420_3-gene_p.L1287F_346_L198F length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELFKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000370035_ENST00000582539_109148874_29419420_3-gene_p.H1354R_346_H265R length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRRKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000370035_ENST00000582539_109148874_29419420_3-gene_p.E1304K_346_E215K length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVKQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000370035_ENST00000582539_109148874_29419420_3-gene_p.P1301S_346_P212S length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRSSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000370035_ENST00000582539_109148874_29419420_3-gene_p.S1382G_346_S293G length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKGQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000370035_ENST00000582539_109148874_29419420_3-gene_p.P1405S_346_P316S length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTSRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000405454_ENST00000582539_109148874_29419420_3-gene_p.S1412P_346_S323P length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLPDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000405454_ENST00000582539_109148874_29419420_3-gene_p.S1319L_346_S230L length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPELFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000405454_ENST00000582539_109148874_29419420_3-gene_p.A1344V_346_A255V length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKVDVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000405454_ENST00000582539_109148874_29419420_3-gene_p.L1371F_346_L282F length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWFGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000405454_ENST00000582539_109148874_29419420_3-gene_p.H1354Y_346_H265Y length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRYKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000405454_ENST00000582539_109148874_29419420_3-gene_p.K1377T_346_K288T length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYTLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000405454_ENST00000582539_109148874_29419420_3-gene_p.L1287F_346_L198F length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELFKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000405454_ENST00000582539_109148874_29419420_3-gene_p.H1354R_346_H265R length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRRKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000405454_ENST00000582539_109148874_29419420_3-gene_p.E1304K_346_E215K length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVKQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000405454_ENST00000582539_109148874_29419420_3-gene_p.P1301S_346_P212S length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRSSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000405454_ENST00000582539_109148874_29419420_3-gene_p.S1382G_346_S293G length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKGQEIHSLQ
LKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

>FAM102B_TRAPPC8_ENST00000405454_ENST00000582539_109148874_29419420_3-gene_p.P1405S_346_P316S length=346AA
MSTKRALTSPGELQHDRSPRAVGVRAAAAAAFRPRLPREAAAAAPAAAGLRRPPAAPPRTARGPGHGAGLIRGSAKLRRRRPAVRPACRRLALTMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRW
RKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQ
LKACFVHTGVYNLGTSRVFAKLSDQVTVFETSQQNSMPALIIISNV

Fusion Protein ID	Sample ID	Mutated Partner	AAchange in WT	Seq. Length	AAchange in Fusion
ENST00000370035_ENST00000283351_109148874_29419420	TCGA-59-2351-01A	3-gene	p.S1412P	346	S323P
ENST00000370035_ENST00000283351_109148874_29419420	TCGA-61-2102-01A	3-gene	p.S1319L	346	S230L
ENST00000370035_ENST00000283351_109148874_29419420	TCGA-AX-A1CE-01A	3-gene	p.A1344V	346	A255V
ENST00000370035_ENST00000283351_109148874_29419420	TCGA-AZ-4315-01A	3-gene	p.L1371F	346	L282F
ENST00000370035_ENST00000283351_109148874_29419420	TCGA-BR-4184-01A	3-gene	p.H1354Y	346	H265Y
ENST00000370035_ENST00000283351_109148874_29419420	TCGA-BS-A0UV-01A	3-gene	p.K1377T	346	K288T
ENST00000370035_ENST00000283351_109148874_29419420	TCGA-BT-A2LB-01A	3-gene	p.L1287F	346	L198F
ENST00000370035_ENST00000283351_109148874_29419420	TCGA-CM-4744-01A	3-gene	p.H1354R	346	H265R
ENST00000370035_ENST00000283351_109148874_29419420	TCGA-DK-A1AC-01A	3-gene	p.E1304K	346	E215K
ENST00000370035_ENST00000283351_109148874_29419420	TCGA-DU-6392-01A	3-gene	p.P1301S	346	P212S
ENST00000370035_ENST00000283351_109148874_29419420	TCGA-EO-A22R-01A	3-gene	p.S1382G	346	S293G
ENST00000370035_ENST00000283351_109148874_29419420	TCGA-QB-A6FS-06A	3-gene	p.P1405S	346	P316S
ENST00000370035_ENST00000582539_109148874_29419420	TCGA-59-2351-01A	3-gene	p.S1412P	346	S323P
ENST00000370035_ENST00000582539_109148874_29419420	TCGA-61-2102-01A	3-gene	p.S1319L	346	S230L
ENST00000370035_ENST00000582539_109148874_29419420	TCGA-AX-A1CE-01A	3-gene	p.A1344V	346	A255V
ENST00000370035_ENST00000582539_109148874_29419420	TCGA-AZ-4315-01A	3-gene	p.L1371F	346	L282F
ENST00000370035_ENST00000582539_109148874_29419420	TCGA-BR-4184-01A	3-gene	p.H1354Y	346	H265Y
ENST00000370035_ENST00000582539_109148874_29419420	TCGA-BS-A0UV-01A	3-gene	p.K1377T	346	K288T
ENST00000370035_ENST00000582539_109148874_29419420	TCGA-BT-A2LB-01A	3-gene	p.L1287F	346	L198F
ENST00000370035_ENST00000582539_109148874_29419420	TCGA-CM-4744-01A	3-gene	p.H1354R	346	H265R
ENST00000370035_ENST00000582539_109148874_29419420	TCGA-DK-A1AC-01A	3-gene	p.E1304K	346	E215K
ENST00000370035_ENST00000582539_109148874_29419420	TCGA-DU-6392-01A	3-gene	p.P1301S	346	P212S
ENST00000370035_ENST00000582539_109148874_29419420	TCGA-EO-A22R-01A	3-gene	p.S1382G	346	S293G
ENST00000370035_ENST00000582539_109148874_29419420	TCGA-QB-A6FS-06A	3-gene	p.P1405S	346	P316S
ENST00000405454_ENST00000582539_109148874_29419420	TCGA-59-2351-01A	3-gene	p.S1412P	346	S323P
ENST00000405454_ENST00000582539_109148874_29419420	TCGA-61-2102-01A	3-gene	p.S1319L	346	S230L
ENST00000405454_ENST00000582539_109148874_29419420	TCGA-AX-A1CE-01A	3-gene	p.A1344V	346	A255V
ENST00000405454_ENST00000582539_109148874_29419420	TCGA-AZ-4315-01A	3-gene	p.L1371F	346	L282F
ENST00000405454_ENST00000582539_109148874_29419420	TCGA-BR-4184-01A	3-gene	p.H1354Y	346	H265Y
ENST00000405454_ENST00000582539_109148874_29419420	TCGA-BS-A0UV-01A	3-gene	p.K1377T	346	K288T
ENST00000405454_ENST00000582539_109148874_29419420	TCGA-BT-A2LB-01A	3-gene	p.L1287F	346	L198F
ENST00000405454_ENST00000582539_109148874_29419420	TCGA-CM-4744-01A	3-gene	p.H1354R	346	H265R
ENST00000405454_ENST00000582539_109148874_29419420	TCGA-DK-A1AC-01A	3-gene	p.E1304K	346	E215K
ENST00000405454_ENST00000582539_109148874_29419420	TCGA-DU-6392-01A	3-gene	p.P1301S	346	P212S
ENST00000405454_ENST00000582539_109148874_29419420	TCGA-EO-A22R-01A	3-gene	p.S1382G	346	S293G
ENST00000405454_ENST00000582539_109148874_29419420	TCGA-QB-A6FS-06A	3-gene	p.P1405S	346	P316S

CCLE All Mutated Fusion Protein Sequences

Fusion Protein ID

Sample ID

Mutated Partner

AAchange in WT

Seq. Length

AAchange in Fusion

Top

Fusion Gene Exprssed Samples for FAM102B_TRAPPC8

RNA-seq based fusion gene expressed samples.

Source	Study	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB		SKCM	TCGA-D9-A4Z5-01A	FAM102B	chr1	109148874	-	TRAPPC8	chr18	29419420	-
ChimerDB		SKCM	TCGA-D9-A4Z5-01A	FAM102B	chr1	109148874	+	TRAPPC8	chr18	29419420	-
TCGAfusionPortal		SKCM	TCGA-D9-A4Z5-01A	FAM102B	chr1	109148874	+	TRAPPC8	chr18	29419420	-
cBioPortal	SKCM_TCGA_PAN_CAN_ATLAS_2018	SKCM	TCGA-D9-A4Z5-01	EEIG2	chr1	108606252		TRAPPC8	chr18	31839457

DNA-seq based fusion gene expressed samples.

Source

Study

Disease

Sample

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

SV type

Top

Related Drugs for FAM102B_TRAPPC8

PubMed Abstract Search With ['A-B' AND 'drug'], ['A::B' AND 'drug']
* For more details on the Studied, Reported, Approved Drugs targeting this fusion gene, Go to FusionPub.

PMID

Fusion Gene Name

Drug

Study Title

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status